SCLUIBB'S 

MATERIA  MEDICA 
FOR  THE  PHYSICIAN 
AND  THE  SURGEON 


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communications    relating    to    such 
special  Work  should  be  addressed: 

Executive  Office, 

E.  R.  SQUIBB  &  SONS 

80  Beekman  Street,  New  York 


SQUIBB'S   MATERIA  MEDICA 

1919  EDITION 


SQUIBB'S 

MATERIA  MEDICA 

1919  Edition 


A  COMPLETE  ALPHABETICAL  LIST 
OF  THE  SQUIBB  PRODUCTS,  includ- 
ing all  the  articles  of  the  United  States 
Pharmacopoeia  (IXth  Revision)  and  of  the 
National  Formulary  (IVth,  1916,  edition),  to- 
gether with  the  Non-official  Chemicals,  Phar- 
maceuticals and  Newer  Remedies  in  general 
use;  setting  forth  their  Origin,  Latin  and 
English  Titles,  Synonyms,  Physical  and  Chem- 
ical Characteristics,  Incompatibilities,  Antidotes, 
Therapeutic  Indications,  Doses,  etc. 

ALSO  A  COMPREHENSIVE  DESCRIP- 
TIVE LlST  OF  TABLETS  for  Internal  and 
for  Hypodermic  Use;  of  BlOLOGICAL 

PRODUCTS,  and  of  REAGENTS,  including 

Test  Solutions,  Volumetric  Solutions  and 
Indicators. 

PUBLISHED  FOR 
THE  PHYSICIAN    AND    THE  SURGEON 

BY 
THE  MEDICAL  DEPARTMENT 

E  RSQUEBB  &  SONS.NEWYORK 

MANUFACTURING  CHEMISTS  TO  THE   MEDICAL  PROFESSION  SINCE    1858. 


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DR.  E.  R.  SQUIBB 

"The  late  Dr.  Edward  R.  Squibb  was  a  true  gentleman  of 
the  older  school,  whose  thoughts,  words  and  actions  were  guided 
by  those  sterling  qualities  of  principle,  honor  and  integrity.  One 
need  but  look  at  his  photograph  to  discern  that  he  was  a  good 
and  noble  man.  His  character  is  in  his  face.  I  honor  and 
revere  the  name  of  this  distinguished  gentleman  whose  life  work 
v/as  devoted  to  the  highest  ideals  in  the  practice  of  medicine 
and  pharmacy.  The  house  of  E.  R.  Squibb  &  Sons  stands  today 
as  a  living  monument  to  the  honor,  integrity,  zeal  and  devotion 
of  its  founder.  The  medical  and  pharmaceutical  professions 
alike  owe  a  debt  of  gratitude  to  Dr.  Edward  R.  Squibb  which 
they  can  never  pay.  Although  Dr.  Squibb  passed  on  some  few 
years  ago,  yet  he  still  lives.  In  the  business  which  he  estab- 
lished half  a  century  ago  he  lives.  His  rare  skill,  his  honor, 
his  integrity  and  his  pride  are  there.  The  influence  of  his 
noble  lire  and  character  will  never  die;  it  will  live  on  forever." 

WILLIAM  MILLER  BARTLETT 


The  E.  R.  Squibb  &  Sons 

General  Offices 
Squibb  Building,  New  York  City 


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r/  M  s  •  a  a  T*J£>B 

U, 
The  One  Hundredth  Anniversary 

of  the  Birth  of  Doctor  Squibb 

On  July  The  Fourth,  1819,  the  forty-third 
anniversary  of  Our  Nation's  birth,  was  born  of 
Quaker  parents,  in  Wilmington,  Delaware, 
Edward  Robinson  Squibb,  who,  as  a  man,  was 
destined  to  stamp  upon  pharmacy  and  medicine 
an  ethical  imprint  which  time  cannot  efface.  Re- 
ceiving good  early  education  in  the  public  schools 
of  his  native  town,  he  served  five  years  as  appren- 
tice in  pharmacy  in  the  drug  stores  of  Warder 
Morris  and  J.  M.  Sprague  of  Philadelphia, 
where  he  earned  sufficient  money  to  pay  for  a 
medical  education.  He  graduated  from  Jefferson 
Medical  College  in  1845. 

During  the  two  years  he  practiced  medicine  in 
Philadelphia  he  continued  scientific  investigation 
serving  his  alma  mater  as  Clerk  of  Clinics,  As- 
sistant Demonstrator  of  Anatomy  and  Curator  of 
The  Museum.  In  1 847  he  joined  the  U.  S.  Navy. 

On  March  29,  1 847,  Dr.  Squibb  reported  at 
the  Philadelphia  Navy  Yard  for  duty  on  board 
the  U.  S.  Brig  Perry;  and  on  April  26,  1847,  he 
received  his  appointment  as  Assistant  Surgeon,  his 
papers  being  signed  by  President  Polk.  Three 
weeks  later  he  sailed  on  an  expedition,  the  pur- 
poses of  which  were  in  connection  with  the  Mexi- 
can War  and  the  breaking  up  of  the  South  Ameri- 
can slave  trade  as  far  as  it  was  carried  on  in  vessels 
owned  in  the  United  States.  During  July,  1 849, 
The  Perry  returned  to  Hampton  Roads,  dis- 
charged at  Norfolk  and  was  put  out  of 
commission. 


in 


iv  SQUIBB'S  MATERIA  MEDICA 

On -August  11,  1849,  Dr.  Squibb  reported  at 
the  Brooklyn  Navy  Yard  for  duty  on  board  the 
Store  Ship  Erie  and  on  September  5  sailed  for 
The  Mediterranean.  While  on  this  cruise  he  was 
ordered  to  The  Frigate  Cumberland  on  which  he 
returned  to  The  Charlestown  Navy  Yard  in  July, 
1 85 1  and  left  Boston,  having  been  ordered  to  the 
Brooklyn  Naval  Hospital.  Here  he  was  assigned 
to  temporary  duty  on  the  S.  S.  Mississippi,  the 
Str.  Allegheny  and  to  Naval  Rendezvous  and 
finally  was  attached  permanently  to  the  Naval 
Hospital. 

During  Dr.  Squibb's  active  service  at  sea  he 
had  studied  how  the  national  medical  service 
could  be  improved.  Particularly,  he  had  noted 
the  poor  quality  of  ammunition  and  of  medicines 
furnished  the  Navy  and  it  was  largely  through  his 
influence  that  ammunition  and  medical  supplies 
were  exempted  from  competitive  bids,  quality  be- 
ing given  preference  to  price.  But  Dr.  Squibb 
did  more  than  this.  Not  only  did  he  exert  him- 
self to  have  good  supplies  obtained  from  outside 
sources  but  also  he  himself  endeavored  to  produce 
trustworthy  pharmaceuticals.  Consequently  he 
established  a  laboratory  in  an  outbuilding  belong- 
ing to  the  Naval  Hospital,  equipping  it  largely 
with  apparatus  of  his  own  manufacture  or  of  his 
own  invention. 

In  1853,  at  this  Naval  Laboratory  Dr.  Squibb 
perfected  the  still  which  he  had  devised  for  the 
making  of  the  Squibb  Ether,  whicK  was  soon  rec- 
ognized to  be  and  still  is  The  Standard  Anaes- 
thetic Ether.  Here  also  he  made  the  Squibb  stills 
for  the  manufacture  and  purification  of  Chloro- 
form and  his  original  process  produces  after  all 


SQUIBB'S  MATERIA  MEDICA  v 

these  years  the  best  anaesthetic  chloroform,  one 
safer  and  otherwise  better  than  that  of  the  U.  S. 
P.  Here  he  devised  also  methods  and  apparatus 
for  subliming  benzoic  acid  and  for  making  cal- 
cium chloride;  also,  he  invented  and  built  mills 
for  powdering  drugs  of  all  sorts.  He  discovered 
and  established  suitable  methods  for  producing 
phosphoric  acid  and  for  crystallizing  ammonium 
phosphate.  As  today,  so  sixty  years  ago,  Dr. 
Squibb's  mercurials  were  unequalled ;  and  the  pro- 
cesses worked  out  and  perfected  by  Dr.  Squibb 
for  the  making  of  extracts  and  fluidextracts  have 
not  been  improved  upon  since  his  day.  To  men- 
tion the  perfection  of  aconite  and  ergot  prepara- 
tions, and  of  other  pharmaceutical  products  and 
processes,  all  from  Dr.  Squibb's  own  brain  and 
hands,  while  of  great  interest,  would  occupy  a 
treatise  by  itself. 

From  the  start,  then,  Dr.  Squibb  was  success- 
ful in  producing  pharmaceuticals  and  chemicals 
of  the^  finest  quality.  The  Historian  in  the  U.  S. 
Naval  Medical  Bulletin  Vol.  IX,  No.  3,  writes, 
"At  first  only  a  few  standard  mediums  were  pre- 
pared for  themse  of  the  Naval  Hospital  at  Brook- 
lyn, but  gradually,  other  hospitals  were  supplied 
until  the  value  (of  the  Squibb  Laboratory)  be- 
ing recognized  Congress  authorized  the  Navy  De- 
partment to  establish  a  larger  pharmaceutical  lab- 
oratory for  the  manufacture  of  important  articles 
on  the  supply  table."  In  this  new  laboratory  Dr. 
Squibb,  the  instigator  and  founder  became  the 
chief  factor  and  here  he  worked  until  he  entered 
civil  life  to  establish  his  own  laboratory. 

In  1857  Dr.  Squibb  resigned  his  naval  posi- 
tion. Soon  after  its  establishment  Congress  closed 


vi  SQUIBB'S  MATERIA  MEDICA 

the  laboratory  which  had  been  established  at  the 
Naval  Hospital.  The  War  Department,  how- 
ever, impressed  with  the  utility  of  the  laboratory 
as  established  by  Dr.  Squibb  and  with  the  un- 
equalled quality  of  the  drugs  produced  by  him, 
sought  to  re-establish  it  but  failed  on  account 
of  political  opposition.  It  was  then  that  Dr. 
R.  S.  Satterlee,  Chief  Medical  Purveyor  of  the 
Army,  persuaded  Dr.  Squibb  to  establish  a  labo- 
ratory of  his  own.  Dr.  Satterlee  assured  Dr. 
Squibb  that  if  he  would  make  drugs  of  as  good  a 
quality  as  he  made  in  the  Naval  Laboratory,  the 
U.  S.  Government  would  buy  of  him  such  prod- 
ucts as  it  might  need.  Consequently  in  1 858  The 
Squibb  Chemical  and  Pharmaceutical  Labora- 
tories were  established  and  The  House  of  Squibb 
was  founded. 

For  nearly  fifty  years  Dr.  Squibb  personally 
worked  in  his  own  establishment.  Soon  after  be- 
ginning his  work  a  fire  which  started  in  the  ether 
house  destroyed  the  laboratories  and  severely  in- 
jured Dr.  Squibb.  However,  he  rebuilt  his 
laboratories  and  although  crippled  and  rendered 
a  constant  sufferer  he  continued  to  labor  and 
toiled  faithfully  in  the  interest  of  scientific  phar- 
macy and  medicine  until  his  death,  which  oc- 
curred on  October  25,  1 900. 

Although  Dr.  Squibb  is  no  more  he  lives  in- 
the  laboratories  which  he  established,  and  those 
upon  whom  his  mantle  has  fallen  carry  on  the 
work  as  conscientiously  as  he  did,  being  actuated 
by  the  same  motives,  governed  by  the  same  policy 
and  making  the  same  earnest  effort  to  spread  the 
influence  which  originated  with  Dr.  E.  R.  Squibb. 


The   Sixtieth   Anniversary  of    the 
Founding  of  the  House  of  Squjbh 

It  is  now  sixty  years  since  the  House  of  E.  R. 
Squibb  and  Sons  was  founded.  Instituted  not 
merely  for  business,  the  object  of  which  is  profit, 
it  began  its  career  with  unique  intentions.  Its  in- 
ception was  in  a  sense  of  duty.  The  circumstances 
in  which  Dr.  Squibb  found  himself  when  at  the 
Brooklyn  Naval  Hospital  made  him  realize  that 
as  a  citizen  and  as  a  naval  officer  he  owed  to  his 
country  an  effort  to  better  certain  conditions,  and 
this  obligation  he  immediately  set  about  to  fulfil. 

The  integrity  of  the  products  made  and  offered 
by  Dr.  Squibb  gained  for  the  Squibb  Labora- 
tories the  confidence,  not  only  of  the  United 
States  Government,  but  of  physicians  and  surgeons 
in  civil  practice  as  well.  Quality,  which  to  Dr. 
Squibb  had  always  been  first  in  importance,  was 
appreciated  by  others.  He  had  realized  that  in 
the  treatment  of  the  sick  the  physician  was  handi- 
capped unless  he  had  at  hand  remedies  which  were 
true  to  their  formulae  and  of  known  potency. 
And  when  the  physician  himself,  by  using  the 
Squibb  drugs,  saw  their  effect,  he,  too,  understood 
the  necessity  of  trustworthy  products.  Thus  the 
Squibb  ideal  proved  a  success. 

Because  of  this,  it  always  has  been  a  principle 
of  the  Squibb  Laboratories  to  select,  with  the 
most  scrupulous  care,  all  crude  materials  used  in 
manufacture  and  also  to  devise  correct  methods 
of  manufacturing. 

In  order  further  to  assure  perfect  results,  Dr. 
Squibb  established  a  Control  Laboratory,  in  which 


Vll 


viii         SQUIBB'S  MATERIA  MEDICA 

experienced  chemists  are  employed  to  examine 
and  test  every  lot  of  each  product  as  soon  as  it  is 
made  and  before  it  is  put  into  stock.  This  was  an 
additional  check  on  the  quality  of  the  finished 
drug;  therefore,  each  article  which  bears  the 
Squibb  label  represented  then,  as  to-day,  a  prod- 
uct in  strict  conformity  with  highest  standards. 

The  rapid  and  wide-spread  demand  for  drugs 
of  Squibb  Quality  soon  made  expansion  impera- 
tive, so  that  to-day  not  only  are  the  original  labo- 
ratories enlarged,  but  new  ones  have  sprung  up 
in  various  parts  of  the  Union.  For  instance,  The 
Squibb  Chemical  and  Pharmaceutical  Labora- 
tories, located  in  Brooklyn,  occupy  an  entire  block 
with  overflows  in  other  parts  of  the  city.  The 
Squibb  Chemical,  Biological  and  Research 
Laboratories,  located  in  New  Brunswick,  New 
Jersey,  occupy  over  fifty-six  acres.  In  these 
New  Brunswick  Laboratories  are  made  the 
Squibb  Biological  and  Bacteriological  Products, 
including  the  Squibb  Antitoxins,  Serums,  Vac- 
cines, Leucocyte  Extract,  etc.,  etc.  Also  the 
Squibb  Mercurials  including  Mercury  Bi- 
chloride, Calomel,  etc.  Also  the  Dakin 
Chlorinated  Antiseptics  and  Disinfectants,  in- 
cluding Chloramine-T,  Dichloramine-T,  Chlor- 
cosane,  Halazone,  etc.  Further,  in  New  Bruns- 
wick, N.  J.,  is  located  the  Squibb  Ether  Plant, 
whence  comes  the  Squibb  Ether,  of  one  quality 
only,  the  best  that  can  be  made  for  anaesthesia. 

At  Berlin,  N.  H.,  are  the  Laboratories  for  the 
manufacture  of  the  Squibb  Chloroform,  located 
there  because  in  Berlin,  N.  H.,  there  is  available 
the  purest  chlorine  at  the  lowest  cost. 

At  Richmond,  Cal.,  are  situated  the  Labora- 


SQUIBB'S  MATERIA  MEDICA  ix 

tories  for  the  purifying,  testing,  bottling  and  ship- 
ping of  The  Squibb  Mineral  Oil,  known  as 
Liquid  Petrolatum  Squibb,  Heavy  ( Calif ornian). 
These  laboratories  are  located  there  because  only 
in  California  is  found  the  naphthene  oil,  a  hydro- 
carbon superior  not  only  to  all  other  American 
mineral  oils,  but  also  to  the  Russian  oils.  From 
this  Californian  highest  quality  crude  is  specially 
refined  under  Squibb  Control,  for  internal  use,  the 
unequalled  Squibb  Mineral  Oil,  which  main- 
tains a  high  and  correct  viscosity  in  the  intestine, 
where  it  does  its  work. 

That  the  Squibb  policy  of  maintaining  Uniform 
Purity  and  Efficacy  and,  therefore,  Full  Relia- 
bility directs  all  the  activities  of  the  Squibb 
Laboratories  is  apparent  from  what  has  been  said 
above;  it  is  evident  also  from  the  fact  that  when 
the  Pure  Food  and  Drugs  Act  was  passed  in 
1906,  The  House  of  Squibb  did  not  have  to 
change  any  of  its  standards,  and  it  is  a  matter 
of  record  that  the  products  supplied  under  the 
Squibb  Label  always  have  been  and  still  are  of 
a  quality  better  than  that  which  is  demanded  by 
the  United  States  Pharmacopoeia  and  by  other 
recognized  authorities. 

It  must,  therefore,  be  obvious  that  the  Squibb 
Laboratories  are  devoted  exclusively  to  the  pro- 
duction of  medicinal  agents  of  the  highest  qual- 
ity, true  to  their  name  and  their  formulae,  products 
the  best  that  can  be  made  for  the  purposes  in- 
tended: and  that  in  this  way  the  Squibb  Labora- 
tories are  endeavoring  to  serve  efficiently  the  medi- 
cal profession  in  whatever  manner  such  service  can 
be  rendered  most  acceptably. 

E.  R.  SQUIBB  &  SONS. 


Foreword 

SQUIBB'S  MATERIA  MEDICA  is,  in  part,  a 
conspectus  of  the  products  of  the  Squibb  Labo- 
ratories. In  addition,  however,  to  descriptions  of 
these  Squibb  products,  which  consist  of  prepara- 
tions of  the  U.  S.  P.  and  of  the  N.  F.  and  also  of 
many  other  approved  medicinal  chemicals,  galen- 
icals, etc.,  there  are  given  facts  relating  to  a  large 
number  of  non-official  and  newer  remedies  which 
are  approved  by  the  Council  of  Pharmacy  and 
Chemistry  of  the  American  Medical  Association, 
but  which  are  not  offered  under  the  Squibb  label. 

While  the  scope  of  SQUIBB'S  MATERIA 
MEDICA  is  very  broad,  it  gives  full  yet  concise 
information  concerning  each  product.  Of  this  it 
sets  forth  source;  physical,  chemical  and  phar- 
maceutical characteristics ;  therapeutic  uses ;  doses ; 
incompatibilities;  antidotes;  etc.  It  is,  therefore, 
a  trustworthy  compendium  of  the  approved  ma- 
teria  medica  of  to-day  and  if  kept  at  hand  for 
ready  reference,  will  prove  to  be  a  valuable  aid 
to  the  physician  in  prescribing  and  of  practical 
use  to  the  pharmacist  in  compounding. 

This  1919  edition  of  SQUIBB'S  MATERIA 
MEDICA,  in  the  character  and  the  arrangement 
of  its  contents,  is  similar  to  its  predecessors.  How- 
ever, a  large  number  of  additions  have  been  made 
to  it,  and  the  names  of  such  products  as  have 
become  obsolete,  since  the  preceding  edition  was 
issued,  have  been  omitted.  All  descriptive  notes 


XI 


xii          SQUIBB'S  MATERIA  MEDICA 

have  been  revised  carefully  and  those  which  con- 
cern official  products  now  accord  with  the  U.  S.P. 
IXth  Revision,  which  became  official  Septem- 
ber 1,  1916.  The  list  of  these  is  complete. 

As  regards  the  preparations  of  the  National 
Formulary,  all  are  listed  and  described,  but  only 
those  which  are  considered  satisfactory  from 
pharmaceutical  and  therapeutical  standpoints,  or 
which  are  in  more  or  less  common  use  by  the 
medical  profession,  are  made  and  sold  by  us. 

On  the  following  pages  the  names  of  all  prod- 
ucts which  are  made  by  us  and  furnished  under 
the  Squibb  Label  are  printed  in  bold  type,  fol- 
lowed by  the  word  Squibb  thus : 

Bismuth    Subcarbonate     Squibb 

while  the  names  of  products  not  offered  by  us 
but  which  are  included  in  the  list  in  order  that  it 
may  be  complete,  are  printed  in  lighter  face  type, 
thus: 

BENZIN,    PETROLEUM,    PURIFIED. 

The  description  of  an  article  of  the  U.  S. 
Pharmacopoeia  begins  with  its  Latin  title  simply; 
the  description  of  an  article  of  the  National  For- 
mulary  begins  with  its  Latin  title  followed  by 
N.  F. ;  while  in  the  case  of  a  product  which  is 
neither  U.  S.  P.  nor  N.  F.  the  Latin  title  is 
omitted. 

The  chemical  formula  of  the  product  described 
is  given  whenever  possible. 

By  "Average  Dose"  is  meant  the  dose  given 
in  the  U.  S.  P.  IXth  Rev.  or  in  the  N.  F.  IVth 
Ed.  The  word  "Dose"  alone  indicates  that  no 
dose  is  given  by  the  U.  S.  P.  or  the  N.  F.  and 


SQUIBB'S  MATERIA  MEDICA         xiii 

that  the  dose  suggested  is  that  approved  by  those 
considered  to  be  authority. 

It  should  be  borne  in  mind  while  using 
SQUIBB'S  MATERIA  MEDICA  that  each  Squibb 
product  is  made  from  first  quality  crude  material, 
selected  in  accordance  with  the  Squibb  standards 
for  crude  drugs,  and  is  worked  by  experts  who 
exercise  the  most  scrupulous  care  in  each  step 
necessary  to  produce  a  therapeutically  active 
product. 

Medicinal  Tablets  have  become  an  essential 
part  of  the  physician's  armamentarium.  The  list 
of  the  Squibb  Tablets  comprises  not  only  those 
composed  of  a  single  drug  but  also  some  approved 
combinations  which  are  recommended  and  em- 
ployed by  internists. 

In  the  manufacture  of  these  Squibb  tablets, 
only  drugs  of  the  Squibb  quality  are  used  and 
only  expert,  skill  is  employed  in  their  production. 
Since  experience  has  proved  that  in  the  majority 
of  cases  carefully  controlled  compression  pro- 
duces the  best  tablet,  we  make  use  now  of  this 
method  except  in  a  very  few  instances  in  which 
the  "moulded  form"  offers  some  advantage. 

The  coating  of  the  Squibb  tablets,  listed  as 
"coated,"  completely  masks  the  taste  of  the  drugs 
contained  in  the  tablet;  prevents  loss  of  volatile 
ingredients;  and  hinders  chemical  reaction  be- 
tween ingredients  which  should  be  kept  separate 
until  in  the  stomach,  e.g.,  Blaud's  Tablets.  Tab- 
lets Blaud  Squibb  are  efficacious  without  excep- 
tion and,  therefore,  are  preferred  by  all  internists. 
The  reason  for  this  is,  the  iron  and  alkali  car- 
bonate are  so  mingled  and  the  tablet  so  coated 


xiv         SQUIBB'S  MATERIA  MEDICA 

that  no  combination  of  the  two  takes  place  until, 
after  swallowing,  the  two  chemicals  are  released 
and  nascent  ferrous  carbonate  is  .formed  in  the 
gastro-intestinal  tract. 

Because  of  the  method  of  manufacture  and  the 
permanent  solubility  of  the  coating  all  Squibb 
Tablets,  coated  or  uncoated,  may  be  depended 
upon  to  disintegrate  quickly  and  completely  in 
the  stomach,  thus  insuring  speedy  therapeutic 
action.  This  is  true  even  of  those  tablets  which 
contain  insoluble  medicaments  such  as  acetanilid, 
bismuth  salts,  acetphenetidin,  salol,  and  the  like. 

The  Titles  of  the  Squibb  Tablets  deserve  at- 
tention and  study.  In  accordance  with  the  ethi- 
cal principles  formulated  by  the  American 
Medical  Association,  we  have  adopted  pharma- 
ceutical titles  in  all  instances  and  have  discarded 
from  the  labels  titles  derived  from  diseases  for 
which  the  tablet  may  be  used  or  which  other- 
wise might  be  therapeutically  suggestive. 

Biologkal  Products,  while  comparatively  new 
as  remedial  agents,  are  now  recognized  to  be  very 
valuable  for  the  treatment  of  certain  diseases. 
The  Squibb  list  of  Biologicals  includes  all  that 
to-day  are  recognized  to  be  of  value  and  they  are 
classed  as  Antitoxins;  Serums;  Bacterial  Vac- 
cines (Bacterins) ;  Haemostatics,  as  Thrombo- 
plastin;  also  Leucocyte  Extract;  Smallpox  Vac- 
cine, and  Pasteur's  Anti-Rabic  Treatment. 

Trustworthy  Reagents  are  of  prime  impor- 
tance in  any  laboratory  work.  Therefore  we 
have  added  to  our  list  certain  Analyzed  Reagents. 
As  the  quantity  of  impurity  in  chemicals  used 
for  reagents  is  small,  the  amount  taken  for  analy- 


SQUIBB'S  MATERIA  MEDICA          xv 

sis  may  not  be  sufficiently  large  to  make  the  im- 
purity apparent.  It  is  noteworthy  then,  that  of 
the  Squibb  Analyzed  Reagents,  enough  is 
analyzed  to  insure  either  the  absence  of  any  im- 
purity or  an  accurate  determination  of  the  amount 
present.  On  our  labels  either  the  absence  or  the 
exact  amount  of  impurity — together  with  the 
quantity  analyzed — is  stated.  No  labels  are  kept 
in  stock.  New  labels  are  printed  for  each  lot  of 
reagents  analyzed. 

E.  R.  SQUIBB  &  SONS. 
January,  1919. 


PART  I 

\ 

Drugs  and  Chemicals 

Comprising  Drugs,  Chemicals  and  Pharma- 
ceuticals of  the  United  States  Pharmacopoeia 
IXth  Revision  and  the  National  Formulary 
IVth  Edition,  Together  With  Some  Non- 
Official  and  New  Remedies  in  General  Use 


The  DOSES  are  those  for  adults  by  the  mouth,  unless 
otherwise  stated.  Of  the  official  products  the  average 
doses  as  published  in  the  U.  S.  Pharmacopoeia  IXth 
Revision  and  the  National  Formulary  IVth  Ed.  are  given. 

To  determine  the  fraction  of  the  adult  dose  suitable  for 
children  of  different  ages,  divide  the  age  (in  years)  by 
12  plus  the  age.  Thus:  for  a  child  2  years  old  the 
proportionate  dose  is  2  divided  by  (12-)-2),  or  1/7 
that  for  adults. 

In  the  case  of  powerful  narcotic  drugs  about  one-half 
this  proportion  holds;  whereas  of  cathartics  two  or  three 
times  this  proportion  is  usual;  and  children  also  bear 
belladonna  preparations,  pilocarpine,  arsenic  and  mer- 
cury well. 

The  dose  for  hypodermic  injection  is  ordinarily  one- 
half  to  two-thirds,  the  rectal  dose  one  and  a  half  to 
double,  that  by  mouth. 

"Av.  Dose,"  or  "Aver.  Dose,"  stands  for  average 
dose;  "Cc."  for  cubic  centimeter;  "Gm."  for  gramme 
or  grammes;  "gr."  for  grain  or  grains;  "mil"  (the  new 
U.  S.  P.  succedaneum  for  "Cc.")  for  milliliter;  "min." 
for  minim  or  minims;  "g.  s."  for  glass-stopper. 

The  solubility  statements  apply  at  25 °C. 

An  *  indicates  the  form  supplied  on  unspecified  orders. 

Those  products  whose  titles  are  preceded  by  an  © 
are  included  in  "Useful  Drugs,"  prepared  under  the 
direction  and  supervision  of  the  Council  on  Pharmacy 
and  Chemistry  of  the  American  Medical  Association. 

A  f  means  that  the  item  is  covered  by  the  Harrison 
Law,  and  therefore  must  be  ordered  on  the  official  nar- 
cotic order  blank. 

xvi 


SQUIBB'S  MATERIA  MEDICA  I 

ABSINTHIUM. 

Absinthium,  N.  F.;  Wormwood;  Madderwort;  Vermuth. 
Dried  leaves  and  flowering  tops  of  Artemisia  Absinthium 
(Fam.  Composite).  Aromatic  odor;  very  bitter  taste.  Ace. 
to  Council  on  P.  &  C.  of  A.  M.  A.,  absinthium  is  an  "obsolete 
aromatic  bitter,  without  advantage  over  gentian."  Average 
Dose:  30  grains  (2  Gm.). 

©  Acacia,   Squibb 

*  Granulated  or  Powdered  carton.  lb.         ;  ]/£  lb. 

Acacia;  Gum  Arabic;  Gum  Acacia.  Dried  gummy  exuda- 
tion from  Axacia  Senegal  and  other  African  species  of  Aca- 
cia. Great  care  is  exercised  in  selecting  a  good  market  grade. 
Dirt  and  pieces  of  bark  and  twigs,  invariably  present  in  the 
whole  tears,  are  completely  removed  by  a  special  process  be- 
fore granulating  or  powdering  the  gum;  hence  the  article  here 
offered  is  exceedingly  acceptable  for  pharmaceutical  use.  Solu- 
ble slowly  and  almost  completely  in  2  parts  water;  insoluble 
in  alcohol,  ether,  oils.  Demulcent;  Vehicle  for  water-insoluble 
substances;  Emulsifier;  Adhesive.  Incompatible  with  mineral 
acids,  alcohol,  ether,  ammonia,  tartar  emetic,  strongly  alcoholic  or 
ethereal  tinctures,  fluidextracts. 

ACETAMIDOSALOL.     See  Salophen. 

©  Acetanilid,  Squibb 

*  Crystals  or  Powdered  carton,  lb.          ;  %  lb. 

Acetanilidum ;  Phenylacetamide;  Antifebrin.  CgHgNO.  Mon- 
acetyl  derivative  of  aniline.  1  Gm.  dissolves  in  190  mils 
(Cc.)  water,  3.4  alcohol,  3.7  chloroform,  5  glycerin,  17  ether. 
Antipyretic,  Analgesic,  Wound  Antiseptic.  Average  Dose: 
0.2  Gm.  (3  grs.)  When  mixed  with  nitrous  ether,  acetanilid 
yields  a  solution  turning  yellow  then  red  on  standing.  Antidotes : 
stimulants;  atropine  or  strychnine  subcutaneously ;  oxygen.  (See 
also  Powder;  Tablets  [Part  II].) 

Acetone,  Squibb  tin,  lb.         ;  |4  lb. 

Acelonum;  Dimethylketone.  Not  less  than  99  percent.  CsHfjO. 
Perfectly  free  from  empyreumatic  substances,  and  containing 
no  weighable  impurities.  Sp.  gr.  about  0.790.  Miscible  with 
water,  alcohol,  ether,  chloroform,  most  volatile  oils.  Inflam- 
mable. Keep  protected  from  fire.  Pharmaceutical  Solvent, 
Reagent. 

ACETONE-CHLOROFORM.      See  Chlorbutanol   (Chloretone). 


This  house  supplies  only  one  quality  of  each  product:  that  best 
suited  to  the  purposes  intended.  The  specification  "Squibb's" 
is  not  open  to  various  interpretations ;  it  has  a  plain,  posi- 
tive meaning.  Therefore,  when  prescribing,  specify  SQUIBB'S. 


2  SQUIBB'S  MATERIA  MEDICA 

ACETOZONE. 

Acetyl-benozyl  Peroxide.  Soluble  in  1000  parts  water,  20  oil, 
slightly  in  alcohol,  moderately  in  ether  or  chloroform,  but  slowly 
decomposing  in  these  solvents  and  on  contact  with  alkalies  and 
organic  matter.  Marketed  only  as  50  percent,  mixture  with 
inert  absorbent  powder.  Antiseptic,  Disinfectant.  Dose:  3  to 
5  grains  (0.2  to  0.3  Gm.),  usually  in  dilute  solution. 

0  Acetphenetidin,  Squibb  carton,  oz. 

Acetphenelidinum ;  Acetparaphenetidin;  Para- Acetphenetidin; 
Phenacetin.  CioHisNOo.  Monacetyl  derivative  of  para- 
amidophenetol.  White,  shining,  odorless,  tasteless,  crystalline 
powder.  I  Gm.  dissolves  in  1310  mils  (Cc.)  water,  15  alco- 
hol, 14  chloroform,  90  ether.  Antipyretic,  Analgesic. 
Average  Dose:  5  grains  (0.3  Gm.).  Antidotes:  same  as  of 
A«tanilid.  (See  also  Tablets  [Part  II].) 

ACET-THEOCIN-SODIUM. 

Soluble  Theocin.  White  powder;  60  percent,  theocin.  Soluble 
in  about  20  parts  water;  insoluble  in  alcohol,  ether.  Acids 
precipitate  theocin.  Diuretic.  Dose:  3  to  5  gr.  (0.2  to  0.3  Gm.). 

ACET-THEOPHYLLIN-SODIUM.     Same  as  Acet-theocin-sodium. 

0  Acid  Acetic,  Squibb 

bottle,  5  Ibs.,  per  Ib.          ;  Ib.          ;  ]4  Ib. 

AciJum  Acelicum.  36  to  37  percent.  CoH-jOo.  Caustic, 
Rubefacient;  in  diluted  form  (vinegar),  antidote  to  alkalies. 
Average  Dose:  5  minims  (0.3  mil  [Cc.]),  diluted. 

Acid  Acetic  Anhydride,  Reagent.     See  Reagents  (Part  IV). 

ACID   ACETIC    DILUTED. 

Acidum  Acelicum  Dilulum.  Assays  5.7  to  6.3  percent. 
CjH-tOi;.  Miscible  with  water  or  alcohol.  Refrigerant, 
Astringent.  Average  Dose:  30  minims  (2  mils  [Cc.]). 

Acid  Acetic  Glacial,  Squibb 

g.  s.  bottle,  Ib.  ;  %  Ib.  ;  oz. 

Acidum\  Acelicum  Claciale.  The  strongest  acid  obtainable  by 
redistillation  is  subjected  to  careful  recrystallization,  which  raises 
its  strength  to  99.5  percent,  (as  against  99  percent,  in  U.  S.  P.) 
and  shuts  out  impurities.  Caustic,  pure.  Antidotes :  magnesia, 
chalk,  soap  and  water,  or  lime  water;  emetics;  oil  and  demul- 
cents. (See  also  Reagents  [Part  IV].) 

0  Acid  Acetylsalicylic,  Squibb 

bottle,  Ib.  ;  |4  N>-  ;  oz. 

Acetylsalicylic  Acid,  CgHsO.^  is  commonly  known  by  the 
trade  name  "  Aspirin."  The  article  here  offered  is  of  high- 
est purity;  free  from  uncombmed  salicylic  acid.  White, 
odorless  needles;  acidulous  taste.  Soluble  in  about  300  parts 
water,  3  alcohol,  20  ether;  readily  in  chloroform.  Decomposed 
by  heat,  moisture,  diluted  acids,  alkalies  and  their  carbonates 
and  bicarbonates.  Antirheumatic,  Analgesic,  Antipyretic,  like 
salicylic  acid,  but  better  borne  it  is  claimed.  Dose:  5  to  15 
grains  (0.3  to  1  Gm.).  Should  not  be  dispensed  with  quinine 
or  its  salts,  lest  poisonous  quinotoxin  be  formed.  (See  also 
Tablets  [Part  II].) 


SQUIBB'S  MATERIA  MEDICA  3 

Acid    Arsenous.       See    Arsenic    Trioxide. 

©  Acid  Benzoic,  Squibb          tin,  lb.         ;  |4  lb.         ;  oz. 

Synthetic  (from  toluol).  Solubility,  dose,  etc.:  same  as  of 
following. 

0  Acid  Benzoic  from  Benzoin,  Squibb 

tin,  lb.         ;  14  lb.          ;  oz. 

Acldum  B'enzoicum ;  Flowers  of  Benzoin.  CyHcOo.  True 
or  natural  Benzoic  Acid,  obtained  from  gum  benzoin  by 
sublimation.  White  or  yellowish,  lustrous  scales;  pungent,  acid 
taste.  1  Gm.  dissolves  in  275  mils  (Cc.)  water,  2.3  alcohol, 
4.5  chloroform,  3  ether,  23  oil  turpentine;  soluble  in  oils. 
Borax  or  sodium  phosphate  increases  aqueous  solubility.  Anti- 
septic, Diuretic.  Average  Dose:  8  grains  (0.5  Gm.).  Keep 
well  stoppered,  in  cool  place.  Readily  volatilizes  in  warm 
room;  darkens  on  exposure  to  light. 

Acid  Boracic.        See  Acid  Boric. 

®  Acid  Boric,  Squibb 

Granulated  or  *  Impalpable  Powder 

tin,  lb.          ;  %  lb. 

Impalpable  Powder  3-oz.  sifter  top  tins,  per  doz. 
Acldum  Boricum ;  Boracic  Acid.  HsBOs.  Very  high  grade, 
carefully  recrystallized  and  free  from  borax,  chlorides,  sul- 
phates, heavy  metals,  etc.  Notwithstanding  the  well-known 
difficulty  of  pulverizing  boric  acid,  due  to  the  peculiarly  slip- 
pery character  of  the  crystals,  the  powdered  acid  here  offered 
has  b«en  reduced  to  an  impalpable  powder  in  chaser  mills,  being 
what  is  termed  an  'air-floated"  powder,  the  finest  it  is  possible 
to  produce.  This  form  is  very  desirable  for  use  as  a  dusting 
powder,  for  insufflation,  for  antiseptic  dressings,  in  eye 
surgery  and  in  prescription  work  generally.  1  Gm.  dissolves 
in  18  mils  (Cc.)  waJer,  18  alcoSol,  4  glycerin.  Mild  Anti- 
septic and  Astringent.  Used  in  conjunctivitis,  cystitis,  wounds, 
etc.  Average  Dose:  8  grains  (0.5  Gm.).  (See  also  Reagents 
[Part  IV];  Tablets  [Part  II].) 

ACID  BROMAURIC. 

AciJum  Bromauricum,  N.  F.  HAuBr4-5HoO.  Dark  red- 
brown,  odorless  crystals  or  granular  masses;  metallic,  acid  taste; 
32  percent,  gold.  Melts  at  about  27°  C.  Very  soluble  in 
water,  alcohol.  Asserted  Alterative,  but  employed  principally 
for  preparing  Solution  Gold  and  Arsenic  Bromide.  Average 
Dose:  l/io  grain  (0.006  GM.). 


The  prices  of  the  Squibb  Products  are  in  all  instances  as  low  as 
the  quality  and  quantity  of  ingredients  and  the  expense  of  man- 
ufacture allow.  They  include  containers,  packing  and  boxing.  When 
ordering  or  prescribing  medicinal  products,  specify  SQUIBB'S. 


4  SQUIBB'S  MATERIA  MEDICA 

Acid  Carbolic  Crude,  Solution.      See    Solution   Acid    Car- 
bolic. 

Acid   Carbolic  Crystals.     See  Phenol. 

ACID    CARBOLIC    IODIZED.      See    Phenol    Iodized. 

ACID  CHROMIC.     See   Chromium    Trioxide. 

Acid  Chromic  Reagent.  See  Reagents  (Part  IV). 

ACID     CHRYSOPHANIC,  so-called.     See    Chrysarobin. 

0Acid  Citric  (Cryst.),  Squibb  bottle,  Ib.  ;  J4  Ib. 
Acidum  Ciiricum.  C(jHgO7.H2O.  Tribasic  organic  acid  usu- 
ally obtained  from  juice  of  limes  or  lemons.  Recrystallized. 
(99.5  percent.).  1  Cm.  dissolves  in  0.5  mil  (Cc.)  water,  1.8 
mils  alcohol,  30  ether;  freely  soluble  in  glycerin.  Antiscorbutic; 
substitute  for  lemon  juice,  and  for  diluted  hydrochloric  acid 
in  hypoacidity.  Average  Dose:  8  grains  (0.5  Gm.). 
Used  externally  pure  or  in  5  to  10  percent,  solutions.  (See 
also  Reagents  [Part  IV].) 

Acid  Cresylic.        See  Cresol. 

ACID  DIETHYLBARBITURIC.    See  Barbital. 

ACID  FORMIC. 

Acidum  Formicum,  N.  F.  24  to  26  percent.  HCOOH.  Clear, 
colorless,  strongly  acid  liquid;  pungent  odor;  sp.  gr.  about 
1.058.  Miscible  with  water,  alcohol,  glycerin.  Caustic  irri- 
tant; Diuretic.  Average  Dose:  5  minims  (03  mil). 

Acid    Gallic,    Squibb  carton,  Ib.          ;  J4  Ib.         '>  oz- 

Acidum  Callicum;  Trihydroxybenzoic  Acid.  CyHciO.-j.HoO. 
Prepared  from  tannic  acid,  of  high  purity,  and  free  from  tan- 
nin. 1  Gm.  dissolves  in  87  mils  (Cc.)  water,  4.6  alcohol, 
10  glycerin,  100  ether;  almost  insoluble  in  chloroform.  Astrin- 
gent. Average  Dose:  15  grains  (1  Gm.).  Applied  topically 
pure  or  in  strong  solution.  Incompatible  with  ferric  and  silver 
salts,  potassium  chlorate  or  permanganate,  lead  acetate  or 
opium  in  solution.  (See  also  Reagents  [Part  IV].) 

Acid  Qallotannic.        See  Acid  Tannic. 

Acid   Hydriodic   Diluted,   Squibb  g.  s.  bottle,  Ib. 

3  1 .25  mil  ampuls,  2  in  bdx,  per  box 

Acidum  Hydriodicum  Dilution.  Contains  9.5  to  10.5  percent. 
HI.  Made  by  process  superior  to  official  one,  and  insuring  a 
much  cleaner  and  more  stable  product.  Colorless  or  pale-yellow, 
odorless  liquid;  sp.  gr.  about  1.100.  Miscible  with  water  and 
alcohol.  Alterative,  acting  like  potassium  iodide.  Average 
Dose:  8  minims  (0.5  mil  [Cc.]),  well  diluted,  after  meals. 
(See  also  Syrup.) 


SQUIBB'S  MATERIA  MEDICA  5 

Acid   Hydrobromic,  Squibb 

g.  s.  bottle,  Ib.          ;  J4  lb.          ;  oz. 

Highly  pure,  made  by  special  process,  and  adjusted  to  34  per- 
cent. HBr,  equivalent  to  just  half  the  bromine  strength  of 
potassium  bromide,  in  place  of  which  it  is  quite  generally  used. 
It  also  serves  for  making  official  diluted  hydrobromic  acid  by 
mixing  5  parts  of  it  with  12  parts  distilled  water.  Dose:  5  to 
10  minims  (0.3  to  0.6  mil  [Cc.]),  well  diluted.  Antidotes: 
magnesia  or  alkaline  carbonates.  (See  also  Reagents  [Part 
IV].) 

Acid  Hydrobromic  Diluted,  Squibb 

paraffin  s.  bottle,  lb.         ;  ]/4  lb.         ;  oz. 

Acidum  Hydrobromicum  Dilulum.  Contains  9.5  to  10.5  per- 
cent. HBr.  Colorless  liquid,  sp.  gr.  about  1.076.  Nervine. 
Average  Dose:  15  minims  (1  mil  [Cc.]).  This  acid  will  be 
sent  on  orders  for  hydrobromic  acid  when  no  strength  is  speci- 
fied. 

©  Acid  Hydrochloric,  Squibb 

g.  s.  bottle,  6  Ibs.,  per  lb.  ;  Ib.  ;  %  lb. 
So-called  "C.  P."  Acidum  Hydrochloricum ;  Concentrated  Mu- 
riatic Acid.  Contains  31  to  33  percent.  HC1.  An  exceptionally 
pure  quality.  Sp.  gr.  about  1.155.  Used  pharmaceutically 
and  technically.  Antidotes:  chalk,  magnesia;  emetics;  albumin 
and  demulcents.  (See  also  Reagents  [Part  IV].) 

©  ACID  HYDROCHLORIC  DILUTED. 

Acidum  Hydrochloricum  Dilulum.  Contains  9.5  to  10.5  per- 
cent. HC1.  Sp.  gr.  about  1 .049.  Digestive  Acid,  Antiseptic. 
Average  Dose:  15  minims  (1  mil  [Cc.]). 

0  Acid    Hydrocyanic    Diluted,    Squibb  ;  oz. 

Acidum  Hydrocyanicum  Dilutum;  Dilute  Prussic  (Cyanhydric) 
Acid.  Contains  1.9  to  2.1  percent.  HCN.  The  improved 
method  of  manufacture  gives  an  acid  which  is  not  very  prone 
to  decomposition.  But  however  made,  the  acid  is  liable  to 
•eventually  become  discolored,  and  is  then  unfit  for  use.  Anti- 
spasmodic,  Cough  Sedative;  Antipruritic  (only  on  unbroken 
skin),  in  1:8  to  16  lotions  or  ointments.  Average  Dose:  UAj 
minims  (0.1.  mil  [Cc.]).  Antidotes:  hydrogen  dioxide  freely 
by  mouth  and  subcutaneously,  or  arsenic  antidote  with  some 
iron  sulphate,  then  emetics;  ammonia  or  atropine;  brandy  later. 

Acid  Hydrofluoric  Reagent.         See  Reagents  (Part  IV). 


jf  difficulty  is  experienced  in  procuring  any  Squibb  product, 
in  the  original  packages  here  listed,  please  notify  us;  we 
shall  see  that  your  wants  are  met  promptly  and  satisfactorily. 


6  SQUIBB'S  MATERIA  MEDICA 

i 

Acid   Hypophosphorous,  Squibb 

g.  s.  bottle,  Ib.          ;  54  lb-          ;  oz. 

Acidum  Hypophosphorosum.  30  to  32  percent.  HPH2O2. 
Colorless,  odorless  liquid;  sp.  gr.  about  1.130;  miscible  with 
water.  Serves  for  preparation  of  diluted  acid. 

Acid    Hypophosphorous    Diluted,    Squibb 

g.  s.  bottle,  Ib.          ;  %  Ib.          ;  oz. 

Acldum  Hypophosphorosum  Dilulum.  9.5  to  10.5  percent,  abso- 
lute acid.  Used  as  Nerve  Tonic;  ingredient  of  compound 
hypophosphite  preparations.  Average  Dose :  8  minims  (0.5 
mil  [Cc.]).  Incompatible  with  iodine,  arsenical  salts,  cupric 
and  ferric  salts,  and  sulphuric  and  sulphurous  acids. 

Acid   Lactic,  Squibb  bottle,  Ib         ;  %  Ib.         ;  oz. 

Acidum  Lacticum.  High  quality.  85  to  90  percent.  CsHf.Os, 
as  against  75  percent,  in  previous  U.  S.  P.  Colorless  or  faintly 
yellow,  syrupy,  nearly  odorless  liquid;  acid  taste.  Freely 
miscible  with  water,  alcohol  or  ether;  insoluble  in  chloroform. 
Caustic  in  50  to  80  percent,  solution; Astringent  internally; 
also  Reagent.  Average  Dose:  30  minims  (2  mils  [Cc.]), 
well  diluted.  Readily  absorbs  moisture  on  exposure,  thereby 
becoming  weakened. 

ACID  METHYLENECITRYLSALICYLIC.    See  Novaspirin. 
Acid  Moiybdic  Reagent.        See  Reagents  (Part  IV). 
Acid   Muriatic.         See  Acid   Hydrochloric. 

0  Acid  Nitric,  Squibb     g.  s.  bottle,  7  Ibs.,  per  Ib.          ;  Ib.         ; 

;  ]A  Ib. 

Acidum  Nitricum;  so-called  "C.  P'."  Concentrated  Nitric 
Acid;  Aqua  Fortis.  67  to  69  percent.  HNOs-  An  especially 
pure  product.  Sp.  gr.  about  1.403.  Caustic.  Antidotes: 
magnesia,  chalk,  lime  water,  or  soap  and  water;  emetics;  oil, 
demulcents.  (See  also  Reagents  [Part  IV].) 

Acid  Nitrohydrochloric,  Squibb 

g.  s.  bottle,  Ib.          ;  %  Ib. 

Acidum  Nilrohydrochloricum ;  Aqua  Regia.  A  strong  aqueous 
solution  containing  hydrochloric  acid,  nitric  acid,  nitrosyl 
chloride  and  chlorine.  Yellow,  fuming,  very  corrosive  liquid. 
Caustic;  also  used  as  Hepatic  Stimulant.  Average  Dose:  3 
minims  (0.2  mil  [Cc.]),  well  diluted.  Antidotes:  magnesia, 
chalk,  lime  water,  or  soap  and  water;  emetics;  oil  and  de- 
mulcents. 

,  ACID  NITROHYDROCHLORIC  DILUTED. 

Acidum  Nilrohydrochloricum  Dilulum.  Two-ninths  strength 
of  preceding  article.  Us«d  in  biliary  calculi,  dyspepsia,  etc. 
Average  Dose:  15  minims  (1  mil  [Cc.]). 


SQUIBB'S  MATERIA  MEDICA  7 

Acid  Oleic,  Squibb  bottle,  Ib.        ;  |/2  lb-        ;  V*  Ib. 

Acidum  Olelcum ;  Elaic  Acid.  Obtained  from  fats. 
CisH34O;>.  Yellowish  or  brownish-yellow,  oily  liquid,  becom- 
ing darker  and  absorbing  oxygen  on  exposure.  Sp.  gr.  about 
0.895.  Soluble  in  alcohol,  chloroform  and  oils.  Because  of 
its  freedom  from  stearin  and  allied  fatty  acids,  it  produces 
oleates  which  are  more  rapidly  and  completely  absorbed  than 
ordinary  oleates,  and  are  free  from  that  greasy  property  which 
is  so  objectionable.  Also  Reagent. 

Acid  Ortho=Hydroxybenzoic.       See  Acid  Salicylic. 

Acid   Oxalic,   Squibb  bottle,  Ib.         ;  %  Ib. 

H^CoO.j^HoO.  Of  very  high  purity;  specially  recrystallized, 
free  from  calcium  sulphate  and  chlorides.  Transparent  gran- 
ules; very  acid  taste.  Soluble  in  water  or  alcohol.  Emmen- 
agogue,  Sedative.  Dose:  Yi  to  1  grain  (0.03  to  0.065  Gm.), 
in  sweetened  water.  Antidotes:  calcium  saccharate,  syrup  lime, 
lime  water,  or  magnesia,  then  emetics.  (See  also  Reagents 
[Part  IV].) 

©  ACID  PHENYLCINCHONINIC. 

AciJum  Phenylcinchor.inicum  ;  Phenyl-quinoline-carboxylic 
Acid;  Atophan.  White  or  yellowish  white,  crystalline, 
bitter  powder.  Insoluble  in  water;  slightly  soluble  in  alcohol, 
readily  in  alkali  solutions.  Uric-acid  Eliminant.  Average  Dose : 
8  grains  (0.5  Gm.),  with  copious  draught  of  water,  liberal 
doses  of  sodium  bicarbonate  being  taken  simultaneously. 

Acid   Phosphoric,  Squibb  g.  s.  bottle,  Ib.         ;  %  Ib. 

Acidum  Phosphoricum ;  Ortho-phosphoric  Acid.  Contains  85 
to  88  percent.  HsPO.^.  Best  syrupy  acid.  Sp.  gr.  about 
1.72.  Miscible  with  all  proportions  of  water  or  alcohol. 
Antidotes:  alkalies  and  their  carbonates  and  bicarbonates.  (See 
also  Reagents  [Part  IV].) 

ACID    PHOSPHORIC   DILUTED. 

Acidum  Phosphoricum  Dilulum.  Contains  9.5  to  10.5  per- 
cent. HsPO-i.  Digestive,  Refrigerant.  Average  Dose :  30 
minims'  (2  mils  [Cc.]),  diluted.  Incompatible  with  ferric 
chloride,  lead  acetate,  solutions  soluble  iron  phosphate  and 
pyrophosphate,  and  silver  nitrate. 

Acid  Phosphoric   Glacial,   Squibb 

(Sticks)  bottle,  Ib.          ;  !4  Ib.          ;  oz. 

Acid  Metaphosphoric.  HPOs.  Transparent,  highly  deliques- 
cent solid.  Soluble  in  water,  alcohol.  Urine-albumin  test; 
also  used  pharmaceutically  and  technically. 


The  Squibb  products  are  recognized  everywhere  as  the  Quality 
Standard.  They  are  of  uniform  purity  and  strength,  hence 
theraupeutically  dependable.  When  ordering  or  prescribing  medi- 
cinal products,  you  will  do  well  always  to  specify  SQUIBB'S. 


8  SQUIBB'S  MATERIA  MEDICA 

Acid  Phosphotungstic  Reagent.        See  Reagents  (Part  IV). 

ACID    PICRIC.      See   Trinitrophenol. 

Acid    Prussic    Diluted.       See    Acid    Hydrocyanic    Diluted. 

Acid   Pyrogallic.     See  Pyrogallol. 

©  Acid  Salicylic,  Squibb 

*  Crystals  carton,  Ib.          ;  '/4  N>.         ;  oz. 

Powdered  carton,  Ib.         ;  14  Ib.         ;  oz. 

Acidum  Salicylicum;  Orthohydroxybenzoic  Acid.  CjHgOs. 
Recrystallized.  A  high-grade  medicinal  acid.  I  Gm.  dissolves 
in  460  mils  (Cc.)  water,  2.7  alcohol,  42  chloroform,  3  ether. 
Aqueous  solubility  increased  by  borax,  potassium  citrate,  sodium 
phosphate  or  sulphite.  Antirheumatic ;  Antiseptic,  Germicide, 
Keratolytic;  also  Reagent.  Average  Dose:  12  grains  (0.75 
Gm.).  Incompatible  with  iron  salts,  spirit  nitrous  ether,  lead 
acetate,  potassium  iodide,  and  quinine  salts,  in  solution. 

Acid    Salicylic   Natural,    Squibb 

carton,  Ib.          ;  |/4  Ib.         oz. 

The  true,  natural  acid;  from  oil  betula.  Colorless  crystals, 
with  characteristic  odor.  Preferred  by  many  physicians  to,  the 
synthetic  acid,  but,  ace.  to  Council  on  P.  &  C.  of  A.  M.  A., 
not  superior  to  latter.  Dose :  same  as  preceding. 

Acid  Stearic,  Squibb  tin,  Ib. 

Acidum  Stearicum.     CisHseOo.     From  tallow  and  other   fats.- 
Especially    adapted    for    the    manufacture    of    stearates.      Hard, 
white,    nearly   odorless,   tasteless   solid.      1    Gm.   dissolves   in   21 
mils    (Cc.)    alcohol,    2    chloroform,    3    ether;    almost    insoluble 
in  water.     Uses  technical  and  pharmaceutical;    also  Reagent. 

Acid  Sulphuric,  Squibb 

g.  s.  bottle,  9  Ibs.  Ib.          ;  Ib.          ;  !4  Ib. 

Acidum  Sulphuricum ;  Concentrated,  so-called  "C.  P."  Sul- 
phuric Acid;  Oil  Vitriol.  Contains  93  to  95  percent.  H^.SO4. 
Sp.  gr.  about  1.83.  Caustic,  oily  liquid  miscible  with  water 
and  alcohol  with  evolution  of  much  heat.  Antidotes:  chalk, 
magnesia  or  albumin.  (See  also  Reagents  [Part  IV].) 

Acid  Sulphuric  Aromatic,   Squibb 

g.  s.  bottle,  Ib.  ;  J4  Ib. 

Acidum  Sulphuricum  Aromalicum;  Elixir  of  Vitriol.  Contains 
19  to  21  per  cent.  HjSO},  with  tincture  ginger,  oil  cinnamon 
and  alcohol.  Intestinal  Astringent,  Stomachic;  good  solvent  for 
quinine  sulphate.  Average  Dose:  15  minims  (1  mil  [Cc.]), 
well  diluted. 

ACID  SULPHURIC  Diluted. 

Acidum  Sulphuricum  Diluium.  Contains  9.5  to  10.5  percent. 
H->SO4.  Sp.  gr.  about  1.067.  Average  Dose:  15  minims  (1 
mil  [Cc.]). 


SQUIBB'S  MATERIA  MEDICA  9 

Acid  Sulphurous,  Squibb  g.  s.  bottle,  Ib.         ;  |4  N>. 

Acldum  Sulphurosum,  U.  S.  P.  VHIth  Rev.;  dropped  from 
the  present  pharmacopoeia.  Contains  about  6.5  percent. 
SOo.  Exceptionally  free  from  sulphuric  acid.  Colorless 
liquid;  odor  of  burning  sulphur,  and  sulphurous  taste.  Anti- 
septic and  Antizymotic.  Average  Dose:  30  minims  (2  mils 
[Cc.]),  well  diluted.  (See  also  Reagents  [Part  IV].) 

©  Acid  Tannic,  Squibb  cajton,  Ib.  ;  '/*tt>-  ;  oz. 
AciJum  Tannicum;  Gallotannio  Acid;  Tannin.  HCi^HgOg. 
A  specially  repurified,  medicinal  product;  not  the  regular  mar- 
ket grade.  Bulky  and  light  colored.  1  Gm.  dissolves  in  1  mil 
(Cc.)  glycerin;  very  soluble  in  water,  alcohol;  almost  insoluble 
in  ether,  chloroform.  Prone  to  darken  on  exposure.  Astrin- 
gent, Styptic;  Antidote  for  certain  alkaloidal  and  metal- 
lic salts.  Used  locally  in  hemorrhages,  pure;  in  1  to  10 
percent,  solutions  as  mouth  wash,  injections,  lotions,  collodion, 
etc.;  internally,  in  diarrhea,  night-sweats,  diabetes,  etc.  Average 
Dose:  8  grains  (0.5  Gm.).  Incompatible  with  salts  of  antimony, 
copper,  iron,  lead,  mercury  and  silver;  with  alkaloids,  albumin, 
gelatin,  iodine,  iodoform;  with  permanganates,  chlorates  and 
other  oxidizers.  (See  also  Glycerite;  Troches  [Part  II]; 
Reagents  [Part  IV].) 

Acid  Tartaric,  Squibb 

(Powdered)  carton,  Ib.         ;  %  Ib. 

AciJum  Tartaricum;  Dioxysuccinic  Acid.  Contains  not  less 
than  99.5  percent.  HoCiHiOe.  White  powder.  1  Gm.  dis- 
solves in  0.75  mil  (Cc.)  water,  3.3  mils  alcohol,  4  glycerin; 
slightly  soluble  in  ether;  almost  insoluble  in  chloroform.  Re- 
frigerant and  Antiscorbutic.  Average  Dose  t  8  grains  (0.5 
Gm.).  Incompatible  with  salts  of  calcium,  lead,  and  mercury. 
(See  also  Reagents  [Part  IV].) 

Acid  Trichloracetic,  Squibb  g.  s.    bottle,  oz. 

AciJum  Trichloraceticum.  HC2CI3O2.  Colorless,  deliques- 
cent crystals;  pungent,  suffocating  odor.  1  Gm.  dissolves  in  0.1 
mil  (Cc.)  water;  very  soluble1  in  alcohol  or  ether.  Caustic, 
Styptic,  Astringent;  in  nasopharyngeal  diseases,  warts,  etc. 
Applied  pure  or  in  concentrated  solution,  as  caustic;  in  1  to  3 
percent,  solution,  as  astringent.  Used  also  as  test  for  albumin. 

ACIDOL. 

Betaine  Hydrochloride.  Colorless  crystals;  23.8  percent. 
HC1.  Soluble  freely  in  water.  Substitute  for  diluted  hydro- 
chloric acid  as  Digestive.  Dose:  8  grains  (0.5  Gm.),  in  water. 


Since  we  make  only  one  quality  of  each  product,  that  best 
suited  to  the  purposes  intended,  the  specification  "Squibb's" 
is  not  open  to  various  interpretations,  but  has  a  plain,  positive 
meaning.  When  ordering  or  prescribing,  specify  SQUIBB'S. 


\ 
10          SQUIBB'S  MATERIA  MEDICA 

0  Aconite  Root,  Squibb 

Ground  for  Percolation  tin,  lb. 

Aconilum;  Monkshood;  Wolfsbane.  Best  quality,  dried  root 
of  Aconitum  napellus  (Fam.  Ranunculacea) .  U.  S.  P.  re- 
quires not  less  than  0.5  percent,  ether-soluble  alkaloids.  Physi- 
ologically assayed  according  to  U.  S.  P.  IXth  Rev.  and  found 
to  yield  official  preparations  of  not  less  than  standard  strength. 
Circulatory  Sedative,  Sudorific,  Antineuralgic.  Average  Dose: 
1/2  grain  (0.03  Gm.).  Antidotes:  emetics;  atropine,  digitalis  or 
ammonia;  small  frequent  doses  of  stimulants;  artificial  respira- 
tion. (See  also  Extract;  Fluidextract;  Liniment;  Tincture.) 

Aconitine  Crystals,  Squibb  '/8-°z.  ;15-gr.  vial 
Aconitina.  Cs-jr-^OnN.  Crystalline  alkaloid  from  aconite 
root.  Colorless  or  white,  odorless  crystals.  1  Gm.  dissolves 
in  28  mils  (Cc.)  alcohol,  about  65  ether;  very  slightly  soluble 
in  water.  Antineuralgic,  Sudorific,  Circulatory  Sedative. 
Average  Dose:  V-ioo  8ra'n  (0.00015  Gm.),  in  pills  or  tablets. 
Used  externally  in  1  :2000  to  500  ointments,  or  2  percent,  oleate, 
in  neuralgias.  Antidotes :  stimulants,  atropine,  digitalis  or  am- 
monia. Dangerous  to  use  on  abraded  surfaces.  (See  also 
Tablets  [Part  II].) 

ADALIN. 

Bromdiethylacelylcarbamide.  Nearly  colorless,  odorless  pow- 
der. Readily  soluble  in  alcohol,  ether,  chloroform;  sparingly 
in  water.  Nerve  Sedative,  mild  Hypnotic.  Dose:  5  to  15 
grains  (0.3  to  1  Gm.). 

Adeps  Lanae.        See  Wool-Fat. 

ADONIS. 

Adonis,  N.  F.;  Pheasant's  F_ye.  Dried,  overground  portion  of 
Adonis  vernalix  (Fam.  Ranunculacece) .  Cardiac  Tonic  of  digi- 
talis group,  but  ace.  to  Council  on  P.  &  C.  of  A.  M.  A. 
of  unreliable  activity.  Average  Dose:  2  grains  (0.13  Gm.). 

\DRENALIN.     See  under  Epinephrine. 

ACAR. 

A  gar;  Agar-Agar.  Dried  mucilaginous  substance  from  marine 
algae  growing  along  eastern  coast  of  Asia.  Odorless,  tasteless 
shreds,  or  granular  powder.  Insoluble  in  cold  water;  slowly 
soluble  in  hot  water,  forming  jelly  when  cool.  Culture  medium; 
mechanical  Laxative.  Used  in  chronic  constipation;  passes 
through  intestines  almost  unchanged.  Average  Dose :  1  50  grains 
(10  Gm.). 

AGARIC. 

Agaricus,  N.  F.;  White  Agaric;  Larch  Agaric.  Dried  fruit 
body  of  fungus  Polyporus  officinalis  (Fam.  Po/pporace<z). 
deprived  of  its  ou«ter  rind.  Used  as  Antihydrotic.  Average 
Dose:  10  grains  (0.65  Gm.). 


SQUIBB'S  MATERIA  MEDICA          11 

AGURIN. 

Theobromine-S odium  Acetate.  White,  hygroscopic,  alkaline 
powder.  60  percent,  theobromine.  Soluble  freely  in  water; 
decomposed  by  acids  and  carbon  dioxide.  Diuretic.  Dose : 
8  to  15  grains  (0.5  to  1  Gm.). 

AIKEN'S  TONIC  PILLS.     S«e  Pills  Iron,  Quinine,  Strychnine  and 
Arsenic,    Mild. 

AlROL. 

Airoform;  Bismuth  Oxyiodogallate.  CeH^OH^CGV 
Bi(OH)I.  Grayish-green,  fine,  odorless,  insoluble  powder; 
20  percent,  iodine.  Vulnerary,  Antigonorrheic.  Incompatible 
with  water  and  calomel. 

ALBARCIN. 

Compound  of  silver  nitrate  with  gelatose.  Coarse,  yellow  pow- 
der, readily  soluble  in  water;  contains  about  15  percent,  silver. 
Astringent  and  Bactericide,  like  silver  nitrate. 

0  ALCOHOL. 

Alcohol.  92.3  percent,  by  weight  or  94.9  percent,  by  volume 
of  C2H3.OH.  Sp.  gr.  not  above  0.816  at  15.56°  C.  Stimulant 
internally;  Refrigerant,  Rubefacient,  Astringent  and  Antiseptic 
topically.  Dose:  1  to  4  fluidrachms  (4  to  16  mils  [Cc.]). 
Incompatible  with  acacia,  albumin,  bromine,  chromic  acid,  per- 
manganates. 

Alcohol   Dehydrated   (Absolute),   Squibb 

bottle,  gal.  (6%  Ibs.),  per  Ib.  ;  Ib.  ;  %  Ib. 

Alcohol  Dehydraium;  Anhydrous  Alcohol.  C2H5-OH.  The 
U.  S.  P.  permits  1  percent,  water;  our  product  contains  only 
0.2  percent,  and  thus  runs  about  99.8  percent,  strength,  sp.  gr. 
0.7945  at  15.56°  C.,  contains  no  empyreumatic  impurities,  and 
complies  with  all  official  tests.  However,  when  it  is  kept  for 
any  length  of  time  in  cork-stoppered  bottles,  it  is  apt  to  show 
slight  traces  of  discoloration  when  the  sulphuric  acid  test  is 
applied,  which,  however,  if  within  the  limits  of  merely  brown- 
ing the  acid,  may  be  regarded  as  not  seriously  objectionable. 
(See  also  Reagents  [Part  IV].) 

ALCOHOL  DILUTED. 

Alcohol  Dilutum.  41  to  42  percent,  by  weight  or  48.4  to  49.5 
volume  percent.  CoHs-OH. 

Alcohol   Methyl,   Reagent.  See  Reagents   (Part  IV). 


The  founder  of  the  House  of  Squibb,  Dr.  Edward  R.  Squibb, 
not  only  had  high  ideals,  but  lived  and  labored  for  them;  and, 
in  the  words  of  William  Miller  Bartlett,  "the  House  of  Squibb 
stands  today  as  a  living  monument  to  the  honor,  integrity,  zeal 
and  devotion  of  its  founder." 


12          SQUIBB'S  MATERIA  MEDICA 

ALETRIS. 

Aletris,  N.  F.;  Unicorn  Root;  Star  Grass.  Dried  rhizome  and 
root  of  Aletris  farinosa  (Fam.  Liliacece).  Simple  Bitter, 
without  advantage  over  gentian.  Largely  used  in  "  female 
remedies,"  but,  ace.  to  Council  on  P.  &  C.,  without  good 
evidence  of  value.  Average  Dose :  30  grains  (2  Cm.).  (See 
also  Fluidextract.) 

Allspice,  Squibb        *  Whole  tin,  Ib. 

Powdered  tin,  Ib. 

sprinkler-top  tins,  4  oz.,  per  doz. 

2  ozs.,  per  doz.          ;  1  oz.,  per  doz. 

Pimento,  N.  F.;  Pimento.  Dried,  nearly  ripe  fruit  of 
Pimenla  officinalis  (Fam.  Mpr/acete).  Derived  mostly  from 
Jamaica.  Collected  just  before  the  berries  become  ripe  and 
carefully  dried  in  the  sun.  Its  odor  resembles  a  mixture  of  cin- 
namon, nutmeg  and  cloves.  Allspice  should  contain  from  3  to  4 
percent,  of  oil,  upon  which  its  virtue  chiefly  rests.  Condiment, 
Aromatict  Stomachic.  Average  Dose:  15  grains  (1  Gm.). 

ALLIUM.        See   Garlic. 

Allyl  Sulphocarbamide.       See  Thiosinamine. 

ALMOND,  SWEET. 

Amygdala  Dulcis.  Dried  ripe  seeds  of  Prunus  amygdalus 
Julcis  (Fam.  Rosaceae).  Demulcent,  Nutrient;  also  used 
pharmaceutically. 

0  ALOES. 

Aloe.  Inspissated  juice  of  leaves  of  Aloe  Perry/,  A.  vera  or 
A.  ferox,  respectively  Socotrine,  Curasao  or  Cape  Aloes: 
Moderately  active  Cathartic,  acting  mostly  on  the  large  intes- 
tine. Average  Dose:  4  grains  (0.25  Gm.). 

Aloes  Purified,  Squibb 

Ground  for  Percolation  tin,  Ib. 

*Powdered  tin.  Ib.         ;  ^i  Ib. 

Aloes  Purificata,  U.  S.  P.  VHIth  Rev.  Dropped  from  new 
pharmacopoeia.  From  best  quality  Curacao  aloes.  Dull- 
brown  or  reddish -brown  powder,  almost  completely  soluble  in 
alcohol  also  soluble  in  alkalies.  Cathartic;  acts  mostly  on 
large  intestine.  Average  Dose:  4  grains  (0.25  Gm.). 

0  Aloin,    Squibb  bottle,  Ib.          ;  %  Ib.          ;  oz. 

Aloinum.  Pentoside  or  mixture  of  pentosid-es  from  aloes.  Yel- 
low to  yellowish-brown,  very  bitter  powder;  faint  odor.  Sol- 
uble in  water,  alcohol,  acetone,  ammonia  water  and  alkali  solu- 
tions; slightly  soluble  in  ether.  Acts  like  aloes.  Average  Dose; 
%  grain  (0.015  Gm.). 


SQUIBB'S  MATERIA  MEDICA          13 

ALTHAEA   LEAVES. 

Althaa  Folia,  N.  F. ;  Marsh  Mallow  Leaves.  Dried  leaves  of 
Althaea  officinalis  (Fam.  Malvacea).  Emollient,  Demulcent; 
mostly  used  as  cataplasm. 

Althaea   Root    Powdered,   Squibb  tin,  lb. 

Althaea;  Marsh  Mallow  Root.  Dried  root  of  Allhcea  offi- 
cinalis (Fam.  Mahaced),  deprived  of  brown,  corky  layer  and 
small  roots.  Very  rich  in  mucilaginous  principle.  Preserve  in 
tightly-closed  containers,  adding  a  few  drops  chloroform  from 
time  to  time  to  prevent  insects.  Emollient,  Demulcent. 

©  Alum,  Squibb        *  Granulated  carton,  lb. 

Powdered  carton,  lb.         ;  ]/$  lb. 

Alumen ;  Ammonium  Alum;  Aluminum  and  Ammonium  Sul- 
phate. A1NH4  (SO4)2. 1 2H2O.  Soluble  in  water;  freely  sol- 
uble in  glycerin;  insoluble  in  alcohol.  Astringent,  Styptic, 
Emetic;  in  night-sweats,  diarrhea,  hemorrhage,  epistaxis, 
wounds,  etc.  Average  Dose :  8  grains  (0.5  Gm.) ;  as  emetic, 
a  teaspoonful  is  usually  given.  Incompatible  with  borax,  car- 
bonates, galls,  kino,  lead  acetate,  magnesia,  mercury  salts,  phos- 
phates and  tartaric  acid.  NOTE:  The  present  U.  S.  P.  recog- 
nizes both  ammonium  alum  and  potassium  alum;  the  latter 
is  not  obtainable  at  this  time. 

©  Alum  Exsiccated,  Squibb  tin,  lb.        ;  %  lb. 

Alumen  Exsiccatum.  Preceding  article  rendered  anhydrous  by 
drying.  White,  hygroscopic  powder;  astringent  taste. 
Escharotic,  Astringent,  Vulnerary.  Keep  well  stoppered,  in 
dry  place.  (See  also  Powder  Alum  Compound.) 

Alum  Powder  Compound.     See   Powder   Alum  Compound. 

Alum,  Chrome,  Squibb  carton,  lb.         ;  %  lb. 

Chromium  and  Potassium  Sulphate.  CrK^SO^i-JZHoO. 
Dark-violet,  large  crystals.  Soluble  in  about  5  parts  water. 
Basis  for  manufacture  of  pigments  (for  dyeing,  calico-print- 
ing, etc.). 

©  Aluminum  Acetate,  Squibb         bottle,  lb.         ;  %  lb. 

Basic  Aluminum  Acetate.  Fine,  white  powder;  slight  as- 
tringent, acidulous  taste.  Well-nigh  insoluble  in  water  or  al- 
cohol. External  and  Intestinal  Astringent.  Dose:  5  to  10 
grains  (0.3  to  0.65  Gm.).  (See  also  Solution  Aluminum  Ace- 
tate.) 


The  Squibb  Ideals  have  taken  concrete  form  in  the  Squibb 
Products;  these  are  universally  recognized  as  standards  of 
uniform  Purity  and  Efficacy,  that  is,  general  Excellence  and 
Reliability.  Specify  SQUIBB'S  when  prescribing  or  orderingc 


14          SQUIBB'S  MATERIA  MEDICA 

ALUMINUM  CHLORIDE. 

Alumini  Chloridum,  N.  F.  AlCls^H-A  White  or  yellow- 
ish-while, nearly  odorless  powder;  sweetish,  astringent  taste.  1 
Gm.  dissolves  in  about  0.5  mil  (Cc.)  water,  4  alcohol;  solu- 
ble in  glycerin.  Antiseptic,  Astringent;  without  advantage 
over  alum.  Average  Dose:  5  grains  (0.3  Gm.). 

ALUMINUM  HYDROXIDE. 

Alumini  Hydroxidum ;  Precipitated  Aluminum  Oxide.  Al- 
(OH)3.  White,  bulky,  odorless,  tasteless,  amorphous  powder. 
Insoluble  in  water,  alcohol,  etc.  Astringent,  Desiccant  Dermic. 

Aluminum  Nitrate  Reagent.       See  Reagents  (Part  IV). 

Aluminum  Sulphate,  Squibb 

"Granulated  or  Powdered  carton,  lb. 

Alumini  Sulphas,  N.  F.  Al2(SO4)3.16HoO.  White  granules 
or  powder;  sweetish,  astringent  taste.  1  Gm.  dissolves  (not 
clearJy)  in  about  1  mil  (Cc.)  water;  insoluble  in  alcohol. 
Antiseptic,  Astringent;  on  ulcers,  enlarged  tonsils  in  en- 
dometritis,  etc.;  usually  applied  in  1  to  5  percent,  solutions,  oc- 
casionally in  concentrated  solution.  Also  Reagent. 

Aluminum=Ammonium  Sulphate.     See  Alum. 

Aluminum=Potassium  Sulphate  Reagent.       See  Reagents 
(Part  IV). 

ALUMNOL. 

Aluminum  Betanaphtholsulphonate.  Al(CioH(i[OH]SO3)3. 
White,  hygroscopic,  bitter  powder.  Soluble  in  about  1 .5  parts 
water;  easily  in  glycerin,  sparingly  in  alcohol.  Astringent, 
Antiseptic ;  in  0.5  to  3  percent,  solutions. 

ALYPIN. 

White,  hygroscopic,  bitter  powder.  Soluble  very  freely  in 
water,  easily  in  alcohol.  Local  Anesthetic;  in  10  percent,  solu- 
tion topically,  1  to  4  percent,  hypodermically. 

AMINOFORM.     Brand    of    Hexamethylenamine. 

0  Ammonia  Water  (10r/f  =16°  Be.),  Squibb 

g.  s.  bottle,  lb., 

Aqua  Ammonia;  Liquor  Ammoniae;  Spirit  of  Hartshorn.  10 
percent.  NH?,.  Sp.  gr.  about  0.958.  Local  Irritant  and  Ant- 
acid, in  liniments;  fugacious  indirect  Circulatory  and  Respira- 
tory Stimulant,  internally  or  hypodermically;  antidote  in 
chlorine  poisoning,  by  inhalation;  also  Reagent.  Average 
Dose:  15  minims  (1  mil  [Cc.]).  Incompatible  with  chlorine 
water,  iodine,,  alkaloidal  salts,  acids,  etc.  Liable  to  deteriorate 
on  keeping. 


SQUIBB'S  MATERIA  MEDICA          15 

Ammonia  Water  Stronger  (28</c-26°  Be.),  Squibb 

g.  s.  bottle,  rb., 

Aqua  Ammonia  Fortior;  Concentrated  or  Stronger  Ammonia. 
28  percent.  NHs-  Uses  chiefly  pharmaceutical,  chemical  and 
technical.  Antidotes:  vinegar;  vapor  of  acetic  acid  or  chlorine 
water  by  inhalation.  NOTE:  Should  be  handled  with  extreme 
caution,  lest  an  accident  occur.  In  warm  weather  the  bottles 
should  preferably  be  placed  on  ice  for  a  while,  before  with- 
drawing stopper.  (See  also  Spirit;  Reagents  [Part  IV]). 

Ammonio=FormaIdehyde.     See  Hexamethylenamine. 

Ammonium   Benzoate,    Squibb 

bottle,  Ib.         ;  %  Ib.          ;  oz. 

Ammonii  Benzoas.  From  Synthetic  Benzoic  Acid.  NH^G?- 
HjOo.  White  laminae  or  powder;  saline,  bitter,  acrid  taste. 
1  Gm.  dissolves  in  10  mils  (Cc.)  water,  35.5  alcohol,  8  gly- 
cerin. Mild  Antiseptic  and  Diuretic,  like  sodium  benzoate 
but  more  irritant;  also  Reagent.  Average  Dose:  15  grains  (1 
Gm.).  Incompatible  with  ferric  salts. 

Ammonium  Benzoate  from  Natural  (True)  Acid,  Squibb 

bottle,  Ib.          ;  %\b.-        ;  oz. 

Ammonium  Bromide,  Squibb          bottle,  Ib.         ;  1/4  Ib. 
Ammonii  Bromidum.      NF^Br.     White,    odorless   granules,   of 
pungent,  saline  taste.      1   Gm.  dissolves  in  1.3  mils   (Cc.)  water, 
12    alcohol.      Nerve    Sedative.      Average    Dose :    15    grains    (1 
Gm.).     Incompatible  with,  alkaloidal,  mercuric  and  silver  salts. 

0  Ammonium  Carbonate,  Squibb 

(Cubes)  bottle,  Ib.          ;  |4  Ib. 

Ammonii  Carbonas;  Hartshorn;  Volatile  Salt;  Volatile  Alkali. 
Mixture  of  acid  ammonium  carbonate,  NH-tHCOs,  and  am- 
monium carbamate,  Nr-^NH^COo.  The  widely  known  Squibb 
article  which  has  deservedly  won  high  reputation  for  its  ex- 
ceptional quality,  high  strength  and  reliability.  Colorless, 
translucent,  and  has  but  a  slight  coating  of  bicarbonate  on 
the  surface.  It  is  of  full  U.  S..  P.  strength,  assaying  at  time 
of  bottling  about  32  percent,  ammonia  gas.  Intended  espe- 
cially for  medicinal  use,  and  peculiarly  adapted  to  pre- 
scription work  and  for  making  aromatic  spirit  of  ammonia 
or  solution  of  ammonium  acetate.  1  Gm.  dissolves  slowly  in  4 
mils  (Cc.)  water,  A  glycerin;  partly  soluble  in  alcohol;  de- 
composed by  hot  water.  Cardiac  Stimulant  and  Expectorant. 
Average  Dose:  5  grains  (0.3  Gm.).  Incompatible  with  salts 
of  alkaloids,  acids  and  acid  salts  or  syrups,  calomel  and 
tartar  emetic.  Keep  well  stoppered,  in  a' cool  place;  on  ex- 
posure it  loses  ammonia.  A  piece  of  cotton  placed  into  a 
slit  in  bottom  of  cork  and  kept  moist  with  stronger  ammonia 
water  will  retard  change.  (See  also  Reagents  [Part  IV].) 

The  Squibb  Label  on  a  package  is  a  positive  guaranty  for  the 
uniform  Purity  and  Reliability  of  the  product.  We  make  only 
ONE  quality:  the  SQUIBB  quality;  and  our  prices  are  as  low 
as  they  can  be  made  for  that  quality.  Specify  SQUIBB'S. 


16         SQUIBB'S  MATERIA  MEDICA 

0  Ammonium  Chloride,  Squibb 

(Granulated)  carton,  lb.         ;  V4  Ib. 

Ammonil  ChloriJum;  Ammonium  Muriate;  Pure  Sal  Ammo- 
niac. NH-jCl.  High  quality;  prepared  from  refined  sal  am- 
moniac by  recrystallizing;  above  U.  S.  P.  requirement  of  99.5 
per  cent,  purity.  1  Gm.  dissolves  in  2.6  mils  (Cc.)  water,  100 
alcohol,  8  glycerin.  Liquefying  Expectorant,  Alterative;  in 
bronchial  affections,  glandular  enlargements,  dysmenorrhea,  etc. 
Average  Dose:  5  grains  (0.3  Gm.).  Incompatible  with  al- 
kaline hydroxides  and  carbonates,  soluble  lead  and  silver  salts. 
(See  also  Reagents  [Part  IV];  Tablets,  Troches,  [Part  II].) 

Ammonium  Chromate  Reagent.     See  Reagents  (Part  IV). 

Ammonium  Citrate,  Squibb 

bottle,  lb.          ;  14  lb.          ;  oz. 

(NH-j^CcHsGV  Granular,  deliquescent;  very  soluble  in 
water.  Diaphoretic,  Refrigerant;  also  Reagent.  Dose:  15 
grains  (1  Gm.).  Keep  well-stoppered. 

Ammonium  Hypophosphite,  Squibb 

bottle,  lb.          ;  J4  lb.          ;  oz. 

Ammonli  f/ppop/iosp/ii's,  N.  F.  NP^PHoOo.  White,  odor- 
less, scaly  crystals.  1  Gm.  dissolves  in  1  mil  (Cc.)  water,  20 
mils  alcohol.  Used  as  Alterative  and  Anticatarrhal.  Average 
Dose:  5  grains  (0.3  Gm.).  Keep  from  light  and  air;  darkens 

Ammonium  Iodide,  Squibb 

bottle,  lb.          ;  %  lb.          ;  oz. 

Ammonii  lodiJum.  NH-jI.  White  or  nearly  white,  granular, 
hygroscopic  powder;  saline  taste.  I  Gm.  dissolves  in  0.6  mil 
(Cc.)  water,  3.7  mils  alcohol,  1.5  glycerin.  Saline  Expec- 
torant, Alterative;  more  irritant  than  other  iodides.  Average 
Dose:  5  grains  (0.3  Gm.).  Keep  from  light  and  air;  darkens 
on  exposure.  A  deeply  colored  salt  should  not  be  dispensed. 

Ammonium    Molybdate.         See  Reagents   (Part  IV). 
Ammonium    Muriate.        See  Ammonium  Chloride. 
Ammonium  Nitrate  Reagent.       See  Reagents  (Part  IV). 
Ammonium  Oxalate  Reagent.        See  Reagents  (Part  IV). 

Ammonium  Persulphate  Reagent.       See     Reagents     (Part 
IV). 

Ammonium  Phosphate,  Squibb       bottle,  lb.         ;  %  Ib. 

Ammonii  Phosphas,  N.  F.;  Diammonium  Ortho-phosphate. 
(NHi)-_>HPO|.  Colorless,  odorless  crystals;  saline  taste. 
1  Gm.  dissolves  in  about  4  mils  (Cc.)  water;  insoluble  in  alco- 
hol. Similar  in  action  to  sodium  phosphate,  but  used  mainly 
as  Antirheumatic  and  Alterative.  Average  Dose :  5  grain? 
(03  Gm.).  (See  also  Reagents  [Part  IV].) 


SQUIBB'S  MATERIA  MEDICA          17 

Ammonium  Salicylate,  Squibb 

bottle,  Ib.         ;  '/$  lb.          ;  oz. 

Ammonii  Salicylas.  NH+CiHzOs.  White,  odorless,  crystal- 
line powder;  faintly  saline,  bitter  taste.  1  Gm.  dissolves  in 
1  mil  (Cc.)  water,  3  mils  alcohol.  Antirheumatic,  Analgesic, 
Expectorant.  Average  Dose:  8  grains  (0.5  Gm.). 

Ammonium  Sulphate  Reagent.    See  Reagents  (Part  IV). 

Ammonium  Sulphocyanate  Reagent.      See  Reagents  (Part 
IV). 

AMMONIUM  SULPHOICHTHYOLATE.     See  Ichthyol. 
Ammonium  Valerate,  Squibb      g.s.  bottle,  %  lb.        ;  oz. 

Ammonii    Valeras;    Ammonium    Valerianate.      NHiCsHgOo. 

White   plates;    valerian    odor;    sharp,    sweetish    taste.      1    Gm. 

dissolves  in  0.3  mil   (Cc.)  water,  0.6  alcohol;    soluble  in  ether. 

Nerve   Sedative   in   hysteria.     Average    Dose:     8   grains    (0.5 

Gm.). 

SQUIBB'S  AMPULS 

of  Sterile  Solutions  for  Hypodermic  or  Intramuscular 
Injection 

In  response  to  a  request  from  many  physicians  we  have  added 
to  our  list  a  number  of  sterile  solutions  for  hypodermic  or  intra- 
muscular injection,  and  will  add  others  as  the  demand  arises. 
They  are  put  up  in  hermetically  sealed  tubules  or  ampuls.  For 
use,  sterilize  the  syringe  and  the  needle,  break  off  the  stem 
of  the  ampul  at  the  file  mark  on  the  neck,  turn  the  ampul  up- 
side down,  introduce  the  needle,  withdraw  the  contents  and 
inject. 

Caffeine  Sodio=SalicyIate 

Contains  about  50  percent,  caffeine,  and  is  soluble  in  2  parts 
water,  hence  serviceable  for  hypodermic  use  (chiefly  in  acute 
articular  rheumatism  complicated  with  heart  disease,  and  in 
threatened  collapse  in  pneumonia).  O.I  Gm.  (1]/2  gr-)  in 
1  Cc.  (mil)  ampuls,  box  of  1  dozen. 

Camphor 

Is  employed  subcutaneously  as  a  stimulant  in  sudden  depression 
and  collapse  as  seen  in  infectious  diseases  and.  other  exhausting 
affections  and  after  operations.     The  ordinary  dose  is  8   grains 
per  injection;   however,  in  pneumonia  larger  doses  are  used — up 
to  30   grains   per   day,   smaller   quantities   having   proved   of   no 
avail   here.      Supplies    as    solutions    in    expressed    oil    almond: 
0.1    Gm.    (1J/2    grs.)    in    1    Cc.    ampuls,    box    of    1    dozen, 
0.2    Gm.    (3        grs.)    in    1    Cc.    ampuls,   box    of    1    dozen. 


This  house  supplies  only  one  quality  of  each  product:  that  best 
suited  to  the  purposes  intended.  •  The  specification  "Squibb's" 
is  not  open  to  various  interpretations;  it  has  a  plain,  posi- 
tive meaning.  Therefore,  when  prescribing,  specify  SQUIBB'S. 


18          SQUIBB'S  MATERIA  MEDICA 

Squibb's  Ampuls  (Cont.) 
Ergot   (Sterile). 

An  aqueous  solution  containing  the  active  constituents  of  ergot, 
free    from   inert   extractive.      Physiologically    tested   and   stand- 
ardized;   1    mil    (Cc.  or    16  min.)    equals  2   Gm.  best  Spanish 
ergot.     Box   of     6x1    Cc.   ampuls, 
Box   of    12   x    1    Cc.    ampuls, 

IRON   ARSENITE. 

And  combinations.  Discontinued  in  deference  to  the  ruling  of 
the  Council  on  Pharmacy  and  Chemistry  of  A.  M.  A. 

IRON  CITRATE  GREEN.     Discontinued;   see  under  this  title. 

Iron  Cacodylate 

Is  an  arsenical  compound  of  iron  employed  as  an  alterative  and 
hematinic  in  chlorosis,  leukemia,  lymphadenitis,  etc.  The  hypo- 
dermic dose  is  0.03  to  0.1  Gm.  (J/2  t°  1J/2  grains)  daily. 
0.03  Gm.  (J/2  gr.)  in  I  Cc.  ampuls,  box  of  a  dozen, 

Mercury  Iodide  Red 

Is  a  mercurial  commonly  employed  hypodermically  in  syphilis. 
It  is  supplied  in  I  percent,  oily  solution,  in  1  Cc.  ampuls,  each 
thus  containing  0.01  Gm.  (!/£  gr.)  of  the  medicament.  Per  box 
of  1  dozen  ampuls, 

Mercury  Salicylate 

Is  offered  in  sterile  suspension  in  emulsion  of  wool-fat  and 
almond  oil.  It  is  a  favorite  with  many  physicians  in  the  sub- 
cutaneous treatment  of  syphilis.  0.065  Gm.  (1  gr.)  in  1  Cc. 
ampuls,  box  of  1  dozen, 

Quinine  Dihydrochloride 

Contains  about  75  percent,  of  quinine  alkaloid,  and  is  the  most 
readily  soluble  simple  salt  of  quinine.     Hence  it  is  well  adapted 
for  intramuscular  injection  as  an  anlipenodic  in  obstinate  cases 
'     of  malarial  fever.     Sizes: 

0.25  Gm.  (  33/4  grs.)  in  2  Cc.  ampuls,  box  of  I  dozen, 
0.5  Gm.  (7]/2  grs.)  in  2  Cc.  ampuls,  box  of  1  dozen, 
1  Gm.  (I5J/2  grs.)  in  2  Cc.  ampuls,  box  of  1  dozen, 

box  of  six, 

Quinine  and  Urea  Hydrochloride 

Also  known  as  Carbamidated  Quinine  Dihydrochloride,  contains 
about  70  percent,  of  alkaloidal  quinine  and  is  soluble  in  an  equal 
part  of  water.  Its  1  percent,  solution  is  employed  by  injection 
as  a  local  anesthetic,  slower  but  more  prolonged  in  action  than 
cocaine,  and  non-toxic;  in  10  to  20  percent,  solution  it  is  applied 
topically  to  mucous  membranes  and  wound  surfaces.  As  an 
antiperiodic  it  is  injected  deep  into  the  gluteal  or  deltoid  mus- 
cles. Offered  in  sterile  aqueous  solutions  as  follows: 

0.25  Gm.  (  33/4  grs.)  in  2  Cc.  ampuls,  box  of  1   dozen, 

0.5     Gm.  (   7'/2  grs.)  in  2  Cc.  ampuls,  box  of  1   dozen, 

1         Gm.  (15'/2  grs.)  in  2  Cc.  ampuls,  box  of  1   dozen, 

1%  solution,  for  local  anesthesia,  in  I  Cc.  ampuls,  box  of  1  doz., 

1  %,  solution,  for  local  anesthesia,  in  5  Cc.  ampuls,  box  of  six. 


SQUIBB'S  MATERIA  MEDICA          19 

Squibb's  Ampuls   (Cont.) 
Silver   Nitrate    1  %   Solution  box  of  1  dozen, 

For  preventing  ophthalmia  neonatorum,  1  or  2  drops  being 
instilled  into  each  eye. 

Sodium  Cacodylate 

Though  it  contains  35  percent,  of  metallic  arsenic  (equivalent 
to  47  percent,  of  arsenic  trioxide  [so-called  arsenous  acid]),  is 
regarded  as  a  relatively  non-toxic  succedaneum  for  the  ordinary 
arsenical  preparations  in  skin  diseases-,  chlorosis,  malarial 
cachexia,  etc.,  and  it  has  lately  come  to  the  fo.re  in  the  treatment 
of  syphilis,  by  intramuscular  injection.  For  the  latter  purpose 
the  ordinary  dose  is  0.45  Gm.  (7  grs.)  for  men,  0.4  Gm.  (6  grs.) 
for  women,  and  0.05  Gm.  (24  §r-)  f°r  infants. 

0.05  Gm.  (%  gr.)  in  1  Cc.  ampuls,  box  of  1  dozen, 
0.13  Gm.  (2  grs.)  in  1  Cc.  ampuls,  box  of  1  dozen, 
0.2  Gm.  (3  grs.)  in  1  Cc.  ampuls,  box  of  1  dozen, 
0.45  Gm.  (7  grs.)  in  1  Cc.  ampuls,  box  of  1  dozen, 

Amyl  Acetate,  Squibb  bottle,  Ib. 

CsHn.CiHsOo.      Colorless  liquid;    agreeable,   pear-like  odor. 
«        Slightly  soluble  in  water;   miscible.  with  alcohol,  ether.     Solvent 

of  resins;   constituent  of  fruit  essences  and  perfumes;    Reagent. 

©  Amyl  Nitrite,  Squibb  ampul,  oz.         ;  14  oz. 

covered  tubules,  3  minims,  box  of  10, 
covered  tubules,  5  minims,  box  of  10, 

Amylis  Nitris.  C-jHuNOo.  Clear,  yellowish  liquid;  ethereal, 
fruity  odor;  pungent  aromatic  taste.  Contains  when  fresh  80 
percent.  C-,HiiNC>2.  Is  free  from  water  and  aldehyde,  and 
contains  much  less  than  permissible  limit  of  free  acid.  On 
keeping,  it  loses  in  strength  and  becomes  more  acid.  Miscible 
with  alcohol,  ether;  almost  insoluble  in  water.  Offered  in 
tubules  covered  with  tubular  braid,  which  acts  as  absorbent  and 
inhaler.  For  use,  a  tubule  is  broken  between  the  thumbs  and 
fingers  and  .the  vapor  inhaled  from  the  -braid  covering.  Prompt 
Vaso-dilator;  chiefly  in  spasms  of  angina  pectoris,  asthma, 
general  convulsions,  fainting,  etc.  Average  Dose :  3  minims 
(0.2  mil  [Cc.]),  by  inhalation.  Antidotes:  atropine;  ergot  or 
strychnine  hypodermically.  Keep  in  a  cool  place,  and  disturb 
as  little  as  possible.  Inflammable! 

Amylopsin.        See  Diastase  from  Pancreas. 

ANGELICA  FRUIT. 

Angelica  Fructus,  N.  F.;  Angelica  Seed.  Ripe  fruit  of  An- 
gelica Archangelica  and  other  species  of  Angelica  (Fam.  Um- 
bellifera).  Aromatic  Stomachic,  Carminative.  Average  Dose : 
15  grains  (1  Gm.). 

The  prices  of  the  Squibb  Products  are  in  all  instances  as  low  as 
the  quality  and  quantity  of  ingredients  and  the  expense  of  man- 
ufacture allow.  They  include  containers,  packing  and  boxing.  When 
ordering  or  prescribing  medicinal  products,  specify  SQUIBB'S. 


20         SQUIBB'S  MATERIA  MEDICA 

ANGELICA  ROOT. 

Angelical  Radix,  N.  F.  Rhizome  and  roots  of  Angelica  atro- 
purpurea  (Fam.  Umbelli  ferae)  and  other  species.  Stimulating 
Expectorant.  Average  Dose:  30  grains  (2  Cm.). 

Anise,  Squibb  Whole  tin,  5  Ibs.,  per  Ib.         ;  Ib. 

Anisum;  Aniseed.  Dried  ripe  fruit  of  Pimpinella  Anisum 
(Fam.  Umbellifera),  obtained  from  cultivated  plants  only,  of 
fine  aromatic  odor  and  taste.  Aromatic  Carminative.  Average 
Dose:  8  grains  (0.5  Gm.). 

Anodyne,   Hoffmann's.         See  Spirit  Ether  Compound. 

Antidote,  Arsenic,  Squibb  per  set, 

Iron  Hydroxide  (Ferric)  with  Magnesium  Oxide.  In  two  bot- 
tles, one  containing  diluted  solution  of  tersulphate  of  iron,  the 
other  a  mixture  of  magnesia  and  water;  all  in  such  proportions 
that  when  combined  there  is  produced  official  Fe.ni  Hydroxidum 
cum  Magnesii  Oxido.  Valuable  for  emergency  use. 

Antifebrin.         See  Acetanilid.  , 

Antilithic,  Granular  Effervescent.      See  Sodium  Phosphate 
Compound,   Granular  Effervescent. 

ANTIMONY  OXIDE. 

Anlimonii  Oxidum,  N.  F.  SboOs.  White  or  grayish-white, 
odorless,  tasteless  powder.  Insoluble  in  ordinary  solvents.  Ex- 
pectorant, Emetic.  Average  Dose:  1  grain  (0.06  Gm.). 

ANTIMONY  SULPHURATED. 

Anlimonium  Sulphuralum,  N.  F. ;  Kermes  Mineral;  Red  An- 
timony Sulphide.  Chiefly  SboSs,  with  small  quantities  anti- 
mony trioxide,  sodium  pyroantimonate  and  sulphur.  Reddish- 
brown,  odorless,  tasteless  powder.  Insoluble  in  usual  solvents. 
Obsolescent  Cathartic,  Alterative,  Emetic.  Ordinary  Dose:  2 
grains  (0.13  Gm.) ;  emetic,  10  grams  (0.65  Gm.). 

0  Antimony  and  Potassium  Tartrate,  Squibb 

bottle,  Ib.         ;  %  Ib.          ;  oz. 

Anlimonii  ei  Polassii  Tartras ;  Tartar  Emetic;  Tartrated  Anti- 
mony. 2K(SbO)C4H4O<j.HoO.  White,  odorless,  granular 
powder;  sweet,  afterwards  disagreeable  metallic  taste.  1  Gm. 
dissolves  in  12  mils  (Cc.)  water,  15  glycerin.  Nauseant  Ex- 
pectorant, Emetic;  Pustulant  externally.  Average  Dose:  ex- 
pectorant, 1/i2  gr.  (0.005  Gm.) ;  emetic,  J/2  gr.  (0.03  Gm.). 
Best  to  begin  with  small  .doses  (Voo  gr.  [0.001  Gm.]),  which 
may  be  repeated  hourly.  Incompatible  with  antipyrine,  mer- 
curic chloride,  alkaline  carbonates,  tannic  acid,  and  vegetable 
infusions  containing  tannin.  (See  also  Wine;  Reagents  [Part 
IV].) 


SQUIBB'S  MATERIA  MEDICA         21 

'©  Antipyrine,  Squibb  bottle,  oz. 

Antipyrina;  Phenyldimethylpyrazolone ;  Phenazone;  Metho- 
zine.  CnHi2N2O.  White,  almost  odorless,  slightly  bitter, 
crystalline  powder.  1  Gm.  dissolves  in  about  1  mil  (Cc.) 
water,  1 .3  mils  alcohol,  0.7  mil  chloroform,  43  mils  ether. 
Antipyretic  and  Analgesic,  internally;  Styptic  and  Antisep- 
tic, externally.  Average  Dose:  5  grains  (0.3  Gm.).  Applied 
topically  in  1  :8  ointment,  or  pure,  or  in  20  percent,  solution  (in 
bleeding).  Incompatible  with  alum,  amyl  nitrite,  benzoates, 
ferric  chloride,  carbolic  acid,  calomel,  iodides,  resorcin,  sodium 
bicarbonate,  spirit  nitrous  ether  (when  not  very  recently  made), 
tartar  emetic  and  tannic  acid,  in  solution;  with  chloral  hydrate 
and  betanaphthol  on  trituration;  astringent  infusions.  Anti* 
dotes:  stimulants;  atropine  or  strychnine  subcutaneously ; 
oxygen. 

ANTIPYRINE  SALICYLATE.    See  Salipyrine. 
APIOL,  LIQUID.     See  Oleoresin   Parsley  Fruit. 

APOCYNUM. 

Apocynum,  N.  F. ;  Black 'Indian  or  Canadian  Hemp.  Dried 
rhizome  and  roots  of  Apocynum  cannabinum  (Fam.  Apocy- 
nacece).  Cardiac  Tonic,  of  digitalis  group.  Average  Dose:  12 
grains  (0.75  Gm.) 

f0  APOMORPHINE  HYDROCHLORIDE  (CRYSTALS). 

Apomorphina:  Hydrochloridum.  CiYHiTNOo.HCI-j-J/^^O. 
Alkaloidal  derivative  of  morphine.  Grayish-white,  odorless 
prisms,  turning  green  on  exposure  to  light  and  air.  1  Gm.  dis- 
solves in  50  mils  (Cc.)  water,  50  alcohol;  slightly  soluble 
in  chloroform,  ether.  Prompt,  centrally  acting  Emetic  for 
hypodermic  use;  nauseant  Expectorant;  Sedative  (in  delirium 
tremens).  Average  Dose:  expectorant  and  sedative,  1/20  gr- 
(0.003  Gm.);  emetic,  hypodermically  1/12  gr.  (0.005  Gm.), 
by  mouth  ]/(,  gr.  (0.01  Gm.).  Its  solutions  decompose  rapidly. 
(See  also  Tablets  [Part  II].) 

Apparatus  Stand  (Improved),  Squibb 

For  filtering,  holding  burettes,  supporting  condensers,  holding 
separatory  funnels,  and  supporting  crucibles  and  small  beakers. 
This  device  has  been  in  use  in  the  Squibb  Laboratories  for 
some  time  and  has  proved  very  satisfactory.  It  consists  of  a 
nickel-plated,  upright  rod,  about  22  inches  in  height  and  1/4 
inch  in  diameter,  secured  in  an  iron  cylinder  base.  Several 
attachments,  adapted  for  various  chemical  manipulations,  can 
be  readily  fitted  to  the  rod.  These  special  attachments 
consist  of  spring  clamps  which  slide  closely  over  the  rod 
and  lock  automatically  by  binding  on  the  same.  A  clamp  is 


If  difficulty  is  experienced  in  procuring  any  Squibb  product, 
in  the  original  packages  here  listed,  please  notify  us;  we 
shall  see  that  your  wants  are  met  promptly  and  satisfactorily. 


22          SQUIBB'S  MATERIA  MEDICA 

Apparatus  Stand  (Improved),  Squibb  (Cont.) 

easily  shifted  up  or  down  or  swung  sideways  by  9  slight  pres- 
sure. To  move  an  attachment,  take  hold  of  the  base  of  the 
stand  with  one  hand  and  slide  or  pull  the  spring  with  the  other, 
keeping  the  direction  of  the  pull  parallel  to  the  rod.  Do  not 
attempt  to  remove  an  attachment  while  supporting  an  object, 
since  its  weight  locks  it  to  the  rod;  the  greater  the  downward 
pressure  the  more  firmly  the  attachment  locks  itself.  It  is 
advisable  to  apply  a  little  petrolatum  over  the  rod  as  lubricant 
and  also  to  protect  the  parts  from  rusting.  Should  the  attach- 
ments fail  to  slide  easily,  remove  them  and  rub  the  rod  lightly 
with  emery  powder;  if  the  attachments  slide  too  freely,  the 
springs  should  be  removed  and  tightened  by  means  of  pliers. 
The  advantages  of  Squibb 's  Improved  Apparatus-Stand  over 
other  such  stands  are  in  its  stability,  neat  appearance  and  com- 
pactness. The  stand  is  simple,  portable  and  can  be  used  for 
many  simultaneous  operations.  Its  uses  are:  (I)  for  filtering; 
(2)  for  holding  burettes  absolutely  rigid,  and  perpendicular, 
permitting  them  to  be  easily  moved  up  or  down;  (3)  for  sup- 
porting light  condensers;  (4)  for  holding  separatory  funnels 
and  pipettes;  (5)  for  supporting"  crucibles  and  small  beakers. 
After  use,  the  apparatus  can  be  set  aside  and  occupies  no 
more  space  than  an  ordinary  reagent  bottle. 

APPLE  JUICE. 

Succus  Pomorum,  N.  F.  Freshly  expressed  juice  of  sound, 
ripe,  sour  apples,  the  fruit  of  cultivated  varieties  of  Pyrus 
Malus  (Fam.  Rosaces). 

Aqua   Ammoniac.          See  Ammonia  Water. 

Aqua  Fortis.        See  Acid  Nitric. 

Aqua  Regia.         See  Acid  Nitrohydrochloric. 

ARALIA. 

Aralia,  N.  F.;  American  Spikenard.  Dried  rhizome  and 
root  of  Aralia  racemosa  (Fam.  Araliacea).  Alterative,  Dia- 
phoretic. Average  Dose:  30  grains  (2  Cm.). 

ARBOR  VITVE.     See  Thuja. 
ARGENTUM    CREDE.      See    Collargol. 

ARGONIN. 

Silver-casein.  Nearly  white  powder;  4.28  percent,  silver.  Sol- 
uble readily  in  water.  Antigonorrheic,  Astringent. 

ARGYROL. 

Silver-vitellin.  Black,  hygroscopic  scales;  20  to  25  percent, 
silver.  Soluble  freely  in  water  or  glycerin;  insoluble  in  alcohol 
or  oils.  Anligonorrheic,  Astringent,  Antipyic.  Used  in  10  to 
25  percent,  solutions. 


SQUIBB'S  MATERIA  MEDICA          23. 

ARISTOCHIN. 

Aristoquin;  Diquinine  Carbonic  Ester.  White,  odorless,  taste- 
less powder;  96  percent,  quinine.  Soluble  in  chloroform;  in- 
soluble in  water;  difficultly  soluble  in  alcohol,  very  sparingly 
in  ether.  Succedaneum  for  quinine  sulphate.  Dose:  2  io  15 
grains  (0.13  to  1  Gm.).  Incompatible  with  acids  or  alkalies. 

ARISTOL.     Brand  of  Thymol   Iodide. 

Arnica  Flowers,  Squibb 

Ground   for  Percolation  tin,  lb. 

Arnica.  Dried  flower-heads  of  Arnica  monlana  (Fam.  Com- 
posiid),  especially  free  from  sophistication  with  flowers  of  other 
plants.-  Produce  galenicals  of  correct  quality,  odor  and  taste. 
Feeble  Rubefacient,  used  chiefly  as  tincture.  (See  Fluid- 
extract;  Tincture.) 

Arsenic  Antidote.       See  Antidote,   Arsenic. 

Arsenic  Iodide,  Squibb  g.  s.  bottle,  oz. 

Arseni  lodidum.  Aslg;  Arsenic  Triiodide.  Orange-red,  odor- 
less crystals  or  powder.  82.7  percent,  iodine  and  16.3  percent, 
arsenic.  1  Gm.  dissolves  in  about  12  mils  (Cc.)  water,  with 
partial  decomposition;  soluble  in  alcohol,  chloroform,  ether. 
Alterative,  in  cancer  (internally  and  externally),  scrofula, 
leprosy,  etc.  Average  Dose:  1/n>  gr.  (0.005  Gm.),  in  pills  or 
tablets.  Keep  from  light.  (See  also  Tablets  [Part  II].) 

0  Arsenic  Trioxide,  Squibb 

(Acid  Arsenous  Powdered)  bottle,  14  lb.         ;  oz 

Arseni  TrioxiJum;  Arsenous  Acid;  As^GV  Soluble  in  water, 
freely  in  glycerin,  sparingly  in  alcohol  or  ether.  Aqueous 
solubility  is  increased  by  tartaric  or  hydrochloric  acid.  Anti- 
periodic,  Alterative,  Caustic.  Average  Dose :  !/3Q  grain  (0.002 
Gm.).  Antidotes:  arsenic  antidote,  emetics;  milk  or  eggs; 
magnesia  in  milk.  Incompatible  with  tannic  acid  and  infusion 
cinchona  and  other  vegetable  astringent  infusions,  tinctures  and 
decoctions;  also  with  salts  of  iron  and  magnesium,  lime- 
water,  etc.  (See  also  Reagents,  Part  IV;  Tablets  [Part  II].) 

ARSENPHENOLAMINE-S.     See     Neoarsphenamine. 

ARSEKOBENZOL.     Brand    of   Arsphenamine    (Salvarsan). 

®  ARSPHENAMINE. 

Name  adopted  by  Federal  Trade  Commission  for  Diamino- 
dihydroxy-arsenobenzene  Hydrochloride  (first  introduced  as 
Salvarsar  and  also  known  as  Arsenobenzol  and  Ehrlich's  606) 
as  made  in  America.  Yellow  powder,  containing  about  31.5 
percent  arsenic.  Readily  soluble  in  water.  Alterative  and 
Antiluetic;  succedaneum  for  arsenic,  but  used  mainly  in 
syphilis  by  intravenous,  intramuscular  or  hypodermic  injection. 
Dose  (in  lues) :  men,  9  grains  (0.6  Gm.) ;  women,  6  grains 
(0.4  Gm.);  children,  2  to  5  grains  (0.13  to  0.3  Gm.). 


The  Squibb  products  are  recognized  everywhere  as  the  Quality 
Standard.  They  are  of  uniform  purity  and  strength,  hence 
therapeuticallv  dependable.  When  ordering  cr  prescribing  med- 
icinal products,  you  will  do  well  always  to  specify  SQUIBB'S. 


24         SQUIBB'S  MATERIA  MEDICA 

0  ASAFETIDA. 

Asafoetida.  Gum-resin  obtained  by  incising  rhizome  and  roots 
of  Ferula  Asaf&tida,  F.  fcetida,  and  other  species  of  Ferula 
(Fam.  Umbellifera).  Soft  mass;  persistent,  garlicky  odor; 
bitter,  acrid  taste.  Carminative,  Sedative;  in  hysteria,  asthma, 
etc.  Average  Dose:  4  grains  (0.25  Grn.).  (See  also  Tablets 
[Part  II].) 

ASARUM. 

Asarum,  N.  F.;  Canada  Snake-root.  Dried  rhizome  and  roots 
of  Asarum  canaJense  (Fam.  Arislolochiacete) .  Carminative, 
Flavor;  similar  to  ginger.  Average  Dose:  30  grains  (2  Gm.). 

Asbestos  Wool  Reagent.       See  Reagents  (Part  IV). 

ASCLEPIAS. 

Asclepias,  N.  F.;  Pleurisy  Root.  Dried  roots  of  Asclepias 
luberosa  (Fam.  Asclepiadacece).  Slight  odor;  bitterish,  dis- 
agreeable, acrid  taste.  Domestic  remedy  for  pleurisy;  also 
used  as  Diaphoretic.  Average  Dose:  30  grains  (2  Gm.). 
(See  also  Fluidextract.) 

ASPIDIUM. 

Aspidlum;  Male  Fern.  Rhizome  and  stipes  of  Dryopteris 
Filix-mas  or  D.  marginalis  (Fam.  Polypodiaceas).  Anthelmin- 
tic.  Average  Dose:  1  drachm  (4  Gm.). 

ASPIDOSPERMA. 

Aspic!  osperma;  Quebracho.  Dried  bark  of  Aspidosperma 
Quebracho  bianco  (Fam.  Apocynacea).  Respiratory  Tonic. 
Antidyspneic ;  ckiefly  in  asthma  and  emphysema.  Average 
Dose:  1  drachm  (4  Gm.).  (See  also  Fluidextract.) 

ASPIRIN.     Brand  name   for  Acetylsalicylic  Acid. 
ATOPHAN.      See    Acid    Phenylcinchoninic. 

0  ATOXYL. 

Sodium  Arsanilate.  White,  odorless  powder;  about  22  per- 
cent, arsenic.  Soluble  in  water.  Alterative,  Antiluetic.  Dose: 
J/3  to  3  grains  (0.02  to  0.2  Gm.),  hypodermically  every  second 
day. 

©  Atropine,  Squibb  J/g-oz.  vial,          ;  10-gr.  vial, 

5-gr.  vial, 

Alropina.  Cj^HosOsN.  An  alkaloid  from  Alropa  Bella- 
donna and  other  plants  of  Solanacecs.  White,  odorless,  bitter, 
acrid  crystals.  1  Gm.  dissolves  in  455  mils  (Cc.)  water,  2 
alcohol  27  glycerin,  1  chloroform,  25  ether.  Respiratory  and 
Cardiac  Stimulant;  Antispasmodic,  Antihydrotic,  Antisialagogue. 
Average  Dose:  1/120  gr-  (0.0005  Gm.).  Acts  within  J/2  hour, 
eliminated  within  3  hours.  Applied  locally  as  oleate.  Anti- 
dotes: tannin,  then  emetics;  morphine,  pilocarpme,  physostig- 
mme,  aconitme. 


SQUIBB'S  MATERIA  MEDICA          25 

0  Atropine  Sulphate,  Squibb 

j/g-oz.  vial,  ;  10-gr.  vial,  ;  5-gr.  vial, 
Atropinai  Sulphas.  (CiiHosOsN^.H^O.!.  White,  crys- 
talline, odorless,  bitter  powder.  I  Gm.  dissolves  in  0.4  mil 
(Cc.)  water,  5  mils  alcohol,  2.5  glycerin,  420  chloroform, 
3200  ether.  Uses  same  as  alkaloid,  but  largely  as  Mydriatic, 
in  1/2  percent,  solution.  Average  Dose:  I/IOQ  grain  (0.0005 
Gm.). 

BACILLUS  BULGARICUS  CULTURE. 

Offered  in  liquid  and  tablet  forms.  Antizymotic  internally, 
Antipyic  topically.  Dose :  liquid,  7  mils  (Cc.) ;  tablets,  1  or 
2,  after  meals. 

Baking  Powder,  Squibb  tin,  Ib.         ;  %  Ib. 

After  a  formula  approved  by  the  U.  S.  Government,  but  with 
slight  modification  to  enhance  its  effectiveness.  Free  from  all 
injurious  substances,  hence  perfectly  harmless  to  health.  Owing 
to  the  fact  that  this  powder  is  made  from  the  purest  materials 
and  thoroughly  dried  before  putting  up,  it  should  be  used  with 
moderation;  it  is  more  active  than  most  powders — a  level 'tea- 
spoonful  of  Squibb's  Baking  Powder  is  equivalent  to  a  heaping 
teaspoonful  of  the  regular  baking  powders  of  the  market.  Keep 
the  can  well  closed  and  in  a  dry  place. 

BALM    GILEAD   BUDS.     See   Balsam   Poplar   Buds. 

BALSAM  POPLAR  BUDS. 

Pofiull  GemmcE,  N.  F.;  Balm  of  Gilead  Buds.  Air-dried, 
closed  winter  leaf-buds  of  Populus  nigra  or  P.  bahamifera 
(Fam.  Salicacece).  Anticatarrhal,  Expectorant;  similar  to 
cubeb  or  turpentine. 

BALSAM  COPAIBA.     See  Copaiba. 

Balsam,  Friars'  or  Turlington's.     See      Tincture      Benzoin 
Compound. 

©  Balsam   Peru,   Squibb  bottle,  Ib.         ;  ]/4  Ib. 

Bahamum  Peruvianum.  From  Toluifera  Pereirce  (Fam.  Le§u- 
minoscE).  Soluble  in  alcohol  and  chloroform  with  not  more  than 
slight  opalescence;  partly  in  ether.  Contains  50  to  56  percent, 
cinnamem.  Thick,  dark-brown  liquid;  vanilla-like  odor;  bitter, 
acrid  taste.  Sp.  gr.  1.130  to  1.160.  Antiseptic,  Alterative, 
Expectorant.  Used  chiefly  externally,  on  wounds,  ulcers, 
chilblains,  etc.;  internally,  in  chronic  catarrh,  asthma,  phthisis, 
etc.  Dose:  10  to  20  grains  (0.65  to  1.3  Gm.).  Incompatible 
with  iodoform  in  substance,  and  hydrogen  dioxide. 

Since  we  make  only  one  quality  of  each  product,  that  best 
suited  to  the  purposes  intended,  the  specification  "Squibb's" 
is  not  open  to  various  interpretations,  but  has  a  plain,  positive 
meaning.  When  ordering  or  prescribing,  specify  SQUIBB'S. 


26          SQUIBB'S  MATERIA  MEDICA 

0  Balsam  Tolu,  Squibb  tin,  Ib. 

Balsamum  Tolulanum.  From  Toluifera  Balsamum  (Fam.  Legu- 
minoste).  Free  from  rosin  and  copaiba  and  in  other  respects 
fully  U.  S.  P.  Yellow-brown,  plastic  solid,  becoming  brittle 
when  old  or  dried  or  exposed  to  cold;  vanilla-like  odor;  mild 
aromatic  taste.  Soluble  in  alcohol,  chloroform,  ether.  Expec- 
torant; used  chiefly  as  its  syrup,  a  pleasant  vehicle.  Dose:  8  to  15 
grains  (0.5  to  1  Gm.).  (See  also  Fluid;  Syrup;  Tincture.) 

BAPTISIA. 

Baptisia,  N.  F.;  Wild  Indigo.  Dried  roots  of  Baplisia  iinc- 
toria  (Fam.  Leguminos«).  Used  as  Astringent.  Average 
Dose:  15  grains  (1  Gm.).  1 

BARBITAL-SODIUM  (SODIUM  DIETHYLBARBITURATE) 

This  is  the  name  adopted  by  the  Federal  Trade  Commission 
for  the  product  known  by  various  brand  names,  such  as:  Medi- 
nal,  Veronal-Sodium,  etc.  White  powder,  of  bitter-alkaline 
taste.  Soluble  in  5  parts  water.  Hypnotic;  used  also  hypo- 
dermically  and  by  rectum.  Dose:  5  to  1  5  grains  (03  to  1  Gm.). 

BARBERRY.     See    Berberis. 

0  BARBITAL. 

Name  adopted  by  Federal  Trade  Commission  for  Diethylma- 
lonylurea  or  Diethylbarbituric  Acid  (first  introduced  under  the 
trade  name  Veronal  and  also  known  as  Malo-Urea)  as  made 
in  America  during  the  suspension  of  the  German  patents. 
White,  crystalline,  odorless,  slightly  bilter  powder.  Soluble  in 
about  150  parts  water,  readily  in  ether,  slightly  in  chloroform. 
Hypnotic.  Dose:  5  to  15  grains  (0.3  to  1  Gm.),  with  a  hot  drink. 

Barium  Acetate  Reagent.        See  Reagents   (Part  IV). 

Barium  Carbonate  Reagent.        See  Reagents  (Part  IV). 

Barium   Chloride   Reagent.     See   Reagents    (Part   IV). 

Barium    Hydroxide    Reagent.     See    Reagents     (Part    IV). 

Barium  Nitrate  Reagent.         See  Reagents  (Part  IV). 

Barium  Sulphate  for  X=Ray  Work,  Squibb 

carton,  Ib.  ;  J/4  Ib. 

BaSO).  White,  odorless,  tasteless,  quite  bulky  powder.  In- 
soluble in  usual  organic  solvents.  Barium  Sulphate  has  come 
into  use  for  X-Ray  work  on  the  stomach  and  intestines.  In- 
sJances  of  poisoning  that  have  occurred  point  out  the  necessity 
of  employing  only  a  perfectly  pure  grade  free  from  soluble 
barium  salts,  which  latter  are  the  cause  of  toxic  symptoms.  The 
article  here  offered  is  perfectly  free  from  these  noxious  soluble 
salts,  and  is  especially  prepared  for  X-Ray  work.  Being  in- 
soluble in  water,  acids  or  alkalies,  it  passes  through  the  system 
unchanged  and  unabsorbed.  Hence  no  untoward  action  what- 
ever need  be  feared.  Also  suitable  for  use  as  Reagent.  When 
ordering  Barium  Sulphate  for  X-Ray  work  specify  "Squibb." 
Send  for  literature. 

BARKER'S  POST-PARTUM  PILLS.    See  Pills  Laxative,  Post-Partum. 
Bateman's  Pectoral   Drops.       See  Tincture,  Pectoral. 


SQUIBB'S  MATERIA  MEDICA          27 

BAYBERRY  BARK. 

Myrica,  N.  F.;  Candleberry;  Wax  Berry.  Dried  bark  of 
root  of  Myrica  cerifera  (Fam.  Myricace<e).  Used  as  Diges- 
tive, Carminative,  Nerve  Stimulant.  Average  Dose:  8  grains 
(0.5  Gm.). 

BAY   RUM.     See   Spirit   Myrcia   Compound. 
BEARBERRY  LEAVES.    See  Uva  Ursi. 

0  Belladonna  Leaves,  Squibb 

Ground  for  Percolation  tin,  lb. 

BellaJonnce  Folia;  Deadly  Nightshade  Leaves.  Dried  leaves 
and  tops  of  Alropa  Belladonna  (Fam.  Solanacecs).  Assays  not 
less  than  0.3  percent,  alkaloids.  Preparations  made  from  this 
leaf  may  assay  above  official  standard  and  must  be  adjusted 
accordingly.  Anodyne,  Antispasmodic,  Antihydrotic.  Aver- 
age Dose:  1  grain  (0.065  Gm.).  (See  also  Extract;  Fluid- 
extract;  Ointment;  Tincture.) 

BELLADONNA  ROOT. 

Belladonna  Radix.  Assays  not  less  than  0.45  percent,  alka- 
loids. Average  Dose:  %  grain  (0.05  Gm.).  (See  also  Ex- 
tract; (Fluid  extract) 

Benzaldehyde,    Squibb  bottle,  lb.         ;  %  lb. 

Benzaldehydum ;  Benzoic  Aldehyde;  Artificial  Essential  Oil 
Almond.  Contains  not  less  than  85  percent.  C7H(;O.  Color- 
less or  yellowish  liquid;  odor  of  bitter  almond;  burning  taste. 
Sp.  gr.  about  1.045.  Miscible  with  alcohol,  ether,  oils;  slightly 
soluble  in  water.  Non-poisonous  substitute  for  oil  bitter  almond; 
also  Flavoring.  Average  Dose:  1/2  minim  (0.03  mil). 

BENZENE. 

Benzol  Medicinal.  Cf;H(j.  From  light  oil  of  coal  tar.  Color- 
less liquid;  strong  odor;  burning  taste.  Soluble  in  alcohol, 
ether;  insoluble  in  water.  Used  in  Hodgkin's  disease,  leu- 
kemia, etc.  Dose:  8  to  15  minims  (0.5  to  1  mil  [Cc.])  four 
times  a  day,  in  capsules  or  as  emulsion.  Use  cautiously. 

BENZIN,  PETROLEUM,  PURIFIED. 

Benzinum  Purificalum ;  Petroleum  Ether.  Purified  distillate 
from  petroleum,  consisting  of  hydrocarbons  chiefly  of  marsh- 
gas  series.  Sp.  gr.  0.638  to  0.660.  Freely  soluble  in  alcohol; 
miscible  with  chloroform,,  benzene,  and  oils  (excepting  castor 
oil)  ;  insoluble  in  water.-  Antiparasitic  dermic;  in  scabies, 
pediculosis,  barber's  itch,  etc.;  but  used  chiefly  pharmaceutically. 
Very  inflammable. 


The  founder  of  the  House  of  Squibb,  Dr.  Edward  R.  Squibb, 
not  only  had  high  ideals,  but  lived  and  labored  for  them;  and, 
in  the  words  of  William  Miller  Bartlett,  "the  House  of  Squibb 
stands  today  as  a  living  monument  to  the  honor,  integrity,  zeal 
and  devotion  of  its  founder." 


28         SQUIBB'S  MATERIA  MEDICA 

0  Benzoin,    Squibb  tin,  lb.        ;  ]/4  lt>- 

Benzoinum;  Gum  Benjamin;  Gum  Benzoin.  Extra  select  Siam 
gum,  in  nice,  clean  tears;  wholly  different  from  the  regular 
market  article.  Balsamic  resin  obtained  from  Styrax  Benzoin 
and  other  species  of  Styrax  (Fam.  Styracacea-).  Yields  less  than 
21/2  percent,  ash,  and  especially  rich  in  benzoic  acid.  Yellow- 
ish-brown, pebble-like  tears;  vanilla/-like  odor;  slightly  acrid 
taste.  Soluble  in  solution  sodium  or  potassium  hydroxide,  in 
5  parts  warm  alcohol.  Wound  Antiseptic,  1 :5  ointment;  Ex- 
pectorant, in  inhalations.  Used  mainly  technically  and  phar- 
maceutical ly.  Average  Dose:  15  grains  (1  Gnu).  (See  also 
Fluid;  Tincture). 

Benzoinated  Cream,  Squibb 

small  jars  per  doz.          ;  oz.  jars,  per  doz. 
l/2-oz.  tubes,  per  doz. 

This  medicated  Cold  Cream  has  been  supplied  for  many  years 
as  a  special  laboratory  product.  It  has  been  proved  a  most 
valuable  article  in  cases  where  the  action  of  ordinary  cold  cream 
is  insufficient  to  effect  prompt  relief.  It  differs  from  the  ordinary 
article  in  being  a  therapeutic  salve  instead  of  a  simple  mechani- 
cal ointment.  It  is  used  for  the  same  purposes  for  which  cold 
cream  is  so  generally  employed,  but  being  compounded  with 
other  remedial  agents,  it  possesses  valuable  medicinal  properties 
which  permit  of  its  wider  and  more  beneficial  use  as  a  safe 
and  healing  application.  It  contains  benzoin,  camphor,  expressed 
oil  almond  and  natural  beeswax.  Emollient,  Antiseptic  and 
Antipruritic. 

Benzol  (Benzene)  Reagent.        See  Reagents  (Part  IV). 

Benzonaphthol.         See  Betanaphthol  Benzoate. 

BENZOSALIN. 

Methyl  Benzoylsalicylate.  Fine,  white  crystals,  of  faint  aro- 
matic odor.  Soluble  readily  in  chloroform,  moderately  in 
alcohol;  insoluble  in  water.  Intestinal  Antiseptic.  Dose:  8  to 
15  grains  (0.5  to  1  Gm.). 

BENZOSOL. 

Benzoyl-guaiacol;  Guaiacol  Benzoate.  CoH^OCHsyCeHs- 
CO;>.  White  powder;  slight  odor  and  taste;  54  percent,  guaia- 
col.  Soluble  in  alcohol,  chloroform;  sparingly  soluble  in  ether; 
insoluble  in  water.  Intestinal  and  Urinary  Antiseptic,  Anti- 
diabetic.  Dose:  3  to  10  grains  (0.2  to  0.65  Gm.). 

®  BENZOSULPHINIDE. 

Benzosulphinidum ;  Saccharin;  Benzoylsulphonic  Imide;  Glu- 
side.  CjHsOsNS.  White,  nearly  odorless  powder;  intensely 
sweet  taste.  1  Gm.  dissolves  in  290  mils  (Cc.)  water,  31 
alcohol;  slightly  soluble  in  ether  or  chloroform;  easily  in  am- 
monia water,  alkaline  hydroxide  or  sodium  bicarbonate  solution. 
About  500  times  as  sweet  as  cane  sugar.  Non-fermentable 
sweetener;  corrigent  of  bitter  or  acrid  drugs.  Rarely  medicinally, 
as  acidifier  of  urine  in  cystitis.  Average  Dose :  3  grains  (0.2 
Gm),  well  diluted.  (See  also  Tablets  [Part  II].) 


SQUIBB'S  MATERIA  MEDICA          29 

®  BenzosuIphinide=Sodium.      See  Sodium  Benzosulphinide. 

BERBERIS. 

Berberis,  N.  F. ;  Barberry  Root;  Oregon  Grape  Root.  Dried 
hrizome  and  roots  of  Berberis  aquifolium  and  other  species  of 
Berberis  (Fam.  Berberidacets) .  Bitter  Tonic,  like  hydrastis. 
Average  Dose:  30  grains  (2  Gm.).  (See  also  Fluidextract.) 

BESTUSCHEFF'S  TINCTURE.    See  Tincture  Iron  Chloride,  Ethereal. 

f  BETAEUCAINE  HYDROCHLORIDE. 

BetaeucaintB  HydrochloriJum ;  Trimethylbenzoyloxypiperidine 
Hydrochloride.  Ci5H2iNOo.HCl.  White,  odorless  powder. 
1  Gm.  dissolves  in  30  mils  (Cc.)  water,  35  alcohol,  6  chloro- 
form. Incompatible  with  alkalies  and  their  carbonates.  Local 
Anesthetic;  in  2  percent,  solution  for  eye,  5  to  10  percent, 
solution  for  nose  and  throat. 

©  Betanaphthol,  Squibb  1-oz.  vial 

Betanaphthol ;  Naphthol.  CioHiOH.  A  monohydroxy- 
phenol  occurring  in  coal  tar,  but  usually  made  from  naphtha- 
lene. Colorless  or  buff-colored,  shining  laminae;  faint,  phenol- 
like  odor;  sharp  taste.  1  Gm.  dissolves  in  about  1000  mils 
(Cc.)  water,  0.8  alcohol,  17  chloroform,  1.3  ether;  soluble  in 
glycerin,  olive  oil,  alkali-hydroxide  solutions.  Antiparasitic 
Dermic;  Intestinal  Antiseptic,  Anthelminthic.  Internally,  in 
typhoid  fever,  chronic  diarrhea,  etc.;  externally  in  psoriasis, 
scabies  and  other  parasitic  skin  diseases.  Also  used  as  Reagent. 
Average  Bose:  4  grains  (0.25  Gm.).  Applied  in  3  to  10 
percent,  ointment.  Incompatible  on  trituration  with  antipyrine, 
camphor,  menthol  or  phenol. 

Betanaphthol  Benzoate,  Squibb  1-oz.  vial 

Benzonaphthol.  CeHsCOo.CioHj.  Creamy-white,  nearly 
odorless  and  tasteless  needles  or  powder;  darkens  with  age. 
Soluble  in  alcohol,  ether,  chloroform.  Intestinal  Antiseptic. 

Dose:  3  to  8  grains  (0.2  to  0.5  Gm.). 
BETANAPHTHOL-EISMUTH.     See  Bismuth  Betanaphtholate. 
BETH    ROOT.     See    Trillium. 

BISMUTH   BETANAPHTHOLATE. 

Bismuthi  Belanaphiholas;  Betanaphthol-Bismuth.  Newly  offi- 
cial. 15  percent,  betanaphthol,  75  percent,  bismuth  oxide. 
Buff-colored  to  grayish-brown,  almost  odorless,  tasteless  powder, 
nearly  insoluble  in  water,  alcohol,  chloroform,  ether.  Intestinal 
Antiseptic.  Average  Dose:  8  grains  (0.5  Gm.). 


The  Squibb  Ideals  have  taken  concrete  form  in  the  Squibb 
Products;  these  are  universally  recognized  as  standards  of 
uniform  Purity  and  Efficacy,  that  is,  general  Excellence  and 
Reliability.  Specify  SQUIBB'S  when  prescribing  or  ordering. 


30          SQUIBB'S  MATERIA  MEDICA 

Bismuth  Carbonate.        See   Bismuth  Subcarbonate. 

Bismuth  Citrate,  Squibb  bottle,  oz. 

BiC6HoO7.  Dropped  from  U.  S.  P.  White,  odorless,  taste- 
less powder.  When  fresh  or  not  too  old,  soluble  in  ammonia 
water  and  solutions  alkaline  citrates;  insoluble  in  water  and 
alcohol.  Stomachic,  Astringent;  also  Reagent.  Ordinary  Dose: 
2  grains  (0.13  Gm.). 

Bismuth  Citrate  Soluble.     See  Bismuth  and  Ammonium  Citrate. 

Bismuth  (iallate  Basic.          See  Bismuth  Subgallate. 

Bismuth  Magma,  Squibb  bottle,  pint 

Magma  Bismulhi ;  Milk  of  Bismuth.  Yields  5.6  to  6.2  percent, 
bismuth  oxide.  Each  fluidounce  represents  equivalent  of  about 
40  grains  bismuth  subnitrate,  suspended  in  plain  distilled  water. 
Antacid,  Gaslro-intestinal  Astringent  and  Sedative.  Average 
Dose:  1  fluidrachm  (4  mils  [Cc.]).  Keep  protected  against 
light;  shake  well  before  dispensing. 

Bismuth,    Milk    of.     See    Bismuth    Magma. 

Bismuth    Nitrate    Reagent.     See    Reagents    (Part    IV). 

Bismuth  Oxide  Hydrated,  Squibb  bottle,  oz. 

Bi(OH)s.  White,  bulky,  odorless  powder.  To  make  Cremor 
Bismulhi  or  Cream  of  Bismuth,  mix  20  parts  of  this  oxide  with 
80  parts  water.  Antacid,  Gastric  Protective,  internally;  As- 
tringent, locally.  Also  Reagent.  Dose :  5  to  20  grains  (0.3 
to  1.3  Gm.). 

Bismuth  Oxychloride,  Squibb  bottle,  oz. 

Bismuthyl  Chloride;  Pearl  White.  Bi  O  Cl.  White,  odorless, 
lustrous  powder.  Soluble  in  acids;  insoluble  in  water.  Used 
in  face  powders,  etc. 

Bismuth  Oxyiodide,  Squibb  bottle,  oz. 

Bismuth  Subiodide.  BiOI.  Brownish-red,  odorless,  tasteless 
powder,  insoluble  in  ordinary  solvents.  Antiseptic,  Vulnerary. 
Dose:  3  to  10  grains  (0.2  lo  0.65  Gm.). 

Bismuth  Oxynitrate.          See  Bismuth  Subnitrate. 
Bismuth  Salicylate  Basic.          See   Bismuth  Subsalicylate. 

©  Bismuth  Subcarbonate,  Squibb 

bottle,  Ib.  ;  '/4  'b.  ;  oz. 

Bismuthi  S  ub  carbon  as ;  Bismuth  Carbonate  (BiO^COs- 
Yields  not  less  than  90  percent,  bismuth  oxide,  and  free  from 
alkalies,  arsenic,  alkaline  earths  and  heavy  metals.  White, 
odorless,  tasteless  powder.  Insoluble  in  water,  alcohol,  ether, 
etc.  Protective  Vulnerary,  Gaslric  Sedative,  Intestinal  Astrin- 
gent; also  used  as  Reagent  and  in  X-ray  work.  Average 
Dose:  8  grains  (0.5  Gm.).  Incompatible  with  sulphides,  sul- 
phur, acids  and  acid  salts.  (See  also  Tablets  [Part  II].) 


SQUIBB'S  MATERIA  MEDICA          31 

0  Bismuth  Subgallate,  Squibb 

bottle,  Ib.         ;  |4  Ib.          ;  oz. 

Bismuth!  Subgallas;  Basic  Bismuth  Gallate.  Bi(OH)2C7H5C>5. 
Yields  52  to  57  percent,  bismuth  oxide.  Contains  no 
free  gallic  acid.  Bright-yellow,  odorless  powder.  Soluble  in 
solutions  of  alkali  hydroxides;  insoluble  in  ordinary  solvents. 
Drying  Antiseptic  externally;  Astringent  internally.  Average 
Dose:  8  grains  (0.5  Cm.).  Applied  pure  or  as  10  to  20 
percent,  dusting-powder  or  ointment.  Incompatible  with  acids, 
alkalies,  sulphides  and  sulphur.  (See  also  Tablets  [Part  II].) 

Bismuth  Subiodide.       See  Bismuth  Oxyiodide. 

0  Bismuth  Subnitrate,   Squibb 

bottle,  Ib.         ;  J4  Ib.         ;  oz. 

Bismulhi  Subnilras ;  Magistery  of  Bismuth;  Bismuth  Oxy- 
nitrate.  BiONO3.H2O  or  Bi(OH)2NO3.  Pure,  nice  while 
and  bulky.  Not  only  fully  meets  the  U.  S.  P.  purity  require- 
ments, but  exceeds  them.  White,  odorless,  almost  tasteless  pow- 
der. Insoluble  in  ordinary  solvents.  Incompatible  "with  gallic, 
salicylic  and  tannic  acids,  solutions  of  alkaline  carbonates,  sul- 
phides and  sulphur.  Topical  and  Gastro-intestinal  Astringent 
and  Protective.  Average  Dose:  8  grains  (0.5  Cm.).  (See  also 
Reagents  [Part  IV];  Tablets  [Part  II].) 

0  Bismuth  Subsalicylate,  Squibb 

bottle,  Ib.          ;  %  Ib.          ;  oz. 

Bismuthi  Subsalicylas ;  Basic  Bismuth  Salicylate.  Bi(OH)o- 
CjHoOs.  Yields  62  to  66  percent,  bismuth  oxide.  White, 
or  nearly  white,  odorless,  tasteless  powder.  Insoluble  in  ord- 
inary solvents.  External  and  internal  Astringent  and  Anti- 
septic. Average  Dose:  8  grains  (0.5  Gm.).  Topically  used 
like  iodoform.  Incompatible  with  alcohol,  alkali  carbonates, 
and  bicarbonates,  tannin  and  iron  salts.  NOTE:  The  acid 
salicylate  is  nof  official,  and  should  not  be  dispensed  when 
"salicylate"  is  called  for  in  prescriptions.  (See  also  Tablets 
[Part  II].) 

Bismuth  and  Ammonium  Citrate,  Squibb 

bottle,  Ib.          ;  !4  Ib-          ;  oz. 

Bismuthi  et  Ammonii  Cilras;  Soluble  Bismuth  Citrate.  A  par- 
ticularly handsome  and  pure  product,  scaled  with  great  care. 
Yields  46  to  52  percent,  bismuth  oxide.  Shining,  pearly,  odor- 
less scales;  metallic  taste;  very  soluble  in  water,  sparingly  solu- 
ble in  alcohol.  Stomachic,  Astringent.  Average  Dose:  2  grains 
(0.13  Gm.).  Injected  in  urethritis  in  1:500  solution.  Keep 
well  stoppered;  becomes  opaque,  loses  ammonia,  and  sacrifices 
its  solubility  on  exposure. 

The  Squibb  Label  on  a  package  is  a  positive  guaranty  for  the 
uniform  Purity  and  Reliability  of  the  product.  We  make  only 
ONE  quality:  the  SQUIBB  quality;  and  our  prices  are  as  low 
as  they  can  be  made  for  that  quality.  Specify  SQUIBB'S. 


32          SQUIBB'S  MATERIA  MEDICA 

BITTER  APPLE.    See  Colocynth. 

BITTERSWEET. 

Dulcamara,  N.  F.  Dried  stems  and  branches  of  Solanum  Dul- 
camara (Fam.  Solanacece).  Used  as  Alterative.  Average 
Dose:  60  grains  (4  Gm.). 

BLACKBERRY  BARK.    See  Rubus. 

BLACK   COHOSH.     See   Cimicifuga. 

BLACK   DROP.     See   Vinegar   Opium. 

BLACK   HAW.     See   Viburnum    Prunifolium. 

BLACK   WASH.     See   Lotion,   Black. 

BLADDERWRACK.     See    Fucus. 

BLANCARD'S  PILLS.     See  Pills  Iron  Iodide. 

Blood,  Occult,  Test  Tablets.      See  under  Tablets   (Part  II). 

Blood=Root.  See  Sanguinaria. 

BLUE   COHOSH.      See   Caulophyllum. 

BLUE  FLAG. 

7ns  yersicolor,  N.  F.  Dried  rhizome  of  Iris  \>ersicolor  (Fam. 
Iridaceci).  Cathartic.  Average  Dose:  30  grains  (2  Gm.). 

BLUE   GUM   TREE.     See  Eucalyptus. 

Blue  Mass  or  Blue  Pill.         See  Mass  Mercury. 

Blue  Stone  or  Blue  Vitriol.  See  Copper  Sulphate. 

BLUE  VERVAIN.     See  Vervain. 

BOLDO. 

Boldo,  N.  F.  Leaves  of  BolJu  Boldus  (Fam.  Motiimiaceci). 
Aromatic,  Mild  Diuretic.  Average  Dose:  8  grains  (0.5  Gm.). 

BONESET.     See    Eupatorium. 

Borax.          See  Sodium  Borate. 

BORNYL  BROMOVALERATE.    See  Brovalol. 

Boroglycerin     Glycerite.     See    Glycerite     Beroglycerin. 

BRAYERA. 

Brayera,  N.  F.;  Kousso;  Cusso.  Dried  panicles  of  flowers  of 
Haneiiia  abyssinica  (Fam.  Rosaces).  Teniacide.  Average  Dose: 
240  grains  (16  Gm.). 


SQUIBB'S  MATERIA  MEDICA          33 

BROMETONE. 

Tribrominated  Tertiary  Butyl  Alcohol.  C4H7OBr3.  White 
crystals;  camphor-like  odor  and  taste.  Soluble  freely  in  al- 
cohol, ether,  chloroform;  slightly  in  water.  Nerve  Sedative, 
Antispasmodic.  Dose:  5  to  10  grains  (0.3  to  0.65  Gm.). 

BROMINE. 

Bromum,  N.  F.  Br.  Heavy,  dark  brownish-red  liquid,  evolv- 
ing reddish  fumes  highly  irritating  to  eyes  and  lungs;  peculiar, 
suffocating  odor;  sp.  gr.  about  3.016.  1  mil  (Cc.)  dissolves  in 
about  90  mils  water;  freely  soluble  in  alcohol,  ether,  chloro- 
form. Caustic  (pure),  Antiseptic  Inhalant  (1:500  water); 
used  chiefly  technically.  Antidotes:  ammonia  by  inhalation; 
sodium  carbonate,  albumen.  Must  be  kept  in  cool  place  and 
handled  with  great  care.  Its  vapor  is  very  irritating  to  mucosae. 

BROMIPIN. 

Bromine  addition  products  of  fatty  acids  of  sesame  oil.  Yel- 
low, oily  liquids;  10  and  33J/3  per  cent,  bromine,  respectively. 
Nervine.  Dose:  10  percent.,  1  to  4  fluidrachms  (4  to  15  mils 
[Cc.]);  33|/$  percent.,  20  to  60  minims  (1.3  to  4  mils  [Cc.]). 

BROMOFORM. 

Bromoformum ;  Formyl  Tribromide;  Tribromomethane.  CHBr3- 
Heavy  liquid;  ethereal  odor,  chloroform-like  taste.  Sp.  gr. 
2.595  to  2.620.  Miscible  with  chloroform,  alcohol,  ether,  oils; 
soluble  in  80  parts  glycerin;  very  slightly  in  water.  Anti- 
spasmodic  and  Sedative,  chiefly  in  whooping-cough.  Average 
Dose:  3  minims  (0.2  mil  [Cc.]),  in  hydroalcoholic  solution 
or  emulsion.  Antidotes:  atropine  or  strychnine  hypodermically ; 
amyl  nitrite  or  ammonia  by  inhalation;  oxygen.  Bromoform 
is  so  extremely  volatile  that  the  vials  are  liable  to  lose  in 
weight  rapidly  on  keeping.  It  is  hence  best  ordered  in  small 
quantities,  and  should  be  kept  in  cool  place  protected  against 
light. 

BROMURAL. 

Monobromisovalerylurea.  White,  almost  tasteless  needles.  Sol- 
uble readily  in  hot  water,  ether,  alcohol  or  alkalies.  Nerve 
Sedative,  Hypnotic.  Dose:  5  to  10  grains  (0.3  to  0.65  Gm.). 

BROOM    TOPS.     See    Scoparius. 

BROVALOL. 

Bornyl  Bromovalerate.  Colorless,  oily,  faintly  aromatic  liquid; 
25.2  percent,  bromine.  Soluble  in  alcohol,  chloroform  or  ether; 
insoluble  in  water.  Analeptic,  Nerve  Sedative.  Dose;  4  to  12 
grains  (0.25  to  0.75  Gm.),  in  capsules. 


This  house  supplies  only  one  quality  of  each  product:  that  best 
suited  to  the  purposes  intended.  The  specification  "Squibb's" 
is  not  open  to  various  interpretations ;  it  has  a  plain,  posi- 
tive meaning.  Therefore,  when  prescribing,  specify  SQUIBB'S. 


34         SQUIBB'S  MATERIA  MEDICA 

BRYONIA. 

Bryonia,  N.  F.;  Bryony.  Dried  root  of  Bryonia  alba  or  B. 
dioica  (Fam.  Cucurbitaceat).  Drastic  Resinous  Cathartic;  used 
in  dropsies,  pleurisy,  etc.  Average  Dose:  1  Gm.  (15  grains). 
(See  also  Fluidextract;  Tincture.) 

Buchu,   Squibb  tin,  lb.        ;  1 4  lb. 

Bnchii.  Dried  leaves  of  Barosma  beiullna  (Short  Buchu)  or  of 
B.  serratifolia  (Long  Buchu).  (Fam.  Rulacece).  The  article 
here  listed  is  short  buchu  of  best  quality;  in  odor,  taste,  and 
other  characteristics  satisfying  the  most  exacting  requirements. 
Diuretic,  Anticatarrhal;  chiefly  in  diseases  of  bladder  and 
kidneys.  Average  Dose:  30  grains  (2  Gm.).  (See  also  Fluid- 
extract;  Tablets  [Part  II].). 

BuCKBEAN.  See  Menyanthes. 

BUCKTHORN  BARK.     See  Frangula. 

BUCKTHORN  BERRIES. 

Rhamnus  Caiharlica,    N.    F.      Dried,    ripe    fruit    of    Rhamnus 

calhartica  (Fam.     Rhamnacete).       Purplish-black     externally; 

faint,   unpleasant   odor;    sweetish,    then    nauseating,   bitter   taste. 

Cathartic.  Average  Dose:  15  grains  (I  Gm.). 

BURDOCK.     See  Lappa. 

Burow's  Solution.         See  Solution  Aluminum  Acetate. 

BUTTERNUT  BARK.     See   Juglans. 

CACAO.     See  Cocoa. 

Cacao   Butter.      See   Oil   Theobroma. 

CACTUS  CRANDIFLORUS. 

Cactus  Crandiflorus,  N.  F.;  Night-blooming  Cereus.  Fresh 
succulent  stems  of  wild-growing  Cactus  grandiflorus  (Cereus 
grandiflorus;  Fam.  Cociacece).  Used  in  neurotic  heart  distur- 
bances; value  doubted  by  many. 

Cadmium  Iodide   Reagent.       See  Reagents  (Part  IV). 

Cadmium. Potassium  Iodide  Reagent. 

See  Reagents  (Part  IV). 

Cadmium  Sulphate  Reagent.        See  Reagents  (Part  IV). 

0  Caffeine,   Squibb  carton,  oz. 

Caffeina;  Coffeine;  Theine;  Guaranine;  Trimethylxanthine. 
CsHioO;>N4.H:>O.  Base  from  leaves  of  Thea  sinensis  (Fam. 
Ternsircemlaceai),  or  dried  seeds  of  Coffea  arabica  (Fam.  Ru- 
biacece).  White,  silky,- bitter  needles;  efflorescent  in  dry  air.  1 
Gm.  dissolves  in  46  mils  (Cc.)  water,  66  alcohol,  5.5  chloroform, 
530  ether.  Aqueous  solubility  increased  by  potassium  bromide, 
sodium  benzoate,  sodium  salicylate.  Diuretic;  Cardiac,  Res- 
piratory and  Psychic  Stimulant.  Average  Dose:  2]/2  grains 
(0.15  Gm.).  See  also  Tablets  [Part  II].) 


SQUIBB'S  MATERIA  MEDICA         35 

©  Caffeine  Citrated,  Squibb  bottle,  oz. 

Caffeina  Citraia.  Unstable  compound  of  caffeine  and  citric 
acid,  containing  when  dried  48  percent,  anhydraus  caffeine. 
White,  odorless  powder;  of  slightly  bitter,  acid  taste.  Soluble 
in  about  25  parts  water,  in  mixture  of  equal  volumes  chloro- 
form and  alcohol.  Average  Dose:  5  grains  (0.3  Gm.).  (See 
also  Tablets  [Part  II].) 

CAFFEINE  CITRATED,  GRANULAR  EFFERVESCENT. 

Caffeina  Cilrata  Effervescens.  4  percent,  official  citrated  caf- 
feine. Average  Dose:  60  grains  (4  Gm.). 

Caffeine  Hydrobromide,  Squibb 

bottle,  oz.          ;  J/g-oz.  vial 

CgHioN4O2.HBr.2H2O.  Large,  white  crystal*,  turning  red- 
dish on  exposure.  Soluble  in  water,  with  decomposition. 

0  Caffeine  and  Sodium  Benzoate,  Squibb 

bottle,  oz.          ;  J/g-oz.  vial 

Caffeina  SoJio-Benzoas.  Newly  official.  White,  odorless, 
slightly  bitter  powder;  assays  when  dried  46  to  50  percent, 
anhydrous  caffeine.  1  Gm.  dissolves  in  1  .'1  mils  (Cc.)  water, 
some  caffeine  separating  on  standing;  in  30  mils  alcohol.  Car- 
diac, Respiratory  and  Psychic  Stimulant.  Average  Dose : 
hypodermically,  3  grains  (0.2  Gm.)  ;  per  os,  5  grains  (0.3  Gm.) 

Caffeine  Sodio=Salicylate,  Squibb 

bottle,  oz.          ;  |/g-oz.  vial 

Caffeins  Sodio-Salicylas,  N.  F.  White,  odorless,  slightly  bitter 
powder,  containing  about  50  percent,  caffeine.  1  Gm.  dissolves 
in  about  2  mils  (Cc.)  water.  Cardiac  Stimulant, 
Analgesic;  used  mainly  hypodermically,  in  rheumatism  com- 
plicated with  heart  disease,  and  in  threatening  collapse.  Aver- 
age Dose:  3  grains  (0.2  Gm.).  (See  also  Ampuls.) 

Cajuputol.        See   Eucalyptol. 
CALABAR  BEAN.     See  Physostigma. 

CALAMINE,  PREPARED. 

Calamina  Prceparala,  N.  F.;  Lapis  Calaminaris.  Native  zinc 
carbonate,  calcined;  or  calcined  zinc  carbonate  containing  small 
amount  ferric  oxide.  Fine,  pink,  odorless,  tasteless  powder. 
Insoluble  in  ordinary  solvents.  Protective,  Siccative  Dermic. 

Calcium  Acetate.  See  list  of   Reagent   Chemicals,   under 

Reagents   (Part   IV). 


The  prices  of  the  Squibb  Products  are  in  all  instances  as  low  as 
the  quality  and  quantity  of  ingredients  and  the  expense  of  man- 
ufacture allow.  They  include  containers,  packing  and  boxing.  When 
ordering  or  prescribing  medicinal  products,  specify  SQUIBB'S. 


36         SQUIBB'S  MATERIA  MEPICA 

Calcium  Bromide,  Squibb  bottle,  Ib.         ;  oz. 

Calcii  BromiJum.  CaBr2-2HoO;  not  anhydrous  salt  formerly 
official.  White,  granular,  odorless;  sharp,  saline  taste;  very 
deliquescent.  1  Gm.  dissolves  in  0.7  mil  (Cc.)  water,  1 .3 
mils  alcohol;  insoluble  in  chloroform  or  ether.  Nerve  Seda- 
tive, similar  to  but  more  irritant  than  sodium  bromide. 
Average  Dose:  15  grains  (1  Gm.).  Keep  well  stoppered,  in 
dry  place. 

Calcium  Carbonate  Precipitated.       See  Chalk  Precipitated. 
Calcium  Carbonate  Reagent.        See  Reagents  (Part  IV). 

®  Calcium  Chloride,  Squibb 

bottle,  Ib.          ;  '/4  Ib.          ;  oz. 

Calcii  ChloriJum.  Hydrated  form,  containing  about  2  mole- 
cules crystal  water  and  assaying  not  less  than  75  percent.  Ca  Clo. 
White,  hard,  odorless  fragments  or  granules;  sharp,  saline  taste; 
very  deliquescer.t.  1  Gm.  dissolves  in  0.62  mil  (Cc.)  water, 
10  alcohol;  insoluble  in  ether.  Used  as  Hemostatic  and  An- 
tipruritic,  internally,  as  Antiphlogistic  externally;  in  chronic 
itching  hemorrhagic  conditions,  uticaria,  serum  rashes,  etc. 
Average  Dose:  8  grains  (0.5  Gm.).  Incompatible  with  solu- 
ble carbonates,  phosphates  and  sulphates,  producing  corre- 
sponding insoluble  salts  of  calcium.  Keep  well  stoppered  in 
dry  place.  (See  also  Reagents  [Part  IV].) 

Calcium  Qlycerophosphate,  Squibb 

bottle,  Ib.          ;  %  Ib.          ;  oz. 

Calcii  Clycerophosphas.  C3H,-,(OH)1>PO|Ca.  Newly  of- 
ficial. White,  odorless,  almost  tasteless,  slightly  hygroscopic 
powder.  1  Gm.  dissolves  in  about  50  mils  (Cc.)  water;  citric 
acid  increases  solubility.  Used  as  Nerve  Tonic,  especially  in 
neurasthenia;  generally  in  combination  with  other  glycero- 
phosphates.  Average  Dose:  4  grains  (0.25  Gm.)  Solutions  do 
not  keep  well;  1  minim  chloroform  to  fluidounce  retards  change. 
Use  cold,  sterile,  distilfed  water  only.  (See  also  Tablets  [Part 
II].) 

Calcium  Hypophosphite,  Squibb 

bottle,  Ib.  ;  '/J  Ib.  ;  oz. 

Calcii  Hypophosphis.  Ca^^PCXj)::.  White  prisms,  scales  or 
crystalline  powder;  nauseous,  bitter  taste.  1  Gm.  dissolves  in 
6.5  mils  (Cc.)  water;  insoluble  in  alcohol.  Used  as  general 
reconstructive  tonic,  largely  in  tuberculosis,  usually  in  com- 
bination with  other  hypophosphites.  Average  Dose:  8  grains 
(0.5  Gm.).  NOTE:  Caution  should  be  observed  in  dispensing 
this  salt  as  explos.on  is  liable  to  occur  when  it  is  triturated  or 
heated  with  nitrates,  chlorates  or  other  oxidizing  agents. 


SQUIBB'S  MATERIA  MEDICA         37 

0  Calcium  Lactate,  Squibb 

bottle,  Ib.         ;  14  lb.         '•  oz- 

Calcii  Lactas.  Ca(C3H5O3) 2.  5H2O.  Newly  official.  White, 
odorless,  nearly  tasteless  granules.  1  Gm.  dissolves  in  20  mils 
(Cc.)  water;  almost  insoluble  in  alcohol.  Alterative,  Anti- 
cachectic;  latterly  also  Hemostatic,  in  conditions  referable  to 
defective  blood  coagulability,  in  operations  about  nose  and  throat 
to  prevent  postoperative  hemorrhage,  and  in  such  blood  dyscra- 
sias  as  boils,  urticaria,  hemoglobinuria,  etc.  Has  characteristic 
action  of  calcium;  less  irritating  and  hence  better  adapted 
to  hypodermic  use  than  calcium  chloride.  Average  Dose  (ace. 
to  U.  S.  P.)  :  8  grains  (0.5  Gm.)  ;  other  authorities  advise  1 5 
to  20  grains  (1  to  1 .3  Gm.)  an  hour  before  meals  in  solution. 
Incompatible  with  soluble  carbonates,  phosphates  and  sulphates, 
producing  corresponding  insoluble  salts  of  calcium. 

Calcium  Lactophosphate  Soluble,  Squibb 

bottle,  Ib.          ;  %  Ib.          ;  oz. 

Calcii  Laclophosphas,  N.  F.  Granular  combination  of  calcium 
lactate  and  calcinm  phosphate.  Soluble  in  water;  almost  in- 
soluble in  alcohol.  Alterative,  Anticachectic;  similar  to  cal- 
cium lactate,  but  not  adapted  to  hypodermic  use. -Average  Dose : 
8  grains  (0.5  Gm.). 

CALCIUM   MONOIODOEEHENATE.    See  Sajodin. 

Calcium  Oxide.         See  Lime. 

Calcium  Oxide  Reagent.       See  Reagents  (Part  IV). 

Calcium  Phenolsulphonate,  Squibb 

bottle,  Ib.          ;  %  lb.          ;  oz. 

Calcium  Sulphocarbolate.  An  exceptionally  fine  article,  free 
from  sulphates,  chlorides  and  metallic  impurities.  Readily 
soluble  in  water.  Used  as  Intestinal  Antiseptic.  Dose : 
2  to  5  grains  (0.13  to  0.3  Gm.),  in  solution  or  tablets. 

Calcium  Phosphate  Precipitated,  Squibb      carton,  lb. 

Calcii  Phosphas  Prcecipilatus,  N.  F.  Dropped  from  U.  S.  P. 
Caa(PO4);>.  White,  bulky,  odorless,  tasteless  powder;  insol- 
uble in  water  and  alcohol.  Reconstructive,  like  calcium  sails 
in  general;  in  malnutrition,  rickets,  osteomalacia,  etc.  Also 
Reagent.  Average  Dose:  15  grains  (1  Gm.). 


If  difficulty  is  experienced  in  procuring  any  Squibb  product, 
in  the  original  packages  here  listed,  please  notify  us;  we 
shall  see  that  your  wants  are  met  promptly  and  satisfactorily. 


38         SQUIBB'S  MATERIA  MEDICA 

Calcium   Sulphide   Crude,   Squibb 

bottle,  Ib.         ;  %  Ib.         ;  oz. 

Calcii  Sulphidum  Crudumj  formerly  officially  called  Sulphur- 
ated Lime.  Not  less  than  55  percent.  CaS.  Pale-gray  or 
yellowish  powder;  hydrogen-sulphide  odor;  nauseous,  alkaline 
taste.  Gradually  decomposes  on  exposure  to  moist  air.  Slightly 
soluble  in  water;  insoluble  in  alcohol.  Antipyic,  Alterative;  in 
boils,  scrofula,  phthisis,  etc.  Also  Depilatory.  Average  Doge: 
I  grain  (0.065  Gm.).  Keep  well  stoppered.  (See  also  Tab- 
lets  [Part  II].) 

CALCREOSE. 

Loose  chemical  combination  of  equal  parts  creosote  and  lime. 
Dark-brown  powder;  empyreumatic  odor;  sharp,  phenolic  taste. 
Form  of  creosote.  Dose:  5  to  15  grains  (0.3  to  I  Gm.). 

Calendula,  Squibb  ,  tin,  Ib. 

Calendula,  N.  F.;  Marigold.  Dried  ligulate  florets  of  Calen- 
dula officinalis  (Fam.  Composites).  Used  externally,  as  mild 
Irritant. 

Calisaya  Bark.        See   Cinchona. 
Calomel.         See   Mercury  Chloride,   Mild. 

CALOMELOL. 

Colloidal  Calomel.  Whitish-gray,  odorless,  tasteless  powder; 
80  percent,  calomel,  20  percent,  proteins.  With  water  it  forms 
an  opalescent  suspension;  insoluble  in  alcohol  or  ether;  precipi- 
tated by  acids  from  its  solutions,  redissolved  by  alkalies.  In- 
compatible with  soluble  hydroxides,  carbonates,  iodides  a»d 
oxidizing  agents.  Succedaneum  for  calomel  internally  and  ex- 
ternally, in  same  doses  and  strengths.  Calomelol  Ointment  con- 
tains 20  percent,  mercury  as  calomelol. 

Calumba,   Squibb         Ground   for  Percolation  tin,  Ib. 

Calumba;  Columbo.  Dried  root  of  Jaleorhiza  palmala  (Fam. 
Menispermaces).  Simple  Bitter,  Stomachic.  Average  Dose: 
30  grains  (2  Gm.).  (See  also  Fluidextract;  Tincture.) 

CAMPHO-MENTHOL.     See   Menthol   Camphorated. 

®  CAMPHOR. 

C 'amphora ;  Gum  Camphor.  CioHiflO.  Ketone  obtained  from 
Cinnamomum  Camphora  (Fam.  Lauracece).  Sp.  gr.  0.990. 
Very  volatile.  Freely  soluble  in  alcohol,  chloroform,  ether, 
oils;  slightly  soluble  in  water.  Readily  pulvenzable  in  pres- 
ence of  little  alcohol,  ether  or  chloroform.  Stimulant,  Ana- 
leptic,  Antispasmodic,  Antipruritic,  Rubefacient;  in  collapse, 
flatulence,  cramps,  spasmodic  cough,  asthma,  neuralgia,  etc. 
Average  Dose:  by  mouth,  3  grains  (0.2  Gm.).;  hypodermic, 
]]/2  grains  (0.1  Gm.).  (See  also  Ampuls;  Spirit.) 


SQUIBB'S  MATERIA  MEDICA         39 

Camphor  Monobromated,  Squibb 

*  Crystals  or  Powdered  bottle  ;  14  lb.  ;  oz. 
Camphora  Monobromaia;  Bromcamphor.  CioHisOBr.  Bro- 
mine substitution  product  of  camphor.  Colorless  needles  or 
scales,  of  mild  camphoraceous  odor  and  taste.  Almost  insol- 
uble in  water.  I  Gm.  dissolves  in  6.5  mils  (Cc.)  alcohol,  0.5 
chloroform,  1 .6  ether.  Sedative,  Antispasmodic,  Antineuralgic, 
Average  Dose:  2  grains  (0.13  Gm.). 

CANELLA. 

Canella,  N.  F.  Dried  inner  bark  of  Canella  Winierana  (Fam. 
Canellaceai) .  Cinnamon-like  odor;  warm  aromatic  taste. 
Aromatic  Bitter,  Corrigent.  Average  Dose:  30  grains  (2  Gm.). 

CANNABIS. 

Canella,  N.  F.  Dried  inner  bark  of  Canella  Winlerana  (Fam. 
saliva  or  of  variety  indica  (Fam.  Moraces).  Physiological 
assay  required  by  U.  S.  P.  Sedative,  Anodyne.  (See  also 
Extract;  Fluidextract;  Tincture.) 

®  Cantharides  Powdered,  Squibb  tin,  %  Jb. 

Cantharis;  Spanish  Flies.  The  thoroughly  dried  beetle  Canlharis 
vesicaloria.  Best  Russian  beetle,  assaying  at  least  0.6  percent, 
cantharidin,  as  officially  demanded.  Rubefacient  and  Vesi- 
cant externally;  Genito-urinary  Irritant  internally.  Antidotes: 
flaxseed  tea,  opium  per  rectum,  morphine  subcutaneously.  Oils 
should  be  avoided.  (See  also  Cerate;  Collodion;  Liniment; 
Tincture.) 

Capsicum.         See    Pepper,   Red. 

CARAMEL. 

Caramel,  N.  F.;  Burnt  Sugar  Coloring.  Concentrated  aqueous 
solution  of  product  obtained  by  heating  sugar  or  glucose  until 
the  sweet  taste  is  destroyed  and  a  uniform  dark-brown  mass 
results,  a  little  alkali  being  added  while  heating.  Thick  liquid, 
odor  of  burnt  sugar;  pleasant,  bitter  taste;  sp.  gr.  about  1.35. 
Mixes  clearly  with  water,  diluted  alcohol.  Coloring  agent. 

CARAWAY. 

Carum;  Caraway  Seed.  Dried  fruit  of  Carum  Carvi  (Fam. 
Umbelliferas').  Aromatic  Carminative;  Condiment.  Average 
Dose:  15  grains  (1  Gm.). 

Carbon   Disulphide  Reagent.       See  Reagents  (Part  IV). 
Carbon  Tetrachloride  Reagent.       See  Reagents  (Part  IV). 


The  Squibb  products  are  recognized  everywhere  as  the  Quality 
Standard.  They  are  of  uniform  purity  and  strength,  hence 
theraupeutically  dependable.  When  ordering  or  prescribing  medi- 
cinal products,  you  will  do  well  always  to  specify  SQUIBB'S. 


40         SQUIBB'S  MATERIA  MEDICA 

0  Cardamom  Seed,  Squibb 

*  Whole  tin,  lt>.         ;   1/4  Ib. 

Ground  for  Percolation  tin,  Ib. 

Cardamomi  Semen.  Dried  seeds  of  Eleitaria  CarJamomum 
(Fam.  Zingiberacea) .  Free  from  twigs,  leaves  and  other 
portions  of  plant,  possessing  a  characteristic,  agreeably  aromatic 
odor  and  taste,  yielding  less  than  officially  permitted  quan- 
tity of  ash.  Carminative,  Corrective;  Flavor.  Average  Dose: 
15  grains  (1  Gm.).  (See  also  Fluid;  Fluidextract;  Tincture.) 

Cardamom  Compound,  Squibb 

Ground  for  Percolation  tin,  Ib. 

Mixture  of  cardamom,  Saigon  cinnamon,  caraway  and  cochi- 
neal, intended  for  preparation  of  Tincture  Cardamom  Com- 
pound. 

CARCENTOS. 

Colloidal  Silver  Oxide.  50  percent.  Ag.  Odorless,  tasteless 
black,  shining  scales.  Forms  colloidal  suspension  with  water 
or  glycerin.  Antiseptic  Astringent,  in  5  to  25  percent,  sus- 
pensions or  10  percent,  dusting  powder. 

CARMINE. 

Carminum,  N.  F.  Aluminum  lake  of  coloring  principle  of 
cochineal.  Irregular,  bright  red,  odorless,  tasteless  fragments. 
Soluble  freely  in  ammonia  water  and  alkaline  liquids,  slightly 
in  water.  Red  coloring. 

CARRAGEEN.    See  Chondrus. 

0  Cascara  Sagrada,  Squibb 

Whole  carton,  Ib. 

*  Ground  for  Percolation  tin,  Ib. 

Cascara  Sagrada ;  Sacred.  Bark.  Dried  bark  of  trunk  and 
branches  of  Rhamnus  Purshiana  (Fam.  Rhamnacece)  thor- 
oughly seasoned.  In  its  selection  it  is  carefully  differentiated 
from  barks  of  allied  species.  Being  the  best  procurable  and 
well  seasoned,  preparations  made  from  it  are  of  maximum 
efficacy.  Laxative,  acting  mainly  on  colon;  has  but  little 
tendency  to  produce  secondary  constipation.  Average  Dose : 
15  grains  (1  Gm.).  (See  also  Extract;  Fluid;  Fluidextract. 
Tablets  [Part  II].) 

CASCARILLA. 

Cascarilla,  N.  F.;  Sweet  Bark.  Dried  bark  of  Croton  Elu- 
teria  (Fam.  jEup/iorfciacece) .  Clove-like  odor;  warm,  aromatic, 
bitter  taste.  Aromatic  Bitter,  like  gentian.  Average  Dose : 
30  grains  (2  Gm.). 

Cassia.      See   Cinnamon,    Cassia. 


^QUIBB'S  MATERIA  MEDICA          41 

CASSIA  FISTULA. 

Cassia  Fislula,  N.  F.;  Purging  Cassia.  Dried  fruit  of  Calhar- 
tocarpus  Fistula  (Fam.  Leguminous).  Laxative,  similar  to 
Senna.  Average  Dose:  60  grains  (4  Cm.). 

CASTANEA. 

Caslanea,  N.  F.;  Chestnut  Leaves.  Dried  leaves  of  Costarica 
Jentata  (Fam.  Fagacece).  Astringent  but  used  mainly  in 
whooping  cough.  Average  Dose:  60  grains  (4  Cm.).  (See 
also  Fluidextract.) 

Cataplasm  Kaolin,  Squibb        special  tins,  Ib.         ;  J/2  Ib. 

Cataplasma  Kaolini,  N.  F.;  Kaolin  Poultice.  Dropped  from 
U.  S.  P.  Consists  of  kaolin,  boric  acid,  thymol,  methyl  salicyl- 
ate,  oil  peppermint  and  glycerin.  A  very  smooth;  homogen- 
ous mass,  free  from  gnttiness  and  irritating  properties,  each 
of  the  ingredients  being  of  selected  quality. 

CATECHU.        See  Gambir. 

CATNEP. 

Cataria,  N.  F.;  Catmint.  Dried  leaves  and  flowering  tops  of 
Nepela  Cataria  (Fam.  Labiata),  Aromatic,  mint-like  odor, 
bitter,  pungent,  aromatic  taste.  Aromatic  Carminative,  simi- 
lar to  peppermint.  Average  Dose :  60  grains  (4  Gm.). 

CAULOPHYLLUM. 

Caulophyllum,  N.  F.;  Blue  Cohosh.  Dried  rhizome  and  roots 
of  Caulophyllum  ihalictroides  (Fam.  Berberidacea) .  Asserted 
Diuretic  and  Emmenagogue.  Average  Dose:  8  grains  (0.5 
Gm.). 

Caustic    Potash.         See  Potassium  Hydroxide. 
Caustic  Soda.         See  Sodium  Hydroxide. 

CELERY    FRUIT. 

Apii  Fructus,  N.  F.;  Celery  Seed.  Ripe  fruit  of  Apium 
Craveo/ens  (Fam.  Umbellifera).  Agreeable  odor;  aromatic, 
warm  taste.  Domestic  Emmenagogue.  Average  Dose :  30 
grains  (2  Gm.).  (See  also  Fluidextract.) 

CENTAURY. 

Centaurium,  N.  F.  Dried  flowering  plant  of  Erylhrtea  Cen- 
taurium  (Fam.  Gentianacece).  Faint  odor;  persistently  bitter 
taste.  Bitter  Stomachic,  similar  to  gentian.  Average  Dose : 
30  grains  (2  Gm.). 


Since  we  make  only  one  quality  of  each  product,  that  best 
suited  to  the  purposes  intended,  the  specification  "Squibb's" 
is  not  open  to  various  interpretations,  but  has  a  plain,  positive 
meaning.  When  ordering  or  prescribing,  specify  SQUIBB'S. 


42          SQUIBB'S  MATERIA  MEDICA 

Cerate,  Squibb  jar,  lb. 

Ceratum;  Simple  Cerate.  Made  from  white  wax  and  ben- 
zoinated  lard,  modified  as  necessary  for  use  in  southern  latitudes 
or  during  the  hot  season,  by  replacing  a  portion  of  the  ben- 
zoinated  lard  by  white  wax.  The  several  ingredients  are  all 
of  pharmacopceial  quality.  Emollient,  base  for  cerates. 

Cerate,   Blistering.       See  Cerate  Cantharides. 

CERATE    CAMPHOR. 

Ceratum  Camphors,  N.  F.;  Camphorated  Ointment  or  Cerate. 
Dropped  from  U.  S.  P.  Contains  10  percent,  camphor  lini- 
ment, equivalent  to  2  percent,  camphor,  in  combination  of  white 
wax  7  parts,  white  petrolatum  3  and  benzoinated  lard  8.  Anti- 
septic and  Antipruritic. 

®  Cerate  Cantharides,  Squibb  tin,  lb.        ;  14  lb. 

Ceratum  Canlharidis;  Blistering  Cerate.  100  Gm.  represent  35 
Gm.  best  Russian  cantharides,  extracted  with  oil  turpentine  and 
a  little  acetic  acid.  As  the  active  principle  of  cantharides  is 
not  soluble  in  water,  a  very  thin  film  of  water  upon  the 
skin  will  prevent  blistering  effect  of  the  cerate.  Therefore  the 
skin  should  be  thoroughly  cleansed  before  applying.  Soap 
and  water  are  usually  effective,  but  frequently  it  is  necessary 
to  resort  to  diluted  acetic  acid  or  vinegar,  which  not  only 
removes  the  excretions  from  the  skin,  but  is  an  excellent  sol- 
vent of  the  active  principle  of  cantharides. 

CERATE  LEAD  SUBACETATE. 

Ceratum  Plumbi  Subacetalis,  N.  F.;  Goulard's  Cerate;  Lead 
Cerate.  Combination  of  solution  lead  subacetate  20  percent., 
camphor  2  percent.,  with  wool- fat,  white  wax  and  white  petro- 
latum. Astringent,  in  inflammatory  cutaneous  lesions. 

CERATE    ROSIN. 

Ceralum  Resin  re ;  Basilicon  Ointment.  Combination  of  rosin 
35  parts,  lard  50,  wax  15.  Antiphlogistic,  Discutient;  to 
"draw." 

Cerate  Rosin  Compound,  Squibb  jar,  lb. 

Ceraium  Resince  Composilum,  N.  F.;  Deshler's  Salve.  Drop- 
ped from  U.  S.  P.  Combination  of  rosin  45  parts,  yellow  wax 
45,  suet  60,  turpentine  23,  linseed  oil  27.  Antiphlogistic,  Dis- 
cutient; in  external  inflammations,  to  "draw." 

Cerium  Oxalate,  Squibb  carton         ;  %  lb.        oz. 

Cen'i  Oxalas.  Natural  mixture  of  oxalates  of  cerium,  didy- 
mium,  lanthanum,  and  other  associated  elements.  The  chem- 
ical formula  cannot  therefore  be  stated.  White  or  pinkish- 
white,  odorless,  tasteless  powder,  insoluble  in  ordinary  solvents. 
Gastric  Sedative;  in  vomiting  of  pregnancy,  seasickness,  etc. 
Average  Dose:  3  grains  (0.2  Gm.).  (See  also  Tablets 

CETACEUM.     See  Spermaceti. 
[Part  H].) 


SQUIBB'S  MATERIA  MEDICA         43 

©  Chalk   Precipitated,    Squibb  carton,  Ib. 

CaCOg.  Particularly  acceptable  for  pharmaceutical  purposes, 
dentifrices,  etc.  Nearly  insoluble  in  water;  insoluble  in  alcohol. 
Carbonic  acid  and  ammonium  salts  increase  aqueous  solubility. 
Antacid.  Average  Dose:  15  grains  (1  Gm.).  Offered  in 
three  densities;  Light,  Medium,  and  Heavy.  On  unspecified 
orders  the  medium  grade  is  supplied.  Write  for  quotations  on 
bulk  quantities. 

CHALK  PREPARED. 

Creia  Pr&paraia;  Drop  Chalk.  CaCOs.  Differs  from  pre- 
cipitated chalk,  in  that  it  is  a  native  calcium  carbonate  freed 
from  most  of  its  impurities  by  elutriation.  White  to  grayish- 
white,  odorless,  tasteless  powder.  Insoluble  in  the  ordinary 
solvents.  Antacid.  Average  Dose:  15  grains  (1  Gm.). 

Chamomile,    German.      See    Matricaria. 
CHANNING'S  SOLUTION 

See  Solution  Mercury  and  Potassium  Iodide. 
CHAPMAN'S  MIXTURE.     See  Mixture  Copaiba  and  Opium. 
0  Charcoal  Powdered,   Squibb       bottle,  Ib.        ;  %  Ib. 

Carbo  Ligni.  C.  Soft-wood  charcoal,  offered  in  fine  powder. 
Antizymotic,  Absorbent;  in  flatulent  dyspepsia,  fetid  breath, 
etc.  Average  Dose:  15  grains  (1  Gm.).  (See  also  Tablets 
and  Troches  [Part  II].) 

CHEMICAL    FOOD.      See    Syrup    Phosphates    Compound. 

CHESTNUT  LEAVES.    See  Castanea. . 

CHIMAPHILA. 

Chimaphila,  N.  F.;  Pipsissewa.  Dried  leaves  of  Chimaphila 
umbellala  (Fam.  Ericacea).  Formerly  used  as  Tonic,  As- 
tringent, Diuretic.  Average  Dose:  30  grains  (2  Gm.). 

CHINOSOL. 

Oxyquinoline  Sulphate.  Yellow  powder;  saffron  odor; 
astringent,  aromatic  taste.  Readily  soluble  in  water;  sparingly 
in  alcohol;  insoluble  in  ether.  Antiseptic  (1:500  to  1:3000 
solution),  Antizymotic.  Dose:  3  to  5  grains  (0.2  to  0.3  Gm.). 
Incompatible  with  lead  acetate,  mercuric  chloride,  iron  salts,  etc. 

CHIONANTHUS. 

Chionanthus,  N.  F.;  Fringe  Tree  Bark.  Dried  bark  of  root  of 
Chionanlhus  virginica  (Fam.  Oleacea).  Characteristic  odor; 
bitter  taste.  Used  as  Alterative  and  Aperient.  Average  Dose: 
30  grains  (2  Gm.). 


The  founder  of  the  House  of  Squibb,  Dr.  Edward  R.  Squibb, 
not  only  had  high  ideals,  but  lived  and  labored  for  them;  and, 
in  the  words  of  William  Miller  Bartlett,  "the  House  of  Squibb 
stands  today  as  a  living  monument  to  the  honor,  integrity,  zeal 
and  devotion  of  its  founder." 


44         SQUIBB'S  MATERIA  MEDICA 

CHIRATA. 

Chirala,  N.  F.;  Chiretta.  Dried  plant  of  S&erlia  Chlra^ila 
(Fam.  Geniianaced),  Bitter  Stomachic,  similar  to  gentian. 
Average  Dose:  15  grains  (1  Cm.). 

Chloral  Camphorated,  Squibb  bottle,  oz. 

Chloralum  Camphor  alum,  N.  F.  Equal  parts  chloral  and  cam- 
phor, liquefied.  Transparent,  colorless,  oily  liquid.  Soluble  in 
alcohol,  ether,  oils;  insoluble  in  water.  Topical  Anodyne,  in 
neuralgia,  toothache,  etc. 

ChIoramine=T,  Squibb  bottle,  6^/3  ozs.  ;  582  grs. 

,  Sodium  Para-Toluenesulfonchloramine.  CH3.C6H4.SOoNa:- 
NC1.3Hi>O.  White  powder;  slight  chlorous  odor.  Soluble  in 
water;  insoluble  in  oils.  Introduced  by  Drs.  Carrel,  Dakin  and 
colleagues  as  a  water-soluble  Germicide  and  Wound  Disinfec- 
tant acting  much  like  the  hypochlorites  but  being  less  irritating 
and  more  stable.  Used  chiefly  in  1  or  2%  solutions;  in  nose 
and  throat  in  Y^%  solution.  (See  next  title,  and  Tablets 
[Part  II]  ;  also  Dichloramine-T  and  Halazone  Tablets.) 

Chloramine=T   Surgical    Paste,    Squibb 

jar,  Ib.          '.  /4  lb.          ;  2  ozs. 

A  white,  odorless  paste,  of  "vanishing  cream"  type.  Contains 
1%  chloramine-T  (Dakin),  combined  with  a  neutral  base 
(sodium  stearate)  according  to  formula  of  Dr.  Alexis  Carrel. 
Introduced  by  Drs.  Carrel,  Dakin  and  colleagues  as  Germicide 
and  Wound  Disinfectant. 

®  Chloral  Hydrate  Crystals,  Squibb        g.  s.  bottle,  oz. 

Chloralum  HyJraium.  CoHCIgO.HjO.  Colorless,  transparent, 
rhomboidal  crystals;  aromatic,  penetrating  odor;  bitterish,  caus- 
tic tasle.  1  Gm.  dissolves  in  0.25  mil  (Cc.)  water,  1 .3  al- 
cohol, 2  chloroform,  1.5  ether;  very  soluble  in  olive  oil;  sol- 
uble also  in  glycerin.  Hypnotic,  Antispasmodic,  Analgesic; 
also  Reagent.  Contramdicated  in  gastritis  and  fafty  heart. 
Its  continued  administration  is  liable  to  produce  a  habit. 
Average  Dose:  8  grains  (0.5  Gm.),  well  diluted.  Absorbed 
very  quickly  (5  to  10  minutes).  Liquefies  when  triturated  with 
about  an  equal  quantity  camphor,  menthol,  thymol,  or  phenol. 
Antidotes:  cocaine,  atropine  oY  strychnine,  hypodermically; 
-stimulants;  oxygen  or  amyl  nitrite  by  inhalation.  Incom- 
patible with  alkalies  and  alkali  carbonates.  NOTE:  When 
kept  in  cork-stoppered  bottles  Chloral  Hydrate  is  liable  to  be- 
come discolored,  from  chemical  action  on  the  cork.  Unless 
otherwise  specified,  we  supply  it  only  in  glass-  stoppered  bottles. 
Because  of  its  volatility  it  should  be  kept  carefully  stoppered, 
in  a  cool  place. 


SQUIBB'S  MATERIA  MEDICA          45 

CHLORAZENE.     Brand   of   Chloramine-T. 

CHLORBUTANOL. 

Acetone-Chloroform;  Chloretone.  White,  volatile  crystals; 
camphoraceous  odor  and  taste.  Soluble  in  alcohol,  chloroform, 
glycerin,  oils;  in  about  125  parts  water.  Local  Anesthetic,  Seda- 
tive, Antiseptic.  Dose:  5  to  20  grains  (0.3  to  i.3  Gm.). 
Used  locally  in  saturated  aqueous  solution. 

Chlorcosane,  Squibb  bottle,  pint,        ;  %  pint 

Chlorinated  Paraffin.  New  oil-solvent  for  Dicbloramine-T, 
devised  by  Drs.  Dakin  and  Dunham.  Bland,  tasteless,  yellow, 
non-irritant,  non-toxic,  stable  oil,  which  will  hold  8  to  10  per 
cent.  Dichloramine-T  in  solution.  To  prepare  solutions,  warm 
Chlorcosane,  stir-in  Dichloramine-T  until  dissolved,  filter  if  de- 
sired (usually  not  necessary),  and  cool  to  suitable  temperature 
for  use.  For  wounds,  2  to  5  percent,  solutions  of  Dichloramine- 
T  are  used,  in  nose  and  throat  1  percent,  or  weaker  applied  with 
swab,  director  or  atomizer.  While  Chlorcosane  solutions  of 
Dichloramine-T  keep  for  quite  some  time  they  should  be  dis- 
carded if  they  contain  a  precipitate  that  does  not  disappear  on 
gently  warming. 

CHLORETONE.     Brand   of   Chlorbutanol. 

0  Chloroform,  Squibb      For  Anesthesia. 

Ib.          ;  Y2  Ib.          ;  |4  Ib.          ;  2  ozs.          ;  oz. 
Dropping  Ampul  50  Gm.         ;  25  Gm. 

Chloroformum ;  Formyl  Trichloride.  CHCls.  Made  and 
purified  in  the  Squibb  Laboratories  by  a  process  yielding  a 
product  above  pharmacopoeial  requirements;  contains  less  than 
1  percent,  of  alcohol,  and  is  free  from  chlorides,  free  chlorine, 
chlorinated  pyrogenous  compounds,  and  all  impurities  decom- 
posable by  sulphuric  acid.  Chloroform  is  soluble  in  about 
210  times  its  volume  of  water,  miscible  with  alcohol,  ether, 
benzin  and  oils.  Sp.  gr.  1.474  to  1.478.  General  Anaesthetic; 
Analgesic,  Antispasmodic.  Used  also  pharmaceutically  and 
as  Reagent.  Average  Dose:  (by  mouth)  5  minims  (0.3  mil 
[Cc.]),  dissolved  in  elixir;  avoid  water.  Antidotes:  If  venous 
engorgement  of  head  and  neck  exists,  artificial  respiration 
(Schasfer's  method).  If  cerebral  anemia  exists,  inversion  of 
patient,  artificial  respiration  while  inverted.  Always  first 
empfy  the  lungs  of  vapor.  Atropine  or  camphor  hypodermi- 
cally;  amyl  nitrite  or  ammonia  by  inhalation.  Caution:  Chloro- 
form vapor  decomposes  on  contact  with  a  flame  or  white-hot 

The  Squibb  Ideals  have  taken  concrete  form  in  the  Squibb 
Products;  these  are  universally  recognized  as  standards  of 
uniform  Purity  and  Efficacy,  that  is,  general  Excellence  and 
Reliability.  Specify  SQUIBB'S  when  prescribing  or  ordering. 


46         SQUIBB'S  MATERIA  MEDICA 

©  Chloroform,  Squibb  (Cont.) 

solids;  chlorine,  hydrochloric  acid  gas,  phosgene  and  other 
intensely  irritating  products  being  produced.  Therefore,  chlo- 
roform should  not  be  administered  by  artificial  light  unless 
the  flames  or  wires  are  protected  by  a  closed  case.  Heaters 
(grates,  stoves,  electric,  etc.)  should  have  all  glowing  surfaces 
enclosed.  Always  provide  for  the  rapid  escape  from  the 
room  of  all  decomposition  products.  NOTE.  Chloroform  is  not 
to  be  relied  upon  for  anaesthesia  after  the  container  has  been 
opened  and  the  product  exposed  to  the  air  for  some  time. 

CHONDRUS. 

ChonJrus;  Irish  Moss;  Carrageen.  Dried  plant  of  ChonJrus 
crispus  or  of  Gigarlina  mamillosa  (Fam.  Cigartinacets). 
Demulcent,  Lubricant. 

©  CHROMIUM  TRIOXIDE. 

Chromil  TrioxiJum;  so-called  .Chromic  Acid;  Chromic  Anhy- 
dride. CrOg.  Small,  dark  purplish-red  crystals,  deliquescent 
in  moist  air.  1  Gm.  dissolves  in  0.6  mil  (Cc.)  water;  de- 
composed by  organic  solvents.  Caustic,  Astringent;  in  ulcers, 
hypertrophic  coryza,  sweating  feet,  etc.,  as  5  to  20  percent, 
aqueous  solution.  Antidotes:  magnesia  or  chalk;  demulcents. 
Because  of  its  activity  as  an  oxidizing  agent,  great  caution 
should  be  observed  in  bringing  it  into  contact  with  organic 
substances,  such  as  alcohol,  ether,  glycerin,  cork,  tannic  acid, 
sugar  and  collodion.  Disregard  hereof  is  liable  to  result  in 
dangerous  accident. 


Chromium  Trioxide  Reagent.     See  Reagents  (Part  IV). 

©  CHRYSAROBIN. 

Chrysarobinum ;  often  erroneously  called  Chrysophanic  Acid. 
Mixture  of  neutral  principles  extracted  from  goa  powder. 
Brownish  to  orange  powder;  tasteless,  odorless;  irritating  to 
mucous  membranes.  1  Gm.  dissolves  in  385  mils  (Cc.)  alcohol, 
12.5  chloroform,  16  ether;  very  slightly  soluble  in  water.  Anti- 
parasitic,  Afltiseptic,  in  6  percent,  ointment,  in  psoriasis,  tri- 
chophytosis,  alopecia  areata,  etc.  Poisonous.  No  special  anti- 
dotes known. 

CIMICIFUGA. 

Cimicifuga;  Black  Cohosh;  Black  Snakeroot;  Macrotys. 
Dried  rhizome  and  roots  of  Cimicifuga  racemosa  (Fam.  Ranun- 
culacece).  Used  as  Alterative,  Sedative,  Emmenagogue;  in 
rheumatism,  chorea,  hysteria,  dysmenorrhea,  etc.  Average 
Dose:  15  grains  (1  Cm.). 


SQUIBB'S  MATERIA  MEDICA         47 

0  Cinchona,  Squibb 

Ground  for  Percolation  tin,  Ib. 

Cinchona;  Calisaya  Bark;  Yellow  Cinchona.  Dried  bark  of 
Cinchona  Ledgeriana,  C.  Calisaya,  and  of  hybrids  of  these 
(Fam.  Rubiacece).  Special  car*  is  observed  in  the  selection 
to  insure  botanical  authenticity.  Assays  not  less  than  5  percent, 
alkaloids.  Antiperiodic,  Bitter  Tonic.  Average  Dose:  15 
grains  (1  Gm.).  (See  also  Extract;  Fluidextract.) 

Cinchona  Compound  Ground,  Squibb 

For  Percolation  tin,  Ib. 

Mixture  of  5  parts  red  cinchona,  4  parts  bitter  orange  peel, 
and  1  part  serpentaria,  for  preparing  Tincture  Cinchona  Com- 
pound. 

0  Cinchona,   Red,   Squibb 

*  Ground  for  Percolation  tin,  Ib. 

Powdered  tin,  Ib.         ;  !4  Ib. 

Cinchona  Rubra;  Red  Bark;  Red  Peruvian  Bark.  Dried  bark 
of  Cinchona  succirubra  or  its  hybrids  (Fam.  Rubiaceai),  assay- 
ing not  less  than  5  percent,  alkaloids.  Uses  and  dose,  as  cin- 
chona. (See  also  Fluid;  Fluidextract;  Tincture.) 

Cinchonidine  (Alkaloid),  Squibb  bottle,  oz. 

CigH22ON2.  Alkaloid  from  cinchona.  White  crystals.  Sol- 
uble in  alcohol,  chloroform,  dilute  acids;  slightly  in  ether; 
insoluble  in  water.  Bitter  Tonic,  Antiperiodic,  like  quinine. 
Dose:  tonic,  1  to  2  grains  (0.065  to  0.13  Gm.),  in  pills  or 
syrup;  antiperiodic,  15  grains  (1  Gm.),  between  paroxysms. 

Cinchonidine  Salicylate,  Squibb  bottle,  oz. 

CigHosONo.CyHoOs.  Colorless,  microscopic  crystals  or 
needles.  Soluble  readily  in  alcohol,  sparingly  in  water.  Anti- 
periodic,  Antirheumatic;  chiefly  in  subacute  ^and  chronic  rheu- 
matism. Dose:  15  to  30  grains  (1  to  2  Gm.)  per  day. 

Cinchonidine  Sulphate,  Squibb 

bottle,  oz.          ;  tin,  5  ozs.,  per  oz. 

CinchoniJina:  Sulphas.  (Ci9H22ON2)2  H2SO4.2H2O.  White, 
glistening,  odorless,  very  bitter  needles  or  prisms.  1  Gm.  dis- 
solves in  65  mils  (Cc.)  water,  90  alcohol,  620  chloroform; 
nearly  insoluble  in  ether.  Antiperiodic,  Bitter  Tonic,  like 
quinine.  Average  Dose:  2x/2  grains  (0.15  Gm.). 


The  Squibb  Label  on  a  package  is  a  positive  guaranty  for  the 
uniform  Purity  and  Reliability  of  the  product.  We  make  only 
ONE  quality:  the  SQUIBB  quality;  and  our  prices  are  as  low 
as  they  can  be  made  for  that  quality.  Specify  SQUIBB'S. 


48          SQUIBB'S  MATERIA  MEDICA 

Cinchonine  Sulphate,  Squibb 

bottle,  oz.          ;  tin,  5  ozs.,  per  oz. 

Cmchomna:  Sulphas.  (CwH^ON^o  H2SO4.2Hoq.  White, 
odorless,  bitter  crystals  or  prisms.  I  Gm.  dissolves  in  60  mils 
(Cc.)  water,  12.5  alcohol,  47  chloroform,  3230  ether.  Anti- 
periodic,  Bitter  Tonic.  Average  Dose:  2^2  grains  (0.15  Gm.). 

Cineol.        See  Eucalyptol. 

Cinnabar,  Artificial.        See  Mercury  Sulphide  Red. 

Cinnamon,   Cassia,  Squibb 

Powdered  tin,  lb. 

sprinkler-top  tins,  4  ozs.,  per  doz.          ; 
2  ozs.,  per  doz.          ;  1  oz.,  per  doz. 

Cassia  Bark;  Chinese  Cinnamon.  Inner  bark  of  Cinnamomum 
Cassia.  Aromatic,  Carminative;  also  used  in  perfumery  and 
as  flavoring.  Ordinary  Dose:  4  grains  (0.25  Gm.). 

Cinnamon,   Ceylon,   Squibb 

Powdered  tin,  lb. 

sprinkler-top  tins,  4  ozs.,  per  doz. 

2  ozs.,  per  doz.          ;  1  oz.,  per  doz. 

Cinnamomiim  Zeylanicum.  Dried  inner  ,bark  of  cultivated  trees 
of  Cinnamomum  Ze\>lan:cum  (Fam.  Lauraceai).  It  is  collected 
by  stripping  the  bark  from  the  shoots'  and  collecting  it  in 
bundles.  It  is  then  allowed  to  remain  in  this  state  for  a 
while,  to  undergo  fermentation,  which  makes  the  subsequent 
process  of  removing  the  outer  bark  more  easy.  1  he  bark 
then  contracts,  curling  up  into  quills,  which  are  wrapped  around 
each  other,  the  smaller  inside,  until  six  or  eight  layers  are 
formed.  Cassia  bark  is  generally  found  less  tightly  curled 
up  and  each  quill  separate.  It  is  redder  and  darker,  and  has 
a  s'.ronger  but  less  pleasant  odor.  It  is  also  rougher  than 
Ceylon. 

©Cinnamon,    Saigon,   Squibb 

Ground  fdV  Percolation  tin,  lb.         ;  14  lb. 

*  Powdered  tin,  lb. 

sprinkler-top  tins,  4  ozs.,  per  doz. 

2  ozs.,  per  doz.  ;  1  oz.,  per  doz. 

Cinnamomum  Saigonicum.  Bark  of  an  undetermined  species  of 
Cinnamomum  (Fam.  Lauracece).  Same  action  and  uses  as 
Cassia  cinnamon. 

Cinnamon,    Sumatra,    Squibb  tin,  lb. 

(Powdered)  sprinkler-top  tins,  4  ozs.,  per  doz. 

2  ozs.,  per  doz.  ;  1  oz.,  per  doz. 

A  high-quality  Cinnamon  of  exquisite  flavor  and  superior 
strength,  practically  equalling  in  these  respects  the  more  costly 
Saigon  cinnamon. 


SQUIBB'S  MATERIA  MEDICA         49 

Citrine  Ointment.        See  Ointment  Mercury  Nitrate. 
CLEMENS'  SOLUTION.     See  Solution  Arsenic,  Clemens*. 

0  Clove,   Squibb     *  Whole  tin,  Ib. 

Powdered  tin,  lb. 

sprinkler-top  tins,  4  ozs.,  per  doz.          ; 
2  ozs.,  per  doz.          ;  1  oz.,  per  doz. 

Caryophyllus.  Dried  flower-buds  of  Eugenia  aromalica  (Fam. 
Mjjr/acece).  Cloves  are  cultivated  in  the  West  Indies,  Guiana, 
Cayenne,  Sumatra,  and  Zanzibar,  the  Molucca  Islands  having 
been  for  a  long  time  the  chief  source  of  the  best  clove's.  The 
buds  are  at  first  white,  then  green  and  finally  red,  when  they 
are  immediately  picked  and  dried  by  solar  heat.  The  best 
cloves  are  large,  dark,  brittle,  and  exude  oil  on  being  scratched. 
The  grade  quoted  is  prime  quality  of  most  careful  selection, 
and  not  deprived  of  any  of  its  oil.  Condiment;  Aromatic, 
Carminative,  Counter-irritant.  Average  Dose:  4  grains  (0.25 
Gm.). 

COAGULEN. 

Extract  from  blood  platelets,  with  milk  sugar.  1  Gm.  repre- 
sents 20  Gm.  dried  blood.  Yellowish,  granular  powder;  slight 
odor;  sweet  taste.  Freely  soluble  in  water.  Coagulant,  Hemo- 
static;  usually  in  5  percent,  solution,  locally,  or  by  intramuscular 
or  intravenous  injection.  (See  also  Thromboplastm.) 

COAL  TAR. 

Pix  Lilhanlhracis,  N.  F.;  Pix  Carbonis.  Obtained  as  by- 
product in  destructive  distillation  of  coal.  Nearly  black,  thick 
liquid  or  semisolid;  naphthalene-like  odor;  sharp,  burning  taste. 
Soluble  in  chloroform,  benzene;  slightly  soluble  in  water;  par- 
tially soluble  in  alcohol.  Antiseptic,  Antiparasitic. 

Cobalt  Chloride  Reagent.       See  Reagents    (Part  IV). 
Cobalt   Nitrate  Reagent.        See  Reagents   (Part   IV). 

t  0  Cocaine   (Alkaloid),   Squibb  ]/g-oz.  vial 

Cocaina;  Methylbenzoylecgonine.  C]7H2iO4N.  Alkaloid 
obtained  from  coca.  Colorless  prisms;  slightly  bitter  taste,  pro- 
ducing on  tongue  temporary  numbness.  1  Gm.  dissolves  in 
about  600  mils  (Cc.)  water,  6.5  alcohol,  0.7  chloroform,  3.5 
ether,  12  olive  oil;  soluble  in  liquid  petrolatum.  Nerve  Stim- 
ulant, Local  Anesthetic,  Mydriatic.  Average  Dose :  1/4  grain 
(0.015  Gm.).  Antidotes:  tannin,  emetics;  chloral  hydrate: 
amyl  nitrite  by  inhalation;  morphine  or  caffeine  hypodermically ; 
stimulants. 


This  house  supplies  only  one  quality  of  each  product:  that  best 
suited  to  the  purposes  intended.  The  specification  "Squibb's" 
is  not  open  to  various  interpretations;  it  has  a  plain,  posi- 
tive meaning.  When  prescribing,  please  specify  SQUIBB'S. 


50         SQUIBB'S  MATERIA  MEDICA 

t0C«caine   Hydrochloride,  Squibb  J/fc-oz.vial 

Large  or  *  Small  Crystals 

Cocaines  Hydrochloridum.  Ci7H2iO4N.HCI.  Colorless  prisms, 
flaky  leaflets,  or  a  white,  crystalline,  permanent  powder;  slightly 
bitter  taste,  and  producing  on  tongue  a  tingling,  followed  by 
numbness.  1  Gm.  dissolves  in  0.4  mil  (Cc.)  water,  3.2  alcohol, 
12.5  chloroform;  soluble  in  glycerin;  insoluble  in  ether.  Local 
Anesthetic,  Nasal  Astringent  and  Mydriatic,  externally;  Anti- 
emetic  and  Cerebral  Stimulant,  internally.  Used  in  1  to  4  per- 
cent, solution  on  mucous  membranes,  in  0.2  to  1  percent,  solu- 
tion hypodermically.  Average  Dose:  %  grain  (0.015  Gm.). 
(See  also  Tablets  [Part  II].).  NOTE.  Solutions  of  cocaine  hy- 
drochloride  after  being  kept  long  are  partly  hydrolyzed;  they 
cannot  be  sterilized  by  boiling  without  some  loss,  but  amount 
of  decomposition  is  ordinarily  insignificant. 

COCCULUS  INDICUS. 

Cocculus  Indicus,  N.  F.  Dried  fruit  of  Anamirla  Cocculus 
(Fam.  Menispermacece).  Parasiticide. 

Cochineal,  Squibb        Powdered  tin,  Ib.         ;  %  Ib. 

Coccus;  Coccionella.  Dried  female  insect,  PseudocoCcus  cacti 
(Fam.  Cocci  dee).  Of  best  quality,  and  very  satisfactory  tinc- 
torial power.  Its  coloring  matter  is  soluble  in  water,  alcohol, 
or  ammonia  water;  insoluble  in  oils,  slightly  soluble  in  ether. 

COCHINEAL   COLOR. 

Liquor  Cocci,  N.  F.  6.5  Gm.  cochineal  in  100  mils  (Cc.), 
with  potassium  carbonate,  alum,  potassium  bitartrate,  glycerin, 
alcohol,  water.  Red  coloring. 

COCILLANA. 

Cocillana,    N.    F.       Dried    bark  of     Cuarea    Rusbyi     (Fam. 

Me/iacece).      Characteristic    odor,  astringent,    nauseating    taste. 

Nauseant  Expectorant,  similar  to  ipecac.  Average  Dose:  15 
grains  (I  Gm.). 

COCOA. 

Cacao  Prceparata,  N.  F.;  Soluble  Cocoa.  Powdered  roasted 
kernels  of  ripe  seeds  of  Theobroma  Cacao  (Fam.  Sterculiaceee) . 
Beverage  and  Flavor. 

f0  Codeine   (Alkaloid),  Squibb  1/8-oz.vial 

Codeina;  Methylmorphine.  CisHoiOaN.H^O.  An  alkaloid 
of  opium,  but  usually  obtained  from  morphine  by  methylation. 
White,  odorless,  faintly  bitter  crystals.  1  Gm.  dissolves  in  120 
mils  (Cc.)  water,  2  alcohol,  0.5  chloroform,  18  ether.  Seda- 
tive, Analgesic,  Hypnotic,  Sedative;  in  coughs,  pains,  mor- 
phinism, etc.  Less  constipating  and  less  apt  to  induce  habit  than 
morphine.  Average  Dose :  J/g  grain  (0.03  Gm.).  (See  also 
Tablets  [Part  II].) 


SQUIBB'S  MATERIA  MEDICA          51 

•{•Codeine  Hydrochloride,  Squibb  J/g-oz.  vial 

Ci8H2iO3N.HC1.2H2O.  Small,  white  needles.  Soluble  in 
about  20  parts  water.  Action  and  dose,  like  codeine  alkaloid. 

f  Codeine  Nitrate,  Squibb  J/g-oz.  vial 

Action  and  dose  like  codeine  alkaloid. 

f  0  Codeine  .  Phosphate,  Squibb  j/8-oz.  vial 

Codeina  Phosphas.  Ci8H2iO3N.H3PO4.2HoO.  Fine,  white, 
odorless,  bitter  needles  or  powder.  I  Gm.  dissolves  in  2.3  mils 
(Cc.)  water,  325  alcohol,  4500  chloroform,  1875  ether.  Pre- 
ferred for  subcutaneous  use.  Average  Dose:  1/2  grain  (0.03 
Gm.).  (See  also  Tablets  [Part  II].) 

t  ©  Codeine  Sulphate,  Squibb  J/s-oz.  vial 

*Crystals  or  Powdered 

Codeines  Sulphas.  (CisHsiOsNh.HoSO^SHoO.  Long,  glis- 
tening, white,  efflorescent,  odorless,  bitter  needles  or  prisms,  or 
powder.  1  Gm.  dissolves  in  about  30  mils  (Cc.)  water,  1280 
alcohol;  insoluble  in  ether  or  chloroform.  Uses  and  dose  same 
as  codeine.  (See  also  Tablets  [Part  II].) 

Colchicine,  Squibb  5-gr.  vial 

Colchicina.  CosHonOf.N.  Alkaloid  from  colchicum.  Pale- 
yellow  leaflets  or  powder,  darkening  on  exposure  to  light,  of 
peculiar  odor  and  very  bitter  taste.  1  Gm.  dissolves  in  22 
mils  (Cc.)  water,  220  ether;  freely  soluble  in  alcohol  or  chloro- 
form. Antipodagric,  Antineuralgic,  Alterative;  in  gout,  rheu- 
matism, sciatica,  asthma,  etc.  Average  Dose :  1/i28  grain  (0.0005 
Gm.),  two  or  three  times  daily.  Antidotes:  tannin,  emetics; 
opiates;  strong  coffee  and  other  stimulants.  (See  also  Tablets" 
[Part  II].) 

COLCHICUM  CORM. 

Colchici  Cormus;  Colchicum  Root.  Dried  corm  of  Colchicum 
autumnale  (Fam.  Liliaceet),  Assays  not  less  than  0.35  per- 
cent, colchicme.  Antmeuralgic,  Alterative;  chiefly  in  gout. 
Average  Dose:  4  grains  (0.25  Gm.).  (See  also  Fluidextract.) 

®  COLCHICUM  SEED. 

Colchici  Semen.  Dried  seeds  of  Colchicum  autumnale.  Assays 
not  less  than  0.45  percent,  colchicme.  Action  as  of  colchicum 
root.  Average  Dose:  3  grains  (0.2  Gm.).  (See  also  Fluid- 
extract;  Tincture;  Wine.) 


The  prices  of  the  Squibb  Products  are  in  all  instances  as  low  as 
the  quality  and  quantity  of  ingredients  and  the  expense  of  man- 
ufacture allow.  They  include  containers,  packing  and  boxing.  When 
ordering  or  prescribing  medicinal  products,  specify  SQUIBB'S. 


52          SQUIBB'S  MATERIA  MEDICA 

Cold  Cream,  Squibb  glass  jar,  1  Ib.          ;  3  ozs., 

1-oz.  collapsible  tubes,  per  doz. 

This  product  has  been  added  to  our  list  in  response  to  repeated 
demands  from  physicians.  A  superior  product  delicately  per- 
fumed, and  safe  to  use  wherever  cold  cream  is  required. 
Perfectly  harmless  and  free  from  irritating  ingredients,  hence 
may  be  freely  applied  even  to  the  most  tender  skin.  Does  not 
cause  growth  of  hair;  does  not  become  rancid  on  keeping. 

Cold  Cream  Benzoinated.     See  Benzoinated  Cream. 

COLLARGOL. 

Colloidal  Silver;  Argentum  Crede.  "  Black,  crystalline  sub- 
stance. Soluble  in  20  parts  water.  Systemic  Disinfectant,  An- 
tipyic;  largely  intravenously  or  rectally  in  septicemia,  pyemia, 
puerperal  sepsis,  etc.;  internally  in  infectious  gastric  and  intesti- 
nal diseases;  externally  in  !/5  to  '  percent,  solution  in  pus 
cavities,  etc.,  and  as  1 5  percent,  ointment  (Unguentum  Crede) 
by  inunction  in  mild  septicemia  and  in  local  infections.  Dose: 
1  to  2  grains  (0.065  to  0.13  Gm.)  every  12  hours. 

COLLODION,  BLISTERING.     See  Collodion,  Cantharidal. 

COLLODION,  CANTHARIDAL. 

Collodium  Cantharidatum ;  Blistering  or  Vesicant  Collodion. 
Represents  60  percent,  cantharides  extracted  with  acetone  and 
a  little  glacial  acetic  acid,  in  flexible  collodion.  The  skin 
must  be  thoroughly  cleansed  (with  vinegar,  preferably)  and 
dried  before  applying  this  collodion,  as  the  active  principle  of 
cantharides  is  not  soluble  in  water.  If  this  precaution  is  not 
observed,  there  is  danger  of  failure  to  secure  the  full  vesicating 
action.  Keep  well  stoppered,  away  from  flame.  Inflammable! 

0  Collodion  (Contractile),  Squibb 

bottle,  Ib.          ;  J/4  Ib.          ;  oz.  vials,  per  doz. 

Collodium.  Each  100  mils  contains  4  Gm.  pyroxylin  dissolved 
in  mixture  of  alcohol  (1)  and  ether  (3).  Employed  for  draw- 
ing together  the  edges  of  incised  wounds  and  for  covering 
abraded  surfaces.  Incompatible  with  liquefied  carbolic  acid  and 
water.  Keep  well  stoppered,  away  from  flame.  Inflammable! 

COLLODION,   CORN'.     See   Collodion   Salicylic   Compound. 

COLLODION  CROTON  OIL. 

Collodium  Tiglii,  N.  F.  10  percent,  croton  oil.  Counter- 
irritant. 


SQUIBB'S  MATERIA  MEDICA          53 

©  Collodion,   Flexible,   Squibb        bottle,  lb.         ;  |4  lb. 

oz.  vials  with  glass  rods,  in  cartons,  doz. 

J/2-oz.  vials  with  glass  rods,  in  cartons,  doz. 

Colloaium  Flexile;  Liquid  Court  Plaster.  We  have  deviated 
somewhat  from  U.  S.  P.  formula  for  sake  of  greater  efficiency 
and  reliability.  The  product  here  listed  contains  6  percent, 
pyroxylin  and  5  percent,  castor  oil,  as  against  4.85  percent, 
and  3  percent,  respectively  in  official  article,  and  the  camphor 
has  been  omitted,  because  unnecessary.  Being  somewhat  thicker 
than  is  customary,  it  gives  a  more  satisfactory  film.  It  may 
be  distinguished  from  the  cheaper  and  less  satisfactory  collo- 
dions of  the  market  by  its  excellent  odor  and  its  freedom  from 
acetone,  amyl  acetate,  wood  alcohol  and  other  less  expensive 
solvents  which  are  frequently  employed.  This  Liquid  Court 
Plaster  may  be  used  in  all  cases  where  ordinary  court  plaster  is 
employed  and  where  an  impervious  covering  is  desired.  Easy 
of  application,  and  hygienic;  its  flexible  nature  prevents  it 
from  cracking  or  becoming  detached;  the  film  produced  is  al- 
most invisibles  Keep  in  cool  place,  and  from  lights  and  fire. 

COLLODION  IODINE. 

ColloJium  lodi,  N.  F.  5  percent,  iodine,  in  flexible  collodion. 
Discutient,  Antipruritic ;  employed  principally  in  chilblains. 

COLLODION  IODOFORM. 

Collodiam  lodoformi,  N.  F.  5  percent,  iodoform,  in  flexible 
collodion. 

Collodion,  Salicylic  Compound,  Squibb 

bottle,  lb.  ;  14  lb. 

oz.  vials  with  glass  rods,  in  cartons,  per  doz.  ; 

J/2-oz.  vials  with  glass  rods,  in  cartons,  per  doz. 

Essentially  ColloJium  Salicylicum  Compositum,  N.  F.,  but  made 
with  contractile  collodion,  which  is  better  for  the  purpose  in- 
tended than  flexible  collodion  as  called  for  in  N.  F.  formula. 
Aside  from  the  collodion  base,  it  contains  salicylic  acid  and 
fluidextract  cannabis.  Corn  Cure. 

COLLODION,  STYPTIC. 

ColloJium  Styplicum,  N.  F.  Contains  20  percent  tannic  acid 
in  flexible  collodion.  Styptic;  for  wounds  which  have  been 
partly  closed  by  stitches,  and  for  bleeding  and  ulcerated  sur- 
faces. Keep  in  a  cool  place,  remote  from  lights  and  fire. 


jf  difficulty  is  experienced  in  procuring  any  Squibb  product, 
in  the  original  packages  here  listed,  please  notify  us;  we 
shall  see  that  your  wants  are  met  promptly  and  satisfactorily. 


54         SQUIBB'S  MATERIA  MEDICA 

®  COLOCYNTH. 

Colocynthls;  Colocynth  (Bitter  Apple)  Pulp.  Dried  pulp  of 
fruit  of  Citrullus  Colocynlhis  (Fam.  Cucurbitacece) .  Drastic 
Hydragogue  Cathartic;  rarely  used  alone.  Average  Dose:  I 
grain  (0.065  Gm.).  (See  also  Extract.) 

COLOGNE.     See  Spirit,  Perfumed. 

COLTSFOOT. 

Farfara,  N.  F.  Dried  leaves  of  Tussilago  Farfara  (Fam. 
Composi/te).  Faint  odor;  mucilaginous,  bitter  taste.  Demul- 
cent Expectorant.  Average  Dose:  60  grains  (4  Gm.). 

Columbo.         See  Calumba. 

Compound  Alum  Powder.  See  Powder  Alum  Compound. 

CONDURANGO. 

ConJurango,  N.  F.  Dried  bark  of  MarsJenia  Condurango 
(Fam.  Asclepiadacece).  Bitter  Stomachic,  introduced  especial- 
ly for  cancer  cachexia.  Average  Dose:  60  grains  (4  Gm.). 
(See  also  Fluidextract.) 

CONFECTION  ROSE. 

Confeclio  Rosae,  N.  F.  Red  rose  '','aves  8  parts,  sugar  64 
parts,  clarified  honey  12  parts  and  shonger  rosewater  16  parts. 
Pill  excipient. 

Confection   Senna,   Squibb  jar,  lb.         ;  %  Ib. 

This  confection  enjoys  a  reputation  for  therapeutic  efficiency  of 
many  years'  standing,  and  is  reliable  as  an  effective  Cathartic, 
especially  in  convalescence  after  child-birth.  It  contains  senna 
(10  percent.),  coriander,  cassia  fistula,  tamarind,  prune,  and  fig, 
with  sugar  and  some  water.  Slightly  different  from  N.  F. 
Confeclio  Senna.  Average  Dose:  60  grains  (4  Gm.). 

CONIUM. 

Conium,  N.  F.  Hemlock;  Poison  Hemlock.  Dried,  full-grown, 
unripe  fruit  of  Conium  maculaium  (Fam.  Umbelliferai).  Assays 
not  less  than  0.5  percent,  coniine.  Deteriorates  rapidly  and  is 
wholly  unfit  for  use  after  two  years.  Antispasmodic,  Sedative, 
Antineuralgic.  Average  Dose :  3  grains  (0.2  Gm.).  (See  also 
Fluidextract.) 

Consumptive's  Weed.       See  Yerba  Santa. 

CONVALLARIA    FLOWERS. 

CortvallaricB  Flores,  N.  F.;  Lily  of  the  Valley  Flowers.  Dried 
inflorescence  of  Convallaria  majalis  (Fam.  Liliaces).  Odor 
agreeable;  taste  sweetish,  then  slightly  acrid.  Cardiac  Tonic, 
similar  to  digitalis.  Average  Dose:  8  grains  (0.5  Gm.). 


SQUIBB'S  MATERIA  MEDICA          55 

CONVALLARIA  ROOT. 

ConvallaricE  Radix,  N.  F.;  Lily  of  the  Valley  Root.  Dried 
rhizome  and  rootlets  of  Convallaria  majalls  (Fam.  Liliacece). 
Heart  Tonic,  similar  to  digitalis.  Average  Dose:  8  grains 
(0.5  Gm.). 

0COPAIBA. 

Copaiba;  Copaiva;  Balsam  Copaiba.  Oleoresin  from  South 
Anverican  species  of  Copaiba  (Fam.  Leguminosee).  Pale 
yellow  to  brownish-yellow,  viscid  liquid;  peculiar,  aromatic 
odor;  bitter,  acrid  taste.  Insoluble  in  water;  partly  soluble  in 
alcohol ;  completely  soluble  in  chloroform  or  ether.  Sp.  gr. 
0.940  to  0.995.  Anticatarrhal,  Diuretic,  Expectorant,  mainly 
im  gonorrhea,  cystitis,  chronic  bronchitis,  etc.  Average  Dose: 
15  minims  (1  mil  [Cc.]). 

0  Copper  Sulphate,   Squibb 

Crystals  bottle,  Ib.         ;  V4  Ib. 

*  Granular  bottle,  Ib.         ;  %  Ib. 

Cupri  Sulphas;  Cupric  Sulphate;  Blue  Vitriol;  Blue  Stone. 
CuSO-j.SHoO.  An  exceptionally  pure  product;  free  from  alumi- 
num and  heavy  metals.  Large,  deep-blue,  odorless,  efflorescent 
crystals,  or  greenish-blue  granular  powder,  of  nauseous,  metallic 
taste.  1  Gm.  dissolves  in  2.5  mils  (Cc)  water,  500  alcohol,  2.8 
glycerin.  Escharotic,  Astringent,  Emetic,  Nervine;  externally 
in  eye  diseases,  hypendrosis,  bleeding,  etc.;  internally  in  ner- 
vous diseases  and  to  produce  vomiting.  Average  Dose :  astrin- 
gent and  nervine,  i/6  grain  (0.01  Gm.)  ;  emetic,  4  grains  (0.25 
Gm.).  Incompatible  with  fixed  alkalies  and  alkali  carbonates; 
with  iodides,  mercury  bichloride,  sodium  borate,  lead  acetate, 
silver  nitrate,  and  with  tannin-containing  infusions,  tinctures, 
etc.  Antidotes:  milk  and  sugar,  or  white  of  egg  freely;  pure 
potassium  ferrocyanide,  10  to  15  grains  (0.65  to  1  Gm.).  (See 
also  Reagents  [Part  IV];  Tablets  [Part  II].) 

COPTIS. 

Copiis,  N.  F.;  Gold  Thread.  Dried  plant  of  Coptis  irifolia 
(Fam.  Ranunculacecz) .  Faint  odor;  bitter  taste.  Bitter 
Stomachic,  similar  to  gentian.  Average  Dose :  30  grains 
(2  Gm.). 

CORDIAL,    GODFREY'S.     See    Mixture    Opium    and    Sassafras. 
CORDIAL,  NEUTRALIZING.     See  Mixture  Rhubarb  Alkaline. 


The  Squibb  products  are  recognized  everywhere  as  the  Quality 
Standard.  They  are  of  uniform  purity  and  strength,  hence 
therapeutically  dependable.  When  ordering  or  prescribing  med- 
icinal products,  you  will  do  well  always  to  specify  SQUIBB'S. 


56         SQUIBB'S  MATERIA  MEDICA 

CORIANDER. 

Coriandrum;  Coriander  Seed.  Dried  ripe  fruit  of  Coriandrum 
saiivum  (Fam.  Umbelliferas).  Aromatic,  Carminative,  Cor- 
rective of  action  of  drastic  purgatives.  Average  Dose:  8  grains 
(0.5  Gm.). 

•  •* 

CORN   SILK.     See  Zea. 

CORNUS. 

Cornus,  N.  F.;  Dogwood  Bark.  Dried  bark  of  root  of  Cornus 
florida  (Fam.  Cornaceee) ;  slight  odor;  bitter,  astringent  taste. 
Used  as  Astringent,  Antiperiodic.  Average  Dose :  30  grains 
(2  Gm.). 

CORNUTOL.      Brand   name    for   aqueous   fluidextract   ergot. 

CORPUS  LUTEUM,  DRIED. 

From  cow's  or  pig  s  ovaries.  Alterative,  in  disorders  following 
menopause,  obesity  with  dysmenorrhea,  etc.  Dose :  */2  to  1 
grain  (0.03  to  0.065  Gm.)  two  or  three  times  daily. 

Corrosive   Sublimate.         See    Mercury    Chloride,    Corrosive. 

CORYDALIS. 

Corydalis,  N.  F.;  Turkey  Corn.  Dried  tubers  of  Bicuculla 
canadensis  (Fam.  Fumariaceae).  Nearly  odorless;  slightly 
bitter.  Formerly  used  as  Antiluetic,  but  now  considered  useless 
by  scientific  practitioners.  Average  Dose:  10  grains  (0.65  Gm.). 

CORYFIN. 

Ethylglycolic  Acid  Ester  of  Menthol.  Colorless,  oily  liquid, 
of  faint  menthol  odor.  Soluble  in  alcohol,  ether,  chloroform, 
oils;  sparingJy  soluble  in  water.  Local  Anodyne  and  Anti- 
catarrhal.  Applied  pure  or  with  olive  oil. 

COTARNINE  HYDROCHLORIDE. 

Cotarninat  Hydrochloridum ;  Stypticin.  Newly  official. 
Ci^Hi^NOgCl.  Salt  of  base  obtained  by  hydrolyzing  narco- 
tine.  Yellow,  bitter,  odorless  powder.  Very  soluble  in  water, 
alcohol.  Used  as  Uterine  Hemostatic  and  Sedative,  internally; 
Styptic,  externally.  Average  Dose :  1  grain  (0.065  Gm.). 

GOTO.     See  Paracoto. 

COTTON,  ABSORBENT. 

Cossppium  Purificatum ;  Purified  Cotton.  Hairs  of  seed  from 
cultivated  varieties  of  Gossypium  herbaceum  (Fam.  Malvaceae). 

COTTON,  STYPTIC. 

Gossypium  Stypticum,  N.  F.  Absorbent  cotton  impregnated 
with  dilute  solution  ferric  chloride. 


SQUIBB'S  MATERIA  MEDICA          57 

COTTON- ROOT  BARK. 

Gossypii  Cortex,  N.  F.  Dried  bark  of  root  of  Gossypium 
herbaceum  (Fam.  Malvaceae)  and  other  species  of  Gossyplum. 
Used  as  Emmenagogue.  Average  Dose:  30  grains  (2  Gm.). 
(See  also  Fluidextract.) 

COUCH-GRASS.     See  Triticum. 

COUMARIM. 

Coumarinam,  N.  F.  Anhydride  of  ortho-oxycinnamic  acid, 
occurring  in  tonka,  melilot,  etc.,  or  prepared  synthetically. 
Colorless  crystals;  fragrant  odor;  bitter,  aromatic,  burning 
taste.  Freely  soluble  in  alcohol,  ether,  chloroform,  oils; 
sparingly  soluble*  in  water.  Flavoring. 

CRAMP   BARK.     See  Viburnum   Opulus. 
CRANESBILL.     See  Geranium. 
Cream  of  Tartar.    •     See  Potassium  Bitartrate. 
CREOSOTAL.     Brand  of  Creosote  Carbonate. 

0  Creosote,    Squibb  bottle,  %  Ib.          ;  oz. 

Creosolum ;  Wood-Tar  Creosote;  Beechwood  Creosote.  Mix- 
ture of  phenols  and  phenol  derivatives,  chiefly  guaiacol  and 
creosol,  obtained  during  distillation  of  wood-tar;  preferably  of 
that  derived  from  beechwood.  This  official  Creosote  must 
not  be  confounded  with  the  cheaper  and  dangerous  so-called 
"creosote  from  coal-tar."  The  true  is  a  valuable  medicinal 
product;  the  imitation  or  coal-tar  article  is  not  only  without 
the  therapeutic  action  of  the  true  drug,  but  liable  to  produce  un- 
toward and  dangerous  results.  The  article  offered  here  has  been 
tested  with  extreme  care,  and  responds  satisfactorily  to  all 
official  requirements.  Yellowish,  oily  liquid,  of  penetrating, 
smoky  odor,  and  burning,  caustic  taste.  Sp.  gr.  not  under  1 .078. 
Slightly  soluble  in  water;  miscible  with  alcohol,  ether,  chloro-, 
form  and  oils,  and  with  up  to  3  parts  glycerin.  Antitubercular, 
Antizymotic,  Antiseptic.  Used  internally  in  phthisis,  diabetes, 
intestinal  fermentation;  externally,  in  chilblains,  burns,  etc.,  like 
carbolic  acid.  Incompatible  with  acacia,  ferric  and  cupric 
salts,  silver  salts  and  oxidizers.  Average  Dose:  4  minims  (0.25 
Cc.)  well  diluted,  or  in  tablets  or  pills.  (See  also  Tablets 
[Part  II].) 


Sirice  we  make  only  one  quality  of  each  product,  that  best 
suited  to  the  purposes  intended,  the  specification  "Squibb's" 
is  not  open  to  various  interpretations,  but  has  a  plain,  positive 
meaning.  When  ordering  or  prescribing,  specify  SQUIBB'S. 


58         SQUIBB'S  MATERIA  MEDICA 

Creosote  Carbonate,  Squibb 

bottle,  Ib.         ;  %  Ib.         ;  oz. 

Creosoti  Carbonas.  Mixture  of  carbonates  of  constituents  of 
creosote.  Colorless  to  yellowish,  thick,  oily  liquid;  faint  odor 
and  taste  of  creosote.  Sp.  gr.  1.145  to  1.170.  Insoluble  in 
water;  freely  soluble  in  alcohol,  ether,  chloroform,  fixed  oils. 
Intestinal  Antiseptic,  Antitubercular,  like  creosote.  Average 
Dose:  15  grains  (1  Gm.),  in  milk,  wine,  coffee,  etc.  Also 
used  by  inunction. 

0  Cresol,  Squibb  bottle,  Ib. 

Cresol.  Often  called  Cresylic  Acid.  Mixture  of  isomeric 
cresols,  obtained  from  coal-tar.  Yellowish  to  brownish-yellow 
liquid,  of  phenol-like  odor  and  darkening  on  exposure  to  light. 
Sp.  gr.  1 ,030  to  1 .038.  1  mil  (Cc.)  dissolves  in  about  50  mils 
water;  miscible  with  alcohol,  ether  or  glycerin.  Disinfectant 
and  Antiseptic,  like  phenol.  Average  Dose:  1  minim  (0.06 
mil).  (See  also  Solution.) 

CROCUS. 

Crocus,  N.  F.;  Spanish  Saffron.  Stigmas  of  Crocus  salivus 
(Fam.  Iridaceai).  Dark-red;  strong  aromatic  odor;  bitterish, 
aromatic  taste.  Domestic  Diaphoretic  and  Antispasmodic ;  used 
largely  as  yellow  coloring. 

Cubeb,  Powdered,  Squibb  tin,  Ib.         ;  |4  Ib. 

Cubeba;  Cubeb  Berries.  Dried,  unripe  but  fully  grown  fruits 
of  Piper  Cubeba  (Fam.  Piperacece).  Antiseptic,  Diuretic, 
Stimulating  Expectorant;  in  genito-urinary  catarrh,  respiratory 
diseases,  etc.  Average  Dose:  15  grains  (1  Gm.).  (See  also 
Fluidextract;  Oleoresin;  Troches  [Part  II].) 

Cudbear,  Squibb  Ground  for  Percolation        tin,  Ib. 

Coloring  matter  from  various  species  of  lichens.  Purplish-red 
powder.  Soluble  in  alcohol.  Used  pharmaceutically.  (See 
also  Tincture.) 

CULVER'S  ROOT.     See   Leptandra. 
Cusso.     See  Brayera. 

CYMARIN. 

Neutral  substance  from  Apocynum  cannabinum  and  A.  andro- 
scemlfollum.  Colorless,  bitter  prisms.  Readily  soluble  in  alcohol 
or  chloroform;  slightly  in  ether  or  water.  Heart  Stimulant. 
Dose :  1/200  to  1/100  grain  (0.0003  to  0.0006  Gm.)  ;  by  intra- 
venous or  intramuscular  injection  half  as  much. 

CYPRIPEDIUM. 

Cypripedium,  N.  F.;  Ladies'  Slipper.  Dried  rhizome  and 
roots  of  Cypripedium  hirsutum  or  of  C.  parviflorum  (Fam. 
Orchidaceae).  Used  as  Nerve  Stimulant  and  Tonic.  (See  also 
Fluidextract.) 


SQUIBB'S  MATERIA  MEDICA         59 

DALEY'S   CARMINATIVE.     See   Mixture  Carminative. 

DAMIANA. 

Damiana,  N.  F.  Leaves  of  Turnera  Jiffusa  or  of  T.  aphro- 
Jisiaca  (Fam.  Turneraceee).  Aromatic  odor;  aromatic,  resin- 
ous taste.  Asserted  Aphrodisiac.  Average  Dose:  30  grains 
(2  Gm.).  (See  also  Fluidextract.) 

DANDELION.     See  Taraxacum. 

DECOCTION  SARSAPARILLA  COMPOUND. 

Decoclum  Sarsaparillee  Composilum,  N.  F.  Each  100  mils 
(Cc.)  represents  10  Gm.  sarsaparilla  and  2  Gm.  each  sassafras, 
guaiac  wood,  glycyrrhiza  and  mezereum.  Antiquated  Alter- 
ative. Average  Dose:  4  fluidounces  (120  mils  [Cc.]). 

DELPHINIUM.     See  Larkspur  Seed. 

Deshler's  Salve.         See  Cerate  Rosin  Compound. 

DEWEE'S  CARMINATIVE.     See  Mixture  Magnesia  and  Asafetida. 

DEXTRIN,  WHITE. 

Dexlrinum  Album,  N.  F.  Mixture  of  soluble  carbohydrates 
and  some  unconverted  starch,  obtained  by  incomplete  hydrolysis 
of  starch  by  acids.  White,  amorphous,  odorless,  sweetish 
powder.  Completely  soluble  in  3  parts  boiling  water.  Substi- 
tute for  acacia  and  other  gums. 

f  Diacetylmorphine,  Squibb  '/8-oz-  vial, 

Diacetylmorphina.  CziHzsNQz.  White,  odorless,  bitter 
powder.  1  Gm.  dissolves  in  about  1 700  mils  (Cc.)  water, 
31  alcohol,  1.4  chloroform,  100  ether.  Similar  in  action  to 
morphine;  considered  more  toxic  than  latter,  also  habit- form- 
ing. Average  Dose:  Vao  grain  (0.003  Gm.).  Antidotes: 
potassium  permanganate  solution  by  mouth,  apomorphine  hypo- 
dermically  as  emetic;  atropine,  strychnine  or  caffeine;  hot, 
strong  coffee;  flagellation;  exercise.  (See  also  Tablets  [Part 
II].) 

f  0  Diacetylmorphine  Hydrochloride,  Squibb 

!/g-oz.  vial, 

DiacetylmorphincE  Hydrochloridum.  White,  odorless,  bitter 
powder.  1  Gm.  dissolves  in  2  mils  (Cc.)  water;  soluble  in 
alcohol;  insoluble  in  chloroform,  ether.  Action,  Dose,  etc., 
as  of  preceding.  (See  also  Tablets  [Part  II].). 

Diarrhea  Mixture.         See  Tincture  Opium  Compound. 


The  founder  of  the  House  of  Squibb,  Dr.  Edward  R.  Squibb, 
not  only  had  high  ideals,  but  lived  and  labored  for  them;  and, 
in  the  words  of  William  Miller  Bartlett,  "the  House  of  Squibb 
stands  today  as  a  living  monument  to  the  honor,  integrity,  zeal 
and  devotion  of  its  founder." 


60         SQUIBB'S  MATERIA  MEDICA 

DlASPIRIN. 

Succinyl-disalicylic  Acid.  White,  odorless,  almost  tasteless 
powder;  77  percent,  salicylic  acid.  Soluble  in  alcohol;  nearly 
insoluble  in  water  or  ether.  Diaphoretic,  Antirheumatic.  Dose : 
5  to  15  grains  (0.3  to  I  Gm.). 

Diastase  from  Malt,  Squibb       bottle,  |4  lb.        ;  oz. 

Diaslasum;  Vegetable  Diastase.  Starch-digesting  principle  de- 
veloped in  malt  or  germinated  grain.  1  part  converts  50  parts 
potato  starch  into  sugar  in  30  minutes.  Creamy-white  powder, 
tasteless,  soluble  in  water,  almost  insoluble  in  alcohol.  Starch- 
Digestant.  Average  Dose:  8  grains  (0.5  Gm.),  two  hours 
after  meals. 

Diastase  from  Pancreas,  Squibb  bottle,  oz. 

Animal  Diastase;  Amylopsin.  Starch-digesting  enzyme  of  pan- 
creas in  most  hightly  purified  form.  Active  in  neutral,  feebly 
alkaline  and  feebly  acid  solution.  1  part  transforms  125 
parts  potato  starch  into  sugar  in  30  minutes.  Starch-Digestant. 
Dose:  3  to  5  grains  (0.2  to  0.3  Gm.),  two  hours  after  meals. 

DichIoramine=T,  Squibb    bottle,  Ib.         ;  %  lb.         ;  oz. 

Toluene  -  para  -  sulphondichloramine.  CHs.CeH-t.SOoNCta. 
White  powder;  chlorous  odor.  Soluble  in  about  10  parts 
chlorcosane,  in  chlorinated  eucalyptol  or  chloroform;  insoluble 
in  water.  Introduced  by  Dr.  H.  D.  Dakin  and  colleagues  as 
powerful  Germicide  and  Disinfectant  for  use  in  oily  solution. 
Applied  to  wounds  in  2  to  5  per  cent,  solutions,  to  nose  and 
throat  in  1  per  cent,  strength,  and  to  eyes  in  0.5  to  1  per  cent, 
dilution.  Solutions  are  best  prepared  thus:  Warm  chlorco- 
sane, stir  in  Dichloramine-T  until  dissolved,  filter,  if  desired 
(usually  not  necessary),  and  cool  to  suitable  temperature  for 
use.  While  its  solutions  keep  for  quite  some  time  they  should 
be  discarded  if  they  contain  a  precipitate  that  does  not  disappear 
on  gently  warming.  (See  also  Chloramine-T  water-soluble), 
and  Halazone  Tablets  [Part  II].). 

DlETHYLMALONYLUREA.      See     Barbital. 


DlGlPOTEN. 

Mixture  of  digitalis  glucosides  in  soluble  form,  diluted  with 
milk  sugar  and  standardized  to  activity  of  digitalis  leaves. 
Dose:  same  as  latter. 

DlGIPURATUM. 

Standardized,  purified  extract  digitalis;  1  Gm.  represents  1  Gm. 
digitalis;  contains  digitoxin  and  digitalin  as  tannates.  Dose : 
same  as  of  digitalis. 


SQUIBB'S  MATERIA  MEDICA          61 

Digitalin,  Squibb  Ya-oz.vial,         ;  15-grain  vial, 

Digitalin  Germanic.  Yellowish-white  powder.  Soluble  in 
water  and  alcohol ;  almost  insoluble  in  ether  or  chloroform. 
Cardiac  Tonic  and  Diuretic,  like  digitalis.  Dose :  VlO  to 
!/2  grain  (0.006  to  0.03  Gm.),  in  pills  or  tablets.  Antidotes: 
tannic  acid,  emetics;  nitroglycerin  or  morphine  early;  strophan- 
thin  later;  camphor  and  other  stimulants.  (See  also  Tablets 
[Part  II].) 

0  Digitalis,   Squibb 

*  Whole  tin,  Ib.         ;  y4  Ib. 

Ground   for  Percolation  tin,  Ib. 

Powdered  tin,  Ib.          ;  |4  Ib. 

Digitalis;  Foxglove.  First  quality,  carefully  selected,  dried 
leaves  of  Digitalis  purpurea  (Fam.  Scrophulariacece) . 
Physiologically  assayed  according  to  U.  S.  P.;  minimum  lethal 
dose  not  more  than  0.0006  Gm.  per  Gm.  weight  of  frog. 
Also  assayed  by  the  "Cat  Method"  of  Hatcher,  for  those 
who  desire  to  administer  it  by  Eggleston  method.  Direct 
Cardiac  Stimulant,  Diuretic.  Used  in  cardiac  decompensation; 
most  efficient  when  heart  is  rapid  and  very  irregular.  Useful  in 
edema  only  when  latter  arises  from  impaired  circulation.  Nat- 
urally apt  to  cause  digestive  disturbance.  Average  Dose :  1 
grain  (0.065  Gm.).  (See  also  Extract;  Fluidextract;  Tinc- 
ture; Tablets  [Part  II].) 

DICITOL.     Brand  of  Fat-free  Tincture  Digitalis. 
Dihydroxyphthalophenone.        See  Phenolphthalein. 

DllODOHYDROXYPROPANE.      See   lothion. 

DIISOBUTYLCRESOI,    IODIDE.      See    Europhen. 

DlMAZON. 

Diacetylaminoazoioluene.  Orange-colored  powder.  Insoluble 
in  water;  readily  soluble  in  alcohol,  ether,  chloroform,  oils  and 
fats.  Cicatrizant,  Antipyic;  in  burns,  chronic  ulcers,  etc.,  in 
2  percent,  ointment  or  5  percent,  dusting  powder. 

DlMETHYLAMINOANTIPYRINE.     See   Pyramidon. 

Dimethylxanthine.         See    Theobromine. 

©  DIOMN.     A  brand  of  Ethylmorphine  Hydrochloride. 


The  Squibb  Ideals  have  taken  concrete  form  in  the  Squibb 
Products;  these  are  universally  recognized  as  standards  of 
uniform  Purity  and  Efficacy,  that  is,  general  Excellence  and 
Reliability.  Specify  SQUIBB'S  when  prescribing  or  ordering. 


62         SQUIBB'S  MATERIA  MEDICA 

DlPLOSAL. 

Salicylosalicylic  Acid;  Salicylic  Ester  of  Salicylic  Acid. 
White,  nearly  odorless,  tasteless  powder.  Soluble  in  ether, 
dilute  alkali  solutions;  almost  insoluble  in  water.  Antirheu- 
matic,  Intestinal  Antiseptic.  Dose:  8  to  15  grains  (0.5  to  1  Gm.). 

DlURETIN.     A  brand  of  Theobromine  Sodio-Salicylate. 

Dobell's  Solution.       See  Solution  Sodium  Borate,  Compound. 

Doc  GRASS.     See  Triticum. 

DOCWOOD  BARK.    See  Cornus. 

DONOVAN'S  SOLUTION.    See  Solution  Arsenic  and  Mercury  Iodide. 

Dover's  Powder.        See  Powder  Ipecac  and  Opium. 

Dover's  Powder,  Liquid.      See  Tincture  Ipecac  and  Opium. 

DROSERA. 

Drosera,  N.  F. ;  Sundew.  Air-dried  flowering  plant  of  Drosera 
rolundifolia,  D.  intermedia,  or  D.  longifolia  (Fam.  Drosera- 
ceat).  Used  in  respiratory  diseases.  Average  Dose:  60  grains 
(4  Gm.). 

DULCAMARA.     See  Bittersweet. 

DUOTAL.     A  brand  of  Guaiacol  Carbonate. 

EASTON'S  SYRUP.     See  Syrup  Iron,  Quinine  and  Strychnine  Phos- 
phates. 

ECHINACEA. 

Echinacea,  N.  F.  Dried  rhizome  and  roots  of  Brauneria  f>al- 
lida  {Echinacea  angusti folia;  Fam.  Composite).  Faint,  aro- 
matic odor;  sweetish  taste.  Used  as  Alterative.  Average 
Dose:  15  grains  (1  Gm.).  (See  also  Fluidextract.) 

Effervescent  Granular  Salts.    See      Granular      Effervescent 
Salts. 

EHRLICH'S  606.     See  Arsphenamine. 

Eisenzucker.          See  Iron  Oxide  Red,  Saccharated. 

©  ELATERIN. 

Elatennum.  From  elatenum,  a  substance  deposited  by  juice 
of  fruit  of  Ecballium  elaterium  (Fam.  Cucurbllaceee) .  White, 
odorless  crystals;  bitter,  slightly  acrid  taste.  1  Gm.  dissolves  in 
325  mils  (Cc.)  alcohol,  15.5  chloroform,  450  ether;  insoluble 
in  water.  Powerful  Hydragogue  Cathartic;  in  dropsy,  convul- 
sions, eclampsia,  etc.  Average  Dose:  I/->Q  grain  (0.003  Gm.). 
(See  also  Tablets  [Part  II].) 

ELDER   FLOWERS.     See   Sambucus. 


SQUIBB'S  MATERIA  MEDICA          63 

ELECAMPANE.    See  Inula. 

ELIXIR  ADJUVANT.     See  Elixir  Glycyrrhiza. 

ELIXIR  ALMOND  COMPOUND. 

Elixir  Amygdalae  Composition,  N.  F.  Each  100  mils  (Cc.) 
contains  0.05  mil  oil  bitter  almond,  0.1  Gm.  vanillin,  15  mils 
stronger  orange-flower  water,  with  alcohol,  syrup  and  water. 
Vehicle. 

ELIXIR  AMMONIUM  BROMIDE, 

Elixir  Ammonii  Bromidi,  N.  F.  Each  fluidounce  contains 
about  40  grains  ammonium  bromide.  Nerve  Sedative,  Anti- 
spasmodic.  Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

Elixir  Ammonium  Valerate,  Squibb  pint,  ;  gal. 
Elixir  Ammonii  Vateratis,  N.  F.  Each  fluidounce  contains  16 
grains  ammonium  valerate,  in  aromatic  elixir  with  tincture 
vanilla  and  a  little  chloroform.  Nerve  Sedative;  chiefly  in 
hysteria  and  alcoholism.  Average  Dose :  1  fluidrachm  (4  mils 
[Cc.]). 

ELIXIR  ANISE. 

Elixir  Anisi,  N.  F.;  Aniseed  Cordial.  Mixture  of  anethol,  oil 
fennel,  spirit  bitter  almond,  deodorized  alcohol,  etc.  Carmina- 
tive, chiefly  in  children.  Average  Dose  (infant) :  1 5  minims 
(1  mil  [Cc.]). 

©  Elixir  Aromatic,  Squibb  pint,         ;  gal. 

Elixir  Aromalicum;  Simple  Elixir.  Contains  1.2  volume  per- 
cent, compound  spirit  orange.  Aromatic  Vehicle,  Carminative. 

ELIXIR  AROMATIC  RED. 

Elixir  Aromalicum  Rubrum,  N.  F.  Aromatic  elixir  colored 
red  with  cudbear. 

ELIXIR  BISMUTH. 

Elixir  Bismulhi,  N.  F.  Each  fluidounce  contains  16  grains  bis- 
muth and  sodium  tartrate.  Stomachic.  Average  Dose:  1  fluid 
drachm  (4  mils  [Cc.]). 

ELIXIR    BITTER    ORANGE. 

Elixir  Aurantii  Amarl,  N.  F.  Replacing  Elixir  Curassao, 
N.  F.  III.  Each  100  rails  (Cc.)  contains  0.4  mil  oil  bitter 
orange,  2  mils  tincture  bitter  orange  peel,  2  mils  stronger 
orange-flower  water,  with  alcohol,  syrup,  and  water.  Vehicle. 


The  Squibb  Label  on  a  package  is  a  positive  guaranty  for  the 
uniform  Purity  and  Reliability  of  the  product.  We  make  only 
ONE  quality:  the  SQUIBB  quality;  and  our  prices  are  as  low 
as  they  can  be  made  for  that  quality.  Specify  SQUIBB'S. 


64         SQUIBB'S  MATERIA  MEDICA 

ELIXIR  BLACKBERRY  COMPOUND. 

Elixir  Rubi  Compositum,  N.  F.  Each  fluidounce  represents 
7J/2  grains  each  blackberry  root,  galls  and  cinnamon,  1%  grains 
cloves,  and  1  grain  each  mace  and  ginger,  together  with  syrup 
blackberry  fruit.  Antidiarrheal,  Carminative.  Average  Dose: 
4  fluidrachms  (16  mils  [Cc.]). 

ELIXIR  BLACK  HAW.     See  Elixir  Viburnum  Prunifolium. 

ELIXIR  BUCHU. 

Elixir  Buchu,  N.  F.  Each  fluidounce  represents  57  grains 
short  buchu.  Diuretic,  Urinary  Anticatarrhal.  Average  Dose: 

1  fluidrachm   (4  mils    [Cc.]).     Incompatible  with  spirit  nitrous 
ether  or  ferrous  sulphate. 

ELIXIR  BUCHU  AND  POTASSIUM  ACETATE. 

Elixir  Buchu  el  Potassii  Acetatis,  N.  F.  Each  fluidounce  rep- 
resents about  60  grains  short  buchu  and  39  grains  potassium 
acetate.  Diuretic.  Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 
Incompatible  with  spirit  nitrous  ether  or  ferrous  sulphate. 

ELIXIR  BUCHU  COMPOUND. 

Elixir  Buchu  Compositum,  N.  F.  Each  fluidounce  represents 
7^/4  grains  short  buchu,  and  14*74  grains  each  cubeb,  juniper 
and  uva  ursi.  Diuretic,  Urinary  Anticatarrhal.  Average 
Dose:  1  fluidrachm  (4  mils  [Cc.]). 

ELIXIR  CALCIUM  BROMIDE. 

Elixir  Calcii  Bromidi,  N.  F.  Each  fluidounce  contains  39 
grains  calcium  bromide.  Nerve  Sedative.  Average  Dose:  1 
fluidrachm  (4  mils  [Cc.]). 

ELIXIR  CALCIUM  HYPOPHOSPHITE. 

Elixir  Calcii  Hypophosphilis,  N.  F.  Each  fluidounce  contains 
16  grains  calcium  hypophosphite.  Used  as  Reconstructive 
Tonic.  Average  Dose:  2  fluidrachms  (8  mils  [Cc.]). 

ELIXIR  CALCIUM  LACTOPHOSPHATE. 

Elixir  Calcii  Lactophosphalis,  N.  F.  Each  fluidounce  contains 
12  grains  calcium  lactophosphate.  Used  as  Reconstructive 
Tonic,  Anticachectic;  in  scrofula,  caries,  etc.  Average  Dose: 

2  fluidrachms  (8  mils   [Cc.]). 

Elixir  Calcium  and  Sodium  Glycerophosphates,  Squibb 

pint,          ;  gal. 

Elixir  Calcii  el  SoJii  Clycerophosphaium,  N.  F.;  Each  fluid- 
ounce  contains  about  8  grains  sodium  glycerophosphate  and  4 
grains  calcium  glycerophosphate,  with  glycerin,  aromatic  elixir 
and  distilled  water.  Used  as  Nerve  Tonic.  Average 
Dose:  I  fluidrachm  (4  mils  [Cc.]). 

Elixir  Calisaya.        See  Elixir  Cinchona. 


SQUIBB'S  MATERIA  MEDICA          65 

Elixir  Calisaya  and   Hypophosphites.     See  Elixir  Cinchona 
and   Hypophosphites. 

ELIXIR  CALISAYA  AND  IRON.     See   Elixir   Cinchona   and   Iron. 

ELIXIR  CARDAMOM  COMPOUND. 

Elixir  Carclamomi  Compositum.  Each  100  mils  (Cc.)  contains 
1  mil  compound  spirit  cardamom,  with  alcohol,  syrup  and  water. 
Vehicle. 

ELIXIR  CASCARA   SAGRADA. 

Elixir  Cascarce  Sagradai,  N.  F.  Equal  volumes  aromatic  fluid- 
extract  cascara  and  aromatic  elixir.  Laxative.  Average  Dose: 
I  fluidrachm  (4  mils  [Cc.]). 

ELIXIR  CASCARA   SAGRADA  COMPOUND. 

Elixir  Cascara  Sagradas  Compositum,  N.  F.;  Laxative  Elixir. 
Each  fluidounce  represents  57  grains  cascara,  34  grains  senna 
and  30  grains  juglans,  in  aromatic  elixir.  Laxative.  Average 
Dose:  1  fluidrachm  (4  mils  [Cc.]). 

ELIXIR  CATHARTIC  COMPOUND. 

Elixir  Cathariicum  Compositum,  N.  F  Each  fluidounce  rep- 
resents 57  grains  frangula,  45J/2  grains  senna  and  28'/4  grains 
rhubarb,  with  spirit  peppermint,  solution  potassa,  and  elixir 
aromatic.  Aperient,  Cathartic.  Average  Dose :  aperient,  1 
fluidrachm  (4  mils  [Cc.]);  cathartic,  3  fluidrachms  (12  mils). 

Elixir  Cinchona  Alkaloids,  Squibb  pint,  ;  gal. 
Elixir  Cinchona  Alfyaloidorum,  N.  F. ;  Elixir  Cinchona  or 
Calisaya,  from  alkaloids.  Each  fluidounce  contains  about  I 
grain  quinine  sulphate  and  j/2  grain  each  cinchonine  and  cin- 
chonidine  sulphates.  Bitter  Tonic,  Antiperiodic.  Average 
Dose:  2  fluidrachms  (8  mils  [Cc.]). 

ELIXIR  CINCHONA  ALKALOIDS  AND  HYPOPHOSPHITES. 

Elixir  Cinchona  Allfaloidorum  el  Hypophosphitum,  N.  F. 
Each  fluidounce  contains  8  grains  each  hypophosphites  calcium 
and  sodium,  in  elixir  cinchona.  Used  as  Tonic  and  Antica- 
chectic.  Average  Dose:  2  fluidrachms  (8  mils  [Cc.]). 

ELIXIR  CINCHONA  ALKALOIDS  AND  IRON. 

Elixir  Cinchonas  Alfyaloidorum  el  Ferri,  N.  F.;  Ferrated  Elixir 
Calisaya.  Each  fluidounce  contains  16  grains  iron  phosphate, 
in  elixir  cinchona  alkaloids.  Bitter  Tonic.  Hematinic.  Average 
Dose:  2  fluidrachms  (8  mils  [Cc.]). 


This  house  supplies  only  one  quality  of  each  product:  that  best 
suited  to  the  purposes  intended.  The  specification  "Squibb's" 
is  not  open  to  various  interpretations;  it  has  a  plain,  posi- 
tive meaning.  When  prescribing,  please  specify  SOUIBB'S. 


66         SQUIBB'S  MATERIA  MEDICA 

ELIXIR  CINCOHNA  ALKALOIDS,  IRON  AND  BISMUTH. 

Elixir  Cinchonas  Alkaloidorum,  Ferri  ei  Bismulhi,  N.  F.  Each 
fluiclounce  contains  14  grains  iron  phosphate  and  8  grains  bis- 
muth and  sodium  tartrate,  in  elixir,  cinchona.  Bitter  Tonic, 
Stomachic,  Hematinic.  Average  Dose:  1  fluidrachm  (4  mils 
[Cc.]). 

ELIXIR  CINCHONA  ALKALOIDS,  IRON,  BISMUTH  AND  STRYCHNINE. 
Elixir  Cinchona  AUfaloidorum,  Fern,  Bismulhi  el  Strychnines, 
N.  F.  Each  fluidounce  contains  0.08  grain  strychnine  sulphate, 
in  elixir  cinchona,  iron  and  bismuth.  Stomachic,  Nerve  and 
Blood  Tonic.  Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

ELIXIR  CINCHONA  ALKALOIDS,  IRON  AND  PEPSIN. 

Elixir  Cinchona  AUfaloidorum,  Ferri  el  Pepsini,  N.  F.  Each 
fluidounce  contains  7J/2  grains  pepsin  and  12  grains  iron  phos- 
phate, in  elixir  cinchona.  Tonic,  Hematinic,  Digestive.  Aver« 
age  Dose:  2  fluidrachms  (8  mils  [Cc.]). 

Elixir  Cinchona  Alkaloids,  Iron  and  Strychnine,  Squibb 

pint,          ;  gal. 

Elixir  Cinchona  AUfaloidorum,  Ferri  el  Slrychninte  N.  F. 
Each  fluidounce  contains  2/25  grain  strychnine  sulphate  and  16 
grains  ferric  phosphate,  in  elixir  cinchona.  Hematinic,  Nervine. 
Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

ELIXIR  CORRIGENS.     See  Elixir  Eriodictyon  Aromatic. 

ELIXIR  CORYDALIS  COMPOUND. 

Elixir  Corydalis  Composilum,  N.  F.  Each  fluidounce  repre- 
sents 27J/2  grains  each  corydalis  and  stillingia,  13%  grains 
xanthoxylum,  41  grains  iris,  and  23  grains  potassium  iodide, 
in  aromatic  elixir.  Used  as  Antiluetic;  ace.  to  Council  on  P. 
&  C,  of  A.  M.  A.,  useless  and  therefore  harmful.  Average 
Dose:  !  fluidrachm  (4  mils  [Cc.]). 

ELIXIR  CRAMP  BARK  COMPOUND.     See  Elixir  Viburnum  Opulus 
Compound. 

Elixir  Digestive  Compound,  Squibb         pint,         ;  gal. 

Elixir  Digeslivum  Composilum,  N.  F.  Ill;  Compound  Elixir 
Pepsin.  Each  fluidounce  contains  4.6  grains  pepsin,  J/2  grain 
each  pancreatin  and  diastase,  j/j  grain  lactic  acid  and  '/? 
minim  hydrochloric  acid,  with  glycerin  and  aromatic*  elixir. 
Average  Dose:  2  fluidrachms  (8  mils  [Cc.]).  (NOTE.  Accord- 
ing to  Council  on  P.  &  C.,  of  A.  M.  A.,  "pepsin  and  pancreatin 
in  solution  are  incompatible  with  one  another.  If  the  solution 
be  neutral  or  alkaline,  the  pancreatin  gradually  destroys  the 
pepsin,  and  if  acid  the  pepsin  destroys  the  pancreatin."  We 
Coffer  this  Elixir  in  response  to  the  demands  made  on  us.) 


SQUIBB'S  MATERIA  MEDICA          67 

ELIXIR  ERIODICTYON  AROMATIC. 

Elixir  Eriodiclyi  Aromaticum,  N.  F. ;  Aromatic  Elixir  Yerba 
Santa;  Elixir  Corrigens.  Mixture  of  fluidextract  yerba  santa, 
syrup,  and  compound  elixir  taraxacum.  Each  fluidounce  rep- 
resents 27J/2  grains  eriodictyon  and  211  minims  elixir  taraxacum 
compound.  Pectoral  and  Alterative,  but  used  chiefly  as  vehicle 
for  quinine  and  other  bitter  medicaments.  Average  Dose:  1 
fluidrachm  (4  mils  [Cc.]). 

ELIXIR    FORMATES. 

Elixir  Formalum,  N.  F.  Each  fluidounce  contains  about  23 
grains  potassium  formate,  18  sodium  formate,  in  aromatic 
elixir.  Intended  as  Tonic.  Average  Dose:  2  fluidrachms  (8 
mils  [Cc.]). 

ELIXIR    FORMATES    COMPOUND. 

Elixir  Formalum  Composilum,  N.  F.  Each  fluidounce  con- 
tains about  I  1J/2  grains  sodium  formate,  10J/3  magnesium 
formate,  13%  strontium  formate,  5J/6  lithium  formate,  4  qui- 
nine formate.  Asserted  Tonic.  Average  Dose:  2  fluidrachms 
(8  mils  [Cc.]). 

Elixir  Gentian,  Squibb  pint,         ;  gal. 

Elixir  Geniiartce,  N.  F.  III.  Not  present  N.  F.  product;  of 
same  drug  strength,  but  considered  superior  because  thoroughly 
delannated.  Each  fluidounce  represents  about  16  grains  gen- 
tian, with  compound  spirit  cardamom  and  aromatic  elixir. 
Bitter  Tonic.  Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

ELIXIR  GENTIAN  FERRATED.     See  Elixir  Gentian  and  Iron  Phos- 
phate. 

Elixir  Gentian  Glycerinated,  Squibb  pint,  ;  gal. 
Elixir  Cenlianee  Glycerinalum,  N.  F.  Each  fluidounce  repre- 
sents about  4J/2  grains  gentian  and  192  minims  glycerin,  with 
sugar,  white  wine  and  small  quantities  of  fluidextract  taraxacum, 
acetic  ether,  tincture  sweet  orange  peel  and  compound  tincture 
cardamom.  Bitter  Tonic.  Average  Dose:  2  fluidrachms  (8 
mils  [Cc.]). 

Elixir  Gentian  and  Iron,  Squibb  pint;         ;  gal. 

Elixir  Centianos  el  Fern,  N.  F.;  Elixir  Gentian  with  Tinc- 
ture Iron  Chloride;  Elixir  Gentian  with  Tincture  Ferric  Citro- 
Chlonde.  Each  fluidounce  represents  about  14J/2  grains  gen- 
tian and  6  grains  iron  chloride.  Bitter  Hematinic.  Average 
Dose:  1  fluidrachm  (4  mils  [Cc.]). 


The  prices  of  the  Squibb  Products  are  in  all  instances  as  low  as 
the  quality  and  quantity  of  ingredients  and  the  expense  of  man- 
ufacture allow.  They  include  containers,  packing  and  boxing.  When 
ordering  or  prescribing  medicinal  products,  specify  SQUIBB'S. 


68         SQUIBB'S  MATERIA  MEDICA 

ELIXIR  GENTIAN  AND  IRON  PHOSPHATE. 

Elixir  Gentians  el  Ferri  Phosphatis,  N.  F.;  Elixir  Gentian 
Ferrated.  Each  fluidounce  represents  16'/2  grains  gentian  and 
8  grains  iron  phosphate.  Bitter  Tonic,  Hematopoietic.  Aver- 
age Dose:  1  fluidrachm  (4  mils  [Cc.]). 

Elixir  Glycerophosphates.     See  Elixir  Calcium  and  Sodium 
Glycerophosphates. 

Elixir  Glycerophosphates  Compound,  Squibb 

pint,          ;  gal. 

Elixir  Glycerophosphatum  Compositum,  N.  F.  Each  fluid- 
ounce  contains  about  7.3  grains  calcium  glycerophosphate,  13.5 
grains  sodium  glycerophosphate,  0.9  grain  manganese  glycero- 
phosphate, 0.45  grain  quinine  glycerophosphate  and  1 .35  grains 
iron  glycerophosphate,  with  compound  spirit  cardamom,  alcohol, 
glycerin  and  water.  Used  as  Nerve  Tonic  and  Hematinic. 
Average  Dose:  2  fluidrachms  (8  mils  [Cc.]),  before  meals. 
Keep  in  cool  place. 

ELIXIR  GLYCYRRHIZA. 

Elixir  GlycyrrbizcE ;  Elixir  Licorice.  Replacing  Elixir  Adju- 
vant U.  S.  P.  VIII  Rev.  Each  fluidounce  represents  60 
minims  fluidextract  licorice,  with  aromatic  elixir.  Vehicle  for 
bitter  and  nauseous  remedies.  Average  Dose :  2  fluidrachms  (8 
mils  [Cc.]). 

ELIXIR   GLYCYRRHIZA   AQUEOUS. 

Elixir  Glycyrrhizce  Aquosum,  N.  F.;  Aqueous  Elixir  Licorice. 
Each  fluidounce  contains  72  minims  fluidextract  licorice,  2]/2 
compound  spirit  cardamom,  96  stronger  orange-flower  water, 
with  glycerin,  syrup,  water.  Lenitive  and  Pectoral,  but  used 
chiefly  as  vehicle  for  bitter  remedies.  Average  Dose:  2  fluid 
drachms  (8  mils  [Cc.]). 

ELIXIR  LICORICE.     See  Elixir  Glycyrrhiza. 

ELIXIR  GLYCYRRHIZA  AROMATIC, 

Elixir  Glycyrrhizce  Aromaticum,  N.  F.;  Aromatic  Elixir 
Licorice.  Each  fluidounce  represents  60  minims  fluidextract 
licorice,  with  oils  of  cloves,  cinnamon,  nutmeg  and  fennel,  and 
aromatic  elixir.  Vehicle.  Average  Dose :  2  fluidrachms  (8 
mils  [Cc.]). 

ELIXIR  GUARANA. 

Elixir  Guarance,  N.  F.  Each  fluidounce  represents  about  91  J/£ 
grains  guarana,  with  aromatic  elixir  and  compound  elixir  tar- 
axacum. Sedative.  Antineuralgic;  mainly  in  nervous  headache. 
Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 


SQUIBB'S  MATERIA  MEDICA          69 

ELIXIR  HOPS. 

Elixir  Humuli,  N.  F.  Each  fluidounce  represents  57  grains 
hops,  with  tincture  vanilla,  compound  elixir  taraxacum  and 
aromatic  elixir.  Bitter  Stomachic,  Sedative.  Average  Dose:  2 
fluidrachms  (8  mils  [Cc.]). 

ELIXIR  HYPOPHOSPHITES. 

Elixir  Hypophosphitum,  N.  F.  Each  fluidounce  contains  24 
grains  calcium  hypophosphite,  and  8  grains  each  sodium  and 
potassium  hypophosphites,  with  hypophosphorous  acid,  glycerin, 
compound  spirit  cardamom  and  aromatic  elixir.  Used  as  Re- 
constructive Tonic.  Average  Dose:  2  fluidrachms  (8  mils 
[Cc.]). 

ELIXIR  HYPOPHOSPHITES  WITH  IRON. 

Elixir  Hypophosphilum  el  Ferri,  N.  F.  Each  fluidounce  con- 
tains about  4  grains  each  iron  and  potassium  hypophosphites, 
and  8,  grains  each  calcium  and  sodium  hypophosphites. 
Average  Dose:  2  fluidrachms  (8  mils  [Cc.]). 

ELIXIR  IRON  HYPOPHOSPHITE. 

Elixir  Ferri  Hypophosphilis,  N.  F.  Each  fluidounce  contains 
8  grains  iron  hypophosphite,  in  aromatic  elixir.  Hematinic. 
Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

ELIXIR  IRON  LACTATE. 

Elixir  Ferri  Lactalis,  N.  F.  Each  fluidounce  contains  8  grains 
ferrous  lactate,  in  aromatic  elixir,  with  24  grains  potassium 
citrate.  Hemaiinic.  Average  Dose :  1  fluidrachm  (4  mils  [Cc.]) 

Elixir  Iron  Phosphate,  Squibb                   pint,  ;  gal. 

Elixir  Ferri  Phosphatis,    N.    F.      Each   fluidounce  contains    16 

grains  ferric  phosphate,  in  aromatic  elixir.  Hematinic. 
Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

ELIXIR  IRON  PYROPHOSPHATE. 

Elixir  Ferri  Pyrophosphatis,  N.  F.  Each  fluidounce  contains  16 
grains  ferric  phosphate,  in  aromatic  elixir.  Hematinic. 
Average  Dose:  I  fluidrachm  (4  mils  [Cc.]). 

ELIXIR  IRON  PYROPHOSPHATE,  QUININE  AND  STRYCHNINE. 

Elixir  Ferri  Phyrophosphaiis,  Qui'mnee  el  Strychnines,  N.  F. 
Each  fluidounce  contains  about  16'/4  grains  ferric  pyrophos- 
phate,  4  quinine  sulphate,  Vltf  strychnine.  Hematinic,  General 
Tonic.  Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 


If  difficulty  is  experienced  in  procuring  any  Squibb  product, 
in  the  original  packages  here  listed,  please  notify  us;  we 
shall  see  that  your  wants  are  met  promptly  and  satisfactorily. 


70         SQUIBB'S  MATERIA  MEDICA 

Elixir  Iron,  Quinine  and  Strychnine,  Squibb 

pint,          ;  gal. 

Elixir  Fern,  Quinine  et  Strychnines,  N.  F.  Each  fluidounce 
represents  about  8  grains  ferric  chloride,  4  grains  quinine  hydro- 
chloride,  and  0.08  grain  strychnine  sulphate.  General  Tonic, 
in  debility,  convalescence,  etc.  Average  Dose:  I  fluidrachm 
(4  mils  [Cc.]). 

Elixir  Iron,  Quinine  and  Strychnine  Phosphates,  Squibb 

pint,          ;  gal. 

Essentially  Elixir  Fern,  Quinine  et  Strychnines  Phosphalum, 
U.  S.  P.  VHIth  Rev.,  but  by  a  laboratory  improvement  made 
of  a  nice  green  color  instead  of  brownish-green.  Each  fluid- 
ounce  represents  about  8  grains  iron  phosphate,  4  grains  quinine 
and  J/8  grain  strychnine.  Hematinic  and  Nervine.  Average 
Dose:  1  fluidrachm  (4  mils  [Cc.]). 

ELIXIR    LAXATIVE.         See  Elixir  Cascara  Sagrada  Compound. 

ELIXIR  LITHIUM   BROMIDE. 

Elixir  Lilhii  BromiJi,  N.  F.  Each  fluidounce  contains  about 
39  grains  lithium  bromide.  Nerve  Sedative.  Average  Dose: 
2  fluidrachms  (8  mil*  [Cc.]). 

ELIXIR  LITHIUM  CITRATE. 

Elixir  Lilhii  Citratis,  N.  F.  Each  fluidounce  contains  about  39 
grains  lithium  citrate,  in  aromatic  elixir.  Systemic  Alkali, 
Diuretic ;  chiefly  in  gout  and  rheumatism.  Average  Dose : 
2  fluidrachms  (8  mils  [Cc.]). 

ELIXIR  LITHIUM   SALICYLATE. 

Elixir  Lithii  Salicylalis,  N.  F.  Each  fluidounce  contains  about 
39  grains  lithium  salicylate,  in  aromatic  elixir.  Antirheumatic. 
Average  Dose:  2  fluidrachms  (8  mils  [Cc.]). 

Elixir  Pepsin,  Squibb  pint,         ;  gal. 

Elixir  Pepsini,  N.  F.  Each  fluidounce  contains  about  7% 
grains  pepsin,  with  hydrochloric  acid,  glycerin,  aromatic  elixir, 
etc.  Digestive.  Average  Dose:  2  fluidrachms  (8  mils  [Cc.]). 

Elixir  Pepsin  and  Bismuth,  Squibb        pint,         ;  gal. 

Elixir  Pepsini  et  Bismuthi,  N.  F.  Each  fluidounce  contains 
4  grains  pepsin  and  16  grains  bismuth  and  sodium  tartrate,  with 
glycerin,  alcohol,  syrup  and  aromatic  elixir.  Gastric  Sedative, 
Digestive.  Average  Dose:  2  fluidrachms  (8  mils  [Cc.]). 

Elixir  Pepsin,   Bismuth  and  Strychnine,  Squibb 

pint,          ;  gal. 

Elixir  Pepsin!,  Bismulh'i  el  Strychnines,  N.  F.  Each  fluidounce 
contains  4  grains  pepsin,  16  grains  bismuth  and  sodium  tartrate, 
and  0.08  grain  strychnine.  Digestive  Tonic.  Average  Dose: 
1  fluidrachm  (4  mils  [Cc.]). 


SQUIBB'S  MATERIA  MEDICA          71 

ELIXIR   PEPSIN   AND   IRON. 

Elixir  Pepsini  el  Fern,  N.  F.  Each  fluidounce  represents 
4  grains  ferric  chloride  and  8  grains  pepsin.  Digestive, 
Hematinic.  Average  Dose:  2  fluidrachms  (8  mils  [Cc.]). 

Elixir  Pepsin  and  Rennin  Compound.    See  Essence  Pepsin. 
Elixir   Pepsin    Compound.       See  Elixir  Digestive  Compound. 

ELIXIR  PHOSPHORUS. 

Elixir  Phosphori,  N.  F.  Each  fluidounce  contains  about  1/g  grain 
phosphorus.  Deteriorates  rapidly.  Bone  reconstructive  in  rickets. 
Average  Dose:  1  fluidrachm  (4  mils  [Cc.]).  Antidotes: 
potassium  permanganate;  charcoal  or  lime  water;  then 
emetics. 

ELIXIR    PHOSPHORUS    AND    Nux    VOMICA. 

Elixir  Phosphori  ei  Nucis  Vomicat,  N.  F.  Each  fluidounce 
represents  16  minims  tincture  nux  vomica  and  i/9  gram  phos- 
phorus. Deteriorates  rapidly.  Used  as  Nerve  Tonic  and 
Aphrodisiac.  Average  Dose:  I  fluidrachm  (4  mils  [Cc.]). 
Antidotes:  emetics;  potassium  permanganate;  charcoal;  lime- 
water. 

ELIXIR  POTASSIUM  ACETATE. 

Elixir  Polassii  Acetatis,  N.  F.  Each  fluidounce  contains  about 
39  grains  potassium  acetate,  with  aromatic  elixir.  Diuretic, 
Antacid;  in  dropsy,  cystitis,  rheumatic  diathesis,  etc.  Average 
Dose:  4  fluidrachms  (16  mils  [Cc.]). 

ELIXIR  POTASSIUM   ACETATE   AND  JUNIPER.    , 

Elixir  Potassii  Acetatis  el  Juniperi,  N.  F.  Each  fluidounce 
contains  about  39  grains  potassium  acetate  and  57  grains  juniper, 
in  aromatic  elixir.  Diuretic,  Urinary  Anticatarrhal.  Average 
Dose:  4  fluidrachms  (16  mils  [Cc.]). 

ELIXIR  POTASSIUM  BROMIDE. 

Elixir  Potassii  Bromidi,  N.  F.  Each  fluidounce  contains  80 
grains  potassium  bromide.  Nerve  Sedative,  Antispasmodic. 
Average  Dose:  2  fluidrachms  (8  mils  [Cc.]).  Incompatible 
with  alkaloidal  salts. 

ELIXIR  QUININE  VALERATE  AND  STRYCHNINE. 

Elixir  Quinines  Valeralis  el  Strychnines,  N.  F.  Each  fluid- 
ounce  contains  8  grains  quinine  valerale  and  0.08  grain  s'.rych- 
nine  sulphate,  in  aromatic  elixir.  Used  as  Nerve  Tonic ;  in 
hysteria,  nervousness,  etc.  Average  Dose :  1  fluidrachm  (4 
mils  [Cc.]). 


The  Squibb  products  are  recognized  everywhere  as  the  Quality 
Standard.  They  are  of  uniform  purity  and  strength,  hence 
therapeutically  dependable.  When  ordering  or  prescribing  med- 
icinal products,  you  will  do  well  always  to  specify  SQUIBB'S. 


72          SQUIBB'S  MATERIA  MEDICA 

Elixir,   Simple.          See  Elixir  Aromatic. 

Elixir  Sodium  Bromide,   Squibb  pint,         ;  gal. 

Elixir  SoJH  Bromidi,  N.  F.  Each  fluidounce  contains  80  grains 
sodium  bromide.  Nerve  Sedative,  Antispasmodic.  Average 
Dose:  2  fluidrachms  (8  mils  [Cc.]).  Incompatible  with  alka- 
loidal  salts. 

ELIXIR  SODIUM  HYPOPHOSPHITE. 

Elixir  Sodii  Hypophosphitis,  N.  F.  Each  fluidounce  contains 
16  grains  sodium  hypophosphite,  in  aromatic  elixir.  Used  as 
Tonic.  Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

ELIXIR  SODIUM  SALICYLATE. 

Elixir  Sodii  Salicylatis,  N.  F.  Each  fluidounce  contains  40 
grains  sodium  salicylate.  Antirheumatic,  Analgesic.  Average 
Dose:  1  fluidrachm  (4  mils  [Cc.]).  Incompatible  with  ferric 
salts,  solutions  quinine  salts  and  spirit  nitrous  ether. 

ELIXIR  SODIUM  SALICYLATE  COMPOUND. 

Elixir  Sodii  Salicylalis  Composilum,  N.  F.  Each  fluidounce 
contains  about  36  grains  sodium  salicylate,  1 5  minims  fluid- 
extract  condurango,  7J/2  minims  fluidextract  gelsemium,  6.8  grains 
potassium  iodide;  with  aromatic  elixir.  Antirheumatic.  Average 
Dose:  I  fluidrachm  (4  mils  [Cc.]). 

ELIXIR  STRYCHNINE*  VALERATE. 

Elixir  Srychnince  Valeratis,  N.  F.  Each  fluidounce  contains 
0.08  grain  strychnine  valerate,  with  tincture  vanilla  and  aro- 
matic elixir.  Nervine.  Average  Dose:  1  fluidrachm  (4  mils 
[Cc.]). 

Elixir  Taraxacum  Compound,  Squibb      pint,         ;  gal. 

Elixir  Taraxaci  Composilum,  N.  F.  Containing  fluidextracts 
taraxacum,  wild  cherry,  sweet  orange  peel  and  licorice,  tincture 
cinnamon,  compound  tincture  cardamom,  and  aromatic  elixir. 
Each  fluidounce  represents  16  grains  taraxacum,  9  grains  wild 
cherry  and  27J/2  grains  licorice.  Vehicle  for  bitter,  saline  or 
acrid  substances.  Average  Dose:  2  fluidrachms  (8  mils  [Cc.]). 

Elixir  Terpin  Hydrate,  Squibb  pint,         ;  gal. 

Elixir  Terpini  Hydratis,  N.  F.  Each  fluidounce  contains  8 
grains  terpm  hydrate,  with  tincture  sweet  orange  peel,  spirit 
bitter  almond,  alcohol,  glycerin,  syrup  and  water.  Stimulating 
Expectorant,  Anticatarrhal;  chiefly  in  chronic  affections  of  res- 
piratory tract.  Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 


SQUIBB'S  MATERIA  MEDICA          73 

Elixir  Terpin  Hydrate,  Squibb  pint,         ;  gal. 

Elixir  Terpini  Hydralis  et  Codeines,  N.  F.  Each  fluidounce 
contains  8  grains  terpin  hydrate  and  1  grain  codeine,  with 
tincture  sweet  orange  peel,  spirit  bitter  almond,  alcohol,  glycer- 
in, syrup  and  water.  Stimulating  Expectorant,  Cough  Seda- 
tive; chiefly  in  chronic  pectoral  affections.  Average  Dose: 
1  fluidrachm  (4  mils  [Cc.]), 

Elixir  Terpin   Hydrate  and  Diacety (morphine,  Squibb 

pint,          ;  gal. 

Elixir  Terpini  Hydralis  el  Diacetylmorphina,  N.  F.  Each 
fluidounce  contains  8  grains  terpin  hydrate  and  J/g  grain 
diacetylmorphine  hydrochloride,  with  tincture  sweet  orange  peel, 
spirit  bitter  almond,  alcohol,  glycerin,  syrup  and  water.  Stim- 
ulating Expectorant,  Cough  Sedative;  chiefly  in  chronic  pectoral 
affections.  Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

ELIXIR  THREE   BROMIDES. 

Elixir  Trium  Bromidorum,  N.  F.  Each  fluidounce  con- 
tains about  36  grains  each  ammonium,  potassium  and  sodium 
bromides,  in  compound  elixir  almond  colored  red.  Nerve 
Sedative.  Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

ELIXIR  VANILLIN   COMPOUND. 

Elixir  Vanillini  Compositum,  N.  F.  Flavoring  vehicle  con- 
taining 2  vol.  percent,  compound  spirit  vanillin,  with  little 
glycerin,  syrup  and  water. 

ELIXIR  VIBURNUM  OPULUS.  COMPOUND. 

Elixir  Virburni  Opuli  Compositum,  N.  F.;  Compound  Elixir 
Cramp  Bark.  Each  fluidounce  represents  34  grains  cramp  bark, 
68J/2  grains  beth  root  and  34'/4  grains  aletris,  with  compound 
elixir  taraxacum.  Used  as  Uterine  Tonic.  Average  'Dose : 
1  fluidrachm  (4  mils  [Cc.]). 

ELIXIR  VIBURNUM  PRUNIFOLIUM. 

Elixir  Viburni  Prunifolii,  N.  F.;  Elixir  Black  Haw.  Each 
fluidounce  represents  57  grains  viburnum  prunifolium,  with 
aromatic  elixir  and  compound  tincture  cardamom  Used  as 
Uterine  Sedative  and  Antispasmodic.  Average  Dose :  1 
fluidrachm  (4  mils  [Cc.]). 

Elixir  Vitriol.         See  Acid  Sulphuric  Aromatic. 

ELIXIR  YERBA  SANTA  AROMATIC.  See     Elixir     Eriodictyon 

Aromatic. 


Since  we  make  only  one  quality  of  each  product,  that  best 
suited  to  the  purposes  intended,  the  specification  "Squibb's" 
is  not  open  to  various  interpretations,  but  has  a  plain,  positive 
meaning.  When  ordering  or  prescribing,  specify  SQUIBB'S. 


74         SQUIBB'S  MATERIA  MEDICA 

ELIXIR   ZINC    VALERATE. 

Elixir  Zinci  Valeralis,  N.  F.  Each  fluidounce  contains  8 
grains  zinc  valerate,  with  ammonium  citrate,  spirit  bitter 
almond  and  aromatic  elixir.  Used  as  Nerve  Sedative. 
Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

ELM. 

Ulmus;  Slippery  Elm.  Bark  of  Ulmus  fuha  (Fam.  Ulma- 
cete),  deprived  of  outer  corky  layer  and  dried.  Demulc«nt. 
(See  also  Troches.) 

©  EMETINE  HYDROCHLORIDE. 

Emetina:  Hydrochloridum.  CsoJ-L^^O^HCl-f 2H2O.  Salt 
of  an  ipecac  alkaloid.  White  to  yellowish,  odorless,  bitter 
powder;  darkens  in  light.  Freely  soluble  in  water,  alcohol. 
Expectorant,  Antamebic,  Hemostatic;  in  bronchitis,  amebic 
dysentery  and  pyorrhea  alveolaris,  hemoptysis,  etc.  Average 
Dose:  Antamebic,  !/3  grain  (0.02  Gm.)  hypodermically  thrice 
daily  for  a  week,  then  discontinued  for  a  few  days  and 
resumed  if  necessary  (injected  into  gums  in  1  percent,  solu- 
tion); expectorant  Vl2  to  1/6  grain  (0.005  to  0.01  Gm.) ; 
hemostatic  J/2  to  %  grain  (0.03  to  0.04  Gm.)  subcutaneously. 

EMPYROFORM. 

Condensation  product  of  birch  tar  and  formaldehyde.  Dark 
grayish-brown,  nearly  inodorous  powder.  Soluble  in  acetone  or 
chloroform;  insoluble  in  water,  alcohol  or  ether.  Antipruritic 
and  Antiparasitic  Dermic,  in  5  percent,  ointments,  10  to  20 
percent,  pastes  or  paints. 

Emulsions. 

No  matter  how  well  made,  emulsions  will  not  keep;  hence,  we 
do  not  carry  them  in  stock,  but  we  are  prepared  to  supply 
trrem  on  special  orders  in  quantities  of  1  gallon  or  more. 

EMULSION  ALMOND. 

Emulsum  Amygdala?;  Milk  of  Almond.  6  percent,  sweet 
almonds,  with  sugar,  acacia  and  water.  Demulcent,  Vehicle. 

EMULSION  ASAFETIDA. 

Emulsum  Asafcetidce;  Milk  of  Asafcetida.  4  percent,  asafce- 
tida,  with  water.  Sedative,  Carminative;  in  hysteria,  asthma, 
convulsions,  etc.  Average  Dose:  4  fluidrachms  (16  mils). 

EMULSION  CASTOR  OIL. 

Emulsum  Olei  Ricinl,  N.  F.  35  percent,  by  volume  castor  oil, 
with  tincture  vanilla,  syrup  and  water.  Cathartic.  Average 
Dose:  \Y2  fluidounces  (48  mils  [Cc.]). 

EMULSION    COD-LJVER   OIL. 

Emulsum  Olei  Morrhua.  50  volume  percent,  of  oil,  and  hold- 
ing flavor  which  efficiently  masks  the  taste.  Alterative  Tonic, 
Nutrient.  Average  Dose:  2  fluidrachms  (8  mils  [Cc.]). 


SQUIBB'S  MATERIA  MEDICA          75 

EMULSION  COD-LIVER  OIL  WITH  CALCIUM  LACTOPHOSPHATE. 
Emulsum  Old  Morrhua  cum  Calcii  Lactophosphate,  N.  F. 
50  volume  percent,  cod  liver  oil,  with  calcium  lactophos- 
phate  (23  grains  per  fluidounce),  syrup  tolu  and  flavoring. 
Alterative,  Reconstructive,  Nutrient.  Average  Dose:  4 
fluidrachms  (16  mils  [Cc.]). 

EMULSION  COD-LJVER  OIL  WITH  CALCIUM  PHOSPHATE. 

Emulsum  Olei  Morrhucs  cum  Calcii  Laclophosphate,  N.  F.  50 
volume  percent,  cod-liver  oil,  with  calcium  phosphate  (16  grains 
per  fluidounce),  syrup  tolu  and  flavoring.  Alterative,  Nutrient, 
Reconstructive.  Average  Dose:  4  fluidrachms  (16  mils  [Cc.]). 

EMULSION  COD  LIVER  OIL  WITH   EGG. 

Emulsum  Olei  Morrhuas  cum  VHello,  N.  F.  50  vol.  percent, 
oil,  17J/2  glycerite  yolk  of  egg,  10  syrup  tolu.  Average  Dose: 
4  fluidrachms  (16  mils  [Cc.]). 

EMULSION  COD-LJVER  OIL  WITH  EXTRACT  MALT. 

Emulsum  Olei  Morrhuae  cum  Malta,  N.  F.  Each  fluidounce 
contains  144  minims  cod-liver  oil  and  260  minims  extract  malt. 
Nutritive,  Tonic.  Average  Dose:  4  fluidrachms  16  mils  [Cc.]) 

EMULSION   COD-LIVER  OIL   WITH   HYPOPHOSPHITES. 

Emulsum  Olei  Morrhuee  cum  Hypophosphitibus,  N.  F.  Each 
fluidounce  contains  240  minims  cod-liver  oil,  4.6  grains  cal- 
cium hypophosphite,  2.3  grains  each  potassium  and  sodium  hypo- 
phosphites.  Used  as  Reconstructive  Tonic,  Nutrient.  Average 
Dose:  2  fluidrachms  (8  mils  [Cc.]). 

EMULSION  COD-LIVER  OIL  WITH  WILD  CHERRY. 

Emulsum  Olei  Morrhuce  cum  Prune  Virginiana,  N.  F.  50 
volume  percent,  cod-liver  oil  and  30  grains*  wild  cherry  per 
fluidounce,  with  syrup  tolu  and  flavoring.  Alterative  Tonic, 
chiefly  in  chronic  respiratory  affections.  Average  Dose:  4 
fluidrachms  (16  mils  [Cc.]). 

EMULSION  OIL  TURPENTINE. 

Emulsum  Olei  Terebinlhince.  Each  fluidounce  contains  72 
minims  rectified  oil  turpentine  and  24  minims  expressed  oil 
almond.  Anthelmintic,  Diuretic,  Antiseptic.  Average  Dose: 
30  minims  (2  mils  [Cc.]);  as  anthelmintic,  J/2  to  1  fluidounce 
(15  to  30  mils). 

EMULSION  PETROLATUM. 

Emulsum  Petrolali,  N.  F.  Each  fluidounce  contains  about  103 
grains  petrolatum,  108  minims  expressed  oil  almond;  with  syrup, 
tincture  lemon  peel,  and  water.  Protective,  Lubricant,  Laxa- 
tive. Average  Dose:  4  fluidrachms  (16  mils  [Cc.]),  between 
meals. 

The  founder  of  the  House  of  Squibb,  Dr.  Edward  R.  Squibb, 
not  only  had  high  ideals,  but  lived  and  labored  for  them;  and, 
in  the  words  of  William  Miller  Bartlett,  "the  House  of  Squibb 
stands  today  as  a  living  monument  to  the  honor,  integrity,  zeal 
and  devotion  of  its  founder." 


76         SQUIBB'S  MATERIA  MEDICA 

©  EPINEPHRINE. 

Active  principle  of  suprarenal  gland.  Small,  white  crystals, 
sparingly  soluble  in  water  and  prone  to  oxidize,  hence  supplied 
only  in  1:1000  solution  of  its  hydrochloride  in  normal  salt 
solution  and  generally  containing  a  preservative.  Vasco-con- 
strictor,  Hemostatic;  Tonic  to  heart  muscle.  Dose:  5  to  30 
minims  (0.3  to  2  mils  [Cc.])  of  the  1:1000  solution;  hypoder- 
mically,  I  to  1 5  minims  (0.06  to  1  mil)  diluted  with  sterile 
water.  Applied  in  1:1000  to  1:10000  solution. 

Epsom    Salt,    Pure.       See    Magnesium    Sulphate. 

®  ERGOT. 

Ergola;  Spurred  Rye.  Carefuly  dried  sclerotium  of  Claviceps 
purpurea  (Fam.  Hypocreacece),  replacing  the  grain  of  rye, 
Secale  cereale  (Fam.  Grammes).  All  the  well-known  ergot 
products  offered  by  this  firm  are  made  from  yearly  importations 
of  new-crop  Spanish  ergot,  which  is  immediately  extracted  and 
made  up  into  the  various  preparations  before  deterioration  of 
the  active  principles  takes  place.  (For  full  descriptions  of  the 
various  preparations,  see  the  respective  headings  in  this  list.) 
Emmenagogue,  Hemostatic,  Circulatory  Equalizer.  Average 
Dose:  30  grains  (2  Gm.)  (See  Extract;  Fluidextract; 
Sterile  Ergot;  Tablets  [Part  II].) 

Ergot,  Sterile,  for  Hypodermic  Use.     See  Sterile  Ergot. 

ERGOTIN  BONJEAN. 

Purified   Extract  Ergot,   analogous  to  the  Squibb   extract  ergot. 

ERICIN.     See   Mesotan. 

Eriodictyon  (Yerba  Santa),  Squibb 

Ground  for  Percolation  tin,  Ib. 

Eriodictyon ;  Mountain  Balm;  Consumptive's  Weed.  Dried 
leaves  of  Eriodictyon  calif ornicum  (Fam.  Hydrophyllaceas). 
Expectorant,  but  used  chiefly  as  taste  corngent.  Average 
Dose:  15  grains  (1  Gm.).  (See  also  Fluid;  Fluidextract; 
Syrup.) 

ERYTHROXYLON.     See  Coca. 

Eserine.         See  Physostigmine. 

Essence    Peppermint.       See    Spirit    Peppermint 

Essence    Pepsin,    Squibb  bottle,  pint,        gal. 

Of  same  drug  strength  as  Elixir  Pepsini  el  Rennini  Composilum 
N.  F.,  but  differs  in  flavoring  and  vehicle  and  the  lactic  acid 
has  been  omitted  because  it  is  apt  to  interfere  with  action  of 
the  pepsin.  Each  fluidounce  contains  10'/4  grains  pepsin,  7J/2 
grains  rennin.  Digestive;  Vehicle  for  iodides  and  bromides. 
Average  Dose:  2  fluidrachms  (8  mils  [Cc.]). 


SQUIBB'S  MATERIA  MEDICA          77 

Kther,    Squibb        (specially  made  for  Anaesthesia). 

special    tins,   j/4   Ib. 

Squibb's  Ether  is  furnished  in  tin  cans  of  all  the  current  sizes 
of  the  trade,  but  the  smaller  packages,  such  as  the  J/£  Ib. 
are  especially  recommended.  One  such  can  contains  a  quantity 
sufficient  for  an  ordinary  surgical  operation;  and  in  opening  an 
original  package  for  each  operation,  the  surgeon  is  absolutely 
sure  of  a  fresh  and  otherwise  correct  supply.  It  is  a  de- 
plorable fact  that  in  some  instances  our  cans  have*  been  refilled 
with  inferior  ether.  Surgeons  will  therefore  see  that  the 
sealing  cap  is  still  intact. 

'  /Ether;  Sulphuric  Ether;  Ethylic  Ether;  Ethyl  Oxide 
(CoHs^O.  The  high-quality  Anaesthetic  Ether  here  listed  is 
made  in  the  Squibb  laboratories  by  the  original  process  de- 
vised by  Dr.  E.  R.  Squibb  in  1853,  and  by  continuous  im- 
provement long  ago  brought  to  practical  perfection,  thus  insur- 
ing a  product  of  uniform  purity,  strength  and  efficiency.  From 
the  beginning  to  the  present  day  all  Squibb  Ether  has  been 
made  only  in  the  Squibb  laboratories.  We  make  no  ether  for 
technical  uses.  This  is  in  order  to  safeguard  both  surgeon 
and  patient.  The  Squibb  Ether  is  superior  in  vital  respects 
to  U.  S.  P.  Ether,  and  by  both  laboratory  tests  and  clinical 
•experiences  extending  over  more  than  sixty  years,  it  has  been 
proved  to  be  the  purest,  best,  safest  and  most  economical 
anaesthetic  ether  made.  Squibb's  Ether  is  put  up  only  in  soldered 
tins  with  soft  metal  caps,  which  can  be  readily  cut  out  with  a 
pocket  knife  and  the  tin  then  stoppered  with  a  cork.  These 
soldered  cans  are  all  carefully  tested  for  leakage  before  they 
are  sent  out.  Sometimes,  however,  a  weak  spot  is  not  evident 
on  testing,  but  yields  to  rough  handling  during  transportation, 
and  the  can  will  leak  and  be  found  short  or  even  empty  when 
received.  In  any  such  case  we  gladly  furnish  the  purchaser 
with  a  new  package  if  he  will  send  the  defective  one  to  us. 
Soluble  in  about  10  times  its  volume  water;  miscible  in  all 
proportions  with  alcohol,  chloroform,  oils,  petroleum  benzin  and 
benzene.  Inhalation  Anaesthetic,  Anodyne,  Stimulant,  Anti- 
spasmodic;  also  Reagent.  Average  Dose  per  os:  15  minims 
(1  mil  [Cc.]).  Antidotes:  artificial  respiration;  inversion  of 
patient;  ammonia;  oxygen  or  fresh  air.  Ether  is  highly  in- 
flammable. Its  vapor,  when  mixed  with  air  and  ignited,  ex- 
plodes violently.  It  should  be  kept  in  a  cool  place,  and  remote 
from  lights  and  fire,  and  administered  only  by  daylight  or  in 
electric  light.  (See  also  Inhaler;  Spirit  Ether  Compound.) 


Ether  Anhydrous,  Reagent.        See  Reagents  (Part  IV). 


The  Squibb  Ideals  have  taken  concrete  form  hi  the  Squibb 
Products;  these  are  universally  recognized  as  standards  of 
uniform  Purity  and  Efficacy,  that  is,  general  Excellence  and 
Reliability.  Specify  SQUIBB'S  when  prescribing  or  ordering. 


78         SQUIBB'S  MATERIA  MEDICA 

Ether,   Acetic,  Squibb  bottle,  Ib. 

SElher  Acelicus,  N.  F.;  Ethyl  Acetate.  C2H5CoH3O2. 
Dropped  from  U.  S.  P.  An  exceptionally  pure  product  pre- 
pared in  special  apparatus,  from  high-grade  material.  Coloness 
liquid;  fragrant  odor;  acetous,  burning  taste.  Sp.  gr.  0.887  to 
0.895.  1  Gm.  dissolves  in  about  10  mils  (Cc.)  water;  miscible 
with  alcohol,  ether,  oils.  Stimulant,  Antispasmodic,  Anodyne; 
in  nervous  affections,  fainting,  etc.  Also  Reagent.  Average 
Dose:  15  minims  (1  mil). 

Ether,    Hydrobromic.        See  Ethyl  Bromide. 

Ether,   Sulphuric.     See   Ether. 

Ether  Inhaler.       See  Inhaler. 

Ethyl  Acetate.       See  Ether  Acetic. 

Ethyl  Bromide,  Squibb  ampul,  oz.         ;  %  oz. 

Monobromethane;  Hydrobromic  Ether.  CoHjBr.  Great  care 
is  exercised  to  insure  a  product  of  correct  specific  gravity  and 
high  purity,  factors  upon  which  the  successful  and  safe  use  of 
this  article  depends.  Colorless,  inflammable,  volatile  liquid,  of 
burning  taste  and  chloroform-like  odor.  Sp.  gr.  1 .433  to  1 .457. 
Soluble  in  alcohol,  chloroform  or  ether.  Inhalation  Anaesthetic, 
Nerve  Sedative;  used  mainly  in  minor  surgery.  Dose:  by  in- 
halation, 150  to  300  minims  (10  to  20  mils  [Cc.]);  internally, 
5  to  10  drops,  on  sugar  or  in  capsules.  On  exposure  to  light  it 
is  likely  to  become  discolored  from  liberation  of  bromine.  Keep 
from  light,  air  and  fire.  Must  not  be  confounded  with  poison- 
ous Ethylene  Bromide.  (See  also  Inhaler.) 

ETHYL  CARBAMATE. 

SEthylis  Carbamas;  Urethane;  Ethyl  Urethane.  CsHrNOo. 
Ethyl  ester  of  carbamic  acid.  Colorless,  odorless  crystals;  cool- 
ing saline  taste.  1  Gm.  dissolves  in  0.45  mil  (Cc.)  water,  0.8 
alcohol,  2.5  glycerin,  0.9  chloroform,  1 .5  ether,  32  olive  oil. 
Mild  and  relatively  harmless  Hypnotic.  Average  Dose:  15 
grains  (1  Gm.).  Incompatible  in  triturations  with  antipyrine, 
butylchloral  hydrate,  camphor,  carbolic  acid,  menthol,  naphthol, 
resorcin,  salol  or  thymol;  with  acids  or  alkalies. 

©  Ethyl  Chloride,  Squibb 

30  Cc.  glass  tubes  with  fine  capillary  delivery  tube  having  auto- 
matic closing  cap,  for  local  anaesthesia,  each 
50  Cc.  glass  graduated  tubes,  with  coarse  capillary  delivery  tube 
having  automatic  closing  cap,  for  general  anaesthesia,  each 
60  Cc.  glass  tubes  with  fine  capillary  delivery  tube  having  auto- 
matic closing  cap,  for  local  anaesthesia,  each 
/£//7p/is  Chloridum;  Monochlorethane.  CoH-,Cl.  Squibb's 
Ethyl  Chloride  is  a  true,  pure  Ethyl  Chloride,  eminently  suited 
for  General  as  well  as  Local  Anaesthesia.  Prepared  and  puri- 
fied in  the  Squibb  Laboratories.  Colorless,  volatile,  inflammable 
liquid,  of  agreeable  odor  and  burning  taste.  Sp.  gr.  about  0.921 
at  0°C.;  boiling-point  12°  to  13°C.  Soluble  readily  in  al- 
cohol or  ether;  slightly  in  water.  Dose  (by  inhalation  as  gen- 
eral anaesthetic):  1  to  3  fluidrachms  (4  to  12  mils  [Cc.]).  Keep 
from  light  and  fire.  Inflammable! 


SQUIBB'S  MATERIA  MEDICA          79 

Ethyl  Chloride  Inhaler.        See  Inhaler. 

f®ETHYLMORPHINE    HYDROCHLOR1DE. 

/EihylmoTphin&  Hydrochloridum;  Dionin.  CigH^OsNHCl 
2H2O.  From  morphine  by  ethylation.  White  or  yellowish- 
white,  odorless,  bitter  powder.  1  Gm.  dissolves  in  8  mils  (Cc.) 
water,  22  alcohol;  slightly  soluble  in  ether,  chloroform.  Ocu- 
lar Lymphagogue;  Analgesic,  intermediate  between  morphine 
and  codeine.  Average  Dose:  |4  grain  (0.015  Gm.) 

Ethyl   Oxide.  See  Ether. 

EUCAINE.     See  Betaeucaine  Hydrochloride. 

©  Eucalyptol,    Squibb  bottle,  Ib.         |4  lb.          ;  oz. 

Eucalyptol;  Cineol;  Cajuputol.  CioHigO.  From  volatile  oil 
eucalyptus  and  other  sources.  Colorless  liquid,  of  aromatic, 
camphoraceous  odor,  and  pungent,  spicy,  cooling  taste.  Sp.  gr. 
0.921  to  0.923.  Miscible  with  alcohol,  ether,  chloroform  and 
fatty  oils;  almost  insoluble  in  water.  Local  Stimulant,  Anti- 
septic, Deodorant;  by  inhalation,  in  diphtheria,  asthma,  etc. 
Average  Dose:  5  minims  (0.3  mil  [Cc.]),  in  emulsion  or  cap- 
sules or  on  sugar. 

©  EUCALYPTUS. 

Eucalyptus;  Blue  Gum  Tree.  Dried  leaves  of  Eucalyplus 
Clobulus  (Fam.  M^rtaces).  Antiperiodic,  Tonic.  Average 
Dose:  30  grains  (2  Gm.).  (See  also  Fluidextract.) 

Eugenol,  Squibb  bottle,  oz. 

Eugenol;  Eugenic  or  Caryophyllic  Acid.  CioHjoOo.  An  un- 
saturated  aromatic  phenol  obtained  from  clove  oil,  and  other 
sources.  Colorless  or  pale-yellow  liquid,  of  strong  clove  odor, 
and  pungent,  spicy  taste,  and  becoming  darker  and  thicker  on 
exposure.  Sp.  gr.  1.064  to  1.070.  Miscible  with  alcohol, 
chloroform,  ether  or  fixed  oils.  Antiseptic,  Antitubercular, 
Local  Anaesthetic  (in  dentistry).  Average  Dose:  3  minims 
(0.2  mil  [Cc.]). 

EUMYDRIN. 

Methylatropine  Nitrate.  White,  odorless,  permanent  crystals. 
Soluble  in  water  or  alcohol,  sparingly  in  ether  or  chloroform. 
Mydriatic,  Antihydrotic,  Antispasmodic.  Applied  in  */2  to  1 
percent  solution.  Dose:  Veo  to  Vso  grain  (0.001  to  0.002  Gm.). 

EUONYMUS. 

Euonymus,  N.  F.;  Wahoo;  Spindle  Tree.  Dried  bark  of  root 
of  Euonymus  atropurpureus  (Fam.  Celastracece).  Laxative;* 
uncertain  as  to  absorption.  Average  Dose:  8  grains  (0.5  Gm.). 


The  Squibb  Label  on  a  package  is  a  positive  guaranty  for  the 
uniform  Purity  and  Reliability  of  the  product.  We  make  only 
ONE  quality:  the  SQUIBB  quality;  and  our  prices  are  as  low 
as  they  can  be  made  for  that  quality.  Specify  SQUIBB'S. 


80         SQUIBB'S  MATERIA  MEDICA 

EUPATORIUM. 

Eupatorium,  N.  F.;  Boneset;  Thoroughwort.  Dried  leaves  and 
flowering  tops  of  Eupatorium  perfoliatum  (Fam.  Composite), 
Domestic  Diaphoretic  tea.  Average  Dose:  30  grains  (2  Gm.). 

EUPHORBIA  PILULIFERA. 

Euphorbia  Pilulifera,  N.  F.;  Pill-bearing  Spurge.  Dried  herb 
of  Euphorbia  pilulifera  (Fam.  Euphorbiacea) ,  collected  while 
flowering  and  fruiting.  Aromatic  odor;  faintly  bitter,  aromatic, 
acrid  taste.  Used  mainly  in  asthma  and  chronic  bronchitis. 
Average  Dose:  30  grains  (2  Gm.). 

EUPHTHALMIN. 

Ci7H25NOs.HCl.  Mandelic  acid  derivative  of  eucaine. 
White  powder.  Soluble  readily  in  water  or  alcohol.  Mydri- 
atic,  in  5  to  10  percent,  solutions. 

EUQUININE. 

Quinine  Ethylcarbonate.  Coar^s^O^  White,  light,  fleecy, 
acicular  conglomerations,  practically  tasteless.  Soluble  readily 
in  acohol,  ether,  chloroform;  sparingly  in  water.  Solutions  are 
bitter.  Succedaneum  for  quinine  sulphate.  Dose :  2  to  1 5 
grains  (0.13  to  1  Gm.). 

EUROPHEN. 

Diisobutylcresol  Iodide.  C22H29OoI.  Bulky,  yellow  powder, 
of  saffron  odor;  28  percent,  iodine.  Soluble  in  alcohol,  ether, 
chloroform,  fixed  oils;  insoluble  in  water.  Wound  Antiseptic, 
Antisyphilitic.  Dose:  2  to  5  grains  (0.13  to  0.3  Gm.). 

EXTRACTS,  SQUIBB 

The  careful  selection  of  prime  drugs  and  the  accurate  prelim- 
inary assays  to  which  they  are  subjected,  combined  with  their 
complete  exhaustion  by  the  Squibb  method,  insure  thoroughly 
reliable  preparations.  The  solid  extracts  are  made  by  evapora- 
tion at  low  temperatures,  thus  preventing  the  loss  of  the  volatile 
constituents,  chemical  changes  and  the  rendering  insoluble  of 
the  active  principles.  These  extracts  will  be  found  to  be  ex- 
ceptionally active,  soluble  and  uniform  in  dosage.  Those  which 
are  official  in  the  pharmacopoeia  are  made  to  conform  accur- 
ately and  absolutely  with  U.  S.  P.  standards.  A  number  of 
*  extracts  not  official  are  assayed  and  adjusted  to  a  required 
strength.  These  instances  are  noted  under  the  individual  ex- 
tracts in  the  following  list.  All  the  solid  extracts  are  put  up 
in  containers  of  the  proper  capacity,  with  sufficient  room  for 
ihe  contents  to  expand  under  the  ordinary  changes  of  a  tem- 
perate climate.  They  should  not  be  sub'ccted  tr>  -»n  unusual 
heat,  however. 


SQUIBB'S  MATERIA  MEDICA          81 

0  Extract  Aconite  Powdered*,  Squibb          bottle,  oz. 

Exlraclum  Aconiti.'  Newly  official.  1  Gjn.  represents  about 
4  Gm.  drug.  Required  by  U.  S.  P.  to  assay  1.8  to  2.2  percent, 
ether-soluble  alkaloids.  Physiologically  assayed  by  U.  S.  P. 
method;  minimum  lethal  dose  not  greater  than  0.00001  Gm. 
per  Gm.  weight  of  guinea-pig.  Circulatory  Sedative,  Sudorific, 
Antineuralgic.  Average  Dose:  J/c  grain  (0.01  Gm.).  Anti- 
dotes: emetics;  atropine,  digitalis  or  ammonia;  small,  frequent 
doses  of  stimulants;  artificial  respiration. 

Extract  Aconite  Root  Soft,  Squibb 

glass  jar,  ]/4  Ib.          ;  oz. 

From  dried  tuberous  root  of  Aconltum  Napellus.  Assays  1.8 
to  2.2  percent,  alkaloids.  Dose :  J/g  to  %  grain  (0.008  to  0.15 
Gm.). 

0  Extract  Aloes  (Powdered),  Squibb 

bottle,  J4  Ib.          ;  oz. 

Exlraclum  Aloes,  N.  F.  Aqueous.  1  Gm.  represents  2  Gm. 
drug.  Cathartic;  acts  mostly  on  large  intestine.  Average  Dose: 
2  grains  (0.13  Gm.). 

EXTRACT  APPLES  FERRATED. 

Exlraclum  Fern  Pomalum,  N.  F.;  Crude  Iron  Malate.  From 
fresh  juice  of  sour  apples  and  reduced  iron.  Contains  about 
10  percent.  Fe.  Mild  Hematinic.  Average  Dose:  10  grains 
(0.65  Gm.). 

EXTRACT  BEEF. 

Exlraclum  Carnis,  N.  F.  Residue  left  on  evaporating  fresh  beef 
broth  at  low  temperature.  Yellowish-brown  to  dark-brown, 
pasty  mass;  meat-like  odor  and  taste.  Nutrient. 

Extract  Belladonna  Leaves  Powdered,  Squibb 

bottle,   oz. 

Exlraclum  Belladonna  Foliorum.  Assays  1.18  to  132  percent, 
alkaloids.  Anodyne,  Antispasmodic,  Antihydrotic.  Average 
Dose:  j/4  grain  (0.015  Gm.).  Antidotes:  emetics;  morphine, 
pilocarpine,  physostigmine  or  aconitine. 

0  Extract  Belladonna  Leaves  Soft*,  Squibb 

glass  jar,  '/^  Ib.          ;  oz. 

Exlraclum  Belladonna  Foliorum.  From  dried  leaves  and  tops 
of  Alropa  Belladonna.  1  Gm.  represents  about  4  Gm.  drug. 
Assays  1.18  to  1.32  percent,  alkaloids.  Anodyne,  Antispas- 
modic, Antihydrotic.  Average  Dose:  %  grain  (0.015  Gm.). 
Antidotes:  emetics;  morphine,  pilocarpine,  physostigmine  or 
aconitine. 


This  house  supplies  only  one  quality  of  each  product:  that  best 
suited  to  the  purposes  intended.  The  specification  "Squibb's" 
is  not  open  to  various  interpretations;  it  has  a  plain,  posi- 
tive meaning.  Therefore,  when  prescribing,  specify  SQUIBB'S. 


82          SQUIBB'S  MATERIA  MEDICA 

EXTRACT  BLACK  COHOSH.     See  Extract  Cimicifuga. 
EXTRACT  BLACK  HAW.     See  Extract  Viburnum  Prunifolium. 
EXTRACT  CALABAR  BEAN.     See  Extract  Physostigma. 

Extract   Cannabis   Powdered,   Squibb  1-oz.  vial 

1  Gm.  represents  4  Gm.  drug.  Dose:  1/3  to  1  grain  (0.02  to 
0.065  Gm.). 

Extract  Cannabis  Soft*,  Squibb  glass  jar,  oz. 

Exlraclum  Cannabis.  From  dried  flowering  tops  of  pistillate 
planjs  of  Cannabis  Saliva  or  C.  indica.  1  Gm.  represents 
about  8  Gm.  drug.  Physiologically  assayed  according  to  U.  S. 
P.  Incoordination  produced  by  0.004  Gm.  per  Kgm.  weight 
of  dog.  Narcotic,  Sedative,  Anodyne.  Average  Dose:  J/6 
grain  (0.01  Gm.).  Antidotes:  emetics;  atropine,  strychnine  or 
caffeine,  hypodermically;  strong  coffee. 

0  Extract  Cascara  Sagrada  (Powdered),  Squibb 

bottle,  |4  lb.  ;  oz. 

Exlractum  Cascars  Sagradce  (Rhamni  Purshiante).  1  Gm. 
represents  3  Gm.  thoroughly  seasoned  Cascara  bark.  Laxa- 
tive, acting  mainly  on  colon;  has  little  tendency  to  produce 
secondary  constipation.'  Average  Dose:  4  grains  (0.25  Gm.). 
(See  also  Tablets  [Part  II].) 

EXTRACT  CIMICIFUGA  (POWDERED). 

Exlraclum  Cimifuga ;  Extract  Black  Cohosh.  From  dried 
rhizome  and  roots  of  Cimicifuga  racemosa.  1  Gm.  represents 
about  4  Gm.  drug.  Used  as  Alterative,  Stomachic  and  Anti- 
spasmodic.  Average  Dose:  4  grains  (0.25  Gm.). 

EXTRACT  CINCHONA  (SOFT). 

Exlraclum  Cinchona,  N.  F.  Yields  22  to  26  percent,  alkaloids. 
Average  Dose:  4  grains  (0.25  Gm.). 

EXTRACT    COLCHICUM    CORM    (POWDERED). 

Exlraclum  Colchici  Cormi.  Not  the  soft,  acetic  extract  of 
U.  S.  P.  Vlllth  Rev.  1  Gm.  represents  about  4  Gm.  drug. 
Assays  1 .25  to  1 .55  percent,  colchicine.  Average  Dose  :  1  grain 
(0.065  Cm.). 

0  Extract  Colocynth  (Powdered),  Squibb     1-oz.  vial 
Exlractum  Colocynlhidis.     From  pulp  of  dried  fruit  of  Cilrullus 
Colocyrilhis ;    not    from   entire    fruit.      1    Gm.   represents  4   Gm. 
drug.    Drastic  Cathartic.    Average  Dose:  ]/2  grain  (0.03  Gm.). 

0  Extract  Colocynth  Compound  (Powdered)    Squibb 

bottle,  ;    !4    lb.  ;    oz. 

Exlraclum  Colocynlhidis  Composilum.  From  extract  colocynth, 
aloes,  cardamom,  resin  scammony  and  soap.  Becomes  impacted 
or  caked  on  keeping,  more  rapidly  when  subjected  to  undue  heat 
or  moisture.  When  in  this  condition  pressure  of  a  spatula 
usually  restores  original  powdered  state,  Drastic  Cathartic. 
Average  Dose:  4  grains  (025)  Gm.). 


SQUIBB'S  MATERIA  MEDICA         83 

EXTRACT  CONIUM   (SOFT). 

Extractum  Conn,  N.  F.  Assays  1 .8  to  2.2  percent,  conine.  Anti- 
spasmodic,  Sedative,  Anodyne.  Average  Dose:  ]/2  grain  (0-03 
Gm.).  Antidotes:  tannin,  emetics;  atropine,  strychnine,  caffeine. 

Extract  Culver's  Root.      See   Extract   Leptandra. 
Extract  Dandelion.         See  Extract  Taraxacum. 

Extract  Digitalis  Powdered,  Squibb  1-oz.  vial 

1  Gm.  represents  4  Gm.  drug.  Dose:  VlO  to  '/5  grain  (0.006 
lo  0.012  Gm.). 

®  Extract  Digitalis  Soft,  Squibb 

glass  jar,  ;  •  j/4  lb.  ',   oz. 

Exlractum  Digitalis,  U.  S.  P.  Vlllth  Rev.;  Extract  Foxglove. 
Prepared  from  fluidextract.  1  Gm.  represents  2J/2  Gm.  digitalis, 
the  dried  leaves  of  Digitalis  purpurea.  Heart  Tonic,  Diuretic. 
Average  Dose:  !/6  grain  (0.01  Gm.).  Antidotes:  tannin, 
emetics;  strychnine  or  alcohol;  morphine;  rest  in  horizontal 
position. 

Extract  Ergot  Soft,  Squibb  glass  jar,  %  Ib.  ;  oz. 
in  aseptic  capsules  holding  60  grs.,  5  in  a  vial,  per  vial. 
Introduced  over  30  years  ago  by  Dr.  E.  R.  Squibb,  and  since 
then  the  standard  extract  ergot  of  the  world.  Prior  to  U.  S.  P. 
Vlllth  Rev.  it  was  the  official  article,  but  for  no  satisfactorily 
explained  reason  the  formula  was  changed  in  that  revision  and 
again  in  present  edition.  Almost  entirely  soluble  in  cold 
water.  1  Gm.  represents  5  Gm.  best  Spanish  ergot.  Physi- 
ologically tested  and  proved  of  full  activity,  hence  dependable. 
5  Gm.  dissolved  in  20  mils  (Cc.)  water,  filtered  and  made  up  to 
25  mils  by  passing  water  through  the  filter,  makes  a  solution 
of  strength  of  official  fluidextract  and  for  many  uses  superior 
to  latter,  because  free  from  alcohol  and  other  irritating  sub- 
stances. This  solution  is  well  adapted  for  hypodermic  use  and 
should  be  made  up  only  as  needed.  Emmenagogue,  Oxytocic, 
Hemostatic,  Circulatory  Equalizer.  Average  Dose :  4  grains 
(0.25  Gm.).  (See  also  Sterile  Ergot,  for  hypodermic  use; 
Tablets.) 

Extract   Ergot   Powdered,  Squibb  bottle,  oz., 

1     Gm.    represents    4    Gm.   best    Spanish    ergot.    Physiologically 
tested.      Average    Dose:   5   grains    (0.3    Gm.). 


The  prices  of  the  Squibb  Products  are  in  al!  instances  as  low  as 
the  quality  and  quantity  of  ingredients  and  the  expense  of  man- 
ufacture allow.  They  include  containers,  packing  and  boxing.  When 
ordering  or  prescribing  medicinal  products,  specify  SQUIBB'S. 


84         SQUIBB'S  MATERIA  MEDICA 

EXTRACT  EUONYMUS   (POWDERED). 

Exlractum  Euonymi,  N.  F.;  Extract  Wahoo.  Prepared  from 
fluidextract.  1  Gm.  represents  4  Cm.  euonymus,  the  dried  bark 
of  root  of  Euonymus  atropurpureus.  Cathartic  of  uncertain 
absorption;  hence  inadvisable.  Average  Dose:  2  grains  (0.13 
Gm.). 

EXTRACT  GELSEMIUM  (POWDERED). 

Exiraclum  Gelsemii.  Newly  official.  1  Gm.  represents  4  Gm. 
Gelsemium,  the  dried  rhizome  and  roots  of  Celsemium  sem- 
pervirens.  Antineuralgic,  Nerve  Sedative,  Antispasmodic;  in 
neuralgia,  dysuria,  hysteria,  dysmenorrhea,  delirium  tremens,  etc. 
Average  Dose:  i/6  grain  (0.01  Gm.).  Antidotes:  tannin, 
emetics;  atropine  or  strophanthin  subcutaneously ;  stimulants. 

Extract   Gentian   Powdered,  Squibb 

bottle,         ;  14  lb.          ;  oz. 

1  Gm.  represents  2  Gm.  drug.  Dose :  3  to  6  grains  (0.2  to  0.4 
Gm.). 

0  Extract  Gentian  Soft*,  Squibb 

glass  jar,          ^  14  lb.         ;  oz. 

Exiraclum  Genliana.  Aqueous.  1  Gm.  represents  2]/2  Gm. 
gentian,  the  dried  rhizome  and  root  of  Genliana  lutca.  Bitter 
Tonic;  Stomachic;  Pill  Excipient.  Average  Dose:  4  grains 
(0.25  Gm.). 

Extract   Glycyrrhiza  Powdered,  Squibb 

bottle,          ;    14   lb.          ;    oz. 

Extract  Licorice  Powdered.  1  Gm.  represents  2  Gm.  drug. 
Lenitive,  Demulcent.  Ordinary  Dose:  15  grains  (1  Gm.). 
Used  chiefly  to  cover  taste  of  bitter  drugs. 

Extract  Glycyrrhiza  Pure*,  Squibb 

glass  jar,  14  lb.          ;  oz. 

Exlractum  Glycyrrhiza  Purum;  Pure  Extract  Licorice.  Pilu- 
lar.  1  Gm.  represents  2.75  Gm.  select  licorice  root.  Demul- 
cent, Pectoral,  Lenitive,  sweetening  agent,  pill  excipient.  Or- 
dinary Dose:  15  grains  (1  Gm.).  Keep  cool;  liable  to  get 
mouldy  in  warm  place. 

EXTRACT  GOLDEN  SEAL.     See  Extract  Hydrastis. 
Extract,  Goulard's.         See  Solution  Lead  Subacetate. 

EXTRACT  HEMATOXYLON  (POWDERED). 

Exiraclum  Hsmatoxyll,  N.  F.;  Extract  Logwood.  Aqueous.  1 
Gm.  represents  16  Gm.  hematoxylon,  the  heart-wood  of  Hcema- 
toxylon  campechianum.  Intestinal  Astringent.  Average  Dose : 
15  grains  (1  Gm.). 

Extract   Henbane.      See  Extract  Hyoscyamus. 


SQUIBB'S  MATERIA  MEDICA         85 

EXTRACT  HYDRASTIS  (POWDERED). 

Exiractum  Hydraslis ;  Extract  Golden  Seal.  Newly  official. 
1  Gm.  represents  about  4  Gm.  Hydrastis,  the  dried  rhizome 
and  roots  of  Hydrastis  canadensis;  assays  9  to  1 1  percent, 
ether-soluble  alkaloids.  Hemostatic,  Alterative,  Bitter  Tonic; 
in  uterine  hemorrhage,  catarrhal  jaundice,  etc.  Average 
Dose:  8  grains  (0.5  Gm.). 

Extract   Hyoscyamus  Powdered,  Squibb       1-oz.  vial 

Assays  about  0.3  percent,  alkaloids.  Dose:  J/2  to  1J/2  grains 
(0.03  to  0.1  Gm.). 

Extract  Hyoscyamus  Soft*,  Squibb  glass  jar  oz. 

Extraclum  Hyoscyami;  Extract  Henbane.  I  Gm.  represents 
about  4  Gm.  hyoscyamus,  the  dried  leaves  and  flowering  or 
fruiting  tops  of  Hyoscyamus  niger.  Assays '0.22  to  0.28  per- 
cent, alkaloids.  Antispasmodic,  Sedative,  Analgesic;  in  coughs, 
hysteria,  emphysema,  nervous  headache,  etc.  Average  Dose :  1 
grain  (0.065  Gm,).  Antidotes:  tannin,  emetics;  morphine, 
pilocarpine,  physostigmine,  aconitine. 

EXTRACT  IGNATIA  (POWDERED). 

Extracium  Ignalia;,  N.  F.  Yields  5.4  to  6.6  percent,  alkaloids. 
Nerve  Stimulant,  Gastro-intestinal  Tonic.  Average  Dose: 
J/2  grain  (0.03  Gm.).  Antidotes:  tannin  then  apomorphine 
hypodermically;  chloral  with  bromides  per  rectum; chloroform 
inhalation  if  necessary. 

Extract  Jalap  Powdered,  Squibb 

bottle,          ;    %   Ib.  ;    oz. 

From  dried   tuberous   root  of  Exogonium  Purga.  Adjusted   to 

strength  of  60  percent,   total   resin  by  milk  sugar,  which   serves 

to  keep   it   in   powder   as  long  as   undue  heat   and  moisture   are 

avoided.  Hydragogue  Cathartic.  Dose:  2  to  5  grains  (0.13 
to  0.3  Gm.). 

Extract   Jalap     Soft*,  Squibb  glass  jar,  oz. 

Extraclum  Jalaps,  N.  F.     Average  Dose:  15  grains  (1   Gm.). 

EXTRACT  KRAMERIA  (POWDERED).. 

Extractum  Krameria,  N.  F.;  Extract  Rhatany.  Aqueous.  1 
Gm.  represents  4  Gm.  krameria.  Powerful  Astringent;  ex- 
ternally in  leucorrhea,  spongy  gums,  etc.,  in  2  to  10  percent, 
solutions;  internally  in  diarrhea.  Average  Dose :  8  grains 
(0.5  Gm.). 


Jf  difficulty  is  experienced  in  procuring  any  Squibb  product, 
in  the  original  packages  here  listed,  please  notify  us;  we 
shall  see  that  your  wants  are  met  promptly  and  satisfactorily. 


86         SQUIBB'S  MATERIA  MEDICA 

Extract  Leptandra  (Powdered),  Squibb         bottle,  oz. 
Extractum  Leptandrs,  N.  F.;    Extract  Culver's  Root.      1    Gm. 
represents   4   Gm.    leptandra,    the    dried   rhizome   and    roots   of 
Veronica     virginica.     Cathartic,     acting     somewhat     like     resin 
podophyllum.     Average  Dose:  4  grains  (0.25  Gm.). 

Extract  Male  Fern.     See  Oleoresin  Aspidium. 

Extract  Malt,  Squibb  pint,         ;  gal. 

Extractum  Malti.  Syrupy.  1  Gm.  represents  1.5  Gm.  drug. 
Tonic,  Digestive,  emulsifying  agent.  Average  Dose :  4  drachms 
(15  Gm.). 

EXTRACT  MUSK  ROOT.     See  Extract  Sumbul. 

®  Extract   Nux   Vomica    (Powdered),    Squibb 

bottle,          ;  !4  lb.          5   oz. 

Extraclum  Nucis  Vomicai.  Assays  15.2  to  16.8  percent,  alka- 
loids (equivalent  to  about  8  percent,  strychnine).  One  and 
three-fifths  times  as  strong  as  former  official  product.  Bitter 
Stomachic  and  Tonic.  Average  Dose:  J/4  grain  (0.015  Gm.). 
Antidotes:  tannin;  apomorphine  subcutaneously  as  emetic; 
chloral  hydrate  and  bromides  per  rectum;  chloroform  by 
inhalation  if  necessary. 

f©  Extract   Opium   (Powdered),  Squibb 

bottle,  oz.          ;  J/2  oz. 

Extractum  Opii.  Aqueous.  Assays  19.5  to  20.5  percent. 
.  anhydrous  morphine.  Antispasmodic,  Anodyne,  Cerebrospinal 
Depressant.  Average  Dose:  Y2  grain  (0.03  Gm.).  Antidotes: 
potassium  permanganate  (2  grains  in  water),  then  emetics;  hot 
strong  coffee;  atropine  or  strychnine;  exercise. 

®  Extract  Oxgall   (Powdered),  Squibb  1-oz.  vial 

Extractum  Fellis  Bovis.  Newly  official.  1  Gm.  represents 
8  Gm.  oxgall.  Laxative,  Cholagogue,  Intestinal  Digestive;  in 
typhoid  fever,  intestinal  indigestion,  deficient  biliary  secretion, 
etc.  Average  Dose:  lj/2  grains  (0.1  Gm.).  (See  also  Oxgall 
Purified;  Tablets.) 

EXTRACT  PHYSOSTIGMA  (POWDERED). 

Exlractum  Physostigmaiis ;  Extract  Calabar  Bean.  Assays 
1.7  to  2.3  percent,  alkaloids.  Antitetanic,  Antineuralgic, 
Peristaltic.  Average  Dose:  J/g  grain  (0.008  Gm.).  Antidotes: 
emetics;  atropine  or  strychnine  hypodermically ;  pilocarpme; 
chloral  hydrate;  stimulants. 

EXTRACT  PODOPHYLLUM  (SOFT). 

Extractum  Podophylll,  N.  F.  Slow  but  effective  and  rather 
irritant  Cathartic.  Average  Dose :  %  grain  (0.015  Gm.). 


SQUIBB'S  MATERIA  MEDICA          87 

EXTRACT  QUASSIA  (POWDERED). 

Exlracium  Quassia,  N.  F.  Aqueous.  1  Gin.  represents  10 
Gm.  drug.  Bitter  Stomachic.  Average  Dose:  1  grain 
(0.065  Gm.). 

EXTRACT  RHATANY.     See  Extract  Krameria. 

©  Extract  Rhubarb   (Powdered),  Squibb     bottle,  oz. 
Extraclum  Rhel.     The  new  U.  S.  P.  recognizes  the  pondered 
extract,  as  against  soft  in  preceding  edition.      I    Gm.  represents 
2  Gm.  drug.     Laxative.     Average  Dose:  4  grains  (0.25  Gm.). 

Extract    Stramonium    Powdered,    Squibb    bottle,  oz. 

Exlractum  Stramonii.  Assays  0.9  to  1.1  percent,  alkaloids, 
Average  Dose:  !/G  gram  (0-0'  Gm.). 

Extract  Stramonium  Soft*,  Squibb 

glass  jar,          ',    ]/4   lb.          ;    oz. 

Exlractum  Stramonii.  From  dried  leaves  of  Datura  Stramonium 
or  of  D.  Tatula.  \  Gm.  represents  about  4  Gm.  drug.  Assays 
0.9  to  1.1  percent,  alkaloids.  Antispasmodic,  Sedative,  Analgesic. 
Average  Dose:  !/£  grain  (0.01  Gm.).  Antidotes:  tannin;  apo- 
morphine  hypodermically  as  emetic;  morphine;  ammonia  by  in- 
halation. 

EXTRACT  SUMBUL  (SOFT). 

Extractum  Sumbul;  Extract  Musk  Root.  1  Gm.  represents 
about  4.5  Gm.  drug.  Used  as  Antispasmodic  and  Nerve 
Tonic,  in  hysterical  conditions,  etc.  Average  Dose:  4  grains 
(0.25  Gm.). 

Extract   Taraxacum   Powdered,   Squibb.       1-oz.  vial 

1  Gm.  represents  about  3  Gm.  drug.  Dose:  10  to  20  grains 
(0.65  to  1.3  Gm.). 

Extract  Taraxacum  Soft*,  Squibb 

glass  jar,          ;   ]/£  lb.  •        ;   oz. 

Extraclum  Taraxaci;  Extract  Dandelion.  I  Gm.  represents  3 
Gm.  Taraxacum,  the  dried  rhizome  and  roots  of  Taraxacum 
officinale.  Bitter  Tonic,  Mild  Laxative.  Average  Dose:  15 
grains  (1  Gm.). 

Extract  Valerian   (Powdered),  Squibb          brittle,  oz. 

1  Gm.  represents  4  Gm.  valerian,  the  dried  rhizome  and  root 
of  Valeriana  officinalis.  Used  as  Antispasmodic  and  Nerve 
Sedative,  in  hysteria  and  other  nervous  excitations.  Dose :  5  to 
15  grains  (0.3  to  1  Gm.). 


The  Squibb  products  are  recognized  everywhere  as  the  Quality 
Standard.  They  are  of  uniform  purity  and  strength,  hence 
therapeutically  dependable.  When  ordering  or  prescribing  med- 
icinal products,  you  will  do  well  always  to  specify  SQUIBB'S. 


88          SQUIBB'S  MATERIA  MEDICA 

Extract  Vanilla  (Flavoring).     See  Tincture  Vanilla. 

EXTRACT  VIBURNUM  PRUNIFOLIUM  (POWDERED). 

Extraclum  Viburni  Prunifolii ;  Extract  Black  Haw.  I  Gm. 
represents  5  Gm.  of  dried  bark  of  Viburnum  pruni- 
folium  or  of  V .  Lentago.  Used  as  Uterine  Sedative  in  dys- 
menorrhea  and  habitual  abortion.  Average  Dose :  8  grains 
(0.5  Gm.). 

EXTRACT  WAHOO.     See   Extract   Euonymus. 

Fehling's  Test  Solution  Elements,  Squibb 

Copper  Sulphate  Solution  500  Cc. 

lOOCc. 

50  Cc. 

Alkaline  Tartrate   Solution  500  Cc. 

Also  supplied   in  a  case,   50  Cc.   of  each  lOOCc. 

solution,   together  with  two  test  tubes  and  50  Cc. 

a  1   Cc.  pipette.     Price,  per  set,  $1.00 

Fennel,  Squibb  tin,  lb. 

Fceniculum.  Dried  ripe  fruit  of  true  Fcem'cu/um  vu/gare  (Fam. 
Umbelh ferae),  carefully  selected.  Aromatic,  Carminative. 
Average  Dose:  15  grains  (1  Gm.). 

FERRIPYRINE. 

Ferropyrine.  Compound  of  36  percent,  ferric  chloride  and 
64  percent,  antipynne.  Yellowish-red  powder,  of  acid-astrin- 
gent taste.  Soluble  in  alcohol,  6  parts  water;  insoluble  in  ether, 
Hematinic,  Styptic.  Dose:  5  to  15  grains  (0.3  to  1  Gm.). 

FlBROLYSIN. 

Sterilized  15  percent,  solution  thiosinamine  and  sodium  sali- 
cylate.  Resolvent,  Discutient.  Dose:  by  hypodermic,  intramus- 
cular or  intravenous  injection,  one  2.3  Cc.  vialful  (  =  0.2  Gm. 
[3  gr.]  thiosinamine)  daily  or  every  second  or  third  day. 

FIG. 

Ficus,  N.  F.  Partially  dried  fruit  of  Ficus  Carlica  (Fam. 
Moraces).  Nutrient,  Laxative, 

FLAXSEED.     See  Linseed. 

Flowers  of  Sulphur.      See  Sulphur  Sublimed. 

Flowers   of  Zinc.         See  Zinc  Oxide. 

Fluid  Aloes  for  Tincture,  Squibb  pint,  ;  J4  pint, 
Three  times  strength  of  Tincture  Aloes  U.  S.  P.  100  mils  (Cc.) 
represent  30  Cm.  purified  aloes  and  60  Gm.  licorice 
root.  For  conveniently  making  Tincture  Aloes  take:  Fluid 
Aloes  Squibb,  Alcohol,  and  Water,  equal  volumes;  mix  the 
alcohol  and  water,  then  add  the  fluid  aloes. 


SQUIBB'S  MATERIA  MEDICA          89 

Fluid  Bay  Laurel,  Squibb  pint,         ;  |4  pint. 

A  concentrated  solution  designed  for  the  extemporaneous  prep- 
aration of  a  superior  bay  rum.  Take:  Fluid  Bay  Laurel 
Squibb.  1  fl.  oz.;  Alcohol  and  Water,  of  each  32  fl.  ozs.  Mix 
the  alcohol  and  fluid  bay  laurel,  and  add  the  water. 

Fluid  Benzoin  for  Tincture,  Squibb  pint,        ;  |4  pinf. 
From  best  quality  Siam  gum  benzoin.     Especially  designed  for 
convenient  preparation  of  Tincture  Benzoin,  by  mixing  4  fl%  ozs. 
of  it  with  12  fl.  ozs.  alcohol. 

Fluid  Benzoin  Compound  for  Tincture,  Squibb 

pint,          ;   ]/4  pint, 

Twice  strength  of  U.  S.  P.  Tincture  Benzoin  Compound. 
Designed  for  rapid  and  convenient  preparation  of  latter,  by 
mixing  with  an  equal  volume  alcohol. 

Fluid  Cantharides  for  Tincture,  Squibb 

pint,          ;   ]/4  pint, 

Prepared  from  best  Russian  Cantharides  (Cantharis  vesica- 
iorid).  2  mils  [Cc.])  represent  1  Gm.  drug.  Designed  for 
convenient  preparation  of  Tincture  Cantharides  by  diluting 
it  with  4  volumes  alcohol.  Antidotes:  flaxseed  tea  or  other 
demulcents,  then  emetics  subcutaneously ;  opium  by  rectum. 
Avoid  oils! 

Fluid  Cardamom  Compound,  Squibb 

pint,          ;  ]/4  pint, 

Designed  for  convenient  preparation  of  Tincture  Cardamom 
Compound  as  follows:  Take  Fluid  Cardamom  Compound, 
Squibb,  4  fl.  ozs.  or  125  mils  (Cc.) ;  Glycerin,  288  min.  or 
18.75  mils;  Diluted  Alcohol,  to  make  16  fl.  ozs.  or  500  mils. 
Mix;  filter  if  necessary. 

Fluid   Cascara  Aromatic   (Non=Alcoholic)    Squibb 

pint          ;  3-oz. 

An  improved,  non-alcoholic  preparation  of  Cascara,  made  from 
best  quality,  well-seasoned  Cascara  Sagrada  bark,  I  mil  (Cc.) 
representing  1  Gm.  of  drug.  An  efficient,  pleasant  Laxative, 
with  but  little  tendency  to  produce  secondary  constipation. 
Dose !  |/4  to  1  teaspoonful,  after  meals  or  at  bedtime. 

Fluid  Cinchona  Compound  for  Tincture,  Squibb 

pint,         ';  ]/4  pint, 

Each  100  mils  (Cc.)  represents  50  Gm.  red  cinchona,  40  Gm. 
bitter-orange  peel  and  10  Gm.  serpentaria,  and  assays  2  to  2.5 
Gm.  of  alkaloids.  To  reduce  this  product  to  strength  of 
Tincture  Cinchona  Compound  U.  S.  P.,  mix  200  mils  of  it 
with  60  mils  glycerin,  540  mils  alcohol  and  200  mils  water; 
filter  if  necessary. 

Since  we  make  only  one  quality  of  each  product,  that  best 
suited  to  the  purposes  intended,  the  specification  "Squibb's" 
is  not  open  to  various  interpretations,  but  has  a  plain,  positive 
meaning.  When  ordering  or  prescribing,  specify  SQUIBB'S. 


90          SQUIBB'S  MATERIA  MEDICA 

Fluid  Eriodictyon  Aromatic,  Squibb 

pint,          ;    '/4   pint, 

Fluid  Yerba  Santa  Aromatic.  Each  minim  represents  approxi- 
mately 1  grain  Eriodictyon.  Convenient  for  the  extempora- 
neous preparation  of  Aromatic  Syrup  Eriodictyon  (Syrup  Cor- 
rigens)  of  National  Formulary,  by  adding  to  32  mils  (Cc.) 
enough  simple  syrup  to  make  1000  mils. 

Fluid    Gambir    Compound,    Squibb 

pint,          ;   '/4  pin'. 

So-called  Fluidextract  Catechu  Compound.  Specially  intended 
for  convenient  preparation  of  compound  tincture  gambir.  100 
mils  (Cc.)  represent  50  Gm.  gambir  and  25  Gm.  Saigon  cinna- 
mon. To  conveniently  make  Tincture  Gambir  Compound  take: 
Fluid  Gambir  Compound  Squibb,  1  volume;  Diluted  Alcohol, 
9  volumes. 

Fluid  Ginger  for  Syrup,  Squibb       pint,         ;  '/4  pint. 

Made  from  best  quality  of  Jamaica  ginger.  Clearly  soluble  in 
simple  syrup.  Intended  for  the  convenient  and  rapid  prepara- 
tion of  Syrup  Ginger,  by  adding  2%  fluidounces  to  29J/g  fluid- 
ounces  of  simple  syrup. 

Fluid  Glycyrrhiza  (Licorice)  for  Quinine,  Squibb 

pint,  ;  1/4  pint, 

Intended  especially  for  masking  the  taste  of  quinine  and  other 
bitter  or  nauseating  remedies.  It  produces  clear  mixtures  with 
syrup,  glycerin  or  water.  It  is  incompatible  with  acids.  For 
conveniently  making  Syrup  Licorice,  take:  Fluid  Licorice 
Squibb,  2  fl.  ozs.;  Syrup,  14  fl.  ozs. 

Fluid   Golden   Seal   Colorless,   Squibb 

•  pint,          ;   YA  P'nt. 

Containing  in  each  16  fluidounces  20  grains  hydrastine  hydro- 
chloride,  in  non-alcoholic  menstruum.  Astringent  and  Anti- 
phlogistic topically;  Tonic  and  Hemostatic  internally.  Used 
externally  in  gonorrhea,  leucorrhea,  endometntis,  etc.,  usually 
in  1  to  2  in  16  dilution;  internally,  in  uterine  hemorrhage, 
chronic  dyspepsia,  internal  hemorrhoids,  etc.  Dose :  15  to  60 
minims  (1  to  4  mils  [Cc.]).  Incompatible  with  alkalies,  borax 
or  tannic  acid.  (1  he  Squibb  laboratories  make  also  the  official 
Fluidextract  Golden  Seal  and  Glycerite  Hydrastis  [so-called 
"non-alcoholic"  fluidextract].) 

Fluid   Hydrastis.      See  Fluid  Golden  Seal  Colorless. 

Fluid  Lavender  Compound  for  Tincture,  Squibb 

pint,  ;    J/4  pint, 

From  oil  lavender  flowers,  oil  rosemary,  Saigon  cinnamon, 
cloves,  nutmeg  and  red  saunders.  Eight  times  strength  of  Tinc- 
ture Lavender  Compound.  For  conveniently  making  latter, 
take:  Fluid  Lavender  Compound,  Squibb,  2  fl.  ozs.;  Alcohol, 
lOj/2  fl.  ozs.;  Water,  3J/?  fl.  ozs.  Mix  th«  alcohol  and  water, 
then  add  the  fluid  lavender  compound. 


SQUIBB'S  MATERIA  MEDICA         91 

Fluid  Licorice  for  Quinine.     See  Fluid  Glycyrrhiza. 

Fluid  Rhubarb  Aromatic  for  Syrup,  Squibb 

pint,          ;   )/4  pint, 

For  conveniently  making  Syrup  Rhubarb  Aromatic,  take  of  this 
Fluid  1  fl.  oz.  and  Syrup  19  fl.  ozs. 

Fluid  Rhubarb  Aromatic  for  Tincture,  Squibb 

pint,          ;   '/4  pint, 

For  conveniently  making  Tincture  Rhubarb  Aromatic,  take: 
Fluid  Rhubarb  Aromatic  Squibb,  5  fl.  ozs.;  Alcohol,  5  fl.  ozs.; 
Water,  4  fl.  ozs.;  Glycerin,  1  fl.  oz.  Mix  the  alcohol,  water 
and  glycerin,  then  add  the  fluid  rhubarb  aromatic. 

Fluid  Rose  Soluble,  Squibb  pint,         ;  '/4  pint, 

Designed  for  the  extemporaneous  preparation  of  rose  water,  by 
diluting  it  with  31  volumes  distilled  water. 

Fluid  Tolu  for  Syrup  (1:19),  Squibb 

pint,          ;   Vi  pinl. 

Solution  Tolu  for  Syrup.  For  the  easy  manufacture  of  Syrup 
Tolu,  by  diluting  it  with  19  volumes  syrup. 

Fluid  White  Pine  Compound,  Squibb 

pint,          ;   YA  pi"*. 

1000  mils  (Cc.)  represent  340  Gm.  each  white  pine  and  wild 
cherry  barks,  40  Gm.  each  spikenard  root  and  balm  gilead  buds, 
32  Gm.  sangumana.  28  Gm.  sassafras  and  24  mils  chloroform. 
Specially  designed  for  conveniently  preparing  Syrup  White 
Pine  Compound,  by  mixing  1  volume  of  it  with  3  volumes 
syrup.  To  make  Syrup  White  Pine  Compound  ivilh  Mor- 
phine of  N.  F.  strength,  add  1/g  grain  morphine  sulphate  per 
fl.  oz.  syrup  white  pine  compound. 

Fluid  Wild  Cherry  for  Syrup,  Squibb 

pint,  ;   }/4  pint, 

Specially  designed  for  the  convenient  and  rapid  preparation  of 
Syrup.  Wild  Cherry,  by  mixing  1  volume  of  it  with  3  volumes 
syrup. 

Fluid     Yerba     Santa     Aromatic.       See     Fluid     Eriodictyon 
Aromatic. 


The  founder  of  the  House  of  Squibb,  Dr.  Edward  R.  Squibb, 
not  only  had  high  ideals,  but  lived  and  labored  for  them;  and, 
in  the  words  of  William  Miller  Bartlett,  "the  House  of  Squibb 
stands  today  as  a  living  monument  to  the  honor,  integrity,  zeal 
and  devotion  of  its  founder." 


92          SQUIBB'S  MATERIA  MEDICA 
FLUIDEXTRACTS. 

The  constantly  growing  recognition  of  the  certainty  of  thera- 
peutic action  of  the  officially  made  fluidextracts,  from  properly 
selected  material,  urges  us  to  be  more  pressing  in  the  presenta- 
tion of  these  products.  In  a  fluidextract  the  active  principles 
are  directly  available,  so  that  the  value  of  these  preparations  in 
medicine  is  not  in  doubt.  A  selection  of  the  most  active  drugs 
offered  by  the  market  or  obtained  by  direct  importation  from 
best  sources,  and  a  thorough  exhaustion  of  the  assayed  and  tested 
drug,  assure  the  production  of  fluidextracts  of  a  standard 
strength,  containing  the  maximum  amount  of  active  principle 
and  accurately  representing  the  drug.  The  process  of  extrac- 
tion employed  is  the  well-known  repercolalion  process,  which 
originated  in  the  Squibb  Laboratories.  The  menstrua  used  are 
those  which  most  effectively  extract  the  medicinal  ingredients  of 
the  drugs  and  thus  are  theoretically  true  solvents  of  them.  The 
strength  of  the  alcohol  in  these  fluidextracts  is  fully  equal  to 
the  requirements  of  the  U.  S.  P.,  hence  when  deposits  are 
discovered  they  may  be  considered  as  inert  if  all  the  self- 
evident  precautions  against  evaporation,  heat,  etc.,  have  been 
taken  by  the  purchaser.  In  a  considerable  number  of  cases 
the  pharmacopoeia  prescribes  a  definite  assayed  alkaloidal 
strength  of  the  fluidextracts,  and  to  this  standard  they  are 
therefore  accurately  adjusted.  Otherwise,  1  mil  (Cc.)  repre- 
sents 1  Gm.  of  the  drug.  Fluidextract  Cannabis  is  officially 
required  to  be  assayed  biologically;  and  we  physiologically  assay 
also  those  which  the  U.  S.  P.  recommends  being  so  tested. 

Fluidextract  Aconite,  Squibb  pint,         ;  gal. 

Fluidextraclum  Aconiii.  From  dried  tuberous  root  of  genuine 
Aconilum  Napellus.  Required  by  U.  S.  P.  to  assay  0.45  to 
0.55  Gm.  ether-soluble  alkaloids  per  100  mils  (Cc.). 
Physiologically  assayed  by  U.  S.  P.  method ;  minimum  lethal 
dose  not  more  than  0.0004  nor  less  than  0.00032  mil  per 
Gm.  weight  of  guinea-pig.  Sedative,  Febrifuge,  Sudorific, 
Antineuralgic.  Average  Dose:  '/2  minim  (0.03  mil).  Antidotes: 
tannin,  then  emetics;  atropine,  digitalis  or  ammonia;  smalk  often 
repeated  doses  of  stimulants;  artificial  respiration,  if  required. 

FLUIDEXTRACT  ADONIS. 

Fluidexlraclum  Adonidis,  N.  F. ;  Fluidextract  Bird's  Eye. 
From  dried  root  of  Adonis  'Vernalis.  Cardiac  Stimulant,  of 
digitalis  group.  Average  Dose:  2  minims  (0.13  mil  [Cc.]). 
Antidotes:  emetics;  stimulants;  opium  to  control  gastro-intestinal 
symptoms. 

Fluidextract  Aletris,  Squibb  pint,         ;  %  pint, 

Fluidextractum  Aletridis,  N.  F.;  Fluidextract  Stargrass  or  Star- 
wort.  From  dried  rhizome  of  Aletris  farinosa.  Simple  Bitter, 
also  used  as  Uterine  Tonic;  in  amenorrhea,  rheumatism,  flatu- 
lent dyspepsia,  etc.  Average  Dose :  30  minims  (2  mils 
[Cc.]). 


SQUIBB'S  MATERIA  MEDICA         93 

FLUIDEXTRACT  ANGELICA  ROOT. 

Fluid  extractum  Angelica  Radicis,  N.  F.  From  dried  rhizome 
and  roots  of  Angelica  alropurpurea  (Fam.  Umbelli  feres). 
Stimulating  Expectorant,  like  tolu.  Average  Dose :  30  minims 
(2  mils  [Cc.]). 

FLUIDEXTRACT  APOCYNUM. 

Fluidextractum  Apocyni,  N.  F.;  Fluidextract  Canadian  Hemp. 
From  dried  rhizome  of  Apocynum  cannabinum.  Cardiac 
Tonic,  of  digitalis  group;  unreliable  as  to  rate  of  absorption. 
Average  Dose:  12  minims  (0.75  mil  [Cc.]). 

FLUIDEXTRACT  ARALIA. 

Fluidexlracium  Aralics,  N.  F.;  Fluidextract  Spikenard.  From 
dried  root  of  Aralia  racemosa.  Used  as  Alterative,  Dia- 
phoretic. Average  Dose:  30  minims  (2  mils  [Cc.]). 

FLUIDEXTRACT    ARBOR    VITAE.      See    Fluidextract    Thuja. 

Fluidextract  Arnica  Flowers,  Squibb 

pint,          ;   ]4   pint, 

Fluid  ex  iractum  Arnica,  N.  F.  From  dried  flower-heads  of 
Arnica  montana.  Feeble  Rubefacient  externally;  Alterative 
internally,  in  chronic  rheumatism,  catarrhs,  nephritis,  etc. 
Average  Dose:  12  minims  (0.75  mil  [Cc.]). 

FLUIDEXTRACT  AROMATIC  POWDER. 

FluiJexlracium  Aromalicum.  Each  mil  (Cc.)  represents  1  Gm. 
of  mixture  of  Saigon  cinnamon  (35),  ginger  (35),  cardamom 
(15)  and  nutmeg  (15).  Aromatic,  Carminative.  Average 
Dose:  15  minims  (1  mil  [Cc.]). 

Fluidextract  Asclepias,  Squibb  pint,         ;  %  pint, 

Fluidextraclum  Asclepiadis,  N.  F.;  Fluidextract  Pleurisy  Root. 
From  dried  root  of  Asclepias  tuberosa.  Used  as  Diaphoretic; 
in  pleurisy,  bronchitis,  colic,  etc.  Average  Dose :  30  minims  (2 
mils  [Cc.]). 

Fluidextract  Aspidosperma,  Squibb 

pint,  ;    ]/4    pint, 

FluiJextractum  Aspijospermalis ;  Fluidextract  Quebracho. 
From  dried  bark  of  Aspidosperma  Quebracho  bianco.  Respira- 
tory Tonic,  Antispasmodic;  chiefly  in  asthma  and  emphysema. 
Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 


The  Squibb  Ideals  have  taken  concrete  form  in  the  Squibb 
Products;  these  are  universally  recognized  as  standards  of 
uniform  Purity  and  Efficacy,  that  is,  general  Excellence  and 
Reliability.  Specify  SQUIBB'S  when  prescribing  or  ordering. 


94         SQUIBB'S  MATERIA  MEDICA 

FLUIDEXTRACT  BAPTISIA. 

Fluidextractum  Baptisiee,  N.  F.;  Fluidextract  Wild  Indigo. 
From  dried  root  of  Baplisia  iinctoria.  Astringent.  Used  ex- 
ternally in  ulcers,  sore  throat,  etc.;  internally,  chiefly  in  typhoid 
fever.  Average  Dose:  15  minims  (1  mil  [Cc.]). 

FLUIDEXTRACT  BEARBERRY.    See  Fluidextract  Uva  Ursi. 

Fluidextract  Belladonna  Leaves,  Squibb 

pint,          ;    |/4   pint, 

From  dried  leaves  and  tops  of  Atropa  Belladonna.  Assays 
about  0.35  Gm.  alkaloids  in  100  mils  (Cc.).  Anodyne,  Anti- 
spasmodic,  Antithydrotic.  Dose:  1  to  2  minims  (0.06  to  0.13 
mil).  Antidotes:  tannin,  then  emetics;  morphine;  pilocarpine; 
physotigmine;  aconitine. 

Fluidextract  Belladonna  Root,  Squibb 

pint,          ;   1/4  pint, 

Fluidexiracium  Belladonna;  Radicis.  Assays  0.405  to  0.495 
Gm.  alkaloids  in  100  mils  (Cc.).  Average  Dose:  1  minim 
(0.06  mil). 

Fluidextract  Berberis,  Squibb  pint,         ;  '74  pint, 

Fluidextractum  Berberidis,  N.  F.;  Fluidextract  Barberry. 
From  dried  rhizome  and  roots  of  Berberis  Aquifolium  and 
other  species  of  Berberis.  Used  as  Bitter  Tonic  and  Altera- 
tive; in  anorexia,  general  debility,  jaundice,  etc.  Average 
Dose:  30  minims  (2  mils  [Cc.]). 

Fluidextract   Beth   Root.      See  Fluidextract  Trillium. 
FLUIDEXTRACT  BIRD'S  EYE.     See  Fluidextract  Adonis. 

FLUIDEXTRACT   BITTERSWEET. 

Fluid extraclum  Dulcamara:,  N.  F.  From  dried  young  branches 
of  Solanum  Dulcamara.  Used  as  Alterative  in  skin  diseases, 
leprosy,  rheumatism,  etc.  Average  Dose :  1  fluidrachm  (4  mils 
[Cc.]). 

FLUIDEXTRACT  BLACKBERRY.    See  Fluidextract  Rubus. 
Fluidextract   Black   Cohosh.     See  Fluidextract  Cimicifuga. 
FLUIDEXTRACT  BLADDER- WRACK.     See  Fluidextract  Fucus. 
FLUIDEXTRACT   BLOODROOT.     See   Fluidextract  Sanguinaria. 

FLUIDEXTRACT  BLUE  FLAG. 

Fluidexlractum  IriJis  V ersicoloris,  N.  F.  From  dried  rhizome 
of  Iris  •versicolor.  Cathartic,  similar  to  podophyllum.  Average 
Dose:  30  minims  (2  mils  [Cc.]). 


SQUIBB'S  MATERIA  MEDICA         95 

FLUIDEXTRACT  BOLDO. 

Fluid  ex  traclum  Boldi,  N.  F.  From  dried  leaves  of  Boldu 
Boldus.  Aromatic,  mild  Diuretic.  Average  Dose :  8  minims 
(0.5  mil  [Cc.]). 

FLUIDEXTRACT   BONESET.    See   Fluidextract   Eupatorium. 
FLUIDEXTRACT    BROOM    TOPS.     See    Fluidextract    Scoparius. 

Fluidextract   Bryonia,  Squibb  pint,         ;  14  pint, 

From  dried  roots  of  Bryonia  alba.  Drastic  resinous  Cathartic. 
Dose:  10  to  30  minims  (0.6  to  2  mils  [Cc.]). 

Fluidextract   Buchu,   Squibb  pint,         ;  |4  pint, 

Fluidexlractum  Buchu.  From  best  quality  short  buchu  leaves 
(Barosma  betulina).  Diuretic,  Anticatarrhal ;  chiefly  in  urin- 
ary disorders.  Average  Dose:  30  minims  (2  mils  [Cc.]). 

Fluidextract  Buchu  Compound,  Squibb 

pint,          ;  ]/4  pint, . 

Fluid extraclum  Buchu  Compositum,  N.  F.  Each  fluidounce 
represents  about  285  grains  short  buchu  and  57  grains  each  of 
cubeb,  juniper  and  uva  ursi.  Diuretic,  Urinary  Anticatarrhal. 
Average  Dose:  30  minims  (2  mils  [Cc.]).  _- 

Fluidextract   Buckthorn   Bark.      See  Fluidextract  Frangula. 

FLUIDEXTRACT  BUCKTHORN  BERRIES.     See  Fluidextract  Rhamnus 
Cathartica. 

Fluidextract    Burdock.     See  Fluidextract  Lappa. 
FLUIDEXTRACT  BUTTERNUT.    See  Fluidextract  Juglans. 

FLUIDEXTRACT  CALENDULA. 

Fluidextraclum  Calendula,  N.  F.;  Fluidextract  Marigold. 
From  flowering  herb  of  Calendula  officinalis.  Used  externally, 
on  bruises,  wounds,  etc.  (pure  or  diluted). 

Fluidextract  Calumba,  Squibb  pint,         ;  %  pint, 

Fluid  exlraclum  Calumbce,  N.  F.;  Fluidextract  Columbo. 
Dropped  from  U.  S.  P.  From  dried  root  of  Jateorrhiza  pal- 
mala.  Bitter  Tonic,  Stomachic.  Average  Dose:  30  minims  (2 
mils  [Cc.]). 

FLUIDEXTRACT  CANADIAN  HEMP.     See  Fluidextract  Apocynum. 


The  Squibb  Label  on  a  package  is  a  positive  guaranty  for  the 
uniform  Purity  and  Reliability  of  the  product.  We  make  only 
ONE  quality:  the  SQUIBB  quality;  and  our  prices  are  as  low 
as  they  can  be  made  for  that  quality.  Specify  SQUIBB'S. 


96          SQUIBB'S  MATERIA  MEDICA 

Fluidextract   Cannabis   Squibb  pint,         ;  J4  pint, 

Fluidexlractum  Cannabis,  From  dried  flowering  tops  of  pistillate 
plants  of  Cannabis  saliva  or  variety  inJica.  Physiologically 
assayed  according  to  U.  S.  P.;  incoordination  produced  by 
0.03  mil  (Cc.)  per  Kgm.  weight  of  dog.  Sedative.  Anodyne. 
Average  Dose:  \Yi  minims  (0.1  mil).  Antidotes:  atropine; 
strychnine;  caffeine;  hot,  strong  coffee. 

Fluidextract  Capsicum,  Squibb  pint,  ;  %  pint, 
Fluidextractum  Capsici,  U.  S.  P.  VHIth  Rev.  From  dried 
ripe  fruits  of  Capsicum  frutescens.  Carminative,  Stomachic; 
occasionally  used  externally  (diluted,  in  sore  throat).  Average 
Dose:  1  minim  (0.06  mil  [Cc.]),  well  diluted.  Antidotes: 
demulcents,  antiphlogistics;  morphine  for  pain. 

Fluidextract     Cardamom    Compound.       See     Fluid    Car- 
damom Compound.  pint,          ;  '74  pint, 

©  Fluidextract  Cascara  Sagrada,  Squibb 

pint,          ;  '74  pint, 

Fluidextractum  Cascarce  Sagradce.  From  select,  thoroughly 
seasoned,  dried  bark  of  trunk  and  branches  of  Rhamnus 
Purshiana.  No  additions  or  alterations  have  been  made  in  this 
official  fluidextract,  for  the  purpose  of  enhancing  its  activity 
or  maskin'g*  or  eliminating  its  characteristic  odor  and  taste — a 
not  uncommon  practice.  Laxative,  acting  mainly  on  colon; 
has  but  little  tendency  to  produce  secondary  constipation. 
Average  Dose:  15  minims  (1  mil  [Cc.]). 

©  Fluidextract   Cascara  Sagrada  Aromatic,   Squibb 

pint,          ;  ]/4  pint, 

Fluidextractum  Cascarce  Sagrada  Aromalicum.  From  thor- 
oughly seasoned  Cascara  Sagrada  bark,  sweetened  and  flavored. 
While  all  the  active  constituents  are  preserved,  the  disagreeable 
bitter  principles  are  eliminated.  It  has  not  had  any  other  pur- 
gative agent  added  to  it.  Average  Dose:  30  minims  (2  mils). 
(See  also  Fluid  Cascara  Aromatic  [Non-AIcohoiic] .) 

Fluidextract   Castanea,   Squibb.  pint,         ;  74  pint. 

Fluidexlraclum  Castanece,  N.  F.;  Fluidextract  Chestnut  Leaves. 
From  dried  leaves  of  Castanea  dentala.  Astringent,  but  used 
chiefly  in  whooping  cough.  Average  Dose :  1  fluidrachm 
(4  mils  [Cc.]). 

Fluidextract  Catechu  Compound.     See  Fluid  Gambir  Com- 
pound. 

FLUIDEXTRACT  CATNEP. 

Fluidcxtraclum  Catariae,  N.  F.  From  herb  of  Nepela  Calaria. 
Aromatic  Carminative,  similar  to  peppermint.  Average  Dose: 
1  fluidrachm  (4  mils  [Cc.]). 


SQUIBB'S  MATERIA  MEDICA         97 

FLUIDEXTRACT  CAULOPHYLLUM. 

Fluidexlracium  Caulophylli,  N.  F.;  Fluidextract  Blue  Cohosh. 
From  dried  rhizome  and  rootlets  of  Caulophyllum  lhaliclroides. 
Used  as  Diuretic  and  Emmenagogue.  Average  Dose :  8  minims 
(0.5  mil  [Cc.]). 

Fluidextract  Celery,  Squibb  pint,         ;  |4  P"1*. 

Fluidexlraclum  Apii  Fructus,  N.  F.  From  seed  of  Apium 
graveolens.  Used  as  Emmenagogue.  Average  Dose:  30  minims 
(2  mils  [Cc.]). 

Fluidextract   Chestnut   Leaves.      See  Fluidextract  Castanea. 

FLUIDEXTRACT  CHIMAPHILA. 

Fluidexlraclum  Chimaphilee,  N.  F.;  Fluidextract  Pipsissewa. 
From  dried  leaves  of  Chimaphila  umbellala.  Used  as  Tonic, 
Astringent,  Diuretic.  Average  Dose:  30  minims  (2  mils 
[Cc.]). 

FLUIDEXTRACT  CHIONANTHUS. 

Fluidextraclum  Chionanlhi,  N.  F.;  Fluidextract  Fringe  Tree 
Bark.  From  dried  bark  of  root  of  Chionanthus  virginica. 
Used  as  Alterative  and  Aperient.  Average  Dose:  30  minims 
(2  mils  [Cc.]). 

FLUIDEXTRACT  CHIRATA. 

Fluidexlractum  Chirala,  N.  F.;  Fluidextract  Chiretta.  From 
dried  plant  of  Swerfia  Chirayila.  Bitter  Stomachic,  similar 
to  gentian.  Average  Dose:  15  minims  (1  mil  [Cc.]). 

Fluidextract  Cimicif  uga,  Squibb         pint,         ;  %  pint, 

Fluidextractum  Cimicif ugas;  Fluidextract  Black  Cohosh.  From 
dried  rhizome  and"  roots  of  Cimicifuga  racemose.  Used  as 
Alterative,  Sedative,  Emmenagogue.  Average  Dose:  15 
minims  (1  mil  [Cc.]). 

Fluidextract  Cinchona,  Squibb  pint,         ;  %  pint, 

Fluidexlraclum  Cinchona.  Assays  4  to  5  Gm.  alkaloids  in 
100  mils  (Cc.)  ;  contains  10  vol.  percent,  glycerin.  Antiperiodic, 
Bitter  Tonic.  Average  Dose:  15  minims  (1  mil). 

FLUIDEXTRACT  CINCHONA  AQUEOUS. 

Fluidexlraclum  Cinchonce  Aquosum,  N.  F.  100  mils  (Cc.) 
yield  about  5  Gm.  alkaloids.  Bitter  Tonic,  Antiperiodic. 
Average  Dose:  15  minims  (1  mil  [Cc.]). 


This  house  supplies  only  one  quality  of  each  product:  that  best 
suited  to  the  purposes  intended.  The  specification  "Squibb's" 
is  not  open  to  various  interpretations;  it  has  a  plain,  posi- 
tive meaning.  Therefore,  when  prescribing,  specify  SQUIBB'S. 


98          SQUIBB'S  MATERIA  MEDICA 

Fluidextract  Cinchona  Red,  Compound.     See  Fluid  Cin- 
chona Compound. 

FLUIDEXTRACT  COCILLANA. 

Fluidexlractum  Cocillance,  N.  F.  From  dried  bark  of  Guarea 
Rusbyi  (Fam.  Mellaceoi).  Nauseant  Expectorant,  similar  to 
ipecac.  Average  Dose:  15  minims  (1  mil  [Cc.J). 

Fluidextract  Coffee  Roasted,  Squibb 

pint,          ;  J/4  pint, 

Fluid  exiractum  Coffees,  N.  F.  Designed  for  those  desiring  the 
Tonic  and  Stimulant  effects  of  coffee  in  concentrated  form. 
Average  Dose:  30  minims  (2  mils  [Cc.]). 

Fluidextract  Colchicum  Root,  Squibb 

pint,          ;  '/4  pint, 

Fluidexlractum  Colchici  Cormi,  N.  F.  From  dried  corm  of 
Colchicum  aulumnale.  Assays  0.31  to  0.39  Gm.  colchicine  in 
each  100  mils  (Cc.)  (about  Vsoo  grain  colchicine  in  1  minim). 
Antipodagric,  Antineuralgic,  Alterative.  Average  Dose:  3 
minims  (0.2  mil).  Antidotes:  lannin,  then  emetics;  opiates  for 
pain  and  diarrhea;  hot,  strong  coffee  and  other  stimulants. 

Fluidextract  Colchicum  Seed,  Squibb 

pint,          ;  ]/4  pint. 

Fluidexlracium  Colchici  Seminls.  Assays  0.36  to  0.44  Gm. 
colchicine  in  100  mils  (Cc.).  Average  Dose:  3  minims  (0.2 
mil).  Antidotes:  as  of  preceding. 

Fluidextract    Columbo.     See  Fluidextract  Calumba. 

Fluidextract  Condurango,  Squibb      pint,         ;  %  pint, 
FluiJextracium  Condurango,  N.  F.     From  dried  bark  of  Mars- 
denia    Condurango.      Bitter    Stomachic;    chiefly    in    ulcer    and 
cancer    of    stomach.      Average    Dose :    1     fluidrachm    (4    mils 
[Cc.]). 

Fluidextract  Conium,  Squibb  pint,         ;  %  pint, 

Fluidextraclum  Conli,  N.  F.;  Fluidextract  Hemlock  Seed. 
From  fruit  of  Conium  maculatum.  Assays  0.35  to  0.45  Gm. 
coniine  in  100  mils  (Cc.).  Antispasmodic,  Sedative.  Average 
Dose:  3  minims  (0.2  mil).  Antidotes:  tannin,  then  emetics; 
atropine  or  strychnine  hypodermically ;  caffeine  or  other 
stimulants. 

FLUIDEXTRACT  CONVALLARIA  FLOWERS. 

Fluidextraclum  Convallarice  Florum,  N.  F.;  Fluidextract  Lily 
of  the  Valley  Flowers.  From  flowers  of  Convallarla  majalis. 
Cardiac  Tonic,  similar  to  digitalis.  Average  Dose :  8  minims 
(0.5  mil  [Cc.]). 


SQUIBB'S  MATERIA  MEDICA          99 

FLUIDEXTRACT  CONVALLARIA  ROOT. 

Fluidextraclum  ConVallarice  Radios,  N.  F. ;  Fluiclextract  Lily 
of  the  Valley  Root.  Heart  tonic,  similar  to  digitalis.  Aver* 
age  Dose:  8  minims  (0.5  mil  [Cc.]). 

FLUIDEXTRACT  COPTIS. 

Fluidextractum  Coptis,  N.  F.;  Fluidextract  Gold  Thread. 
From  dried  plant  of  Coptis  trifolia.  Bitter  Tonic.  Average 
Dose:  30  minims  (2  mils  [Cc.]). 

Fluidextract  Corn  Silk.     See  Fluidextract  Zea. 

FLUIDEXTRACT  CORN  us. 

Fluidexlraclum  Corni,  N.  F. ;  Fluidextract  Dogwood.  From 
bark  of  root  of  Cornus  florida.  Astringent,  Antiperiodic ; 
practically  obsolete.  Average  Dose :  30  minims  (2  mils 
[Cc.]). 

FLUIDEXTRACT  CORYDALIS. 

FluiJextractum  Corydalls,  N.  F. ,  Fluidextract  Turkey  Corn. 
From  dried  tubers  of  Bicuculla  canadensis.  Used  as  Antiluetic, 
but  considered  useless  and  therefore  harmful  by  Council  on 
P.  &  C.  of  A.  M.  A.  Average  Dose:  10  minims  (0.65  mil 
[Cc.]). 

FLUIDEXTRACT  GOTO.     See  Fluidextract  Paracoto. 

Fluidextract   Cotton   Root   Bark,  Squibb 

pint,          ;   ]/4  pint, 

Fluid ex tracium  Cossypii  Corticis,  N.  F.;  Fluidextract  Gossy- 
pium.  From  dried  bark  of  root  of  Cossypium  herbaceum  and 
other  species  of  Cossppium.  Used  as  Emmenagogue.  Aver* 

age  Dose:  30  minims  (2  mils   [Cc.]). 
Fluidextract    Couch    Grass.      See    Fluidextract   Triticum. 

Fluidextract     Cramp     Bark.     See     Fluidextract     Viburnum 
Opulus. 

FLUIDEXTRACT  CRANESBILL.     See   Fluidextract  Geranium. 

Fluidextract  Cubeb,  Squibb  pint,         ;  '/4  pint, 

Fluidexlraclum  Cubebce,  N.  F.  From  dried  fruits  of  Piper 
Cubeba.  Diuretic,  Sedative,  Stimulating  Expectorant.  Average 
Dose:  15  minims  (1  mil  [Cc.]). 

FLUIDEXTRACT  CULVER'S   ROOT.     See   Fluidextract   Leptandra. 


The  prices  of  the  Squibb  Products  are  in  all  instances  as  low  as 
the  quality  and  quantity  of  ingredients  and  the  expense  of  man- 
ufacture allow.  They  include  containers,  packing  and  boxing.  When 
ordering  or  prescribing  medicinal  products,  specify  SQUIBB'S. 


100       SQUIBB'S  MATERIA  MEDICA 

Fluidextract  Cypripedium,  Squibb     pint,        ;  %  pint, 

Fluidextraclum  Cypripedii,  N.  F.;  Fluidextrat*  Ladies'  Slipper. 
From  dried  rhizome  and  roots  of  Cypripedium  hirsutum  and 
other  species  of  Cypripedium.  Used  as  Nerve  Stimulant  and 
Tonic;  in  hypochondriasis,  neuralgia,  etc.  Average  Dose:  15 
minims  (I  mil  [Cc.]). 

Fluidextract  Damiana,  Squibb          pint,         ;  |4  pint. 
Fluidextraclum  Damiante,  N.  F.     From  leaves  of  Tumera  mi- 
crophylla.      Used    as    Nerve    Tonic    and    Aphrodisiac.      Aver- 
age  Dose:  30  minims   (2  mils    [Cc.]). 

Fluidextract    Dandelion.      See    Fluidextract    Taraxacum. 

Fluidextract  Digitalis,  Squibb  pint,         ;  '/£  pint, 

Fluidextraclum  Digilalis ;  Fluidextract  Foxglove.  From  best 
quality,  select  Digitalis,  the  dried  leaves  of  Digitalis  pur- 
purea.  Physiologically  assayed  according  to  U.'  S.  P.,  and 
standardized;  minimum  lethal  dose  not  more  than  0.0006  mil 
(Cc.)  per  Gm.  weight  of  frog.  Also  assayed  by  "cat  method" 
of  Hatcher,  for  those  who  desire  to  administer  it  by  Eggleston 
method.  Direct  Cardiac  Stimulant,  Diuretic.  Most  effective 
when  heart  is  rapid  and  very  irregular;  of  avail  in  edema 
only  when  latter  arises  from  impaired  circulation.  Naturally 
apt  to  cause  gastro-intestinal  disturbance.  Average  Dose:  1 
minim  (0.06  mil  [Cc.]).  Antidotes:  tannin,  emetics;  nitro- 
glycerin,  strychnine  or  alcohol;  morphine;  rest  in  horizontal 
position. 

Fluidextract    Dioscorea,   Squibb          pint,         ;  %  pint, 

Fluidextraclum  Dioscoreae,  N.  F.;  Fluidextract  Wild  Yam\ 
From  dried  rhizome  of  Dioscorea  villosa.  Used  in  colic  and 
other  abdominal  irritation.  Average  Dose :  1  fluidrachm  (4 
mils  [Cc.]). 

Fluidextract  Dog  Grass.     See  Fluidextract  Triticum. 
FLUIDEXTRACT  DOGWOOD.     See  Fluidextract  Cornus. 

Fluidextract  Dogwood,  Jamaica.      See  Fluidextract  Jamaica 
Dogwood. 

FLUIDEXTRACT  DROSERA. 

Fluidextractum  Droserce,  N.  F.;  Fluidextract  Sundew.  From 
air-dried  flowering  plant  of  Drosera  rotundifolia,  D.  intermedia 
or  D.  long! folia  (Fam.  Droseracece) ,  Used  in  respiratory 
diseases;  no  established  indications  for  its  use.  Average  Dose: 
60  minims  (4  mils  [Cc.]). 

FLUIDEXTRACT  DULCAMARA.     See  Fluidextract  Bittersweet. 

Fluidextract  Echinacea,  Squibb       pint,         ;    '4   pint, 

Fluidextraclum  Echinacete,  N.  F.  From  dried  root  of  Echin- 
acea anguslifolia.  Used  as  Alterative  and  Antiluetic  internal- 
ly, Antiseptic  and  snakebite  antidote  externally.  Averag' 
Dose:  15  minims  (1  mil  [Cc.]). 


SQUIBB'S  MATERIA  MEDICA        101 

Fluidextract   Ergot,   Squibb         pint,         ;    J4  piQt> 

oz.         ;  J/2  oz. 

The  original  Squibb  Fluidextract  Ergot,  U.  S.  P.,  1860.  It 
has  been  proved  that  much  of  the  value  of  fluidextract  ergot 
depends  upon  the  selection  of  the  best  ergot  obtainable  irre- 
spective of  cost,  its  thorough  cleansing  and  preparation, 
and  care  in  percolation.  Spanish  rye  ergot  is  very 
superior  in  activity  to  any  other  kind,  and  should  be  used 
exclusively.  Ergot  from  barley,  wheat  or  oats,  although  show- 
ing some  activity,  is  much  inferior  to  that  from  rye,  and  the 
peculiar  atmospheric  conditions  of  the  Spanish  peninsula  tend 
to  the  more  mature  and  better  growth  of  this  fungus.  The 
cleansing  of  ergot  is  of  greatest  importance,  since  the  bags  or 
cases  in  which  the  drug  is  imported  often  contain  wormeaten 
and  absolutely  worthless  material  and  dirt,  nails,  tacks,  and 
hair  pins,  dropped  apparently  by  the  women  who  pick  the  ergot. 
After  the  worthless  and  foreign  matter  is  all  removed,  the  ergot 
is  ground  and  transferred  to  the  percolators  and  the  active  prin- 
ciples extracted  by  the  Squibb  repercolation  process,  with  men- 
struum of  diluted  alcohol  and  a  little  acetic  acid,  whereby  a 
fluidextract  is  obtained  which  accurately  represents  the  drug 
mil  (Cc.)  for  Gm.  Squibb's  Fluidextract  Ergot  is  physi- 
ologically tested  by  the  method  of  Edmunds  and  Hale,  and 
proved  of  standard  activity;  hence  therapeutically  dependable. 
Emmenagogue,  Oxytocic,  Vaso-constrictor,  Circulatory  Equal- 
izer. Average  Dose:  30  minims  (2  mils).  Acts  in  15  minutes; 
effect  continues  only  about  ]/2  hour. 


Fluidextract  Eriodictyon,  Squibb       pint,         ;  %  pint, 

Fluidexiraclum  ErioJictyi ;  Fluidextract  Yerba  Santa.  From 
dried  leaves  of  Eriodiclyon  calif ornicum.  Used  as  Anticatarrhal, 
Expectorant;  in  coughs,  genito-urinary  inflammations,  etc.,  but 
used  chiefly  to  disguise  quinine  and  other  unpleasant  drugs. 
Average  Dose:  15  minims  (1  mil  [Cc.]). 

FLUIDEXTRACT  EUCALYPTUS. 

Fluidextractum  Eucalypti.  From  dried  leaves  of  Eucalyplus 
Clobulus.  Antiperiodic,  Tonic.  Average  Dose:  30  minims  (2 
mils  [Cc.]). 

FLUIDEXTRACT  EUONYMUS. 

FluiJextractum  Euonymi,  N.  F.;  Fluidextract  Wahoo.  From 
root-bark  of  Euonymus  airopurpureus.  Cathartic.  Average 
Dose:  8  minims  (0.5  mil  [Cc.]). 


jf  difficulty  is  experienced  in  procuring  any  Squibb  product, 
in  the  original  packages  here  listed,  please  notify  us;  we 
shall  see  that  your  wants  are  met  promptly  and  satisfactorily. 


102        SQUIBB'S  MATERIA  MEDICA 

FLUIDEXTRACT  EUPATORIUM. 

Fluidexlracium  Eupatoril,  N.  F.;  Fluidextract  Boneset.  From 
dried  leaves  and  flowering  tops  of  Eupatorium  perfoliatum. 
Used  as  Diaphoretic.  Average  Dose:  30  minims  (2  milt 
[Cc.]). 

FLUIDEXTRACT  EUPHORBIA  PILULIFERA. 

Fluldexfractum  Euphorbia  Piluliferce,  N.  F.  From  dried  herb 
of  Euphorbia  pilulifera  (Fam.  Euphorbiacece).  Used  mainly 
in  asthma  and  chronic  bronchitis.  Average  Dose:  30  minims 
(2  mils  [Cc.]). 

FLUIDEXTRACT  FALSE  UNICORN.     See  Fluidextract  Helonias. 
Fluidextract   Foxglove.      See  Fluidextract  Digitalis. 

Fluidextract  Frangula,  Squibb   *        pint,         ;  J4  pint, 
Fluidextractum      Frangula;      Fluidextract      Buckthorn      Bark. 
From  dried  bark  of  Rhamnus  Frangula.     Laxative.     Average 
Dose:  15  minims  (1  mil  [Cc.]). 

FLUIDEXTRACT  FROST- WEED.     See  Fluidextract  Helianthemum. 

FLUIDEXTRACT  Fucus. 

Fluiilextractum  Fuci,  N.  F.;  Fluidextract  Bladder- Wrack, 
from  thallus  of  Fucus  vesiculosus.  Used  as  Alterative  in  goiter 
and  rurberculous  glands  chiefly.  Average  Dose :  according  to  N. 
F.,  10  minims  (0.6  mil  [Cc.]);  other  authorities  state  30  to  120 
minims  (2  to  8  mils). 

FLUIDEXTRACT  GALEGA. 

Fluid exlracium  Calega,  N.  F.  From  dried  flowering  tops  of 
Calega  officinalis  (Goat's  Rue).  Used  as  Galactagogue  and 
Nerve  Stimulant.  Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

Fluidextract  Qambir  Compound.     See  Fluid  Gambir  Com- 
pound. 

Fluidextract    Qelsemium,    Squibb      pint,         ;  %  pint. 

Fluid exlractum  Celsemii;  Fluidextract  Yellow  Jasmine.  From 
dried  rhizome  and  roots  of  Gelsemium  sempervirens.  Assays 
0.3  Gm.  alkaloids  in  100  mils  (Cc.).  Antineuralgic,  Nerve 
Sedative,  Antispasmodic.  Average  Dose:  1/o  minim  (0.03  mil). 
Antidotes:  tannin;  emetics;  atropine  or  strophanthin  subcu- 
taneously;  stimulants. 

Fluidextract   Gentian,   Squibb  pint,         ;%pini. 

Fluid extraclum    Ccnliance.      From  dried    rhizome   and    roots   of 

Ccntiana  lutea.  Simple  Bitter.  Average  Dose:  15  minims 
(1  mil  [Cc.]). 


SQUIBB'S  MATERIA  MEDICA        103 

Fluidextract  Gentian  Compound,  Squibb 

pint,          ;  J/2  pint,          ;  '/4  pint> 

A  concentrated  form  of  the  official  compound  tincture  gentian, 
being  made  from  the  same  ingredients  and  with  same  menstruum. 
It  represents  the  official  ingredients  in  the  proportion  of  1  Gm. 
of  the  compound  powder  in  each  mil  (Cc.).  Dose:  10  to  20 
minims  (0.65  to  1 .25  mils) . 

FLUIDEXTRACT.  GERANIUM. 

Fluidextractum  Ceranii,  N.  F.;  Fluidextract  Cranesbill.  From 
dried  rhizome  of  Geranium  maculalum.  External  and  Intes- 
tinal Astringent.  Average  Dose:  15  minims  (1  mil  [Cc.]). 
Applied  externally  pure. 

Fluidextract.  Ginger,  Squibb  pint,         ;    %   pint, 

Fluidexlractum  Zingiberis.  From  best  Jamaica  Ginger,  the 
dried  rhizome  of  Zingiber  officinale.  Aromatic,  Carminative, 
Gastro-intestinal  Stimulant.  Average  Dose:  15  minims  (1  mil 
[Cc.]). 

Fluidextract   Ginger,    Soluble.   See  Fluid  Ginger  for  Syrup. 

0  Fluidextract  Glycyrrhiza   (Licorice),  Squibb 

pint,          ;   '/4  pint, 

Extractum  Glycyrrhizce  Fluidum,  U.  S.  P.  1890.  Considered 
superior  to  present  official  product.  From  dried  rhizome  and 
roots  of  C/pcprr/iiza  glabra  lypica  or  of  C.  glabra  glandulifera, 
known  in  commerce  respectively  as  Spanish  Licorice  and 
Russian  Licorice.  Demulcent,  Expectorant.  Average  Dose :  30 
minims  (2  mils  [Cc.]).  Incompatible  with  acids. 

FLUIDEXTRACT  GOAT'S  RUE.     See  Fluidextract  Galega. 
Fluidextract  Golden  Seal.       See  Fluidextract  Hydrastis. 
FLUIDEXTRACT  GOLD  THREAD.     See  Fluidextract  Coptis. 
Fluidextract    Gossypium.         See  Fluidextract  Cotton  Root. 

FLUIDEXTRACT  GRANATUM.     See  Fluidextract  Pomegranate. 

• 

Fluidextract  Grindelia,  Squibb        pint,         ;    Y^   pint> 

FluiJexlractum  Grindelia.  From  dried  leaves  and  flowering 
tops  of  Grindelia  camporum,  G,  cunei folia  or  G.  squarrosa. 
Antispasmodic,  Antiratarrhal ;  in  asthma,  whooping-cough, 
etc.  Average  Dose:  30  minims  (2  mils  [Cc.]). 


The  Squibb  products  are  recognized  everywhere  as  the  Quality 
Standard.  They  are  of  uniform  purity  and  strength,  hence 
therapeutically  dependable.  When  ordering  or  prescribing  med- 
icinal products,  you  will  do  well  always  to  specify  SQUIBB'S. 


104        SQUIBB'S  MATERIA  MEDICA 

Fluidextract  Grindelia  Soluble,   Squibb 

pint,         ;    '/^   pin'' 

The  resinous  matter  has  been  rendered  soluble  by  treatment  with 
alkali,  the  finished  fluidextract  being  miscible  without  precipita- 
tion with  aqueous  preparations,  as  syrups,  elixirs,  etc.  Incom- 
patible with  acids  or  acid  salts.  Same  action  and  dose  as 
preceding. 

Fluidextract  Guarana,  Squibb          pint,         ;    J4   pint, 

Fluidexlractum  Cuaranae.  Assays  3.6  to  4.4  Gm.  caffeine  in 
100  mils  (Cc.).  Nerve  Stimulant,  Analgesic;  chiefly  in  head- 
aches and  narcotic  poisoning.  Average  Dose :  30  minims  (2 
mils). 

Fluidextract  Hamamelis  Leaves,  Squibb 

pint,          ;  1/4  pint, 

Fluidexlraclum  Hamamelidis  Foliorum,  N.  F.;  Fluidextract 
Witch  Hazel.  Astringent.  Average  Dose:  30  minims  (2  mils 
[Cc.]). 

FLUIDEXTRACT  HELIANTHEMUM. 

FluiJextractum  Helianthemi,  N.  F.;  Fluidextract  Frost-Weed. 
Astringent,  Alterative,  Emetic.  Average  Dose:  1  fluidrachm 
(4  mils  [Cc.]). 

FLUIDEXTRACT  HELLEBORE.      See  Fluidextract  Veratrum  Viride. 

FLUIDEXTRACT   HELONIAS. 

Fluidexiraci  Heloniadis,  N.  F.;  Fluidextract  False  Unicorn. 
From  dried  rhizome  and  roots  of  Chamalirium  luleum.  As- 
serted Uterine  Tonic.  Average  Dose:  30  minims  (2  mils 
[Cc.]). 

Fluidextract   Hemlock   Seed.      See   Fluidextract  Conium. 
FLUIDEXTRACT   HEMP,   CANADIAN.     See    Fluidextract   Apocynum. 
Fluidextract  Henbane.     See  Fluidextract  Hyoscyamus. 

FLUIDEXTRACT  HOPS. 

Fluid extraclum  Humuli,  N.  F.  From  dried  strobiles  of  Humulus 
Lupulus.  Aromatic  Bitter,  Stomachic.  Average  Dose:  30 
minims  (2  mils  [Cc.]). 

FLUIDEXTRACT     HORSE-NETTLE      BERRIES.       See      Fluidextract 
Solanum. 

FLUIDEXTRACT  HYDRANGEA. 

Fluidextraclum  Hydrangea,  N.  F.  From  dried  rhizome  and 
roots  of  Hydrangea  arborescent.  Cathartic,  Diuretic,  Diaphor- 
etic. Average  Dose:  30  minims  (2  mils  [Cc.]). 


SQUIBB'S  MATERIA  MEDICA        105 

®  Fluidextract   Hydrastis,  Squibb     pint,         ;  |4  P"11- 
Fluidextractum  Hydrastis;   Fluidextract   Golden  Seal.     Assays 
1.8    to    2.2.  Gm.    ether-soluble    alkaloids    in    100    mils    (Cc.). 
Hemostatic     Astringent,    Cholagogue,    Antihydrotic.      Average 
Dose:  30  minims  (2  mils  [Cc.]). 

FLUIDEXTRACT    HYDRASTIS,   AQUEOUS.     See   Glycerite   Hydrastis. 

Fluidextract*  Hydrastis,  Colorless,     so-called.      See    Fluid 
Golden  Seal  Colorless. 

FLUIDEXTRACT      HYDRASTIS      NON-ALCOHOLIC.    See      Glycerite 
Hydrastis. 

Fluidextract  Hyoscyamus,  Squibb  pint,  ;  %  pint, 
FluiJexlraclum  Hyoscyami;  Fluidextract  Henbane.  From  dried 
leaves  and  flowering  tops  of  Hyoscyamus  niger.  Assays  0.053 
to  0.075  alkaloids  in  100  mils  (Cc.).  Antispasmodic 
Sedative,  Analgesic;  in  coughs,  nervous  ailments,  pains,  etc. 
Average  Dose:  3  minims  (0.2  mil).  Antidotes:  tannin,  emetics; 
morphine,  pilocarpine,  physostigmine,  aconitine;  stimulants  by 
mouth.  This  fluidextract  frequently  deposits  crystals  of  potas- 
sium nitrate,  a  salt  always  found  in  good  hyoscyamus  leaves. 
It  is  not  a  necessary  element  in  the  therapeutic  efficiency  of 
the  preparation,  and  when  found  may  be  removed  by  decanta- 
tion,  or  by  filtration. 

®  Fluidextract  Ipecac,  Squibb          pint,         ;    %   pint, 

Fluidextractum  Ipecacuanha.  Assays  1.8  to  2.2  Gm.  ether- 
soluble  alkaloids  in  100  mils  (Cc.).  Nauseant  Expectorant, 
Emetic,  and  Antamebic.  Average  Dose :  Emetic,  i  5  minims 
(1  mil);  Expectorant,  1  minim  (0.06  mil). 

FLUIDEXTRACT  IRIS.     See  Fluidextract  Blue   Flag. 
Fluidextract    Jaborandi.      See  Fluidextract   Pilocarpus. 

FLUIDEXTRACT  JALAP. 

Fluidextractum  Jalaps,  N.  F.  From  dried  tuberous  root  of 
Exogonium  Pur§a.  Hydragogue  Cathartic.  Average  Dose : 
15  minims  (1  mil  [Cc.]). 

Fluidextract  Jamaica  Dogwood,  Squibb 

pint,          ;    14    pint, 

From  root-bark  of  Piscidia  Erylhrina.  Hypnotic,  Sedative,  and 
dental  Anodyne;  in  nervous  insomnia,  ovarian  pain,  toothache, 
etc.  Dose:  1  to  2  fluidrachms  (4  to  8  mils  [Cc.]). 


Since  we  make  only  one  quality  of  each  product,  that  best 
suited  to  the  purposes  intended,  the  specification  "Squibb's" 
is  not  open  to  various  interpretations,  but  has  a  plain,  positive 
meaning.  When  ordering  or  prescribing,  specify  SQUIBB'S. 


106       SQUIBB'S  MATERIA  MEDICA 

FLUIDEXTRACT  JUGLANS. 

Fluidextractum  Juglandis,  N.  F.;  Fluidextract  Butternut.  From 
inner  bark  of  root  of  Juglans  cinerea.  Obsolescent  Cathartic, 
similar  to  cascara.  Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

Fluidextract  Juniper,  Squibb          pint,        ;   !4   pint, 
Fluid extraclum  Juniperi,  N.  F.     From  dried  ripe  fruit  (berries) 
of    Juniperus     communls.     Irritant    Diuretic.     Average     Dose: 
1    fluidrachm   (4  mils   [Cc.]). 

FLUIDEXTRACT  KAVA. 

Fluidextractum  Kav<e,  N.  F.  From  dried  rhizome  and  roots 
of  Piper  melhysticum.  Mild  Irritant,  similar  to  cubeb;  used 
chiefly  in  gonorrhea.  Average  Dose:  15  minims  (1  mil 
[Cc.]). 

Fluidextract  Kola,  Squibb  pint,         ;  %  pint, 

Fluidextractum  Kolas,  N.  F.  From  dried  cotyledons  of  several 
species  of  Cola.  Nerve  and  Muscle  Stimulant,  Diuretic. 
Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

Fluidextract  Krameria,  Squibb  pint,  ;  ]/4  pint, 
Fluidexiraclum  Krameria,  N.  F.;  Fluidextract  Rhatany. 
Dropped  from  U.  S.  P.  From  dried  root  of  Krameria  Iriandra, 
K.  Ixina  or  K.  argentea.  Powerful  Astringent;  chiefly  in  in- 
testinal catarrh  and  hemorrhage.  Average  Dose :  1 5  minims 
(1  mil  [Cc.]). 

Fluidextract  Ladies'  Slipper.     See  Fluidextract  Cypripedium. 

Fluidextract    Lappa,    Squibb  pint,         ;  ]/£  pint, 

Fluidexlractum  Lappte,  N.  F.;  Fluidextract  Burdock.  From 
dried  root  of  Arctium  Lappa.  Alterative.  Average  Dose:  30 
minims  (2  mils  [Cc.]). 

Fluidextract   Larkspur,  Squibb  pint,         ;  |4  pint, 

Acetic  Fluidextract  Larkspur.  The  use  of  Larkspur,  Stavesacre 
and  other  varieties  of  Delphinium  in  ointments,  lotions,  etc., 
for  the  removal  of  body-parasites,  has  created  a  demand  for 
a  concentrated  form  which  may  be  diluted  with  water  and  alco- 
hol at  the  time  of  using.  A  fluidextract  made  with  10  percent, 
acetic  acid  is  best  adapted  for  this  purpose,  as  it  contains  all 
the  virtues  of  the  drug.  To  prepare  parasiticidal  lotion,  take: 
Fluidextract  Larkspur  Squibb,  I  fl.  oz. ;  gradually  add  alcohol 
1%  fl.  ozs.;  set  aside  5  minutes,  then  add  water  14%  fl.  ozs. 
Let  stand  24  hours,  then  filter.  Little  used  internally  (dropsy, 
asthma,  etc.).  Dose:  3  minims  (0.2  mil  [Cc.]).  Antidotes: 
tannin,  emetics;  ammonia  or  digitalis;  brandy. 

FLUIDEXTRACT  LEPTANDRA. 

Fluidexiraclum  Leplandra ;  Fluidextract  Culver's  Root.  From 
dried  rhizome  and  roots  of  Veronica  virginica.  Cathartic. 
Average  Dose:  15  minims  (I  mil  [Cc.]). 


SQUIBB'S  MATERIA  MEDICA        107 

Fluidextract   Licorice.     See   Fluidextract  Glycyrrhiza. 

Fluidextract  Licorice  for  Quinine  Mixtures.      See  Fluid 
Glycyrrhiza. 

FLUIDEXTRACT  LIFE  ROOT.     See  Fluidextract  Senecio. 

FLUIDEXTRACT  LILY  OF  THE  VALLEY  FLOWERS.    See  Fluidextract 
Convallaria   Flowers. 

FLUIDEXTRACT   LILY   OF   THE    VALLEY    ROOT.     See    Fluidextract 
Convallaria  Root. 

Fluidextract  Lobelia,  Squibb  pint,         ;  |4  P>n*. 

Fluidextraclum  Lobelice.  The  new  U.  S.  P.  has  readopted  the 
alcoholic  fluidextract  and  dropped  the  acetic  product  of  VHIth. 
Rev.  From  dried  leaves  and  flowering  tops  of  Lobelia  inflata. 
Antispasmodic,  Expectorant;  in  whooping-cough,  asthma, 
etc.  Average  Dose:  2'/2  minims  (0.15  mil  [Cc.]).  Anti- 
dotes: tannin,  emetics  hypodermically ;  brandy  or  ammonia; 
morphine. 

FLUIDEXTRACT  LUPULIN. 

Fluid ex tractum  Lupulini,  N.  F.  From  glandular  trichomes  sep- 
arated from  strobiles  of  Humulus  Lupulus.  Bitter  Tonic,  simi- 
lar to  gentian.  Average  Dose:  8  minims  (0.5  mil  [Cc.]). 

Fluidextract    Mandrake.       See    Fluidextract    Podophyllum. 
FLUIDEXTRACT  MARIGOLD.     See  Fluidextract  Calendula. 

FLUIDEXTRACT  MATICO. 

FluiJextraclum  Matico,  N.  F.  From  leaves  of  Piper  angusli- 
folium.  Used  as  Genito-urinary  Stimulant  and  Anticatarrhal; 
similar  to  buchu,  cubeb,  etc.,  Average  Dose :  1  fluidrachm 
(4  mils  [Cc.]). 

FLUIDEXTRACT  MEZEREUM. 

Fluid exlraclum  Mezerei,  N.  F.  Dropped  from  U.  S.  P.  From 
dried  bark  of  Daphne  Mezereum,  D.  Gnidium  or  D.  Laureola. 
Used  as  Antiluetic  and  Vesicant.  Dose :  5  to  1 5  minims  (0.2 
to  1  mil  [Cc.]),  well  diluted.  Antidotes:  demulcents;  emetics. 

FLUIDEXTRACT  MULLEIN  LEAVES. 

Fluidexiractum  Verbasci  Foliorum,  N.  F.  From  dried  leaves 
of  Verbascum  Thapsus  and  other  species  of  Verbascum. 
Demulcent,  Anticatarrhal.  Average  Dose :  I  fluidrachm  (4 
mils  [Cc.]). 


The  founder  of  the  House  of  Squibb,  Dr.  Edward  R.  Squibb, 
not  only  had  high  ideals,  but  lived  and  labored  for  them;  and, 
in  the  words  of  William  Miller  Bartlett,  "the  House  of  Squibb 
stands  today  as  a  living  monument  to  the  honor,  integrity,  zeal 
and  devotion  of  its  founder." 


108       SQUIBB'S  MATERIA  MEDICA 

Fluidextract  Nux  Vomica,  Squibb  pint,  ;  1/4  pint, 
Fluid extractum  Nucis  Vomicat.  From  dried  ripe  seeds  of 
Strychnos  Nux-vomica.  Assays  2.37  to  2.63  Gm.  alkaloids  in 
100  mils  (Cc.).  Bitter  Stomachic,  Tonic.  Average  Dose:  1 
minim  (0.06  mil).  Antidotes:  tannin;  apomorphine  subcutane- 
ously  as  emetic;  chloral  hydrate  with  bromides  per  rectum; 
chloroform  by  inhalation  if  required. 

FLUIDEXTRACT  ORANGE  PEEL,  BITTER. 

Fluidexlractum  Auranlli  Amari.  From  dried  rind  of  fruit  of 
Citrus  Aurantium  amara.  Aromatic  Bitter  Stomachic,  taste 
corrigent.  Average  Dose:  15  minims  (1  mil  [Cc.]). 

Fluidextract  Orange  Peel,  Sweet,  Squibb 

pint,          ;    |/4   pint, 

From  dried  outer  rind  of  ripe  fruit  of  Citrus  Auranlium. 
Flavoring  ingredient. 

FLUIDEXTRACT  PARACOTO. 

Fluid extractum  Paracolo,  N.  F.  From  bark  of  an  unidentified 
tree  belonging  to  Lauracea.  Intestinal  Astringent.  Average 
Dose:  5  minims  (0.3  mil  [Cc.]). 

FLUIDEXTRACT  PAREIRA. 

Fluidextraclum  Pareirce,  N.  F.  From  dried  root  of  Chondo- 
dendron  tomentosum.  Bitter  Tonic.  Average  Dose:  30  min- 
ims (2  mils  [Cc.]). 

FLUIDEXTRACT  PARSLEY  ROOT. 

Fluidextractum  Peiroselini  RaJicis,  N.  F.  Carminative.  Aver- 
age Dose:  30  minims  (2  mils  [Cc.]). 

Fluidextract   Passion   Flower,   Squibb 

pint,  ;    '/4   pint, 

From    dried    leaves    of    Passiflora    irtcarnata.  Used    as    Nerve 

Sedative,  in  insomnia,  restlessness,  etc.  Dose :  1 5  to  30  minims 
(I  to  2  mils  [Cc.]). 

Fluidextract  Phytolacca,  Squibb.        pint,         ;  !4  pint, 

Fluidextraclum  Phytolacca,  N.  F.;  Fluidextract  Poke  Root. 
From  dried  root  of  Phytolacca  decandra.  Used  as  Emetic, 
Alterative,  Cathartic.  Average  Dose:  emetic,  15  minims  (1  mil 
[Cc.]);  alterative  1J/2  minims  (0.1  mil). 

Fluidextract  Pichi,  Squibb  pint,         ;  %  pint, 

From  dried  leaflets  and  twigs  of  Fabiana  imbricala.  Diuretic, 
Urinary  Anticatarrhal.  Considered  contra-indicated  in  or- 
ganic renal  disease.  Dose :  30  to  60  minims  (2  to  4  mils 
[Cc.]). 


SQUIBB'S  MATERIA  MEDICA        109 

Fluidextract  Pilocarpus,  Squibb  pint,  ;  %  pint, 
Fluid extraclum  Pilocarpi;  Fluidextract  Jaborandi.  From  dried 
leaflets  of  Pilocarpus  Jaborandi  or  of  P.  microphyllus.  Assays 
0.55  to  0.65  Gm.  alkaloids  in  100  mils  (Cc.).  Sialagogue, 
Galactagogue,  Diaphoretic;  also  used  as  stimulant  of  hair  folli- 
cles. Average  Dose:  30  minims  (2  mils). 

FLUIDEXTRACT  PINK  ROOT.    See  Fluidextract  Spigelia. 
FLUIDEXTRACT  PIPSISSEWA.     See  Fluidextract  Chimaphila. 
Fluidextract    Pleurisy    Root.      See  Fluidextract  Asclepias. 

Fluidextract  Podophyllum,  Squibb     pint,        ;  !4  pint, 

FluiJextractum  PoJophylli;  Fluidextract  Mandrake  (May 
Apple).  From  dried  rhizome  of  Podophyllum  peltatum. 
Cathartic.  Average  Dose:  8  minims  (0.5  mil  [Cc.]). 

Fluidextract  Poke  Root.     See  Fluidextract  Phytolacca. 

FLUIDEXTRACT  POMEGRANATE. 

Fluidextraclum  Granaii.  From  dried  bark  of  stems  and  roots 
of  Punica  Cranatum,  and  containing  about  10  percent,  glycerin. 
Anthelmintic,  Astringent.  Average  Dose:  30  minims  (2  mils 
[Cc.]). 

FLUIDEXTRACT  PRICKLY  ASH  BARK.     See  Fluidextract  Xanthoxy- 
lum. 

Fluidextract  Prunus  Virginiana.        See  Fluidextract  Wild 
Cherry. 

Fluidextract  Quassia,  Squibb  pint,         ;    %   pint, 

Fluid exlractum  Quassia,  N.  F.  Dropped  from  U.  S.  P.  From 
wood  of  Picrasma  excelsa  or  Quassia  amara.  Bitter  Tonic, 
Teniafuge.  Average  Dose:  8  minims  (0.5  mil  [Cc.]). 

Fluidextract    Quebracho.     See    Fluidextract   Aspidosperma. 
Fluidextract  Queens  Root.       See   Fluidextract  Stillingia. 

FLUIDEXTRACT  QUERCUS. 

Fluidexlractum  Quercus,  N.  F.;  Fluidextract  White  Oak.  From 
dried  bark  of  Quercus  alba;  10  volume  percent,  glycerin. 
Tannin-bearing  Astringent  like  krameria.  Average  Dose :  1 5 
minims  (1  mil  [Cc.]). 

Fluidextract  Red   Clover.        See  Fluidextract  Trifolium. 


The  Squibb  Ideals  have  taken  concrete  form  in  the  Squibb 
Products;  these  are  universally  recognized  as  standards  of 
uniform  Purity  and  Efficacy,  that  is,  general  Excellence  and 
Reliability.  Specify  SQUIBB'S  when  prescribing  or  ordering. 


110       SQUIBB'S  MATERIA  MEDICA 

FLUIDEXTRACT  RHAMNUS  CATHARTICA. 

Fluideictractum  Rhamni  Calharticte,  N.  F.;  Fluidextract  Buck- 
thorn Berries.  From  dried,  ripe  fruit  of  Rhamnus  cathartica. 
Cathartic.  Average  Dose:  15  minims  (1  mil  [Cc.]). 

Fluidextract   Rhamnus   Frangula.      See  Fluidextract  Fran- 
gula. 

Fluidextract  Rhamnus  Purshiana.       See  Fluidextract  Cas- 
cara  Sagrada. 

Fluidextract   Rhatany.     See  Fluidextract  Krameria. 
Fluidextract  Rhubarb,  Squibb         pint,        ;    %  pint, 

Fluidextraclum  Rhei.  From  prime  quality  Chinese  root.  Stom- 
achic, Laxative.  Average  Dose:  15  minims  (1  mil  [Cc.]). 

FLUIDEXTRACT  RHUS  GLABRA. 

Fluidextraclum  Rhols  Glabrce,  N.  F.;  Fluidextract  Sumach 
Berries.  From  dried  fruit  of  Rhus  glabra,  and  containing  10 
volume  percent,  of  glycerin.  Tannin-bearing  Astringent,  sim- 
ilar to  krameria.  Average  Dose:  15  minims  (I  mil  [Cc.]). 

FLUIDEXTRACT  ROSE. 

Fluidexiractum  Rosa.  From  dried  petals  of  Rosa  gallica,  and 
containing  10  percent,  by  volume  of  glycerin.  Mild  Astringent; 
used  chiefly  as  flavoring  and  for  making  syrup  rose.  Average 
Dose:  30  minims  (2  mils  [Cc.]). 

FLUIDEXTRACT  RUBUS. 

Fluidexlractum  Rubi,  N.  F.;  Fluidextract  Blackberry.  Dropped 
from  U.  S.  P.  From  dried  bark  of  Rubus  villosus,  R.  nigro- 
baccus  or  of  R.  cuneifolius.  Intestinal  Astringent.  Average 
Dose:  15  minims  (1  mil  [Cc.]). 

Fluidextract  Rumex,  Squibb  pint,         ;  %  pint, 

Fluidexiractum  Rumicis,  N.  F.;  Fluidextract  Yellow  Dock. 
From  dried  root  of  Rumex  crispus.  Alterative,  External  As- 
tringent. Average  Dose:  1  fluidrachm  (4  mils  [Cc.]).  Ex- 
ternally pure  (in  ulcers  and  skin  diseases). 

Fluidextract  Sabal,  Squibb  pint,         ;  %  pint, 

Fluidexiractum  Sabal;  Fluidextract  Saw  Palmetto.  From  par- 
tially dried  berries  of  5erenoa  serrulata.  Used  as  Genito- 
urinary Anticatarrhal.  Average  Dose:  15  minims  (1  mil 
[Cc.]). 

FLUIDEXTRACT  SANGUINARIA. 

Fluidextractum  Sanguinariae,  N.  F.;  Fluidextract  Bloodroot. 
Essentially  the  alcoholic  product  of  U.  S.  P.  1890;  not  acetic, 
as  per  U.  S.  P.  Vlllth  Rev.  From  dried  rhizome  of  San- 
guinaria  canadensis.  Expectorant;  large  doses  are  emetic. 
Average  Dose:  IJ/2  minims  (O.I  mil  [Cc.]). 


SQUIBB'S  MATERIA  MEDICA        lit 

Fluidextract  Sarsaparilla,  Squibb       pint,         ;  j/4  pint, 
Fluidextraclum   Sarsaparilla.     From      best      grade      of      official 
Sarsaparilla.     Used  as  Alterative;   in  chronic  rheumatism,  skin 
diseases,  etc.     Average  Dose:  30  minims  (2  mils   [Cc.]). 

Fluidextract  Sarsaparilla  Compound,  Squibb 

pint,          ;    ]/4  pint, 

Fluid extractum  Sarsaparilla  Composilum.  Each  mil  (Cc.} 
representing  1  Gm.  mixture  of  sarsaparilla,  licorice,  sassafras 
and  mezereum,  and  carrying  10  volume  percent,  of  glycerin. 
Average  Dose:  30  minims  (2  mils). 

Fluidextract  Sarsaparilla  Compound  for  Syrup,  Squibb 

pint,          ;    ]/4   pint, 

For  conveniently  making  Syrup  Sarsaparilla  Compound,  take  of 
this  fluidextract  7  fl.  ozs.  and  enough  syrup  to  make  30  fl.  ozs. 

Fluidextract  Saw  Palmetto.       See  Fluidextract  Sabal. 

FLUIDEXTRACT  SCOPARIUS. 

Fluidexlractum  Scoparii,  N.  F.;  Fluidextract  Broom  Tops. 
From  dried  tops  of  Cyiisus  Scoparius.  Diuretic.  Considered 
contra-indicated  in  the  presence  of  acute  renal  inflammation. 
Average  Dose:  15  minims  (1  mil  [Cc.]). 

FLUIDEXTRACT  SCULLCAP.     See  Fluidextract  Scutellaria. 

FLUIDEXTRACT  SCUTELLARIA. 

Fluidextracium  Scutellaria,  N.  F.;  Fluidextract  Scullcap. 
From  dried  plant  of  Scutellaria  lateriflora.  Used  as  Nervine  and 
Antispasmodic,  chiefly  in  chorea  and  convulsions.  Average 
Dose:  15  minims  (1  mil  [Cc.]). 

FLUIDEXTRACT  SENECIO. 

Fluidextraclum  Senecionis,  N.  F.;  Fluidextract  Life  Root. 
From  dried  overground  portions  of  Senecio  aureus.  Used  as 
Tonic,  Diuretic  and  Diaphoretic.  Average  Dose :  1  fluidrachm 
(4  mils  [Cc.]). 

Fluidextract   Senega,  Squibb  pint,         ;  %  pint, 

Fluidexlractum  Senega;  Fluidextract  Seneka  Snakeroot. 
Pharmacists  and  physicians  frequently  complain  that  this  fluid- 
extract  becomes  "worthless"  or  "spoiled"  by  gelatinizing.  Good 
senega  root  contains  a  large  amount  of  pectin,  and  the  better 
the  root  the  more  it  appears  to  contain.  This  physical  property 
is  necessary  to  its  proper  therapeutic  effects,  and  therefore  it 
would  not  be  justifiable  to  select  a  root  which  is  inferior  in  this 
property.  Unless  the  gelatinized  clot  is  of  too  long  standing, 
warmth  applied,  or  at  times  a  few  drops  of  ammonia  water 
with  agitation,  will  restore  it  to  its  original  fluid  condition. 
Nauseant  Expectorant.  Average  Dose  :  15  minims  (1  mil  [Cc.]). 

The  Squibb  Label  on  a  package  is  a  positive*guaranty  for  the 
uniform  Purity  and  Reliability  of  the  product.  We  make  only 
ONE  quality:  the  SQUIBB  quality;  and  our  prices  are  as  low 
as  they  can  be  made  for  that  quality.  Specify  SQUIBB'S. 


112        SQUIBB'S  MATERIA  MEDICA 

0  Fluidextract  Senna,  Squibb  pint,        ;  14  pint, 

Fluidexiractum  Sennas.  From  best  quality  senna  leaves,  the 
dried  leaflets  of  Cassia  acutifolia  or  of  C.  angusiifolia,  known 
in  commerce  respectively  as  Alexandria  Senna  and  India 
Senna.  Cathartic.  Average  Dose:  30  minims  (2  mils  [Cc.]). 

FLUIDEXTRACT  SERPENTARIA. 

Fluidextractum  Serpentarice,  N.  F.;  Fluidextract  Virginia 
Snakeroot.  From  dried  rhizome  and  roots  of  Aristolochia  Ser- 
pentaria  or  of  A.  reticulala.  Bitter,  like  gentian.  Average 
Dose:  15  minims  (1  mil  [Cc.]). 

FLUIDEXTRACT  SOLANUM. 

Fluidextractum  Solani,  N.  F.;  Fluidextract  Horse-Nettle 
Berries.  From  air-dried  ripe  fruit  of  Solanum  carolinense. 
Used  as  Antispasmodic  and  Sedative;  in  convulsions,  epilepsy, 
etc.  Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

FLUIDEXTRACT  SPIGELIA. 

Fluidextractum  Spigeliae;  Fluidextract  Pink  Root.  From  dried 
rhizome  and  roots  of  Spigelia  marilandica,  Teniafuge.  Average 
Dose:  1  fluidrachm  (4  mils  [Cc.]). 

FLUIDEXTRACT  SPIKENARD.     See  Fluidextract  Aralia. 

Fluidextract  Squill,  Squibb  pint,         ;  I  4  pint, 

Fluidextracium  Scillce.  From  bulb  of  white  variety  of  Urginea 
maritime.  The  new  U.  S.  P.  has  dropped  the  acetic  fluid- 
extract  official  in  VHIth  Rev.,  and  adopted  the  alcoholic  prep- 
aration. Physiologically  assayed  according  to  U.  S.  P.  and 
standardized;  minimum  lethal  dose  not  greater  than  0.0006  mil 
(Cc.)  per  Gm.  weight  of  frog.  Expectorant,  Diuretic;  large 
doses  are  Emetic.  Average  Dose:  1J/2  minims  (O.I  mil). 

Fluidextract    Squill    Compound,    Squibb 

pint,          ;   ]/4  pint, 

For  Syrup.  Each  mil  (Cc.)  represents  1  Gm.  mixture  of  equal 
parts  each  squill  and  senega,  and  0.0125  Gm.  tartar  emetic. 
160  mils  with  840  mils  syrup  makes  1000  mils  syrup  squill 
compound. 

FLUIDEXTRACT  STAPHISAGRIA. 

Fluidextractum  Staphisagrite ;  Fluidextract  Stavesacre.  From 
ripe  seed  of  Delphinium  Staphisagria.  Antiparasitic,  Rube- 
facient;  in  scabies,  rheumatism,  etc.  Applied  in  1:16  dilution. 
Antidotes:  tannin,  emetics;  chloral  hydrate;  chloroform  by  in- 
halation; ammonia,  digitalis,  brandy. 

Fluidextract    Star   Grass.     See   Fluidextract  Aletris. 
FLUIDEXTRACT    STAVESACRE.      See    Fluidextract    Staphisigria. 


SQUIBB'S  MATERIA  MEDICA        113 

Fluidextract  Stillingia,  Squibb  pint,         ;  |4  pint, 

Fluidexlractum  Stillingiai ;  Fluidextract  Queen's  Root.  From 
dried  root  of  Stillingia  sylvatica.  Sialagogue,  Expectorant, 
Alterative.  Average  Dose:  30  minims  (2  mils  [Cc.]). 

Fluidextract  Stillingia  Compound,  Squibb 

pint,          ;  }/4  pint, 

Fluidextractum  Stillingia  Composiium,  N.  F.  Each  mil  (Cc.) 
represents  1  Gm..  mixture  of  Stillingia,  corydalis,  iris,  sambucus, 
chimaphila,  coriander  and  xanthoxylum  berries.  Used  as 
Alterative;  in  liver  diseases,  spring  fever,  etc.  Average  Dose: 
30  minims  (2  mils  [Cc.]). 

FLUIDEXTRACT  STRAMONIUM. 

Fluid extractum  Slramonii,  N.  F.  From  leaves  of  Datura 
Stramonium  or  of  D.  Tatula.  Assays  0.22  to  0.28  Gm.  alka- 
loids in  100  mils  (Cc.).  Antispasmodic,  Sedative,  Analgesic. 
Average  Dose:  I  minim  (0.06  mil  [Cc.]).  Antidotes:  tannin; 
apomorphine  hypodermically  as  emetic;  morphine;  ammonia  by 
inhalation. 

FLUIDEXTRACT  SUMACH  BERRIES.     See  Fluidextract  Rhus  Glabra. 

Fluidextract  Sumbul,  Squibb  pint,         ;  %  pint, 

Fluidexlracium  Sumbul;  Fluidextract  Musk  Root.  From  dried 
rhizome  and  roots  of  Ferula  Sumbul.  Used  as  Antispasmodic, 
Nerve  Tonic.  Average  Dose:  30  minims  (2  mils  [Cc.]). 

FLUIDEXTRACT   SUNDEW.     See   Fluidextract   Drosera. 

Fiuidextract   Taraxacum,   Squibb       pint,         ;  %  pint, 

Fluidextractum  Taraxaci;  Fluidextract  Dandelion.  From  dried 
root  of  Taraxacum  officinale.  Bitter  Tonic,  mild  Laxative. 
Average  Dose:  2J/2  fluidrachms  (10  mils  [Cc.]). 

FLUIDEXTRACT  THUJA. 

Fluidextractum  Thuja,  N.  F.;  Fluidextract  Arbor  Vitae.  From 
recently  dried,  leafy  young  twigs  of  Thuja  occidentalis.  Used 
as  Febrifuge,  Expectorant,  Anthelmintic.  Average  Dose:  30 
minims  (2  mils  [Cc.]). 

FLUIDEXTRACT  THYME. 

Fluidexlractum  Thyrni,  N.  F.  From  dried  tops  of  Thymus 
vu/gan's.  Antispasmodic,  Carminative,  Aromatic  Stimulant. 
Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 


This  house  supplies  only  one  quality  of  each  product:  that  best 
suited  to  the  purposes  intended.  The  specification  "Squibb's" 
is  not  open  to  various  interpretations;  it  has  a  plain,  posi- 
tive meaning.  Therefore,  when  prescribing,  specify  SQUIBB'S. 


114        SQUIBB'S  MATERIA  MEDICA 

Fluidextract  Trifolium,  Squibb  pint,         ;  |4  pint, 

Fluidextractum  Trifolii,  N.  F.;  Fluidextract  Red  Clover. 
From  dried  flowers  of  Trifolium  pratense.  Used  as  Alterative, 
Expectorant.  Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 
Generally  administered  in  combination  with  other  drugs. 

Fluidextract  Trifolium  Compound,  Squibb 

pint,          ;  '/$  pint, 

Each  mil  (Cc.)  represents  1  Gm.  of  mixture  of  8  parts  red 
clover  blossoms  and  4  parts  each  of  berberis,  poke  root,  bur- 
dock root,  cascara,  stillingia,  and  prickly  ash  bark.  Used  as 
Alterative.  Dose :  1  to  2  fluidrachms  (4  to  8  mils  [Cc.]).  To 
prepare  Syrup  Trifolium  Compound,  take  of  this  Fluidextract 
4  fluidounces,  Potassium  Iodide  128  grains,  and  Simple  Syrup 
12  fluidounces. 

Fluidextract  Trillium,   Squibb  pint,         ;  |4pint, 

Fluidextract  Trillii,  N.  F.;  Fluidextract  Beth  Root.  From 
dried  rhizome  of  Trillium  ereclum.  Used  as  Tonic,  Astringent. 
Average  Dose:  30  minims  (2  mils  [Cc.]). 

Fluidextract  Triticum,  Squibb  pint,         ;  14  pint, 

FluiJextractum  Trilici;  Fluidextract  Couch  Grass  or  Dog 
Grass.  From  dried  rhizome  of  Agropyron  repens.  Diuretic, 
Demulcent;  in  cystitis  and  irritable  bladder.  Average  Dose: 
2/2  fluidrachms  (10  mils  [Cc.]). 

FLUIDEXTRACT  TURKEY  CORN.     See  Fluidextract  Corydalis. 

Fluidextract   Uva   Ursi,  Squibb  pint,         ;  %  pint, 

Fluidextraclum  Uva  Ursi;  Fluidextract  Bearberry  Leaves. 
From  leaves  of  Arctostaphylos  U\>a-ursi;  30  percent,  by  vol- 
ume of  glycerin.  Diuretic,  Urinary  Anticatarrhal;  chiefly  in 
vesical  catarrh.  Average  Dose:  30  minims  (2  mils  [Cc.]). 

Fluidextract  Valerian,  Squibb  pint,         ;  %  pint, 

Fluidextractum  Valeriance,  N.  F.  From  root  of  Valtriana 
officmalis.  Used  in  hysteria  and  other  nervous  excitations. 
Average  Dose:  30  minims  (2  mils  [Cc.]). 

Fluidextract    Veratrum    Viride,    Squibb 

pint,  ;  '/4  pint, 

Fluidexiractum    Veralri    Viridis.      From    rhizome    and    ror 
V 'eralrum  "viride.      Cardiac   Depressant,   Diaphoretic;    em 
in  acute  febrile  affections,  puerperal  convulsions,  etc.      ^ 
Dose:    1J/2   minims    (0.1    mil    [Cc.]).     Antidotes:    tannin,   apo- 
morphine   subcutaneously    as   emetic;    then    morphine   with   atro- 
pine ;   stimulants. 

FLUIDEXTRACT  VERBASCUM.     See   Fluidextract   Mullein  Leaves. 


SQUIBB'S  MATERIA  MEDICA        115 

FLUIDEXTRACT  VERVAIN. 

Fluidextraclum  Verbena,  N.  F.;  Fluidextract  Blue  Vervain. 
From  dried  overground  portion  of  Verbena  haslala.  Tonic, 
Expectorant,  Diaphoretic.  Average  Dose:  15  minims  (1  mil 
[Cc.]). 

Fluidextract  Viburnum  Opulus.  Squibb 

pint,          ;   ]/4  pint, 

Fluidexlraclum  Viburni  Opuli,  N.  F.;  Fluidextract  Cramp 
Bark.  From  dried  bark  of  Viburnum  opulus  (Fam.  Capn- 
foliacete).  Used  as  Antispasmodic  and  Uterine  Sedative. 
Average  Dose:  30  minims  (2  mils  [Cc.]). 

Fluidextract  Viburnum  Prunifolium,  Squibb 

pint,          ;  ]/4  pint, 

Fluid extra'ctum  Viburni  Prurtifolii ;  Fluidextract  Black  Haw 
From  dried  bark  of  root  of  Viburnum  prunifolium  or  of  V. 
Lentago.  Used  as  Uterine  Sedative;  chiefly  in  dysmenorrhea, 
habitual  abortion,  etc.  Average  Dose:  30  minims  (2  mils  [Cc.]). 

FLUIDEXTRACT  WAHOO.     See  Fluidextract  Euonymus. 
FLUIDEXTRACT  WHITE  OAK.     See  Fluidextract  Quercus. 

Fluidextract  White  Pine  Compound.          See  Fluid  White 
Pine  Compound. 

Fluidextract  Wild  Cherry,  Squibb  pint,  ;  %  pint, 
Fluidextractum  Pruni  Virginians,  N.  F.  Dropped  from 
U.  S.  P.  From  bark  of  Prunus  serolina  (P.  virginiana).  Con- 
tains 20  volume  percent,  of  glycerin.  Sedative,  Expectorant, 
but  mainly  used  as  flavor.  Average  Dose:  30  minims  (2  mils 
[Cc.]). 

Fluidextract  Wild  Cherry  for  Syrup.        See  Fluid  Wild 
Cherry. 

FLUIDEXTRACT  WILD  INDIGO.     See  Fluidextract  Baptisia. 
Fluidextract   Wild   Yam.     See  Fluidextract  Dioscorea. 

Fluidextract     Witch     Hazel     Leaves.        See    Fluidextract 
Hamamelis. 

FLUIDEXTRACT  XANTHOXYLUM. 

Fluidexlraclum  Xanthoxyli;  Fluidextract  Prickly  Ash  Bark. 
Fronv  Xanthoxylum  americanum  or  X.  ClaVa-Herculis.  Bit- 
ter, similar  to  gentian.  Average  Dose:  30  minims  (2  mils 
[Cc.]). 


The  prices  of  the  Squibb  Products  are  in  all  instances  as  low  as 
the  quality  and  quantity  of  ingredients  and  the  expense  of  man- 
ufacture allow.  They  inchjde  containers,  packing  and  boxing.  When 
ordering  or  prescribing  medicinal  products,  specify  SQUIBB'S. 


116       SQUIBB'S  MATERIA  MEDICA 

Fluidextract  Yellow  Dock.    See  Fluidextract  JRumex. 
Fluidextract  Yellow  Jasmine.     See  Fluidextract  Gelsemium. 
Fluidextract  Yerba  Santa.     See  Fluidextract  Eriodictyon. 

Fluidextract   Yerba  Santa  Aromatic.     See  Fluid  Eriodic- 
tyon   Aromatic. 

Fluidextract  Zea,  Squibb  pint,         ;  J4  P'nt> 

Fluidextractum  Zees,  N.  F.;  Fluidextract  Corn  Silk.  From 
fresh  styles  and  stigmas  of  Zea  Mays.  Used  as  Diuretic  and 
Anticatarrhal,  in  inflammatory  conditions  of  bladder.  Average 
Dose:  I  Buidrachm  (4  mils  [Cc.]). 

FLUIDGLYCERATES. 

A  new  class  of  N.  F.  preparations,  of  same  drug  strength  a* 
fluidextracts  (Cc.  for  Gm.),  but  containing  about  50  percent,  by 
volume  of  glycerin  and  no  alcohol.  The  following  are  official: 

Fluidglycerate  Cascara  Sagrada,  Squibb 

pint,  ;  5/4  pint, 

Fluidglycerate  Cascara  Sagrada  Aromatic,  Squibb 

pint  ;  J/4  pint, 

Fluidglycerate     Glycyrrhiza  (Licorice),  Squibb 

pint,          ;  J/4  pint, 

Fluidglycerate  Krameria,  Squibb       pint,         ;  %  pint, 

Fluidglycerate    Rhubarb,    Squibb       pint,         ;  %  pint, 

FORMALIN  AND  FORMOL.     Brands  of  Solution  Formaldehyde. 

FORMIN.     Brand  of  Hexamethylenamine. 

FORMYL  TRIBROMIDE.    See  Bromoform. 

Formyl  Trichloride.         See  Chloroform. 

Formyl   Triiodide.         See  lodoform. 

Fowler's  Solution.        See  Solution   Potassium  Arsenite. 

Foxglove.        See    Digitalis. 

FRANCIS'     TRIPLEX     PILLS.       See     Pills     Aloes,     Mercury     and 
Scammony  Compound. 

FRANGULA. 

Frangula ;  Buckthorn  Bark.  Dried  bark  of  Rhamnus  Fran- 
gula  (Fam.  Rhamnaccai).  Laxative,  similar  to  cascara. 
Average  Dose:  15  grains  (1  Gm,).  (See  also  Fluidextract.) 


SQUIBB'S  MATERIA  MEDICA        117 

Friars'   Balsam.        See  Tincture  Benzoin  Compound. 
FRINGE  TREE  BARK.     See  Chionanthus. 
FROST-WEED.    See  Helianthemum. 
Fucus. 

Fucus,  N.  F.;  Bladderwrack.  Dried  thallus  of  Fucus  Vesicu- 
losus  (Fam.  Fucaceai).  Alterative,  Resolvent;  in  goiter,  tuber- 
culous glands,  etc.  Average  Dose:  10  grains  (0.65  Gm.). 

GALANGA. 

Galangal,  N.  F.  Dried  rhizome  of  Alpinia  officinarum  (Fam. 
Zingiberacete) .  Aromatic  odor;  hot,  ginger-like  taste.  Aro- 
matic Carminative,  resembling  ginger.  Average  Dose:  15  grains 
(1  Gm.). 

GALEGA. 

Calega,  N.  F. ;  Goat's  Rue.  Dried  flowering  tops  of  Galeqa 
officinalis  (Fam.  Leguminoscs) .  Indistinct  odor;  mucilaginous, 
slightly  bitter,  astringent  taste.  Used  as  Galactagogue,  Nerve 
Stimulant.  Average  Dose:  1  drachm  (4  Gm.). 

GALLS.     See   Nutgall. 

GAMBIR. 

Cambir;  Pale  Catechu.  Dried  extract  prepared  from  decoc- 
tions of  leaves  and  twigs  of  Ourouparia  Cambir  (Fam.  Rub- 
iacea).  Soluble  in  water  to  extent  of  65  percent.,  in  alcohol  60 
percent.  Odorless,  brown  powder;  bitterish,  very  astringent 
taste.  Intestinal  Astringent.  Average  Dose:  15  grains  (1 
Gm.).  (See  also  Tincture.) 

GAMBOGE. 

Cambogia.  Gum-resin  obtained  from  Carclnia  Hanburii  (Fam. 
Guttiferce).  Not  less  than  65  percent,  soluble  in  alcohol.  In- 
odorous, very  acrid,  cylindrical  pieces;  grayish-orange-brown 
externally,  orange-red  internally.  The  powder  is  bright-yellow 
and  irritating  to  nasal  mucous  membrane.  Hydragogue  Cathar- 
tic. Average  Dose:  2  grains  (0.13  Gm.). 

GARANTOSE.     Brand  of  Benzosulphinide   (Saccharin). 

GARGLE  GUAIAC  COMPOUND. 

Gargarisma  Guaiaci  Composilum,  N.  F.  Each  100  mils  (Cc.) 
contains  10  mils  each  ammoniated  tincture  guaiac  and  com- 
pound tincture  cinchona,  20  mils  clarified  honey,  4  Gm.  potas- 
sium chlorate,  0.2  mil  oil  peppermint. 


If  difficulty  is  experienced  in  procuring  any  Squibb  product 
in  the  original  packages  here  listed,  please  notify  us;  we 
Shall  see  that  your  wants  are  met  promptly  and  satisfactorily. 


118        SQUIBB'S  MATERIA  MEDICA 

GARLIC. 

Allium,  N.  F.  Fresh  bulb  of  Allium  sativum  (Fam.  Liliaceet). 
irritant  Expectorant,  similar  to  senega.  Average  Dose:  30 
grains  (2  Gm.). 

®  GELATIN. 

Celatinum.  From  animal  tissues  (skin,  ligaments  and  bones) 
by  treatment  with  boiling  water.  Insoluble  in  cold  water  (but 
swells  and  softens  when  immersed  in  it),  alcohol,  chloroform, 
ether,  oils;  soluble  in  hot  water,  acetic  acid,  glycerin.  Coagu- 
lated by  tannin,  chlorine,  bromine  and  corrosive  mercury 
chloride;  formaldehyde  renders  it  hard  and  insoluble.  Nutri- 
ent, but  used  largely  pharmaceutically. 

GELATIN  CHONDRUS. 

Celatinum  Chondri,  N.  F.;  Irish  Moss  Gelatin.  Evaporated, 
scaled  decoction  of  Irish  Moss.  Demulcent,  Nutritive. 

GELATIN  GLYCERINATED. 

Gelatinum  Glycsrinatum.  50  percent,  gelatin.  Base  for  throat 
lozenges  and  medicated  suppositories  and  bougies. 

GELSEMIUM. 

Celsemium;  Yellow  Jasmine  Root.  Dried  rhizome  and  roots 
of  Celsemium  sempervirens  (Fam.  Loganiacea")  .  Pronounced 
characteristic  odor;  slightly  aromatic,  bitter  taste.  Antineuralgic, 
Antispasmodic,  Nerve  Sedative;  in  migraine  and  neuralgia, 
in  ovarian,  uterine  and  rheumatic  pain.  Average  Dose:  J/2 
grain  (0.03  Gm.).  (See  also  Fluidextract;  Tincture.) 

®  Gentian,   Squibb        Ground   for  Percolation       tin,  Ib. 

Cenliana;  Gentian  Root.  Dried  rhizome  and  roots  of  Cen- 
iiana  lutea  (Fam.  Gentianaceae).  Simple  Bitter,  Stomachic. 
Average  Dose:  15  grains  (1  Gm).  (See  also  Elixir;  Extract; 
Fluidextract;  Tincture.) 


Gentian  Compound   Ground,  Squibb  tin,  Ib. 

Mixture  of  ground  Gentian,  Bitter  Orange  Peel  and  Carda- 
mom, in  proportions  given  in  U.  S.  P.  formula  for  Tincture 
Gentian  Compound,  and  used  for  preparing  latter. 

GERANIUM. 

Geranium,  N.  F.;  Cranesbill.  Dried  rhizome  of  Geranium 
maculatum,  collected  in  late  summer  or  autumn.  Intestinal 
Astringent,  like  krameria.  Average  Dose:  15  grains  (1  Gra.). 


SQUIBB'S  MATERIA  MEDICA        119 

0  Ginger,  Squibb 

*  Ground  for  Percolation  tin,  Ib. 

Powdered  tin,  Ib. 

sprinkler-top  tins,  4-oz.,  per  doz. 

2-oz.,  per  doz.         ;  1  -oz.,  per  doz. 

Zingiber,  Dried  rhizome  of  Zingiber  officlnale  (Fam. 
Zingberaceee),  The  chief  sources  of  ginger  are  West  Indies, 
Jamaica,  Africa,  Hindoostan  and  China.  The  rhizome  is 
collected  in  the  winter,  cleaned,  scalded  and  rapidly  dried,  and 
is  then  known  as  Black  Ginger.  The  process  of  preparation  is 
carried  still  further  with  Jamaica  Ginger  and  some  that  comes 
from  the  East  Indies,  by  the  removal  of  this  dark  skin,  thus 
leaving  the  roots  yellowish-white  in  color.  As  this  variety 
commands  a  higher  price,  the  poorer  qualities  are  sometimes 
made  to  resemble  it  by  bleaching  or  covering  with  thin  milk  of 
lime  or  slaked  lime.  It  has  a  warming,  cordial  effect  when 
used  as  a  condiment,  and  also  tends  to  prevent  flatulence.  The 
article  here  offered  is  strictly  pure  and  of  best  quality  procur- 
able Average  Dose:  15  grains  (1  Cm.).  (See  also  Fluid 
Ginger;  Fluidextract;  Oleoresin;  Tincture.) 

Ginger  Soluble,  for  Syrup.     See  Fluid  Ginger  for  Syrup. 

Glauber's  Salt.        See  Sodium  Sulphate. 

GLUCOSE  LIQUID. 

Clucosum.  From  incomplete  hydrolysis  of  starch;  consists 
chiefly  of  dextrose  and  dextrins.  Nearly  colorless,  odorless, 
thick,  sweet  liquid.  Very  soluble  in  water,  sparingly  in  alco- 
hol. Nutrient,  but  used  largely  pharmaceutically  and  techni- 
cally. 

GLUSIDE.     See    Benzosulphinide    (Saccharin). 

GLUSIMIDE.     Brand  of  Benzosulphinide    (Saccharin). 

@  Glycerin,   Squibb  bottle,  Ib.         ;  |4  Ib. 

C/pcen'num;  Glycerol.  CsH5(OH)3.  A  liquid  obtained  by 
hydrolysis  of  vegetable  or  animal  fats,  or  fixed  oils.  Most  care- 
fully selected  and  subjected  in  our  laboratories  to  the  severest 
tests  for  purity.  It  is  of  proper  density,  stands  the  rigid  sul- 
phuric acid  test,  and  is  free  from  arsenic,  mineral  impurities  and 
acidic  radicles  indicative  of  contaminating  salts.  An  especially 
acceptable  article  for  internal  use.  Clear,  thick,  sweet  liquid. 
Sp.  gr.  not  below  1 .249.  Soluble  in  all  proportions  of  water  or 
alcohol;  insoluble  in  ether,  chloroform  or  oils.  Used  chiefly 
technically  and  as  a  solvent,  but  also  internally  in  place  of  sugar 
in  diabetes  and  as  nutritive.  Average  Dose:  1  fluidrachm  (4 
mils  [Cc.]).  Incompatible  with  chromic  acid  and  permanga- 
nates. (See  also  Suppositories.) 

The  Squibb  products  are  recognized  everywhere  as  the  Quality 
Standard.  They  are  of  uniform  purity  and  strength,  hence 
theraupeutically  dependable.  When  ordering  or  prescribing  medi- 
cinal products,  you  will  do  well  always  to  specify  SQUIBB'S. 


120       SQUIBB'S  MATERIA  MEDICA 

GLYCERITE  ACID  CARBOLIC.    See  Glycerite  PhenpL 

0G!ycerite  Acid   Tannic,   Squibb 

bottle,  pint         ;  J4  P'n* 

G/pcen'/um  Acid'i  Tannici  20  percent,  tannic  acid.  Antiseptic* 
Astringent  paint,  on  fissured  nipples,  erysipelas,  sores,  etc.; 
rarely  internally.  Average  Dose:  30  minims  (2  mils  [Cc.]). 

Glycerite  Bismuth,  Squibb          bottle,  pint         ;  %  pint 

Glyceritiim  Bismuthi,  N.  F.  1  fluidrachm  contains  about  16 
grains  bismuth  and  sodium  tartrate;  100  mils  (Cc.)  yield  about 
12.8  Gm.  bismuth  oxide.  Gastric  Sedative,  Intestinal  Astrin- 
gent; used  mainly  for  making  elixirs.  Ordinary  Dose:  10  min- 
ims (0.65  mil  [Cc.]). 

©  Glycerite  Boroglycerin,  Squibb 

bottle,   Ib.         ;    14    Ib. 

Glyceritum  Boroglycerini  U.  S.  P.  is  apt  to  become  discolored 
during  the  process  of  making.  We  therefore  increase  the 
boric  acid  from  31  percent,  to  35  percent,  (equivalent  to  56  per- 
cent, glyceryl  borate  or  boroglycerin)  and  obtain  a  whiter  and 
better  article.  Thick,  sweet,  colorless  liquid.  Soluble  in  water. 
Antiseptic. 

GLYCERITE  EGG  YOLK. 

Clyceritum  Vilelli,  N.  F.;  Glyconin.  45  percent,  egg  yolk,  55 
percent,  glycerin.  Protective,  Emulsifier,  Vehicle. 

GLYCERITE  GOLDEN  SEAL.     See  Glycerite   Hydrastis. 

GLYCERITE  GUAIAC. 

Clyceritum  Cuaiaci,  N.  F.  Each  fluidounce  contains  about  40 
grains  guaiac,  with  30  minims  solution  potassium  hydroxide.  Al- 
terative, Emmenagogue.  Average  Dose :  30  minims  (2  mils 
[Cc.]).  Incompatible  with  mineral  acids,  ferric  chloride,  spirit 
nitrous  ether. 

GLYCERITE  HYDRASTIS. 

Glycerilum  HyJrastis;  so-called  Fluidextract  Hydrastis  Non- 
Alcoholic.  Assays  from  1.12  to  1.37  Gm.  ether-soluble  alka- 
loids in  100  mils  (Cc.).  An  alcoholic  percolate  is  made  from 
powdered  hydrastis,  the  alcohol  removed  by  distillation,  and 
resultant  thick  extract  incorporated  with  water  and  glycerin. 
Astringent,  Antiphlogistic;  topically  and  internally.  Average 
Dose:  30  minims  (2  mils  [Cc.]). 

Glycerite  Pepsin,  Squibb  bottle,  pint         ;  %  pint 

Glycerilum  Pepsini,  N.  F.;  Glycerol  Pepsin.  Each  fluidounce 
contains  about  40  grains  of  1  :3000  pepsin  and  5  minims  hydro- 
chloric acid.  Useful  in  making  essence  pepsin  and  where 
pepsin  is  desired  in  liquid  form.  Average  Dose:  45  minims 
(3  mils  [Cc.]). 


SQUIBB'S  MATERIA  MEDICA        121 

GLYCERITE  PHENOL. 

Clyceritum  Phenolis ;  Glycerite  Carbolic  Acid.  Mixture  of  1 
volume  liquefied  phenol  and  4  volumes  glycerin.  External  and 
internal  Antiseptic,  Antipruritic.  Average  Dose:  5  minims  (0.3 
mil  [Cc.]),  in  water.  Applied  diluted  with  water,  1  :4  to  6. 

GLYCERITE  STARCH. 

Clyceritum  Amyli.  !0  percent,  starch  well  gelatinized.  Vehicle 
for  dermics;  pill-excipient,  etc. 

GLYCERITE  TAR. 

Clyceritum  Picis  Liquids,  N.  F.  100  mils  (Cc.)  contain  6.3 
Gm.  tar,  'with  glycerin,  alcohol  and  water.  Expectorant,  Anti- 
septic. Average  Dose:  1  flutdrachm  (4  mils  [Cc.]). 

GLYCERITE  TRAGACANTH. 

Clyceritum  Tragacanthas,  N.  F.  100  mils  (Cc.)  contain  about 
12.5  Gm.  tragacanth,  with  glycerin  and  water.  Pill  excipient. 

GLYCEROGELATINS. 

Soft  masses,  melting  at  body  temperature,  composed  of  gela- 
tin, glycerin,  water  and  a  medicament  employed  in  skin  dis- 
eases, with  or  without  the  addition  of  zinc  oxide.  They  are 
prepared  with  glycerinated  gelatin  (U.  S.  P.)  as  vehicle.  The 
N.  F.  recognizes:  Glycerogelaiin  Salicylic  Acid,  10%;  C/p- 
cerogelatin  lodoform,  10%;  Clycerogelalin  Zinc  Firm.,  10% 
zinc  oxide;  Glycerogelatin  Zinc  Soft,  10%  zinc  oxide. 


Glycerol.         See  Glycerin  and  Glycerite. 
GLYCONIN.    See  Glycerite  Egg  Yolk. 

GLYCOPHENO  AND  GLYCOSINE.     Brands  of  Benzosulphinide  (Sac- 
charin). 

0  Qlycyrrhiza  Powdered,  Squibb 

Clycyrrhiza.  Licorice.  Dried  rhizome  and  roots  of 
G/ycprr/iiza  glabra  glandulifera  or  of  C.  glabra  lypica  (Fam. 
Leguminosffl) ;  known  in  commerce  respectively  as  Russian 
Licorice  and  Spanish  Licorice.  Demulcent,  Expectorant;  also 
absorbent  in  pill  making.  Average  Dose:  30  grains  (2  Gm.). 
(See  also  Extract;  Fluidextract;  Mixture;  Powder;  Troches 
[Part  II].) 


Since  we   make   only  one   quality  of  each   product,   that   best 
suited  to   the   purposes   intended,  the   specification      Squibb  s 
is  not   open  to  various  interpretations,  but  has  a  plain,  positive 
meaning.      When    ordering    or    prescribing,    specify    SQUIBB'S. 


122        SQUIBB'S  MATERIA  MEDICA 

GLYCYRRHIZIN  AMMONIATED. 

Clycyrrhizinum  Ammonialum.  Sweet  principle  of  glycyrrhiza 
(licorice  root).  Dark-brown  or  brownish-red,  odorless,  swe«t 
scales.  Freely  soluble  in  water;  soluble  in  alcohol.  Taste 
corrigent;  Expectorant  and  Demulcent,  in  pectoral  affections. 
Average  Dose:  4  grains  (0.25  Gm.).  Incompatible  with  min- 
eral acids. 

GODFREY'S  CORDIAL.     See  Mixture  Opium  and  Sassafras. 

Gold   Chloride,   Squibb  15-grain  vial, 

AuHCl4.4H;>O.  Reddish-brown,  very  deliquescent  crystals; 
approx.  49  percent,  gold.  Soluble  in  water,  alcohol,  ether. 
Used  medicinally  as  Alterative,  mainly  in  dipsomania  and  tuber- 
culosis. Used  largely  in  photography.  Dose:  I/QQ  to  Vis  grain 
(0.001  to  0.004  Gm.)  Keep  well  protected  against  air  and 
light. 

Gold  and  Sodium  Chloride,  Squibb 

J/g-oz.  vial,          ;  15-gr.  vial, 

Ann  el  Sodii  ChlorlJum.  Mixture  of  equal  parts  anhydrous 
gold  chloride  and  sodium  chloride,  containing  30  percent,  gold. 
Orange-yellow,  deliquescent,  odorless  powder;  saline,  metallic 
taste.  Soluble  freely  in  water,  partially  in  alcohol.  Average 
Dose:  */i2  grain  (0.005  Gm.),  in  pills  or  tablets.  Keep  well 
stoppered,  in  dry  place.  (See  also  Tablets  .[Part  IIJ-) 

GOLD  THREAD.     See  Coptis. 

GOLDEN   SEAL.     See   Hydrastis. 

GOULARD'S  CERATE.     See   Cerate  Lead  Subacetate. 

Granular  Effervescent  Salts,  Squibb 
Grouped  for  convenience  of  reference. 

Skilfully  made  products,  from  purest  ingredients,  in  accurate 
and  proper  proportions  to  secure  the  best  results.  They  .dis- 
solve rapidly  with  brisk  effervescence.  For  descriptions  see  re- 
spective titles. 

Antilithic.     See  Sodium  Phosphate  Compound. 

Carlsbad   Artificial  bottle,  lb.  4  oz.,  per  doz. 


Kissingen   Artificial  bottle,  lb. 

Lithium  Citrate  bottle,  lb. 

Magnesium  Citrate  bottle,  lb. 

Magnesium  Sulphate  bottle,  lb. 

Sodium    Phosphate  bottle,  lb. 
Sodium  Phosphate  Compound 

Sodium  Sulphate  bottle,  lb. 

Vichy  Artificial  bottle,  lb. 


4  oz.,  per  doz. 
4  oz.,  per  doz. 
4  oz.,  per  cioz. 
4  oz.,  per^doz. 
4  oz.,  per  doz. 
4  oz.,  per  doz. 
4  oz.,  per  doz. 
4  oz.,  per  doz. 


SQUIBB'S  MATERIA  MEDICA        123 


Crindelia;  Gum-plant.  Dried  leaves  and  flowering  tops  of 
Crindelta  camporum  or  G.  cuneifolia  or  G.  squarrosa  (Fam. 
Composites).  Balsamic  odor;  aromatic,  bitter,  resinous  taste. 
Antispasmodic,  Anticatarrhal.  Average  Dose:  30  grains  (2 
Gm.).  (See  also  Fluidextract.) 

GRIFFITH'S  MIXTURE.    See  Mixture  Iron  Compound. 
GRIFFITH'S  PILLS.     See  Pills  Iron  Carbonate. 

Guaiac  Resin,  Squibb 

Whole  tin,  Ib. 

*  Ground  for  Percolation  tin,  Ib. 

Cuaiacum  ;  Guaiac.  Resin  of  wood  of  Cuaiacum  officinale  or 
of  C.  sanctum  (Fam.  Zygophyllacea)  .  Irregular,  greenish-gray, 
brown  masses  or  grayish  powder,  of  balsamic  odor  and  slightly 
acrid  taste.  Used  as  Alterative  and  Emmenagogue.  Average 
Dose:  15  grains  (1  Gm.).  (See  also  Tincture.) 

GUAIAC  WOOD. 

Cuaiaci  Lignum,  N.  P.;  Lignum  Vitae.  Heartwood  of  Cuaiacum 
officinale  or  of  C.  sanctum  (Fam.  Zygophyllacece).  Used  as 
Alterative,  Emmenagogue.  Average  Dose:  60  grains  (4  Gm.) 

©  GUAIACOL. 

Cuaiacol;  Methylpyrocatechin.  Monomethyl  ether  of  ortho- 
dihydroxybenzene,  obtained  from*wood-tar  creosote  or  prepared 
synthetically.  C7HgO2.  Colorless,  crystalline  solid;  or 
colorless  to  yellowish,  oily  liquid  of  aromatic  odor,  sp.  gr. 
1.110  to  1.114.  1  Gm.  dissolves  in  53  mils  (Cc.)  water;  6.8 
mil  glycerin;  miscible  with  alcohol,  ether,  chloroform.  Anti- 
tubercular,  Intestinal  Antiseptic;  topical  Antipyretic.  Aver- 
age Dose  :  (of  liquid  form)  :  8  minims  (0.5  mil)  ;  topically,  1  5  to 
30  minims  (1  to  2  mils)  with  same  quantity  olive  oil  or 
glycerin.  (See  also  Tablets  [Part  II].). 

GUAIACOL  BENZOATE.     See  Benzosol. 

0  Guaiacol  Carbonate,  Squibb  bottle,  oz. 

Cuaiacolis  Carbonas.  (C7H-O)oCC>3.  White,  nearly  odor- 
less and  tasteless  powder.  1  Gm.  dissolves  in  60  mils  (Cc.) 
alcohol,  I  chloroform,  18  ether;  slightly  soluble  in  glycerin;  in- 
soluble in  water.  Antitubercular,  Intestinal  Disinfectant.  Aver= 
age  Dose:  15  grains  (1  Gm.).  (See  also  Tablets  [Part  II].) 


The  founder  of  the  House  of  Squibb,  Dr.  Edward  R.  Squibb, 
not  only  had  high  ideals,  but  lived  and  labored  for  them;  and, 
in  the  words  of  William  Miller  Bartlett,  "the  House  of  Squibb 
stands  today  as  a  living  monument  to  the  honor,  integrity,  zeal 
and  devotion  of  its  founder." 


124        SQUIBB'S  MATERIA  MEDICA 

GUARANA. 

Cuarana.  A  dried  paste  consisting  chiefly  of  crushed  seeds  of 
Paullinia  Cupana  (Fam.  Saplndaced),  a  Brazilian  plant.  Yields 
not  less  than  4  percent,  caffeine.  Reddish-brown,  coarse  pow- 
der; slight  odor;  taste  astringent,  smoky,  bitter,  then»  sweetish. 
Nerve  Stimulant,  Analgesic,  Tonic.  Average  Dose :  30  grains 
(2  Gm.).  (See  also  Fluidextract.) 

Guaranine.          See  Caffeine. 

GUM  ARABIC.     See  Acacia. 

GUM  BENJAMIN  or  GUM  BENZOIN.    See  Benzoin. 

GUTTA  PERCHA. 

Cutta  Percha,  N.  F.  Purified,  coagulated,  milky  exudate  of 
various  trees  of  genus  Palaquium  (Fam.  5apo<ace<z).  Insolu- 
ble in  water;  90  percent,  soluble  in  chloroform,  benzin,  oil 
turpentine. 

GUY'S  PILLS.     See   Pills  Digitalis.   Squill  and   Mercury. 
Ha  la/ one.     See  Tablets,  Part  II  of  this  book. 

HAMAMELIS  LEAVES. 

HamameliJis  Folia,  N.  F.  Ground  dried  leaves  of  Hamamelis 
virgimana  (Fam.  H amameUdacece) .  Tannin-bearing  Astringent. 
Average  Dose:  30  grains  (2  Gm.).  (See  also  Fluidextract.) 

HEDONAL. 

Methylpropylcarbinolurethane.  White  powder,  of  faint  aro- 
matic odor  and  taste.  Soluble  readily  in  alcohol,  ether,  chloro- 
form; slightly  soluble  in  water.  Hypnotic.  Dose:  15  to  30 
grains  (1  to  2  Gm.). 

HELIANTHEMUM. 

Helianthemum,  N.  F.;  Frost-weed.  Dried  herb  of  Helianthe- 
mum  canadense  (Fam.  Cistacece).  Aromatic  odor;  astringent, 
bitter  taste.  Obsolescent  Astringent,  Alterative.  Average  Dose : 
I  drachm  (4  Gm.). 

Hellebore,  American  or  Green.     See  Veratrum  Viride. 

HELMITOL. 

Hexamethylenamine  Methylenecitrate.  White  powder;  acidu- 
lous taste.  Soluble  in  10  parts  water;  almost  insoluble  in  alco- 
hol or  ether.  Urinary  Disinfectant  and  Acidifier.  Dose:  10 
to  15  grains  (0.65  to  1  Gm.). 

HELONIAS. 

Helonias,  N.  F.;  False  Unicorn.  Dried  rhizome  and  roots 
of  Chamielirium  luieum  (Fam.  Liliaceat).  Distinctive  odor; 
bitter,  astringent  taste.  Bitter  Tonic;  ingredient  of  "female" 
remedies.  Average  Dose:  30  grains  (2  Gm.). 


SQUIBB'S  MATERIA  MEDICA        125 

HEMATOXYLON. 

H cemaloxylon,  N.  F. ;  Logwood.  Heart-wood  of  Haimatoxy- 
lon  campechianum  (Fam.  Leguminosa) .  Reddish-brown 
chips;  faint,  agreeable  odor;  sweetish,  astringent  taste.  Intes- 
tinal Astringent;  Coloring.  Colors  urine  and  stools  red.  Dose: 
30  to  60  grains  (2  to  4  Gm.). 

Hemoglobin,  Squibb  bottle,  Ib.         ;  %  Ib.         ;  oz. 

Iron-bearing  constituent  of  blood,  prepared  from  fresh  ox-blood 
by  removal  of  serum  and  careful  purification  and  drying  at  low 
temperature.  Brownish-red  powder;  about  0.4  percent,  iron. 
Soluble  in  water.  Dose:  10  to  30  grains.  (0.65  to  2  Gm.). 

HEMLOCK.     See  Conium. 

HEMP  CANADIAN.     See  Apocynum. 

Henbane.     See   Hyoscyamus. 

"j"  HEROIN.     Brand  of  Diacetylmorphine. 

0  Hexamethylenamine,  Squibb 

carton,  Ib.          ;  ]/£  Ib.         ;  oz. 

Hexamelhylenamina;  Hexamethylene-tetramine;  Ammonio- 
formaldehyde.  C^H^N-i.  Condensation  product  of  ammonia 
and  formaldehyde.  Colorless,  almost  odorless  crystals  or  pow- 
der. Decomposed  in  acid  media,  formaldehyde  being  liberated.  1 
Gm.  dissolves  in  1.5  mils  (Cc.)  water;  12.5  alcohol;  320  ether; 
soluble  also  in  chloroform.  Useful  Urinary  Antiseptic;  in 
acid  cystitis,  typhoid  bacilluria,  etc.  Average  Dose :  4  grains 
(0.25  Gm.),  well  diluted,  or  as  tablets  with  a  copious  draught 
of  water.  Often  prescribed  in  conjunction  with  acid  sodium 
phosphate,  where  urine  is  alkaline;  given  two  hours  after  the 
phosphate.  Incompatible  with  acids,  acid  salts,  ammonium  salts, 
tannin  and  mercuric  chloride.  This  chemical  is  also  known 
by  various  trade  names  (Cystogen,  Formin,  Uritone,  Urotropin, 
Hexamine,  Aminoform,  etc.).  (See  also  Tablets  [Part  II].). 

HIERA  PICRA.     See  Powder  Aloes  and  Canella. 
Hoffmann's  Anodyne.         See  Spirit  Ether  Compound. 

HOLOCAINE  HYDROCHLORIDE. 

CisH^o^Oo.HCI.  Salt  of  phenetidyl-acetphenetidin.  Small, 
colorless,  odorless,  faintly  bitter  crystals.  Soluble  in  50  parts 
water,  freely  in  alcohol.  Local  Anesthetic,  in  1  percent,  solu- 
tion. 


The  Squibb  Ideals  have  taken  concrete  form  in  the  Squibb 
Products;  these  are  universally  recognized  as  standards  of 
uniform  Purity  and  Efficacy,  that  is,  general  Excellence  and 
Reliability.  Specify  SQUIBB'S  when  prescribing  or  ordering. 


126        SQUIBB'S  MATERIA  MEDICA 

©  HOMATROPINE    HYDROBROMIDE. 

Homatropince  Hydrobromidum.  Ci6H2iO3N.HBr.  White, 
odorless,  bitter,  crystalline  powder  or  small  prisms.  1  Gm.  dis- 
solves in  6  mils  (Cc.)  water,  40  alcohol,  420  chloroform;  in- 
soluble in  ether.  Mydrialic  (1  percent,  solution),  Antihydrotic 
and  Sedative,  like  atropine.  Average  Dose:  !/120  grain  (0.0005 
Gm.).  Antidotes:  tannin,  then  emetics;  gastric  lavage;  mor- 
phine, pilocarpine,  physostigmine,  etc. 

HONEY. 

Mel.  Saccharine  secretion  deposited  in  honey-comb  by  the  bee, 
Apis  mellifera  (Fam.  Apids).  Nutrient,  but  used  largely 
pharmaceutically. 

HONEY  BORAX.     See  Honey  Sodium  Borate. 

HONEY  CLARIFIED. 

Mel  Depuralum.  Honey  purified  by  heating  with  paper  pulp, 
removing  scum,  straining  and  adding  5  percent,  glycerin.  Used 
pharmaceutically. 

HONEY  ROSE. 

Mel  Ros<£.  100  Gm.  contain  12  mils  (Cc.)  fluidextract  rose 
in  clarified  honey.  Pleasant  astringent  addition  lo  mouth  washes 
and  gargles  for  inflamed  or  ulcerated  mouth  and  throat. 

HONEY  ROSE,  WITH  BORAX. 

Mel  Rosce  et  Sodii  Boralis,  N.  F.  10  percent,  borax,  5 
glycerin,  85  rose  honey.  Antiseptic,  Astringent  Collutory, 
especially  for  children. 

HONEY  SODIUM  BORATE. 

Mel  Sodii  Boratls,  N.  F.;  Honey  of  Borax.  10  percent, 
sodium  borate,  5  glycerin,  85  clarified  honey.  Antiseptic  Col- 
lutory. 

HOPE'S  MIXTURE.       See  Mixture  Camphor  Acid. 

HOPS. 

Humulus.  Dried  strobiles  of  Humulus  Lupulus  (Fam.  Moro- 
cco?), bearing  their  glandular  trichomes.  Strong,  valerian-like 
odor;  aromatic,  bitter  taste.  Aromatic  Bitter  Stomachic. 
Average  Dose:  30  grains  (2  Gm.). 

HORSE-NETTLE  BERRIES.     See  Solanum. 

Household  Products,  Squibb 

A  line  of  pure  products  especially  in  demand  for  use  in  the 
household.  The  list  comprises: 

Baking  Powder;  Benzoinated  Cold  Cream;  Borax  Powdered 
(Sodium  Borate);  Castor  Oil;  Castor  Oil  Aromatized;  Cod 
Liver  Oil;  Cold  Cream;  Cream  of  Tartar  (Potassium  Bitar- 
trate) ;  Epsom  Salt  (Magnesium  Sulphate) ;  Extract  Vanilla 
(Tincture  Vanilla) ;  Flexible  Collodion  (Liquid  Court 
Plaster);  Fluid  Cascara  Aromatic  (Non-  Alcoholic) ;  Glycerin; 
Magnesia  Magma  (Milk  of  Magnesia);  Milk  Sugar; 


SQUIBB'S  MATERIA  MEDICA        127 

Household  Products,  Squibb  (Cont.) 

Olive  Oil;  Rochelle  Salt  (Potassium  and  Sodium  Tar- 
trate);  Sodium  Bicarbonate;  Sodium  Phosphate;  Soft  Soap; 
Solution  Acid  Carbolic  Crude;  Solution  Hydrogen  Peroxide; 
Spices;  Talcum  Powder;  Tarragon  Vinegar.  For  sale 
by  druggisls  only;  grocers  do  not  have  them.  For  descrip- 
tions see  respective  titles. 

HYDRANGEA. 

Hydrangea,  N.  F.;  Seven-barks.  Dried  rhizome  and  roots  of 
Hydrangea  arborescens  (Fam.  Saxifragacets) .  Inodorous; 
taste  sweetish,  becoming  slightly  acrid.  Cathartic,  Diuretic, 
Diaphoretic.  Average  Dose:  30  grains  (2  Gm.). 

Hydrastine,  Squibb  15-gr.  vial, 

Hydrasiina.  CojHoiOeN.  While  alkaloid  from  Hydrasfis 
canadensis,  or  prepared  synthetically.  White  or  creamy-white 
crystals  or  powder.  1  Gm.  is  soluble  in  1 70  mils  (Cc.)  alcohol, 
1.4  chloroform,  175  ether;  almost  insoluble  in  water.  Alterative, 
Bitter  Tonic,  Uterine  Hemostatic.  Average  Dose:  !/6  grain 
(0.01  Gm.),  as  pills  or  tablets.  [Not  to  be  confounded  with 
the  eclectic  resinoid  "Hydrastin,"  a  brown  powder,  vastly  weak- 
er than  hydrastine  alkaloid.] 

Hydrastine  Hydrochloride,  Squibb  15-gr.  vial, 

Hydrastincs  Hydrochloridum.  C2iH2iO6N.HCI.  White  to 
creamy-white,  odorless,  hygroscopic,  bitter  powder.  Soluble 
freely  in  water  or  alcohol;  slightly  in  chloroform;  very  spar- 
ingly in  ether.  Astringent,  Hemostatic,  Bitter  Tonic;  largely 
used  externally  (VlO  to  i/o  percent,  solution  or  1  percent,  oint- 
ment), in  gonorrhea,  conjunctivitis,  skin  diseases,  etc.  Dose: 
as  hydrastine  alkaloid.  Incompatible  with  alkalies,  borax,  tan- 
nic  acid,  in  solution. 

©  Hydrastinine  Hydrochloride,  Squibb 

15-gr.  vial,          ;  10-gr.  vial,          ;  5-gr.  vial, 

HydrastinintE  Hydrochloridum.  CnHuOoN.HCl.  Hydro- 
chloride  of  an  artificial  alkaloid  obtained  by  oxidation  of  hydras- 
tine.  Light-yellowish,  odorless,  very  bitter,  crystalline  powder. 
1  Gm.  dissolves  in  195  mils  (Cc.)  chloroform,  1820  ether;  very 
soluble  in  water  or  alcohol.  Uterine  Hemostatic,  Vaso-con- 
strictor;  chiefly  in  uterine  hemorrhage  and  congestion.  Average 
Dose:  Y2  grain  (0.03  Gm.). 


The  Squibb  Label  on  a  package  is  a  positive  guaranty  for  the 
.uniform  Purity  and  Reliability  of  the  product.  We  make  only 
ONE  quality:  the  SQUIBB  quality;  and  our  prices  are  as  low 
as  they  can  be  made  for  that  quality.  Specify  SQUIBB'S. 


128        SQUIBB'S  MATERIA  MEDICA 

HYDRASTIS. 

Hydrastis;  Golden  Seal;  Yellow  Puccoon;  Yellow  Rool, 
Dried  rhizome  and  roots  of  Hydrattis  canadensis  (Fam. 
Ranunculaceae) .  Assays  not  less  than  2.5  percent,  ether-soluble 
alkaloids.  Bitter  Tonic,  Astringent.  Average  Dose:  30  grains 
(2  Gm.).  (See  also  Fluidextract;  Tincture.) 

Hydrogen  Peroxide.     See  Solution  Hydrogen  Peroxide. 

0  Hyoscine     Hydrobromide.      Identical     with     Scopolamine 
Hydrobromide,  which  see. 

HYOSCYAMINE  HYDROBROMIDE  CRYSTALS. 

Hyoscyamince  Hydrobromidum.  Ci7H2aO3N.HBr.  White, 
nearly  odorless  crystals;  nauseous,  bitter  taste.  1  Gm.  dis- 
solves in  2.5  mils  (Cc.)  alcohol,  1.7  chloroform;  very  soluble 
in  water.  Average  Dose:  V200  grain  (0.0003  Gm.).  Anti- 
dotes: tannin,  emetics;  morphine,  pilocarpine  or  physostigmine. 

0  H yoscyamus,   Squibb 

Ground  for  Percolation  tin,  lb.         ;  %  Ib. 

Hyoscyamus.  Dried  leaves  and  flowering  or  fruiting  tops  of 
Hyoscyamus  niger  (Fam.  Solanacece),  yielding  not  less  than 
0.065  percent,  alkaloids.  Antispasmodic,  Sedative,  Analgesic. 
Average  Dose:  4  grains  (0.25  Gm.).  (See  also  Extract; 
Fluidextract;  Tincture.) 

0  HYPOPHYSIS  DESICCATED. 

Hypophysis  Sicca;  Desiccated  Pituitary  Body.  Newly  official. 
Posterior  lobe  of  pituitary  body  of  cattle  cleaned,  dried  and 
powdered.  Yellowish  or  grayish,  amorphous  powder;  charac- 
teristic odor.  Partially  soluble  in  water.  Stimulant  to  un- 
stnped  muscle,  Vaso-constrictor,  Parturient,  Hemostatic;  in  sec- 
ond stage  of  labor,  uterine  atony,  postpartum  hemorrhage, 
shock,  etc.  Average  Dose:  Yz  grain  (0.03)  Gm.).  (See  also 
Solution.) 

ICHTHALBIN. 

Ichthyol  Albuminate.  Gray-brown,  odorless,  almost  tasteless 
powder,  insoluble  in  ordinary  solvents;  75  percent,  ichthyol. 
Alterative,  Anlicatarrhal,  Vulnerary;  used  chiefly  in  place  of 
ichthyol  internally.  Dose:  5  to  30  grains  (0.3  to  2  Gm.). 
Externally  pure. 

ICHTHARGAN. 

Ichthyol-silver;  Silver  Sulphoichthyolate.  Brown,  nearly  in- 
odorous powder;  30  percent,  silver,  15  percent,  sulphur  organic- 
ally combined.  Soluble  in  water,  diluted  alcohol,  glycerin; 
insoluble  in  chloroform,  ether.  Astringent,  Antiseptic,  Anti- 
gonorrheic;  mostly  externally  in  i/2  *°  3  percent,  solution,  1  to 
10  percent,  ointment,  or  pure.  Dose:  i/is  to  1/4  grain  (0.004 
to  0.015  Gm.),  in  solution.  Dispense  solutions  in  dark  vials. 


SQUIBB'S  MATERIA  MED1CA        129 

ICHTHOFORM. 

Ichthyol-formaldehyde.  Blackish-brown,  nearly  odorless  and 
tasteless,  insoluble  powder.  Intestinal  Antiseptic  and  Anti- 
phlogistic, chiefly;  also  Vulnerary  (pure  or  mixed  with  talcum, 
etc.).  Dose:  10  to  30  grains  (0.65  to  2  Gm.). 

®  ICHTHYOL. 

Ammonium  Sulphoichthyolate.  Distillate  of  a  bituminous  shale, 
found  near  Seefeld  in  Tyrol,  containing  about  10  percent,  total 
sulphur,  55  percent,  of  which  is  organic.  Brown,  thick  liquid, 
of  bituminous  odor  and  taste.  Soluble  in  water;  insoluble  in 
alcohol  or  ether;  miscible  but  not  soluble  in  glycerin  and  oils. 
Antiphlogistic,  Astringent,  Alterative.  Used  chiefly  in  skin  and 
gynecological  diseases,  pure  or  5  to  50  percent,  ointment,  glyc- 
erin suspension,  etc.;  internally,  in  phthisis,  rheumatism,  nephri- 
tis, scrofula,  etc.  Dose:  3  to  30  minims  (0.2  to  2  mils  [Cc.]), 
in  pills  or  capsules.  Gives  precipitates  with  metallic  salts,  acids 
or  alkaloidal  salts;  decomposed  by  alkaline  hydrates  and  car- 
bonates, and  by  iodine  in  ointment  form.  For  deodorizing  ich- 
thyol  the  addition  of  2  percent,  each  of  oil  bergamot  and  oil 
eucalyptus  has  been  recommended.  Its  stains  are  removed  by 
boiling  the  fabric  in  soap  and  water,  or  by  washing  with  soft 
soap  or  soap  spirit. 

IGNATIA. 

Ignalia,  N.  F.;  Saint  Ignatius  Beans.  Dried  ripe  seeds  of 
Strychnos  Ignaiii  (Fam.  Loganiaceee),  yielding  not  less  than  2 
percent,  alkaloids.  Nearly  inodorous;  intensely  bitter.  Action 
same  as  of  nux  vomica.  Average  Dose :  1  grain  (0.065  Gm.) . 

Indicators.         See  under  Reagents,  etc.  (Part  IV). 

INFUSION  BRAYERA. 

Infusum  Brayerce,  N.  F.  6  Gm.  brayera  to  100  mils  (Cc.). 
Anthelmintic.  Average  Dose:  8  fluidounces  (240  mils  [Cc.]). 

INFUSION  CINCHONA. 

Infusum  Cinchona,  N.  F.  Each  100  mils  (Cc.)  represents  6 
Gm.  cinchona,  1  mil  aromatic  sulphuric  acid.  Average  Dose: 
12  fluidrachms  (45  mils  [Cc.]). 

INFUSION  DIGITALIS. 

Infusum  Digitalis.  1.5  Gm.  digitalis,  15  mils  (Cc.)  cinnamon 
water,  in  100  mils.  Must  be  made  fresh  as  wanted.  Average 
Dose:  1  fluidrachm  (4  mils). 

INFUSION  GENTIAN  COMPOUND. 

Infusum  Gentians  Composilum,  N.  F.  100  mils  (Cc.)  repre- 
sent 3  Gm.  gentian,  0.8  Gm.  each  coriander  and  bitter-orange 
peel.  Bitter  Tonic,  Appetizer.  Average  Dose :  4  fluidrachms 
(16  mils  [Cc.]). 

This  house  supplies  only  one  quality  of  each  produc. :  that  best 
suited  to  the  purposes  intended.  The  specification  "Squibb's" 
is  not  open  to  various  interpretations;  it  has  a  plain,  posi- 
tive meaning.  Therefore,  when  prescribing,  specify  SQUIBB'S. 


130        SQUIBB'S  MATERIA  MEDICA 


INFUSION  ROSE  COMPOUND. 

Infusum  Ross  Composilum,  N.  F.  100  mils  (Cc.)  represent 
1 .3  Gm.  red  rose,  0.9  mil  diluted  sulphuric  acid,  4  Gm.  sugar. 
Refrigerant,  Astringent;  Vehicle  for  saline  cathartics.  Average 
Dose:  3  fluidounces  (90  mils). 

INFUSION  SENNA  COMPOUND. 

Infusum  Sennce  Compositum.  100  mils  (Cc.)  represent  6  Gm. 
senna,  12  Gm.  each  manna  and  magnesium  sulphate,  2  Gm. 
fennel  as  corrigent.  Laxative.  Average  Dose:  4  fluidounces 
(120  mils).  Should  be  freshly  prepared. 

INFUSION  WILD  CHERRY. 

Infusum  Pruni  Virginians,  N.  F.  100  mils  (Cc.)  represent  4 
Gm.  wild  cherry,  5  mils  glycerin.  Bitter  Tonic.  Average  Dose: 
2  fluidounces  (60  mils  [Cc.]). 

INFUSORIAL  EARTH.    See  Silica. 

Inhaler,    Dr.    Ferguson's,    for   the    Administration    of 
Ether,  Chloroform,  Ethyl  Chloride,  Ethyl  Bromide 

or  anyone  of  the  so-called  Mixtures,  by  the  Open  Drop  Method. 

This  instrument,  invented  by  Dr. 
Robert  H.  Ferguson,  of  Boston, 
Mass.,  is  intended  to  administer 
only  air  saturated  with  ether  vapor, 
in  but  the  quantity  necessary  to 
produce  and  maintain  surgical  anass- 
thesia,  although  the  most  profound 
narcosis  may  be  had  with  it  if  de- 
sired. It  consists  of  a  wire  frame,  part  of  which  is  very 

flexible,  which   for  use  should  be  fitted  accurately   to   the  face 

of  the  patient  so  as  to  admit  no  air 

between    the    inhaler   and    the   face. 

Over  the  convex  diaphragm  enough 

gauze  is  stretched  to  hold  the  ether 

during  vaporization  but  in  no  n>ap  to 

limit  the  air  for  respiration,  see  Fig. 

2.    Onto  this  gauze  ether  is  dropped 

only  as  fast  as  it  Tvill  evaporate.  In 

order   to  prevent  the  dissipating  of 

the   vapor,    the    frame    is   covered   with    a   Canton    flannel   hood 

which  does  not  encroach  upon  the  opening  for  the  face  and 
which  is  drawn  up  on  top  so  as  to 
leave  an  opening  that  will  admit  at 
least  twice  as  much  air  as  the  pa- 
tient can  use  for  normal  breathing. 
Through  this  opening  (see  Fig.  1), 
the  ether  is  dropped  onto  the  gauze. 
This  inhaler  does  not  cover  or  in 
any  other  way  interfere  with  the 


FIG.  1. 


FIG.  3. 


SQUIBB'S  MATERIA  MEDICA        131 

Inhaler  (Cont.) 

eyes,  and  forcible  closure  of  the  jaws  is  not  possible  as  it  can- 
not go  below  the  chin.  It  can  be  bent  in  any  way  required  and 
thus  made  to  fit  any  adult  or  juvenile  face;  but  no  fitting  to  the 
face  of  a  very  young  child  or  infant  is  necessary  since  they 
require  only  very  small  amounts  of  ether  vapor.  Fig.  I  pictures 
the  inhaler  arranged  for  the  administration  of  ether,  ethyl  chlo- 
ride or  ethyl  bromide,  with  or  without  oxygen.  For  administering 
ether  with  the  <  patient  turned  completely  on  the  side  or 
so  it  looks  downward,  a  special  hood  with  the  only  opening  in 
the  side  should  be  used  (Fig.  3).  For  a  further  description 
of  the  Ferguson  Mask  see  the  article  by  Dr.  Ferguson  in  the 
/our.  Amer.  Med.  Assn.,  1905,  Dec.  30.  A  reprint  of  this 
paper  revised  by  the  author  in  1909  may  be  secured  free  by 
addressing  us.  Full  directions  for  use  accompany  each  instru- 
ment, which  is  put  up  in  a  neat  box  with  gauze  and  four 
hoods  (two  for  the  supine  position  and  one  for  the  right  lateral 
and  one  for  the  left  lateral  position).  The  instrument  is  small, 
light,  simple,  durable,  inexpensive,  and  can  easily  be  kept 
sterile.  Price:  Complete,  $2.50.  Single  hoods  for  either 
position,  each  20c. 

INULA. 

Inula,  N.    F.      Dried    rhizome    and    roots    of    Inula    Helenium 

(Fam.  Composite).      Aromatic    odor;     acrid,    bitter,    pungent 

taste.  Expectorant.     Average  Dose:  30  grains  (2  Gm.). 

INUNCTION  MENTHOL. 

Inunctum  Mentholis,  N.  F.  5  percent,  menthol  in  wool-fat. 
Counter-irritant,  Analgesic. 

INUNCTION  MENTHOL  COMPOUND. 

Inunclum  Mentholis  Composilum,  N.  F.  5  percent,  menthol, 
10  percent,  methyl  salicylate,  in  wool-fat.  Counter-irritant, 
Analgesic. 

loDALBIN. 

Compound  of  iodine  (21.5  percent.)  with  blood  albumin.  Red- 
dish powder,  nearly  tasteless,  of  peculiar  odor.  Soluble  in  al- 
kali solutions;  insoluble  in  ordinary  solvents.  Succedaneum  for 
alkali  iodides.  Dose :  5  to  15  grains  (0.3  to  1  Gm.). 

Iodine    Resublimed,    Squibb  g.  s.  bottle,  oz. 

lodum.  Heavy,  bluish-black,  friable  plates,  of  metallic  luster, 
distinctive  odor,  and  sharp,  acrid  taste.  Sp.  gr.  about  4.948.  I 
Gm.  dissolves  in  2950  mils  (Cc.)  water,  12.5  alcohol,  80 
glycerin;  freely  in  ether  or  chloroform;  in  solutions  alkali 
iodides.  Discutient  and  Counter-irritant  externally;  Alterative 
internally.  Average  Dose :  i/jo  grain  (0.005  Gm.),  in  dilute 


The  prices  of  the  Squibb  Products  are  in  all  instances  as  low  as 
the  quality  and  quantity  of  ingredients  and  the  expense  of  man- 
ufacture allow.  They  include  containers,  packing  and  boxing.  When 
ordering  or  prescribing  medicinal  products,  specify  SQUIBB'S. 


132       SQUIBB'S  MATERIA  MEDICA 

Iodine  Resublimed,  Squibb  (Cont.) 

solution.  Applied  externally  as  tincture,  ointment,  etc.  Incom- 
patible with  alkalies,  alkali  carbonates,  alkaloidal  salts,  tannin 
and  tannin -bearing  preparations,  etc.  Antidotes :  starchy  food 
in  abundance;  emetics.  (See  also  Tincture;  Reagents  [Part 
IV].) 

loDIPIN. 

Iodine  addition  products  of  fatty  acids  of  sesame  oil;  10  and 
25  percent,  iodine  respectively.  Yellow,  to  brownish-black, 
thick,  oily  liquids.  Alterative,  like  alkali  iodides.  Dose:  10%, 
1  to  2  fluidrachms  (4  to  8  mils  [Cc.]);  20%,  30  to  90  minims 
(2  to  6  mils). 

IODOCHLOROXYQUINOLINE.     See  Vioform. 

IODOFORM,  AROMATIZED. 

lodoformum  Aromatisalum,  N.  F.  lodoform  with  4  percent, 
coumarin. 

®  lodoform  Powdered,  Squibb 

bot.,  Ib.         ;  %  Ib.          ;  oz.          ;  1/8  oz. 

lodoformum;  Formyl  Triiodide;  Triiodonvethane.  CHIs-  Re-' 
purified,  precipitated  article  of  exceptional  purity  and  excel- 
lence;" we  continue  the  purification  beyond  the  stage  when  the 
product  is  of  the  purity  of  the  regular  market  article.  Fine 
powder,  much  lighter  and  less  gritty  than  ordinary  iodoform 
(which  is  composed  of  minute  crystal  fragments),  and  prefer- 
able as  a  dressing  for  wounds  and  suppurating  sores,  and  for 
making  ointments,  pills,  etc.  About  twice  as  bulky  as  ordinary 
iodo^form.hence  does  not  require  as  much  to  cover  any  surface. 
1  Gm.  dissolves  in  60  mils  (Cc.)  alcohol,  80  glycerin,  10  chlo- 
roform, 7.5  ether,  34  olive  oil ;  nearly  insoluble  in  water. 
Wound  Antiseptic,  Alterative,  Antitubercular.  Average  Dose: 
4  grains  (0.25  Gm.)  in  coated  pills.  Applied  pure,  in  oint- 
ments, paints,  solutions,  etc.  Incompatible  with  calomel,  silver 
salts,  chlorates  and  nitrites..  Antidotes:  emetics;  sodium  bicar- 
bonate, potassium  acetate;  chloral  hydrate;  morphine  hypoder- 
mically.  Keep  well-stoppered,  in  cool  place,  protected  from 
light. 

loDOTHYRINE. 

Thyroiodine.  Lactose  trituration  of  supposed  active  principle 
of  thyroid  gland;  1  Gm.  contains  0.0003  Gm.  iodine,  and  rep- 
resents 1  Gm.  fresh  thyroid.  Yellowish-white,  sweetish  powder. 
Alterative  and  Anticachectic.  Dose :  5  to  10  grains  (0.3  to  0.65 
Gm.). 

lOTHION. 

Diiodohydroxypropane.  Yellowish,  oily  liquid,  sp.  gr.  2.4  to 
2.5;  77  percent,  iodine.  Soluble  in  glycerin,  oils,  alcohol,  ether, 
chloroform;  insoluble  in  water.  Incompatible  with  alkalies. 
Substitute  for  iodine  and  iodides  for  endermic  medication.  Ap- 
plied in  25  to  50  percent,  ointments,  or  5  to  25  percent,  solutions 
in  olive  oil. 


SQUIBB'S  MATERIA  MEDICA        133 

0  Ipecac,  Squibb 

Powdered  for  Percolation  tin,  lb.        ;  %  lb. 

Ipecacuanha;  Ipecac  Root.  Dried  root  of  Cephaelis  Ipecacu- 
anha (Rio  Ipecac)  or  of  C.  acuminata  (Carthagena  Ipecac) 
(Fam.  Rubiacece),  assaying  not  less  than  1.75  percent,  ether- 
soluble  alkaloids.  Odor  slight;  taste  bitter,  nauseous,  some- 
what acrid;  powder  sternutatory.  Expectorant,  Emetic,  Ant- 
amebic,-  Stomachic.  Average  Dose :  expectorant,  etc.,  1  grain 
(0.065  Gm.) ;  emetic,  15  grains  (1  Gm.).  (See  also  Fluid- 
extract;  Syrup.) 

IRIS.     See  Orris  Root. 

IRIS  VERSICOLOR.    See  Blue  Flag. 

IRISH  Moss.    See  Chondrus. 

0  Iron  Reduced,  Squibb 

bottle,   lb.          ;    J4   lb.         ;    oz. 

Ferrum  ReJucium;  Iron  by  Hydrogen;  Quevenne's  Iron.  Fine, 
steel-gray,  lustrous  powder,  containing  not  less  than  90  percent. 
Fe.  Hematinic;  also  Reagent.  Average  Dose:  1  grain  (0.065 
Gm.),  in  pills  or  tablets. 

Iron  Albuminate,  Squibb 

bottle,  lb.          ;  %  lb.          ;  oz. 

Brown,  water-soluble  scales,  containing  25  percent,  ferric  oxide 
as  albuminate.  Hematinic.  Dose :  3  to  5  grains  (0.2  to  0.3 
Gm).  Also  used  for  conveniently  preparing  Solution  Iron 
Albuminate  N.  F. 

Iron  by  Hydrogen.         See  Iron,  Reduced. 

Iron  Cacodylate  Ampuls.      See  Ampuls. 

Iron  Carbonate  Mass.         See  Mass  Ferrous  Carbonate. 

Iron  Carbonate,  Precipitated.        See  Iron  Subcarbonate. 

Iron  Carbonate  Saccharated,  Squibb 

bottle,  lb.          ;  |4  lb. 

Fern  Carbonas  Saccharalus.  1 5  percent.  FeCOg,  Greenish- 
brown  powder;  odorless;  sweetish  then  slightly  ferruginous  taste. 
Partially  soluble  in  water.  Chalybeate  Tonic.  Average  Dose: 
4  grains  (0.25  Gm.).  Keep  well  stoppered. 

If  difficulty  is  experienced  in  procuring  any  Squibb  product, 
in  the  original  packages  here  listed,  please  notify  us;  we 
shall  see  that  your  wants  are  met  promptly  and  satisfactorily. 


134       SQUIBB'S  MATERIA  MEDICA 

0  Iron  Chloride  (Ferric),  Squibb  g.  s. botttle, oz. 

Fern  ChloriJum;  Ferric  Chloride;  Iron  Per-^Tri-,  or  Sesqul- 
chloride.  FeCls^H^O.  Crystalline,  deliquescent  pieces,  of 
orange-yellow  color  and  slightly  styptic  taste,  and  upon  solution 
and  testing  giving  no  evidence  of  oxychloride.  Contains  not  less 
than  20  percent,  iron.  1  Gm.  dissolves  in  0.2  mil  (Cc.)  water; 
freely  soluble  in  alcohol;  also  soluble  in  glycerin  or  ether. 
Styptic,  Hematinic.  Average  Dose:  1  grain  (0.065  Gm.). 
Keep  securely  stoppered.  (See  also  Reagents  [Part  IV].) 

IRON  CITRATE  GREEN. 

A  modification  of  U.  S.  P.  Iron  and  Ammonium  Citrate,  con- 
taining slightly  less  iron,  and  more  citric  acid  and  ammonium 
citrate  than  does  latter  and  acid  in  reaction.  The  Council  on 
Pharmacy  and  Chemistry,  of  the  American  Medical  Associa- 
tion, holds  that  th«  lower  content  of  iron,  as  well  as  the  acidity 
of  the  green  salt  would  appear  to  be  detriments  rather  than 
advantages.  We  have,  therefore,  discontinued  its  manufacture 
and  no  longer  supply  the  ampuls  formerly  furnished, 

Iron  Cyanide.        See  Iron  Ferrocyanide. 

Iron  Ferrocyanide,  Squibb 

bottle,  Ib.          ;  %  Ib.          ;  oz. 

Ferric  Ferrocyanide:  Insoluble  Prussian  or  Berlin  Blue;  In- 
soluble Iron  "Cyanide."  Fe4Fe3.(CN(j)s.  Dark-blue  powder. 
Insoluble  in  ordinary  solvents  and  dilute  acids.  Dose :  2  to  5 
grains  (0.13  to  0.3  Gm.). 

Iron  Glycerophosphate,  Squibb 

bottle,          ;  1/4  Ib.         ;  oz. 

Fern  Clycerophosphas,  N.  F.  Greenish-yellow,  odorless,  nearly 
tasteless  scales,  containing  a  variable  quantity  of  Feo(C3H7- 
O(;P)3,  corresponding  to  not  less  than  14  to  16  percent.  Fe. 
Slowly  soluble  in  water;  insoluble  in  alcohol.  Used  as  Hema- 
tinic, Nervine.  Average  Dose:  3  grains  (0.2  Gm.),  in  tablets 
or  pills. 

Iron  Hydroxide  with  Magnesium  Oxide.        See  Antidote, 
Arsenic. 

Iron  Hypophosphite,  Squibb  bottle,  J/4  Ib.  ;  oz. 
Fern'  Hypophosphis,  N.  F.  Fe(PHoOL>)3.  White  or  grayish- 
white,  odorless,  nearly  tasteless  powder.  Soluble  in  about  2300 
mils  (Cc.)  water,  more  readily  in  presence  of  hypophosphorous 
acid  or  alkali  citrate.  Hematinic.  Average  Dose:  3  grains 
(0.2  Gm.). 

IRON  LACTATE. 

Fern"  Lac  las,  N.  F.  Fe(C3H5O3)o.3H2O.  Greenish-white 
powder  or  masses;  slight  odor;  mild,  sweet,  ferruginous  taste. 
1  Gm.  dissolves  slowly  in  40  mils  (Cc.)  water;  soluble  in  solu- 
tions alkali  citrates;  almost  insoluble  in  alcohol.  Hematopoietic. 
Average  Dose:  5  grains  (0.3  Gm.). 


SQUIBB'S  MATERIA  MEDICA        135 

Iron  Lactophosphate,  Squibb 

bottle,  Ib.         ;   '/4  lb.         ;   oz.    - 

Greenish-white  powder.  Soluble  in  acidulated  water.  Contains 
about  44  percent,  ferrous  lactate  and  56  percent,  ferric  phos- 
phate. Hemarinic,  Alterative.  Dose:  2  to  5  grains  (0.13  to 
0.5  Gm.). 

IRON  MALATE  CRUDE.    See  Extract  Apples  Ferrated. 

Iron  Oxide  Saccharated,  Squibb       bottle,  lb.        ;   '/£  lb. 

Ferri  Oxidum  Saccharatum,  N.  F.;  Soluble  Ferric  Oxide; 
"Eisenzucker" ;  Iron  Sugar.  Reddish-brown  powder;  2.8  per- 
cent, iron.  Soluble  in  water.  Mild  Chalybeate.  Dose:  10  to 
20  grains  (0.65  to  1.3  Gm.). 

Iron  Peptonate,  Squibb 

bottle,  lb.         ;  %  lb.         ;  oz. 

Brown,  shining,  odorless  granules,  containing  about  25  per- 
cent, ferric  oxide  as  peptonate.  Nonastringent,  easily  assimilated 
Hematinic.  Dose:  2  to  5  grains  (0.13  to  0.3  Gm.).  Convenient 
and  very  satisfactory  for  making  Liquor  Ferri  Peplonati 
and  Liquor  Ferri  Peplonati  el  Mangani.  It  yields  perfectly 
clear,  brilliant,  palatable,  and  well-keeping  preparations.  Write 
for  working  formulas.  (See  also  Solution  Iron  Peptonate; 
Solution  Iron  Peptonate  and  Manganese;  Solution  Iron  Pep- 
tonate and  Manganese,  with  Arsenic.) 

Iron  Peptonate  and  Manganese,  Squibb 

bottle,  lb.          ;   %  lb.          ;   oz. 

Yellowish-brown,  freely  soluble  scales;  10  percent,  iron  and 
3.5  percent,  manganese.  Especially  designed  for  convenient 
preparation  of  Solution  Iron  Peptonate  and  Manganese;  35 
Gm.  suffice  to  make  1000  mils  (Cc.). 

Iron  Per=,  Sesqui=,  or  Tri-chloride.          See  Iron  Chloride, 
Ferric. 

Iron  Phenolsulphonate,  Squibb  bottle,  oz. 

Iron  Sulphocarbolate.  Highly  pure;  free  from  sulphates,  chlor- 
ides and  foreign  metals.  Readily  soluble  in  water.  Used  as 
Intestinal  Antiseptic  and  Astringent.  Dose:  3  to  l6  grains  (0.2 
to  0.65  Gm.). 


The  Squibb  products  are  recognized  everywhere  as  the  Quality 
Standard.  They  are  of  uniform  purity  and  strength,  hence 
theraupeutically  dependable.  When  ordering  or  prescribing  medi- 
cinal products,  you  will  do  well  always  to  specify  SQUIBB'S. 


136       SQUIBB'S  MATERIA  MEDICA 

©  Iron  Phosphate,  Squibb 

tin,    Ib.         ;    14    N>.         '.    °z. 

Fern  Phosphas;  Iron  Phosphate  Soluble.  Ferric  Phosphate 
rendered  soluble  by  sodium  citrate.  Slightly  acid,  green  scales, 
containing  not  less  than  12  percent,  iron.  Freely  soluble  in 
water;  insoluble  in  alcohol.  Hematinic,  only  slightly  astrin- 
gent. Incompatible  with  acids,  alkali  carbonates  and  tannin- 
containing  preparations.  Averge  Dose :  4  grains  (0.25  Gm.) 

Iron   Pyrophosphate,   Squibb 

tin,  Ib.          ;  %  Ib.         ;  oz. 

Fern'  Pyrophosphas,  N.  F.;  Iron  Pyrophosphate  with  Sodium 
Citrate.  Apple-green,  odorless  scales;  acidulous,  slightly  saline 
taste;  10  percent.  Fe.  Freely  soluble  in  water;  insoluble  in 
alcohol.  Hematinic;  used  largely  in  elixirs.  Average  Dose: 

4  grains  (0.25  Gm.). 

Iron   Subcarbonate,   Squibb  carton,  Ib.         ;  %  Ib. 

Fern'  Subcarbonas,  U.  S.  P.  1870;  Iron  Carbonate  Precipi- 
tated. Consists  chiefly  of  hydrated  oxide,  with  small  quantities 
of  ferrous  carbonate.  Reddish-brown,  odorless,  tasteless  pow- 
der. Insoluble  in  ordinary  organic  solvents.  Hematinic.  Dose : 

5  to   10  grains   (0.3  to  0.65  Gm.). 

Iron  Subsulphate,  Squibb  bottle,  %  Ib.        ;  oz. 

Basic  Ferric  Sulphate;  Monsel's  Salt.  Fe4O (504)5.  Light, 
reddish-brown,  deliquescent  powder;  readily  soluble  in  water, 
less  irritating  than  normal  ferric  sulphate  because  of  its  defi- 
ciency in  sulphuric  acid,  and  possesses  greater  astringency.  As- 
tringent, Styptic,  Hemostatic.  Dose:  2  to  5  grains  (0.13  to  0.3 
Gm.).  Keep  in  dry  place. 

Iron  Sugar.         See  Iron  Oxide  Red,  Sacrharated. 

©  Iron  Sulphate  (Cryst.),  Squibb 

bottle,  Ib.          ;    Y4   Ib. 

Fern  Sulphas;  Ferrous  Sulphate;  Iron  Protosulphate;  Green 
Vitriol.  FeSO}.7HL>O.  Well-crystallized,  and  not  less  than 
99.5  percent,  pure.  The  crystals  show  no  efflorescence  and  are 
free  from  uncombined  acid  and  aikali  metals.  Bluish-green 
prisms;  <plorless,  and  of  saline,  styptic  taste;  efflorescent  in  dry 
air,  and  rapidly  oxidizing  on  exposure  to  moist  air,  becoming 
coated  with  brownish-yellow  basic  ferric  sulphate.  1  Gm.  dis- 
solves in  1.4  mils  (Cc.)  water;  insoluble  in  alcohol.  Chalyb- 
eate Tonic,  Astringent.  Average  Dose:  U/2  grains  (0.1  Gm.). 
Keep  well  stoppered,  in  cool  dry  place.  (See  also  Reagents 
[Part  IV],  under  Ferrous  Sulphate). 


SQUIBB'S  MATERIA  MEDICA        137 

0  Iron  Sulphate  Dried,  Squibb       bottle,  Ib.        ;  J4  lb. 

Fern'  Sulphas  Exsiccatus;  Dried  Ferrous  Sulphate.  Ferrous 
Sulphate  deprived  of  its  water  by  efflorescence  and  heating, 
whereby  it  loses  35  percent,  of  its  weight.  Grayish-white  pow- 
der, completely  soluble  in  water.  Preferred  to  crystalline  salt 
for  administration  in  pill  form.  Average  Dose:  1  grain  (0.065 
Gm.). 

Iron  Sulphate   Granulated,   Squibb 

bottle,  lb.         ;  Y4  lb. 

Fern  Sulphas  Granulaius.  FeSO4-7H2O.  Pale-green,  crystal- 
line powder.  Convenient  form  of  ferrous  sulphate  for  dis- 
pensing purposes.  Action  and  dose,  as  iron  sulphate  crystals. 

Iron   Sulphocarbolate.        See  Iron   Phenolsulphonate. 

0  Iron  and  Ammonium  Citrate,  Squibb 

bottle,  lb.          ;  J4  lb.         ;  oz. 

Fern  el  Ammonii  Citras;  Soluble  Iron  Citrate;  Ammonio- ferric 
Citrate.  Garnet-red  scales;  odorless,  saline,  mildly  ferruginous 
taste.  Readily  and  completely  soluble  in  water;  insoluble  in 
alcohol.  Contains  equivalent  of  not  less  than  16  percent,  metal- 
lic iron.  Hematinic.  Average  Dose:  4  grains  (0.25  Gm.). 
Incompatible  with  mineral  acids,  vegetable  astringent  infusions, 
decoctions,  etc. 

Iron  and  Ammonium  Sulphate,  Squibb 

bottle,  lb.         ;  %  lb.          ;  oz. 

Fern"  el  Ammonii  Sulphas,  U.  S.  P.  VHIth  Rev.;  Ferric 
Ammonium  Sulphate.  FeNH4(SO4)2.12H2O.  Violet,  efflor- 
escent, styptic  crystals.  1  Gm.  dissolves  in  about  3  mils  (Cc.) 
water;  insoluble  in  alcohol.  Hematinic,  Astringent,  Styptic. 
Average  Dose:  8  grains  (0.5  Gm.).  (See  also  Reagents  [Part 
IV]  under  Ferric  Ammonium  Sulphate.) 

Iron  and  Ammonium  Tartrate,  Squibb 

bottle,  lb.         ;  %  lb.         ;  oz. 

Fern  et  Ammonii  Tartras,  U.  S.  P.  Vllth  Rev.  Garnet-red 
to  reddish-brown,  odorless  scales;  13  percent,  metallic  iron. 
Very  soluble  in  water;  insoluble  in  alcohol.  Non-astringent 
Chalybeate  Tonic.  Average  Dose:  4  grains  V0.25  Gm.). 

Iron  and   Manganese  Peptonate.     See  Iron   Peptonate   and 
Manganese. 


Since  we  make  only  one  quality  of  each  product,  that  best 
suited  to  the  purposes  intended,  the  specification  "Squibb's" 
is  not  open  to  various  interpretations,  but  has  a  plain,  positive 
meaning.  When  ordering  or  prescribing,  specify  SQUIBB'S. 


138       SQUIBB'S  MATERIA  MEDICA 

Iron  and  Potassium  Tartrate,  Squibb 

tin,  Ib.         ;  '/^  lb.         ;  oz. 

Fern'  et  Potassii  Tartras,  U.  S.  P.  Vllth  Rev.  Garnet-red  to 
reddish-brown,  odorless  scales,  of  sweetish,  ferruginous  taste; 
15  percent,  metallic  iron.  Soluble  freely  in  water;  insoluble  in 
alcohol.  Non-astringent  Hematinic.  Average  Dose:  4  grains 
(0.25  Gm.). 

Iron  and  Quinine  Citrate  (Soluble),  Squibb 

bottle,  lb.         ;  Y4  lb.         ;  oz. 

Fern'  et  Quinines  Cilras.  The  new  U.  S.  P.  has  adopted  this 
soluble  salt  and  dropped  the  regular,  difficultly  soluble  salt. 
Contains  not  less  than  1 1 .5  percent,  anhydrous  quinine  and  1 3 
percent,  iron.  Greenish  or  golden-yellow  scales;  odorless; 
bitter,  ferruginous  taste;  slightly  deliquescent.  Bitter  and 
Chalybeate  Tonic,  Antiperiodic.  Average  Dose:  4  grains 
(0.25  Gm.). 

Iron,  Quinine  and  Strychnine  Citrate,  Squibb 

bottle,  lb.         ;  '/^  lb.         ;  oz. 

Greenish,  very  bitter  scales;  0.9  to  1  percent,  strychnine.  Sol- 
uble in  water.  Tonic;  in  anemia,  chlorosis,  convalescence,  etc. 
Dose:  2  to  5  grains  (0.13  to  0.3  Gm.). 

Iron  and  Strychnine  Citrate,  Squibb 

bottle,  lb.          ;  %  lb.          ;  oz. 

Formerly  official.  Readily  soluble,  garnet-red  scales;  0-9  to  1 
percent,  strychnine  and  16  percent,  iron.  Nerve  Tonic,  Chaly- 
beate, Antiperiodic.  Ordinary  Dose:  2  grains  (0.13  Gm.). 

®Jaborandi.      See   Pilocarpus. 

JACKSON'S  PECTORAL  SYRUP.     See  Syrup  Morphine  and  Acacia. 

0  Jalap,   Squibb 

*  Ground  for  Percolation  tin,  lb. 

Powdered  tin,  lb.         ;  14  lb. 

Jalapa.  Dried  tuberous  root  of  Exogonium  Purga  (Fam.  Con- 
vo/vu/aceffi).  Assays  not  less  than  7  percent,  total  resin. 
Smoky,  sweetish  odor;  sweetish,  acrid  taste.  Hydragogue 
Cathartic,  especially  in  dropsies;  less  irritant  than  other 
resinous  cathartics.  Average  Dose:  15  grains  (1  Gm.).  Acts 
in  3  hours.  (See  also  Extract;  Powder;  Resin.) 

JAMESTOWN  WEED.     See  Stramonium. 

JANEWAY'S  PILLS.     See  Pills  Aloes  and  Podophyllum  Compound. 

JuGLANS. 

Juglans,  N.  F.;  Butternut  Bark.  Dried  inner  bark  of  roots 
of  Juglans  cinerea  (Fam.  J upland aceee) .  Cathartic.  Average 
Dose:  60  grains  (4  Gm.). 


SQUIBB'S  MATERIA  MEDICA        139 

JUNIPER  BERRIES. 

Juniperus,  N.  F."  Dried  ripe  fruit  of  Juniperus  communis 
(Fam.  Pinacea).  Odor  aromatic;  taste  sweet,  pleasant,  tere- 
binthinate,  slightly  bitter.  Irritant  Diuretic.  Average  Dose: 
60  grains  (4  Gm.).  (See  also  Fluidextract.) 

Kaolin,  Medicinal,  Squibb  carton,  lb. 

Kaolinum,  N.  F.  Offered  in  response  to  the  demand  from  physi- 
cians for  a  pure,  finely  powdered,  sterilized  product,  for  in- 
ternal use.  Native  aluminum  silicate  (H^AloSioOg).  Grayish- 
yellow,  fine  powder;  clay-like  taste  and  odor;  almost  insoluble 
in  ordinary  solvents.  Purified,  dried  and  sterilized.  Specially 
intended  for  medicinal  use,  as  absorbent  and  eliminant  .of  patho- 
genic bacteria  in  diphtheria,  typhoid  fever,  intestinal  tubercu- 
losis; also  used  as  dusting  powder  in  wounds  and  skin  diseases, 
for  clarifying  liquids,  and  as  pill-excipient  for  potassium  per- 
manganate, gold  chloride  and  silver  nitrate.  Dose:  8  to  16 
heaping  teaspoonfuls  one  to  three  times  daily,  on  empty  stomach, 
suspended  in  a  little  water  or  oatmeal  gruel.  Topically,  for 
removing  bacilli  from  throat,  one-third  teaspoonful  is  swallowed 
as  slowly  as  possible  every  ten  to  fifteen  minutes  during  th« 
day  until  bacilli  have  completely  disappeared. 

Kaolin  Poultice.        See  Cataplasm  Kaolin. 

KAVA. 

Kava,  N.  F.;  Kava  Kava.  Dried  rhizome  of  Piper  methysli- 
cum  (Fam.  Piperacece).  Odor  faint  but  characteristic;  taste 
aromatic,  pungent,  slightly  bitter.  Mild  Diuretic,  Genito- 
urinary Stimulant;  similar  to  cubeb.  Average  Dose:  15  grains 
(1  Gm.). 

KELENE.    Brand  of  Ethyl  Chloride.  „ 

KERMES  MINERAL.    See  Antimony  Sulphurated. 

KIESELGUHR.     See  Silica. 

KINO. 

Kino.  Spontaneously  dried  juice  of  Plerocarpus  Marsupium 
(Fam.  Leguminosat).  Reddish-brown  to  reddish-black,  brittle, 
odorless  fragments;  astringent  taste.  Slightly  soluble  in  water; 
almost  completely  in  alcohol ;  nearly  insoluble  in  ether.  Intes- 
tinal and  Pharyngeal  Astringent.  Average  Dose:  8  grains  (0.5 
Gm.).  (See  also  Tincture.) 

KOLA. 

Kola,  N.  F.;  Cola.  Dried  cotyledons  of  several  species  of 
Cola  (Fam.  Sterculiacea),  yielding  not  less  than  1.5  percent, 
caffeine.  Odorless;  slightly  astringent  taste.  Stimulant,  Muscle- 
invigorator.  Average  Dose:  60  grains  (4  Gm.). 

The  founder  of  the  House  of  Squibb,  Dr.  Edward  R.  Squibb, 
not  only  had  high  ideals,  but  lived  and  labored  for  them;  and, 
in  the  words  of  William  Miller  Bartlett,  "the  House  of  Squibb 
stands  today  as  a  living  monument  to  the  honor,  integrity,' zeal 
and  devotion  of  its  founder." 


140        SQUIBB'S  MATERIA  MEDICA 

Kousso.    See  Brayera. 

Krameria,  Squibb 

Ground  for  Percolation  tin,  lb. 

Krameria,  N.  F.;  Rhatany.  Dried  root  of  Krameria  IriaaJra, 
K.  Ixina,  and  K.  argenlea  (Fam.  Krameriacea) .  Powerful 
Astringent;  chiefly  in  diarrhea.  Average  Dose:  15  grains  (I 
Gm.).  (See  also  Extract;  Fluidextract;  Syrup;  Troches 
[Part  II).) 

KUMYSS. 

Lac  Fermentatum,  N.  F.  Sweetened  cow's  milk  fermented  with 
yeast.  Refrigerant  Nutritive.  Average  Dose:  8  fluidounces 
(240  mils  [Cc.]). 

LACTOPHENIN. 

Lactylparaphenetidin.  Cp^OCoHsNH.COCH.OH.CHa. 

Colorless,  odorless,  faintly  bitter  powder.  Soluble  in  8.5  parts 
alcohol,  330  water.  Antipyretic,  Analgesic.  Dose:  8  to  15 
grains  (0.5  to  I  Gm.). 

Lactose.     See  Sugar  of  Milk. 

LACTUCARIUM. 

Laclucarium.  Dried  milk-juice  of  Lacluca  vtrosa  (Fam.  Com- 
posite). Irregular,  grayish-brown  pieces;  opium-like  odor; 
bitter  taste.  Partially  soluble  in  alcohol  or  ether;  practically 
insoluble  in  water.  Nerve  Sedative,  Anodyne;  in  nervousness, 
irritative  cough,  etc.  Average  Dose:  15  grains  (1  Gm.). 

LADIES'  SLIPPER.     See  Cypripedium. 

LADY  WEBSTER'S  DINNER  PILLS.     See  Pills  Aloes  and   Mastic. 

LAFAYETTE  MIXTURE.     See  Mixture  Copaiba. 

LAMOTTE'S    DROPS.     See    Tincture    Iron   Chloride    Ethereal. 

Lanolin.        See  Wool-fat. 

LAPPA. 

Lappa,  N.  F. ;   Burdock.     Dried  root  of  Arciium  Lappa  (Fam. 

Composites).     Slight  odor;    taste  mucilaginous,  sweetish,  slightly 

bitter.      Used    as    Alterative.      Average    Dose:    30    grains    (2 

Gm.)      (See  also  Fluidextract.) 

0  LARD. 

Adeps.  Purified  internal  fat  of  abdomen  of  hog  (Sus  scrofa). 
InsoluHe  in  water;  very  slightly  soluble  in  alcohol,  readily  in 
ether  or  chloroform. 

0  Lard  Benzoinated,  Squibb  tin,  lb. 

Adeps  Benzoinalus.  Pure  lard  carefully  benzoinated  with  1 
percent.  Siam  gum  benzoin.  Mildly  Antiseptic.  Emollient; 
Ointment  Base.  Liable  to  granulate  on  keeping;  store  in  a 
very  cool  place. 


SQUIBB'S  MATERIA  MEDICA        141 

LARKSPUR  SEED. 

Delphinium,  N.  F.  Dried  seeds  of  Delphinium  Consolida  or 
of  D.  Ajacis  (Fam.  Ranunculacea) .  Faint  odor;  bitter  then 
biting  and  acrid  taste.  Antiparasitic.  (See  also  Fluidextract.) 

LAROSAN. 

Casein-Calcium.  Light,  white,  almost  odorless  and  tasteless 
powder.  Soluble  in  water.  Addition  to  milk  taken  by  infants 
suffering  with  diarrhea. 

LASSAR'S  DERMATOLOGIC  PASTES.    See  under  Paste. 
Laudanum.         See  Tincture  Opium. 

Lavender  Compound  Ground,  Squibb  tin,  Ib. 

A  mixture  of  the  ground  drugs  Saigor.  cinnamon,  cloves,  nutmeg 
and  red  saunders,  in  the  proportions  called  for  in  U.  S.  P. 
formula  for  Tincture  Lavender  Compound. 

®  Lead  Acetate,  Squibb  tin,  Ib.         ;  14  Ib. 

Plumbi  Acetas;  Sugar  of  Lead,  Pb(C2H3Oo)2.3H2O.  Made 
by  a  special  process  devised  in  the  Squibb  Laboratories  and 
which  produces  an  exceedingly  pure  article,  far  superior  to  that 
commonly  offered.  Colorless,  granular  crystals,  of  faintly 
acetous  odor,  and  sweetish,  astringent,  metallic  taste;  efflores- 
cent and  absorbing  carbon  dioxide  on  exposure.  1  Gm.  dissolves 
in  1.4  mils  (Cc.)  water,  38  alcohol,  5  glycerin.  Astringent, 
Styptic;  in  conjunctivitis,  gonorrhea,  ivy  poisoning,  diarrhea, 
gastric  hemorrhage,  etc.  Average  Dose:  I  grain  (0.065  Gm.). 
Incompatible  with  acids,  tannin,  vegetable  astringent  infusions 
and  tinctures,  carbonates,  hydroxides,  iodides,  chlorides,  sul- 
phates, etc.  Antidotes:  sodium  or  magnesium  sulphate,  emetics; 
white  of  egg;  demulcents.  (See  also  Reagents  [Part  IV].) 

LEAD  CARBONATE. 

Plumbi  Carbonas,  N.  F.;  White  Lead.  Mixture  of  lead  car- 
bonate and  hydroxide.  Heavy,  white,  odorless,  tasteless  pow- 
der. Insoluble  in  ordinary  solvents.  External  Antiseptic;  as 
dusting  powder,  ointment,  etc. 

LEAD  IODIDE. 

Plumbi  lodidum,  N.  F.;  PbI2.  Dropped  from  U.  S.  P. 
Heavy,  yellow  powder;  odorless  and  tasteless.  1  Gm.  dissolves 
in  about  1300  mils  (Cc.)  water;  soluble  in  fixed  alkali  solu- 
tions, slightly  in  alcohol.  Discutient,  Alterative;  externally  in 
10  to  20  percent,  ointments,  in  indolent  ulcers,  swollen  glands, 
etc.;  internally  in  scrofula,  phthisis,  etc.  Dose:  V°  to  1  grain 
(0.03  to  0.065  Gm.) 

Lead  Oxide  Red,  Reagent.       See  Reagents  (Part  IV). 


The  Squibb  Ideals  have  taken  concrete  form  in  the  Squibb 
Products;  these  are  universally  recognized  as  standards  of 
uniform  Purity  and  Efficacy,  that  is,  general  Excellence  and 
Reliability.  Specify  SQUIBB'S  when  prescribing  or  ordering. 


142        SQUIBB'S  MATERIA  MEDICA 

LEAD  OXIDE,  YELLOW. 

Plumbi  Oxidum;  Litharge.  PbO.  Heavy,  reddish-yellow, 
odorless,  tasteless  powder.  Insoluble  in  ordinary  solvents.  Used 
pharmaceutically  and  technically.  (See  also  Reagents  [Part 
IV].) 

Lead  Peroxide  Reagent.        See  Reagents  (Part  IV). 

LEMON  PEEL. 

Limonis  Cortex.  Outer  rind  of  fresh  ripe  fruit  of  Ctlrus 
medico  Limonum  (Fam.  Rulaced),  (See  also  Tincture.) 

LEPTANDRA. 

Leptandra,  N.  F.;  Culver's  Root.  Dried  rhizome  and  roots 
of  Veronica  virginica  (Fam.  Scrophulariacea).  Slight  odor; 
taste  bitter,  slightly  acrid.  Cathartic,  similar  to  podophyllum. 
Average  Dose:  15  grains  (1  Gm.).  (See  also  Extract) 

Licorice  Root  Powdered,     See  Glychrrhiza. 

LIFE   ROOT.     See   Senecio. 

LILY  OF  THE  VALLEY  FLOWERS.    See  Convallaria  Flowers. 

LILY  OF  THE  VALLEY  ROOT.    See  Convallaria  Root. 

©  Lime,  Squibb  bottle,  lb. 

Calx;  Calcium  Oxide;  Quicklime;  Burnt  Lime.  A  well- 
burnt  article,  satisfactorily  free  from  carbonate,  containing  no 
more  than  allowable  impurities,  and  of  not  less  than  95  per- 
cent. CaO.  Hard,  white,  or  grayish-white  masses,  on  exposure 
attracting  moisture  and  carbon  dioxide  and  falling  to  a  white 
powder;  odorless;  caustic  taste.  I  Gm.  dissolves  in  840  mils 
(Cc.)  water;  soluble  also  in  glycerin  and  syrup;  insoluble  in 
alcohol.  With  about  half  its  weight  of  water  it  becomes  heated 
••and  converted  into  calcium  hydroxide  (slaked  lime).  Antacid, 
•Caustic,  Depilatory.  Given  internally  as  lime  water  or  syrup 
ilime  usually.  Applied  externally  (to  cancers,  old  ulcers,  etc.) 
in  substance  or  25  percent,  paste.  Keep  bottle  securely  stop- 
pered and  in  a  dry  place.  (See  also  Reagents*  [Part  IV], 
under  Calcium  Oxide.) 

©  Lime  Chlorinated,  Squibb  bottle,  lb. 

Calx  Chlorinata;  Chlorinated  Calcium  Oxide;  so-called  "Chlo- 
ride of  Lime";  Bleaching  Powder.  Indefinite  composition, 
chiefly  CaOClo.  Of  unusually  high  test,  assaying  when  fresh 
about  35  percent,  of  available  chlorine,  not  only  30  percent,  as 
U.  S.  P.  requires.  Since  the  value  of  chlorinated  lime  de- 
pends upon  the  amount  of  available  chlorine  which  may  slowly 
be  given  off,  it  will  be  found  more  economical  to  use  this  arti- 
cle than  one  of  lesser  strength.  White  or  grayish-white  powder, 
of  penetrating  odor,  and  repulsive  saline  taste;  gradually  decom- 
poses on  keeping.  Partially  soluble  in  water  or  alcohol.  Used 
chemically  and  as  bleaching  agent,  also  General  Disinfectant. 
Antidotes:  ammonia  by  inhalation  or  by  mouth;  albumen;  apo- 
morphine  subcutaneously  as  emetic,  if  overdose  was  taken  by 
mouth. 


SQUIBB'S  MATERIA  MEDICA        143 

Lime  Hydrated,  Squibb 

For  Lime  Water  4-drachm  vials,  per  doz. 

Pure  Hydrated  Lime  specially  designed  for  convenient  prepara- 
tion of  Lime  Water.  Add  contents  of  vial  to  1  gallon  distilled 
water,  shake  briskly  and  repeat  shaking  several  times  during 
half  an  hour.  The  water  will  then  be  saturated,  and  the 
excess  of  lime  will  settle  and  should  be  allowed  to  remain  in 
the  bottle  to  insure  constant  saturation.  NOTE:  The  entire 
contents  of  a  vial  should  be  used  up  at  one  operation;  it  will 
not  do  to  employ  a  portion  of  them  at  a  later  date. 

Lime    Sulphurated.       See  Calcium  Sulphide  Crude. 

LIME  JUICE. 

Succus  Ciiri,  N.  F.  Expressed  fresh  juice  of  ripe  fruit  of 
Citrus  medico  acida  (Fam.  Rutacece).  Each  100  mils  (Cc.) 
contains  5  to  10  Gm.  acids.  Antiscorbutic,  Refrigerant,  Anti- 
septic. 

LIME  JUICE  AND  PEPSIN. 

Succus  Citri  el  Pepsini,  N.  F.  Glycerite  pepsin  40  vol.  percent., 
lime  juice  60.  Each  fluidounce  contains  about  16  grains  pepsin. 
Digestive.  Average  Dose:  2  fluidrachms  (8  mils  [Cc.]). 

LIME  WATER.     See  Solution  Calcium  Hydroxide. 

LINIMENT  ACONITE  AND  CHLOROFORM. 

Linimentum  Aconiti  el  Chloroform!,  N.  F.  100  mils  (Cc.) 
contain  4.5  mils  fluidextract  aconite  and  12.5  mils  chloroform, 
with  soap  liniment  and  alcohol.  Anodyne  embrocation.  Anti- 
dotes: emetics;  demulcents;  atropine,  digitalis,  ammonia. 

®  LINIMENT  AMMONIA. 

Linimenlum  Ammonia;  Volatile  Liniment.  1  volume  ammonia 
water  and  3  volumes  sesame  oil.  Stimulant  and  Anodyne 
embrocation. 

LINIMENT  AMMONIUM  IODIDE. 

Linimenlum  Ammonii  lodidi,  N.  F.  Iodine,  ammonia  water, 
camphor,  oils  rosemary  and  lavender,  and  alcohol.  Contains 
about  0.5  percent,  ammonium  iodide.  Discutient. 

LINIMENT  BELLADONNA. 

Linimentum  Belladonnas.  100  mils  (Cc.)  contain  5  Gm.  cam- 
phor in  fluidextract  belladonna  root.  Anodyne. 

®  Liniment    Camphor,    Squibb  bottle,  pint 

Linimentum    Camphors;    Camphorated    Oil.  100   mils    (Cc.) 

contain  20  Gm.  camphor  in  cotton-seed  oil.  Anodyne,  Rube- 
facient. 


The  Squibb  Label  on  a  package  is  a  positive  guaranty  for  the 
uniform  Purity  and  Reliability  of  the  product.  We  make  only 
ONE  quality:  the  SQUIBB  quality;  and  our  prices  are  as  low 
as  they  can  be  made  for  that  quality.  Specify  SQUIBB'S. 


144       SQUIBB'S  MATERIA  MEDICA 

LINIMENT  CANADA.     See  Liniment  Opium  Compound. 
LINIMENT  CANTHARIDES.  bottle,  pint 

Representing    about    15    percent,    cantharides    in    oil    turpentine. 

Rubefacient,  Counter-irritant.     Antidotes:  emetics;   demulcents; 

morphine  subcutaneously. 

0  Liniment  Chloroform,  Squibb  bottle,  pint 

Linimenium  Chloroformi.  3  volumes  chloroform  with  7  vol- 
umes soap  liniment.  Anodyne. 

LINIMENT  CROTON  OIL. 

Linimenium  Tiglli,  N.  F.  13  vol.  percent,  croton  oil,  43  oil 
cajuput  and  44  alcohol.  Counter-irritant,  Rubefacient.  Antidotes: 
emetics;  oil  or  mucilage;  atropine  hypodermically ;  cocaine. 

LINIMENT  CROTON  OIL  COMPOUND. 

Linimentum  Tiglii  Compositum,  N.  F.  20  volume  percent,  each 
oils  croton,  sassafras  and  turpentine,  with  40  olive  oil.  Counter- 
irritant. 

0  LINIMENT  LIME. 

Linimenium  Calcis;  Carron  Oil.  Equal  volumes  lime  water  and 
linseed  oil.  Emollient,  Protective,  Anodyne;  in  burns  chiefly. 

LINIMENT  MUSTARD  COMPOUND. 

Linimentum  Sinapis  Composilum,  N.  F.  Each  100  mils  (Cc.) 
contains  3  mils  volatile  oil  mustard,  20  mils  fluidextract  meze- 
reum,  6  Cm.  camphor,  1 5  mils  castor  oil,  with  alcohol.  Counter- 
irritant,  Rubefacient. 

LINIM-ENT  OPIUM  COMPOUND. 

Linimenium  Opii  Compositum,  N.  F.;  Canada  Liniment.  10 
vol.  percent,  tincture  opium,  with  camphor  (1 .75  percent.),  oils 
turpentine  and  peppermint,  ammonia  water  and  alcohol.  Ano- 
dyne. Antidotes:  emetics;  atropine  or  strychnine  hypodermi- 
cally; demulcents. 

0  Liniment  Soap,  Squibb  bottle,  pint 

Linimenium  Saponis;  Liquid  Opodeldoc;  Camphorated  Tinc- 
ture Soap.  Each  100  mils  (Cc.)  contains  6  Gm.  dried  soap, 
4.5  Gm.  camphor,  and  1  mil  oil  rosemary  as  perfume,  with 
alcohol  and  water. 

LINIMENT  SOAP  CAMPHORATED. 

Linimenium  Saponalo-Camphoralum,  N.  F.;  Solid  Opodeldoc. 
A  soft  solid,  containing  soap,  camphor,  oils  thyme  and  rose- 
mary, alcohol,  and  stronger  ammonia  water.  Stimulating  Anodyne. 

Liniment  Soap  Soft,  Squibb  bottle,  pint 

Linimenium  Saponis  Mollis;  Tincture  Green  Soap.  100  mils 
(Cc.)  oontam  65  Gm.  soft  soap  and  2  mils  oil  lavender,  with 
alcohol.  Detergent  and  Antipruntic,  for  use  by  surgeons  and 
dermatologists,  as  well  as  for  shampooing.  Its  alkalinity  is 
very  slight,  merely  sufficient  to  prevent  rancidity. 


SQUIBB'S  MATERIA  MEDICA        145 

LINIMENT  SOAP  SOFT,  COMPOUND. 

Linimentum  Saponis  Mollis  Composition,  N.  F.;  Compound 
Tincture  Green  Soap.  100  mils  (Cc.)  contain  15  Gm.  soft 
soap,  2  mils  oil  cade,  and  alcohol.  Antiparasitic  Dermic. 

Liniment,  Stokes'.        See  Liniment  Turpentine  Acetic. 
Liniment,   St.  John   Long's.    See  Liniment  Turpentine  Acetic. 
LINIMENT  TURPENTINE. 

Ferri  el  Ammonii  Cilras;  Soluble  Iron  Citrate;  Ammonio- ferric 

turpentine.      Counter-irritant,    Rubefacient. 

Liniment  Turpentine  Acetic,  Squibb  bottle,  pint 

Linimentum  Terebinthins  Acellcum,  N.  F.;  Stokes'  or  St.  John 
Long's  Liniment;  Linimentum  Album.  40  vol.  percent,  oil 
turpentine,  with  egg,  oil  lemon,  acetic  acid  and  rose  water. 
Counter-irritant. 

©  LINSEED. 

Linum;  Flaxseed.  Ripe  seeds  of  L'tnum  usilaiissimum  (Fam. 
Linaceee).  Demulcent,  Emollient. 

Liquid  Court  Plaster.     See  Collodion  Flexible. 

©  Liquid  Petrolatum,  Squibb 

Heavy  (Californian)  1  -pint  bottles,  per  <3oz. 

Petrolatum  Liquidum ;  Mineral  Oil,  Heavy  Californian.  Spe- 
cially repurified  for  medicinal  use.  Numerous  comparative  tests 
made  by  us  show  this  Californian  oil  to  differ  in  essential  respects 
from  other  American  oils  and  to  be  superior  to  the  best  Rus- 
sian oils  known  to  us.  Therefore  we  have  selected  this  Cali- 
fornian Heavy  Oil,  of  high  viscosity  and  high  specific  gravity, 
as  the  best  and  now  supply  it  on  all  orders.  Concerning  it 
the  following  facts  are  important:  It  is  refined  under  our  con- 
trol, and  exclusively  for  us,  by  The  Standard  Oil  Company  of 
California.  It  is  pure;  free  from  paraffins,  inorganic  matter, 
organic  sulphur  compounds  and  all  injurious  hydrocarbons  such 
as  anthracene*,  phenanthrene,  chrysene  and  oxidized  acid  and 
basic  bodies.  It  is  colorless,  odorless  and  tasteless;  has  the 
very  high  sp.  gr.  0.886  to  0.895  at  15°  C,  or  0.881  to  0.890 
at  25°  C.;  and  it  has* an  exceptionally  high  natural  viscosity — 
which  is  of  supreme  importance  because  the  value  of  liquid 
petrolatum  is  said  to  reside  in  lubrication,  and  true  viscosity 
to  be  the  chief  index  of  lubricating  power.  Liquid  Petrolatum 
Squibb  is  prescribed  to  prevent  or  relieve  intestinal  stasis,  con- 
stipation, colitis  and  allied  conditions;  to  prevent  or  relieve 
hemorrhoids;  to  regulate  the  mother's  bowels  during  pregnancy 
and  lactation,  as  its  effect  does  not  pass  from  mother  to  child. 
It  is  not  a  purgative,  a  cathartic,  or  a  laxative,  but  a  mechan- 


This  house  supplies  only  one  quality  of  each  product:  that  best 
suited  to  the  purposes  intended.  The  specification  "Squibb's" 
is  not  open  to  various  interpretations;  it  has  a  plain,  posi- 
tive meaning.  Therefore,  when  prescribing,  specify  SQUIBB'S. 


146        SQUIBB'S  MATERIA  MEDICA 

©  Liquid  Petrolatum,  Squibb  (Cont.) 

ical  lubricant.  It  is  not  absorbed  by  the  stomach  or  intestine, 
does  not  act  on  and  is  not  acted  upon  by  the  fluids  of  the 
gastro-intestinal  tract,  and  passes  out  of  the  body  in  exactly  the 
same  condition  and  quantity  that  it  entered.  During  its  pas- 
sage it  lubricates  the  lumen  of  the  gut,  softens  the  feces,  pre- 
vents injury  of  the  mucous  membrane  by  scybala,  allows  repair 
of  an  already  abraded  mucosa,  relieves  irritated  or  fatigued 
myenteric  ganglia,  and  thus,  by  permitting  a  rapid  passage 
of  the  intestinal  contents,  prevents  the  proliferation  of  bacteria 
and  the  production  of  toxins  and  a  consequent  auto-intoxication. 
In  short,  its  use  establishes  and  maintains  a  proper  body  drain- 
age, allowing  better  digestion  and  absorption  of  food.  In 
surgery  it  is  used  as  an  aid  in  differentiating  a  surgical  intes- 
tinal case  from  one  non-surgical ;  also  as  a  prophylactic  to  pre- 
vent the  ascent  of  intestinal  bacteria,  thereby  preventing  sec- 
ondary infection  of  biliary  and  other  ducts.  In  the  peritoneal 
cavity  it  is  used  to  prevent  adhesions  or,  by  Burrows'  method, 
to  forestall  post-operative  stasis.  It  is  useful  as  a  dressing  for 
burns,  also  for  nasal  packings  and  spray.  Liquid  Petrolatum 
Squibb  sprays  better  than  does  a  light  oil,  and  lubricates  the 
nasal  mucosa  more  thoroughly  and  the  lubrication  is  more  last- 
ing. Dosage :  As  pure  liquid  petrolatum  has  no  physiological 
action,  it  may  be  given  in  any  quantity  without  harm.  As  :I 
is  not  chemically  active  and  resists  chemical  change,  it  is  com- 
patible with  any  medication  indicated.  However,  certain  facts 
about  dosage  are  worthy  of  note.  The  length  and  calibre 
of  the  gastro-intestinal  tract  differ  not  only  with  age  but  in 
different  individuals  of  the  same  age.  Therefore  the  quantity 
of  oil  necessary  for  lubrication  will  vary.  The  conditions  for 
which  heavy  liquid  petrolatum  is  indicated  are  various,  so  the 
size  and  number  of  doses  may  vary.  For  instance,  there  must 
be  considered  the  nature,  amount,  and  consistency  of  the  con- 
tents of  the  bowel;  the  pathological  relaxation  or  hypertonicity 
of  the  intestinal  walls;  the  degree  of  entero-  or  viscero-ptosis; 
the  number,  kind  and  place  of  adhesions,  bands  or  kinks;  also 
whether  the  life  of  the  patient  is  active  or  sedentary.  Larger 
and  more  frequent  doses  are  necessary  at  the  beginning  of 
treatment  than  after  a  normal  intestinal  condition  has  been 
established.  In  every  case  a  minimum  regulating  dose  should 
be  determined  and  maintained,  not  because  more  oil  would  do 
harm,  but  because  it  would  be  wasted.  Intestinal  lubrication 
can  be  produced  best  when  the  tract  is  comparatively  empty. 
The  best  time  for  administration,  then,  is  between  meals  and 
at  bedtime.  However,  individual  preferences  for  other  times 
may  be  gratified.  An  ordinary  dose  for  adults  is  one  table- 
spoonful  between  meals  and  two  tablespoonfuls  on  going  to  bed. 
Children  and  infants  need  only  smaller  quantities.  As  Liquid 
Petrolatum  Squibb  is  odorless  and  tasteless,  flavoring  or  a 
menstruum  is  not  necessary,  although  such  may  be  added  if 
desired.  When  prescribing  mineral  oil,  specify  Liquid  Petro- 
latum Squibb,  and  thereby  assure  a  pure,  heavy,  and  viscous 
mineral  oil  of  the  highest  quality. 


SQUIBB'S  MATERIA  MEDICA        T47 

Liquorice.     See  Glycyrrhiza. 
LITHARGE.     See  Lead  Oxide  Yellow. 
Lithium  Benzoate,  Squibb 

*From  Synthetic  Acid  bottle,  %  Ib.         ;  oz. 

From  Natural  (True)  Acid  bottle,  J4  Ib.  ;  oz. 
Lithii  Benzoas,  U.  S.  P.  Vllth  Rev.  LiC7H5O2.  White 
powder  or  scales;  odorless  or  faint  benzoin  odor;  cooling, 
sweetish  taste.  Soluble  in  3  parts  water,  13  alcohol;  aqueous 
solubility  increased  by  sodium  benzoate  and  lessened  by  alco- 
hol. Used  as  Antirheumatic,  Internal  Antiseptic.  Average 
Dose:  1  Gm.  (15  grains). 

Lithium  Bromide,  Squibb  bottle,  %  Ib.         ;  oz. 

Lithii  Bromidum.  LiBr.  White,  granular,  odorless,  very  deli- 
quescent salt;  sharp,  slightly  bitter  taste.  1  Gm.  dissolves  in 
0.6  mil  (Cc.)  water;  freely  soluble  in  alcohol,  moderately  in 
ether.  Nerve  Sedative.  Average  Dose:  15  grains  (1  Gm.). 
Incompatible  with  alkaloidal  salts  in  solution.  Must  be  kept 
securely  stoppered,  in  dry  place. 

Lithium  Carbonate,  Squibb 

carton,  Ib.         ;  ]/4  Ib.         ;  oz. 

Lithii  Carbonas.  Li2CC>3.  White,  light,  odorless  powder,  of 
alkaline  taste.  1  Gm.  dissolves  in  78  mils  (Cc.)  water,  140 
boiling  water;  more  freely  soluble  in  water  saturated  with 
carbon  dioxide;  almost  insoluble  in  alcohol.  One  of  the  most 
commonly  employed  salts  of  lithium.  Systemic  Antacid. 
Average  Dose:  8  grains  (0.5  Gm.). 

Lithium  Citrate,  Squibb  bottle,  %  Ib.        ;  oz. 

Lithii  Cilras.  LisCgHoOy^I-^O.  White,  odorless  powder; 
slightly  deliquescent;  cooling,  faintly  alkaline  taste.  1  Gm. 
dissolves  in  1.4  mils  (Cc.)  water;  almost  insoluble  in  alcohol 
or  ether.  Systemic  Alkali,  Diuretic.  Average  Dose :  8  grains 
(0.5  Gm.). 

Lithium  Citrate,  Granular  Effervescent,  Squibb 

bottle,  Ib.          ;  4-oz.  bottles,  per  doz. 

Sal  Lithii  Cilralis  Effervescent,  N.  F.  Dropped  from  U.  S.  P. 
5  percent,  lithium  citrate.  Average  Dose:  120  grains  (8  Gm.). 

Lithium  Glycerophosphate,  Squibb  bottle,  oz. 

C3H-O3PO(OLi)o.  White  water-soluble  powder.  Used 
as  Nervine,  chiefly  in  gout  with  nervous  debility.  Dose : 
3  to  10  grains  (0.2  to  0.65  Gm.).  Avoid  hot  solvents.  Aque- 
ous solutions  do  not  keep  well;  1  minim  chloroform  to  each 
fluidounce  retards  deterioration. 


The  prices  of  the  Squibb  Products  are  in  all  instances  as  low  as 
the  quality  and  quantity  of  ingredients  and  the  expense  of  man- 
ufacture allow.  They  inchjde  containers,  packing  and  boxing.  When 
ordering  or  prescribing  medicinal  products,  specify  SQUIBB'S. 


148       SQUIBB'S  MATERIA  MEDICA 

Lithium  Salicylate,  Squibb  bottle,  \\  lb.         ;  oz. 

Lithii  Salic\>la$.  N.  F.  Dropped  from  U.  S.  P.  LrC7H5O3. 
White  or  grayish-white,  odorless,  sweetish  powder.  Very  solu- 
ble in  water  or  alcohol.  Antirheumatic,  Intestinal  Antiseptic. 
Average  Dose:  15  grains  (I  Gm.). 

Lithium  Tart  rate,  Squibb  bottle,  oz. 

LiaC-iH-iOe.HoO.  White,  crystalline  powder.  Soluble  in 
water.  Dose:  5  to  15  grains  (0.3  to  1  Gm.). 

Litmus  Paper,  Squibb        Blue,  Red  or  Neutral. 

*  strips,  100  in  vial,          ;  box  of  10  vials, 
sheets,  2  in  tube, 

Liver  of  Sulphur.        See  Potassa  Sulphurated. 

®  Lobelia,  Squibb 

Ground  for  Percolation  tin,  lb. 

Lobelia;  Indian  Tobacco.  Dried  leaves  and  flowering  tops  of 
Lobelia  inflala  (Fam.  Lobeliacece) .  Antispasmodic,  Ex- 
pectorant; mainly  in  pectoral  affections.  Average  Dose:  2'/2 
grains  (0.15  Gm.).  (See  also  Fluidextract;  Tincture.) 

LOGWOOD.     See  Hematoxylon. 

LOTION  AMMONIATED  CAMPHOR. 

Lotio  Ammoniacalis  Camphoraia,  N.  F.;  Aqua  Sedativa, 
N.  F.  III.  Each  1000  mils  (Cc.)  contains  60  Gm.  sodium 
chloride,  60  mils  ammonia'  water,  10  mils  spirit  camphor,  with 
water.  Topical  Anodyne  and  Sedative.  Shake  well  before 
dispensing. 

LOTION,  BLACK. 

Lolio  Nigra,  N.  F.;  Black  Wash.  Each  1000  mils  (Cc.) 
contains  8.75  Gm.  calomel,  1 5  mils  water,  lime  water  q.  s. 
Antiseptic,  Cicatrizant,  Parasiticide.  Shake  well  before  dis- 
pensing. 

LOTION  LEAD  AND  OPIUM. 

Lotio  Plumbi  el  Opii,  N.  F.  Each  1000  mils  (Cc.)  contains 
1 7.5  Gm.  lead  acetate,  35  mils  tincture  opium,  water  q.  s. 
Antiphlogistic.  Shake  well  before  dispensing. 

LOTION,  YELLOW. 

Lolio  Flava,  N.  F.;  Yellow  Wash.  Each  1000  mils  (Cc.) 
contains  3  Gm.  corrosive  sublimate,  35  mils  water,  lime  water 
q.  s.  Topical  Antiluetic,  Vulnerary.  Shake  well  before  dis- 
pensing. 

LUGOL'S  SOLUTION.     See    Solution    Iodine    Compound. 
Lunar  Caustic.         See  Silver   Nitrate   Moulded. 


SQUIBB'S  MATERIA  MEDICA        149 

LuPULIN. 

Lupulinum,  N.  F.  Dropped  from  U.  S.  P.  Glandular 
trichomes  separated  from  strobiles  of  Humulus  Lupidus  (Hops). 
Granular,  brownish-yellow  to  brown  powder,  odor  and  taste 
of  hops.  Yields  not  less  than  60  percent,  of  ether-soluble  mat- 
ter. Bitter  Tonic,  asserted  Antaphrodisiac.  Average  Dose : 
8  grains  (0.5  Gm.). 

LYCETOL. 

Dimethylpiperazine  Tartrate.  White,  odorless  powder.  Sol- 
uble in  water.  Diuretic,  Uric-acid  Solvent.  Dose:  15  to  30 
grains  (I  to  2  Gm.),  in  carbonated  water. 

LYCOPODIUM. 

Lpcopoc/j'um.  Spores  of  Lycopodium  clavatum  (Fam>  Lpco- 
podiacece).  Fine,  light-yellow,  very  mobile,  odorless,  taste- 
less powder.  Absorbent  Dusting-powder;  in  intertrigo,  etc. 
Also  used  pharmaceutically  and  technically. 

Mace  Powdered,  Squibb  tin,  Ib. 

sprinkler- top  tins,  for  table  use,  4  oz.,  per  doz. 

2  oz.,  per  doz. 

1  oz.,  per  doz. 

Macts,  N.  F.  Being  part  of  covering  of  nutmeg,  it  possesses 
similar  properties.  Yellowish-red;  strong  odor  and  taste;  con- 
tains 7  to  9  percent,  volatile  oil.  Condiment,  Aromatic,  Car- 
minative. Average  Dose:  8  grains  (0.5  Gm.). 

MACROTYS.     See   Cimicifuga. 

Magma  Bismuth.     See  Bismuth  Magma. 

MAGMA  FERRIC  HYDROXIDE. 

Magma  Ferri  Hydroxidi,  N.  F.;  Ferric  Hydroxide,  U.  S.  P. 
VHIth  Rev.  Freshly  prepared,  brownish-red  magma;  insoluble 
in  water.  For  chemical  or  pharmaceutical  use. 

Magma  Magnesia.     See  Magnesia  Magma. 
Magnesia   Alba.         See    Magnesium   Carbonate. 

Magnesia  Calcined,  Heavy,  Squibb 

tin.lb.          ;   %  Ib. 

Magnesii  Oxidum  Pond'erosum ;  Ponderous  Magnesia.  MgO. 
A  special,  medicinal  quality;  not  the  regular  market  article, 
Action  and  dose  as  of  following. 


If  difficulty  is  experienced  in  procuring  any  Squibb  product, 
in  the  original  packages  here  listed,  please  notify  us;  we 
shall  see  that  your  wants  are  met  promptly  and  satisfactorily. 


150        SQUIBB'S  MATERIA  MEDICA 

0  Magnesia  Calcined,  Light,  Squibb 

tin,  Ib.         ;  14  Ib. 

Magnesii  Oxidum;  Magnesia;  Light  Magnesia;  Magnesia  Usta, 
MgO.  A  special  medicinal  quality;  not  the  regular  market 
article.  Prepared  by  thorough  ignition  of  light  carbonate. 
Almost  insoluble  in  water;  insoluble  in  alcohol.  White,  very 
bulky,  fine,  odorless  powder;  earthy  taste.  Absorbent  dusting 
powder;  Antacid,  Laxative.  Average  Dose:  30  grains  (2 
Cm.)  ;  small  doses  are  antacid,  large  ones  laxative. 

Magnesia  Magma,  Squibb  bottle,  pint,         ;  J/2  pint 

Magma  Magnesias;  Milk  of  Magnesia.  Completely  hydrated 
magnesium  hydroxide  in  aqueous  suspension.  Yields  6.5  to  7.5 
Mg(HO)2l  equivalent  on  average  to  32  grains  per  fluid- 
ounce.  Antacid,  in  conditions  arising  from  gastric  hyperacidity 
and  in  milk  modification  for  infant  feeding;  Neutralizing  Denti- 
frice; Vehicle  for  salicylates,  iodides,  etc.  Average  Dose: 
2J/2  fluidrachms  (10  mils  [Cc.]). 

Magnesia  Usta.        See  Magnesia  Calcined,  Light. 

0  Magnesium  Carbonate,  Squibb  carton,  Ib. 

Magnesii  Carbonas;  Light  Magnesium  Carbonate;  Magnesia 
Alba.  (MgCO3)4.Mg(OH)2.5H2O.  A  specially  repurified, 
medicinal  quality;  not  regular  market  article,  which  is  vastly 
less  costly.  Yields  upon  ignition  not  less  than  39.2  percent, 
magnesium  oxide.  Very  light,  white  powder.  Odorless; 
slightly  earthy  taste.  Practically  insoluble  in  water;  insolubL 
in  alcohol.  Dusting  powder;  Antacid,  Laxative.  Average 
Dose :  45  grains  (3  Gm.)  ;  large  doses  are  laxative. 

MAGNESIUM  CHLORIDE. 

Magnesii  Chloridum,  N.  F.  MgClo.6HoO.  Colorless,  bitter, 
deliquescent  crystals.  I  Gm.  dissolves  in  about  0.6  mil  (Cc.) 
water;  readily  soluble  in  alcohol.  Saline  Cathartic.  Average 
Dose:  4  drachms  (16  Gm.). 

Magnesium  Chloride  Reagent.         See  Reagenfs  (Part  IV). 

Magnesium  Citrate,  Granular  Effervescent,  Squibb 

bottle,  Ib.          ;  4-oz.  bottles,  per  doz. 

Kach  drachm  contains  about  10  grains  anhydrous  magnesium 
citrate.  Mild  Saline  Laxative.  Dose:  120  grains  (8  Gm.). 

Magnesium  Qlycerophosphate,  Squibb  bottle,  oz. 

MgOo.C.sHyOsPO.  White  powder.  Sparingly  soluble  in 
water;  soluble  in  dilute  acids.  Employed  in  neurasthenia, 
rickets,  difficult  dentition,  etc.  Dose:  3  to  6  grains  (0.2  to  0.4 
Gm.).  I  Is  solutions  do  not  keep  well;  1  minim  chloroform  to 
fluidounce  is  said  to  retard  deterioration  very,  materially. 

Magnesium  Hypophosphite,  Squibb 

bottle,          ;   1/4  Ib.          ;   oz. 

Mg(H2PO2)o.6H2O.  White  crystals.  Soluble  in  water. 
Used  as  Tonic.  Dose:  3  to  10  grains  (0.2  to  0.65  Gm.). 
Care  should  be  observed  in  dispensing  this  salt,  as  explosion  is 
liable  to  occur  when  triturated  or-  heated  with  nitrates,  chlorates 
or  other  oxidizing  substances. 


SQUIBB'S  MATERIA  MEDICA        151 

Magnesium  Oxide.       See  Magnesia  Calcined. 

MAGNESIUM  PEROXIDE. 

Magnesium  Dioxide.  MgOo.  White  powder.  Insoluble  in 
water,  but  gradually  decomposed  by  it  into  hydrogen  peroxide 
and  magnesium  hydroxide  and  former  then  decomposed  by  lat- 
ter with  liberation  of  oxygen.  Gastro-intestinal  Antiseptic, 
Antacid.  Dose:  4  to  8  grains  (0.25  to  0.5  Gm.). 

Magnesium  Phosphate,  Squibb 

bottle,  Ib.          ;  |4  lb.          ;  oz. 

Magnesium  Phosphate  Dibasic.  MgHPOi-j-aq.  White,  crys- 
talline powder.  Soluble  in  dilute  acids;  slightly  in  water. 
Alterative,  Antirheumatic.  Dose:  10  to  20  grains  (0.65  to 
1.3  Gm.). 

Magnesium  Salicylate,  Squibb 

tin,  lb.          ;   ^4  lb.         ;    1-oz.  vial, 

Mg(C7H5O3).4HoO.  White,  crystalline  powder,  containing 
about  74  percent,  of  salicylic  acid.  Soluble  in  about  5  parts 
water.  Antirheumatic  and  Antifermentative,  like  Sodium  Sa- 
licylate, but  latterly  recommended  especially  as  an  intestinal 
Antizymotic.  Dose:  5  to  30  grains  (0.3  to  2  Gm.)  three  times 
daily,  between  meals.  (See  also  Tablets  [Part  II].) 

®  Magnesium  Sulphate,  Squibb 

(Granular)  tin,  lb.         ;  ]/2  lb.         ;  |4  lb. 

Magnesii  Sulphas;  Epsom  Salt.  MgSC>4.7HoO.  A  recrys- 
tallized,  distinctive  quality,  almost  free  from  the  bitterness  usu- 
ally found  in  the  regular  market  article.  Repurified  by  recrys- 
tallization,  to  remove  dirt  and  mechanical  impurities  unavoid- 
ably present  in  ordinary  grade  because  of  the  crude  method  of 
its  preparation  on  a  large  scale.  It  is  carefully  put  up  to  pre- 
serve its  cleanly  condition,  and  will  be  found  to  make  a  clear 
solution  wholly  free  from  arsenic  and  heavy  metals.  Small, 
colorless,  odorless,  slowly  efflorescent  granules,  of  cooling,  saline, 
bitter  taste.  1  Gm.  dissolves  in  I  mil  (Cc.)  water;  insoluble  in 
alcohol.  Active  Saline  Cathartic;  latterly  also  used  locally  as 
an  Antiphlogistic  in  erysipelas,  ivy  poisoning  and  cutaneous 
inflammation  in  general,  a  saturated  aqueous  solution  being 
employed  on  compresses  constantly  kept  moist  with  the  lotion; 
also  credited  with  Local  Anesthetic  and  Antitetanic  power 
when  used  by  subarachnoid  injection.  Average  Dose :  240 
grains  (16  Gm.).  Acts  in  j/2  to  1  hour  if  taken  before  break- 
fast; in  2  to  4  hours  if  patient  is  in  bed.  (See  also  Reagents.) 


The  Squibb  products  are  recognized  everywhere  as  the  Quality 
Standard.  They  are  of  uniform  purity  and  strength,  hence 
therapeutically  dependable.  When  ordering  or  prescribing  med- 
icinal products,  you  will  do  well  always  to  specify  SQUIBB'S. 


152        SQUIBB'S  MATERIA  MEDICA 

Magnesium  Sulphate  Exsiccated,  Squibb 

carton,  Ib.          ;  |4  lb. 

The  foregoing  crystalline  magnesium  sulphate  deprived  of  its 
water  of  crystallization.  Action  same  as  preceding  granular 
salt,  but  twice  as  strong.  Used  also  as  Reagent.  Average 
Dose:  120  grains  (8  Cm.). 

Magnesium   Sulphate,    Granular    Effervescent,    Squibb 

bottle,  lb.          ;  4-oz.  bottles,  per  doz. 

Contains  50  percent,  magnesium  sulphate.  Dose:  V0  t°  I  oz« 
tr.  (16  to  32  Gm.). 

Magnesium  and  Ammonium  Phosphate,  Squibb 

bottle,  lb.          ;   |4  lb.          ;   oz. 

Mg(NH4)PC>4.6HoO.  White,  odorless,  tasteless  powder. 
Insoluble  in  ordinary  organic  solvents.  Gastric  Sedative  and 
Protective,  like  bismuth  salts;  also  used  in  gout.  Dose:  10  to 
30  grains  (0.65  to  2  Cm.). 

0  MALE  FERN.    See  Aspidium. 

MALLOW  LEAVES. 

Mahee  Folia,  N.  F.  Dried  leaves  of  Malva  syhestris  and  M. 
rolundifolia.  (Fam.  Ma/vacece).  Inodorous;  mucilaginous, 
bland  taste.  Demulcent  "herb  tea." 

MALT. 

Maltum.  Grain  of  HorJeum  salivum  (Fam.  Cramineai), 
partly  germinated  artificially,  then  dried.  Yellow  or  amber 
grains;  agreeable  odor;  sweet  taste.  1  Gm.  converts  5  Gm. 
potato  starch  into  sugars.  (See  also  Extract.) 

0  MANDRAKE.     See  Podophyllum. 

Manganese  Citrate  Soluble,  Squibb  bottle,  oz. 

Mangani  Citras  Solubilis,  N.  F.  Pinkish,  glistening,  odorless, 
slightly  hygroscopic  scales;  containing  about  13.5  percent,  man- 
ganese. 1  Gm.  dissolves  slowly  in  about  4  mils  (Cc.)  water; 
nearly  insoluble  in  alcohol.  Hematinic,  but  designed  especially 
for  use  in'preparing  Solution  Iron  Peptonate  and  Manganese, 

Manganese  Dioxide  Precipitated,  Squibb  oz. 

Mangani  Dioxldum  Pracipitatum ;  Manganese  Peroxide  or 
Hyperoxide;  Black  Oxide  of  Manganese.  Not  less  than  80 
percent.  MnOo,  with  small  amounts  of  other  oxides  of  man- 
ganese. Great  care  is  observed  in  its  manufacture,  and  it  is 
proven  to  conform  in  all  respects  to  U.  S.  P.  requirements. 
Heavy,  fine,  black,  odorless,  tasteless,  insoluble  powder.  Altera- 
tive and  Emmenagogue  internally;  Dermic  (10  to  25  percent, 
ointment)  externally.  Average  Dose:  4  grains  (0.25  Gm.). 
(See  also  Reagents  [Part  IV];  Tablets  [Part  II].) 


SQUIBB'S  MATERIA  MEDICA        153 

Manganese  (iiycerophosphate,  Squibb  bottle,  oz. 

Mangani  Glycerophosphas  Solubilis,  N.  F.  Yellowish  to 
brownish  or  pinkish  powder.  Contains  70  to  75  percent. 
MnCsHyPOg,  with  citric  acid.  I  Gm.  dissolves  in  about  4 
mils  (Cc.)  water.  Used  as  Nerve  Tonic;  in  neurasthenia,  con- 
valescence, etc.  Average  Dose:  3  grains  (0.2  Gm.).  Its 
solutions  do  not  keep  well;  1  minim  chloroform  to  each  fluid- 
ounce  retards  their  deterioration. 

Manganese  Hypophosphite,  Squibb 

bottle,  Ib.          ;  14  lb.  .      ;  oz. 

Mangani  Hypophosphis,  N.  F.  Mn(PH2O2)2-H2O.  Pink, 
odorless,  nearly  tasteless  salt.  Freely  soluble  in  water;  almost 
insoluble  in  alcohol.  Hematinic.  Average  Dose :  3  grains 
(0.2  Gm.). 

Manganese  Oxide,  Black.        See  Manganese  Dioxide. 

Manganese  Sulphate,  Squibb 

bottle,  Ib.          ;  J4  Ib.          ;  oz. 

Mangani  Sulphas,  N.  F.;  Manganous  Sulphate.  Dropped 
from  U.  S.  P.  MnSO4.4H9O.  Colorless  or  pal«-pink,  trans- 
lucent, slightly  efflorescent,  odorless,  bitter-astringent  crystals. 
1  Gm.  dissolves  in  about  1  mil  (Cc.)  water;  insoluble  in  alco- 
hol. Used  as  Hematinic  and  Alterative  internally;  Dis- 
cutient  externally  (10  to  20  percent,  ointment),  in  stiff  joints 
from  gout,  rheumatism,  etc.  Average  Dose:  3  grains  (0.2  Gm.). 
(See  also  Reagents  [Part  IV].) 

MANNA. 

Manna.  Dried  saccharine  exudation  of  Frtixinus  Ornus  (Fam. 
O/eaceffl).  Yellowish-white,  irregular,  elongated  pieces  or 
masses;  slight,  characteristic  odor;  sweet,  slightly  acrid  taste. 
Mild  Cathartic,  Sweetener;  usually  prescribed  with  other  purga- 
tives, and  mostly  for  children.  Average  Dose:  4  drachms  (16 
Gm.). 

Marigold.     See  Calendula. 

Marsh  Mallow  Powdered.      See  Althaea  Powdered. 

Mass,  Blue.         See  Mass  Mercury. 

MASS  COPAIBA. 

Massa  Copaibce,  N.  F.;  Solidified  Copaiba.  94  percent, 
copaiba,  massed  with  6  percent,  magnesium  oxide.  Antica- 
tarrhal,  Antiseptic,  Cicatrizant.  Average  Dose:  15  grains  (1 
Gm.). 


Since  we  make  only  one  quality  of  each  product,  that  best 
suited  to  the  purposes  intended,  the  specification  "Squibb's" 
is  not  open  to  various  interpretations,  but  has  a  plain,  positive 
meaning.  When  ordering  or  prescribing,  specify  SQUIBB'S- 


154       SQUIBB'S  MATERIA  MEDICA 

0  Mass  Ferrous  Carbonate,  Squibb 

jar,  Ib.          ;  %  Ib. 

Massa  Ferri  Carbonalis;  Vallet's  Mass.  Containing  not  less 
than  35  percent.  FeCOs.  Hematinic.  Average  Dose:  4 
grains  (0.25  Cm.). 

®  Mass  Mercury,  Squibb 

*Pilular  jar,  Ib.         ;  Y4  Ib. 

Powdered  bottle,  Ib.         ;  J4  Ib. 

Blue  Mass;  Blue  Pill;  Mercury  Pill.  Made  by  a  special 
-  formula  yielding  a  product  superior  to  U.  S.  P.  Massa  Hydrar- 
gyri.  Contains  33  percent,  mercury,  as  officially  demanded, 
but  the  althaea  and  glycerin  are  replaced  by  sugar  which 
serves  the  purpose  better.  A  specially  devised  shaker  sub- 
divides the  mercury  until  the  globules  are  invisible  under  a 
lens  magnifying  ten  diameters.  Mercury  mass  has  a  tendency 
to  harden  on  the  surface  by  age,  which,  however,  does  not 
affect  its  efficiency.  A  small  quantity  of  glycerin  is  placed 
on  the  surface  to  minimize  this  condition.  If  not  too  old  the 
mass  immediately  under  the  surface  will  be  found  of  the 
normal  consistency.  Cathartic,  Antiluetic.  Average  Dose:  4 
grains  (0.25  Gm.),  as  pills  or  tablets.  (See  also  Tablets  [Part 
II].) 

Mass,   Vallet's.        See  Mass  Ferrous  Carbonate. 

MASTIC. 

Mastiche,  N.  F.  Concrete  resinous  exudation  from  Pistacia 
Leniiscus  (Fam.  Anacardiacece) .  Pale-yellow  or  greenish- 
yellow,  transparent,  brittle  tears;  slight,  balsamic  odor;  mild, 
terebinthinate  taste.  Carminative,  Corrigent.  Average  Dose: 
30  grains  (2  Gm.). 

MATICO. 

Matico,  N.  F.  Dropped  from  U.  S.  P.  Dried  leaves  of  Piper 
angusti folium  (Fam.  Piperaceae).  Genito-urinary  Stimulant, 
similar  to  buchu.  Average  Dose:  I  drachm  (4  Gm.). 

Matricaria,  Squibb  tin,  Ib. 

M air  tear  ia;  German  Chamomile.  Dried  flower-heads  of  Mat- 
ricaria Chamomilla  (Fam.  Composites).  Carefully  differentiated 
from  English  chamomile  and  other  allied  species.  Popularly 
used  as  a  Bitter  and  Aromatic  tea  and  poultice.  Average  Dose: 
240  grains  (16  Gm.) 

MAY  APPLE.     See  Podophyllum. 
MEADOW  SAFFRON.     See  Colchicum. 
MEDINAL.     Brand  of   Barbital-Sodium. 


SQUIBB'S  MATERIA  MEDICA        155 

MELILOT. 

Melilotus,  N.  F. ;  Yellow  Sweet  Clover.  Dried  leaves  and 
flowering  tops  of  Melilotus  officinalis  (Fam.  Leguminosai) . 
Tonka-like  odor;  sweetish,  slightly  pungent  taste.  Emollient; 
also  used  as  Stimulant  and  Antispasmodic,  in  neuralgia. 

®  Menthol,  Squibb  bottle,  oz. 

Menthol;  Peppermint  Camphor.  CioHigOH.  A  secondary  al- 
cohol from  oil  peppermint.  Colorless  needles;  strong  peppermint 
odor;  warm  aromatic  taste,  followed  by  sensation  of  cold 
when  air  is  drawn  into  mouth.  Very  slightly  soluble  in  water 
or  glycerin;  freely  soluble  in  alcohol,  ether.^chloroform,  or 
fixed  oils.  It  liquefies  when  triturated  with  about  an  equal 
weight  of  camphor,  thymol,  chloral  hydrate,  phenol,  betanaph- 
thol  or  resorcinol.  Counter-irritant,  Anodyne,  Anesthetic,  ex- 
ternally, in  headache,  toothache,  skin  diseases,  coryza,  etc.; 
Carminative,  internally,  in  vomiting,  colic,  etc.  Average  Dose : 
1  grain  (0.065  Gm.). 

Menthol  Camphorated,  Squibb  1-oz.  vial 

Menthol  Camphoratum,  N.  F.;  Campho-Menthol.  Lique- 
fied mixture  of  equal  parts  camphor  and  menthol  with  5  percent, 
alcohol.  Local  Anodyne,  Counter-irritant. 

MENYANTHES. 

Menyanthes,  N.  F.;  Buckbean;  Marsh  Trefoil.  Dried  leaves 
of  Menyanthes  trifoliafa  (Fam.  Centianacece).  Bitter. 
Average  Dose:  15  grains  (1  Gm.). 

MERCUROL. 

Mercury  Nucleinate.  Brownish-white  powder;  10  percent, 
mercury.  Soluble  in  water;  insoluble  in  alcohol.  Astringent, 
Antipyic,  Antisyphilitic.  Applied  in  J/2  to  5  percent,  solution. 
Dose:  Y2  to  2  grains  (0.03  to  0.13  Gm.). 

0  Mercury  Repurified,  Squibb  stone  bottle,  Ib. 

Hydrargyrum;  Quicksilver.  Hg.  Sp.  gr.  13.5.  A  very  pure 
grade,  practically  free  from  foreign  metals.  Eligible  for  dental 
use  and  for  all  other  uses  demanding  a  highly  pure  product. 
(See  also  Reagents  [Part  IV].) 

©Mercury  Ammoniated,  Squibb 

(Powdered)  bottle,  Ib.         ;  Y4  Ib. 

Hydrargyrum  Ammoniatum;  White  Precipitate;  Mercury  and 
Ammonium  Chloride;  Sal  Alembroth.  HgNHoCl.  White, 
amorphous,  odorless  powder;  earthy,  afterwards  styptic,  metallic 
taste.  Insoluble  in  water  or  alcohol.  Antiparasitic  Dermic, 
in  1  to  10  percent,  ointment.  (See  also  Ointment.) 


The  founder  of  the  House  of  Squibb,  Dr.  Edward  R.  Squibb, 
not  only  had  high  ideals,  but  lived  and  labored  for  them;  and, 
in  the  words  of  William  Miller  Bartlett,  "the  House  of  Squibb 
stands  today  as  a  living  monument  to  the  honor,  integrity,  zeal 
and  devotion  of  its  founder." 


156        SQUIBB'S  MATERIA  MEDICA 

Mercury  Bichloride  or  Perchloride.     See  Mercury  Chlo- 
ride Corrosive. 

Mercury    Biniodide.        See  Mercury  Iodide  Red. 

Mercury  Bromide  (Mercuric)  Reagent. 

See  Reagents  (Part  IV). 

0  Mercury  Chloride  Corrosive,  Squibb 

*  Powdered  or  Granular         bottle,  Ib.  ;  14  Ib. 

Hydrargyri  Chloridum  Corrosivum;  Corrosive  Sublimate; 
Mercuric  Chloride;  Mercury  Bichloride  or  Perchloride. 
HgClo.  Heavy,  colorless,  odorless  granules,  or  white  powder; 
acrid,  persistent  metallic  taste.  1  Gm.  dissolves  in  13.5  mils 
(Cc.)  water,  3.8  alcohol,  12  glycerin,  22  ether.  Antiseptic, 
Alterative,  Antiluetic;  wash  for  wounds,  etc.,  in  syphilis,  skin 
diseases,  chronic  rheumatism,  etc.  Also  Reagent.  Average 
Dose:  1/20  grain  (0.003  Gm.).  Incompatible  with  alkalies, 
alkaloidal  salts;  with  copper,  iron  and  zinc  salts,  hypo- 
phosphites;  infusions  cinchona,  calumba,  oak  bark  or  senna. 
Antidotes:  white  of  egg,  or  flour  stirred  in  mflk;  emetics;  Dr. 
Fantus's  antidote  (6  grains  sodium  hypophosphite  with  4  grains 
sodium  acetate,  or  1 5  grains  sodium  hypophosphite  with  2*/2 
fluidrachms  water  and  1J/4  fluidrachms  solution  hydrogen  perox- 
ide. If  amount  of  poison  taken  is  known  Dr.  F.  gives  10  times 
as  much  sodium  hypophosphite,  followed  at  once  by  copious 
gastric  lavage  with  3  percent,  solution  sodium  bicarbonate  to 
which  may  be  added  8  grains  sodium  hypophosphite.  The  en- 
tire procedure  is  repeated  every  8  hours  until  gastric  contents 
are  free  from  mercury  by  Vogel's  test)  ;  castor  oil.  (See  also 
Tablets  [Part  II];  Reagents  [Part  IV].) 

0  Mercury  Chloride  Mild,  Squibb  bottle,  Ib.  ;  |4  Ib. 
Hydrargyri  Chloridum  Mite;  Calomel;  Mercurous  Chloride; 
Mercury  Subchloride  or  Protochloride.  HgCI.  Odorless, 
tasteless,  impalpable  powder.  Insoluble  in  ordinary  solvents. 
Cholagogue  Cathartic,  Antisyphilitic,  Alterative,  Intestinal  Anti- 
septic; also  Reagent.  Average  Dose:  laxative,  2\/2  grains 
(0.15  Gm.);  alterative,  etc.,  %  grain  (0.015  Gm.).  Incom- 
patible with  iodine,  soluble  iodides  and  bromides,  alkalies,  al- 
kaloidal salts,  etc.  (See  also  Tablets  Calomel  [Part  II]  ; 
Reagents  [Part  IV].) 

0  Mercury  Iodide  Red,  Squibb 

bottle,  Ib.          ;  %  Ib.         ;  oz. 

HyJrargyri  lodidum  Rubrum ;  Mercury  Biniodide;  Precipi- 
tated Mercuric  Iodide.  Hgls-  Scarlet-red,  amorphous,  odor- 
less, nearly  tasteless  powder.  1  Gm.  dissolves  in  115  mils 
(Cc.)  alcohol,  .910  chloroform,  120  ether;  also  soluble 
in  solutions  of  soluble  iodides,  mercuric  chloride  and  sodium 
thiosulphate;  almost  insoluble  in  water  or  glycerin.  Anti- 
syphilitic,  Alterative;  in  syphilis,  scrofula,  obstinate  skin  dis- 
eases, etc.  Also  Reagent.  Incompatible  with  alkalies,  alkali 
carbonates,  alkaloidal  salts,  etc.  Average  Dose :  VOQ  grain 
(0.003  Gm.).  (See  also  Tablets  [Part  II].) 


SQUIBB'S  MATERIA  MEDICA        157 

©  Mercury  Iodide  Yellow,  Squibb 

bottle,  Ib.          ;  '/^  Ib.          ;  oz. 

Hydrargyri  lodidum  Flavum;  Yellow  Mercurous  Iodide;  Mer- 
cury Protiodide.  Hgl.  Yellow,  odorless  powder.  Practically 
insoluble  in  water;  insoluble  in  alcohol  or  ether.  Antisyphilitic, 
Alterative.  Average  Dose:  J/&  grain  (0.01  Gm.).  Incompatible 
with  alkali  iodides,  bromides  and  chlorides;  with  oxidizing 
agents,  etc.  (See  also  Tablets  [Part  II].) 

Mercury  Mass.         See  Mass  Mercury. 
MERCURY  NUCLEINATE.    See  Mercurol. 
Mercury  Oleate.        See  Oleate  Mercury. 

Mercury  Oxide  Red,  Squibb 

bottle,  Ib.         ;  %  Ib.         ;  oz. 

Hydrargyri  Oxidum  Rubrum;  Red  Mercuric  Oxide;  Red  Pre- 
cipitate. HgO.  Heavy,  orange-red,  crystalline  scales  or  pow- 
der; odorless;  slight  metallic  taste.  Almost  insoluble  in  water; 
insoluble  in  alcohol.  Used  only  externally,  in  j/2  to  10  per- 
cent, ointment,  as  Parasiticide  and  Antiluetic.  (See  also  Re- 
agents [Part  IV].) 

©  Mercury  Oxide  Yellow,  Squibb 

bottle,  Ib.          ;  %  Ib.          ;  oz. 

Hydrargyri  Oxidum  Flavum;  Yellow  Precipitate.  HgO. 
Orange-yellow,  amorphous,  heavy,  odorless,  impalpable  pow- 
der; slightly  metallic  taste.  Almost  insoluble  in  water;  in- 
soluble in  alcohol.  Employed  in  0.5  to  10  percent,  ointment 
as  Parasiticide,  Cicatrizant,  Antipyic;  in  ophthalmia,  ring- 
worm, pediculi,  chancre,  etc.  (See  also  Ointment.) 

Mercury  Protiodide.         See  Mercury  Iodide  Yellow. 
Mercury  Protochloride.       See  Mercury  Chloride  Mild. 

©   Mercury  Salicylate,   Squibb  bottle,  oz. 

Hydrargyri  Sallcylas;  Mercuric  Salicylate.  White  or  pinkish- 
white,  odorless,  tasteless  powder ;  54  to  59.5  per  cent.  Hg. 
Nearly  insoluble  in  water  or  alcohol ;  soluble  in  solutions  of 
fixed  alkalies  or  their  carbonates.  Antiluetic,  Gonococcicide 
(1:300  suspension),  Antiseptic  (10  percent,  powder  or  oint- 
ment). Average  Dose:  VlO  grain  (0.004  Gm.);  by  intra- 
muscular injection,  1  grain  (0.065  Gm.)  in  suspension  every 
fourth  to  second  day.  Incompatible  with  iodides.  (See  also 
Ampuls.) 


The  Squibb  Ideals  have  taken  concrete  form  in  the  Squibb 
Products;  these  are  universally  recognized  as  standards  of 
uniform  Purity  and  Efficacy,  that  is,  general  Excellence  and 
Reliability.  Specify  SQUIBB'S  when  prescribing  or  ordering. 


158        SQUIBB'S  MATERIA  MEDICA 

Mercury  Subchloride.  See  Mercury  Chloride,  Mild, 
Mercury  Subsulphate  Yellow,  Squibb  bottle,  oz. 

Hydrargyri  Subsulphas  Flavus,  U.  S.  P.  1890;  Turpeth  Min- 
eral; Basic  Mecuric  Sulphate.  HgSC>4.2HgO.  Heavy,  yel- 
low, odorless,  almost  tasteless  powder.  Soluble  in  about  2,000 
parts  cold  water,  25  hot  water.  Antiluetic,  chiefly  subcutane- 
Emetic;  in  syphilis,  croup,  etc.  Dose:  alterative  J/^  *°  !/2  gram 
(0.015  to  003  Gm.);  emetic  (in  children),  2  to  3  grains  (0.13 
to  0.2  Gm.). 

MERCURY  SUCCINIMIDE. 

Hg[(CH;>.CO)oN]2.  White  powder.  Soluble  in  about  75 
parts  cold  water,  25  hot  water.  Antiluetit,  chiefly  subcutane- 
ously;  said  to  be  non-irritating.  Dose:  '/5  to  2/£  grain  (0.012 
to  0.025  Gm.)  daily.  (See  also  Tablets,  Hypodermic  [Part 
II].) 

Mercury  Sulphide  Red,  Squibb  bottle,  oz. 

Vermilion;  Artificial  Cinnabar.  HgS.  Bright-scarlet  powder. 
Insoluble  in  water,  alcohol  or  hydrochloric  acid.  Used  mostly 
technically;  sometimes  by  fumigation  in  syphilis,  30  grains  (2 
Gm.)  on  red-hot  iron  and  fuirres  inhaled. 

Mercury  Tannate,  Squibb  bottle,  oz. 

Mercurous  Tannate.  2Hg2.3(Ci4H9Oo).OH.  Greenish-gray 
powder;  50  percent,  mercury.  Insoluble  in  ordinary  solvents. 
Antiluetic.  Dose:  1  to  2  grains  (0.065  to  0.13  Gm.).  (See 
also  Tablets  [Part  II]). 

Mercury  and  Ammonium  Chloride.    See  Mercury  Ammoni- 
ated. 

0  Mercury  with  Chalk,  Squibb  bottle,  %  Ib.  ;  oz. 
Hydrargyrum  cum  Creta;  Gray  pow-der.  38  percent,  mercury, 
incorporated  in  a  state  of  very  minute  subdivision  with  57  per- 
cent precipitated  chalk.  We  use  latter  instead  of  prepared 
chalk  (officially  prescribed),  because  it  yields  a  better  product. 
Light  gray,  rather  damp  powder;  odorless,  slightly  sweetish 
taste.  Intestinal  Antiseptic,  Mild  Cathartic,  Antiluetic.  Aver- 
age Dose:  4  grains  (0.25  Gm.).  (See  also  Tablets  [Part 
II].) 

MERGAL. 

Mixture  of  Mercuric  Cholate  1  part,  and  Tannin  Albuminate 
2  parts,  in  capsule  form.  ^4  grain  mercuric  cholate  equals  in 
mercury  content  "/22  grain  corrosive  sublimate.  Insoluble  in 
water,  readily  soluble  in  digestive  fluids.  Antiluetic.  Dose: 
2K2  to  5  grains  (0.15  to  0.3  Gm.). 

MESOTAN. 

Ericin;  Methyloxymethyl  Salicylate.  Yellowish,  faintly  aro- 
matic, oily  liquid,  sp.  gr.  1 .2.  Soluble  freely  in  oils,  alcohol, 
ether,  chloroform;  sparingly  in  water.  Local  Antirheumatic 
and  Anodyne.  Applied  with  equal  volume  olive  oil. 


SQUIBB'S  MATERIA  MEDICA        159 

Methyl  Acetate,  Squibb  bottle,  Ib.         ;  %  Ib. 

CsHijOo.  Colorless,  fragrant  liquid;  sp.  gr.  about  0.960.  Mis- 
cible  with  alcohol  or  ether',  moderately  soluble  in  water.  Used 
technically. 

METHYL  AMINOXYBENZOATE.    See  Orthoform. 
Methylbenzoylecgonine.      See  Cocaine. 

®  Methyl   Salicylate,   Squibb          bottle,  Ib.         ;  %  Ib. 

Methylis  Salicylas;  Synthetic  (Artificial)  Oil  Wintergreen. 
CHaCTHaOs.  Practically  identical  with  oils  gaultheria  and 
birch.  Colorless,  yellowish  or  reddish  liquid;  wintergreen  odor; 
sweetish,  aromatic  taste.  Sp.  gr.  1.180  to  1.185.  Soluble 
freely  in  alcohol,  ether,  chloroform;  sparingly  in  water.  Anti- 
rheumatic,  Antipyretic;  Flavoring.  Average  Dose:  12  minims 
(0.75  mil  [Cc.]). 

Methylene  Blue,  Medicinal.     See  Methylthkmine  Chloride. 
Methylmorphine.        See  Codeine. 

Methylthionine  Chloride,  Squibb  bottle,  oz. 

M eihyllh'ionince  Chloridum;  Methylene  Blue  Medicinal. 
CieHisNgCISJHoO.  Aniline  derivative,  free  from  arsenic, 
commercial  dye  and  mineral  impurities.  Specially  prepared  for 
medicinal  use.  Ordinary  methylene  blue  contains  zinc  chloride 
and  arsenic,  and  is  not  eligible  for  medicinal  use.  Dark- 
green,  crystalline  powder,  or  crystals  of  bronze-like  lustre. 
Readily  soluble  in  water  or  alcohol;  less  freely  in  chloroform. 
Urinary  Antiseptic,  Antiperiodic,  Anodyne;  in  malaria, 
gonorrhea,  cystitis,  carcinoma,  etc.  Also  Reagent.  Average 
Dose:  2'/->  grains  (0.15  Gm.) ;  by  injection,  1  grain  (0.065 
Gm.).  Urine  becomes  greenish-blue  during  use  of  this  drug. 
Incompatible  with  potassium  iodide  and  reducing  agents. 

MEZEREUM. 

Mezereum;  Mezereon.  Dried  bark  of  Daphne  Mezereum,  D. 
GniJIum  or  D.  Laureola  (Fam.  Thymeleacece).  Antiquated 
Antiluetic  and  Vesicant. 

MILK  FERMENTED. 

Lac  Fermenialum,  N.  F.;  Kumyss.  Cow's  milk  fermented 
with  compressed  yeast  and  sugar.  Nutrient.  Average  Dose : 
8  fluidounces  (240  mils  [Cc.]). 

MILK  OF  ALMOND.    See  Emulsion  Almond. 
MILK  OF  ASAFETIDA.     See  Emulsion  Asafetida. 


The  Squibb  Label  on  a  package  is  a  positive  guaranty  for  the 
uniform  Purity  and  Reliability  of  the  product.  We  make  only 
ONE'quality:  the  SQUIBB  quality;  and  our  prices  are  as  low 
as  they  can  be  made  for  that  quality.  Specify  SQUIBB'S. 


160        SQUIBB'S  MATERIA  MEDICA 

Magma  Bismuth.     See  Bismuth  Magma. 
Magma  Magnesia.      See  Magnesia  Magma. 
Milk  of  Bismuth     See  Bismuth  Magma. 
Milk  of  Magnesia.     See  Magnesia  Magma. 
Milk  Of  Sulphur.         See  Sulphur  Precipitated. 

Milk  Sugar.       See  Sugar  of  Milk. 

Mineral  Oil.      See  Liquid  Petrolatum. 
MIXTURE  ALMOND.    See  Emulsion  Almond. 

MIXTURE  AMMONIUM  CHLORIDE. 

Misiura  Ammonii  Chloridi,  N.  F.  Each  fluidounce  contains 
about  1 1  ]/2  grains  each  ammonium  chloride  and  pure  extract 
licorice,  with  water.  Expectorant.  Average  Dose :  2  fluidrachms 
(8  mils  [Cc.]). 

MIXTURE,  ASTRINGENT. 

Mistura  Adstringens,  N.  F.;  Mixture  Astringent  and  Eschar- 
otic;  Villate's  Solution.  Prepared  from  solution  lead  sub- 
acetate,  copper  sulphate,  zinc  sulphate  and  diluted  acetic  acid; 
the  resulting  lead  sulphate  being  removed.  Astringent  (diluted 
with  3  or  4  parts  water)  and  Escharotic  (pure). 

MIXTURE,  BASHAM'S.     See  Solution  Iron  and  Ammonium  Acetate. 
Mixture,  Brown.        See  Mixture  Glycyrrhiza  Compound. 

MIXTURE  CAMPHOR  ACID. 

Mistura  C amphora  Adda,  N.  F.;  Hope's  Mixture.  Each  fluid- 
ounce  contains  8%  minims  nitric  acid,  5^4  minims  tincture 
opium,  with  camphor  water.  Intestinal  Astringent.  Average 
Dose:  2  fluidrachms  (8  mils  [Cc.]). 

MIXTURE  CAMPHOR  AROMATIC. 

Misiura  Camphors  Aromaiica,  N.  F.;  Parrish's  Camphor 
Mixture.  Each  100  mils  (Cc.)  contains  25  mils  compound 
tincture  lavender,  3.5  Gm.  sugar,  camphor  water  q.  s.  Aro- 
matic Carminative.  Average  Dose:  2  fluidrachms  (8  mils). 

fMixTURE  CARMINATIVE. 

Misiura  Carminativa,  N.  F. ;  Dalby's  Carminative.  Each 
fluidounce  contains  30  grains  magnesium  carbonate,  lj/2  grains 
potassium  carbonate,  12  minims  tincture  opium,  J/4  minim  each 
oils  caraway,  fennel  and  peppermint,  with  syrup  and  water. 
Carminative.  Average  Dose:  infants',  8  minims  (0.5  mil). 

MIXTURE  CHALK. 

Mistura  Creta.  Compound  chalk  powder  20  percent.,  cinna- 
mon water  40  vol.  percent.  Antacid,  Antidiarrheal.  Average 
Dose:  4  fluidrachms  (15  mils  [Cc.]). 


SQUIBB'S  MATERIA  MEDICA        161 

Mixture   Chloral  and   Potassium   Bromide   Compound, 
Squibb  pint,          ;  |4  pint 

Mislura  Chloralis  el  Potassii  Bromidi  Composita,  N.  F.  Each 
fluidrachm  contains  about  11%  grains  each  chloral  hydrate  and 
potassium  bromide,  and  j/g  grain  each  extracts  cannabis  and 
hyoscyamus.  Nerve  Sedative,  Hypnotic,  Antispasmodic. 
Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

MIXTURE  CHLOROFORM  AND  CANNABIS  COMPOUND.    See  Mixture 
Chloroform  and  Morphine  Compound. 

f  MIXTURE  CHOLOFORM  AND  MORPHINE  COMPOUND. 

Misiura  Chloroformi  et  Morphines  Composila,  N.  F.;  for- 
merly Mixture  Chloroform  and  Cannabis  Indica  Compound. 
Each  fluidounce  contains  about  60  minims  chloroform,  89 
minims  tincture  cannabis,  12  minims  tincture  capsicum,  15.6 
minims  ether,  and  l'/5  grains  morphine  sulphate.  Analgesic, 
Carminative.  Average  Dose:  30  minims  (2  mils  [Cc.]). 

MIXTURE  COPAIBA. 

Mislura  Copaiba.  N.  F.;  Lafayette  Mixture.  Each  fluid- 
ounce  contains  I  fluidrachm  each  copaiba,  spirit  nitrous  ether 
and  compound  tincture  lavender,  15  minims  solution  potassium 
hydroxide,  with  syrup  and  mucilage  acacia.  Genito-urinary 
Anticatarrhal,  Diuretic.  Average  Dose:  2  fluidrachms  (8  mils). 

MIXTURE  COPAIBA  AND  OPIUM. 

Mistura  Copaiba  el  Opii,  N.  F.;  Chapman's  Mixture.  Each 
100  mils  (Cc.)  contains  25  mils  copaiba,  25  spirit  nitrous 
ether,  6.5  compound  tincture  lavender,  3.2  tincture  opium,  12.5 
mucilage  acacia,  water  q.s.  Used  as  Genito-urinary  Anti- 
catarrhal, Diuretic;  mainly  in  gonorrhea.  Average  Dose:  1 
fluidrachm  (4  mils). 

Mixture,  Diarrhea.        See  Tincture  Opium  Compound. 

Mixture  Glycyrrhiza  Compound,  Squibb  pint, 

Misiura  Glycrrhizce  Composita;  Brown  Mixture;  Licorice  Mix- 
ture. Containing  pure  extract  glycyrrhiza,  acacia,  camphorated 
tincture  opium,  antimony  and  potassium  tartrate  ('/g  gr.  per 
fl.  oz.),  and  spirit  nitrous  ether,  in  syrup  and  water.  Expec- 
torant. Average  Dose:  2J/2  fluidrachms  (10  mils  [Cc.]). 

MIXTURE,  GRIFFITH'S.     See  Mixture  Iron  Compound. 

MIXTURE  GUAIAC. 

Mislura  Cuaiaci,  N.  F.  Contains  12.5  volume  percent,  tinc- 
ture guaiac,  with  honey  and  cinnamon  water.  Alterative  in 
chronic  rheumatism,  gout,  etc.  Average  Dose:  4  fluidrachms 
(16  mils  [Cc.]). 

This  house  supplies  only  one  quality  of  each  product:  that  best 
suited  to  the  purposes  intended.  The  specification  "Squibb's" 
is  not  open  to  various  interpretations;  it  has  a  plain,  posi- 
tive meaning.  Therefore,  when  prescribing,  specify  SQUIBB'S. 
B 


162       SQUIBB'S  MATERIA  MEDICA 

MIXTURE,  HOPE'S.     See  Mixture  Camphor  Acid. 

MIXTURE  IRON  COMPOUND. 

Mi&lura  Ferri  Composita,  N.  F.;  Griffith's  Mixture.  Should 
be  freshly  made  when  wanted.  Contains  nascent  ferrous  car- 
bonate suspended  in  myrrh  emulsion.  Only  the  green  mixture 
should  be  dispensed;  not  when  it  has  become  darker,  reddish- 
brown  in  color.  Hematinic;  in  chronic  skin  diseases,  chlorosis, 
and  other  chronic  conditions  attended  by  anemia.  Average 
Dose:  4  fluidrachms  (16  mils  [Cc.]). 

MIXTURE,  LAFAYETTE.    See  Mixture  Copaiba. 

Mixture  Licorice.       See  Mixture  Glycyrrhiza  Compound. 

MIXTURE  MAGNESIA,  ASAFETIDA  AND  OPIUM. 

Mislura  Magnesia,  Asafcstids  el  Opii,  N.  F.;  Dewees'  Car- 
minative. Each  fluidounce  contains  about  23  grains  mag- 
nesium carbonate,  36  minims  tincture  asafetida  and  5  minims 
tincture  opium.  Carminative,  Antidiarrheal.  Average  Dose : 
2  fluidrachms  (8  mils  [Cc.]). 

MIXTURE  OIL  TAR. 

Mislura  Olei  Picis,  N.  F.;  Tar  Mixture.  Containing  oil  tar 
(16.8  minims  per  fl.  oz.),  purified  extract  glycyrrhiza,  sugar, 
chloroform,  oil  peppermint,  alcohol  and  water.  Expectorant. 
Average  Dose:  2  fluidrachms  (8  mils  [Cc.]). 

MIXTURE,  OLEO-BALSAMIC. 

Mistura  Oleo-Balsamica,  N.  F.  1000  mils  (Cc.)  contain  4 
mils  each  oils  lavend«r,  cinnamon,  thyme,  lemon  and  nutmeg, 
4  eugenol,  16  balsam  Peru,  with  alcohol.  Carminative,  Analep- 
tic.  Dose:  10  to  30  minims  (0.6  to  2  mils  [Cc.]). 

MIXTURE    OPIUM,    ALKALINE.     See    Mixture    Opium    and    Sassa- 
fras. 

Mixture  Opium  and  Chloroform  Compound.      See  Tinc- 
ture  Opium   Compound. 

f  MIXTURE  OPIUM  AND  RHUBARB  COMPOUND. 

Mislura  Opii  el  Rhei  Composita,  N.  F.;  Sun  Cholera  Mix- 
ture. Mixture  of  1  volume  tincture  capsicum,  1  tincture  rhu- 
barb, 2  each  tincture  opium,  spirit  camphor,  spirit  peppermint 
and  alcohol.  Intestinal  Astringent,  Carminative.  Average 
Dose:  30  minims  (2  mils  [Cc.]). 

MIXTURE  OPIUM  AND  SASSAFRAS. 

Mistura  Opii  el  Sassafras,  N.  F.;  Godfrey's  Cordial;  Alkaline 
Mixture  of  Opium.  Each  fluidounce  contains  1 .6  grains  opium, 
4  grains  potassium  carbonate  and  0.5  minim  oil  sassafras.  Car- 
minative, Sedative;  in  colic,  diarrhea,  etc.  Average  Dose :  (in- 
fants'): 5  minims  (0.3  mil  [Cc.]). 


SQUIBB'S  MATERIA  MEDICA        163 

MIXTURE,  PARRISH'S.    See  Mixture  Camphor  Aromatic. 

Mixture   Pectoral    (Stokes'),   Squibb  pint 

Mislura  Pectoraiis  Slopes,  N.  F.;  Stokes'  Expectorant.  Each 
fluidounce  represents  8  grains  ammonium  carbonate,  16  grains 
each  senega  and  squill,  and  84  minims  camphorated  tincture 
opium,  with  syrup  tolu  and  water.  Average  Dose:  1  fluidrachm 
(4  mils  [Cc.]). 

Mixture  Rhubarb  Alkaline,  Squibb  pint 

Mistura  Rhei  Al^alina,  N.  F.;  Syrup  Rhubarb  and  Potassa 
Compound;  Neutralizing  Cordial.  Each  fluidounce  represents 
about  7J/2  grains  each  rhubarb  and  potassium  carbonate,  and 
3|4  grains  hydrastis,  with  tincture  cinnamon,  spirit  peppermint, 
syrup  and  alcohol.  Antacid,  Stomachic.  Average  Dose:  1 
fluidrachm  (4  mils  [Cc.]).  Incompatible  with  acids  or  alka- 
loidal  salts. 

MIXTURE  RHUBARB  AND  POTASSIUM  COMPOUND.    See   Mixture 
Rhubarb  Alkaline. 

Mixture   Rhubarb   and   Soda.     See    Mixture   Rhubarb  Com- 
pound. 

Mixture   Rhubarb  Compound,  Squibb  pint, 

Mistura  Rhei  Composite,  N.  F.;  Mixture  Rhubarb  and  Soda. 
Each  fluidounce  contains  about  16  grains  sodium  bicarbonate, 
7.2  minims  fluidextract  rhubarb,  1 .4  minims  fluidextract  ipecac, 
168  minims  glycerin,  16.8  minims  spirit  peppermint.  Incom- 
patible with  acids  and  with  solutions  of  alkaloidal  salts.  Stom- 
achic, Antacid.  Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 
(NoTE. — On  request  we  will  supply  specially,  in  lots  of  1  gal- 
lon or  more  Mixture  Rhubarb  Compound  made  in  accordance 
with  the  original  formula  of  Dr.  E.  R.  Squibb.  On  such 
orders  please  specify  "Original  Squibb  Formula.") 

MIXTURE    SASSAFRAS    AND    OPIUM.     See    Mixture    Opium    and 
Sassafras. 

MIXTURE  SODA  AND  SPEARMINT.    See  Solution  Soda  and  Mint. 
MIXTURE  TAR.     See  Mixture  Oil  Tar. 
Monobromethane.       See  Ethyl  Bromide. 
MoNOBROMlSOVALERYLUREA.     See  Bromural. 
Monochlorethane.        See  Ethyl  Chloride. 
Monsel's  Salt.         See  Iron  Subsulphate. 


The  prices  of  the  Squibb  Products  are  in  all  instances  as  low  as 
the  quality  and  quantity  of  ingredients  and  the  expense  of  man- 
ufacture allow.  They  include  containers,  packing  and  boxing.  When 
ordering  or  prescribing  medicinal  products,  specify  SQUIBB'S. 


164       SQUIBB'S  MATERIA  MEDICA 

Monsel's   Solution.         See  Solution  Iron  Subsulphate. 

f0  Morphine,  Squibb  Y&-OZ.  vial, 

Morphina.  CiyHigOgN.r-^O.  White,  odorless,  bitter  prisms, 
needles  or  powder.  1  Gm.  dissolves  in  3340  mils  (Cc.)  water, 
210  alcohol,  1220  chloroform,  6250  ether.  Analgesic,  Sedative, 
Hypnotic.  Average  Dose:  ]/&  grain  (0.008  Gm.).  Antidotes: 
potassium  permanganate;  apomorphine  hypodermically  as  emetic; 
atropine;  strychnine  or  caffeine;  strong  hot  coffee;  exercise. 

t  Morphine  Acetate,  Squibb  Y&-OZ.  vial, 

Morphine  Acetas,  U.  S.  P.  VHIth  Rev.  C17Hi9O3N.- 
C2H4Oo.3H2O.  White  or  yellowish-white,  bitter  powder; 
faint  acetous  odor.  Soluble  in  2.25  parts  water,  21.6  alcohol, 
480  chloroform,  5.2  glycerin.  Becomes  less  soluble  ontexposure. 
Incompatible  in  solution  with  alkalies,  tannin,  borax,  bromides, 
chlorates,  iodides,  spirit  nitrous  ether,  or  mercury  bichloride. 
Average  Dose:  ]/4  grain  (0.015  Gm.).  Keep  well  stoppered. 

f®  Morphine  Hydrochloride,  Squibb  |/g-oz.  vial, 

Morphines  Hydrochloridum.  Ci7Hi9O3N.HC1.3H2O.  White, 
silky,  odorless,  bitter  needles,  cubes  or  powder.  1  Gm.  dis- 
solves in  17.5  mils  (Cc.)  water,  52  alcohol,  8  glycerin;  insol- 
uble in  ether  or  chloroform. 

t©  Morphine  Sulphate,  Squibb 

Morphine  Sulphas.  (CiTHigOsN^.HaSC^.SHoO.  White, 
feathery,  silky,  odorless,  bitter  flakes  or  cubes.  1  Gm.  dis- 
solves in  15.5  mils  (Cc.)  water,  565  alcohol;  insoluble  in  ether 
or  chloroform. 

Mountain  Balm.     See  Eriodictyon. 

©  MUCILAGE  ACACIA. 

Mucilago  Acaciee.  35  percent,  acacia.  Demulcent,  but  used 
chiefly  pharmaceutically.  Incompatible  with  alcohol,  ether, 
ammonia  and  strongly  alcoholic  or  ethereal  fluidextracts  and  tinc- 
tures. Average  Dose:  4  fluidrachms  (16  mils  [Cc.)].  Readily 
becomes  sour  or  mouldy,  hence  should  be  made  frequently. 

MUCILAGE  CHONDRUS. 

Mucilago  Chondri,  N.  F.;  Mucilage  Irish  Moss.  3  Gm.  in 
100  mils  (Cc.).  Emulsifier,  Demulcent. 

MUCILAGE  SASSAFRAS  PITH. 

Mucilago  Sassafras  Medulla,  N.  F.  2  Gm.  in  100  mils  (Cc.). 
Emollient,  Demulcent,  Refrigerant.  Average  Dose:  4  fluid 
drachms  (16  mils). 


SQUIBB'S  MATERIA  MEDICA        165 

MUCILAGE  TRAGACANTH. 

Mucilago  Tragacanthce.  6  percent,  tragacanth,  18  glycerin. 
Excipient  for  troches,  lozenges,  etc. 

MULLEIN  FLOWERS. 

Verbasci  Flares,  N.  F.  Dried  corollas,  with  adhering  stamens, 
of  Verbascum  phlomoides  or  of  V '.  thapsiforme  (Fam.  Scro- 
phulariacete) .  Demulcent,  Vulnerary.  Average  Dose:  2 
drachms  (8  Gm.). 

MULLEIN  LEAVES. 

Verbasci  Folia,  N.  F.  Demulcent,  Anticatarrhal.  Average 
Dose:  1  drachm  (4  Gm.). 

MULLS. 

Mulls;  Salve  Mulls.  Ointments  of  high  fusing  points, 
spread  on  soft  muslin  or  "mull."  The  following  mulls  are  noted 
in  N.  F.:— 

Acid  Salicylic:  10%;  Creosote  Salicylated :  20%  creosote, 
10%  salicylic  acid;  Mercuric  Chloride:  0.2%;  Zinc: 
10%  zinc  oxide. 

MUSK. 

Moschus;  Deer  Musk;  Tonquin  Musk.  Dried  secretion  from 
preputial  follicles  of  Moschus  moschiferus  (Fam.  Moschidcs). 
Irregular,  blackish,  shiny  grains;  peculiar  penetrating,  per- 
sistent odor;  bitterish  taste.  Soluble  in  water  to  about  50  per- 
cent.; in  alcohol,  10  percent.  Antispasmodic,  Analeptic;  used 
largely  in  perfumery.  Average  Dose :  4  grains  (0.25  Gm.). 

MUSK-ROOT.     See  Sumbul. 

Mustard,  Powdered,  Squibb  tin,  lb. 

sprinkler-top  tins,  4-oz.,  per  doz. 

2-oz.,  per  doz. 

Sinapis  Alba;  White,  Yellow,  or  English  Mustard.  Ripe  seed 
of  Sinapis  alba,  carefully  reduced  to  a  coarse  powder.  Free 
from  adulteration  or  added  coloring-matter.  Emetic,  Counter- 
irritant;  Condiment.  Average  Dose:  150  grains  (10  Gm.),  in 
lukewarm  water.  In  making  mustard  plaster  cold  ivater,  that 
is  water  at  ordinary  room  temperature,  should  be  employed  to 
obtain  satisfactory  results.  Boiling  water  destroys  the  enzyme 
which  produces  the  useful  volatile  oil  of  mustard;  hence  a 
plaster  made  with  it  will  not  be  active.  For  making  table 
mustard,  take:  Squibb's  Powdered  Mustard,  3  teaspoonfuls; 
Table  Salt,  !/4  teaspoonful ;  Powdered  Sugar,  1  teaspoonful ; 
Cider  Vinegar,  8  teaspoonfuls.  Mix  the  first  three  ingredients 
well,  then  add  the  vinegar  with  constant  stirring. 


If  difficulty  is  experienced  in  procuring  any  Squibb  product, 
in  the  original  packages  here  listed,  please  notify  us;  we 
shall  see  that  your  wants  are  met  promptly  and  satisfactorily. 


166       SQUIBB'S  MATERIA  MEDICA 

Myristica.        See  Nutmeg. 

®  Myrrh,  Squibb  Ground  for  Percolation        tin,  lb. 

Myrrha;  Gum  Myrrh.  Gum-resin  from  Commiphora  Myrrha 
and  other  species  of  Commiphora  (Fam.  Burseraceas) .  Best 
quality,  insuring  perfect  satisfaction  in  its  use.  Roundish  or 
irregular,  brownish-yellow  to  reddish-brown  tears  or  masses; 
balsamic  odor;  aromatic,  bitter  and  acrid  taste.  Astringent, 
Protective;  Carminative.  Average  Dose:  8  grains  (0.5  Gm.). 
(See  Tincture.) 

Naphthol,    Beta-.        See  Betanaphthol. 

®  NEOARSPHENAMINE. 

Neosalvarsan ;  Arsphenolamine-S.  3  Gm.  equal  2  Gm. 
Arsphenamine  in  arsenic  content.  Orange-yellow  powder; 
peculiar  odor;  unstable  in  air.  Readily  soluble  in  water. 
Dose:  men,  12  grains  (0.8  Gm.)  ;  women,  9  grains  (0.6  Gm.)  ; 
children,  2J/2  to  5  grains  (0.15  to  0.3  Gm.) — intravenously  or 
by  intramuscular  injection. 

NEOSALVARSAN.     See  Neoarsphenamine. 

NickeUAmmonium  Sulphate  Reagent.    See  Reagents  (Part 
IV). 

Nickel  Nitrate  Reagent.  See  Reagents  (Part  IV). 
Nickel   Sulphate   Reagent.  See  Reagents  (Part  IV). 
NlOFORM.     See  Vioform. 
NITROGLYCERIN  SPIRIT.     See  Spirit  Glyceryl  Trinitrate. 

NOVARGAN. 

Silver  Proteinate.  10  percent,  silver.  Yellow  powder.  Solu- 
ble in  water.  Astringent,  Bactericide;  like  silver  nitrate.  Used 
in  10  to  20  percent,  solutions. 

NOVASPIRIN. 

Methylenecitrylsalicylic  Acid.  White,  odorless,  acidulous  pow- 
der. Soluble  freely  in  alcohol;  sparingly  in  chloroform,  ether; 
almost  insoluble  in  water.  Antirheumatic,  Antiseptic.  Dose : 
10  to  20  grains  (0.65  to  1.3  Gm.). 

NOVOCAIN.     See  Procaine. 

NuCLEIN. 

A  modified  nucleoprotein  obtained  by  peptic  digestion  or  treat- 
ment with  dilute  acids.  Grayish-white  powder.  Soluble  in  dilute 
alkalies,  slightly  in  water;  insoluble  in  alcohol.  Systemic 
Bactericide,  Leucocytotic,  Alterative.  Dose:  8  to  15  grains 
(0.5  to  1  Gm.),  3  times  daily. 


SQUIBB'S  MATERIA  MEDICA        167 

NUTGALL. 

Calla;  Galls.  Excrescence  on  Quercus  infecloria  and  allied 
species  (Fam.  Fasacece),  caused  by  punctures  and  deposited 
ova  of  Cpnips  tinctoria.  Nearly  odorless;  strongly  astringent 
taste.  External  and  Internal  Astringent.  Average  Dose:  8 
grains  (0.5  Gm.). 

Nutmeg,  Squibb 

*Whote  tin,  Ib.          ;  %  Ib.          ;  2-oz.,  per  doz. 

Powdered  tin,  Ib. 

sprinkler-top  tins,  4-oz.,  per  doz. 

2-oz.,  per  doz. 

1  -oz.,  per  doz. 

Myristica.  Choice  unsophisticated  grade.  Kernel  of  ripe  seed 
of  Myrlslica  fragrans  (Fam.  Afpn'sficaceoe).  Aromatic,  Car- 
minative; Condiment.  A  method  of  adulterating  nutmeg  consists 
in  extracting  the  oil  by  boring  a  hole  through  the  middle,  boiling 
with  water  and  then  closing  the  hole  so  carefully  that  the  nut- 
meg may  be  sold  without  the  fraud  being  detected.  Average 
Dose:  8  grains  (0.5  Gm.). 

NUTROSE. 

Casein-sodium.  Obtained  from  freshly  precipitated  casein  by 
action  of  sodium  hydroxide.  Coarse,  white,  odorless,  nearly 
-tasteless,  alkaline  powder.  Soluble  in  water.  Incompatible 
with  acids.  Nutritive.  Dose:  2  to  4  drachms  (8  to  16  Gm.). 

0  Nux  Vomica,  Squibb 

Ground  for  Percolation  tin,  Ib. 

Nux  Vomica;  Quaker  Buttons;  Poison  Nut.  Dried,  ripe  seeds 
of  Slrychnos  Nux-vomica  (Fam.  Loganiacea) .  Assays  not  less 
than  2.5  percent,  total  alkaloids.  Bitter  Stomachic,  Tonic. 
Average  Dose:  1  grain  (0.065  Gm.).  Antidotes:  emetics; 
chloral  hydrate  with  bromides  per  rectum;  chloroform  inhala- 
tion and  artificial  respiration  if  required.  (See  also  Extract; 
Fluidextract;  Tincture.) 

Occult  Blood  Test  Tablets.     See  under  Tablets  (Part  II). 

OIL  ALMOND  EXPRESSED. 

Oleum  AmygJalcs  Expressum;  "Oil  Sweet  Almond."  Fixed 
oil  from  kernels  of  various  varieties  of  Prunus  Amygdalus 
(Fam.  Rosaces).  Clear,  pale  straw-colored,  almost  odorless 
liquid;  bland  taste.  Miscible  with  ether,  chloroform;  slightly 
soluble  in  alcohol.  Sp.  gr.  0.910  to  0.915.  Emollient,  Demul- 
cent, Nutrient,  Laxative.  Ordinary  Dose :  4  fluidrachms  (16 
mils  [Cc.]). 


The  Squibb  products  are  recognized  everywhere  as  the  Quality 
Standard.  They  are  of  uniform  purity  and  strength,  hence 
therapeutically  dependable.  When  ordering  or  prescribing  med- 
icinal products,  you  will  do  well  always  to  specify  SQUIBB'S. 


168       SQUIBB'S  MATERIA  MEDICA 

OIL  ALLSPICE.    See  Oil  Pimenta. 

OIL  ANISE. 

Oleum  Anisi.  Volatile  oil  from  ripe  fruit  of  Pimpinella  Ani- 
sum  (Fam.  Umbelliferai)  or  of  Illicium  verum  (Star  Anise; 
Fam.  Magnoliacece).  Pale-yellow;  characteristic  odor;  sweet- 
ish, aromatic  taste.  Sp.  gr.  0.978  to  0.988.  Solidifies  at  about 
15°  C.  (59°  F.).  Soluble  in  about  equal  volume  strong  al- 
cohol. Aromatic  Carminative;  Flavor.  Average  Dose: 
3  minims  (0.2  mil  [Cc.]). 

OIL  BAY.     See  Oil  Myrcia. 
OIL  BENNE.    See  Oil  Sesame. 

Oift  BERGAMOT. 

Oleum  Bergamottts,  N.  F.  Volatile  oil  expressed  from  rind 
of  fresh  fruit  of  Citrus  Auranllum  Bergamia  (Fam.  Ruiacea), 
containing  not  less  than  36  percent,  ester  calculated  as  linalyi 
acetate.  Green  or  greenish-yellow  oil;  fragrant  odor;  aro- 
matic, bitter  taste;  sp.  gr.  0.875  to  0.880.  Soluble  in  0.5  vol- 
ume alcohol,  2  volumes  80-percent,  alcohol.  Used  principally 
in  perfumery  and  toilet  preparations. 

<B  Oil  Betula,  Squibb 

bottle,  Ib.          ;  %  Ib.          ;  oz. 

Oil  Sweet  Birch.  Volatile  oil  distilled  from  bark  of  Betula 
lenla  (Fam.  Betulacece).  Practically  identical  with  oil  gaul- 
theria  and  methyl  salicylate;  colorless  or  nearly  so;  strong, 
aromatic  odor;  sweetish,  warm,  aromatic  taste.  Sp.  gr.  1.172 
to  1.182.  .Antirheumatic,  Antipyretic;  Flavor.  Dose:  10  to 
20  minims  (0.6  to  1.2  mils  [Cc.]). 

Oil   Birch.     See  Oil  Betula. 

OIL  BIRCH  TAR,  RECTIFIED. 

Oleum  Betulas  Empyreumatlcum  Rectificatum,  N.  F.;  Oleum 
Rusci  Rectificatum.  Pyroligneous  oil  obtained  by  dry  distilla- 
tion of  bark  and  wood  of  Betula  alba  (Fam.  Betulaceaz), 
rectified  by  steam  distillation.  Dark-brown  oil;  penetrating, 
empyreumatic  odor  like  Russian  leather;  sp.  gr.  0.886  to  0.950. 
Soluble  in  ether,  chloroform;  3  volumes  alcohol.  Antiparasitic 
Dermic. 

OIL  BITTER  ALMOND. 

Oleum  Amygdala  Amarce.  Volatile  oil  obtained  by  macera- 
tion and  distillation  of  ripe  kernels  of  Prunus  Amygdalus 
amara  (Fam.  Rosacece),  yielding  85  percent,  benzaldehyde 
and  2  to  4  percent,  hydrocyanic  acid.  Clear,  colorless  or  yel- 
low oil;  bitter-almond  odor  and  taste;  sp.  gr.  1.038  to  1.060. 
Slightly  soluble  in  water;  miscible  with  alcohol  or  ether  in  all 
proportions.  Cough  Sedative,  Antipruritic ;  Flavor.  Average 
Dose:  |/2  minim  (0.03  mil  [Cc.]).  Antidotes:  hydrogen  per- 
oxide by  mouth  and  subcutaneously;  emetics;  ammonia  or  atro- 
pine  as  stimulant. 


SQUIBB'S  MATERIA  MEDICA        169 

Oil  Bitter  Almond,  Artificial.       See  Benzaldehyde. 

OIL  BITTER  ORANGE.  4& 

Oleum  Auranlii  Amari,  N.  F.  Volatile  oil  expressed  from 
fresh  peel  of  bitter  orange.  Citrus  Aurantium  amara  (Fam. 
Rutacece).  Pale-yellow  oil;  orange  odor;  aromatic,  slightly 
bitter  taste;  sp.  gr.  0.842  to  0.848.  Soluble  in  4  volumes  alco- 
hol. Aromatic  Flavor.  Average  Dose:  3  minims  (0.2 
mil  [Cc.]).  Oil  bitter  orange  having  a  terebinthinate  odor 
should  not  be  dispensed. 

OIL  CADE. 

Oleum  Cadinum;  Oil  Juniper  Tar.  Empyreumatic  oil  ob- 
tained by  dry  distillation  of  wood  of  Juniperus  OxpceJrus 
(Fam.  Pinaced).  Dark-brown,  thick  liquid;  tarry  odor;  faint- 
ly aromatic,  bitter,  burning  taste.  Soluble  in  3  volumes  ether; 
in  chloroform,  oil  turpentine,  amyl  alcohol ;  almost  insoluble 
in  water;  partly  soluble  in  alcohol.  Epidermal  Stimulant,  Anti- 
parasitic  Dermic. 

OIL  CAJUPUT. 

Oleum  Cajupuii.  Volatile  oil  from  fresh  leaves  and  twigs  of 
several  varieties  of  Melaleuca  Leucadendron  (Fam.  Myr- 
taceai).  Colorless  or  yellowish;  agreeable,  camphoraceous 
odor;  aromatic,  slighly  bitter  taste.  Sp.  gr.  0.912  to  0.925. 
Miscible  with  alcohol.  Counter-irritant,  externally;  Stimulant, 
Alterative,  internally.  Average  Dose:  8  minims  (0.5  mil 
[Cc.]). 

Oil,   Camphorated.  See  Liniment  Camphor. 

OIL  CARAWAY. 

Oleum  Can.  Volatile  oil  from  fruit  of  Carum  Carvi  (Fam. 
UmbellifertE*).  Colorless  or  pale-yellow;  characteristic  aro- 
matic odor  and  taste.  Sp.  gr.  0.900  to  0.910.  Yields  about 
50  volume  percent,  carvone.  Soluble  in  equal  volume  alcohol, 
8  volumes  80  percent,  alcohol.  Carminative,  Aromatic,  Corri- 
gent.  Average  Dose:  3  minims  (0.2  mil  [Cc.]) 

OIL  CARBOLIZED.     See  Oil    Phenolated. 

OIL  CARDAMOM. 

Oleum  Cardamom!,  N.  F.  Volatile  oil  distilled  from  seeds  of 
Eletlaria  Cardamomum  (Fam.  Zingiberacece) .  Colorless,  pale- 
yellow  oil;  aromatic,  somewhat  camphoraceous  odor;  persistent, 
pungent,  strongly  aromatic  taste;  sp.  gr.  0.924  to  0.947.  Solu- 
ble freely  in  alcohol;  in  4  volumes  70-percent,  alcohol.  Aro- 
matic, Carminative;  Flavoring.  Dose:  I  to  2  minims  (0.06  to 
0.12  mil  [Cc.]) 


Since  we  make  only  one  quality  of  each  product,  that  best 
suited  to  the  purposes  intended,  the  specification  "Squibb's" 
is  not  open  to  various  interpretations,  but  has  a  plain,  positive 
meaning.  When  ordering  or  prescribing,  specify  SQUIBB'S. 


170        SQUIBB'S  MATERIA  MEDICA 

OIL,  CARRON.    See  Liniment  Lime. 

©  OIL  CASSIA. 

Oleum  Cassias;  Oil  Cinnamon.  Volatile  oil  from  Cfnna- 
momum  Cassia  (Fam.  Lauraceee).  Yields  about  80  volume 
percent,  cinnamic  aldehyde.  Yellowish  or  brownish,  darkening 
and  thickening  with  age;  characteristic  odor  and  taste  of  cinna- 
mon. Sp.  gr.  1 .045  to  1 .063.  Carminative,  Aromatic  Flavor. 
Average  Dose:  3  minims  (0.2  mil  [Cc.]). 

©  Oil   Castor,  Squibb      bottle,  Ib.         ;  '/2  lb-         ;  %  lb- 

Oleum  Ricini.  Fixed  oil  expressed  from  seeds  of  Ricinus  com- 
munis  (Castor  Bean;  Fam.  Euphorbiaceas) .  An  exceptionally 
pure  medicinal  quality.  Of  much  less  disagreeable  odor  and 
taste  than  attend  the  regular  market  article,  and  perfectly  re- 
liable physiologically.  Pale-yellowish  or  almost  colorless,  trans- 
parent, viscid  liquid,  of  faint  odor,  and  bland,  later  slightly 
acrid  and  offensive  taste.  Sp.  gr.  0.945  to  0.965.  Soluble  in 
equal  volume  alcohol.  Efficient  and  prompt  Cathartic;  useful 
also  as  initial  purge  in  acute  diarrheas.  Average  Dose : 

4  fluid  rachms    (15   mils    [Cc.]),  between  meals.     Acts   in  4  to 

5  hours. 

Oil    Castor    Aromatic,    Squibb         bottle,  Ib.         ;  %  Ib. 

Oleum  Ricini  Aromalicum,  N.  F.  Preceding  oil  flavored  with 
oil  cinnamon,  oil  clove,  vanillin  and  coumarin,  and  sweetened 
with  benzosulphmide.  Especially  designed  for  children  and 
for  adults  having  a  repugnance  for  plain  castor  oil. 

©  OIL  CHENOPODIUM. 

Oleum  ChenopoJii ;  Oil  American  Wormseed.  Volatile  oil 
from  ChenopoJium  ambrosioiJes  anlhelminlicum  (Fam.  Cheno- 
podiacece).  Colorless  or  pale-yellow;  disagreeable  camphora- 
ceous  odor;  pungent,  bitter  taste.  Sp.  gr.  0.955  to  0.980.  Solu- 
ble in  8  volumes  70-percent,  alcohol.  Anthelmmtic,  especially 
for  round  worms  and  hookworms.  Average  Dose :  3  minims 
(0.2  mil  [Cc.]). 

OIL  CINNAMON.    See  Oil  Cassia. 

©  OIL  CLOVE. 

Oleum  Caryophylli.  Volatile  oil  from  flower-buds  of  Eugenia 
.  aromalica,  Jambosa  Carp  op /ip //us  (Fam.  Myrtacece).  Colorless 
or  pale-yellow,  becoming  darker  and  thicker  with  age;  strong 
aromatic  odor;  pungent  taste;  sp.  gr.  1.038  to  1.060.  Yields 
not  less  than  92  volume  percent,  of  eugenol.  Soluble  in  2  vol- 
umes 70  percent,  alcohol.  Rubefacient,  Counter-irritant,  ex- 
ternally; Carminative,  internally.  Average  Dose:  3  minims 
(0.2  mil  [Ce.]). 


SQUIBB'S  MATERIA  MEDICA        171 

©  Oil  Cod  Liver,  Squibb 

bottle,  pint          ;  ^2  pint          ;  '/4  pint 

Oleum  Morrhuai ;  Cod  Oil.  Fixed  oil  obtained  from  fresh 
livers  of  Gadus  morrhua  and  other  species  of  Gadus  (Fam. 
Gadida).  A  Norwegian  oil,  of  highest  purity  obtainable; 
light-straw  color,  fresh  and  bland  in  taste,  and  extracted  from 
the  livers  before  decomposition  has  set  in.  It  is  consequently 
much  superior  medicinally  to  the  dark-colored,  rancid  oils  of 
common  knowledge.  It  is  imported  from  Norway  in  the  colder 
months  of  the  year  and  at  once  bottled  in  order  to  avoid  even 
the  start  of  rancidity.  Therapeutically  the  Norway  oil  has  been 
proved  preferable  to  oils  obtained  from  any  other  part  of  the 
world.  Particular  attention  is  called  to  the  agreeable  or  rather 
not  disagreeable  odor  and  taste  of  this  oil.  Sp.  gr.  0.918  to 
0.922.  Soluble  readily  in  ether  or  chloroform,  in  2  parts  acetic 
ether,  very  slightly  in  alcohol.  Alterative  Tonic,  Nutrient. 
Occasionally  employed  topically  (in  certain  chronic  skin  dis- 
eases). Average  Dose:  2]/2  fluidrachms  (10  mils  [Cc.]),  two 
hours  alter  meals,  or  at  bedtime. 

OIL  CORIANDER. 

Oleum  Coiiandri.  Volatile  oil  from  ripe  fruit  of  Coriandrum 
sativum  (Fam.  Umbelliferce).  Colorless  or  pale-yellow;  spicy 
odor  and  taste;  sp.  gr.  0.863  to  0.875.  Soluble  in  3  volumes 
70-percent,  alcohol.  Aromatic,  Carminative.  Average  Dose: 
3  minims  (0.2  mil  [Cc.]). 

Oil  Cotton=Seed,  Squibb  bottle,  Ib. 

Oleum  Gossypii  Seminis.  Fixed  oil  expressed  from  seeds  of 
cultivated  varieties  of  Cossppiu/n  herbaceum  and  other  species 
of  Gossypium  (Fam.  Malvacea).  An  especially  purified  product, 
particularly  adapted  to  pharmaceutical  and  medicinal  uses. 
Pale-yellow,  odorless  liquid,  of  bland,  nut-like  taste.  Sp.  gr. 
0.915  to  0.921.  Readily  soluble  in  ether  or  chloroform,  very 
sparingly  in  alcohol.  Demulcent,  Emollient,  Nutrient;  fre- 
quently used  in  place  of  olive  oil  in  preparations  for  external 
use.  Dose:  2  to  4  fluidrachms  (8  to  16  mils  [Cc.]). 

0  OIL  CROTON. 

Oleum  Tiglii.  Fixed  oil  expressed  from  seeds  of  Crolon 
Tiglium  (Fam.  Euf>horl>iace<s) .  Pale-yellow  or  brownish- 
yellow;  slightly  viscid  and  fluorescent;  slight,  fatty  odor;  mild, 
acrid,  burning  taste.  Produces  pustular  eruption  when  applied 
to  skin.  Sp.  gr.  0.935  to  0.950.  Freely  soluble  in  ether, 
chloroform,  oils;  slightly  soluble  in  alcohol.  Drastic  Cathartic, 
Rubefacient,  Vesicant.  Average  Dose:  1  minim  (0.06  mil 
[Cc.]),  on  sugar  or  in  pills  with  bread  or  other  absorbent. 
Antidotes :  bland  oils,  mucilage,  atropme,  cocaine. 


The  founder  of  the  House  of  Squibb,  Dr.  Edward  R.  Squibb, 
not  only  had  high  ideals,  but  lived  and  labored  for  them;  and, 
in  the  words  of  William  Miller  Bartlett,  "the  House  of  Squibb 
stands  today  as  a  living  monument  to  the  honor,  integrity,  zeal 
and  devotion  of  its  founder." 


172        SQUIBB'S  MATERIA  MEDICA 

OIL  CUBEB. 

Oleum  CubebcB.  Volatile  oil  from  unripe  fruit  of  Piper 
Cubeba  (Fam.  Piperacece),  Colorless,  pale-green  or  yellow- 
ish-green; characteristic  odor;  warm,  camphoraceous  taste;  sp. 
gr.  0.905  to  0.925.  Soluble  in  about  equal  volume  alcohol. 
Stimulating  Antiseptic,  Expectorant,  Urinary  Anticatarrhal. 
Average  Dose:  8  minims  (0.5  mil  [Cc.]). 

OIL  CYPRESS. 

Volatile  oil  from  Cupressus  sempervirens.  Yellowish  liquid; 
pleasant  odor;  sp.  gr.  0.88  to  0.89.  Soluble  in  alcohol.  Anti- 
spasmodic;  chiefly  in  whooping-cough  by  inhalation,  a  table- 
spoonful  of  1  :5  alcoholic  solution  being  poured  three  or  four 
times  daily  over  pillow,  gown  and  underwear. 

Oil  Ethereal,  Squibb  g.  s.  bottle,  oz. 

Oleum  /Elhereum,  N.  F.  Dropped  from  U.  S.  P.  Not  in- 
frequently the  composite,  indeterminate  residue  from  the  ether 
still,  and  a  nondescript  distillate  from  grapes,  are  marketed  as 
"oil  of  wine."  The  Squibb  product  is  prepared  from  pure 
materials  in  absolute  compliance  with  N.  F.  process  and  for- 
mula, and  none  of  it  that  is  not  of  uniform  best  quality  is  al- 
lowed to  leave  the  laboratory.  Transparent,  nearly  colorless, 
volatile  liquid;  aromatic,  ethereal  odor;  pungent,  refreshing,  bit- 
terish taste;  sp.  gr.  about  0.905.  An  ingredient  of  Spirit  Ether 
Compound  (Hoffmann's  Anodyne) ;  not  used  by  itself  medi- 
cinally. 

©  OIL  EUCALYPTUS. 

Oleum  Eucalypti.  Volatile  oil  from  fresh  leaves  of  Euca- 
lyptus globulus  or  other  species  of  Eucalyp lus  (Fam.  Mpr/acece), 
yielding  not  less  than  70  vol.  percent,  eucalyptol.  Colorless 
or  pale-yellow;  spicy  taste;  sp.  gr.  0.905  to  0.925.  Soluble 
in  4  volumes  70-percent,  alcohol.  Antiseptic,  Deodorant; 
largely  used  by  inhalation  as  vapor  or  oil  sprays  in  subacute 
and  chronic  inflammations  of  respiratory  tract.  Average  Dose : 
8  minims  (0.5  mil  [Cc.]). 

OIL  FENNEL. 

Oleum  Fccn/cu/t.  Volatile  oil  from  ripe  fruit  of  cultivated 
varieties  of  Faenlculum  vulgare  (Fam.  Umbelllferce).  Color- 
less or  pale-yellow;  characteristic  odor;  mild,  sweetish,  spicy 
taste;  sp.  gr.  0.953  to  0.973.  Soluble  in  8  volumes  80-percent, 
alcohol.  Aromatic  Carminative,  Corrigent  of  griping  action  of 
cathartics.  Average  Dose:  3  minims  (0.2  mil  [Cc.]). 

OIL  GAULTHERIA.     See  Oil  Betula  and  Methyl  Salicylate. 

OIL  HYOSCYAMUS  COMPOUND. 

Oleum  Hyoscyami  Compositum,  N.  F.  1000  mils  (Cc.)  con- 
tain 2  mils  each  oils  lavender,  peppermint,  rosemary  and  thyme, 
infused  oil  hyoscyamus  q.  s.  Anodyne  embrocation. 


SQUIBB'S  MATERIA  MEDICA        175 

OIL  JUNIPER. 

Oleum  /uniperi.  Volatile  oil  from  ripe  fruit  of  Juniperus  corn- 
mums  (Fam.  Pinaceat).  Colorless  or  faintly  green  or  yellow; 
characteristic  odor;  warm,  aromatic,  slightly  terebinthinate,  bit- 
terish taste;  sp.  gr.  0.854  to  0.879.  Soluble  in  4  volumes 
alcohol  (almost  clearly).  Irritant  Diuretic,  Carminative. 
Average  Dose:  3  minims  (0.2  mil  [Cc.]). 

OIL  JUNIPER  TAR.     See  Oil  Cade. 

OIL  LAVENDER. 

Oleum  LavanJulce.  Volatile  oil  from  fresh  flowering  tops  of 
Lavandula  vera  (L.  officinalis,  L,  spica;  Fam.  Labiaiai). 
Colorless  or  yellow;  fragrant  odor;  pungent,  bitterish  taste; 
sp.  gr.  0.875  to  0.888.  Soluble  in  3  volumes  70  percent,  alco- 
hol. Aromatic,  Stimulant,  Tonic;  Flavor,  Perfume.  Average 
Dose:  3  minims  (0.2  mil  [Cc.]). 

OIL  LEMON. 

Oleum  Limonis.  Volatile  oil  obtained  by  expression  from  fresh 
peel  of  ripe  fruit  of  Citrus  medico  Limonum  (Fam.  Rulaceas). 
yielding  not  less  than  4  percent,  citral.  Pale-yellow  or  greenish- 
yellow;  fragrant  odor;  aromatic,  slightly  bitterish  taste;  sp. 
gr.  0.851  to  0.855.  Stimulant,  but  used  mainly  as  flavoring, 
and  in  perfumery.  Average  Dose:  3  minims  (0.2  mil  [Cc.]). 
An  oil  having  a  terebinthinate  odor  should  not  be  dispensed. 

0  OIL  LINSEED. 

Oleum  Lini;  Raw  Linseed  Oil.  Fixed  oil  expressed  from 
linseed.  Yellowish;  slight  odor;  bland  taste;  thickens,  dark- 
ens and  acquires  strong  odor  and  taste  on  exposure;  sp.  gr. 
0.925  to  0.935.  Miscible  with  ether,  chloroform,  oil  turpen- 
tine; slightly  soluble  in  alcohol.  Protective  Emollient,  Laxa- 
tive. Average  Dose:  1  fluidounce  (30  mils  [Cc.]).  Boiled 
linseed  oil  must  not  be  dispensed  for  medicinal  use. 

Oil   Mineral.     See  Liquid  Petrolatum. 

0  OIL  MUSTARD  VOLATILE. 

Oleum  Sinapis  Volatile.  From  black  mustard,  or  synthetically. 
Yields  not  less  than  92  percent,  allyl  isothiocyanate.  Colorless 
or  pale-yellow;  very  pungent,  irritating  odor;  acrid  tasle; 
sp.  gr.  1.013  to  1.020.  Miscible  with  alcohol  or  ether.  Vesi- 
cant, Counter-irritant;  Stimulant.  Average  Dose:  J/g  minim 
(0.008  mil  [Cc.]),  well  diluted.  Antidotes:  demulcents;  mor- 
phine for  pain. 


The  Squibb  Ideals  have  taken  concrete  form  in  the  Squibb 
Products;  these  are  universally  recognized  as  standards  of 
uniform  Purity  and  Efficacy,  that  is,  general  Excellence  and 
Reliability.  Specify  SQUIBB'S  when  prescribing  or  ordering. 


174        SQUIBB'S  MATERIA  MEDICA 

OIL  MYRCIA. 

Oleum  Mprciff,  N.  F.;  Oil  Bay.  Volatile  oil  distilled  from 
leaves  of  Pimenla  acris  (Fam.  Myrtacece).  Yellow  or  brownish 
yellow  liquid;  pleasant,  aromatic  odor;  pungent,  spicy  taste. 
Sp.  gr.  0.962  to  0.990.  Almost  clearly  soluble  in  equal  volume 
alcohol.  Used  technically. 

OIL  MYRISTICA. 

Oleum  Myristica;  Oil  Nutmeg.  Volatile  oil  distilled  from 
kernel  of  ripe  seed  of  Myrislica  fragrans  (Fam.  Mpn'sh'cacece). 
Colorless  or  pale-yellow;  characteristic  odor;  warm,  spicy 
taste;  sp.  gr.  0.859  to  0.924.  Soluble  in  equal  volume  alcohol, 
3  volumes  90  percent,  alcohol.  Aromatic  Carminative;  flavor- 
ing. Average  Dose:  3  minims  (0.2  mil  [Cc.]). 

OIL  NEROI.I.     See  Oil  Orange  Flowers. 
OIL  NUTMEG.     See  Oil  Myristica. 

Oil  Olive,  Squibb 

special  bottle,  pint,  ;  '/2  pint,  ;  '/4  pint, 
Oleum  O/i'v<£.  Fixed  oil  expressed  from  fruit  of  Olea  europcea 
(Fam.  Oleacea).  The  best  quality  of  olive  oil  is  obtained  from 
olives  picked  before  maturity  and  immediately  pressed.  It  is 
then  called  "virgin  oil"  and  has  a  greenish  tinge.  The  residue 
of  crushed  olives  left  after  extraction  of  the  virgin  oil  is  thrown 
into  boiling  water,  which  drives  out  the  remaining  oil,  and  this, 
together  with  the  oil  extracted  from  wholly  ripe  olives,  consti- 
tutes .  the  common  oil  for  culinary  purposes  and  for  making 
soaps.  The  Squibb  oil  is  virgin  oil  of  especially  fine  flavor,  im- 
ported from  known  sources  and  absolutely  free  from  adultera- 
tion. Pale-yellow  or  light  greenish-yellow;  slight  odor;  nutty, 
oleaginous  taste,  with  faintly  acrid  after-taste.  Sp.  gr.  0.910 
to  0.915.  Soluble  readily  in  chloroform  or  ether,  very  sparingly 
in  alcohol.  Emollient,  Laxative,  Nutrient;  latterly  also  recom- 
mended for  restoring  the  opsonic  index  after  narcoses  and  in 
other  depressed  conditions  of  the  system.  Average  Dose:  1 
fluidounce  (30  mils  [Cc.]),  between  meals;  in  hepatic  colic, 
3  to  6  jluidounces  (90  to  180  mils) 

OIL  ORANGE. 

Oleum  Auranlii.  Volatile  oil  expressed  from  fresh  peel  of 
sweet  orange.  Yellow;  characteristic  aromatic  odor;  orange 
taste;  sp.  gr.  0.842  to  0.846.  Soluble  in  about  4  volumes 
alcohol.  Carminative;  aromatic  flavoring.  Average  Dose:  3 
minims  (0.2  mil  [Cc.]).  An  oil  having  a  terebinthinate  odor 
should  not  be  dispensed. 

OIL  ORANGE  FLOWERS. 

Oleum  Aurantii  Florum,  N.  F.;  Oil  Neroli.  Volatile  oil  dis- 
tilled from  fresh  flowers  of  bitter  orange,  Citrus  Aurantium 
amara  (Fam.  Rutacece).  Pale-yellow  oil;  fragrant  odor  like 
orange  blossoms;  aromatic,  sweet  then  bitter  taste;  sp.  gr. 
0.868  to  0.880.  Soluble  in  equal  volume  alcohol,  2  volumes 
80-percent,  alcohol.  Flavoring  agent. 


SQUIBB'S  MATERIA  MEDICA        175 

©  Oil  Peppermint,  Squibb  bottle,  lb.  ;  '/4  lb.  ;oz. 
Oleum  Menlha  Piperilct.  Volatile  oil  distilled  from  flowering 
plant  of  Mentha  piperila  (Fam.  Labials),  rectified  by  steam 
distillation.  Colorless  liquid;  strong  peppermint  odor;  marked 
aromatic,  pungent  taste,  followed  by  sensation  of  cold  when  air 
is  drawn  through  the  mouth;  sp.  gr.  0.896  to  0.908.  Soluble  in 

4  volumes  70-percent,  alcohol.     Aromatic  Carminative;    flavor- 
ing.    Average  Dose:  3  minims  (0.2  mil    [Cc.]),  well  diluted. 
(See  also  Spirit.) 

OIL,  PHENOLATED. 

Oleum   Phenolatum,   N.   F.;    Carbolized   Oil.      Olive  oil  with 

5  percent,    phenol    (Carbolic    Acid).      Mild    Local    Stimulant, 
Antipruritic. 

OIL  PHOSPHORATED. 

Oleum  Phosphoralum,  N.  F.  I  percent,  phosphorus  in  ex- 
pressed oil  almond  with  little  ether.  Reconstructive,  Anticachec- 
tic;  chiefly  in  rickets.  Average  Dose:  1  minim  (0.06  mil  [Cc.]). 

OlL    PlMENTA. 

Oleum  PimentcE ;  Oil  Allspice.  Volatile  oil  distilled  from 
fruit  of  Pimenla  officinalis  (Fam.  Myrlacece)  yielding  not  less 
than  65  vol.  percent,  eugenol.  Colorless,  yellow  or  reddish, 
becoming  darker  with  age;  allspice  odor  and  taste;  sp.  gr. 
1.018  to  1.048.  Soluble  in  equal  volume  90  percent,  alcohol, 
2  volumes  70-percent,  alcohol.'' Carminative;  flavoring  agent. 
Average  Dose:  3  minims  (0.2  mil  [Cc.]). 

OIL  PINE  NEEDLES. 

Oleum  Pini  Pumilionis ;  Dwarf-Pine  Oil.  Volatile  oil  from 
fresh  leaves  of  Pinus  Pumilio  (Pi'nus  moniana;  Fam.  Pinacece). 
Colorless  or  yellowish;  pleasant  odor;  bitter,  pungent  taste;  sp. 
gr.  0.853  to  0.869.  Soluble  in  about  5  volumes  alcohol.  Anti- 
septic, Anticatarrhal,  by  inhalation  or  internally,  in  tuber- 
culosis, chronic  bronchitis,  etc.  Dose :  1  to  5  minims  (0.06 
to  0.3  mil  [Cc.]). 

OIL  ROSEMARY. 

Oleum  Rosmarini.  Volatile  oil  distilled  from  fresh  flowering 
tops  of  Rosmarinus  officinalis  (Fam.  Labials),  yielding  not 
less  than  10  percent,  borneol.  Colorless  or  pale-yellow;  char- 
acteristic pungent  odor;  warm,  camphoraceous  taste;  sp.  .gr. 
0.894  to  0.912.  Soluble  in  10  volumes  80-percent,  alcohol; 
in  ether.  Carminative;  aromatic  flavoring.  Average  Dose:  3 
minims  (0.2  mil  [Cc.]). 

©  OIL  SANDALWOOD. 

Oleum  Sanlali;  Oil  Yellow  Sandalwood.  Volatile  oil  dis- 
tilled from  wood  of  Sanlalum  album  (Fam.  Santalaced), 
yielding  not  less  than  90-percent,  santalol.  Pale-yellow,  thick 
liquid;  aromatic  odor;  pungent,  spicy  taste;  sp.  gr. 0.965  to  0.980. 
Soluble  in  5  volumes  70-percent,  alcohol.  Urinary  Disinfectant 
and  Anticatarrhal.  Average  Dose:  8  minims  (0.5  mil  [Cc.]). 

The  Squibb  Label  on  a  package  is  a  positive  guaranty  for  the 
uniform  Purity  and  Reliability  of  the  product.  We  make  only 
ONE  quality:  the  SQUIBB  quality;  and  our  prices  are  as  low 
as  they  can  be  made  for  that  quality.  Specify  SQUIBB'S. 


176       SQUIBB'S  MATERIA  MEDICA 

OIL  SASSAFRAS. 

Oleum  Sassafras.  Volatile  oil  distilled  from  Sassafras  von'i- 
folium  (Fam.  Lauracea) .  Yellow  or  reddish-yellow;  sassa- 
fras odor;  warm  aromatic  taste;  tp.  gr.  1.065  to  1.077.  Soluble 
in  2  volumes  90-percent,  alcohol.  Aromatic  Carminative; 
Rubefacient;  flavoring.  Average  Dose:  3  minims  (0.2  mil 
[Cc.]). 

OIL  SESAME. 

Oleum  Sesaml;  Benne  Oil.  Fixed  oil  from  seeds  of  cultivated 
varieties  of  Sesamum  indicum  (Fam.  Pedaliaceai).  Pale-yel- 
low; almost  odorless;  bland  taste;  sp.  gr.  0.916  to  0.921.  Mis- 
cible  with  ether,  cholorform;  slightly  soluble  in  alcohol.  Nutri- 
ent, Emollient;  substitute  for  olive  oil. 

OIL  SPEARMINT. 

Oleum  Menlha  Viridis.  Volatile  oil  distilled  from  flowering 
plant  of  Mentha  spicala  (M.  ViriJrs;  Fam.  Labiates).  Color- 
less, yellow  or  greenish-yellow;  strong,  spearmint  odor;  hot, 
aromatic  taste;  sp.  gr.  0.917  to  0.934.  Aromatic  Carminative; 
flavoring.  Average  Dose:  3  minims  (0.2  mil  [Cc.]). 

OIL  TAR  RECTIFIED. 

Oleum  Picis  Liquids  Reclificatum.  Volatile  oil  distilled  from 
tar.  Thick;  dark  reddish-brown;  strong,  empyreumatic  odor 
and  taste;  sp.  gr.  0.960  to  0.990.  Soluble  in  alcohol,  ether. 
Antiparasitic  Dermic,  Expectorant.  Average  Dose;  3  minims 
(0.2  mil  [Cc.]). 

©  Oil   Theobroma,   Squibb  tin,  Ib. 

Oleum  Theobromalis ;  Cacao  Butter.  Fixed  oil  expressed  from 
roasted  seeds  of  Theobroma  Cacao.  Yellowish-white  solid; 
faint,  agreeable  odor;  bland,  chocolate-like  taste;  melts  at 
30°  to  35°  C.  Soluble  readily  in  ether,  chloroform,  oils. 
Used  pharmaceutically  and  technically;  also  as  Emollient  and 
Lubricant. 

OIL  THYME. 

Oleum  Thymi,  Volatile  oil  distilled  from  flowering  plant  of 
Thomas  vulgaris  (Fam.  Labialae),  containing  not  less  than 
20  vol.  percent,  phenols.  Colorless  or  reddish;  strong  thyme 
odor;  aromatic,  pungent  afterwards  cooling  taste;  sp.  gr.  0.894 
to  0.930.  Soluble  in  2  volumes  80-percent,  alcohol;  in  ether, 
chloroform.  Rubefacient,  Counter-irritant;  Carminative. 
Average  Dose:  3  minims  (0.2  mil  [Cc.]). 

OIL  TURPENTINE. 

Oleum  Terebinlhin<e ;  "Spirits  of  Turpentine."  Volatile  oil 
distilled  with  water  from  concrete  oleoresin  obtained  from 
Pinus  paluslris  or  other  species  of  Pinus  (Fam.  Pinaceai). 
Colorless;  inflammable;  characteristic  odor  and  taste;  sp.  gr. 
0.860  to  0.870.  Soluble  in  5  volumes  alcohol.  Rubefacient, 
Counter-irritant.  (See  also  Liniment,  and  following  oil.) 


SQUIBB'S  MATERIA  MEDICA        177 

©Oil  Turpentine  Rectified,  Squibb  bottle, lb. 

Oleum  Terebinlhina  Recllficalum.  For  medicinal  use.  Care- 
fully selected,  purified  by  thoroughly  washing  with  solution  of 
caustic  soda  and  rectifying  by  distillation,  only  three-fourths  of 
the  oil  being  recovered.  Only  this  rectified  product  should  be 
dispensed  when  oil  turpentine  is  required  for  internal  use.  Sp. 
gr.  0.856  to  0.865.  Anthelmintic,  Diuretic,  Antiseptic,  Car- 
minative; in  tympanitis,  tapeworm,  retention  of  urine,  phosphorus 
poisoning,  etc.  Average  Dose :  5  minims  (0.3  mil  [Cc.] ) ;  in 
tapeworm,  1  to  2  fluidrachms  (4  to  8  mils). 

Oil  Wine.        See  under  Oil  Ethereal. 

Oil  Wintergreen.        See  Methyl  Salicylate  and  Oil  Betula. 
Oil  Wintergreen,  Synthetic.       See  Methyl  Salicylate. 
OIL  WORMSEED,  AMERICAN.    See  Oil  Chenopodium. 

OILS,  INFUSED. 

Olea  Infusa,  N.  F.,  are  directed  to  be  made  by  macerating 
10  Gm.  dried  drug  with  10  mils  (Cc.)  alcohol  and  0.2  mil 
ammonia  water  for  6  hours,  then  adding  100  Gm.  sesame  oil 
and  warming  the  mixture  on  water-bath  at  60°  to  70°  C.  until 
the  alcohol  and  ammonia  are  dissipated. 

OlL-SuGARS. 

Oleosacchara,  N.  F.,  are  directed  to  be  made  by  triturating  2 
mils  (Cc.)  of  the  volatile  oil  with  100  Gm.  sugar. 

OINTMENT  (SIMPLE). 

Unguentum.  20  percent,  white  wax.  with  benzoinated  lard. 
Ointment  base,  Emollient. 

®  Ointment  Acid  Boric,  Squibb  jar,  lb.         ;  1-oz.  tubes 

Unguenium  Acidi  Borici.  10  percent,  boric  acid,  5  paraffin, 
85  white  petrolatum.  Antiseptic  Vulnerary. 

OINTMENT  ACID  CARBOLIC.     See  Ointment  Phenol. 

OINTMENT  ACID  TANNIC. 

Unguenium  Acidi  Tannici.  Simple  ointment,  with  20  percent, 
each  tannic  acid  and  glycerin.  Astringent,  Antiseptic. 

OINTMENT,  BASILICON.     See  Cerate  Rosin. 

©  Ointment  Belladonna,  Squibb  jar,  lb. 

Unguenium  Belladonna.  10  percent,  extract  belladonna  leaves, 
with  wool-fat  and  benzoinated  lard.  Anodyne. 


This  house  supplies  only  one  quality  of  each  product:  that  best 
suited  to  the  purposes  intended.  The  specification  "Squibb's" 
is  not  open  to  various  interpretations;  it  has  a  plain,  posi- 
tive meaning.  Therefore,  when  prescribing,  specify  SQUIBB'S. 


178        SQUIBB'S  MATERIA  MEDICA 

Ointment,   Blue.         See  Ointment  Mercury  Diluted. 

OINTMENT,  BROWN. 

Unguenlum  Fuscum,  N.  F.;  Mother's  Salve.  50  percent,  cam- 
phorated brown  plaster,  25  olive  oil,  25  suet.  Antiphlogistic, 
Discutient;  in  cellulitis,  felons,  boils,  etc. 

OINTMENT  CALAMINE. 

Unguenlum  Calaminat,  N.  F.;  Turner's  Cerate.  17  percent, 
calamine,  with  simple  ointment.  Drying  Antiseptic. 

OINTMENT  CAMPHOR. 

Unguenlum  Camphorce,  N.  F.  22  percent,  camphor,  with  white 
wax  and  lard.  Antipruritic,  Anodyne. 

OINTMENT  CARBOLIC  ACID.     See   Ointment  Phenol. 

®  OINTMENT  CHRYSAROBIN. 

Unguenlum  Chrysarobini.  6  percent,  chrysarobin,  with  ben- 
zoinated lard.  Antiparasitic.  Should  not  be  used  on  large 
surfaces;  toxic! 

Ointment,   Citrine.        See  Ointment  Mercury  Nitrate. 

Ointment   Diachylon,   Squibb  jar,  Ib. 

Unguenlum  Diachylon  ;  Hebra's  Lead  Ointment.  50  percent,  lead 
plaster,  49  white  petrolatum,  1  oil  lavender.  Astringent  Dermic. 

Ointment,  Hebra's  Itch.        See  Ointment  Sulphur  Compound. 
Ointment,   Hebra's   Lead.     See  Ointment  Diachylon. 

OINTMENT  IODINE. 

Unguenlum  lodi.  4  percent,  each  iodine  and  potassium  iodide, 
with  glycerin  and  benzoinated  lard.  Discutient.  Should  not  be 
dispensed  unless  recently  prepared. 

OINTMENT  IODOFORM. 

Unguenium  lodoformi.  10  percent,  iodoform,  with  benzoin- 
ated lard.  Vulnerary. 

OINTMENT  LEAD  IODIDE.            jar,  Ib.  ;  Vz  Ib.         ;  '/4  Ib. 

Unguenium    Plumbi   lodidi,    N.    F.  10    percent,    lead    iodide, 

with  benzoinated  lard.  Discutient,  in  indolent  ulcers,  swollen 
glands,  etc. 

0  Ointment  Mercury,  Squibb  jar  Ib.         ;  %  Ib. 

Unguentum  Hydrargyri ;  Mercurial  Ointment.  Mercury  50%, 
suet  35,  lard  15.  While  the  mercury  content  is  as  U.  S.  P. 
demands,  a  deviation  from  official  formula  has  been  made,  to 
produce  a  better  product.  The  oleate  of  mercury  officially  pre- 
scribed for  extinguistimg  the  mercury  is  omitted,  as  special  ap- 
paratus accomplishes  the  desired  result  more  effectually.  As 
the  rapid  absorption  of  the  mercury  depends  upon  the  fineness 
of  subdivision,  this  mercurial  ointment  will  be  found  to  give 
particularly  quick  and  reliable  results.  Endermic  Antisyphilitic. 
Dose  (by  inunction)  :  1  drachm  (4  Gm.),  night  and  morning. 


SQUIBB'S  MATERIA  MEDICA        179 

©  Ointment  Mercury  Diluted,  Squibb 

jar,  Ib.          ;  j/j  Ib.          ;  '/2'oz-  tubes, 

Unguentum  Hydrargyri  Dilutum;  Blue  Ointment.  A  thorough- 
ly effected  combination  containing  30  percent,  of  metallic  mer- 
cury (as  against  33  percent,  in  U.S.P.  VHIth  Rev.).  Anti- 
parasitic,  Antiluetic.  Dose  (by  inunction):  P/2  drachms  (6 
Gm.)  twice  daily. 

©  OINTMENT  MERCURY  AMMONIATED. 

Unguenium  Hydrargyri  Ammoniali ;  Ointment  White  Precipi- 
tate. 10  parts  ammoniated  mercury,  50  white  petrolatum,  40 
hydrous  wool- fat.  Antiparasitic  Dermic.  % 

Ointment   Mercury   Ammoniated,   2°/0,   Squibb 

l/g-oz.  tubes,  per  doz. 

OINTMENT  MERCURY  CHLORIDE  CORROSIVE,  SPREAD.    See  Mulls. 

Ointment  Mercury  Nitrate,  Squibb  jar,  Ib.  ;  %  Ib. 
Unguenium  Hydrargyri  Nilralis;  Citrine  Ointment.-  This 
ointment  will  become  comparatively  hard  in  consistence  on  keep- 
ing, but  practically  no  reduction  of  the  mercuric  nitrate  takes 
place.  Hardening  of  this  ointment  is  evidence  of  formation 
of  solid  elaidin,  and  therefore  proof  of  the  purity  of  the  ma- 
terials used.  It  only  requires  gentle  warmth  or  addition  of  a 
few  drops  of  lard  oil  to  bring  it  into  a  condition  to  be  readily 
dispensed.  Antiparasitic  Dermic;  in  tinea  capitis,  impetigo, 
psoriasis,  porrigo,  etc. 

OINTMENT  MERCURY  OXIDE  RED. 

Unguentum  Hydrargyri  Oxidi  Rubri,  N.  F.;  Red  Precipitate 
Ointment.  10  percent,  red  oxide  mercury,  with  hydrous  wool- 
fat  and  petrolatum.  Stimulant  Vulnerary,  Parasiticide;  in  eye 
diseases,  indolent  ulcers,  etc. 

©  Ointment  Mercury  Oxide  Yellow,  Squibb 

jar,  Ib.          ;  %  Ib. 

Unguentum  HyJrargyri  Oxidi  Flavl;  Yellow  Precipitate  Oint- 
ment. 10  percent,  yellow  oxide  of  mercury,  with  wool-fat  and 
petrolatum.  In  The  Squibb  Laboratories  this  ointment  is  made 
by  precipitating  a  very7  finely  divided  yellow  oxide  of  mercury 
from  a  solution  of  mercuric  chloride.  The  precipitate  is 
washed  until  it  is  free  from  chlorides,  and  the  moist  magma 
is  used  in  preparing  the  ointment.  This  process  has  the 
advantage  of  yielding  an  ointment  in  which  the  oxide  is  in 
an  extremely  finely  divided  state,  a  condition  not  obtainable 
when  the  dry  chemical  is  used,  regardless  of  the  method  by 
which  the  dry  salt  may  have  been  produced.  Stimulant  Anti- 
septic, chiefly  in  eye  diseases. 


The  prices  of  the  Squibb  Products  are  ir»  all  instances  as  low  as 
the  quality  and  quantity  of  ingredients  and  the  expense  of  man- 
ufacture allow.  They  include  containers,  packing  and  boxing.  When 
ordering  or  prescribing  medicinal  products,  specify  SQUIBB'S. 


180        SQUIBB'S  MATERIA  MEDICA 

Ointment  Mercury  Oxide  Yellow  1  % ,  Squibb 

J/g-oz.  collapsible  tubes,  each  in  wooden  case,  per  doz. 
Made  from  freshly  precipitated  mercuric  oxide  in  the  colloidal 
state;   not  from  powder  form  of  chemical.     It  contains  latter  in 
extremely  fine  form  and  thoroughly  incorporated  in  a  bland  base. 
Ophthalmic   Discutient. 

Ointment  Mercury  Oxide  Yellow,  2%,  Squibb 

]/$-oz.  collapsible  rubes,  each  in  wooden  case,  per  doz. 

OINTMENT  NUTGALL. 

Unguentum  CaAce;  Ointment  Galls.  20  percent,  powdered 
nutgall,  in  simple  ointment.  Astringent;  in  hemorrhoids,  pro- 
lapsus ani,  flabby  ulcers,  etc. 

OINTMENT  PHENOL. 

Unguentum  Phenolis ;  Ointment  Carbolic  Acid.  2J/£  percent, 
liquefied  phenol,  with  simple  ointment.  Wound  Antiseptic, 
Antipruritic. 

OINTMENT  POTASSIUM  IODIDE. 

Unguentum  Potassii  lodidi,  N.  F.  Dropped  from  U.  S.  P.  10 
percent.,  with  1  percent,  sodium  thiosulphate,  in  benzoinated 
lard.  Discutient,  Alterative;  in  scrofulous  tumors,  goitre,  etc. 

OINTMENT  RED  PRECIPITATE.     See  Ointment  Mercury  Oxide  Red. 

Ointment  Resorcinol  (Resorcin)  Compound,  Squibb 

jar,  Ib.          ;  %  Ib. 

Unguenlum  Resorcinolis  Compositum,  N.  F.  6  percent,  each 
resorcinol,  zinc  oxide,  bismuth  subnitrate,  and  rectified  oil  birch 
tar,  with  yellow  wax,  petrolatum,  glycerin  and  wool-fat.  Anti- 
septic and  Astringent  Dermic. 

OINTMENT  ROSE  WATER. 

Unguentum  Aqua  Rosas.  Spermaceti  12.5  percent.,  white 
wax  12,  expressed  oil  almond  56,  borax  0.5,  stronger  rose 
water  19.  Emollient;  Ointment  Base. 

OINTMENT  SALICYLATED  CREOSOTE.  See  under  Mulls. 
OINTMENT  SALICYLIC  ACID,  SPREAD.  See  under  Mulls. 
OINTMENT,  SIMPLE.  See  Ointment. 

OINTMENT  STRAMONIUM. 

Unguenlum  Stramonii.  10  percent,  extract  stramonium,  with 
wool-fat  and  benzoinated  lard.  Anodyne;  in  irritable  ulcers, 
painful  hemorrhoids,  etc. 

0  Ointment  Sulphur,  Squibb  jar.  Ib. 

Unguenlum  Sulphuris.  15  percent,  sublimed  sulphur,  with 
benzoinated  lard.  Anliparasilic,  especially  in  scabies. 


SQUIBB'S  MATERIA  MEDICA        181 

OINTMENT  SULPHUR  ALKALINE. 

Uneuentum  Sulphuris  Alfyalinum,  N.  F.  20  percent,  sublimed 
sulphur,  10  percent,  potassium  carbonate,  with  benzoinated  lard. 
Antiparasitic,  Antipruritic  Dermic. 

Ointment  Sulphur  Compound,  Squibb  jar,  lb. 

Wilkinson's  Ointment;  Hebra's  Itch  Ointment.  Practically 
Unguenium  Sulphuris  Composilum,  N.  F.,  but  made  with  wool- 
fat  instead  of  lard.  This  modification  prevents  separation  of 
the  water  contained  in  the  soft  soap,  and  thus  yields  a  smooth 
and  permanent  ointment.  Combination  of  precipitated  calcium 
carbonate  (10),  sublimed  sulphur  (15),  oil  cade  (15),  soft 
soap  (30),  and  anhydrous  wool-fat  (30).  Antiparasitic,  Anti- 
pruritic Dermic;  especially  in  scabies. 

OINTMENT  TAR. 

Unguenium  Picis  Liquids.  Tar,  50  percent.;  yellow  wax,  15; 
lard,  35.  Antiparasitic  Dermic;  in  tinea  capitis,  psoriasis,  etc. 

OINTMENT  TAR  COMPOUND. 

Unguenium  Picis  Compositum,  N.  F.  Prepared  from  oil  tar 
(4  percent.),  tincture  benzoin  (2  percent.),  zinc  oxide  (3  per- 
cent), yellow  wax,  lard  and  cotton-seed  oil.  Antipruritic,  Anti- 
septic Dermic;  chiefly  in  ringworm,  prurigo,  chronic  eczema. 

OINTMENT  VERATRINE. 

Unguentum  Veralrms,  N.  F.;  dropped  from  U.  S  P.  4  per- 
cent, veratrine,  6  expressed  oil  almond,  with  benzoinated  lard. 
Counter-irritant,  Anodyne.  Use  carefully;  toxic! 

OINTMENT   WHVTE    PRECIPITATE.     See    Ointment    Mercury   Am- 
moniated. 

Ointment,    Wilkinson's.         See  Ointment  Sulphur  Compound. 

Ointment     Yellow     Precipitate.       See    Ointment    Mercury 
Oxide  Yellow. 

OINTMENT  ZINC  CARBONATE  CRUDE.     See  Ointment  Calamine. 

©  Ointment  Zinc  Oxide,  Squibb 

jar,  lb.          ;  1-oz.  tubes, 

Made  from  special  lead-free  and  arsen-free  zinc  oxide. 
Strength  of  official  Unguenium  Zinci  Oxidi,  20  percent.,  but 
containing  white  petrolatum  as  base  instead  of  benzoinated 
lard;  latter  causes  ointment  to  become  granular  in  appearance 
and  rancid  on  long  keeping.  Antiseptic  Astringent  and  Dermic 
Sedative;  in  inflammatory  cutaneous  diseases,  chronic  ophthalmia, 
etc. 


|f  difficulty  is  experienced  in  procuring  any  Squibb  product, 
in  the  original  packages  here  listed,  please  notify  us ;  we 
shall  see  that  your  wants  are  met  promptly  and  satisfactorily. 


182        SQUIBB'S  MATERIA  MEDICA 

OINTMENT  ZINC  STEARATE. 

Unguentum  Zinci  Stearatis,  N.  F.  Equal  parts  zinc  slearate  and 
white  petrolatum.  Antiseptic  Emollient  and  Protective  Dermic. 

Oleates.  —All  oleates  change  on  long  keeping,  more  rapidly 
when  exposed.  Therefore  it  is  advisable  to  purchase  in  small 
quantities  and  frequently.  The  oleic  acid  we  employ  is  par- 
ticularly free  from  stearic  acid.  Hence  the  oleates  of  the  Squibb 
Laboratories  are  very  quickly  absorbed  and  do  not  produce  the 
disagreeable  greasiness  attending  the  use  of  ordinary  oleates. 

OLEATE  ACONITINE. 

Olealum  Aconitin<e,  N.  F.  2  percent.  Local  Anodyne;  in 
neuralgia,  painful  joints,  etc.  Avoid  abraded  surfaces. 

OLEATE  ATROPINE. 

Oleatum  Alropince,  N.  F.  2  percent,  atropine,  in  mixture  of 
about  equal  parts  oleic  acid  and  olive  oil.  Anodyne,  Anti- 
spasmodic  ;  in  whooping-cough,  etc. 

COCAINE. 


Oleatum  Cocaines,  N.  F.,  5  percent,  cocaine.  Local  Anes- 
thetic. 

Oleate  Mercury,  Squibb  bottle,  |4  Ib.         -,  oz. 

Olealum  Hydrargyri.  25  percent,  yellow  mercuric  oxide. 
Antiluetic,  Alterative;  in  syphilitic  and  scrofulous  inflammations. 

Oleate  Quinine,  Squibb  bottle,  J4  Ib.         ;  oz. 

Oleatum  Quinince,  N.  F.;  25  percent,  quinine.  Antiperiodic, 
by  inunction. 

OLEATE  VERATRINE. 

Oleatum  Vefatrlns,  N.  F.;  2  percent,  veratnne,  in  mixture  of 
about  equal  parts  oleic  acid  and  olive  oil.  Rubefacient,  Ano- 
dyne; in  scrofulous  joints,  sprains,  etc. 

Oleoresin    Aspidium,    Squibb  bottle,  oz. 

Oleoresina  Aspidii;  Oleoresin  or  Extract  Male  Fern.  It 
usually  shows  a  crystalline  deposit  of  filicic  acid  on  standing, 
and  in  such  cases  should  be  well  shaken  before  dispensing. 
Thick,  olive-green  liquid;  bitter,  disagreeable  taste.  Anthel- 
mintic.  Average  Dose:  according  to  U.  S.  P.,  30  grains  (2 
Gm.).  Some  authorities  recommend  in  taenia  solium  (the  usual 
kind  of  tapeworm),  2J/2  to  3  fluidrachms  (10  to  12  mils  [Cc.]) 
in  3  portions  half  an  hour  apart,  in  capsules,  followed,  if  neces- 
sary, in  2  hours  by  a  cathartic,  avoiding  castor  oil,  however. 

Oleoresin  Capsicum,  Squibb  bottle,  oz. 

Oleoresina  Capslcl;  Oleoresin  Red,  Spanish  or  Cayenne  Pep- 
per. Rubefacient  externally;  Carminative  and  Gastric  Stimu- 
lant internally.  Usually  applied  diluted  with  soap  liniment  or 
oil;  in  lumbago,  neuralgia,  etc.  Average  Dose:  J/2  grain  (0.03 
Gm.). 


SQUIBB'S  MATERIA  MEDICA-       183 

Oleoresin  Cubeb,  Squibb  bottle,  oz. 

Oleoresina  Cubebce.  Expectorant,  Anticatarrhal ;  in  bronchitis 
and  genito-urinary  diseases.  Average  Dose :  8  grains  (0.5  Cm.) . 
NOTE:  Oleoresin  Cubeb,  on  long  standing,  may  deposit  a  waxy, 
crystalline  substance;  this  the  U.  S.  P.  directs  to  be  rejected, 
the  liquid  portion  only  being  used. 

Oleoresin  Ginger,  Squibb  bottle,  oz. 

Oleoresina  Zingiberis.  From  best  quality,  peeled  Jamaica 
ginger.  Carminative,  Stimulant.  Average  Dose :  Yi  grain 
(0.03  Gm.). 

OLEORESIN  LUPULIN. 

Oleoresina  Lupuhni,  N.  F.  Bitter  Tonic;  also  used  as  Nerve 
Sedative  and  Antispasmodic,  in  nervousness,  bladder  irritation, 
etc.  Average  Dose:  3  grains  (0.2  Gm.). 

Oleoresin    Male     Fern.      See   Oleoresin   Aspidium. 

OLEORESIN  PARSLEY  FRUIT. 

Oleoresina  Pelroselini;  Liquid  Apiol.  Greenish,  oily  liquid. 
Soluble  in  alcohol,  chloroform  or  ether;  insoluble  in  water. 
Emmenagogue,  Antiperiodic.  Average  Dose :  8  minims  (0.5 
mil  [Cc.]),  in  capsules. 

OLEORESIN-  PEPPER. 

Oleoresina  Piperis.  Carminative,  Stimulant;  adjuvant  to  anti- 
pyretics and  tonics.  Average  Dose:  1/o  grain  (0.03  Gm.). 

f  OPIUM. 

Opium;  Gum  Opium.  Air-dried,  milky  exudation  obtained  by 
incising  unripe  capsules  of  Papaver  somniferum  and  its  variety 
album  (Fam.  P  ap  aver  ace  d).  Irregular,  rounded,  somewhat 
flattened  masses  or  cakes;  grayish-brown  externally,  dark-brown 
internally,  plastic  when  fresh,  of  strong,  narcotic  odor,  and 
bitter  taste.  Assays  not  less -than  9.5  percent,  anhydrous  mor- 
phine. Analgesic,  Cerebrospinal  Depressant,  Antispasmodic, 
Antiphlogistic.  Average  Dose:  1  grain  (0.06  Gm.).  Antidotes: 
potassium  permanganate  (2  grains  in  solution),  emetics;  atro- 
pine  or  strychnine  hypodermically ;  hot  strong  coffee;  exercise. 
(See  also  Extract;  Tincture;  Tablets  [Part  II].) 

f  OPIUM  DEODORIZED. 

Opium  Deodoralum;  Denarcotized  Opium.  Assays  10  to  10.5 
percent,  anhydrous  morphine.  Action  like  that  of  opium,  with- 
out narcotic  effect.  Average  Dose:  1  grain  (0.065  Gm.). 
Antidotes :  as  of  opium. 


The  Squibb  products  are  recognized  everywhere  as  the  Quality 
Standard.  They  are  of  uniform  purity  and  strength,  hence 
theraupeutically  dependable.  When  ordering  or  prescribing  medi- 
cinal products,  you  will  do  well  always  to  specify  SQUIBB'S. 


184       SQUIBB'S  MATERIA  MEDICA 

• 

f  Opium   Granulated,   Squibb  bottle,  oz. 

Opium  Granulaium.  Assays  10  to  10.5  percent,  anhydrous 
morphine.  Used  for  making  tincture  opium  and  tincture  de- 
odorized opium. 

t  0  Opium  Powdered,  Squibb  bottle,  oz. 

Opu  Pulvis.  Assays  10  to  10.5  percent,  anhydrous  morphine 
(equivalent  to  10.64  to  11.17  percent,  crystallized  morphine), 
as  against  12  to  12.5  percent,  crystallized  morphine  in  U.  S.  P. 
VII I th  Rev.  Average  Dose:  1  grain  (0.065  Gm.).  Antidotes: 
see  opium. 

Opodeldoc,  Liquid.          See  Liniment  Soap. 

OPODELDOC,  SOLID.     See  Liniment  Soap  Camphorated. 

ORANGE  PEEL,  BITTER. 

A  ur an  til  Amari  Corlex.  Dried  rind  of  unripe  fruit  of  Citrus 
Aurantium  amara  (Fam.  Rutaceae).  Aromatic  Bitter  Stom- 
achic; flavoring  agent.  Average  Dose:  15  grains  (1  Gm.). 

ORANGE  PEEL,  SWEET. 

Aurantii  Dulcis  Cortex.  Outer  rind  of  fresh,  ripe  fruit  of 
Citrus  Aurantium  sinensis  (Fam.  Rutacea).  Flavoring  agent. 
(See  also  Fluidextract;  Tincture.) 

ORPHOL.      Brand   of    Bismuth    Betanaphtholate. 

ORRIS  ROOT. 

Iris,  N.  F.  Rhizome  of  Iris  florentina,  /.  germanica,  or  /.  pal* 
lida  (Fam.  Iridacets),  peeled  and  dried.  Violet-like  odor; 
slightly  aromatic,  bitterish  taste.  Masticatory;  used  largely 
in  perfumery  and  tooth  powders. 

ORTHOFORM. 

Orthoform  New.  Methyl  Metaamidoparaoxybenzoate.  CeHa.- 
NH2.OH.CO.O.CH3.  White,  inodorous,  tasteless,  neutral 
powder.  Soluble  in  6  parts  alcohol,  50  ether;  sparingly  in 
water.  Local  Anesthetic,  Analgesic.  Dose:  8  to  15  grains 
(0.5  to  1  Gm.).  Used  topically  pure  or  with  milk  sugar, 
or  as  ointment. 

OuABAIN. 

Crystallized  Strophanthin;  G-Strophanthin.  CsoH46Oi2.9H2O. 
Glucoside  from  Acocanthera  ouabaio,  or  as  now  commonly  pre- 
pared, from  Strophanthus  gratus.  Colorless,  bitter  crystals. 
Soluble  in  about  100  parts  water  or  alcohol;  slightly  in  ether 
or  chloroform.  Used  in  place  of  Strophanthus  or  strophanthin 
as  substitute  for  digitalis,  by  intramuscular  or  intravenous  in- 
jection. Dose:  Vl20  §ra'n  (0.0005  Gm.)  once  in  24  hours. 

OVARY  SUBSTANCE,  DRIED. 

1  Gm.  represents  about  6  Gm.  fresh  gland.  Yellowish  powder; 
peculiar  odor.  Partially  soluble  in  water.  Alterative,  in  dis- 
orders following  menopause.  Dose:  1  to  3  grains  (0.06  to  0.2 
Gm.)  three  times  daily. 


SQUIBB'S  MATERIA  MEDICA        185 

OXGALL. 

Pel  Bovis.  Fresh  bile  of  the  ox,  Bos  taurus  (Fam.  Bovidy). 
Brownish-green  or  dark-green,  somewhat  viscid  liquid;  peculiar 
odor;  disagreeable,  bitter  taste;  sp.  gr.  1.015  to  1.025.  Used 
for  making  extract  of  and  purified  oxgall.  (See  these  titles.) 

®  Oxgall  Purified,  Squibb 

*  Pilular  glass  jar,  oz. 

Powdered  bottle,  oz. 

Pel  Bovis  Purification,  U.  S.  P.  VHIth  Rev.;  Purified  Oxgall; 
Inspissated  Oxgall;  Pel  Tauri  Purificatum.  Fresh  ox-bile, 
purified  with  alcohol  and  concentrated  to  pilular  consistence,  or 
dried  and  reduced  to  powder.  Yellowish-green,  soft  solid,  or 
powder;  peculiar  odor,  partly  sweet  and  partly  bitter  taste. 
Freely  soluble  in  water  or  alcohol.  Intestinal  Antiseptic, 
Cholagogue,  Laxative;  in  typhoid  fever,  intestinal  indigestion, 
deficient  biliary  secretion,  etc.  Dose:  5  to  10  grains  (03  to 
0.65  Cm.),  in  capsules  or  tablets.  (See  also  Tablets  [Part 
II].). 

®  OXYGEN. 

Oxygem'um,  O.  Colorless,  odorless,  tasteless  gas.  Soluble  in 
34  volumes  water,  3.6  alcohol.  Antidyspneic,  Sustenant;  in 
asphyxia,  carbon  monoxide  poisoning,  etc. 

OXYMEL  SQUILL. 

Oxymel  Scillai,  N.  F.  50  percent,  vinegar  squill,  with  clari- 
fied honey.  Expectorant,  Emetic.  Average  Dose:  1  fluidrachm 
(4  mils  [Cc.]);  children's  Emetic,  I  fluidrachm,  at  short  in- 
tervals. Incompatible  with  alkaline  salts. 

0  Pancreatin,  Squibb          bottle,  Ib.         ;  %  Ib.         ;  oz. 

Pancrealinum.  Mixture  of  enzymes  naturally  existing  in  pan- 
creas of  warm-blooded  animals,  and  obtained  from  fresh  pan- 
creas of  the  hog  (Sus  scrofa)  or  the  ox  (Bos  taurus).  It  contains 
principally  amylopsin,  trypsin  and  steapsin,  and  under  pharma- 
copoeial  conditions  is  capable  of  converting  not  less  than  25 
times  its  own  weight  of  starch  into  substances  soluble  in  water; 
also  digests  casein  of  milk  and  emulsifies  fats.  Cream-colored, 
amorphous  powder;  faint,  not  unpleasant  odor;  meat-like  taste. 
Slowly  and  incompletely  soluble  in  water;  insoluble  in  alcohol. 
Digestive;  used  largely  for  predigestion  of  protein  and  starchy 
foods.  Incompatible  with  pepsin,  mineral  acids  in  greater 
concentration  than  0.5  percent.,  concentrated  alkalies,  alcohol. 
Average  Dose:  8  grains  (0.5  Cm.). 

Since  we  make  only  one  quality  of  each  product,  that  best 
suited  to  the  purposes  intended,  the  specification  "Squibb's" 
is  not  open  to  various  interpretations,  but  has  a  plain,  positive 
meaning.  When  ordering  or  prescribing,  specify  SQUIBB'S. 


186        SQUIBB'S  MATERIA  MEDICA 

f  PANTOPON. 

Mixture  of  hydrochlorides  of  opium  alkaloids  as  found  in 
»  opium.  Assays  50  percent,  anhydrous  morphine  hydrochloride. 
Yellowish-gray,  bitter  powder.  Readily  soluble  in  water. 
Succedaneum  for  opium;  used  also  hypodermically.  Dose: 
Vl2  to  1/3  grain  (0.005  to  0.02  Gm.). 

PAPAIN. 

Papayotin;  Vegetable  Pepsin.  Digestive  principle  of  juice  of 
Carica  Papaya  (Papaw).  Acts  best  in  weak  alkaline  solu- 
tion. Whitish  powder.  Soluble  in  water  and  glycerin;  in- 
soluble in  alcohol,  chloroform,  ether.  Dose:  2  to  5  grains  (0.13 
to  0.3  Gm.),  with  sodium  bicarbonate.  Externally,  in  fissured 
tongue  and  diphtheria,  in  5  percent,  glycerino-aqueous  solution. 

Paper,  Litmus.         See  Litmus  Paper. 

PAPER,  POTASSIUM  NITRATE. 

Charta  Potassii  Nilratis,  N.  F.  Strips  of  paper  soaked  with 
20%  solution  potassium  nitrate  and  dried.  Burned,  and  fumes 
inhaled  in  paroxysms  of  asthma. 

Paprika  Powdered,  Squibb  tin  Ib.         ; 

4-oz.  sifter-top  tins,  per  doz.          ; 

2-oz.  sifter-top  tins,  per  doz.          ; 

1  -oz.  sifter-top  tins,  per  doz. 

A  variety  of  red  pepper  largely  employed  as  spice;  less  pun- 
gent and  of  richer  flavor  than  capsicum. 

PARACOTO. 

Paracoto,  N.  F. ;  Goto.  Bark  of  unidentified  tree  indigenous  to 
Northern  Bolivia.  Strong  odor;  pungent,  nutmeg-like  taste. 
Intestinal  Astringent.  Average  Dose:  5  grains  (0.3  Gm.). 
(See  also  Fluidextract.) 

0  PARAFFIN. 

Paraffinum.  Purified  mixture  of  solid  hydrocarbons  from 
petroleum.  White,  odorless,  tasteless  mass.  Soluble  freely  in 
ether,  benzin,  carbon  disulphide,  volatile  oils;  insoluble  in 
water  or  alcohol.  Sp.  gr.  about  0.900;  melting-point  50°  to 
57°  C.  Used  in  surgery  for  prosthetic  purposes,  and  in  phar- 
macy for  raising  melting-point  of  ointments. 

Paraffin   Liquid.      See  Liquid  Petrolatum. 

PARA  FORM  ALDEHYDE. 

ParaformaldehyJum ;  Paraform;  Trioxymethylene.  (HCHO),3. 
White  friable  masses  or  powder;  slight  formaldehyde  odor. 
Slowly*  soluble  in  water;  insoluble  in  alcohol,  ether.  Intestinal 
Antiseptic,  Escharotic  (in  10  percent,  suspension  in  collodion). 
Used  chiefly  to  generate  formaldehyde  by  heating,  for  disin- 
fection. Average  Dose:  8  grains  (0.5  Gm.).  NOTE:  Its  in- 
ternal use  seems  inadvisable  since  it  has  produced  serious  results. 


SQUIBB'S  MATERIA  MEDICA        187 

0Paraldehyde,  Squibb.        bottle,  Ib.        ;  14  lb.          ;  oz. 

Paraldehydum.  C(jHi2O3.  Polymer  of  acetaldehyde.  Color- 
less, transparent  liquid;  strong,  pungent  odor;  burning,  cooling 
taste.  Sp.  gr.  about  0.990.  1  Gm.  dissolves  in  8  mils  (Cc.) 
water;  in  all  proportions  alcohol,  ether,  chloroform,  oils, 
Prompt,  fairly  active  Hypnotic  and  Sedative,  devoid  of  ser- 
ious side-effects;  in  nervous  insomnia,  alcoholism,  asthma,  in- 
sanity, etc;  Average  Dose:  30  minims  (2  mils  [Cc.]),  well 
diluted. 

PARATHYROID  GLAND  DRIED. 

1  Gm.  represents  6  Gm.  fresh  gland.  Light-yellow  powder; 
peculiar  odor.  Partially  soluble  in  water.  Antispasmodic, 
Nervine;  in  tetany  following  removal  of  parathyroid  glands, 
paralysis  agitans,  chorea,  etc.  Dose :  J/SO  to  VlO  grain  (0.003 
to  0.006  Gm.)  three  or  four  times  daily. 

Paregoric.        See  Tincture  Opium  Camphorated. 

PAREIRA. 

Parelra,  N.  F. ;  Pareira  Brava.  Dropped  from  U.  S.  P. 
Dried  root  of  Chondodendron  tomenlosum  (Fam.  Menisper- 
maceai).  Of  slight  odor;  bitter  taste.  Bitter  Tonic;  used  also 
as  Diuretic  and  Alterative.  Average  Dose:  30  grains  (2  Gm.). 

PARRISH'S    CAMPHOR    MIXTURE.      See    Mixture    Camphor    Aro- 
matic. 

PARSLEY  FRUIT 

Pelroselinum;  Parsley  Seed,  Dried  ripe  fruit  of  Pelroselinum 
salivum  (Fam.  Umbelliferce).  Used  as  Emmenagogue  in  form 
of  its  oleoresm. 

PARSLEY   ROOT. 

Pelroselini  Radix,  N.  F.  Dried  root  of  Pelroselinum  salivum 
(Fam.  Umbelliferce).  Aromatic  odor;  sweetish,  pungent  taste. 
Carminative.  Average  Dose:  30  grains  (2  Gm.). 

PASSION  FLOWER. 

Passiflora,  N.  F.  Dried  herb  of  Passiflora  incarnaia  (Fam. 
Passifloracecs).  Slight  odor  and  taste.  Used  in  insomnia. 
Average  Dose:  3  grains  (0.2  Gm.). 

PASTE  BETANAPHTHOL. 

Pasta  Betanaphtholis,  N.  F.;  Lassar's  Naphthol  Paste.  Beta- 
naphthol  10  percent.,  precipitated  sulphur  50,  petrolatum  20, 
soft  soap  20.  Antiparasitic,  Antipruritic  Dermic. 

PASTE,  DEXTRINATED. 

Pasta  Dextrinata,  N.  F.  White  dextrin  33  percent.,  glycerin 
33,  water  34.  Basis  for  dermatologic  pastes. 

The  founder  of  the  House  of  Squibb,  Dr.  Edward  R.  Squibb, 
not  only  had  high  ideals,  but  lived  and  labored  for  them;  and, 
in  the  words  of  William  Miller  Bartlett,  "the  House  of  Squibb 
stands  today  as  a  living  monument  to  the  honor,  integrity,  zeal 
and  devotion  of  its  founder." 


188       SQUIBB'S  MATERIA  MEDICA 

PASTE,  LONDON.     See  Soda  with  Lime. 

PASTE  PENCILS. 

Still  Dilubiles,  N.  F.,  Unna's  Paste  Pencils.  For  direct  appli- 
cation in  dermatological  practice.  Base  consists  of  starch, 
dextrin,  tragacanth,  sugar  and  water;  medicament,  10  percent. 

PASTE  RESORCINOL,  MILD. 

Pasta  Resorcinolis  Mills,  N.  F.;  Lassar's  Mild  Resorcin 
Paste.  Resorcin  10  percent.,  zinc  oxide  25,  starch  25,  light 
liquid  petrolatum  40. 

PASTE  RESORCINOL,  STRONG. 

Pasta  Resorcinolis  Fortis,  N.  F.;  Lassar's  Stronger  Resorcin 
Paste.  Resorcinol  20  percent.,  zinc  oxide  20,  starch  20,  light 
liquid  petrolatum  40.  Antiparasitic,  Astringent  Dermic. 

PASTE  SULPHURATED  ZINC. 

Pasta  Zinci  Sulphurala,  N.  F.;  Unna's  Sulphurated  Zinc 
Paste.  Zinc  oxide  15  percent.,  precipitated  sulphur  10,  purified 
siliceous  earth  5,  benzoinated  lard  70.  Siccative,  Antiparasitic 
Dermic. 

PASTE  ZINC. 

Pasta  Zinci,  N.  F.;  Lassar's  Zinc  Paste.  Salicylic  acid  2 
percent.,  zinc  oxide  24,  starch  24,  petrolatum  50.  Astringent, 
Antiseptic  Dermic. 

PASTE  ZINC,  SOFT. 

Pasta  Zinci  Mollis,  N.  F.;  Unna's  Soft  Zinc  Paste.  Zinc 
oxide,  precipitated  calcium  carbonate,  linseed  oil,  lime  water; 
each  25  percent.  Astringent,  Drying  Dermic. 

0  PELLETIERINE  TANNATE. 

PelletierincB  T annas ;  Punicine  Tannate.  Natural  mixture  of 
tannates  of  four  alkaloids  from  pomegranate.  Light-yellow, 
odorless,  amorphous  powder;  astringent  taste.  1  Cm.  dissolves 
in  240  mils  (Cc.)  water,  16  alcohol,  420  ether;  insoluble  in 
chloroform.  Anthelmintic.  Average  Dose:  4  grains  (0.25 
Gm.). 

PELLITORY  ROOT.     See  Pyrethrum. 

Pepper,  Black,  Squibb  Whole  tin,  lb. 

*Powdered  tin,  lb. 

sprinkler-top  tins,  4-oz.,  per  doz. 

2-oz.,  per  doz.          ;  1-oz.,  per  doz. 

Piper.  Dried  unripe  fruit  of  Piper  nigrum  (Fam.  Pi'peracete). 
First  quality,  absolutely  unsophisticated.  Contains  1  to  2  per- 
cent, volatile  oil.  Condiment;  Carminative,  Stomachic,  to  relieve 
flatulence  and  excite  gastric  digestion.  Average  Dose:  8 
grains  (0.5  Gm.). 


SQUIBB'S  MATERIA  MEDICA        189 

Pepper,  Cayenne.       See  Pepper,  Red. 

®  Pepper,  Red,  Squibb  tin  Ib. 

(Powdered)  sprinkler-top  tins,  4-oz.,  per  doz. 

2-oz.,  per  doz.          ;  1  -oz.,  per  doz. 

Capsicum;  Red,  Pod,  Spanish  or  Cayenne  Pepper.  Dried  ripe 
fruit  of  Capsicum  frutcscens  (Fan.  Solanaceaz).  Best  African 
capsicum,  called  "African  Bird  Pepper,"  purchased  upon  chem- 
ical assay,  the  yield  of  oleoresin  being  approximately  20  percent. 
Rubefacient  externally;  Stimulant  Stomachic,  Condiment,  in- 
ternally. Average  Dose:  1  grain  (0.065  Gm.). 

Pepper,   Spanish.         See   Pepper,   Red. 

Pepper,  Special  Blend,  Squibb  tin  Ib. 

(Powdered)  '/4-lb.  sifter-top  tins,  per  dozen, 

2-oz.  sifter-top  tins,  per  dozen, 
1  -oz.  sifter-top  tins,  per  dozen,       ^ 

A  carefully  adjusted  blend  of  white  and  black  peppers  produc- 
ing an  article  of  distinctive  flavor  different  from  that  of  any 
of  the  ingredients  separately. 

Pepper,  White,  Squibb  tin,  Ib. 

(Powdered)  sprinkler-top  tins,  4-oz.,  per  doz. 

2-oz.,  per  doz.          ;  1  -oz.,  per  doz. 

Prepared  by  depriving  the  black  seed  of  its  outer  skin,  by 
soaking  in  water  and  rubbing.  The  berry  is  then  dried.  It 
has  less  of  the  peculiar  qualities  of  pepper  than  the  black 
berry.  Ordinary  Dose:  10  grains  (0.65  Gm.). 

®  PEPPERMINT. 

Mentha  Piperila.  Dried  leaves  and  flowering  tops  of  Mentha 
piperita  (Fan.  Labiata).  Carminative;  flavoring.  Average 
Dose:  60  grains  (4  Gm.).  (See  also  Oil;  Spirit.) 

0Pepsin  1:3000,  Squibb       bottle,  Ib.        ;  %  Ib.        ;  oz. 

*  Powder,  Scales  or  Granular 

Pepsinum.  Proteolytic  ferment  or  enzyme  obtained  from  glandu- 
lar layer  of  fresh  stomachs  of  healthy  pigs  (Sus  scrofa).  Capa- 
ble of  digesting  not  less  than  3,000  times  its  own  weight  of 
freshly  coagulated  egg  albumin,  under  the  conditions  outlined 
in  U.  S.  P.  Slightly  hygroscopic,  almost  odorless  scales  or 
grains,  or  white  or  cream-colored  powder,  without  offensive 
odor,  and  of  slightly  acid  or  saline  taste.  Soluble  almost  en- 
tirely in  about  50  parts  water,  more  freely  in  water  acidulated 
with  hydrochloiic  acid;  nearly  insoluble  in  alcohol,  chloroform, 
ether.  Digestive  internally;  Solvent  of  false  membranes  or 

The  Squibb  Ideals  have  taken  concrete  form  in  the  Squibb 
Products;  these  are  universally  recognized  as  standards  of 
uniform  Purity  and  Efficacy,  that  is,  general  Excellence  and 
Reliability.  Specify  SQUIBB'S  when  prescribing  or  ordering 


190        SQUIBB'S  MATERIA  MEDICA 

0  Pepsin,  1:3000,  Squibb  (Cont.) 

gangrenous  tissue,  externally.  Average  Dose :  8  grains  (0.5 
Gm.).  Incompatible  with  tannic  and  gallic  acids  and  their 
compounds;  much  alcohol;  alkalies  or  alkali  carbonates  and 
alkaline  earths;  and  it  should  not  be  prescribed  with  mineral 
acids  exceeding  0.5  percent,  in  strength.  (See  also  Essence; 
Glycerite;  Tablets  [Part  II].) 

Pepsin  Saccharated,  Squibb 

bottle,  Ib.          ;  |4  lb.          '•  oz- 

Pepsinum  Saccharatum,  N.  F.  10  percent,  pepsin,  with  sugar 
of  milk.  Average  Dose:  15  grains  (1  Gm.). 

PEPSIN,  VEGETABLE.    See  Papain. 

Peptone  Meat  Dry,  Squibb 

bottle,  Ib.          ;  '/4  Ib.  ;  oz. 

From   fresh,   lean  beef.      1    Gm.   represents    10  Gm.  lean   beef. 

Brown    powder,    or    light-brown    granules.      Soluble  in    water. 

Culture  medium  in  bacteriology;  Nutrient  in  gastric  ulcer,  etc. 
Dose:  30  to  60  grains  (2  to  4  Gm.). 

Peptonizing  Powder.        See  Powder  Pancreatin  Compound. 

Peptonizing  Tubes,  Squibb  box  of  12  tubes 

Each  contains  25  grains  compound  pancreatin  powder,  enough 
to  peptonize  1  pint  fresh  milk  according  to  directions  given 
on  label. 

Peruvian   Bark.       See  Cinchona. 

PETROLATUM  (YELLOW). 

Petrolatum;  Petroleum  Jelly;  Paraffin  Ointment.  Purified 
mixture  of  semi-solid  hydrocarbons  obtained  from  Petroleum. 
Yellowish  to  light-amber,  nearly  odorless  and  tasteless,  unctuous 
mass.  Sp.  gr.  0.820  to  0.865.  Readily  soluble  in  ether,  chloro- 
form, oil  turpentine.  Emollient,  Ointment  Base. 

PETROLATUM,  WHITE. 

Petrolatum  Album.  Preceding  article  wholly  or  nearly  de- 
colorized. 

Petrolatum   Liquid.      See  Liquid   Petrolatum. 
PETROLATUM  JELLY.     See  Petrolatum   (Yellow). 

PETROXOLIN,  LIQUID. 

Petroxolinum  Liquidum,  N.  F.;  Liquid  Petrox;  Petrolatum 
Saponatum  Liquidum,  N.  F.  III.  Light  liquid  petrolatum  sapon- 
ified with  ammonium  oleate  extemporaneously  made.  Yel- 
lowish-brown liquid,  miscible  with  ether,  chloroform  or  acetone, 
and  yielding  emulsion  with  2  volumes  water.  Penetrating  sol- 
vent vehicle  for  creosote,  iodine,  iodoform,  etc.,  for  endermic 
medication. 


SQUIBB'S  MATERIA  MEDICA        191 

PEXROXOLIN,  SOLID. 

Petroxolinum     Spissum,     N.     F.;  Solid     Petrox;      Petrolatum 

Saponatum    Spissum,    N.    F.    III.  Similar    to    preceding,    but 

semi-solid.     Ointment  vehicle,   for  endermic  medication. 

PETROXOLINS   (MEDICATED). 

With  two  exceptions,  solutions  in  liquid  petroxolin,  for  ender- 
mic medication.  Following  are  noted  in  N.  F.:  Petroxolin 
Betanaphthol,  10%;  Petroxolin  Cade,  25%;  Petroxolin 
Chloroform  Camphorated:  chloroform  25%,  camphor  25%; 
Petroxolin  Creosote,  20%;  Pelroxolin  Eucalyplol,  20%; 
Pelroxolin  Cuaiacol,  20%;  Petroxolin  Mercury:  13%  mer- 
cury, 13%  wool-fat,  2%  oleic  acid,  55%  solid  petroxolin; 
Petroxolin  Iodine,  10%;  Petroxolin  Iodine  Diluted,  5%; 
Petroxolin  lodoform:  3%  iodoform,  3%  eucalyptol;  Pelroxo- 
lin Menthol,  17%;  Pelroxolin  Methyl  Salicylate,  20%; 
Petroxolin  Phenol,  5%;  Pelroxolin  Phenol  Camphorated: 
12.5%  phenol,  37.5%  camphor;  Petroxolin  Tar:  25%  oil  tar; 
Petroxolin  Sulphur:  3%  sulphur;  Petroxolin  Sulphur  Com- 
pound: 10%  sulphur,  10%  oil  cade,  0.3%  thymol,  3%  eu- 
calyptol, 30%  oil  turpentine;  Petroxolin  Venice  Turpentine, 
20%. 

Phenacetin.          See  Acetphenetidin. 

Phenazone.         See  Antipyrine. 

Phenol   (Crystals),  Squibb  bottle,  Ib. 

Phenol;  Carbolic  Acid;  Phenic  or  Phenylic  Acid.  Hy- 
droxybenzene  obtained  from  coal-tar  or  synthetically.  Contains 
not  less  than  97  percent.  CfiHjOH.  1  Gm.  dissolves  in 
about  15  mils  (Cc.)  water;  freely  soluble  in  alcohol,  ether, 
choloform,  glycerin,  oils.  Antiseptic,  Germicide,  Local  An- 
aesthetic, Caustic;  also  Reagent.  Average  Dose:  1  grain  (0.065 
Gm.,)  in  pills  or  well  diluted.  Coagulates  collodion.  Tritu- 
rated with  acetanilid,  butyl-chloral  hydrate,  camphor,  mono- 
bromated  camphor,  chloral  hydrate,  lead  acetate,  menthol, 
naphthalene,  naphthol,  phenacetin,  pyrogallic  acid,  resbrcin, 
salol,  thymol,  urethane  or  terpin  hydrate,  phenol  yields  a 
liquid  or  a  soft  mass.  Antidotes :  alcohol  or  whiskey  freely  at 
once,  then  emetics;  soap;  siphonage  of  stomach;  soluble  sul- 
phates; demulcents. 

PHENOL' IODIZED. 

Phenol  lodatum,  N.  F.,  Iodized  Carbolic  Acid.  20  percent, 
iodine,  60  phenol,  20  glycerin.  Antiseptic,  Escharotic;  ap- 
plied pure. 


The  Squibb  Label  on  a  package  is  a  positive  guaranty  for  the 
uniform  Purity  and  Reliability  of  the  product.  We  make  only 
ONE  quality:  the  SQUIBB  quality;  and  our  prices  are  as  low 
as  they  can  be  made  for  that  quality.  Specify  SQUIBB'S. 


192        SQUIBB'S  MATERIA  MEDICA 

0  Phenol  Liquefied,  Squibb  bottle,  Ib.    . 

Phenol  Liquefaction;  Liquefied  Carbolic  Acid.  Crystalline 
product  liquefied  by  heat  and  adjusted  with  distilled  water  to 
strength  of  87  percent,  absolute  phenol.  Average  Dose:  1 
minim  (6.06  mil  [Cc.]). 

0  Phenolphthalein,  Squibb  bottle,  oz. 

Phenolphthaleinum ;  Dihydroxyphthalophenone.  C2oHi4C»4. 
White  or  yellowish-white,  crystalline  powder.  1  Gm.  dissolves 
in  13  mils  (Cc.)  alcohol,  70  ether;  almost  insoluble  in  water. 
Indicator;  latterly  recommended  as  an  agreeable,  tasteless 
mild  but  efficient  Laxative.  Average  Dose:  2'/2  grains  (0.15 
Gm.).  (See  also  Tablets  [Part  II].) 

Phenylacetamide.        See  Acetanilid. 

Phenyldimethylpyrazolon.        See  Antipyrin*. 

0  Phenyl  Salicylate,  Squibb 

carton,  Ib.          ;  ]4  Ib.          ;  oz. 

Phenylis  Salicylas;  Salol.  CisHioOs.  Nearly  white  powder; 
slight,  aromatic  odor  and  taste.  1  Gm.  dissolves  in  6670  mils 
(Cc.)  water,  6  alcohol;  very  soluble  in  ether,  chloroform,  and 
oils.  Intestinal  Antiseptic;  in  typhoid  fever,  fermentative 
dyspepsia,  grip,  cystitis,  etc.;  also  used  for  coating  enteric 
pills.  Average  Dose:  5  grains  (0.5  Gm.),  1  to  3  hours  after 
meals.  Incompatible  on  trituration  with  camphor,  monobro- 
mated  camphor,  chloral  hydrate,  phenol,  euphorin,  naphthalene, 
thymol,  or  urethane.  Keep  in  cool  place;  it  melts  at  about 
41°  C.  (105.8°  F.).  (See  also  Tablets  [Part  II].) 

0  PHOSPHORUS. 

Phosphorus.  P.  Translucent,  nearly  colorless  solid,  of  waxy 
luster;  disagreeable  odor  and  taste;  emits  fumes  on  exposure; 
often  takes  fire  spontaneously  on  long  exposure,  hence  must  be 
kept  under  water;  sp.  gr.  1.830  at  10°  C.  I  Gm.  dissolves  in 
about  400  mils  (Cc.)  dehydrated  alcohol,  17  chloroform,  102 
absolute  ether;  sparingly  soluble  in  fixed  oils;  almost  insol- 
uble in  water.  Stimulant  of  bone  formation,  rickets,  caries,  etc.; 
also  used  in  melancholia,  impotence,  etc.  Average  Dose:  1/ir>o 
grain  (0.0005  Gm.). 

0  PHYSOSTIGMA. 

Physostigma;  Calabar  Bean,  Dried  ripe  seeds  of  Physostigma 
"venenosum  (Fam.  Leguminosce) ,  yielding  not  less  than  0.15 
percent,  alkaloids.  Antitetanic,  Peristaltic,  Antifleuralgic. 
Average  Dose:  IJ/2  grains  (0.1  Gm.).  (See  also  Tincture.) 

Physostigmine,  Squibb  5-grain  vial 

Eserine.  CisFfolOjjNg.  Alkaloid  from  calabar  bean.  Color- 
less, very  hygroscopic  crystals,  upon  exposure  to  air  turning  to 
reddish  mass.  Soluble  in  alcohol,  ether,  chloroform.  Antite- 
tanic, Peristaltic,  Antineuralgic.  Ordinary  Dose:  ViU  grain 
(0.001  Gm.).  Antidotes:  emetics;  atropine  or  strychnine  sub- 
cutaneously;  pilocarpine;  chloral  hydrate;  stimulants. 


SQUIBB'S  MATERIA  MEDICA        193 

®  Physostigmine  Salicylate,  Squibb 

15-gr.  vial          ;  10-gr.  vial         ;  5-gr.  vial 

Physostigminai  Salicylas;  Eserine  Salicylate.  Ci.^HaiC^Ns.- 
C7H(jC>3.  Colorless  or  faintly  yellowish,  odorless  crystals; 
slightly  bitter  taste.  Reddens  on  exposure.  1  Gm.  dissolves  in 
75  mils  (Cc.)  water,  16  alcohol,  6  chloroform,  250  ether. 
Antitetanic,  Peristaltic,  Myotic;  in  tetanus,  strychnine 
poisoning,  neuralgia,  torpidity  of  bowels,  etc.  Average  Dose: 
i/64  grain  (0.001  Gm.).  Applied  to  eye  in  0.2  to  0.5  percent, 
solution. 

Physostigmine  Sulphate,  Squibb 

15  grains  ;  10  grains  *;  5  grains  ; 
3  grains,  ;  2  grains  ;  1  j/2  grains  ;  1  grain 
Physostigmirue  Sulphas,  U.  S.  P.  VHIth  Rev.;  Eserine  Sul- 
phate. (Ci5H2iO2N3)2.H2SO4.  White  or  yellowish  white, 
odorless,  bitter  powder.  Very  deliquescent;  prone  to  redden  pn 
keeping.  Soluble  in  1200  parts  ether;  freely  in  water,  alco- 
hol, chloroform.  Action,  uses,  etc.,  like  physostigmine  alkaloid. 
Applied  to  eye  in  0.2  to  0.5  percent,  solution. 

PHYTOLACCA. 

Phytolacca,  N.  F.;  Poke  Root.  Dried  root  of  Phytolacca  Je- 
candra  (Fam.  Phylolaccacecs) .  Average  Dose:  alterative,  l'/2 
grains  (0.1  Gm.) ;  emetic,  15  grains  (1  Gm.).  (See  also 
Fluidextract.) 

PILLS. 

We  formerly  offered  a  number  of  pills  at  the  time  used 
to  some  extent,  but  latterly  they  have  been  superseded 
largely  by  tablets,  so  that  we  have  discontinued  them  in 
favor  of  the  tablet  form.  Practically  all  of  them  will  be 
found  among  the  Tablets  in  Part  II  of  this  book.  The 
following  being  official  formulas,  are  here  described  for 
the  sake  of  reference: 

PILLS,  AIKEN'S  ToNIC.     See  Pills  Iron,  Quinine,  Strychnine  and 
Arsenic,  Mild. 

PILLS  ALOES. 

Pilulai  Aloes.  2  grains  each  aloes  and  soap.  Cathartic. 
Average  Dose:  2  pills. 

PILLS  ALOES  AND  ASAFETIDA. 

Pilul<e  Aloes  et  Asafcelida,  N.  F.  About  \Yf,  grains  each 
aloes,  asafetida,  soap.  Laxative  Nervine.  Average  Dose :  1 
pill. 


This  house  supplies  only  one  quality  of  each  product:  that  best 
suited  to  the  purposes  intended.  The  specification  "Squibb's" 
is  not  open  to  various  interpretations;  it  has  a  plain,  posi- 
tive meaning.  Therefore,  when  prescribing,  specify  SQUIBB'S. 

B 


194       SQUIBB'S  MATERIA  MEDICA 

PILLS  ALOES  AND  IRON. 

Pilules  Aloes  el  Fern,  N.  F.  1Vl2  grains  each  aloes,  dried 
iron  sulphate  and  aromatic  powder.  Laxative,  Emmenagogue. 

Average  Dose:  2  pills. 

PILLS  ALOES  AND  MASTIC. 

Pilules  Aloes  el  Masliches,  N.  F.;  Lady  Webster's  Dinner 
Pills.  2  grains  aloes,  with  about  %  grain  mastic;  J/2  grain 
rose.  Laxative,  Stomachic.  Average  Dose:  2  pills. 

PILLS  ALOES,  MERCURY  AND  PODOPHYLLUM. 

PilultE  Aloes,  Hydrargyri  el  Pockphylii,  N.  F.;  Triplex  Pills, 
N.  F.  III.  2  grains  aloes,  1  grain  mercury  mass,  '74  grain 
resin  poclophyllum.  Cholagogue  Cathartic.  Average  Dose :  1 
pill. 

PILLS  ALOES,  MERCURY  AND  SCAMMONY  COMPOUND. 

Pilules  Aloes,  Hydrargyri  el  Scammonii  Composiles,  N.  F.; 
Francis's  Triplex  Pills;  Pills  Scammony  Compound.  About  5/o 
grain  each  aloes,  resin  scammony,  and  mercury  mass;  1/2o  minim 
croton  oil;  J/4  minim  oil  caraway;  massed  with  tincture  aloes 
and  myrrh.  Drastic  Purgative,  Cholagogue.  Average  Dose: 
1  pill. 

PILLS  ALOES  AND  MYRRH. 

Pilule  Aloes  el  Myrrhcs,  N.  F.;  Rufus's  Pills.  Aloes  2 
grains,  myrrh  almost  1  grain,  aromatic  powder  2/^  grain.  Lax- 
ative, Carminative.  Average  Dose :  2  pills. 

PILLS  ALOES  AND  PODOPHYLLUM  COMPOUND. 

Pilules  Aloes  el  Podophylli  Composites,  N.  F. ;  Janeway's 
Pills.  1  grain  aloes,  ]/%  grain  resin  podophyllum,  '74  grain 
each  extracts  belladonna  leaves  and  nux  vomica.  Laxative. 
Average  Dose:  2  pills. 

PILLS  ALOIN  COMPOUND. 

Pilules  Aloini  Composites,  N.  F.  ]/2  grain  aloin,  J/g  grain 
resin  podophyllum,  !/4  grain  extract  belladonna  leaves.  Ca- 
thartic. Average  Dose:  1  pill. 

PILLS  ALOIN,  STRYCHNINE  AND  BELLADONNA. 

Pilulce  Aloini,  Strychnines  el  Belladonncs,  N.  F.  Contains  '75 
grain  aloin,  Vl-0  grain  strychnine,  J/g  grain  extract  belladonna 
leaves.  Tonic  Laxative.  Average  Dose:  1  pill. 

PILLS  ALOIN,  STRYCHNINE  AND  BELLADONNA  COMPOUND. 

Pilulce  Aloini,  Strychnines  el  Belladonncs  Composite,  N.  F. 
!/5  grain  aloin,  1/uo  grain  strychnine,  J/g  grain  extract  bella- 
donna leaves.  J/2  grain  extract  cascara  sagrada.  Tonic  Laxa- 
tive. Average  Dose:  1  pill. 

PILLS,    ANTIBILIOUS.      See    Pills    Cathartic    Compound. 


PILLS,  ANTIDYSPEPTIC. 

Pilules  Antidyspepticce,  N.  F.  ^40  grain  strychnine,  !/io  grain 
each  ipecac  and  extract  belladonna  leaves,  2  grains  each  mer- 
cury mass  and  compound  extract  colocynth.  Cholagogue, 
Tonic  Laxative.  Average  Dose:  1  pill. 

PILLS  ANTIMONY  COMPOUND. 

Pilulae  Antimonii  Composite,  N.  F.;  Plummer's  Pills.  About 
|^5  grain  each  sulphurated  'antimony  and  calomel,  V/4  grains 
guaiac,  massed  with  castor  oil.  Alterative,  Diaphoretic. 
Average  Dose:  1  pill. 

PILLS,  ANTIPERIODIC. 

Pilules  Anliperiodicce,  N.  F.;   Warburg's  Pills.     The  National 

Formulary  includes  the  following  two  modifications: 

With  Aloes:   1    grain  extract  aloes,  J/2  grain  each  rhubarb  and 

angelica,    J/4    grain    each    elecampane,    saffron    and    fennel,    J/g 

grain  each  zedoary,  cubeb,  myrrh,  white  agaric   and   camphor, 

12/5    grains    quinine    sulphate.      Average    Dose:    1    pill,    three 

times  daily. 

Without  Aloes:  same  as  preceding,  except  that  the  extract  aloes 

is  omitted.    Average  Dose:  1'pill,  three  times  daily. 

PILLS  ASAFETIDA. 

Pilulae  Asafostidae,  3  grains  asafetida.  Nerve  Sedative,  Anti- 
spasmodic;  in  hysteria,  whooping  cough,  asthma,  etc.  Average 
Dose:  2  pills. 

PILLS,  BLANCARD'S.    See  Pills  Iron  Iodide. 
PILLS,  BLAUD'S.     See  Pills  Iron  Carbonate. 

PILLS,  CATHARTIC  COMPOUND. 

Pilulae  Cathartics  Composites;  Antibilious  Pills.  V/4  grains 
compound  extract  colocynth,  about  1  grain  calomel,  J/3  grain 
resin  jalap,  J/4  grain  gamboge.  Average  Dose:  2  pills. 

PILLS,  CATHARTIC   VEGETABLE. 

Pilules  Catharlicce  Vegetables,  N.  F.  Contain.  1  grain  com- 
pound extract  colocynth,  J/2  grain  extract  hyoscyamus,  J/4  grain 
extract  leptandra,  J/3  grain  resin  jalap,  J/4  grain  resin  podo- 
phyllum.  Average  Dose:  2  pills. 

PILLS,    CHALYBEATE.      See    Pills    Iron    Carbonate. 
PILLS,  CHAPMAN'S.    See  Pills,  Dinner. 
PILLS  COCHIA.     See  Pills  Colocynth  Compound. 
PILLS,  COLE'S.    See  Pills,  Dinner. 


The  prices  of  the  Squibb  Products  are  in  all  instances  as  low  as 
the  quality  and  quantity  of  ingredients  and  the  expense  of  man- 
ufacture allow.  They  include  containers,  packing  and  boxing.  When 
ordering  or  prescribing  medicinal  products,  specify  SQUIBB'S. 


196        SQUIBB'S  MATERIA  MEDICA 
PILLS  COLOCYNTH  COMPOUND. 

Pilulte  Colocynthidii  Composite,  N.  F.;  Cochia  Pills.  Con- 
tain '  r,  grain  extract  colocynth,  2  grains  each  aloes  and  resin 
scammony,  ]/£  minim  oil  cloves.  Hydragogue  Cathartic.  Aver- 
age Dose:  I  pill. 

PILLS  COLOCYNTH  AND  HYOSCYAMUS. 

Pilulat  Colocynlhidis  el  Hyoscyami,  N.  F.  Contain  VlO  grain 
extract  colocynth,  lj/2  grains  each  aloes,  resin  scammony  and 
extract  hyoscyamus,  J/£  minim  oil  cloves.  Cathartic.  Average 
Dose:  1  pill. 

PILLS  COLOCYNTH  AND  PODOPHYLLUM. 

Pilulat  C  olocynthidis  et  Podophylli,  N.  F.  Contain  2J/2  grains 
compound  extract  colocynth  and  '74  grain  resin  podophyllum. 
Hydragogue  Cathartic.  Average  Dose:  1  pill. 

PILLS  DIGITALIS,  SQUILL  AND  MERCURY. 

Pilule  Digitalis,  Scillae  et  Hydrargyri,  N.  F.;  Niemeyer's 
Diuretic  Pills;  Guy's  Pills.  1  grain  each  digitalis,  squill, 
mercury  mass.  Average  Dose:  1  pill. 

PILLS,  DINNER. 

Pilulat   ad   Prandium,   N.   F.     Stomachic,    Laxative.      Average 

Dose:  1  pill.    The  National  Formularly  describes  the  following: 

Chapman's:    1J/2  grains  each  aloes  and  mastic,   1    grain  ipecac, 

1/4  grain  oil  fennel. 

Cole's :    1  '/5    grains   each   aloes,   mercury  mass   and  jalap,   1/50 

grain  tartar  emetic. 

HalPs:   1    grain  each  aloes,  extract  glycyrrhiza  and  soap. 

Lady   Webster's:  See  Pills  Aloes  and  Mastic. 

PILLS,  FERRUGINOUS.     See  Pills  Iron  Carbonate. 

PILLS,  FRANCIS'S  TRIPLEX.    See  Pills  Aloes,  Mercury  and  Scam- 
mony Compound. 

PILLS  GLONOIN.     See  Pills  Nitroglycerin. 

PILLS,  GRIFFITH'S.     See  Pills  Iron  Carbonate. 

PILLS,   GUY'S.     See   Pills   Digitalis,   Squill   and   Mercury. 

PILLS,  HALL'S     See  under  Pills,  Dinner. 

0  PILLS  IRON  CARBONATE. 

Pilules  Ferri  Carbonatis;  Blaud's  Pills;  Griffith's  Pills;  Iron 
Pills;  Ferruginous  or  Chalybeate  Pills.  1  grain  ferrous  car- 
bonate. Hematinic.  Average  Dose:  2  pills. 

PILLS  IRON   IODIDE. 

Pilules  Ferri  lodidi;  Blancard's  Pills.  1  grain  ferrous  iodide, 
with  powdered  extract  licorice,  sugar  and  acacia,  coated  with 
solution  balsam  tolu.  Alterative,  Hematinic.  Average  Dose : 
2  pills. 


SQUIBB'S  MATERIA  MEDICA        197 

PILLS  IRON,  QUININE,  ALOES  AND  Nux  VOMICA. 

Pilulce  fern,  Quinince,  Aloes  et  Nucis  Vomica,  N.  F.; 
Quadruplex  Pills,  N.  F.  Ill;  Pills  Iron  and  Quinine  Com- 
pound. I  grain  each  dried  ferrous  sulphate,  quinine  sulphate 
and  aloes,  J/4  grain  extract  nux  vomica.  Used  as  Tonic. 
Average  Dose:  I  pill. 

PILLS  IRON,  QUININE,  STRYCHNINE  AND  ARSENIC. 

Two  strengths  are  recognized  by  National  Formulary.  (1) 
Stronger^  (Metallic  Pills;  Bitter  Metallic  Pills):  1  grain  each 
reduced  iron  and  quinine  sulphate,  l/jjo  grain  each  strychnine 
and  arsenous  acid.  (2)  Mild  (Aiken's  Tonic  Pills)  :  %  grain 
reduced  iron,  1  grain  quinine  sulphate,  i/SO  grain  each  strych- 
nine and  arsenous  acid.  Tonic.  Average  Dose:  1  pill. 

PILLS,  JANEWAY'S.     See  Pills  Aloes  and  Podophyllum  Compound. 
PILLS,  LADY  WEBSTER'S.    See  Pills  Aloes  and  Mastic. 

PILLS  LAXATIVE  COMPOUND. 

Pilula  Laxativae  Composite,  N.  F.  About  '/£  grain  aloin, 
•'•/ISO  grain  strychnine,  J/g  grain  extract  belladonna  leaves, 
Vie  grain  ipecac.  Laxative.  Average  Dose:  2  pills 

PILLS  LAXATIVE  POST-PARTUM. 

Pilules  Laxalivcs  Posl-Parlum,  N.  F.;  Barker's  Post-Partum 
Pills.  ]2/}  grains  compound  extract  colocynth,  Yd  grain  aloes, 
5/i2  grain  extract  nux  vomica,  */12  grain  each  resin  podophyllum 
and  ipecac,  P/4  grains  extract  hyoscyamus.  Cathartic  for  lying- 
in  women.  Average  Dose:  1  pill. 

PILLS    METALLIC.      See     Pills    Iron,     Quinine,    Strychnine    and 
Arsenic,    Stronger. 

PILLS,    NIEMEYER'S   DIURETIC.     See   Pills   Digitalis,   Squill    and 
Mercury. 

PILLS,   NIEMEYER'S   PHTHISIS.     See   Pills   Opium,   Digitalis   and 
Quinine. 

PlLLS   NlTROGLYCERIN. 

Pilulce  C/pcerp/is  Niiralis,  N.  F.;  Pills  Glonoin.  Vioo  grain 
nitroglycerin.  Antispasmodic,  Vaso-dilator.  Average  Dose : 
1  pill. 

fPiLLs  OPIUM  AND  CAMPHOR. 

Pilulce  Opii  el  Camphors,  N.  F.  1  grain  powdered  opium,  2 
grains  camphor.  Intestinal  Astringent  and  Anodyne,  Antispas- 
modic. Average  Dose:  1  pill. 


If  difficulty  is  experienced  in  procuring  any  Squibb  product, 
in  the  original  packages  here  listed,  please  notify  us;  we 
shall  see  that  your  wants  are  met  promptly  and  satisfactorily. 


198       SQUIBB'S  MATERIA  MEDICA 

fPiLLs  OPIUM,  DIGITALIS  AND  QUININE. 

Pilules  Opii,  Digitalis  el  Quinince,  N.  F.;  Niemeyer's  Phthisis 
Pills.  About  ]/(,  grain  powdered  opium,  1  grain  digitalis,  1 
grain  quinine  sulphate.  Average  Dose:  1  pill. 

fPiLts  OPIUM  AND  LEAD. 

Pilules  Opii  el  Plumbi,  N.  F.  1  grain  each  powdered  opium 
and  lead  acetate.  Antidiarrheal.  Average  Dose:  1  pill. 

PILLS  PHOSPHORUS. 

Pilules  Phosphori.  1/ioo  grain  phosphorus.  Nerve  Stimulant, 
Reconstructive.  Average  Dose:  1  pill.  Antidotes:  potassium 
permanganate  solution,  emetics;  charcoal. 

PILLS,  PLUMMER'S.    See  Pills  Antimony  Compound. 

PILLS  POST-PARTUM,  BARKER'S.-   See  Pills  Laxative,  Post-Partum. 

PlLLS  QuADRUPLEX.        See   Pills   Iron,    Quinine,   Aloes   and   Nux 
Vomica. 

PILLS  RHUBARB. 

Pilules  Rhei,  N.  F.  About  3  grains  rhubarb,  I  grain  soap. 
Bitter  Tonic,  Stomachic.  Average  Dose:  1  pill. 

PILLS  RHUBARB  COMPOUND. 

Pilules  Rhei  Composites.  2  grains  rhubarb,  l'/2  grains  aloes, 
1  grain  myrrh,  with  oil  peppermint  as  corrective.  Laxative. 
Average  Dose:  2  pills. 

PlLLS,  RUFUS'S.     See  Pills  Aloes  and  Myrrh. 

PILLS  SCAMMONY  COMPOUND. 

See  Pills  Aloes,  Mercury  and  Scammony  Compound. 

PILLS  TRIPLEX.     See  Pills,  Aloes,  Mercury  and  Podophyllum. 
PILLS  VEGETABLE   COMPOUND.     See   Pills,  Cathartic,  Vegetable. 
PILLS,  WARBURG'S.    See  Pills  Antiperiodic. 

©  Pilocarpine  Hydrochloride,  Squibb 

15-grain  vial,  ;  10-grain  vial,  ;  5-grain  vial, 
Pilocarpines  HydroMoriJum.  CnHieOoNo.HCl.  Colorless, 
odorless,  faintly  bitter,  hygroscopic  crystals.  1  Gm.  dissolves 
in  0.3  mil  (Cc.)  water,  3  mils  alcohol,  366  chloroform;  in- 
soluble in  ether.  Incompatible  with  iodides,  calomel,  alkalies. 
Sialagogue,  Galactagogue,  Diaphoretic;  Myotic  externally. 
Average  Dose:  V»>  grain  (0.01  Gm.) ;  hypodermic,  VlU  grain 
(0.005  Gm.).  Antidotes:  tannin,  emetics;  atropine;  ammonia; 
brandy  later.  Keep  well  stoppered. 

©  PILOCARPINE  NITRATE. 

Pilocarpines  Nilras.  C] iHnjO^No.HNOs.  Colorless,  odor- 
less, faintly  bitter  crystals.  1  Gm.  dissolves  in  4  mils  (Cc.) 
water,  75  alcohol;  insoluble  in  chloroform,  ether.  Dose:  as 
preceding. 


SQUIBB'S  MATERIA  MEDICA        199 

PlLOCARPUS. 

Pilocarpus;  Jaborandi.  Dried  leaflets  of  Pilocarpus  Jaborandi 
or  P.  microphyllus  (Fam.  Rutacea).  Assays  not  less  than  0.6 
percent,  alkaloids.  Diuretic,  Diaphoretic,  Galactagogue.  (See 
also  Fluidextract.) 

Pimenta.       See  Allspice. 

PlMPINELLA. 

Pimpinella,  N.  F.  Dried  rhizome  and  roots  of  Pimpinella 
Saxifraga  or  of  P.  magna  (Fam.  Umbelliferai).  Aromatic 
odor;  sweetish,  pungent,  acrid  taste.  Formerly  used  as  Diur- 
etic Diaphoretic,  Stomachic.  Average  Dose:  15  grains  (1 
Cm.). 

PINEAL  GLAND   DRIED. 

Pineal  gland  of  young  cattle,  freed  from  connective  and  other 
tissue,  dried  and  powdered.  1  Gm.  represents  about  7  Gm. 
fresh  gland.  Used  in  backward  mental  development  of  chil- 
dren, mongolism,  etc.  Dose:  1/20  to  1/10  grain  (0.003  to 
0.006  Gm.)  three  times  daily. 

PlNKROOT.     See  Spigelia. 

PIPSISSEWA.     See  Chimaphila. 

PITUITARY  BODY  DESICCATED.    See  Hypophysis  Desiccated. 

PLASTER,  ADHESIVE.    See  Plaster  Rosin. 

©  PLASTER  BELLADONNA. 

Emplaslrum  Belladonna.  Adhesive  plaster  carrying  30  per- 
cent, extract  belladonna  leaves.  Assays  0.35  to  0.4  percent, 
alkaloids.  Anodyne. 

PLASTER,  BROWN,  CAMPHORATED. 

Emplaslrum  Fuscum  Camphoratum,  N.  F.;  Camphorated  Mother 
Plaster.  Red  oxide  lead,  olive  oil,  wax  and  camphor.  Anti- 
phlogistic, Discutient. 

PLASTER,  BLISTERING.    See  Plaster  Cantharides. 

PLASTER  CANTHARIDES. 

Emplaslrum  Cantharides;  Blistering  Plaster.  Cerate  cantharides 
spread  upon  rosin  plaster.  Epispastic. 

PLASTER  CAPSICUM. 

Emplaslrum  Capsici.  Oleoresin  capsicum  spread  over  rubber 
plaster.  Rubefacient,  Counter-irritant. 


The  Squibb  products  are  recognized  everywhere  as  the  Quality 
Standard.  They  are  of  uniform  purity  and  strength,  hence 
therapeutically  dependable.  When  ordering  or  prescribing  med- 
icinal products,  you  will  do  well  always  to  specify  SQUIBB'S. 


200       SQUIBB'S  MATERIA  MEDICA 

PLASTER  DIACHYLON.    See  Plaster  Lead. 

PLASTER,  ELASTIC. 

Emplaslrum  Elastlcum;  Rubber  Plaster;  Rubber  Adhesive 
Plaster.  Mixture  of  rubber,  resins  and  waxes,  with  a  filler  of 
absorbent  powder  such  as  orris  root  or  starch,  mechanically 
mixed  and  spread  upon  cotton  cloth  or  other  fabric. 

PLASTER  LEAD. 

Emplaslrum  Plumbi;  Diachylon  Plaster.  Now  made  from  lead 
oxide,  olive  oil  and  lard,  instead  of  lead  acetate  and  soap,  as 
previously  officially  directed.  Antiphlogistic. 

PLASTER,    MOTHER,    CAMPHORATED.      See    Plaster    Brown    Cam- 
phorated. 

®  PLASTER  MUSTARD. 

Emplaslrum  Sinapis;  Mustard  Paper.  Mixture  of  powdered 
black  mustard  and  rubber  solution,  spread  on  paper,  cotton 
cloth <pr  other  fabric.  Rubefacient,  Counterirritant. 

PLASTER  ROSIN. 

Emplastrum  Resinas;  Adhesive  Plaster;  Rosin  Adhesive  Plas- 
ter. Mixture  of  rosin  (14),  lead  plaster  (80),  and  yellow 
wax  (6). 

PLASTER  RUBBER  ADHESIVE.     See  Plaster  Elastic. 

PLASTER    SOAP. 

Emplaslrum  Saponis,  N.  F.  10  percent,  soap,  90  percent,  lead 
plaster.  Antiphlogistic,  Discutient. 

PLEURISY  ROOT.     See  Asclepias. 

PLUMMER'S  PILLS.     See  Pills  Antimony  Compound. 

Podophyllin.        See  Resin  Podophyllum. 

PODOPHYLLUM. 

Podophyllum;  Mandrake;  May  Apple  Rhizome.  Dried 
rhizome  and  roots  of  Podophyllum  peltatum  (Fam.  Ber- 
ieriJaceoe),  yielding  not  less  thari  3  percent,  resin.  Slight  odor; 
sweetish-bitter,  acrid  taste.  Slow  but  effective  and  rather 
irritant  Cathartic.  (See  also  Fluidextract;  Resin.) 

Poison  Nut.        See   Nux  Vomica. 
POKE  ROOT.     See  Phytolacca. 

POMEGRANATE. 

Cranalum.  Dried  bark  of  stems  and  roots  of  Punica  Crana- 
lum  (Fam.  Punicacece).  Anthelmintic.  Average  Dose:  30 
grains  (2  Gm.).  . 


SQUIBB'S  MATERIA  MEDICA        201 

POPPY  CAPSULES. 

Papaveris  Fructus,  N.  F.  Dried,  fully  grown,  unripe  fruit  of 
Papaver  Somniferum  (Fam.  Papaveracece) .  Weak  opiate. 
Average  Dose:  60  grains  (4  Cm.). 

Potassa.         See   Potassium   Hydroxide. 

Potassa  Sulphurated,  Squibb  bottle,  Ib.        ;  J4  lb. 

Potassa  Sulphurata;  Pure  Liver  of  Sulphur;  so-called  Potas- 
sium Sulphide.  Hard,  brown,  brittle  masses;  odoY  of  hydrogen 
sulphide;  bitter,  acrid,  alkaline  taste.  Soluble  in  water  (in- 
completely). Alterative,  Antiparasitic  Dermic.  Dose:  2  to  10 
grains  (0.13  to  0.65  Gm.).  On  exposure  it  absorbs  moisture, 
carbon  dioxide  and  oxygen,  and  becomes  changed. 

POTASSA  WITH  LIME. 

Potassa  cum  Calce,  N.  F.;  Vienna  Caustic  or  Lime.  Equal 
parts  potassium  hydroxide  and  calcium  oxide  (quicklime).  Caus- 
tic. Keep  well -stoppered,  in  dry  place. 

©  Potassium  Acetate,  Squibb  bottle,  Ib.  ;  '/4  lb. 
Potassii  Acelas.  KC^HsC^.  To  prevent  contamination  by 
metallic  impurities,  the  entire  process  of  manufacture,  including 
the  evaporation,  is  conducted  in  stoneware  vessels.  Best  medi- 
cinal quality,  free  from  discoloration.  White,  odorless,  very 
deliquescent  powder;  warming,  saline  taste.  1  Gm.  dissolves 
in  0.5  mil  (Cc.)  water,  2.9  mils  alcohol.  Systemic  Alkali, 
Diuretic;  in  dropsy,  gout,  rheumatism,  eczema,  etc.  Aver- 
age Dose:  15  grains  (1  Gm.),  in  sweetened  solution.  (See 
also  Reagents  [Part  IV].) 

Potassium  Benzoate,  Squibb  bottle,  oz. 

KC7H5O2.3H2O.  White,  crystalline  powder.  Soluble  in 
water  and  alcohol.  Mild  Antiseptic.  Dose:  10  to  20  grains 
(0.65  to  1.3  Gm.). 

©  Potassium  Bicarbonate,  Squibb 

carton,  lb.          ;  J/£  H>. 

Potassii  Bicarbonas.  KHCOg.  A  recrystallized,  especially 
pure  quality,  for  medicinal  and  pharmaceutical  uses.  White, 
odorless,  granular  salt;  saline,  slightly  alkaline  taste.  1  Gm.  dis- 
solves in  2.8  mils  (Cc.)  water;  almost  insoluble  in  alcohol.  Boiling 
changes  it  to  carbonate.  Mild  Alkali  employed  in  dys- 
pepsia, dropsy,  jaundice,  etc.  Average  Dose:  15  grains  (1 
Gm.).  (See  also  Tablets  [Part  II];  Reagents  [Part  IV].) 


Since  we  make  only  one  quality  of  each  product,  that  best 
suited  to  the  purposes  intended,  the  specification  "Squibb's" 
is  not  open  to  various  interpretations,  but  has  a  plain,  positive 
meaning.  When  ordering  or  prescribing,  specify  SQUIBB'S. 


202  .      SQUIBB'S  MATERIA  MEDICA 

Potassium  Bichromate.        See  Potassium  Dichromate. 

Potassium  Binoxalate,  Squibb         bottle,  Ib.         ;  !4  Ib. 
Sal  Acetosella;  Salt  of  Sorrel.     KHC2O4.HoO.     White  crys- 
tals.    Soluble    in    water.     Used    for    technical    purposes.     Anm 
tidotes:  lime  water,  magnesia;   emetics. 

Potassium  Bisulphate  Reagent.     See    Reagents    (Part    IV). 

®  Potassium  Bitartrate,  Squibb 

(Powdered)  tin,  Ib.        ;  |4  Ib. 

Potassii  Bilarlras;  Cream  of  Tartar;  Depurated  Tartar. 
KHC4H4O(j.  This  salt  is  frequently  found  largely  adul- 
terated. The  article  here  offered  complies  with  the  most  rigid 
medicinal  and  pharmaceutical  requirements.  White,  odorless 
powder;  pleasant,  acidulous  taste.  1  Gm.  dissolves  in  155 
mils  (Cc.)  water,  8820  alcohol.  Boric  acid  or  borax  increases 
aqueous  solubility.  Diuretic,  Aperient,  Refrigerant.  Average 
Dose:  diuretic,  30  grains  (2  Gm.)  ;  aperient,  120  to  240  grains 
(8  to  16  Gm.).  (See  also  Reagent  [Part  IV].) 

Potassium  Bromate  Reagent.  See  Reagents  (Part  IV). 

0  Potassium  Bromide,  Squibb  bottle,  Ib.  ;  '/4  Ib. 
Polassii  Bromidum.  KBr.  White,  odorless,  granular  powder; 
very  salty  taste.  1  Gm.  dissolves  in  1 .5  mils  (Cc.)  water,  about 
250  alcohol,  4.6  glycerin.  Incompatible  with  mineral  acids; 
with  salts  of  lead,  mercury  and  silver;  etc.  Nerve  Seda- 
tive, Antispasmodic ;  also  Reagent.  Average  Dose:  15  grains 
(I  Gm.).  Absorbed  and  eliminated  slowly,  and  when  long 
continued  should  be  omitted  for  a  few  days  in  every  month. 

POTASSIUM  BROMIDE,  GRANULAR  EFFERVESCENT. 

Sal  Polassii  BromiJi  Effervescent,  N.  F.  About  16.6  percent, 
potassium  bromide.  Average  Dose:  90  grains  (6  Gm.). 

POTASSIUM  BROMIDE,  GRANULAR  EFFERVESCENT  COMPOUND. 
Sal  Polassii  BromiJi  Effervescent  Composilus,  N.  F.;  formerly 
official  as  Potassium  Bromide  Effervescent  Granular,  with  Caf- 
feine. 8.3  percent,  potassium  bromide,  0.8  percent,  caffeine, 
4.2  percent.  lithium  carbonate.  Average  Dose:  90  grains  (6 
Gm.) 

0  Potassium  Carbonate,  Squibb 

(Powdered)  bottle,  Ib.         ;  |4  Ib. 

Polassii  Carbonas;  Sal  Tartar.  r^CO^.  White,  odorless, 
granular,  very  deliquescent  powder;  strongly  alkaline  taste. 
1  Gm.  dissolves  in  0.9  mil  (Cc.)  water;  insoluble  in  alcohol. 
Caustic,  Antipruritic,  Antacid.  Used  in  acid  dyspepsia, 
lithiasis,  jaundice,  etc.  Average  Dose:  15  grains  (I  Gm.). 
(See  also  Reagents  [Part  IV].) 


SQUIBB'S  MATERIA  MEDICA        203 

0  Potassium  Chlorate,  Squibb 

(Granular)  tin,  lb.         ;    \/4  lb. 

Potassii  Chloras.  KClOs.  A  special  Squibb  product,  repre- 
senting the  U.  S.  P.  market  grade  recrystallized  and  further 
purified;  hence  a  distinctive  product.  White,  odorless,  gran- 
ules; saline  taste.  1  Gm.  dissolves  in  11.5  mils  (Cc.)  water; 
soluble  in  glycerin;  almost  insoluble  in  alcohol.  Alterative, 
Antisialagogue,  Antiseptic,  Astringent.  Average  Dose :  4  grains 
(0.25  Gm.).  Applied  externally  in  3  to  5  percent,  solution,  cr 
ointment  or  dusting  powder;  as  mouthwash  and  gargle,  on 
ulcers,  etc.  Large  doses  are  poisonous,  causing  disintegration 
of  blood  corpuscles.  Incompatible  with  potassium  iodide 
and  tartaric  acid.  Dangerous  explosions  may  occur  when  it  is 
heated  or  subjected  to  concussion  or  trituralion  with  organic 
substances  (cork,  tannin,  sugar,  etc.)  or  with  sulphur,  antimony 
sulphide,  phosphorus  or  easily  oxidizable  substances.  Antidotes: 
emetics;  diuretics;  ice;  opium;  pilocarpine;  caffeine  subcu- 
taneously.  (See  also  Tablets  and  Troches  [Part  II];  Re- 
agents [Part  IV].) 

Potassium  Chloride,  Squibb  bottle,  %  lb. 

Polassii  Chloridum,  N.  F.  KCI.  White,  odorless  crystals  or 
granules.  I  Gm.  dissolves  in  2.8  mils  (Cc.)  water;  insoluble 
in  alcohol.  Uses  technical.  (See  also  Reagents  [Part  IV].) 

Potassium  Chromate,  Squibb  bottle,  %  lb. 

K2CrC>4.  Yellow  crystals.  Soluble  in  water.  Indicator  in 
volumetric  analysis.  Antidotes:  magnesia;  emetics;  alkaline 
carbonates.  (See  also  Reagents  [Part  IV].) 

©  Potassium  Citrate,  Squibb  bottle,  lb.  ;  %  Ib. 
Potassii  Citras.  KsCeHsOy.r-^O.  White,  odorless,  granular 
powder;  cooling,  saline  taste.  1  Gm.  dissolves  in  0.6  mil  (Cc.) 
water,  2  glycerin;  sparingly  soluble  in  alcohol.  Systemic  Al- 
kali, Diuretic,  Diaphoretic;  in  fevers,  bronchial  affections,  rheu- 
matism, etc.  Average  Dose:  15  grains  (1  Gm.). 

©  POTASSIUM  CITRATE,  GRANULAR  EFFERVESCENT. 

Polassii  Citras  Effervescens.  20  percent,  potassium  citrate. 
Average  Dose:  1  drachm  (4  Gm.). 

Potassium  Dichromate  Reagent.  See  Reagents  (Part  IV). 
Potassium  Ferricyanide  Reagent.  See  Reagents  (Part  IV). 
Potassium  Ferrocyanide  Reagent.  See  Reagents  (Part  IV). 


The  founder  of  the  House  of  Squibb,  Dr.  Edward  R.  Squibb, 
not  only  had  high  ideals,  but  lived  and  labored  for  them;  and, 
in  the  words  of  William  Miller  Bartlett,  "the  House  of  Squibb 
stands  today  as  a  living  monument  to  the  honor,  integrity,  zeal 
and  devotion  of  its  founder." 


204       SQUIBB'S  MATERIA  MEDICA 

Potassium  Glycerophosphate,     75%,  Squibb 

bottle,  J4  Ib.         ;  oz. 

Concentrated  aqueous  solution  of  CsHyOgPC^OIQo-  Yellow- 
ish, syrupy  liquid.  Soluble  in  water  in  all  proportions.  Used 
as  Nerve  Tonic.  Dose:  4  to  10  grains  (0.25  to  0.65  Gm.). 
usually  in  combination  with  other  glycerophosphates. 

0  Potassium  Hydroxide,  Squibb 

bottle,  Ib.         ;   |4  Ib. 

Polassii  H\) droxidum ;  Potassium  Hydrate;  Potassa;  Caustic 
Potash.  Assays  not  less  than  85  percent.  KOH.  Small, 
crushed  lumps;  very  acrid,  caustic  taste.  1  Gm.  dissolves 
in  0.9  mil  (Cc.)  water,  3  mils  alcohol,  2.5  glycerin.  Caustic, 
Antacid.  Dose:  1/2  to  1  grain  (0.03  to  0.65  Gm.),  well  di- 
luted. Antidotes:  water,  then  vinegar  or  lemon  juice,  emetics; 
demulcents.  NOTE:  On  exposure  potassium  hydroxide  readily 
absorbs  carbon  dioxide  and  moisture,  and  deliquesces.  Hence 
keep  well -stoppered,  in  dry  place.  (See  also  Reagents,  Part 
IV;  Solution.) 

Potassium  Hypophosphite,  Squibb 

bottle,  Ib.          ;  J4  Ib. 

Potassii  Hypophosphls.  KPHoC>2.  White,  opaque,  odorless, 
deliquescent  plates  or  masses,  or  granular  powder;  pungent, 
saline  taste.  I  Gm.  dissolves  in  0.6  mil  (Cc.)  water,  9  mils 
alcohol;  insoluble  in  ether.  Used  as  Nerve  Tonic.  Average 
Dose :  8  grains  (0.5  Gm.) .  Avoid  triturating  or  heat- 
ing with  oxidizing  agents,  such  as  nitrates  and  chlorates,  as 
explosion  is  liable  to  occur. 

0  Potassium  Iodide,  Squibb  *  Granulated  or  Crystals 

bottle,  Ib.         ;    %  Ib.         ;   oz. 

Poiassii  lodidum.  KI.  Faint,  iodine-like  odor;  pungent,  saline, 
afterwards  bitter,  taste.  I  Gm.  dissolves  in  0.7  mil  (Cc.) 
water.  22  mils  alcohol,  2  glycerin.  Alterative,  Resolvent, 
Antiluetic,  Saline  Expectorant.  Average  Dose:  5  grains  (0.3 
Gm.).  Incompatible  with  alkaloidal  salts,  chloral  hydrate,  min- 
eral acids,  etc.  (See  also  Tablets  [Part  II]  ;  Reagents  [Part 
IV].) 

©  Potassium  Nitrate,  Squibb 

*  Granulated  or  Powdered  tin,  Ib. 

Polassii  Nitras;  Saltpetre;  Nitre.  KNO.3.  Colorless,  odorless 
granules;  or  white  powder;  cooling,  saline,  pungent  taste.  1  Gm. 
dissolves  in  2.8  mils  (Cc.)  water,  620  alcohol;  soluble  in 
glycerin.  Diaphoretic,  Diuretic;  in  fevers,  asthma,  dropsy, 
rheumatism,  etc.  Average  Dose:  8  grains  (0.5  Gm.).  Anti- 
dotes: stimulants;  ice  water;  opium.  (See  also  Reagents 
[Part  IV].) 


SQUIBB'S  MATERIA  MEDICA        205 

0  Potassium  Permanganate,  Squibb 

bottle,  Ib.         ;  |4  W>.          ;  oz. 

Potatsii  Permanganas;  Potassium  Hypermanganate.  KMnO4. 
An  exceptionally  pure  salt;  all  large  crystals,  unlike  regular 
so-called  "large-crystal"  grade.  Slender,  dark-purple,  odorless 
prisms;  sweet,  afterwards  disagreeable,  astringent  taste.  1  Gm. 
dissolves  in  13.5  mils  (Cc.)  water;  decomposed  by  other  sol- 
vents. Deodorant,  Disinfectant,  Emmenagogue.  Used  mainly 
externally,  in  gonorrhea,  leucorrhea,  ulcers,  tonsillitis,  etc.;  in- 
ternally in  amenorrhea,  zymotic  diseases,  morphine  poisoning, 
etc.  Average  Dose:  1  grain  (0.065  Gm.),  in  tablets,  or  in  pills 
made  with  kaolin  and  petrolatum  or  with  cacao  butter.  Its 
stains  can  be  removed  with  oxalic  or  hydrochloric  acid.  Either 
in  dry  condition  or  in  concentrated  solution  it  should  not  be 
brought  into  contact  with  organic  or  readily  oxidizable  sub- 
stances; organic  solvents  should  be  avoided.  (See  also  Tablets 
[Part  II];  Reagents  [Part  IV].) 

Potassium  Persulphate  Reagent.  See  Reagents  (Part  IV). 

Potassium  Phenolsulphonate,  Squibb  bottle,  oz. 

Potassium  Sulphocarbolate  Powdered.  An  exceptionally  pure 
article,  free  from  sulphates,  chlorides,  and  metallic  impurities. 
Freely  soluble  in  water.  Used  as  Intestinal  Antiseptic.  Dose : 
3  to  10  grains  (0.2  to  0.65  Gm.). 

Potassium  Sulphate,  Squibb 

*  Crystals  carton,  Ib. 

Powdered  carton,  Ib. 

Potassii  Sulphas,  N.  F.  KoSO4.  White,  odorless  crystals  or 
powder;  bitter,  saline  taste.  1  Gm.  dissolves  in  10  mils  (Cc.) 
water;  insoluble  in  alcohol.  Saline  Cathartic,  like  sodium  sul- 
phate. Average  Dose:  ace.  to  N.  F.,  15  grains  (1  Gm.) ;  as 
cathartic,  up  to  240  grains  (15  Gm.).  (See  also  Reagents 
[Part  IV].) 

Potassium  Sulphide,     so-called.     See  Potassa  Sulphurated. 

Potassium   Sulphocyanate   Reagent.     See   Reagents    (Part 
IV). 

Potassium  Sulphocarbolate.  See  Potassium  Phenolsulphona'.e. 

Potassium  Tartrate,  Squibb  bottle,  Ib.        ;  %  Ib. 

Soluble  Tartar.  2K2C4H.iO(;.H2O.  Colorless,  odorless  crys- 
tals. Soluble  freely  in  water;  almost  insoluble  in  alcohol. 
Refrigerant,  Diuretic,  Laxative.  Dose :  diuretic  and  refriger- 
ant, 15  to  30  grains  (1  to  2  Gm.)  ;  laxative,  60  to  180  grains 
(4  to  12  Gm.)- 


The  Squibb  Ideals  have  taken  concrete  form  in  the  Squibb 
Products;  these  are  universally  recognized  as  standards  of 
uniform  Purity  and  Efficacy,  that  is,  general  Excellence  and 
Reliability.  Specify  SQUIBB'S  when  prescribing  or  ordering. 


206       SQUIBB'S  MATERIA  MEDICA 

0  Potassium  and  Sodium    I  art  rate,  Squibb 

(Powdered)  tin,  Ib.         ;  '/2  lb.         ;  14  lb. 

Potassii  el  Sod'ri  Tarlras;  Rochelle  or  Seignette  Salt;  Tar- 
tarated  Soda.  KNaC4H4O6.4H2O.  A  recrystallized  grade, 
free  from  calcium  salts,  more  pleasant  to  the  taste  than  ordinary 
product.  I  Gm.  dissolves  in  0.9  mil  (Cc.)  water;  almost  in- 
soluble in  alcohol.  Saline  Cathartic.  Average  Dose:  150 
grains  (10  Gm.).  (See  also  Reagents  [Part  IV].) 

POULTICE,  EMOLLIENT. 

Species  Emollientes,  N.  F.  Equal  parts  althaea  leaves,  mallow 
leaves,  m«lilot,  matricaria  and  linseed,  powdered.  Mixed  with 
hot  water  for  use. 

POULTICE   SPICE.      See    Powder,    Rubefacient   Spice. 

Powder  Acetanilid  Compound,  Squibb 

tin,  lb.         ;    %  lb. 

Pulvis  Acetanilidi  Compositus,  N.  F.  Acetanilid  70  percent., 
caffeine  10,  sodium  bicarbonate  20.  Analgesic,  Antipyretic. 
Average  Dose:  5  grains  (0.3  Gm.). 

POWDER  ALOES  AND  CANELLA. 

Pulvis  Aloes  el  Canella,  N.  F.;  Hiera  Picra.  Contains  aloes 
80  percent.,  canella  20.  Laxative.  Average  Dose:  5  grains 
(0.3  Gm.). 

Powder  Alum    Compound,  Squibb  per  doz.  tins, 

Surgical  Powder.  Introduced  by  Dr.  E.  R.  Squibb  in  1868, 
it  has  steadily  grown  in  favor  among  the  medical  profession  as 
an  emergency  dressing  and  wash.  Efficacious  and  safe  for 
external  use.  The  ingredients  are  burnt  alum,  camphor  and 
carbolic  acid.  Considered  especially  valuable  as  an  Astrin- 
gent, Absorbent  and  Antiseptic  dry  dressing  for  wounds.  The 
effect  is  sometimes  a  stinging  sensation,  but  regularly  followed 
by  a  rapid  and  continuous  healing.  It  should  be  used  freely, 
keeping  the  surfaces  well  covered  with  the  powder  as  long  as 
there  is  any  discharge.  Very  useful  also  as  a  Styptic  in  bleed- 
ing cuts  and  wounds  (dry  powder)  ;  and  as  an  Antiphlogistic  in 
inflamed  throat  and  other  catarrhs  of  the  mucous  passages 
(strong  warm  solution).  As  the  efficacy  of  this  powder  depends 
upon  its  perfect  freedom  from  moisture,  it  is  offered  only  in 
original,  special  tins,  which  should  be  kept  well  closed  and  in 
dry  place  when  not  in  use. 

POWDER,  ANTIMONIAL. 

Pulvis  Anlimonialis,  N.  F. ;  James'  Powder.  33  percent,  anti- 
mony oxide,  67  percent,  precipitated  calcium  phosphate.  Dia- 
phoretic, Alterative.  Average  Dose:  3  grains  (0.2  Gm.). 


SQUIBB'S  MATERIA  MEDICA        207 

Powder,  Antiseptic  (Soluble),  Squibb 

bottle,  Ib.         ;  |4  Ib. 

Pulvis  Antisepticus,  N.  F.;  Soluble  Antiseptic  Powder. 
Powdered  salicylic  acid  0.5  percent.,  carbolic  acid  0.1, 
eucalyptol  0.!,  menthol  0.1,  thymol  0.1,  zinc  sulphate  12.5, 
boric  acid  86.6.  Antiseptic;  as  dusting  powder  or  in  solution 
(5  percent.). 

Powder,  Aromatic,  Squibb  tin,  Ib.        ;  |4  Ib. 

Pulvis  Aromaticus.  35  percent,  each  Saigon  cinnamon  and 
Jamaica  ginger,  15  percent,  each  cardamom  and  nutmeg.  Car- 
minative, Stomachic.  Average  Dose:  15  grains  (1  Cm.). 

POWDER  BAYBERRY  COMPOUND. 

Pulvis  A/pricce  Compositus,  N.  F.;  Composition  Powder. 
60  percent,  bayberry  root-bark,  30  percent,  ginger,  5  percent, 
each  capsicum  and  cloves.  Carminative.  Average  Dose:  15 

grains    (1    Gm.) 

POWDER  CALOMEL  AND  JALAP. 

Pulvis  Hydrargyri  Chloridi  Mills  et  Jalapa,  N.  F.  Calomel 
34  percent.,  jalap  66.  Drastic  Cathartic.  Average  Dose: 
10  grains  (0.65  Gm.). 

POWDER  CHALK  AROMATIC. 

Pulvis  Crelcs  Aromaticus,  N.  F.  Cinnamon  8  percent.,  nut- 
meg 6,  cloves  3,  cardamom  2,  prepared  chalk  25,  and  sugar  56. 
Antacid  Carminative,  Antidiarrheal.  Average  Dose:  30  grains 
(2  Gm.). 

f  POWDER  CHALK  AROMATIC,  WITH  OPIUM. 

Puhis  Crete  ^Aromaticus  cum  Opio,  N.  F.  Powdered 
opium  2.5  percent.,  aromatic  chalk  powder  97.5.  Anti- 
diarrheal. Average  Dose:  15  grains  (1  Gm.). 

Powder  Chalk    Compound,  Squibb 

tin,  Ib.          ;    14  Ib. 

Pulvis  Crete  Composi/us.  Prepared  chalk  30  percent.,  acacia 
20,  sugar  50.  Antacid,  in  diarrhea.  Average  Dose:  30  grains 
(2  Gm.). 

POWDER,  COMPOSITION.     See  Powder  Bayberry  Compound. 
Powder,   Dover's.        See  Powder   Ipecac  and  Opium. 
Powder,    Dover's,    Liquid.       See  Tincture  Ipecac  and  Opium. 
Powder,  Effervescing  Compound.     See  Powder  Seidlitz. 


The  Squibb  Label  on  a  package  is  a  positive  guaranty  for  the 
uniform  Purity  and  Reliability  of  the  product.  We  make  only 
ONE  quality:  the  SQUIBB  quality;  and  our  prices  are  as  low 
as  they  can  be  made  for  that  quality.  Specify  SQUIBB'S. 


208       SQUIBB'S  MATERIA  MEDICA 

POWDER,  FOOT.       See  Powder  Talcum  Compound. 

POWDER  GAMBIR  COMPOUND. 

Puhis  Cambir  Composilus,  N.  F.  Gambir  40  percent.,  kino 
20,  kramena  20,  cinnamon  10,  nutmeg  10.  Antidiarrheal. 
Average  Dose:  20  grains  (1.3  Gm.). 

Powder  Qlycyrrhiza  Compound,  Squibb. 

tin,  Ib.         ;    14   Ib. 

Puhis  Glycyrrhizat  Composilus,  U.  S.  P.  1880;  Compound 
Licorice  Powder.  Consists  of  licorice  root  16  percent., 
senna  18,  washed  sulphur  8,  ground  fennel  8  and  sugar  50. 
Considered  therapeutically  superior  to  present  U.  S.  P.  article, 
and  also  more  stable  and  uniform.  Laxative.  Average  Dose  : 
60  grains  (4  Gm.). 

Powder,  Gray.       See  Mercury  with  Chalk. 
POWDER,  GREGORY'S.     See  Powder,  Rhubarb  Compound. 

f  Powder  Ipecac  and  Opium,  Squibb 

tin,  Ib.         ;  |4  N>.          '•  °z- 

Puhis  Ipecacuanha  el  Opil;  Dover's  Powder;  Compound 
Ipecac  Powder.  Contains  ipecac  and  powdered  opium  (each 
10  percent.),  but  the  potassium  sulphate  (in  U.  S.  P.  1870 
formula)  is  retained  in  place  of  the  milk  sugar  now  prescribed. 
Considered  a  superior  preparation.  Squibb's  Dover's  Powder 
has  long  been  the  standard,  and  is  a  product  made  by  the 
exercise  of  greatest  thoroughness  and  manipulative  skill.  Ano- 
dyne, Antispasmodic,  Diaphoretic.  Average  Dose:  8  grains 
(0.5  Gm.).  Antidotes:  potassium  permanganate  solution, 
emetic  hypodermically;  atropine  or  strychnine;  hot,  strong 
coffee;  exercise. 

Powder  Ipecac  Compound.     See  Powder  Ipecac  and  Opium. 

Powder  Jalap  Compound,  Squibb    tin,  Ib.        ;   %  Ib. 
Puhis  Jalapa  Compositus.     Jalap  35  percent.,  potassium  bitar- 
trate  65.     Hydragogue  Cathartic;    in  dropsy  of  hepatic  causa- 
tion, obstinate  constipation,  etc.     Average  Dose:  30  grains   (2 
Gm.). 

f  POWDER  KINO  AND  OPIUM  COMPOUND. 

Puhis  Kino  el  Opii  Compositus,  N.  F.;  Powder  Kino  Com- 
pound, N.  F.  III.  Kino  75c/c,  powdered  opium  5f/c,  Saigon 
cinnamon  20%.  Intestinal  Astringent.  Average  Dose:  15 
grains  (1  Gm.). 

Powder  Licorice  Compound,  Squibb. 

See    Powder    Glycyrrhiza    Compound. 

Powder   Opium   and    Ipecac.      See  Powder  Ipecac  and  Opium. 


SQUIBB'S  MATERIA  MEDICA       209 

Powder  Pancreatin  Compound,  Squibb 

bottle,  J4  lb.          ;  oz. 

Pulvis  Pancreatinl  Composiius,  N.  F.;  Peptonizing  Powder. 
Pancreatin  20  percent.,  sodium  bicarbonate  80.  25  grains  suffi- 
cient to  peptonize  1  pint  fresh  cow's  milk. 

Powder,  Peptonizing.         See  Powder  Pancreatin  Compound. 

POWDER  RHUBARB  COMPOUND. 

Puhis  Rhei  Compositus;  Rhubarb  and  Magnesia;  Gregory's 
Powder.  Rhubarb  25  percent.,  Jamaica  ginger  10,  magnesium 
oxide  65.  Antacid,  Carminative,  Laxative;  chiefly  in  children. 
Average  Dose:  30  grains  (2  Gm.). 

POWDER  RHUBARB  AND  MAGNESIA,  ANISATED. 

Puhis  Rhei  el  Magnesia  Anisatus,  N.  F.;  Compound  Anise 
Powder.  Rhubarb  35  percent.,  heavy  magnesia  65,  with 
anethol  as  corrective.  Carminative,  Antacid,  Laxative;  largely 
in  infants.  Average  Dose  (infants):  5  grains  (0.3  dm.). 

POWDER,  RUBEFACIENT  SPICE. 

Puhis  Aromaticus  Rubefaciens,  N.  F.  Replacing  Aromatic 
Plaster,  N.  F.  III.  30%  clove,  30%  cinnamon,  20%  ginger, 
20%  capsicum.  Rubefacient  poultice  material. 

Powder,   Seidlitz,   Squibb  bottle,  lb.        ;  %  lb. 

This  effervescent  saline  mixture  is  Seidlitz  Powder  mixed 
together  into  a  single  powder,  the  constituents  being  all  sep- 
arately well  dried  before  being  mixed.  It  consists  of  potassium 
and  sodium  tartrate  (Rochelle  salt),  sodium  bicarbonate,  tar- 
taric  acid,  and  sodium  chloride,  the  latter  being  added  to  en- 
hance its  medicinal  activity  and  palatability.  As  an  Aperient 
the  dose  is  one  to  three  teaspoonfuls  (5  to  15  Gm.)  with  or 
without  sugar,  stirred  into  three-fourths  of  a  large  glassful  of 
cold  water,  and  drunk  at  once  while  the  powder  is  suspended 
in  the  water.  For  use  as  an  alkaline  mineral  water,  or  as  a 
substitute  for  Rochelle  salt,  about  ]/2  teaspoonful,  stirred  into 
the  same  quantity  of  water  as  above,  and  taken  two  or  three 
times  a  day,  may  be  sufficient.  In  the  use  of  this  powder  the 
effervescence  is  intentionally  slight,  or,  if  the  water  be  very  cold 
(as  it  should  be),  is  hardly  perceptible,  as  the  liberation  of  the 
carbonic  acid  is  intended  to  take  place  slowly  internally  where 
it  may  be  of  service.  Dampness  should  be  carefully  excluded. 

Powder,   Soluble  Antiseptic.         See   Powder,  Antiseptic. 
Powder,  Surgical.     See  Powder  Alum  Compound.  • 


This  house  supplies  only  one  quality  of  each  product:  that  best 
suited  to  the  purposes  intended.  The  specification  "Squibb's" 
is  not  open  to  various  interpretations;  it  has  a  plain,  posi- 
tive meaning.  When  prescribing,  please  specify  SQUIBB'S, 


210       SQUIBB'S  MATERIA  MEDICA 

Powder  Talcum.     See  Talcum  Powder. 

POWDER  TALCUM  COMPOUND. 

Pufais  Talci  Composites,  N.  F.;  Powder  Talc  Salicylated,  N. 
F.  III.  Salicylic  acid  3%,  boric  acid  10%,  talcum  87%. 
Antiseptic,  Deodorant,  Antihydrotic  dusting  powder. 

Powder,  Veterinary,  Squibb  tin,  perdoz. 

Used  by  the  veterinary  profession  for  many  years,  as  an  effica- 
cious, safe  Antiseptic,  Astringent  and  Absorbent  dressing  for 
wounds.  The  therapeutically  active  ingredients  are  burnt  alum, 
camphor,  carbolic  acid  and  charcoal.  It  should  be  used  in 
sufficient  quantity  to  keep  the  wound  surface  dry.  Serviceable 
also  as  a  Styptic  on  incised  and  other  bleeding  wounds,  applied 
freely  in  dry  powder.  Sold  only  in  original  tins,  which  should 
be  kept  well  closed  and  in  dry  place  when  not  in  use. 

Precipitate,  Red.        Sec  Mercury  Oxide  Red. 
Precipitate;  White.         See  Mercury  Ammoniated. 
Precipitate,   Yellow.        See  Mercury  Oxide  Yellow. 
PRICKLY  ASH   BARK.     See   Xanthoxylum. 

PRICKLY  ASH  BERRIES. 

Xanthoxyll  Fructus,  N.  F.  Dried  fruit  of  Xanthoxylum  ameri- 
canum  or  of  X.  Clava-Herculis  (Fam.  Rulaceee).  Faint  odor; 
warm,  aromatic  taste.  Used  as  Sialagogue,  Carminative,  Alter- 
ative. Average  Dose:  15  grains  (1  Gm.). 

PRINCE'S  PINE.    See  Chimaphila. 

®  PROCAINE. 

Name  adopted  by  Federal  Trade  Commission  for  novocain  as 
made  in  America.  Para-aminobenzo  methylaminoethanol 
Hydrochloride.  Colorless  needles.  Soluble  in  1  part  water, 
30  alcohol.  Local  Anesthetic,  like  cocaine;  solutions  are 
sterilizable. 

PROTAN. 

Compound  of  casein  and  tannic  acid  (50  percent.)-  Light- 
brown,  tasteless,  water-insoluble  powder.  Intestinal  Astringent. 
Dose:  15  to  30  grains  (1  to  2  Gm.). 

Protargentum,  Squibb  1  oz.  vial 

Compound  of  silver  and  protein,  containing  about  8  percent.  Ag. 
Chocolate-brown,  odorless  powder;  taste  bitter  and  metallic. 
Soluble  rather  slowly  but  freely  in  water;  insoluble  in  alcohol 
or  oils.  Solutions  not  precipitated  by  usual  silver  reagents,  nor 
affected  by  cocaine  hydrochloride  in  weak  solutions.  Used  in 
urethritis  and  inflammation  of  eyes  and  nose,  in  j/4  to  5  per- 
cent, solutions,  which  should  preferably  be  made  fresh  as 
wanted.  (See  also  Solargentum,  containing  20  percent.  Ag.) 


SQUIBB'S  MATERIA  MEDICA       211 

PROTARGOL. 

Silver-proteid.  Light-brown,  bulky  powder;  8.3  percent,  silver. 
Soluble  freely  in  water  or  glycerin;  not  precipitated  by  alkalies, 
albumen  or  chlorides.  Bactericide,  Antigonorrheit,  Antipyic. 
Incompatible  in  solution  with  lead  acetate,  zinc  sulphate,  copper 
sulphate,  alum,  or  mercuric  chloride.  Its  solutions  should  be 
made  with  cold  water.  Applied  externally  in  acute  cases  in 
!/4  to  1  percent,  solutions;  in  chronic  cases,  in  5  to  10  percent, 
strengths.  Dose :  1  to  3  grains  (0.065  to  0.2  Gm.).  (See  also 
Protargenrum.) 

PRUNE. 

Prttnum,  N.  F.  Partly  dried,  ripe  fruit  of  Prunus  Jomeslica 
(Fam.  Rosacece).  Laxative  Nutritive. 

Prussian  Blue,  Insoluble.        See  Iron  Ferrocyanide. 

PULSATILLA. 

Puhatilla,  N.  F.  Dried  herb  of  Anemone  Pulsalllla,  A. 
pratensis  or  of  A.  Ludoviciana  (Fam.  Ranunculacece) .  Nearly 
odorless;  very  acrid  taste.  Used  as  Alterative,  Sedative,  Anti- 
spasmodic.  Average  Dose:  5  grains  (0.3  Gm.). 

PUMICE. 

Pumex,  N.  F.  Combination  of  complex  silicates  of  aluminum, 
potassium  and  sodium,  of  volcanic  origin.  Abrasive,  Polishing 
material;  also  used  chemically. 

PUMPKIN  SEED. 

Pepo.  Dried  ripe  seeds  of  cultivated  varieties  of  Cucurbila 
Pepo  (Fam.  Cucurbitacece).  Domestic  Anthelmintic.  Aver- 
age Dose:  1  ounce  (30  Gm.). 

PUNICINE  TANNATE.      See  Pelletierine  Tannate. 

PYRAMIDON. 

Dimethylaminoantipyrine.  Small,  white,  nearly  tasteless  crys- 
tals. Soluble  in  about  1 1  parts  water;  readily  in  alcohol  or  ether. 
Incompatible  with  ferric  chloride  and  spirit  nitrous  ether.  Anti- 
pyretic, Analgesic.  Dose:  5  to  8  grains  (0.3  to  0.75  Gm.). 

PYRETHRUM. 

Pyrelhrum ;  Pellitory  Root.  Dried  root  of  Anacydus  Py- 
relhrum  (Fam.  Composite).  Sialagogue,  Stimulant  Mastica- 
tory, Local  Irritant.  Average  Dose:  30  grains  (2  Gm.). 


The  prices  of  the  Squibb  Products  are  in  all  instances  as  low  as 
the  quality  and  quantity  of  ingredients  and  the  expense  of  man- 
ufacture allow.  They  include  containers,  packing  and  boxing.  When 
ordering  or  prescribing  medicinal  products,  specify  SQUIBB'S. 


212        SQUIBB'S  MATERIA  MEDICA 

Pyrogallol,  Squibb 

(Acid  Pyrogallic)  tin,  Ib.          ;  |4  lb.         5  oz. 

Pyrogallol;  Trihydroxybenzene.  CgHsCOHs).  Light,  white, 
odorless,  bitter  laminae  or  needles.  I  Gm.  dissolves  in  1 .7 
mils  (Cc.). water,  1.3  mils  alcohol,  1.6  ether.  Incompatible  in 
trituration  with  antipyrine,  camphor,  carbolic  acid,  iodine,  lead 
acetate  or  menthol.  Antiparasitic  Dermic,  in  5  to  10  percent, 
ointment;  also  Reagent,  and  photographic  developer. 

PYROXYLIN. 

Pyroxylinum ;  Soluble  Gun  Cotton;  Collodion  Cotton;  Colloxy- 
lin.  Obtained  by  action  of  mixture  of  nitric  and  sulphuric 
acids  on  cotton.  Consists  chiefly  of  cellulose  tetranitrate.  Used 
for  making  collodion.  Very  inflammable! 

QUASSIA. 

Quassia;  Bitter  Wood.  Wood  of  Picrasma  excelsa  or  of 
Quassia  amara  (Fam.  SimaTubace.ee),  Jamaica  and  Surinam 
quassias.  Bitter  Tonic;  infusion  is  used  as  enema  as  Vermicide. 
Average  Dose:  8  grains  (0.5  Gm.). 

QUEBRACHO.     See  Aspidosperma. 
QUEEN'S  ROOT.     See  Stillingia. 

QUERCUS. 

Quercus,  N.  F.  Dried  bark  of  trunk  and  branches  of  Quercus 
alba  (Fam.  Fagacics),  deprived  of  periderm.  Distinct  odor; 
strongly  astringent  taste.  Tannin-bearing  Astringent.  Aver- 
age Dose:  15  grains  (1  Gm.). 

Quevenne's   Iron.        See  Iron  Reduced. 
Quicklime.        See  Lime. 
Quicksilver.         See  Mercury. 

QuiLLAJA. 

Qui//a/a,  N.  F.;  Soap  Bark.  Dried  bark  of  Quillaja  Saponan'a 
(Fam.  Rosacece),  deprived  of  periderm.  Slight  odor;  acrid 
taste.  The  powdered  root  is  strongly  sternutatory.  Expector- 
ant, Antiparasitic  Dermic. 

QuiNIDINE. 

Quinidina,  N.  F.  CooHo-iOoN?.  Alkaloid  of  cinchona, 
isomenc  with  quinine.  White,  odorless,  very  bitter  crystals  or 
powder.  1  Gm.  dissolves  in  about  32  mils  (Cc.)  alcohol,  53 
ether,  1.5  chloroform;  almost  insoluble  in  water.  Action,  Dose, 
etc.,  as  of  quinine  alkaloid.  At  one  time  recommended  as 
cheap  substitute  for  quinine;  inferior  to  it. 


SQUIBB'S  MATERIA  MEDICA       213 

0  Quinine  Alkaloid,  Squibb  bottle,  oz. 

Quinina.  C2oH24OoN2.3H2O.  White,  odorless,  bitter,  slight- 
ly efflorescent  powder.  1  Gm.  dissolves  in  1560  mils  (Cc.) 
water,  0.8  alcohol,  1.1  chloroform,  1.9  ether,  150  glycerin.  Anti- 
periodic,  Bitter  Tonic,  Ecbolic,  Antiseptic,  Antipyretic.  Aver- 
age Dose:  Tonic  lj/2  grains  (0.1  Gm.) ;  Antiperiodic,  at  least 
15  grains  (1  Gm.)  daily.  Contraindicated  in  ear  diseases. 
Used  externally  on  wounds. 

Quinine  Bisulphate,  Squibb  bottle,  oz. 

Quinines  Bisulphas;  Acid  Quinine  Sulphate.  C2oH24C>2N2.- 
H2SC>4.7H2O.  Colorless,  transparent  or  whitish  crystals  or 
small  needles;  odorless;  very  bitter.  Efflorescent,  and  turns 
yellow  on  exposure  to  light.  1  Gm.  dissolves  in  9  mils  (Cc.) 
water,  23  alcohol,  15  glycerin,  625  chloroform,  2500  ether. 
Action  and  dose:  as  of  quinine  alkaloid.  Used  largely  sub- 
cutaneously;  also  in  coryza  (0.2  percent,  solution).  (See 
also  Tablets  [Part  II].) 

Quinine  Dihydrochloride,  Squibb  bottle,  oz. 

Quinines  Dihydrochloridum.  C2oH24C>2N2.2HCl.  White, 
odorless,  very  bitter  powder.  1  Gm.  dissolves  in  0.6  mil  (Cc.) 
water,  12  alcohol;  slightly  soluble  in  chloroform  or  ether.  Dark- 
ened by  light.  Preferred  for  hypodermic  use;  used  also  in 
whooping-cough.  Dose:  as  of  quinine  alkaloid.  (See  also 
Ampuls.) 

QUININE  ETHYLCARBONATE.     See  Euquinine. 

Quinine  Glycerophosphate,  Squibb  bottle,  oz. 

Quinines  Glycerophosphas,  N.  F.  White,  odorless,  bitter  pow- 
der; 68  percent,  quinine.  1  Gm.  dissolves  in  about  850  mils 
(Cc.)  water,  75  alcohol ;  slightly  soluble  in  chloroform  or 
ether.  Used  as  Nerve  Tonic,  Antiperiodic;  chiefly  in  malaria 
with  nervous  debility.  Average  Dose:  tonic,  P/2  grains  (0.1 
Gm.)  ;  antiperiodic,  15  grains  (I  Gm.). 

Quinine  Hydrobromide,  Squibb  bottle,  oz. 

Quinines  Hydrobromidum;  Quinine  Bromide.  C2oH94O2N9.- 
HBr.H2O.  White,  light,  silky,  odorless;  very  bitter,  efflores- 
cent. 1  Gm.  dissolves  in  40  mils  (Cc.)  water,  0.9  alcohol,  7 
glycerin,  0.6  chloroform,  23  ether.  Action  and  dose:  as  of 
quinine  alkaloid. 

©  Quinine  Hydrochloride,  Squibb  bottle,  oz. 

Quinines  Hydrochloridum ;  Quinine  Hydrochlorate.  CooHo4- 
OL.No.HC1.2H2O.  White,  silky,  odorless,  very  bitter  needfes. 
I  Gm.  dissolves  in  18  mils  (Cc.)  water,  0.8  alcohol,  7  glycerin, 
0.7  chloroform,  340  ether.  Action  and  dose:  as  of  quinine 
alkaloid.  (See  also  Tablets  [Part  II].) 


If  difficulty  is  experienced  in  procuring  any  Squibb  product, 
in  the  original  packages  here  listed,  olease  notify  us;  we 
shall  see  that  your  wants  are  met  promptly  and  satisfactorily. 


214        SQUIBB'S  MATERIA  MEDICA 
Quinine  Hypophosphite,  Squibb  bottle,  oz. 

Quinin<e  Hypophosphis,  N.  F.  C2oH24O2N2.HsPO2.2H2O. 
Small,  white,  odorless,  bitter  crystals.  1  Cm.  dissolves  in  about 
35  mils  (Cc.)  water,  12.5  alcohol,  27  chloroform;  almost  in- 
soluble in  ether.  Action  and  dose:  like  quinine  alkaloid. 

Quinine  Oleate.  See  Oleate  Quinine. 

Quinine  Salicylate,  Squibb 

Quinine  Salic\)las.  C2oH24O2No.C7H6O3.HoO.  Colorless, 
odorless  needles,  becoming  pinkish  on  keeping.  1  Gm.  dissolves 
in  14  mils  (Cc.)  alcohol,  13  glycerin,  25  chloroform,  160  ether; 
slightly  soluble  in  water.  Bitter  Tonic,  Antineuralgic,  Anti- 
periodic;  in  rheumatism,  lumbago,  typhoid  fever,  etc.  Average 
Dose :  tonic,  1 J/2  grains  (0.1  Gm.) ;  antiperiodic,  at  least  1 5 
grains  (1  Gm.)  daily. 

0  Quinine  Sulphate,  Squibb 

tin,  5  ozs.,  per  oz.          ;  bottle,  oz. 

Quinine  Sulphas.  (C2oH24OoN2)oH2SO47H2O.  White 
silky,  flexible,  glistening,  odorless,  extremely  bitter  needles. 
1  Gm.  dissolves  in  725  mils  (Cc.)  water,  107  alcohol,  30  glycer- 
in; sparingly  soluble  in  chloroform  or  ether.  Dilute  acids 
increase  aqueous  solubility.  Action  and  dose:  as  of  quinine 
alkaloid.  Best  given  with  or  followed  by  an  acid.  (See  also 
Tablets  [Part  II].) 

0  Quinine  Tannate,  Squibb  bottle,  oz. 

Quinines  Tannas.  C2oH24O2N23Ci4HioO9.8HoO.  Yellow- 
ish-white, odorless,  nearly  tasteless  powder;  30  to  35  percent, 
anhydrous  quinine.  Slightly  soluble  in  water,  chloroform  or 
ether;  more  soluble  in  alcohol.  Used  mainly  in  children,  be- 
cause of  relative  tastelessness.  Average  Dose:  3  grains  (0.2 
Gm.),  in  milk. 

Quinine  Valerate,  Squibb  bottle,  oz. 

Quinine  Valeras,.  N.  F.  C2oH24O2N2.C5HioOo.H2O. 
White,  shining  crystals;  valerian  odor;  bitter  taste.  Sparingly 
soluble  in  water,  becoming  less  soluble  with  age;  readily  solu- 
ble in  alcohol.  Nervine,  Antiperiodic;  in  hemicrania,  hysteria 
and  other  neuroses  associated  with  malaria.  Average  Dose : 
nervine,  1J/2  grains  (0.1  Gm.) ;  antiperiodic,  at  least  15  grains 
(1  Gm.)  daily. 

Quinine  and  Iron  Citrate.        See  Iron  and  Quinine  Citrate. 

0  Quinine  and  Urea  Hydrochloride,  Squibb  bottle,  oz. 
10-grain  hermetically  sealed  tubes,  box  of  10, 

Quinines  et  Ureas  Hydrochloridum ;  Carbamidated  Quinine 
Dihydrochloride.  Co0Ho4OoNo.HCI.CO.(NH2)  j.HC1.5HoO. 
Colorless,  odorless,  bitter  crystals;  about  58  percent,  anhydrous 
quinine.  1  Gm.  dissolves  in  0.9  mil  (Cc.)  water,  2.4  mils 
alcohol.  Subcutaneous  Antiperiodic;  Local  Anesthetic  with 
hemostatic  action,  in  J/2  to  1  percent  solutions  by  injection 
and  10  to  20  percent,  solutions  topically.  Average  Dose:  15 
grains  (1  Gm.).  (See  also  Ampuls.) 


SQUIBB'S  MATERIA  MEDICA        215 

RASPBERRIES. 

Rubi  Ideei  Fructus,  N.  F.  Fresh,  ripe  fruit  of  varieties  of 
Rubus  Idteus  or  of  R.  strigosus  (Fam.  Rosaceai), 

Reagents,    Test    Solutions,    Volumetric   Solutions    and 
Indicators.       See  Part  IV. 

Red    Bark.        See  Cinchona,  Red. 

RED  CLOVER.     See  Trifolium. 

RED   SAUNDERS.     See   Sandal   Wood,   Red. 

Rennin,  Squibb  bottle,  oz. 

Renninum,  N.  F.  Milk-curdling  enzyme  from  stomach  of  calf; 
1  part  added  to  25,000  parts  fresh  cow's  milk  heated  to  105° 
F.  produces  a  fine  curd  in  ten  minutes.  Used  for  making 
liquid  rennet,  junket,  essence  pepsin,  and  similar  preparations. 

Resin  Guaiac.          See  Guaiac  Resin. 

Resin  Jalap,  Squibb  bottle,  oz. 

Resina  Jalapa.  Yellowish-gray  to  yellowish-brown  powder; 
slight,  peculiar  odor;  acrid  taste.  Soluble  in  alcohol  in  all 
proportions;  in  about  5  parts  ammonia  water.  Drastic  Hydra- 
gogue,  Cathartic.  Average  Dose:  2  grains  (0.13  Gm.). 

©  Resin  Podophyllum,  Squibb  bottle,  oz. 

Resina  Podophyllf;  Podophyllin.  An  acid-precipitated,  well- 
washed  resin.  Light-brown  to  greenish-yellow,  faintly  bitter 
powder;  very  irritating  to  the  nose  and  eyes.  Soluble  in 
alcohol.  Slow  but  effective  and  rather  irritant  Cathartic. 
Acts  in  10  to  12  hours.  Average  Dose:  !/£  grain  (0.01  Gm.). 

Resin  Scammony,  Squibb 

(Powdered)  bottle,  oz. 

Resina  ScammonicE.  Prepared  from  best  quality  Turkish  true 
scammony  root,  the  dried  root  of  Convolvulus  Scammonia;  not 
from  the  cheaper,  so-called  "Mexican  scammony  root." 
Yellowish  powder;  faint  odor  and  taste.  Freely  and 
completely  soluble  in  alcohol ;  95  percent,  soluble  in  ether. 
Drastic  Purgative.  Average  Dose :  3  grains  (0.2  Gm.). 


The  Squibb  products  are  recognized  everywhere  as  the  Quality 
Standard.  They  are  of  uniform  purity  and  strength,  hence 
therapeutically  dependable.  When  ordering  or  prescribing  med- 
icinal products,  you  will  do  well  always  to  specify  SQUIBB'S. 


216       SQUIBB'S  MATERIA  MEDICA 

0  Resorcinol,  Squibb 

*Crystals  bottle,  oz. 

Powdered  bottle,  oz. 

Resorcinol;  Resorcin;  Metadihydroxybenzene.  Ce 
Nearly  white  needles  or  powder;  faint  odor;  sweetish  taste, 
bitter  after-taste.  1  Gm.  dissolves  in  0.9  mil  (Cc.)  water  or 
alcohol;  easily  soluble  in  ether  or  glycerin,  very  slightly  in 
chloroform.  Antiseptic  externally;  Antizymotic  internally. 
Employed  internally  in  sea-sickness,  diarrhea,  whooping- 
cough,  cystitis,  etc.;  externally  (in  5  to  30  percent,  solutions  or 
ointments)  in  skin  diseases,  gonorrhea,  etc.  Also  Reagent. 
Average  Dose:  2  grains  (0.13  Gm.).  Incompatible  on  tritura- 
tion  with  aoetanilid,  antipyrine,  camphor,  euphorin,  menthol,  or 
urethane;  with  alkalies  or  spirit  nitrous  ether  in  solution.  Turns 
pink  on  keeping  and  exposure. 

RHAMNUS  FRANCULA.     See  Frangula. 
Rhamnus  Purshiana.        See  Cascara  Sagrada. 
Rhatany.     See  Krameria. 
Rhodalline.     See  Thiosinamine. 

Rhubarb,  Squibb 

*WhoIe  Select  tin,  Ib.         ;  %  Ib. 

Fingers    (Pressed)  80  to  1  Ib.,  per  Ib. 

Ground  for  Percolation  tin,  Ib. 

Powdered  (100)  tin,  Ib.         ;  %  Ib. 

Rheum,  Dried  rhizomes  and  roots  of  Rheum  officinale,  R.  pal- 
matum,  and  other  species  of  Rheum  (Fam.  Polygonaceai). 
Prime  quality  of  Chinese  root,  selected  with  great  care,  all  im- 
perfect and  bad  pieces  being  rejected.  Good  sun-dried  rhubarb 
is  measurably  injured  by  being  sawed  up  into  regular  forms, 
and  therefore  no  "cut  rhubarb"  is  offered  in  this  list.  Char- 
acteristic odor;  bitter,  astringent  taste.  Bitter  Stomachic,  pleas- 
ant Laxative.  Average  Dose:  15  grains  (1  Gm.).  Acts  in  7 
to  8  hours.  (See  also  Extract;  Fluidextract;  Mixture; 
Powder;  Syrup;  Tincture;  Tablets  [Parl  II].). 

RHUS  GLABRA. 

Rhus  Clabra,  N.  F.     Dried,  ripe  fruit  of  Rhus  glabra   (Fam. 

AnacarJiacea).      Astringent,  like    krameria;    in    diarrhea,    etc. 

Average  Dose:  15  grains  (1  Gm.). 

Rochelle  Salt.         See  Potassium  and  Sodium  Tartrate. 
®RosE  (RED). 

Rosa  C allica.     Dried  petals  of  Rosa  gallica   (Fam,  Rosacea), 

Used  pharmaceutically. 

ROSIN. 

Resina;  Colophony.  Residue  left  after  distilling  off  volatile 
oil  from  gum  turpentine.  Freely  soluble  in  alcohol,  ether,  ben- 
zene, oils.  Used  pharmaceutically. 


SQUIBB'S  MATERIA  MEDICA       217 

RUBUS. 

Rubus,  N.  F.;  Blackberry  Bark.  Dried  bark  of  rhizome  of 
Rubus  villosus,  R.  nigrobaccus  or  of  R.  cuneifolius  (Fam. 
Rosacea).  Tannin-bearing  Astringent;  in  diarrhea.  Average 
Dose:  15  grains  (I  Gm.). 

RUFUS'S  PILLS.     See  Pills  Aloes  and  Myrrh. 

RUMEX. 

Rumex,  N.  F.  Roots  of  Rumex  crlspus  or  of  R.  obiusifolius 
(Fam.  Po/ygonacece) .  Alterative.  Average  Dose:  60  grains 
(4  Gm.).  (See  also  Fluidextract). 

SABAL. 

Sabal;  Saw  Palmetto  Berries.  Partially  dried  ripe  fruit  of 
Serenoa  serrulata  (Fam.  Palms).  Used  as  Stimulant  of  genito- 
urinary mucosa,  like  oil  sandalwood.  Average  Dose: 
15  grains  (1  Gm.).  (See  also  Fluidextract.) 

SABROMIN. 

Calcium  Dibrombehenate.  White,  odorless,  tasteless  powder, 
containing  29  percent,  bromine.  Soluble  in  ether;  insoluble  in 
water,  alcohol.  Succedaneum  for  alkali  bromides,  in  same  doses. 

SACCHARIN.     See  Benzosulphinide. 
Saccharin  Soluble.     See  Sodium  Benzosulphinide. 
SACCHARINOSE,    SACCHAROL.      Brands   of   Saccharin. 
SAFFRON.     See  Crocus. 

SAJODIN. 

Calcium  Monoiodobehenate.  (CoiH42lCOO)oCa.  White, 
odorless,  tasteless  powder;  26  percent,  iodine,  4.1  percent,  cal- 
cium. Succedaneum  for  alkali  iodides  internally.  Dose :  5  to 
15  grains  (0.3  to  1  Gm.). 

Sal  Acetosella.  See  Potassium  Binoxalate. 
Sal  Alembroth.  See  Mercury  Ammoniated. 
Sal  Ammoniac.  See  Ammonium  Chloride. 
Sal  Tartar.  See  Potassium  Carbonate. 

Salicin,  Squibb  bottle,  oz. 

Salicinum.  CiaHigOT.  Glucoside  obtained  from  several 
species  of  Salix  and  Populus  (Fam.  Salicacece).  Colorless, 
silky,  shining  needles  or  prisms,  or  white  powder;  odorless, 
very  bitter.  1  Gm.  dissolves  in  23.5  mils  (Cc.)  water,  88.5 
alcohol ;  insoluble  in  ether  or  chloroform.  Antirheumatic,  Anti- 
periodic,  Bitter  Tonic.  Average  Dose:  15  grains  (1  Gm.). 


Since  we  make  only  one  quality  of  each  product,  that  best 
suited  to  the  purposes  intended,  the  specification  "Squibb's" 
is  not  open  to  various  interpretations,  but  has  a  plain,  positive 
meaning.  When  ordering  or  prescribing,  specify  SQUIBB'S. 


218       SQUIBB'S  MATERIA  MEDICA 

SALICYLQUININE.      See    Saloquinine. 

SALIPYRINE. 

Antipyrine  Salicylate.  White,  odorless  powder;  sweetish  taste, 
bitter  after-taste;  about  58  percent,  antipyrine,  32  percent, 
salicylic  acid.  Soluble  in  200  parts  water;  readily  in  alcohol. 
Decomposed  by  acids  and  alkalies.  Analgesic,  Antipyretic. 
Dose:  8  to  30  grains  (0.75  to  2  Gm.). 

Salol.     See  Phenyl  Salicylate. 

SALOPHEN. 

Acetamidosalol.  White,  odorless,  tasteless  powder;  51  per- 
cent, salicylic  acid.  Soluble  in  alcohol,  ether,  chloroform; 
insoluble  in  water.  Decomposed  by  alkalies.  Antirheumatic, 
Antipyretic,  Antiseptic.  Dose:  5  to  15  grains  (0.3  to  1  Gm.). 
Externally  in  10  percent,  ointment. 

SALOQUININE. 

Salicylquinine;  Quinine  Salicylic  Ester.  Whitish,  tasteless, 
odorless  powder.  Soluble  readily  in  chloroform,  sparingly  in 
ether  or  alcohol ;  insoluble  in  water.  Antiperiodic,  Antineural- 
gic,  Antipyretic.  Dose:  5  to  20  grains  (0.3  to  1.3  Gm.). 

Salt,  Bitter.        See  Magnesium  Sulphate. 

Salt,  Carlsbad  Artificial,  Powder,  Squibb 

bottle,   Ib.          ;  |4  Ib. 

Sal  Carolinum  Faclilium,  N.  F.;  dried  form.  2  percent,  potas- 
sium sulphate,  18  sodium  chloride,  36  sodium  bicarbonate,  44 
dried  sodium  sulphate.  16  grains  dissolved  in  7  fluidounces 
water  represents  same  volume  of  Carlsbad  Sprudel  water. 
Saline  Laxative. 

Salt,  Carlsbad  Artificial,  Granular  Effervescent,  Squibb 

bottle,  Ib.          ;  4  oz.  bottles,  per  doz. 

Sal  Carolinum  Faclilium  Effervescent,  N.  F.  26.6  percent, 
dried  artificial  Carlsbad  salt.  Average  Dose:  90  grains  (6 
Gm.). 

Salt,    Epsom.         See  Magnesium  Sulphate. 

Salt,  Glauber's.        See  Sodium  Sulphate. 

Salt,  Kissinger),  Artificial,  Squibb  bottle,  Ib. 

Sal  Kissingense  Factltium,  N.  F.  About  3  percent,  potassium 
chloride,  66  sodium  chloride,  1  1  anhydrous  magnesium  sul- 
phate and  20  sodium  bicarbonate.  Solution  of  24  grains  in 
7  fluidounces  water  represents  same  volume  of  Kissingen  water 
(Rakoczi  spring).  Alterative. 


SQUIBB'S  MATERIA  MEDICA       219 

Salt,     Kissingen,     Artificial,     Granular     Effervescent, 
Squibb  bottle,  Ib.          ;  4-oz.  bottles,  per  doz. 

Sal  Kissingense  Factilium  Effervescens,  N.  F.  Contains  about 
40  percent,  artificial  Kissingen  salt.  Alterative.  Solution  of  80 
grains  in  6  fluidounces  water  represents  equal  volume  of  Kissin- 
gen water.  Average  Dose:  80  grains  (5.5  Gm.). 

Salt,   Monsel's.        See  Iron  Subsulphate. 

Salt,   Rochelle  or  Seignette.          See  Potassium  and  Sodium 
Tartrate. 

Salt,  Vichy,  Artificial,  Squibb  bottle,  Ib. 

Sal  Vichyanum  Faclilium,  N.  F.  Contains  about  85  percent, 
sodium  bicarbonate,  4  potassium  carbonate,  4  anhydrous  mag- 
nesium sulphate,  and  7  sodium  chloride.  Solution  of  16  grains 
in  7  fluidounces  water  represents  equal  volume  of  Vichy  water 
(Grande  Grille  spring).  Antacid. 

Salt,  Vichy,  Artificial,  Granular  Effervescent,  Squibb 

bottle,  Ib.          ;  4-oz.  bottles,  per  doz. 

Sal  Vichyanum  Faclilium  Effervescens,  N.  F.  Contains  25 
percent,  artificial  Vichy  salt.  Solution  of  60  grains  in  7  fluid- 
ounces  water  represents  same  volume  of  Vichy  water  (Grande 
Grille  spring).  Average  Dose:  60  grains  (4  Gm.). 

SALT,    VICHY,    ARTIFICIAL,    GRANULAR    EFFERVESCENT,    WITH 
LITHIUM. 

Sal  Vichyanum  Factitium  Effervescens  cum  Lilhio,  N.  F. 
Contains  25  percent,  artificial  Vichy  salt  and  8.3  percent, 
lithium  citrate.  Antacid.  Average  Dose:  90  grains  (6  Gm.). 

Salt,   Volatile.        See  Ammonium  Carbonate. 
Saltpetre.        See  Potassium  Nitrate. 
SALVARSAN.     Brand  of  Arsph<!namine. 
Salts,  Granular  Effervescent,  Squibb 

Skilfully  made  products,  from  purest  ingredients,  in  accurate 
and  proper  proportions  to  secure  the  best  results.  They  dis- 
solve rapidly  with  brisk  effervescence. 

We  make:  Salt  Carlsbad,  Artificial;  Salt  Kissingen,  Artificial; 
Lithium  Citrate;  Magnesium  Citrate;  Magnesium  Sulphate; 
Sodium  Phosphate;  Sodium  Phosphate  Compound;  Sodium 
Sulphate;  Salt  Vichy,  Artificial.  (See  these  titles.) 


The  founder  of  the  House  of  Squibb,  Dr.  Edward  R.  Squibb, 
not  only  had  high  ideals,  but  lived  and  labored  for  them;  and, 
in  the  words  of  William  Miller  Bartlett,  "the  House  of  Squibb 
stands  today  as  a  living  monument  to  the  honor,  integrity,  zeal 
and  devotion  of  its  founder." 


220        SQUIBB'S  MATERIA  MEDICA 

SAMBUCUS. 

Sambucus,  N.  F.;  Elder  Flowers.  Air-dried  flowers  of  Sam- 
bucus  canadensis  or  of  5.  nigra  (Fam.  Caprifoliacece).  Faintly 
sweet,  aromatic  odor;  slightly  bitter  taste.  Used  in  dropsy; 
large  doses  are  said  to  act  as  Hydragogue  Cathartic.  Average 
Dose:  60  grains  (4  Gm.). 

SANDAL  WOOD. 

Santalum  Album,  N.  F.;  White  or  Yellow  Sandal  Wood. 
Heartwood  of  Santalum  album  (Fam.  Santalacece) .  Aromatic, 
persistent  odor;  strongly  aromatic  taste.  Source  of  oil  sandal 
wood. 

SANDAL  WOOD,  RED. 

» 

Santalum  Rubrum ;  Red  Saunders.  Heart-wood  of  Plero- 
carpus  santalintu  (Fam.  Leguminosee).  Brownish-red  chips 
or  powder;  nearly  odorless  and  tasteless.  Coloring  for  alco- 
holic liquids. 

Sanguinaria,  Squibb 

Ground  for  Percolation  tin,  lb. 

Sanguinaria;    Blood    Root;    Tetterwort.  Dried    rhizome    and 

roots    of    Sanguinaria    canadensis     (Fam.  P  ap  aver  ace  ce).      Of 

slight  odor;   persistent,  acrid  bitter  taste.  Expectorant,  Emetic, 

Errhine.  Average  Dose:  Expectorant,  2  grains  (0.13  Gm.) ; 
emetic,  15  grains  (1  Gm.). 

©  Santonin,  Squibb 

*CrystaIs  bottle,  oz. 

Powdered  bottle,  oz. 

Santoninum.  Anhydride  or  Lactone  of  Santonic  Acid.  CigHigOs^ 
From  Santonica  (Artemisia  pauciflora).  Colorless,  shining, 
flattened,  odorless  prisms,  or  white  pqwder;  nearly  tasteless 
at  first,  then  becoming  bitter.  Turns  yellow  on  exposure  to 
light.  1  Gm.  dissolves  in  43  mils  (Cc.)  alcohol,  1 .7  chloro- 
form, 110  ether;  very  slightly  soluble  jn  water;  soluble  in 
alkalies  and  most  oils.  Vermicide,  especially  against  ascaris. 
Average  Dose:  1  grain  (0.065  Gm.).  Antidotes:  chloral  hy- 
drate by  enema,  cold  affusions. 

SANTYL. 

Santalol  Sahcylate;  Salicylic  Ester  of  Santalol.  Yellowish 
oil;  faint  balsamic  odor  and  taste;  sp.  gr.  1.07.  Soluble  in 
about  10  parts  alcohol;  insoluble  in  water.  Anticatarrhal,  An- 
tiseptic. Dose:  8  to  24  minims  (0.5  to  1.5  mils  [Cc.]),  in 
capsules. 

SARSAPARILLA. 

Sarsaparilla ;  Radix  Sarsee ;  Sarsaparilla  (Fam.  Liliaceai), 
Formerly  used  as  Alterative  in  chronic  rheumatism,  skin  dis- 
eases, syphilis,  etc.;  now  employed  mainly  as  taste  corngent. 
Average  Dose:  30  grains  (2  Gm.).  (See  also  Fluidextract; 
Syrup.) 


SQUIBB'S  MATERIA  MEDICA       221 

Sassafras,  Squibb  tin,  lb. 

Sassafras.  Dried  bark  of  root  of  Sassafras  V or 'ii 'folium  (Fam. 
Lauraceae),  collected  in  early  spring  or  autumn,  and  deprived 
of  outer  corky  layer.  Mild  Aromatic  and  Carminative;  but 
used  chiefly  as  flavoring.  Average  Dose:  2J/2  drachms  (10 
Gm.). 

SASSAFRAS  PITH. 

Sassafras  Medulla,  N.  F..  Dried  pith  of  Sassafras  Variifolium 
(Fam.  Lauracece).  Faint,  sassafras-like  odor;  mucilaginous 
taste.  Demulcent. 

SAXIN.     Brand    of    Benzosulphinide    (Saccharin). 

SCAMMONY    ROOT. 

Scammonite  Radix.  Dried  root  of  Convolvulus  Scammonia 
(Fam.  Convolvulaceai),  yielding  not  less  than  8  percent,  total 
resin.  Hydragogue*  Cathartic.  Average  Dose:  4  grains  (0.25 
Gm.).  (See  also  Resin.) 

SCARLET  R  MEDICINAL: 

Toluylazobetanaphthol.  Dark  brownish-red  powder.  Nearly 
insoluble  in  water;  soluble  in  chloroform,  oils,  fats.  Cicatrizant, 
Antipyic;  in  suppurating  wounds,  chronic  ulcers,  etc.,  in  4  to  8 
percent,  ointments. 

SCOPARIUS. 

Scoparius,  N.  F.;  Broom  Tops.  Dried  tops  of  Cylisus 
scoparius  (Fam.  Leguminosce) .  Diuretic.  Average  Dose:  15 
grains  (1  Gm.). 

®  Scopolamine  Hydrobromide,   Squibb 

1 5-grain  vial,  ;  5-grain  vial, 

Scopolaminae  Hydrobromidum.  Ci7HoiO4N.HBr.3H2O. 
Officially  considered  identical  with  hyoscine  hydrobromide. 
Colorless,  odorless,  slightly  efflorescent  crystals.  1  Gm.  dis- 
solves in  1 .5  mils  (Cc.)  water,  20  alcohol ;  slightly  soluble  in 
chloroform;  insoluble  in  ether.  Hypnotic,  Sedative,  Mydriatic 
(in  J/4  percent,  solution;  also  used  as  preliminary  to  anaesthesia, 
and  combined  with  morphine,  to  produce  "twilight  sleep." 
Average  Dose :  ViOO  grain  (0.0003  Gm.) ;  in  the  insane 
larger  doses  are  given.  Antidotes:  tannin,  emetics;  pilocarpine 
or  morphine  subcutaneously ;  chloral  hydrate.  (See  also  Tab- 
lets [Part  II].) 

SCOPOLAMINE,  STABLE. 

Scopomannit.  Aqueous  solution  scopolamine  hydrobromide  pro- 
tected against  decomposition  by  addition  of  JO  percent,  man- 
nit..  1  mil  (Cc.)  contains  0.0003  Gm.  (1/200  grain)  drug. 


The  Squibb  -Ideals  have  taken  concrete  form  in  the  Squibb 
Products;  these  are  universally  recognized  as  standards  of 
uniform  Purity  and  Efficacy,  that  is,  general  Excellence  and 
Reliability.  Specify  SQUIBB'S  when  prescribing  or  ordering. 


222        SQUIBB'S  MATERIA  MEDICA 

SCULLCAP.     See   Scutellaria. 

SCUTELLARIA. 

Scutellaria,  N.  F.;  Scullcap;  Hoodwort.  Dried  plant  of 
Scutellaria  lateriflora  (Fam.  Labials).  Bitter  taste;  contains 
several  proximate  principles.  Used  as  Nerve  Sedative,  Anti- 
spasmodic;  in  chorea,  convulsions,  neuralgia,  etc.  Average 
Dose:  15  grains  (1  Gm.). 

Seidlitz  Powder.        See  Powder,  Seidlitz. 

SENECIO. 

Senecio  Aureus,  N.  F. ;  Life  Root.  Dried,  overground  por- 
tions of  Senecio  aureus  (Fam.  Composites).  Aromatic  odor; 
bitter,  slightly  astringent,  acrid,  pungent  taste.  Used  as  Tonic, 
Expectorant,  Diaphoretic,  Diuretic.  Average  Dose:  60  grains 
(4  Gm.). 

SENECIO. 

Senecio,  N.  F.;  Life  Root.  Dried  overground  portions  of 
Senecio  aureus  (Fam.  Composites).  Used  as  Tonic,  Diuretic, 
Expectorant,  Diaphoretic.  Average  Dose:  60  grains  (4  Gm.). 

SENEGA. 

Senega ;  Senega  Snakeroot.  Dried  root  of  Polygala  Senega 
(Fam.  Polygalacete) ;  of  correct  identity  and  purity.  Odor 
slight,  nauseating;  taste*  sweetish,  afterwards  acrid.  Nauseant 
Expectorant.  Average  Dose:  15  grains  (1  Gm.)-  (See  also 
Fluidextract;  Syrup.) 

©  Senna,  Squibb  *Whole  tin,  Ib. 

Ground  for  Percolation  tin,  Ib. 

Powdered  tin,  Ib. 

Senna.  Alexandria  and  India  senna,  respectively  the  dried 
leaflets  of  Cassia  acutifolia  and  C.  angustifolia  (Fam.  Legum- 
inos<e).  Cathartic.  Average  Dose:  60  grains  (4  Gm.).  Acts 
in  4  to  5  hours.  (See  also  Confection;  Fluidextract;  Syrup.) 

SERPENTARIA. 

Scrpentaria;  Virginia  Snakeroot.  Dried  rhizome  and  roots  of 
Arislolochia  Serpenlaria  and  A.  reliculata  (Fam.  Arisioloch- 
f'acece).  Bitter,  similar  to  gentian.  Average  Dose:  15  grains 
(1  Gm.). 

Serum  Antidiphtheritic  and  Serum  Antitetanic. 

See   Part   III,    Biological    Products. 

SILICA. 

Terra  Silicea  Purificala;  Purified  Kieselguhr;  Purified  Infusor- 
ial Earth.  SiOo  consisting  of  frustules  and  fragments  of  di- 
atoms purified  by  boiling  with  hydrochloric  acid.  Fine,  bulky, 
white  or  light-gray,  odorless,  tasteless,  insoluble  powder.  Fil- 
tering medium,  particularly  for  acid  solutions. 


SQUIBB-'S  MATERIA  MEDICA       223 

SILVER  CITRATE. 

White,  odorless,  heavy  powder.  Soluble  in  about  3800  parts 
water.  Astringent  and  Bactericide,  like  silver  nitrate. 

Silver  Colloidal.     See  Solargentum. 

®  Silver  Nitrate,  Squibb 

Crystals  or  "Granulated  bottle,  oz. 

Argenli  Nilras.  AgNOs.  Colorless,  transparent,  odorless, 
crystals  or  granules;  bitter,  caustic,  metallic  taste.  Darkens  on 
exposure  to  light.  1  Gm.  dissolves  in  0.4  mil  (Cc.)  water,  30  mils 
alcohol.  Incompatible  with  alkalies,  bromides,  iodides,  chlor- 
ides, hypophosphites,  alkaloidal  salts,  tannic  acid  in  solution; 
with  vegetable  infusions,  tinctures,  and  decoctions;  with  all 
organic  substances  and  reducing  agents.  Dispense  solutions  in 
black  bottles.  Escharotic,  Astringent,  Antiseptic.  Average 
Dose:  */6  grain  (0.01  Gm.).  Antidotes:  White  of  egg  or  milk; 
emetics  subcutaneously;  sodium  or  ammonium  chloride.  (See 
also  Reagents  [Part  IV];  Tablets  [Part  II].) 

Silver  Nitrate  1  °/o   Solution,  Squibb 

box  of  1  dozen  Ampuls, 

For  prevention  of  ophthalmia  neonatorum,  1  or  2  drops  being 
instilled  into  each  eye. 

Silver  Nitrate  Crayons,  Squibb  bottle  of  100, 

Small  crayons  of  pure  silver  nitrate,  about  1/lfi  in.  thick  and  */4 
in.  long.  Especially  designed  for  genito-urinary  surgeons,  and 
affording  a  convenient,  sanitary  means  of  cauterization,  each 
crayon  serving  for  one  application  only.  Used  in  an  applicator. 

Silver  Nitrate  Mitigated,  Squibb  bottle,  oz. 

Argenti  Nitras  Miligalus,  U.  S.  P.  VHIth  Rev.;  Silver  Nitrate 
Diluted.  66.7  percent,  potassium  nitrate,  33.3  percent,  pure 
silver  nitrate.  Its  constituents  retain  the  solubility  in  water 
and  in  alcohol  characteristic  respectively  of  silver  nitrate  and 
potassium  nitrate.  Being  made  from  pure  materials,  the  pro- 
duct is  free  from  all  prohibited  contaminations.  Used  ex- 
ternally where  moulded  silver  nitrate  is  too  powerful. 

Silver  Nitrate  Moulded,  Squibb  bottle,  oz. 

Argenti  Nilras  Fusus;  Lunar  Caustic.  Pure  silver  nitrate 
melted  with  approximately  4  percent,  hydrochloric  acid  and 
moulded  into  small  cones.  Caustic,  on  warts,  sluggish  ulcers. 


The  Squibb  Label  on  a  package  is  a  positive  guaranty  for  the 
uniform  Purity  and  Reliability  of  the  product.  We  make  only 
ONE  quality:  the  SQUIBB  quality;  and  our  prices  are  as  low 
as  they  can  be  made  for  that  quality.  Specify  SQUIBB'S. 


224       SQUJBB'S  MATERIA  MEDICA 

SlOMINE. 

Hexamethylenamine  Tetraiodide.  (Cr^oN-iL;.  White  pow- 
der; slight  odor  and  taste;  78.5  per  cent,  iodine;  almost  insolu- 
ble in  water  or  alcohol.  Succedaneum  for  potassium  iodide. 
Dose:  3  to  15  grains  (02  to  1  Gm.). 

SMITH'S  SOLUTION  BROMINE.    See  Solution  Bromine. 
SNAKE-ROOT,  BLACK.    See  Cimicifuga. 
SNAKE-ROOT,  CANADA.    See  Asarum. 
SNAKE-ROOT,  SENECA.    See  Senega. 
SNAKE-ROOT,  VIRGINIA.     See  Serpentaria. 

©  Soap    Powdered,    Squibb  bottle,  lb.         ;  |4  lb. 

Sapo ;  Castile  Soap.  Powderd  hard  soap,  prepared  from 
sodium  hydroxide  and  olive  oil.  Soluble  in  water  and  alcohol. 
Laxative,  antidote  for  acid  poisons. 

0  Soap  Soft,  Squibb  jar,  lb.         ;  ]4  lb. 

Sapo  Mollis;  often  erroneously  called  "Green  Soap."  The  U. 
S.  P.  now  directs  this  soap  to  be  made  with  cotton-seed  oil, 
which  was  always  used  by  the  Squibb  Laboratories  because 
yielding  a  better  soap  than  linseed  oil.  The  Squibb  soft 
soap  has  therefore  been  generally  recognized  as  an  excellent 
article.  It  is  free  from  disagreeable  odor,  is  of  clear  yellow 
color,  contains  no  green  coloring-matter,  and  is  uniformly 
alkaline  to  the  extent  of  no  more  than  0.25  percent,  of  caustic 
alkali.  Detergent,  Antipruritic;  in  parasitic  skin  diseases,  etc. 

Soap  Soft,  Liquid,  Squibb          lb.         ;  J/2  lb.         ;  %  lb. 

Preceding  product   rendered   liquid   by   addition   of  water. 

SOAP  BARK.     See  Quillaja. 

Soda,  Caustic.        See  Sodium  Hydroxide. 

SODA  MINT.     See  Solution  Soda  and  Mint. 

SODA  WITH  LIME. 

Soda  cum  Calce,  N.  F.;  London  Paste.  Equal  parts  sodium 
hydroxide  and  calcium  oxide,  powdered.  Caustic.  Keep  well 
stoppered,  in  dry  place. 

Sodium  Acetate  Crystals,  Reagent. 
See   Reagents    (Part   IV). 

Sodium  Acetate  (Dried),  Squibb  tin,  lb. 

Sodii  Acetas.  NaC^^^Oo.  Anhydrous;  not  official,  crystal- 
line salt  with  three  molecules  of  water.  White  powder;  cool- 
ing, saline  taste.  Of  best  medicinal  efficacy,  and  superior  for 
compounding  and  dispensing  purposes.  Freely  soluble  in  water, 
less  readily  in  alcohol.  Diuretic;  also  used  in  photography. 
Ordinary  Dose:  10  grains  (0.65  Gm.).  (See  also  Reagents, 
Part  IV.) 


SQUIBB'S  MATERIA  MEDICA       225 

Sodium  Acid  Phosphate.       See  Sodium  Phosphate,  Acid. 
SODIUM  ARSANILATE.    See  Atoxyl. 

©  Sodium  Arsenate  (Cryst.),  Squibb  bottle,  oz. 

SoJii  Arsenas.  Na2HAsO4.7H2O.  Colorless,  transparent, 
odorless  prisms;  mild,  alkaline  taste;  efflorescent  in  dry  air, 
slightly  deliquescent  in  moist  air.  I  Gm.  dissolves  in  1 .5  mils 
(Cc.)  water,  2  glycerin;  sparingly  soluble  in  alcohol.  Alter- 
ative, Antiperiodic ;  in  malaria,  nervous  diseases,  skin  affec- 
tions, rheumatism,  etc.;  also  used  in  cigarettes  for  asthma  and 
phthisis,  and  as  Reagent.  Dose:  !/12  grain  (0.005  Gm.). 
Antidotes:  arsenic  antidote,  or  milk  with  magnesia;  then 
emetics. 

Sodium  Arsenate  Exsiccated,  Squibb  bottle,  oz. 

Sodii  Arsenas  Exsiccalus.  Preceding  article  deprived  of  its 
crystal  water.  White,  odorless,  amorphous,  slightly  hygroscopic 
powder.  1  Gm.  dissolves  in  3.1  mils  (Cc.)  water;  slightly 
soluble  in  alcohol.  Average  Dose:  i/so  grain  (0.003  Gm.). 

Sodium  Arsenite,  Squibb  bottle,  oz. 

NaAsC>2.  Grayish-white  powder.  Soluble  in  water,  slightly 
in  alcohol.  Uses  chiefly  technical. 

©Sodium  Benzoate,  Squibb 

*From  Synthetic  Acid  tin,  ^4  HJ.        oz. 

.From  Natural  (True)  Acid  bottle,  oz. 

Sodii  Benzoas.  NaCyHsC^.  White,  nearly  odorless  powder; 
sweetish  taste.  1  Gm.  dissolves  in  1.8  mils  (Cc.)  water,  61 
alcohol.  Mild  Antiseptic;  in  cystitis,  tonsillitis,  colds,  etc. 
Average ^Dose:  15  grains  (1  Gm.).  Incompatible  with  mineral 
acids,  ferric  salts. 

Sodium  Benzosulphinide,  Squibb  bottle,  oz. 

Sodii  Benzosulphinidum  ;  Soluble  Saccharin;  Sodium-Sac- 
charin. White,  odorless,  intensely  sweet  powder.  1  Gm.  dis- 
solves in  1.2  mils  (Cc.)  water,  50  alcohol.  Non-fermentable 
sweetener;  taste  corrigent  for  bitter  or  acrid  drugs.  About  380 
times  as  swe'et  as  cane  sugar. 

Sodium    Biborate.     See    Sodium   Borate. 

©  Sodium  Bicarbonate,  Squibb    tin,  lb.         ;  '/£  lb.        J4  N>. 

Sodii  Bicarbonas.  NaHCO,3.  Conforming  to  the  most  rigid 
demands  for  purity.  Uniformly  fine,  bolted  powder.  The 
absence  of  sodium  carbonate  renders  it  free  from  the  bitter 


This  house  supplies  only  one  quality  of  each  product:  that  best 
suited  to  the  purposes  intended.  The  specification  "Squibb's" 
is  not  open  to  various  interpretations;  it  has  a  plain,  posi- 
tive meaning.  When  prescribing,  please  specify  SQUIBB'S. 
B 


226       SQUIBB'S  MATERIA  MEDICA 

0Sodium  Bicarbonate,  Squibb  (Cont.) 

taste  noticeable  when  even  small  traces  of  latter  are  present, 
as  in  the  ordinary  grades.  1  Gm.  dissolves  in  10  mils  (Cc.) 
water  (boiling  water  changes  it  to  carbonate) ;  insoluble  in 
alcohol.  Antacid;  Antipruritic  topically.  Average  Dose:  15 
grains  (1  Gm.) ;  in  iodism  and  diabetic  coma  larger  doses  (2 
ozs.  or  more  daily)  are  given.  Incompatible  with  acids,  acid 
salts,  bismuth  subnitrate,  etc.  (See  also  Reagents  [Part  IV].) 

Sodium  Biphosphate.       See  Sodium  Phosphate,  Acid. 

Sodium  Bisulphate,  Squibb  bottle,  IB.         ;  \/j,  lb. 

NaHSO-j.HoO.  Pure,  colorless  crystals.  Soluble  in  water. 
Used  largely  in  typhoid  fever,  and  as  purifier  of  drinking  water 
in  typhoid  regions.  Dose:  15  grains  (1  Gm.)  every  few  hours, 
with  water.  (See  also  Reagents  [Part  IV].) 

Sodium  Bisulphite  Reagent.       See  Reagents  (Part  IV). 

Sodium  Bitartrate,  Squibb  bottle,  Ib.          ;  |4  lb. 

NaHC4H4Oe.H2O.  Small,  white  crystals,  or  white  crystal- 
line powder.  1  Gm.  dissolves  in  about  9  mils  (Cc.)  water. 
Refrigerant,  Aperient.  Dose:  30  to  60  grains  (2  to  4  Gm.). 
(See  also  Reagents  [Part  IV].) 

®  Sodium  Borate,  Squibb 

(Powdered)  tin,  lb.         ;  %  lb. 

Sodii  Boras;  Borax;  Sodium  Biborate.  NaoB^v.lOHoO.  A 
special  medicinal  quality.  I  Gm.  dissolves  in  15  mils  (Cc.) 
water,  about  I  mil  glycerin;  insoluble  in  alcohol.  Alkaline 
Antiseptic  Detergent  and  Astringent,  externally;  rarely  used 
internally,  as  Emmenagogue  and  Antiepileptic.  Dose:  12  grains 
(0.75  Gm.).  Incompatible  with  acids,  alkaloidal  and  metallic 
salts  in  solution,  mucilage  acacia,  etc.  (See  also  Reagents 
[Part  IV].) 

SODIUM  BORO-BENZOATE. 

SoJii  Boro-Benzoas,  N.  F.  43%  sodium  borate,  57  '/r  sodium 
benzoate.  Alkaline  Antiseptic.  Average  Dose:  30  grains 
(2  Gm.). 

©  Sodium  Bromide,  Squibb 

(Granular)  bottle,  lb.         ;  1/4  lb. 

SoJi'i  BromiJum.  NaBr.  White  granular  powder;  saline, 
slightly  bitter  taste.  1  Gm.  dissolves  in  1.1  mils  (Cc.)  water, 
16  alcohol.  Incompatible  with  acids,  alkaloidal  and  metallic 
salts  in  solution.  Nerve  Sedative,  Cerebral  Depressant.  Aver- 
age Dose:  15  grains  (1  Gm.).  Absorbed  and  eliminated 
slowly,  and  where  long  continued  should  be  omitted  for  a  few 
days  in  every  month. 


SQUIBB'S  MATERIA  MEDICA       227 

®  Sodium  Cacodylate,  Squibb  oz.  vial      ;  '/8  oz. 

Sodii  Cacodylas;  Sodium  Dimethylarsenate.  Na(CHs)2As- 
O2-3H2O.  Small,  colorless,  hygroscopic  crystals;  faint  gar- 
licky odor.  I  Gm.  dissolves  in  about  0.5  mil  (Cc.)  water;  2.5 
mils  alcohol;  sparingly  in  ether,  chloroform.  Contains  35 
percent,  arsenic  (equivalent  to  47  percent,  arsenous  acid). 
Alterative,  Hematinic;  like  arsenous  acid,  but  relatively  non- 
toxic.  Used  mainly  hypodermically  in  anemias,  syphilis, 
chronic  skin  diseases,  diabetes,  etc.  Average  Dose:  I  grain 
(0.065  Gm.);  in  syphilis,  7  grains  (0.45  Gm.),  every  second 
day  or  daily,  by  intramuscular  injection  or  subcutaneously. 
(See  also  Ampuls.) 

Sodium    Carbonate    Anhydrous    Reagent,    and    Sodium 
Carbonate  Crystals  Reagent.     See  Reagents  (Part  IV.) 

Sodium  Carbonate  Dried,  Squibb  tin,  lb. 

NaoCOs^HoO.  Contains  about  75  percent,  anhydrous  sodium 
carbonate.  Antacid,  Antipruritic;  used  largely  pharmaceutical- 
ly  and  technically.  Dose:  5  to  10  grains  (0.3  to  0.6  Gm.). 

0  Sodium  Carbonate  Monohydrated,  Squibb     bot.,  lb. 

Sodii  Carbonas  M  onohydratus.  Na2CC>3.H2O.  White,  crystal- 
line powder;  odorless,  strongly  alkaline  taste.  1  Gm.  dissolves 
in  3  mils  (Cc.)  water,  7  glycerin;  insoluble  in  alcohol  or  ether. 
Antacid,  Antipruritic,  like  sodium  bicarbonate,  but  seldom  used 
internally;  also  Reagent.  Externally  in  2  to  5  percent,  solu- 
tions or  1 :8  ointment  in  skin  diseases.  Average  Dose :  4  grains 
(0.25  Gm.),  well  diluted.  Incompatible  with  acids,  acid  salts, 
heavy  metals  and  alkaloids,  etc.  Antidotes:  acetic  acid  or 
lemon  juice;  olive  oil. 

Sodium  Chlorate,  Squibb 

(Granular)  tin,  lb.         ;  YA  lb.         ;  oz. 

Sodii  Chloras,  U.  S.  P.  Vlllth  Rev.  NaClOs.  Colorless 
odorless,  granular  salt;  cooling,  saline  taste.  Soluble  in  1  part 
water,  100  alcohol,  5  glycerin.  Antiseptic,  Astringent,  Anti- 
sialagogue,  externally;  Alterative,  internally,  like  potassium 
chlorate.  Average  Dose:  4  grains  (0.25  Gm.).  Explosion  may 
occur  when  sodium  chlorate  is  heated  or  subjected  to  concus- 
sion or  trituration  with  organic  substances  (cork,  tannic  acid, 
sugar,  etc.),  or  with  sulphur,  antimony  sulphide,  phosphorus,  or 
other  easily  oxidizable  substances.  Antidotes:  emetics,  diuretics; 
ice;  opium;  pilocarpine;  caffeine  subcutaneously.  (See  also  Re- 
agents [Part  IV].) 


The  prices  of  the  Squjbb  Products  are  in  all  instances  as  low  as 
the  quality  and  quantity  of  ingredients  and  the  expense  of  man- 
ufacture a  I  low.  They  include  containers,  packing  and  boxing.  When 
ordering  or  prescribing  medicinal  products,  specify  SQUIBB'S. 


228       SQUIBB'S  MATERIA  MEDICA 

0  Sodium  Chloride,  Squibb  bottle,  Ib. 

Sodii  Chloridum.  NaCI.  Highly  purified,  for  use  in  transfu- 
sion, hypodermoclysis,  and  other  cases  where  an  especially  pure 
product  is  required.  The  chlorides  and  sulphates  of  calcium 
and  magnesium,  and  other  impurities,  have  been  removed.  1 
Gm.  dissolves  in  2.8  mils  (Cc.)  water,  10  glycerin;  almost  in- 
soluble in  alcohol.  Occasionally  used  as  Emetic.  Average 
Dose:  240  grains  (15  Gm.).  (See  also  Reagents  [Part  IV]; 
Tablets,  Salt  [Part  II].) 

Sodium  Citrate,  Squibb  bottle,  Ib.        ;  14  Ib. 

Sodii  Cilras.  NasCeHsOy^HaO.  White,  odorless,  granu- 
lar powder;  efflorescent  in  dry  air;  cooling,  saline  taste.  1 
Gm.  dissolves  in  1.3  mil  (Cc.)  water;  insoluble  in  alcohol. 
Systemic  Alkali,  Diuretic.  Average  Dose:  15  grains  (1  Gm.). 
(See  also  Reagents  [Part  IV] ;  Tablets  [Part  II].) 

SODIUM  CYANIDE. 

Sodii  Cyanidum.  Newly  official.  NaCN.  White,  opaque 
pieces;  or  white,  granular  powder;  odorless  when  dry,  but  ex- 
haling odor  of  hydrocyanic  acid  when  damp.  Freely  soluble 
in  water.  Cough  Sedative,  Antispasmodic.  Ordinary  -Dose: 
Ve  grain  (0.01  Gm.).  Antidotes:  chlorine  water  or  chlor- 
inated-soda solution,  emetics;  solution  hydrogen  peroxide  hypo- 
dermically;  ammonia;  artificial  respiration. 

Sodium  Cyanide  Reagent.       See  Reagents  (Part  IV). 
SODIUM  DlETHYLBARBlTURATE.     See  Barbital-Sodium. 
Sodium  Dimethylarsenate.        See  Sodium  Cacodylate. 

Sodium  Glycerophosphate  (Dry),  Squibb 

bottle,  Ib.          ;  %  Ib.          ;  oz. 

Sodii  Clycerophosphas.  Hydrated  Sodium  Glycerophosphate 
containing  not  less  than  68  percent,  anhydrous  NaoCsHjPOg. 
White,  odorless  powder;  saline  taste.  Soluble  freely  in  water; 
almost  insoluble  in  alcohol.  Used  as  Nerve  Tonic,  and  usually 
given  with  other  glycerophosphates.  Average  Dose:  4  grains 
(0.25  Gm.).  (See  also  Elixir;  Solution;  Tablets  [Part  II]). 

SODIUM    GLYCEROPHOSPHATE   50%.      See   Solution   Sodium   Gly- 
cerophosphate. 

Sodium   Glycocholate,   Squibb 

1  -oz.  vial,  ;  '/g-oz.  vial, 

One  of  the  bile  salts.  Greenish-black,  very  bitter  granules; 
peculiar  odor.  Soluble  in  water  or  alcohol  with  turbidity. 
Cholagogue.  Dose:  5  to  15  grains  (0.3  to  1  Gm.),  as  tablets. 
(See  also  Tablets  [Part  II].) 


SQUIBB'S  MATERIA  MEDICA        229 

©  Sodium  Hydroxide,  Squibb  bottle,  lb.  ;  J4  lb. 
Sodii  Hydroxidum  ;  Sodium  Hydrate;  Soda;  Caustic  Soda. 
NaOH.  Electrolytic;  exceptionally  pure,  and  assays  higher 
than  U.  S.  P.  requirements  of  90  percent.  Small,  white, 
crushed  lumps.  1  Gm.  dissolves  in  0.9  mil  (Cc.)  water;  very 
soluble  in  alcohol.  Caustic,  Antacid.  Dose:  */2  *°  I  grain 
0.03  to  0.065  Gm.)  well  diluted.  Antidotes:  water,  then  vinegar 
or  lemon  juice,  followed  by  emetics;  demulcents.  NOTE:  On 
exposure  sodium  hydroxide  deliquesces,  absorbs  carbon  dioxide 
and  becomes  coated  with  carbonate.  Hence  keep  well-stop- 
pered, in  dry  place.  (See  also  Reagents  [Part  IV] ;  Solution.) 

Sodium  Hypophosphite,  Squibb 

bottle,  lb.          ;   %  lb.          ;   oz. 

Sodii  Hypophosphis.  NaPHoO2.H2O.  Small,  colorless 
plates,  or  white  granular  powder;  odorless;  bitterish-sweet, 
saline  taste;  deliquescent  in  moist  air.  1  Gm.  dissolves  in  1 
mil  (Cc:)  water,  2  mils  glycerin;  soluble  in  alcohol;  insoluble 
in  ether.  Ingredient  of  hypophosphite  mixtures  used  as  Tonics. 
Average  Dose:  15  grains  (1  Gm.).  Care  should  be  observed 
in  dispensing  this  salt,  as  explosion  may  occur  when  it  is  tritur- 
ated or  heated  with  nitrates,  chlorates  or  other  oxidizing  agents. 

Sodium  Hyposulphite.        See  Sodium  Thiosulphate. 


0  Sodium  Iodide,  Squibb  bottle,  oz. 

Sodii  lodidum.  Nal.  Made  by  a  special  Squibb  process. 
White,  odorless,  crystalline  powder;  saline,  slightly  bitter  taste; 
deliquescent  in  moist  air.  1  Gm.  dissolves  in  0.55  mil  (Cc.) 
water,  about  2  mils  alcohol,  1  glycerin.  Alterative,  Resolvent, 
Saline  Expectorant,  like  potassium  iodide.  Average  Dose :  5 
grains  (0.3  Gm.).  Incompatible  with  many  alkaloidal  salts, 
spirit  nitrous  ether,  potassium  chlorate,  acids,  bismuth  and  ferric 
salts,  etc. 

Sodium  Nitrate,  Squibb  bottle,  lb.    • 

Chili  Saltpetre.  NaNO3.  Dropped  from  U.  S.  P.  Colorless, 
granular  salt;  cooling,  saline,  slightly  bitter  taste;  hygroscopic 
in  moist  air.  Soluble  in  about  1.1  parts  water,  100  alcohol. 
Rarely  used  in  human  medicine,  at  present;  in  intestinal 
catarrhs,  rheumatism,  dropsy,  etc.  Ordinary  Dose:  15  grains  (1 
Gm.)  well  diluted.  Externally  (in  rheumatism),  in  1  :3  solu- 
tion. Antidotes:  stimulants;  ice  water;  opium.  (See  also 
Reagents  [Part  IV].) 


jf  difficulty  is  experienced  in  procuring  any  Squibb  product, 
in  the  original  packages  here  listed,  please  notify  us;  we 
shall  see  that  your  wants  are  met  promptly  and  satisfactorily. 


230       SQUIBB'S  MATERIA  MEDICA 

0  Sodium  Nitrite,  Squibb          bottle,  |4  'b-          ;  °7- 

Sodii  Nitris.  95%  NaNOg.  White  granules;  odorless;  mild, 
saline  taste.  I  Gm.  dissolves  in  1.5  mils  (Cc.)  water;  slightly 
soluble  in  alcohol.  Vaso-dilator,  similar  to  nitroglycerin  but 
slower  and  more  prolonged.  Average  Dose:  1  grain  (0.065 
Gm.).  Incompatible  in  solution  with  acetanilid,  antipyrine, 
hypophosphites,  iodides,  vegetable  infusions,  decoctions  or  tinc- 
tures, or  mercury*  salts.  Keep  well  stoppered;  on  exposure  it 
deliquesces  and  is  oxidized  to  nitrate.  (See  also  Reagents 
[Part  IV] .) 

Sodium  Nitroprusside  Reagent.    See  Reagents  (Part  IV). 
Sodium  Oxalate  Reagent.       See  Reagents  (Part  IV). 

SODIUM  PERBORATE. 

Sodii  Perboras.  NaBOs^HoO.  White,  granular,  odorless 
salt.  Soluble  in  water,  decomposing  into  hydrogen  peroxide 
and  sodium  metaborate.  Antiseptic,  Deodorant,  Bactericide;  in 
2%  solution  or  as  dusting  powder,  on  purulent  wounds,  etc. 

Sodium  Peroxide  Reagent.       See  Reagents  (Part  IV). 
Sodium  Phenolsulphonate,  Squibb  bottle,  oz. 

Sodii  Phenolsulphonas;  Sodium  Sulphocarbolate.  CgHsO.- 
SOsNa.2H2O.  It  is  a  very  difficult  matter  to  make  an  article 
of  correct  chemical  identity  and  satisfactory  purity.  The  product 
quoted  contains  the  officially  required  99  percent,  pure  sodium 
paraphenolsulphonate.  White  or  nearly  white  powder;  cool- 
ing, saline,  bitter  taste;  slightly  efflorescent.  1  Gm.  dissolves 
in  4.2  mils  (Cc.)  water,  140  alcohol,  about  5  glycerin.  Used 
as  Intestinal  Antiseptic;  mostly  internally  in  typhoid  fever, 
fermentative  dyspepsia,  phthisical  diarrhea,  etc.  Average 
Dose:  4  grains  (0.25  Gm.).  Externally  in  %  to  1  percent, 
solution;  in  gonorrhea,  putrid  wounds,  etc. 

©  Sodium  Phosphate,  Squibb 

(Granular)  tin,  Ib.         ;  l/2  lb.         ;  %  Ib. 

bottle,  lb.          ;  J/2  lb.          I  !4  lb. 

$odii  Phosphas;  Disodium  Orthophosphate.  NaoHPC^.^HoO. 
Much  of  the  sodium  phosphate  on  the  market  contains  arsenic 
in  quantities  sufficient  to  render  its  use  dangerous.  The  article 
here  listed  has  been  recrystallized  and  purified  until  no  trace 
of  arsenic  can  be  detected  in  5  Gm.  by  the  Marsh-Berzelius 
test  in  l/o  hour.  Colorless;  odorless;  cooling,  saline  taste.  Very 
efflorescent.  1  Gm.  dissolves  in  2.7  mils  (Cc.)  water;  insoluble 
in  alcohol.  Incompatible  with  solutions  of  alkaloidal  salts,  and, 
on  trituration,  with  antipyrine,  phenol,  chloral  hydrate,  resorcin, 
salicylic  acid  or  sodium  salicylate.  Keep  well  closed,  in  cool 
place.  Saline  Cathartic,  similar  to  magnesium  sulphate  (epsom 
salt).  Average  Dose:  60  grains  (4  Gm.) ;  as  much  as  240 
grains  (16  Gm.)  is  often  given.  (See  also  Reagents  [Part 
IV].) 


SQUIBB'S  MATERIA  MEDICA       231 

0  Sodium  Phosphate,  Acid,  Squibb 

bottle,  Ib.         ;  |4  lb.          ;  oz. 

Sodium  Biphosphate;  Monosodium  Dihydrogen  Phosphate. 
NaHsPO-j-j-aq.  Colorless,  slightly  hygroscopic  granules;  acid 
reaction.  Soluble  in  less  than  1  part  water;  insoluble  in  al- 
cohol. Urine-acidifier,  usually  given  in  conjunction  with  hexa- 
methylenamine  as  urinary  bactericide  administered  two  hours 
before  latter  drug.  Dose:  15  to  20  grains  (1  to  1.3  Gm.), 
in  sweetened,  flavored  solution,  as  often  as  required  to  render 
urine  acid. 

®  Sodium  Phosphate,  Granular  Effervescent,  Squibb 

bottle,  lb.          ;  4-oz.,  per  doz. 

Sodii  Phosphas  Effervescent.  20  percent,  exsiccated  sodium 
phosphate.  Average  Dose:  150  grains  (10  Gm.). 

Sodium  Phosphate  Compound,  Granular  Effervescent, 
Squibb  4-oz.  bottles  with  dose-measures,  per  doz. 

Formerly  called  G.  E.  Antilithic.  Suggested  by  Dr.  H.  H. 
Tinker,  of  New  York,  as  an  agreeable  and  efficient  Eliminant 
in  gout,  rheumatism  and  all  conditions  connected  with  the  uric 
acid  diathesis.  Each  drachm  contains  5  grains  Dried  Sodium 
Phosphate,  and  1  grain  each  Sodium  Benzoate  and_  Sodium 
Salicylate  True,  all  of  the  Squibb  quality.  Ordinary  Dose: 
2  drachms  (8  Gm.). 

Sodium  Phosphate  Exsiccated,  Squibb 

bottle,  lb.          ;  |4  lb. 

SoJii  Phosphas  Exsiccaius;  Dried  or  Anhydrous  Sodium  Phos- 
phate. Na^HPO4.  Crystalline  sodium  phosphate  is  very  apt 
to  effloresce  and  become  uncertain  in  dosage.  This  disadvantage, 
combined  with  the  largeness  of  the  dose,  has  created  a  prefer- 
ence for  the  dried  salt,  the  dose  of  which  is  only  one-half  that 
of  the  granular  salt.  Exceedingly  hygroscopic,  hence  must  be 
kept  well  stoppered  and  in  a  dry  place. 

Sodium  Phosphate  Liquefied.       See  Solution  Sodium  Phos- 
phate  Compound. 
Sodium  Pyrophosphate,  Squibb 

tin,  lb.          ;  %  lb.          ;  oz. 

Sodii  Pyrophosphas,  U.  S.  P.,  VHIth  Rev.  Na4PoO7.]OHoO. 
Colorless,  odorless,  transparent  prisms,  or  white  powder,  of 
cooling,  saline,  feebly  alkaline  taste;  slightly  efflorescent.  Sol- 
uble in  about  1 1 .5  parts  water ;  insoluble  in  alcohol.  Laxative, 
similar  to  sodium  phosphate.  Average  Dose:  30  grains  (2  Gm.). 

®  Sodium  Salicylate,  Squibb 

*  From  Synthetic  Acid,  Powdered 

tin,  lb.          ;  %  lb.          ;  oz. 
Sodii  Salicylas.     NaCyHoOa.     White  or  faintly  pinkish  pow- 

The  Squibb  products  are  recognized  everywhere  as  the  Quality 
Standard.  They  are  of  uniform  purity  and  strength,  hence 
therapeutically  dependable.  When  ordering  or  prescribing  me- 
dicinal products,  you  will  do  well  always  to  specify  SQUIBB'S. 


232        SQUIBB'S  MATERIA  MEDICA 

©Sodium  Salicylate,  Squibb  (Cent.) 

der;  odorless  or  nearly  so;  sweetish,  saline  taste.  1  Gm.  dis- 
solves in  0.9  mil  (Cc.)  water,  92  alcohol;  soluble  also  in 
glyycerin.  Antirheumatic,  Antineuralgic,  Antiseptic.  Aver- 
age Dose:  15  grains  (1  Gm.).  Incompatible  with  ferric  salts, 
acids,  and  acid  salts,  quinine  salts  in  solution,  etc.  (See  also 
Tablets  [Part  II].) 

Sodium  Salicylate  from  Natural  (True)  Acid,  Squibb 

(Powdered)  bottle,  Ib.          ;  %  Ib.          ;  oz. 

Prepared  with  natural  (true)  salicylic  acid  derived  from  pure 
oil  betula.  Believed  by  many  physicians  to  be  better  borne  and 
more  efficient  than  sodium  salicylate  prepared  from  synthetic 
acid;  according  to  Council  on  Ph.  &  C.  of  A.  M.  A.,  not 
superior  to  latter.  (See  also  Tablets  [Part  II].) 

0  Sodium  Sulphate,  Squibb  tin,  Ib.         ;  %  Ib. 

Sodii  Sulphas;  Glauber's  Salt.  Granular.  Na2SC>4.10H2O. 
Colorless,  transparent,  efflorescent  granules;  odorless;  of  bitter, 
saline  taste.  1  Gm.  dissolves  in  about  1  mil  (Cc.)  water; 
soluble  in  glycerin;  insoluble  in  alcohol.  Saline  Cathartic; 
more  unpleasant  than  magnesium  sulphate.  Average  Dose :  240 
grains  (15  Gm.).  Keep  well  stoppered;  very  efflorescent.  (See 
also  Reagents  [Part  IV].) 

Sodium  Sulphate  Dried,  Squibb      bottle,  Ib.        ;  %  Ib. 

NaoSC^.HoO.  The  crystalline  salt  deprived  of  water  of  crys- 
tallization. Therapeutically  twice  strength  of  crystals  or  granu- 
lar salt,  besides  having  the  advantage  of  being  more  uniform 
and  stable. 

Sodium  Sulphate  Anhydrous,  Reagent.       See     Reagents 
(Part  IV). 

Sodium  Sulphate,  Granular  Effervescent,  Squibb 

bottle,  Ib.          ;  4  ozs.,  per  doz. 

Contains  30  grains  sodium  sulphate  per  drachm.  Dose:  2  to 
8  drachms  (8  to  30  Gm.). 

©  Sodium  Sulphite  Dried,  Squibb      tin,  Ib.         ;  %  Ib. 

Sodii  Sulphis  Exsiccatus.  NaoSOs.  Granular  salt,  made 
from  high-quality  crystalline  sulphite  by  depriving  it  of  its 
crystal  water.  Readily  and  almost  perfectly  soluble  in  water; 
very  sparingly  soluble  in  alcohol.  Antiseptic,  Antizymotic; 
used  mainly  as  mouthwash  in  stomatitis,  in  1:16  solution. 
Average  Dose:  15  grains  (1  Gm.).  Incompatible  with  mineral 
acids.  Keep  well-stoppered,  in  cool  place. 

Sodium  Sulphocarbolate.        See  Sodium  Phenolsulphonate. 

Sodium  Tartrate,  Squibb  bottle,  %  Ib. 

White,  odorless,  almost  tasteless  crystals.  Freely  soluble  in 
water.  Succedaneum  for  Rochelle  and  Epsom  salts.  Dose: 
purgative,  4  to  8  drachms  (15  to  30  Gm.)  ;  diuretic  and  refrig- 
erant, 15  to  45  grains  (1  to  3  Gm.). 


SQUIBB'S  MATERIA  MEDICA       233 
0  Sodium  Thiosulphate,  Squibb  tin,  lb. 

Sodii  Thiosulphas.  N&^zOsSHzO.  More  commonly  but  in- 
correctly called  "Sodium  Hyposulphite."  Colorless,  granular 
salt;  cooling,  afterwards  bitter  taste;  efflorescent  in  warm  air, 
slightly  deliquescent  in  moist  air.  1  Gm.  dissolves  in  0.5  mil 
(Cc.)  water;  insoluble  in  alcohol.  Antiparasitic,  Antizymotic, 
Cathartic.  Used  largely  in  photography;  also  to  remove  iodine 
and  silver  nitrate  stains,  etc.  Average  Dose:  15  grains  (1  Gm.). 
Incompatible  with  acids,  iodine,  chlorine,  solutions  of  nitrates, 
silver  or  lead  salts.  Keep  can  well  closed,  in  cool  place.  (See 
also  Reagents  [Part  IV].) 

Sodium  and  Ammonium  Phosphate  Reagent.       See  Re- 
agents (Part  IV). 

Sodium  and  Potassium  Tart  rate.          See    Potassium    and 
Sodium  Tartrate. 

SOLANUM. 

Solanum,  N.  F.;  Horse-nettle  Berries.  Air-dried  ripe  fruit 
of  Solanum  carolinense  (Fam.  Solanacets).  Pepper-like  odor; 
bitter,  acrid  taste.  Used  as  Sedative,  in  convulsions  and  epi- 
lepsy. Average  Dose:  60  grains  (4  Gm.). 

Solargentum,  Squibb  bottle,  lb.        ;  %  lb.        ;  oz. 

Brownish-black,  lustrous,  odorless  granules,  containing  19  to 
23  percent,  silver  in  colloidal  form^  associated  with  an  organic 
protective  colloid.  Nonhygroscopic  under  ordinary  conditions. 
Freely  and  quickly  soluble  in  water;  neutral  and  perfectly  non- 
irritating  in  any  strength;  not  precipitated  from  its 
solutions  by  sodium  chloride,  and  does  not  coagulate 
albumin.  Non-irritant  Antiphlogistic  and  Germicide;  in 
gonorrhea,  and  in  inflammation  of  the  eyes,  ear,  nose  and 
throat.  Used  chiefly  in  I  to  25  percent,  or  stronger  solutions; 
also  in  bougies  and  suppositories.  [CAUTION. — There  are  a 
number  of  colloid  silver  preparations  on  the  market,  of  dif- 
fering descriptions.  It  is  therefore  necessary  to  specify 
"Solargentum,  Squibb"  when  this  product  is  desired.] 

©  SOLUTION  ACID  ARSENOUS. 

Liquor  Acidl  Arsenosi ;  frequently  erroneously  designated  as 
"Solution  Arsenic  Chloride."  Containing  1  percent,  arsenic 
trioxide  in  solution  with  dilute  hydrochloric  acid  and  water. 
Alterative,  Antiperiodic.  Average  Dose:  3  minims  (0.2  mil 
[Cc.]),  in  water.  Antidotes:  arsenic  antidote,  or  magnesia  in 
milk;  then  emetics.  Incompatible  with  iron  in  solution,  with 
vegetable  astringent  infusions,  tinctures-  or  decoctions. 


Since  we  make  only  one  quality  of  each  product,  that  best 
suited  to  the  purposes  intended,  the  specification  "Squibb's" 
is  not  open  to  various  interpretations,  but  has  a  plain,  positive 
meaning.  When  ordering  or  prescribing,  specify  SQUIBB'S. 


234       SQUIBB'S  MATERIA  MEDICA 

Solution  Acid  Carbolic  (Crude),  Squibb  quart 

2  percent,  solution  of  crude  90  percent,  carbolic  acid.  Used 
for  general  Disinfectant  and  household  purposes.  It  may,  with- 
out injury  or  staining,  be  freely  sprinkled  upon  bedding,  clothing, 
carpets,  floors,  furniture,  etc.,  or,  when  further  diluted,  may 
be  applied  to  the  body.  This  dilute  solution  may  be  safely 
entrusted  to  hands  unskilled .  in  the  use  of  powerful  medicinal 
agents,  and  yet  is  strong  enough  for  most  useful  purposes. 
Antidotes:  alcohol  or  whiskey  freely  at  once;  emetics  hypo- 
dermically;  raw  white  of  egg,  or  other  demulcents. 

®  Solution  Aluminum  Acetate,  Squibb      bottle,  pint, 

Liquor  Alumini  Acetatis,  N.  F.;  Burow's  Solution;  nol  Solu- 
tion Aluminum  Acetate,  N.  F.  III.  Made  by  interaction  of 
lead  acetate  and  aluminum  sulphate..  Contains  4.5  to  5.5  Gm. 
neutral  aluminum  acetate  in  100  mils  (Cc.).  External  Antiseptic 
and  Astringent;  used  diluted  with  1  to  3  parts  water. 

SOLUTION  ALUMINUM  ACETO-TARTRATE. 

Liquor  Alumini  Acetico-Tarlratis,  N.  F.  Contains  about  50 
percent,  aluminum  aceto-tartrat*  made  extemporaneously.  Ex- 
ternal Astringent,  Antiseptic. 

®  SOLUTION  ALUMINUM  SUBACETATE. 

Liquor  Alumini  Subacelalis,  N.  F.;  formerly  officially  known 
as  Solution  Aluminum  Acetate.  Contains  7.5  to  8  percent, 
basic  aluminum  acetate.  External  Antiseptic  and  Astringent; 
used  diluted  with  1  to  3  parts  water. 

®  SOLUTION  AMMONIUM  ACETATE. 

Liquor  Ammoni!  Acelatis;  Spirit  of  Mindererus.  7  percent. 
Clear,  colorless  liquid,  of  mildly  saline,  acidulous  taste.  Di- 
aphoretic, Diuretic.  Average  Dose:  4  fluidrachms  (15  mils 
[Cc.]).  Should  not  be  dispensed  unless  recently  prepared. 

SOLUTION  AMMONIUM  CITRATE. 

Liquor  Ammonii  Citratis,  N.  F.  Each  fluidounce  represents 
about  72  grains  ammonium  citrate.  Diaphoretic,  Refrigerant. 
Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

Solution  Antiseptic,  Squibb  bottle,  pint 

We  have  not  adopted  the  N.  F.  IV  formula  for  Liquor  Anli- 
seplicus,  which  yields  an  unsightly  product,  but  have  adhered 
to  U.  S.  P.  VHIth  Rev.  formula.  Each  1000  mils  (Cc.) 
contains  20  Gm.  boric  acid,  1  Gm.  benzoic  acid,  1  Gm.  thymol, 
0.25  mil  eucalyptol,  0.5  mil  oil  peppermint,  0.25  mil  methyl 
salicylate,  0.1  mil  oil  thyme,  with  alcohol  and  water.  Used 
diluted  with  1  to  4  parts  water.  Average  Dose:  1  fiuidrachm 
(4  mils). 


SQUIBB'S  MATERIA  MEDICA       235 

Solution  Antiseptic,  Alkaline,  Squibb  bottle,  pint 
Liquor  Antiseplicus  Alfyalinus,  N.  F.  1000  mils  (Cc.)  con- 
tain 32  Gm.  each  potassium  bicarbonate  and  sodium  borate,  8 
Cm.  sodium  benzoate,  and  a  little  eucalyptol,  oil  peppermint, 
methyl  salicylate  and  thymol,  with  alcohol,  glycerin  and  water. 
Employed  externally  in  nose  and  throat  affections;  as  a  mouth 
wash;  in  burns,  insect  bites,  leucorrhea,  etc.;  internally  as  Anti- 
fermentative.  Used  diluted  with  1  to  4  parts  water.  Dose: 
1  to  2  fluidrachms  (4  to  8  mils  [Cc.]). 

SOLUTION  ARSENIC,  CLEMENS*. 

Liquor  Arsenicalis  Clemens,  N.  F.;  Solution  Potassium  Arsen- 
ate  and  Bromide;  Solution  Arsenic  Bromide.  Contains  equiva- 
lent of  1  percent,  arsenic  trioxide  as  arsenate  and  bromide  of 
potassium.  Alterative;  also  used  in  diabetes.  Average  Dose: 
3  minims  (0.2  mil  [Cc.]). 

SOLUTION   ARSENIC   BROMIDE.     See  Solution  Arsenic,   Clemens'. 
SOLUTION  ARSENIC  CHLORIDE.    See  Solution  Acid  Arsenous. 

0  Solution  Arsenic  and  Mercury  Iodide,  Squibb 

bottle,  pint,          ;  ]/^  pint,          ;  oz. 

Liquor  Arseni  et  Hydrargyri  lodidi;  Donovan's  Solution. 
About  I  percent.. each  arsenous  iodide  and  red  mercuric  iodide, 
in  aqueous  solution.  Alterative,  Antiluetic.  Average  Dose : 
l*/2  minims  (0.1  mil  [Cc.]).  Incompatible  with  alkalies  and 
solutions  alkaloidal  salts.  Antidotes:  arsenic  antidote,  or  milk 
and  magnesia;  then  emetics. 

SOLUTION  BISMUTH. 

Liquor  Bismuthi,  N.  F. ;  Liquid  Bismuth.  Each  fluidrachm 
contains  2  gr.  bismuth  and  sodium  tartrate  with  alcohol,  glycerin 
and  water.  Used  as  Gastric  Sedative.  Average  Dose:  1 
fluidrachm  (4  mils  [Cc.]). 

Solution  Bismuth,  Concentrated.    See  Glycerite  Bismuth. 
SOLUTION  BROMINE.  " 

Liquor  Bromi,  N.  F.;    Smith's  Solution  Bromine.     25  percent. 

Br.  with  5  percent,  potassium  bromide.     Antiseptic.     Antidotes: 

ammonia   by   inhalation ;    sodium   carbonate   in   dilute   solution ; 

albumen. 

Solution  Bromine  for  Urea  Estimation.    See    Urea    Ap- 
paratus. 

SOLUTION  CALCIUM  HYDROXIDE. 

Liquor  Calcis;  Lime  Water.  Contains  not  less  than  0.14  per- 
cent. Ca(OH)o.  Antacid.  Dose:  4  fluidrachms  (15  mils 
[Cc.]).  

The  founder  of  the  House  of  Squibb,  Dr.  Edward  R.  Squibb, 
not  only  had  high  ideals,  but  lived  and  labored  for  them;  and, 
in  the  words  of  William  Miller  Bartlett,  "the  House  of  Squibb 
stands  today  as  a  living  monument  to  the  honor,  integrity,  zeal 
and  devotion  of  its  founder." 


236       SQUIBB'S  MATERIA  MEDICA 

SOLUTION  CARMINE. 

Liquor  Carmini,  N.  F.  Each  100  mils  (Cc.)  contains  6.5  Gm. 
carmine,  36.5  mils  each  ammonia  water  and  glycerin,  and 
water.  Coloring. 

SOLUTION,    CHANNING'S.      See    Solution    Mercury    and    Potas- 
sium  Iodide. 

SOLUTION  CHLORINE  COMPOUND. 

Liquor  Chlori  Composilus,  N.  F.;  Chlorine  Water.  0.35  Gm. 
chlorine  in  100  mils  (Cc.).  Yellow  liquid;  strong  odor  and 
taste  of  chlorine.  Disinfectant,  Antizymotic;  Reagent.  Aver- 
age Dose:  I  fluidrachm  (4  mils),  well  diluted.  Very  unstable; 
should  not  be  dispensed  unless  recently  made. 

SOLUTION,  CLEMENS^    See  Solution  Arsenic,  Clemens'. 

SOLUTION  COAL  TAR. 

Liquor  Picis  Carbonis,  N.  F.  Each  100  mils  (Cc.)  contains 
20  Gm.  coal  tar  dissolved  by  aid  of  10  Gm.  quillaja.  Stimu- 
lating Antiparasitic  and  Antipruritic  Dermic. 

0  Solution  Cresol  Compound,  Squibb       bottle,  pint 

Liquor  Cresolis  Compositus.  50  percent,  pure  cresol,  held  in 
solution  by  soap  produced  from'  linseed  oil  and  sodium  hy- 
droxide. Light-amber  liquid;  phenol-like  odor.  Soluble  in 
warm  water  in  all  proportions.  Darkens  with  age,  but  this 
does  not  affect  its  antibacterial  action.  Superior  succedaneum 
for  carbolic  acid  (phenol),  having  carbolic  acid  coefficient  of 
about  3,  hence  three  times  as  powerful  as  latter.  Powerful. 
Antiseptic,  Disinfectant,  Deodorant  and  Parasiticide.  Does 
not  precipitate  albumen,  attack  instruments,  nor  stain  linen. 
Used  in  1  to  3  percent,  solution,  best  made  with  warm  water. 

Solution,    Dobell's.        See  Solution  Sodium  Berate  Compound. 

Solution,  Donovan's.    See     Solution     Arsenic     and     Mercury 
Iodide. 

Solution,  Fehling's.    See   under   Fehling's   Test   Solution    Ele- 
ments. 

®  SOLUTION  FORMALDEHYDE. 

Liquor  FormalJehydi ;  Formalin;  Formol.  Aqueous  solution 
containing  not  less  than  37  percent.  CHi>O.  Clear,  colorless 
liquid;  pungent  odor;  caustic  taste;  irritating  vapor;  sp.  gr. 
1.075  to  1.078;  miscible  with  water  or  alcohol.  General  Disin- 
fectant, Deodorant,  Antihydrotic ;  hardener  of  microscopical 
specimens.  Used  in  J/2  to  2  percent,  solution  medicinally;  in 
weaker  solutions  for  hygienic  purposes.  Incompatible  with  al- 
kalies, ammonia,  and  oxidizing  agents.  Antidotes:  solution  am- 
monium acetate;  ammonia  by  inhalation. 

Solution    Fowler's.     See  Solution  Potassium  Arsenite. 


SQUIBB'S  MATERIA  MEDICA        237 

Solution  Glycerophosphates  Compound,  Squibb 

(No  Sugar)  bottle,  pint, 

Each  fluidounce  contains  8  grains  calcium  glycerophosphate,  16 
grains  sodium  glycerophosphate  (75%);  P/2  grains  iron  gly- 
cerophosphate, 1  grain  manganese  glycerophosphate,  J/2  grain 
quinine  glycerophosphate,  and  i/16  grain  strychnine  glycero- 
phosphate. Employed  as  Nerve  tonic,  where  the  correspond- 
ing elixir  glycerophosphates  compound  is  considered  ob- 
jectionable on  account  of  the  sugar.  Ordinary  Dose:  1  fluid 
drachm  (4  mils  [Cc.]),  in  water,  before  meals.  (See  also 
Elixir;  Tablets  [Part  II].) 

Solution  Gold  and  Arsenic  Bromide,  Squibb 

g.  s.  bottle,  pint,          ;  J/j  pint,          ;  oz. 

Liquor  Auri  el  Arseni  Bromidi,  N.  F.  III.  Owing  to  the  im- 
possibility of  procuring  bromauric  acid,  called  for  in  present 
N.  F.,  these  laboratories  continue  to  supply  the  N.  F.  Ill  pro- 
duct. Each  10  minims  contains  i/32  grain  gold  tribromide  and 
1/40  grain  arsenous  acid.  Used  as  Alterative,  Antidiabetic, 
Antiepileptic.  Average  Dose:  3  minims  (0.2  mil  [Cc.]). 

SOLUTION  GUTTA  PERCHA. 

Liquor  Guiles  Perches,  N.  F. ;  Traumaticin.  15  Gm.  gutta 
percha  dissolved  in  100  mils  (Cc.)  chloroform.  Protective, 
like  collodion. 

SOLUTION,    HALL'S.     See    Solution    Strychnine   Acetate. 

SOLUTION  HYDRASTINE  COMPOUND. 

Liquor  Hydrastincs  Compositus,  N.  F.;  Colorless  Hydrastine 
Solution.  Each  fluidounce  contains  about  !3/g  grains  each 
hydrastine  hydrochloride,  aluminum  chloride,  calcium  chloride, 
and  magnesium  chloride,  */o  grain  potassium  chloride,  240 
minims  glycerin,  and  water.  Antiseptic  Astringent  externally; 
Tonic  and  Hemostatic  internally.  Average  Dose:  1  fluidrachm 
(4  mils  [Cc.]). 

®  Solution  Hydrogen  Peroxide,  Squibb 

bottle,  Ib.          ;  1/2  Ib.         ;  |4  Ib. 

Liquor  HyJrogenii  Dioxidi ;  Solution  Hydrogen  Dioxide.  3 
percent.  H2C>2,  equivalent  to  10  volumes  available  oxygen. 
Made  by  an  improved  process  which  insures  high  purity  and 
excellent  keeping  properties.  Free  from  acetanilid  and  alcohol. 
A  harmless,  non-staining  Antiseptic,  Disinfectant  and  Deodor- 
izer; on  cuts,  wounds,  etc.;  as  an  antiseptic  mouth  wash;  de- 
odorizer of  the  body,  utensils,  etc.  Used  pure  or  diluted  with 
1  to  3  parts  water.  Used  also  as  Reagent.  Average  Dose :  1 
fluidrachm  (4  mils  [Cc.]).  Keep  in  cool  place  and  quiet; 
occasionally  remove  the  cork. 

The  Squibb  Ideals  have  taken  concrete  form  in  the  Squibb 
Products;  these  are  universally  recognized  as  standards  of 
uniform  Purity  and  Efficacy,  that  is,  general  Excellence  and 
Reliability.  Specify  SQUIBB'S  when  prescribing  or  ordering.. 


238       SQUIBB'S  MATERIA  MEDICA 

SOLUTION  HYPOPHOSPHITES. 

Liquor  Hypophosphilum,  N.  F.  Each  fluidounce  contains 
about  16',  i  grains  calcium  hypophosphite,  9  grains  sodium 
hypophosphite,  8Vs  grains  potassium  hypophosphite,  in  water; 
unsweetened.  Alterative  Tonic.  Average  Dose:  1  fluidrachm 
(4  mils  [Cc.]).  (See  also  Syrup.) 

Solution  Hypophosphites  Compound,  Squibb 

(No  Sugar)  pint, 

Liquor  Hypophosphilum  Composilus,  N.  F.  Each  fluidounce 
contains  about  4  grains  each  calcium  and  potassium  hypophos- 
phites,  1  grain  each  sodium,  quinine  and  manganese  hypophos- 
phites,  2  grains  ferric  hypophosphite,  and  */32  grain  strychnine 
hypophosphite.  Used  in  place  of  Syrup  Hypophosphites  Com- 
pound where  sugar  is  objectionable.  Average  Dose:  1  fluid 
drachm  (4  mils  [Cc.]),  after  meals. 

0  Solution  Hypophysis,  Squibb 

box  of  6X1   Cc.  ampuls, 
box  of  6X0.5   Cc.   ampuls, 

Liquor  Hypophysis;  Solution  of  Pituitary  Body.  Prepared 
under  aseptic  conditions  from  posterior  lobes  of  fresh  pituitary 
gland  from  cattle,  and  carefully  standardized  and  sterilized. 
Stimulant  and  Constrictor  of  unstriped  muscle,  especially  that 
of  the  uterus  and  blood  vessels;  used  in  second  stage  of  labor, 
uterine  atony  with  post-partum  hemorrhage  and  other  forms 
of  uterine  bleeding,  shock  and  other  conditions  of  low  blood 
pressure,  certain  cases  of  pulmonary  hemorrhage,  post-operative 
intestinal  paresis,  etc.  Average  Dose:  16  minims  (1  mil  [Cc.]) 
hypodermically,  repeated  in  30  to  60  minutes  if  necessary. 

SOLUTION  IODINE  COMPOUND. 

Liquor  lodi  Composilus;  Lugol's  Solution.  Aqueous  liquid 
containing  about  5  percent,  iodine  and  10  percent,  potassium 
iodide.  Alterative.  Average  Dose:  3  minims  (0.2  mil  [Cc.]), 
diluted. 

SOLUTION  IODINE  PHENOLATED. 

Liquor  lodi  Phenolalus,  N.  F.;  Boulton's  Solution.  Each  100 
mils  (Cc.)  contains  1 .5  mils  compound  solution  iodine,  0.6  mil 
liquefied  carbolic  acid,  16.5  mils  glycerin,  water  q.  s.  Antiseptic. 

SOLUTION  IRON  ACETATE. 

Liquor  Ferri  Acetalis,  N.  F.  31  percent,  anhydrous  ferric 
acetate,  equivalent  to  7.5  percent.  Fe.  Hematinic,  Hemostatic. 
Average  Dose:  5  minims  (0.3  mil  [Cc.]). 

Solution   Iron   Albuminate,   Squibb  pint, 

Of  same  Iron  Albuminate  strength  as  the  Liquor  Ferri  Albu- 
minati,  N.  F.,  but  made  by  a  process  yielding  a  better  article. 
Each  fluidounce  contains  2.4  grains  metallic  iron  as  albuminate. 
Hematinic.'  Average  Dose:  2  fluidrachms  (8  mils  [Cc.]). 


SQUIBB'S  MATERIA  MEDICA        239 

Solution  Iron  Chloride,  Squibb  g.  s.  bottle,  pint 

Liquor  Ferri  Chloridi.  About  29  percent,  anhydrous  ferric 
chloride  (equivalent  to  10  percent,  iron).  Reddish-brown 
liquid;  acid,  strongly  styptic  taste;  acid  reaction.  Sp.  gr. 
1 .29  to  1 .32.  Astringent,  Styptic,  Hematinic ;  but  used  mainly 
pharmaceutically.  Average  Dose:  l'/2  minims  (0.1  mil  [Cc.]), 
well  diluted. 

SOLUTION  IRON  CITRATE. 

Liquor  Ferri  Citratis,  N.  F.  Aqueous  solution  containing  ferric 
citrate  corresponding  to  7.25  percent.  Fe.  Hematinic.  Aver= 
age  Dose:  10  minims  (0.65  mil  [Cc.]). 

SOLUTION   IRON  HYPOPHOSPHITE. 

Liquor  Ferri  Hypophosphilis,  N.  F.  Each  fluidrachm  contains 
about  10  grains  iron  hypophosphite,  in  glycerin  and  water. 
Hematinic.  Average  Dose:  15  minims  (I  mil  [Cc.]). 

Solution  Iron  Iodide,  Squibb 

1  -oz.  ampuls,  2  in  box,  per  box, 

Designed  for  convenient  preparation  of  Syrup  Iron  Iodide. 
Contains  about  81  Gm.  iron  iodide  (ferrous)  in  100  mils  (Cc.). 
Sp.  gr.  about  1.73.  One  volume  with  11  volumes  syrup  makes 
syrup  iron  iodide  of  official  strength. 

Solution  Iron  Nitrate,  Squibb  Ib. 

Liquor  Ferri  Nitralis,  N.  F.  Contains  about  6  percent,  an- 
hydrous salt,  or  about  1 .3  percent,  metallic  iron.  Clear,  red- 
dish liquid;  sp.  gr.  about  1,060.  Astringent,  Styptic,  Hematinic. 
Average  Dose:  5  minims  (0.3  mil  [Cc.]). 

Solution  Iron  Oxychloride,  Squibb  pint 

Liquor  Ferri  OxychloriJi,  N.  F.  Contains  ferric  oxychloride 
corresponding  to  about  3  percent,  metallic  iron,  dissolved  in 
mixture  of  glycerin  and  water.  Hematinic,  Astringent,  and  Ar- 
senic Antidote,  but  used  mainly  for  preparing  Solution  Iron 
Albuminate.  Solution  Iron  Peptonate,  and  Solution  Iron  Pep- 
tonate  with  Manganese.  Average  Dose :  30  minims  (2  mils 
[Cc.]). 

SOLUTION  IRON  OXYSULPHATE. 

Liquor  Ferri  Oxysulphaiis,  N.  F.  100  mils  (Cc.)  contain 
product  of  interaction  of  16.5  Gm.  each  ferrous  sulphate  and 
nitric  acid.  Astringent. 

Solution  Iron  Peptonate,  Squibb  pint 

Liquor  Ferri  Peplonati,  N.  F.  Each  fluidounce  contains  about 
2J/4  grains  metallic  iron  as  peptonate.  Hematinic.  Average 
Dose:  2  fluidrachms  (8  mils  [Cc.]). 


The  Squibb  Label  on  a  package  is  a  positive  guaranty  for  the 
uniform  Purity  and  Reliability  of  the  product.  We  make  only 
ONE  quality:  the  SQUIBB  quality;  and  our  prices  are  as  low 
as  they  can  be  made  for  that  quality.  Specify  SQUIBB'S. 


240       SQUIBB'S  MATERIA  MEDICA 

Solution  Iron  Peptonate  and  Manganese,  Squibb 

pint, 

Liquor  Ferri  Peptonall  et  Mangani,  N.  F.  Each  fluidounce 
contains  about  2'/4  grains  metallic  iron  as  peptonate  and  '3 
grain  metallic  manganese  as  citrate.  Hematinic.  Average  Dose: 
2  fluidrachms  (8  mils  [Cc.]),  after  meals. 

Solution  Iron  Peptonate  with  Manganese  and  Arsenic, 
Squibb  pint, 

Preceding  article  with  addition  of  1/so  grain  arsenous  acid  per 
fluidounce.  Hematinic,  Alterative.  Ordinary  Dose:  2  fluid 
drachms  (8  mils  [Cc.]). 

SOLUTION  IRON  PROTOCHLORIDE. 

Liquor  Ferri  Protochloridi,  N.  F.;  Solution  Ferrous  Chloride. 
About  30  percent.  FeClo.  Hemalinic,  Astringent;  also  used 
pharmaceutically.  Average  Dose:  10  minims  (0.65  mil.  [Cc.]). 

SOLUTION  IRON  SALICYLATE. 

Liquor  Ferri  Salicylalis,  N.  F.  Each  100  mils  (Cc.)  contains 
product  of  interaction  of  12.5  Gm.  sodium  salicylate  and  12.5 
mils  tincture  iron  citro-chloride,  17.5  mils  glycerin,  and  0.2 
mil  methyl  salicylate  as  flavor.  Used  as  Hematinic  Anti- 
rheumatic.  Average  Dose:  2  fluidrachms  (8  mils  [Cc.]). 

Solution  Iron  Subsulphate,  Squibb  bottle,  lb.  J4  lb. 
Liquor  Ferri  Subsulphatis ;  Monsel's  Solution.  13  to  14  per- 
cent, iron.  Dark,  reddish-brown  liquid,  of  strong,  acid,  styptic 
taste;  sp.  gr.  about  1.548.  Miscible  in  all  proportions  with 
water  or  alcohol.  Liable  to  crystallize,  and  then  becomes  a 
dirty  whitish,  semi-solid  mass.  This  does  not  injure  the  prep- 
aration in  the  least,  and  all  that  is  needed  to  restore  it  to  its 
original  condition  is  to  set  it  in  a  warm  place  until  it  melts. 
But  even  the  unattractive-looking  crystalline  mass  will  be  found 
to  act  as  a  styptic  as  effectually  as  the  clear  solution.  Styptic, 
Astringent,  pure  or  in  strong  solution;  rarely  used  internally. 
Average  Dose:  3  minims  (0.2  mil  [Cc.]), 

Solution    Iron    Tersulphate,    Squibb  bottle,  lb. 

Liquor  Ferri  Tersulphaiis ;  36  percent,  normal  ferric  sulphate; 
or  10  percent,  metallic  iron.  Free  from  nitric  acid  and  ferrous 
salt.  Dark,  reddish-brown,  nearly  odorless,  acid  liquid;  strong- 
ly styptic  taste;  sp.  gr.  about  1 .432.  Miscible  with  water  or 
alcohol.  Astringent,  Styptic,  like  subsulphate  solution,  but  less 
powerful  and  more  irritating. 

SOLUTION  IRON  AND  AMMONIUM  ACETATE. 

Liquor  Ferri  el  Ammonii  Aceiatis;  Basham's  Mixture.  Made 
from  tincture  ferric  chloride,  acetic  acid,  solution  ammonium 
acetate,  aromatic  elixir,  glycerin  and  water.  Should  be  freshly 
made  as  wanted;  spoils  readily.  Hematinic.  Average  Dose: 
4  fluidrachms  (15  mils  [Cc.]). 


SQUIBB'S  MATERIA  MEDICA       241 

Solution,   Labarraque's.        See  Solution  Soda  Chlorinated. 
©  Solution  Lead  Subacetate,  Squibb  Ib. 

Liquor  Plumbi  Subacetalis ;  Goulard's  Extract.  25  percent, 
(equal  to  18  percent.  Pb).  Clear,  colorless,  odorless  liquid, 
of  sweetish,  astringent  taste.  Sp.  gr.  about  1 .245.  Astringent 
and  Antiseptic,  but  used  chiefly  pharmaceutically  and  as 
Reagent. 

SOLUTION  LEAD  SUBACETATE  DILUTED. 

Liquor  Plumbi  Subacetatis  Dilulus;  Lead  Water;  Goulard's 
Water.  1  percent,  lead  subacetate.  External  Astringent  and 
Antiphlogistic,  undiluted. 

SOLUTION,  LUGOL'S.     See  Solution  Iodine  Compound. 

©  SOLUTION  MAGNESIUM  CITRATE. 

Liquor  Magnesii  Citratis.  100  mils  (Cc.)  contain  magnesium 
citrate  corresponding  to  not  less  than  1 .5  Gm.  magnesium  oxide. 
Mild,  pleasant  Saline  Laxative.  Average  Dose:  12  fluidounces 
(350  mils  [Cc.]). 

SOLUTION  MAGNESIUM  SULPHATE  EFFERVESCENT. 

Liquor  Magnesii  Sulphalis  Effervescent,  N.  F.  Each  12  fluid- 
ounces  contains  385  grains  magnesium  sulphate,  with  syrup  citric 
acid  as  flavor.  Saline  Laxative.  Average  Dose:  12  fluid- 
ounces  (350  mils  [Cc.]). 

SOLUTION  MERCURY  NITRATE. 

Liquor  Hydrarstyri  Nitralis,  N.  F.  About  60  percent,  mercuric 
nitrate,  1  1  percent,  free  nitric  acid.  Clear,  nearly  colorless 
liquid;  faint  odor  of  nitric  acid;  strongly  acid  reaction;  sp.  gr. 
about  2.086.  Caustic.  Antidotes:  magnesia,  chalk,  or  soap  and 
water;  emetics;  raw  eggs  and  demulcents. 

SOLUTION  MERCURY  AND  POTASSIUM  IODIDE. 

Liquor  Hydrargyri  el  Potassii  lodidi,  N.  F. ;  Channing's  Solu- 
tion; Solution  Potassium  lodohydrargyrate.  1  percent,  red 
iodide  of  mercury,  with  0.8  percent,  potassium  iodide.  Altera- 
tive, Antisyphilitic.  Average  Dose:  3  minims  (0.2  mil  [Cc.]), 
after  meals,  diluted.  Incompatible  with  alkaloidal  salts  or 
alkalies. 

Solution,  MonsePs.        See  Solution  Iron  Subsulphate. 
SOLUTION    NITROGLYCERIN.      See    Spirit    Glyceryl    Trinitrate. 

This  house  supplies  only  one  quality  of  each  product:  that  best 
suited  to  the  purposes  intended.  The  specification  "Squibb's" 
is  not  open  to  various  interpretations;  it  has  a  plain,  posi- 
tive meaning.  Therefore,  when  prescribing,  specify  SQUIBB'S. 


242        SQUIBB'S  MATERIA  MEDICA 

SOLUTION  PANCREATIN. 

Liquor  Pancrealini,  N.  F.  Each  fluidounce  contains  8|/g  grains 
pancreatin,  and  about  23  grains  sodium  bicarbonate,  with 
glycerin,  compound  spirit  cardamom,  etc.  Digestive,  in  intes- 
tinal indigestion.  Average  Dose:  I  fluidrachm  (4  mils  [Cc.]). 

SOLUTION,  PEAKSON'S.     See  Solution  Sodium  Arsenate,  Pearson's. 

SOLUTION  PEPSIN. 

Liquor  Pepsini,  N.  F.  Each  fluidounce  contains  2  grains  pep- 
sin, 4.8  minims  hydrochloric  acid,  glycerin  and  water. 
Proteolytic.  Average  Dose:  2  fluidrachms  (8  mils  [Cc.]). 

SOLUTION  PEPSIN  ANTISEPTIC. 

Liquor  Pepsini  Anliseplicus,  N.  F.  Each  100  mils  (Cc.)  con- 
tains 5  Gm.  pepsin,  0.05  mil  each  menthol,  eucalyptol  and 
glycerin,  water.  Antiseptic  Solvent  of  false  membrane,  Stim- 
ulant of  sluggish  ulcers,  etc. 

SOLUTION  PEPSIN  AROMATIC. 

Liquor  Pepsini  Aromalicus,  N.  F.  Each  fluidounce  contains 
about  8J/g  grains  pepsin,  4.8  minims  hydrochloric  acid,  with  oils 
cinnamon,  pimenta  and  cloves  as  flavor,  alcohol,  glycerin,  water. 
Aromatic  Digestive ;  Vehicle.  Average  Dose :  2  fluidrachms 
(8  mils  [Cc.]). 

SOLUTION  PHOSPHATES  ACID. 

Liquor  Phosphatum  AciJus,  N.  F. ;  Solution  Acid  Phosphates. 
Acid  solution  of  calcium  and  magnesium  phosphates,  extem- 
poraneously made.  Bone  Nutrient,  Tonic.  Average  Dose :  1 
fluidrachm  (4  mils  [Cc.]). 

SOLUTION  PHOSPHATES  COMPOUND. 

Liquor  Phosphalum  Compositus,  N.  F.  Flavored,  sweetened 
solution  of  phosphates  of  calcium,  ammonium,  potassium, 
sodium  and  iron;  16J/4  grains  ferric  phosphate  per  fl.  oz.  Anti- 
cachectic,  Bone  Nutrient,  Hematinic.  Ordinary  Dose:  1  fluid 
drachm  (4  mils  [Cc.]). 

SOLUTION  PHOSPHORUS. 

Liquor  Phosphori,  N.  F.;  Thompson's  Solution  Phosphorus. 
!/24  grain  phosphorus  in  1  fluidrachm,  with  alcohol,  spirit  pep- 
permint and  glycerin.  Stimulant  of  bone  formation,  in  rickets, 
etc.  Average  Dose:  10  minims  (0.65  mil  [Cc.]).  Antidotes: 
potassium  permanganate;  charcoal,  or  lime  water;  emetics. 

Solution  Potassa.     See  Solution  Potassium  Hydroxide. 

SOLUTION  POTASSA  CHLORINATED. 

Liquor  Polasste  Chlorinates,  N.  F.;  Javelle  Water.  Assays 
about  2  percent,  available  chlorine.  Disinfectant,  Antizymotic; 
used  mostly  externally  (ulcers,  aphthae,  tonsillitis,  etc., 
in  1:8  dilution).  Dose:  5  to  10  minims  (0.3  to  0.65  Cc.) 
well  diluted.  Antidotes:  white  of  egg,  then  emetics;  ammonia 
water. 


SQUIBB'S  MATERIA  MEDICA       243 

SOLUTION    POTASSIUM   ARSENATE   AND    BROMIDE.    See   Solution 
Arsenic,   Clemens'. 

0  Solution  Potassium  Arsenite,  Squibb 

bottle,  pint         ;   oz. 

Liquor  Potassti  Arsenitts;  Fowler's  Solution  (Arsenical).  Con- 
tains potassium  arsenite  equivalent  to  about  1  percent,  arsenic 
trioxide,  with  compound  tincture  lavender  as  flavor.  Altera- 
tive, Antiperiodic.  Average  Dose:  3  minims  (0.2  mil  [Cc.]). 
Antidotes:  arsenic  antidote,  or  milk  and  magnesia;  emetics. 

SOLUTION  POTASSIUM  CITRATE. 

Liquor  Potassii  Cilralis.  Aqueous  solution  containing  8  per- 
cent, anhydrous  potassium  citrate.  Clear,  colorless,  odorless 
liquid;  mildly  saline  .taste.  Systemic  Alkali,  Diuretic. 
Average  Dose:  4  fluidrachms  (15  mils  [Cc.]).  Should  not  be 
dispensed  unless  recently  made. 

©  Solution  Potassium  Hydroxide,  Squibb 

rubber-stopper  bottle,  pint 

Liquor  Polassii  Hydroxidi ;  Solution  Potassa.  Carefully  made 
from  an  exceptionally  pure  potassium  hydroxide,  of  which  it 
contains  from  4.5  to  5  percent.  Clear,  colorless  liquid;  acrid, 
caustic  taste,  strongly  alkaline  reaction;  sp.  gr.  about  1.046. 
Systemic  Antacid.  Average  Dose:  15  minims  (1  mil  [Cc.]), 
diluted.  Antidotes:  lemon  juice  or  vinegar;  milk  and  eggs. 

SOLUTION    POTASSIUM    IODOHYDRARGYRATE.     See    Solution    Mer- 
cury and  Potassium   Iodide. 

SOLUTION  SALT,  PHYSIOLOGICAL.     See  Solution  Sodium  Chloride. 

Solution  Soda.     See  Solution  Sodium  Hydroxide. 

Solution  Soda  for  Urea  Estimation.      See  Urea  Apparatus. 

0  Solution  Soda  Chlorinated,  Squibb 

rubber-stopper  bottle,  per  doz.  pints 

Liquor  Sods  Chlorinaia  (Chlorals),  U.  S.  P.  1870;  Labar- 
raque's  Solution.  A  more  satisfactory  product  than  present 
official  formula  yields.  Contains  2.5  percent,  available  chlorine. 
Pale-greenish  liquid;  faint  chlorine  odor;  disagreeable  taste; 
sp.  gr.  about  1.050.  Disinfectant,  Antizymotic.  Ordinary 
Dose:  15  minims  (1  mil  [Cc.]),  diluted.  Externally,  diluted 
with  2  to  4  parts  water.  Antidotes :  ammonia  water,  then 
emetics;  milk  and  eggs. 


The  prices  of  the  Squibb  Products  are  in  all  instances  as  low  as 
the  quality  and  quantity  of  ingredients  and  the  expense  of  man- 
ufacture allow.  They  include  containers,  packing  and  boxing.  When 
ordering  or  prescribing  medicinal  products,  specify  SQUIBB'S. 


244       SQUIBB'S  MATERIA  MEDICA 

SOLUTION  SODA  AND  MINT. 

Liquor  Soda  el  Menlha,  N.  F.;  Mixture  Soda  and  Spearmint. 
Each  fluidounce  represents  22J/2  grains  sodium  bicarbonate  and 
5  minims  aromatic  spirit  ammonia,  with  spearmint  water. 
Antacid,  Carminative.  Average  Dose:  2  fluidrachms  (8  mils 
[Cc.]).  Incompatible  with  alkaloidal  salts  or  acids. 

SOLUTION  SODIUM  ARSENATE. 

Liquor  Sodii  Arsenatis  Pearson,  N.  F.;  Pearson's  Solution. 
O.I  percent,  exsiccated  sodium  arsenate.  Not  to  be  confounded 
with  Solution  Sodium  Arsenate  U.  S.  P.  VHIth.  Rev.,  which 
is  ten  times  stronger.  Alterative,  Antiperiodic ;  in  chronic  skin 
diseases,  chorea,  neuralgia,  etc.  Average  Dose :  30  minims  (2 
mils  [Cc.]). 

Solution  Sodium  Borate  Compound,  Squibb         pint 
Liquor   Sodii    Boralis    Compositus,    N.    F.;    Dobell's   Solution. 
About  1 .5  percent,  each  sodium  borate  and  sodium  bicarbonate, 
0.3  percent,  carbolic  acid,  glycerin  and  water.     Alkaline  Anti- 
septic;   in  nasal  and  laryngeal  affections  chiefly. 

SOLUTION  SODIUM  CHLORIDE  PHYSIOLOGICAL. 

Liquor  Sodii  Chloridi  Physiologicus ;  Normal  Salt  Solution. 
Sterilized.  0.85  percent.  For  venous  transfusion,  hypodermo- 
clysis,  etc. 

SOLUTION  SODIUM  CITRATE. 

Liquor  Sodii  Citratis,  N.  F.;  River's  Potion.  Each  100  mils 
(Cc.)  contains  product  resulting  from  action  of  2  Gm.  citric 
acid  on  2.5  Gm.  sodium  bicarbonate.  Systemic  Alkali, 
Diuretic.  Average  Dose :  2  fluidrachms  (8  Cc.) .  Should 
be  freshly  made  as  ordered. 

SOLUTION  SODIUM  CITRO-TARTRATE  EFFERVESCENT. 

Liquor  Sodii  Cilro-Tartralis  Effervescent,  N.  F.  Each  350 
mils  (12  fl.  oz.)  contains  product  of  interaction  of  sodium 
bicarbonate  26  Gm.,  tartaric  acid  24  Gm.,  citric  acid  2  Gm., 
with  syrup  citric  acid  50  mils  (Cc.)  and  water.  Refrigerant, 
Laxative.  Average  Dose:  12  fluidounces  (350  mils). 

Solution  Sodium  Glycerophosphate,  Squibb 

bottle,  Ib.          ;  J4  Ib.          ;  oz. 

Liquor  Sodii  Clycerophosphaiis.  Aqueous  solution  containing  50 
percent,  anhydrous  Na2C3H7PO(j.  Clear,  colorless  or  yellow- 
ish, syrupy  liquid.  Used  as  Nerve  Tonic.  Average 
Dose:  6  minims  (0.4  mil  [Cc.]).  (See  also  Sodium  Glycero- 
phosphate.) 

0  Solution  Sodium  Hydroxide,  Squibb 

rubber-stopper  bottle,  pint, 

Liquor  Sodii  Hydroxidi ;  Solution  Soda.  Contains  4.5  to  5 
percent,  sodium  hydroxide;  sp.  gr.  about  1.056.  Very  acrid, 
caustic  taste.  Systemic  Antacid.  Average  Dose:  15  minims 
(1  mil  [Cc.]),  diluted.  Antidotes:  lemon  juice  or  vinegar; 
milk  and  eggs. 


SQUIBB'S  MATERIA  MEDICA       245 

Solution  Sodium  Phosphate  Compound,  Squibb       pint 
Liquor  Sodii  Phosphatis  Compositus,  N.  F.;   Liquefied  Sodium 
Phosphate.     Made  from  sodium  phosphate,  citric  acid,  glycerin 
and  water.      1    mil    (Cc.)    represents    1    Cm.  sodium  phosphate. 
Laxative.     Average  Dose:  2  fiuidrachms  (8  mils). 

SOLUTION  STRYCHNINE  ACETATE. 

Liquor  Strychnines  Acetalis,  N.  F.;  Hall's  Solution  Strychnine. 
]/Q  grain  strychnine  acetate  in  1  fluidrachm,  with  alcohol,  com- 
pound tincture  cardamom  and  water.  Nervine,  Stomachic. 
Average  Dose:  10  minims  (0.65  mil  [Cc.]).  Antidotes:  tannin, 
then  emetics;  chloral  hydrate  with  bromides  per  rectum;  chloro- 
form by  inhalation  if  required. 

SOLUTION  SULPHURATED  LIME. 

Liquor  .C  aids  Sulphurates,  N.  F.;  Vleminckx's  Lotion  or  Solu- 
tion. Each  100  mils  (Cc.)  represents  product  resulting  from 
16.5  Gm.  calcium  oxide  and  25  Gm.  sublimed  sulphur.  Depila- 
tory. 

SOLUTION  TAR  ALKALINE. 

Liquor  Picis  Alfyalinus,  N.  F.  Each  100  mils  (Cc.)  contains 
25  Gm.  tar,  12.5  Gm.  potassium  hydroxide.  Antiparasitic 
Dermic. 

SOLUTION,   THOMPSON'S.     See  Solution   Phosphorus. 

Solution  Tolu  for  Syrup.      See  Fluid  Tolu. 

SOLUTION,  VILLATE'S.     See  Mixture  Astringent. 

SOLUTION  ZINC  AND  ALUMINUM  COMPOUND. 

Liquor  Zinc!  ei  Alumini  Compositus,  N.  F.  Each  1000  mils 
(Cc.)  contains  200  Gm.  zinc  sulphate,  200  Gm.  aluminum 
sulphate,  0.6  Gm.  betanaphthol,  2  mils  oil  thyme.  Astringent, 
Antiseptic ;  externally. 

SOLUTION  ZINC  AND  IRON  COMPOUND. 

Liquor  Zinci  et  Fern  Compositus,  N.  F.;  Deodorant  Solu- 
tion. Each  1000  mils  (Cc.)  contains  200  Gm.  zinc  sulphate, 
200  Gm.  ferrous  sulphate,  65  Gm.  copper  sulphate,  0.6  Gm. 
betanaphthol,  2  mils  oil  thyme,  4  mils  hypophosphorous  acid. 

©  Solution  Zinc  Chloride,  Squibb  bottle,  Ib. 

Liquor  Zinci  Chloridi.  50  percent,  anhydrous  zinc  chloride. 
Disinfectant,  diluted,  about  1  Ib.  in  2  gallons  water;  Caustic, 
in  concentrated  form. 

Solutions,  Test  and  Volumetric.  See  Reagents   (Part  IV). 
Spanish  Flies.        See  Cantharides. 


If  difficulty  is  experienced  in  procuring  any  Squibb  product, 
in  the  original  packages  here  listed,  please  notify  us;  we 
shall  see  that  your  wants  are  met  promptly  and  satisfactorily. 


246        SQUIBB'S  MATERIA  MEDICA 

Sparteine  Sulphate,  Squibb  J/g-oz.  vial,  ;  15-gr.  vial, 
Sparleinai  Sulphas.  CisH26N2H.2SO4.5H2O.  Salt  of  alka- 
loid from  Scoparius  (Broom).  Colorless,  odorless,  crystals,  or 
a  white  powder;  saline,  slightly  bitter  taste.  I  Cm.  dissolves  in 
1.1  mils  (Cc.)  water,  3  alcohol;  insoluble  in  ether  or  chloro- 
form. Used  as  Heart  Stimulant  and  Diuretic.  Average  Dose: 
1/6  grain  (0.01  Gm.) ;  though  as  much  as  2  grains  has  been 
recommended  per  dose,  particularly  for  diuretic  action.  Anti- 
dotes: tannin,  then  emetics;  cathartics;  strong  hot  coffee; 
opium;  brandy.  (See  also  Tablets  [Part  II].) 

SPEARMINT. 

Mentha  Viridis.  Dried  leaves  and  flowering  tops  of  Mentha 
spicata  (Mentha  viridis;  Fam.  Labiate).  Carminative  Flavor- 
ing. Average  Dose:  60  grains  (4  Gm.). 

SPECIES,  LAXATIVE. 

Species  Laxatives,  N.  F.;  St.  Germain  Tea.  Senna  40%,  elder 
flowers  25%,  fennel  12.5%,  anise  12.5%,  potassium  bitar- 
trate  10%.  Average  Dose:  20  grains  (1.3  Gm.)  in  infusion. 

SPECIES,  PECTORAL. 

Species  Pectorales,  N.  F.;  Breast  Tea.  Althaea  40%,  colts- 
foot 20%,  licorice  15%,  anise  10%,  mullein  flowers  10%, 
orris  5%.  Average  Dose:  60  grains  (4  Gm.)  in  infusion. 

Specific  Gravity  Apparatus,  Squibb 

Consisting  of  a  tested  hydrometer,  thermometer,  and  red  and 
blue  litmus  paper.  Complete,  ;  without  thermometer,  ; 
hydrometer  alone,  ;  jar  alone, 

SPERMACETI. 

Cetaceum.  Concrete  fat  from  head  of  sperm  whale,  Physeter 
macrocephalus  (Fam.  Physeterida).  White,  unctuous  masses; 
faint  odor;  bland,  mild  taste.  Sp.  gr.  0.938  to  0.944.  Soluble 
in  ether,  chloroform,  oils;  nearly  insoluble  in  alcohol  (cold); 
insoluble  in  water.  Skin  Protective  and  Emollient,  but  used 
mainly  pharmaceutically. 

Spices. 

In  response  to  the  requests  of  physicians  for  powde*ed  spices 
of  unquestionable  identity  and  purity,  E.  R.  Squibb  &  Sons 
have  for  some  years  past  supplied  a  line  of  absolutely  pure, 
highest  quality  powdered  spices,  which  are  commended  to  all 
who  desire  condiments  of  distinctive  quality  and  free  from 
sophistication  of  any  kind.  The  whole  spices  are  selected  with 
the  greatest  care  and  first  assayed  to  make  sure  they  come  up 
to  the  high  standards  set  by  the  Squibb  Laboratories.  Being 
absolutely  pure  and  of  exceptional  strength,  the  Squibb  spices 
are  economical;  a  small  quantity  goes  a  great  way.  The  list 
comprises:  Allspice;  Cinnamon;  Cloves;  Ginger;  Mace; 
Mustard;  Nutmeg;  Paprika;  and  Pepper  (Black,  Red  Spe- 
cial Blend,  and  White).  See  respective  titles. 


SQUIBB'S  MATERIA  MEDICA       247 

SPIGELIA. 

Spigelia;  Pinkroot.  Dried  rhizome  and  roots  of  Spigelia 
marilandica  (Fam.  Loganiacea) .  Aromatic  odor;  pungent,  bit- 
ter taste.  Teniafuge.  Average  Dose:  60  grains  (4  Gm.). 

SPIKENARD.     See  Aralia. 

SPINDLE  TREE:    See  Euonymus.* 

SPIRIT  ACID  FORMIC. 

Spiritus  Acidi  Formici,  N.  F.;  Spirit  of  Ants.  1000  mils 
(Cc.)  contain  40  mils  formic  acid  (25%),  735  alcohol,  and 
water.  Rubefacient  externally;  rarely  used  internally  as  diffusi- 
ble Stimulant.  Average  Dose:  1  fluidrachm  (4  mils). 

SPIRIT  AMMONIA  ANISATED. 

Spirilus  Ammonia  Anisatus,  N.  F.  3  vol.  percent,  anethol, 
20  ammonia  water,  alcohol  q.  s.  Aromatjc  Carminative,  Ex- 
pectorant. Average  Dose:  15  minims  (1  mil  [Cc.]). 

®  Spirit  Ammonia  Aromatic,  Squibb 

g.  s.  bottle,  pint          ;   J/^  P"1' 

Spirilus  Ammonia  Aromalicus.  100  mils  (Cc.)  contain  3.4 
Gm.  ammonium  carbonate  and  9  mils  ammonia  water,  with 
oils  of  lemon,  nutmeg  and  lavender,  alcohol  and  water.  Sp.  gr. 
about  0.900.  Stimulant,  Aromatic  Alkali,  Carminative. 
Average  Dose:  30  minims  (2  mils),  diluted. 

SPIRIT  ANISE. 

Spiritus  Anisi.  10  volume  percent,  oil  anise,  in  alcohol.  Aro- 
matic Carminative;  Flavoring.  Average  Dose:  30  minims  (2 
mils  [Cc.]). 

SPIRIT  ANTS.     See  Spirit  Acid  Formic. 

SPIRIT  BAY  COMPOUND.     See  Spirit  Myrcia  Compound. 

SPIRIT  BITTER  ALMOND. 

Spiritus  Amygdala  Amara.  1  volume  percent,  true  oil  bitter 
almond,  in  alcohol  (80)  and  water  (19).  Cough  Sedative; 
Flavoring.  Average  Dose:  8  minims  (0.5  mil  [Cc.]). 

©  SPIRIT  CAMPHOR. 

Spiritus  Camphors;  Tincture  Camphor.  100  mils  (Cc.)  con- 
tain 10  Gm.  camphor,  in  alcohol.  Rubefacient;  Antispasmodic, 
Stimulant.  Average  Dose:  15  minims  (1  mil),  diluted. 

SPIRIT  CARDAMOM  COMPOUND. 

Spirilus  Cardamomi  Compositus,  N.  F.  10  vol.  percent,  oil 
cardamom,  10  oil  orange,  1  oil  cinnamon,  0.5  oil  clove,  0.5 
anethol,  0.02  oil  caraway,  in  alcohol.  Carminative;  Flavoring. 


The  Squibb  products  are  recognized  everywhere  as  the  Quality 
Standard.  They  are  of  uniform  purity  and  strength,  hence 
therapeutically  dependable.  When  ordering  or  prescribing  med- 
icinal products,  you  will  do  well  always  to  specify  SQUIBB'S. 


248       SQUIBB'S  MATERIA  MEDICA 

©  SPIRIT  CHLOROFORM. 

Spiritus  Chloroformi ;  Chloric  Ether.  6  volume  percent, 
chloroform,  in  alcohol.  Counter-irritant,  Anodyne;  Antispas- 
modic.  Carminative.  Average  Dose:  30  minimi  (2  mils  [Cc.]), 
diluted. 

SPIRIT  CINNAMON. 

Spiritus  Cinnamomi.  10  volume  percent,  oil  cinnamon,  in  alco- 
hol. Aromatic  Carminative.  Average  Dose:  30  minims  (2 
mils  [Cc.]). 

©  SPIRIT  ETHER. 

Spirilus  dElheris;  often  erroneously  designated  as  Hoffmann's 
Anodyne.  32%  volume  percent,  ether,  in  alcohol.  Carmina- 
tive, Antispasmodic,  Stimulant.  Average  Dose:  I  fluidrachm 
(4  mils  [Cc.]). 

Spirit  Ether  Compound,  Squibb  bottle,  pint  ;  ]4  pint 
Spiritus  /Elheris  Compositus  Hoffman's  Anodyne.  2.5  vol- 
ume percent,  genuine  ethereal  oil.  Each  100  mils  (Cc.)  contains 
2.5  mils  (Cc.)  ethereal  oil,  32.5  mils  ether,  and  alcohol. 
The  ethereal  oil  used  is  a  product  made  in  strict  accordance 
with  N.  F.  directions;  not  the  nondescript  distillate  from  grapes, 
nor  the  indeterminate  residue  from  the  ether  still  often  marketed 
as  "oil  of  wine."  Stimulant  Antispasmodic,  Carminative. 
Average  Dose:  1  fluidrachm  (4  mils  [Cc.]),  diluted. 

©  Spirit  Ether  Nitrous,  Squibb 

bottle,  pint,          ;  '/£  pint, 

Spin /us  /Etheris  Niirosi;  Sweet  Spirit  Nitre.  Prepared  at 
frequent  intervals,  to  insure  reliability  in  strength.  A  special 
laboratory  process  affords  a  product  better  than  that  produced 
by  method  described  in  U.  S.  P.  It  is  more  uniform  in  con- 
stitution, and  the  therapeutic  results  from  its  use  are  more  gen- 
erally satisfactory.  Assays  about  4  percent,  ethyl  nitrite. 
Volatile,  inflammable,  clear  liquid;  pungent  odor;  sharp,  burn- 
ing taste.  Sp.  gr.  about  0.823.  Mild  Diuretic,  Diaphoretic. 
Average  Dose:  30  minims  (2  mils  [Cc.]).  Incompatible  with 
antipyrine,  acetanilid,  acetphenetidin,  fluidextract  buchu,  mor- 
phine salts,  and  iodides  (when  it  is  acid).  Should  be  kept 
in  dark-amber  bottles,  in  cool  place  remote  from  lights  and  fire. 

SPIRIT  GLONOIN.     See  Spirit  Glyceryl  Trinitrate. 

0  SPIRIT  GLYCERYL  TRINITRATE. 

Spirilus  C/pcerji/is  Nilratis;  Spirit  Glonoin;  Solution  Nitro- 
glycerin.  Alcoholic  solution  containing  I  percent.  CsHs- 
(NOs)-}.  Vaso-dilator;  slower  than  amyl  nitrite.  Average 
Dose:  1  minim  (0.06  mil  [Cc.]).  Antidotes:  atropine;  extract 
ergot;  strychnine;  stimulants.  NOTES:  Great  care  must  be  exer- 
cised in  handling  and  storing  this  spirit;  dangerous  explosion 
may  result  if  any  considerable  quantity  is  spilled  and  the  alcohol 
lost  by  evaporation.  If  spilled,  pour  solution  potassium  hydrox- 
ide over  it  at  once.  (See  also  Tablets  Nitroglycerin  [Part  II].) 


SQUIBB'S  MATERIA  MEDICA        249 

Spirit  Hartshorn.        See  Ammonia  Water. 

SPIRIT  JUNIPER. 

Spiritus  Juniperi.  5  volume  percent,  oil  juniper,  in  alcohol. 
Diuretic.  Average  Dose:  2J/2  fluidrachms  (10  mils  [Cc.]). 

SPIRIT  JUNIPER  COMPOUND. 

Spiritus  Juniperi  Compositus.  0.4  vol.  percent,  oil  juniper, 
and  0.05  each  oils  fennel  and  caraway,  in  alcohol  and  water. 
Diuretic.  Average  Dose:  2*/2  fluidrachms  (10  mils  [Cc.]). 

SPIRIT  LAVENDER. 

Spiritus  LavandulcE.  5  volume  percent,  oil  lavender  flowers, 
in  alcohol.  Aromatic;  Carminative.  Flavoring.  Average 
Dose:  30  minims  (2  mils  [Cc.]). 

Spirit  Lavender  Compound.    See   Tincture   Lavender   Com- 
pound. 

SPIRIT    MINDERERUS.     See    Solution   Ammonium   Acetate. 

SPIRIT  MUSTARD. 

Spiritus   Sinapis,   N.   F.      2   vol.   percent,   volatile   oil   mustard, 
in  alcohol.     Counter-irritant. 

SPIRIT  MYRCIA  COMPOUND. 

Spirilus  Myrcice  Compositus,  N.  F.;  Bay  Rum.  Each  1000 
mils  (Cc.)  contains  8  mils  oil  bay,  0.5  oil  orange,  0.5  oil 
pimenta,  610  alcohol,  water  q.  s.  Refreshing  Ablution. 

Spirit  Nitre,  Sweet,  or  Spirit  Nitrous  Ether.    See  Spirit 
Ether  Nitrous. 

SPIRIT  NITROGLYCERIN.     See  Spirit  Glyceryl  Trinitrate. 

Spirit  Orange  Compound,  Squibb 

bottle,    pint          ;    J/£   Pm' 

Spirilus  Auraniii  Compositus.  20,  5,  2,  and  0.5  vol.  percent, 
respectively  of  oils  orange  peel,  lemon,  coriander  and  anise,  in 
alcohol.  Flavoring. 

®  Spirit  Peppermint,  Squibb    bottle,  pint,        ;  %  pint, 

Spirilus  Menihce  Piperits;  Essence  Peppermint.  From  bruised 
peppermint  leaves  and  oil  peppermint  (10  percent,  by  volume). 
Aromatic  Carminative.  Average  Dose :  30  minims  (2  mils 
[Cc.]),  well  diluted  or  on  sugar. 


Since  we  make  only  one  quality  of  each  product,  that  best 
suited  to  the  purposes  intended,  the  specification  "Squibb's" 
is  not  open  to  various  interpretations,  but  has  a  plain,  positive 
meaning.  When  ordering  or  prescribing,  specify  SQUIBB'S. 


250       SQUIBB'S  MATERIA  MEDICA 
SPIRIT,  PERFUMED. 

Spiritus  Odoratus,  N.  F.;  Cologne.  Each  1000  mils  (Cc.) 
contains  15  mils  oil  bergamot,  8  oil  lemon,  7  oil  rosemary,  4 
oil  lavender,  4  oil  orange  flowers,  2  acetic  ether,  water  120, 
alcohol  q.  s.  Refreshing,  fragrant  ablution. 

SPIRIT  SPEARMINT. 

Spiriius  Menthol  Viridis;  Essence  of  Spearmint.  From  bruised 
leaves  and  oil  spearmint  (10  vol.  percent.),  with  alcohol. 
Aromatic  Carminative;  Flavoring.  Average  Dose:  30  minims 
(2  mils  [Cc.]). 

SPIRIT  TURPENTINE.    See  Oil  Turpentine. 

SPIRIT  VANILLIN  COMPOUND. 

Spin/us  Vanillmi  Compositus,  N.  F.  Each  100  mils  (Cc.) 
contains  20  Gm.  vanillin,  5  mils  oil  orange,  1  oil  cardamom,  0.5 
oil  cinnamon,  in  alcohol.  Flavoring. 

SPRAY  AROMATIC  OIL. 

Nebula  Aromallca,  N.  F.  100  mils  (Cc.)  contain  0.2  Gm. 
carbolic  acid,  0.2  Gm.  menthol,  0.1  Gm.  thymol,  0.3  camphor, 
0.3  Gm.  benzoic  acid,  0.2  mil  eucalyptol,  0.2  mil  oil  cinna- 
mon, 0.2  oil  clove,  0.5  mil  methyl  salicylate,  liquid  petrola- 
tum q.  s. 

SPRAY  EUCALYPTOL. 

Nebula  Eucalyptolis,  N.  F.  5  vol.  percent,  eucalyptol  in 
Kquid  petrolatum.  Antiseptic  and  Deodorant  spray  for  chronic 
inflammations  of  respiratory  musosit. 

SPRAY  MENTHOL. 

Nebula  Menlholis,  N.  F.  100  mils  (Cc.)  contain  2  Gm.  men- 
thol, in  liquid  petrolatum.  Nasal  spray. 

SPRAY  MENTHOL  COMPOUND. 

Nebula  Mentholts  Composita,  N.  F.  100  mils  (Cc.)  contain 
1  Gm.  menthol,  1  Gm.  camphor,  0.5  mil  methyl  salicylate,  0.2 
mil  eucalyptol,  0.2  mil  oil  cinnamon,  in  liquid  petrolatum.  Aro- 
matic, Antiseptic  throat  spray. 

SPRAY  THYMOL. 

Nebula  Thymolis,  N.  F.  100  mils  (Cc.)  contain  1  Gm.  thy- 
mol, in  liquid  petrolatum.  Antiseptic  throat  spray. 

SPURRED  RYE.    See  Ergot. 

SQUAW  ROOT.    See  Caulophyllum. 

Squibb's   Diarrhea   Mixture.  See  Tincture  Opium  Compound. 


SQUIBB'S  MATERIA  MEDICA       251 

©Squill,   Squibb 

Ground  for  Percolation  bottle,  lb. 

Scilla.  Fleshy,  inner  scales  of  bulb  of  Urginea  maritima  (Fam. 
Liliacece),  cut  into  thin  slices  and  carefully  dried,  the  central 
portions  being  rejected.  Physiologically  assayed  by  U.  S.  P. 
method.  Expectorant,  Emetic,  Nauseant.  Average  Dose: 
1  !/o  grains  (0.1  Gm.).  (See  also  Fluidextract;  Syrup;  Vine- 
gar.) 

Stannous  Chloride  Reagent.  See  Reagents  (Part  IV). 

STAPHISAGRIA. 

Staphisagria ;  Stavesacre  Seed.  Ripe  seed  of  Delphinium 
Staphisagria  (Fam.  Ranunculacea) .  Odor  slight;  taste  in- 
tensely bitter,  acrid.  Antiparasitic  Dermic,  Alterative.  Aver* 
age  Dose:  I  grain  (0.065  Gm.).  Antidotes:  tannin,  then 
emetics;  chloral  hydrate;  chloroform  by  inhalation;  ammonia 
or  digitalis. 

STAR  GRASS.    See  Aletris. 

®  Starch,  Corn,  Squibb  tin,  lb. 

Amylum.  Starch  separated  from  grain  of  Zea  Mays  (Fam. 
Cramineas).  Dusting-powder,  Diluent. 

STAVESACRE.     See  Staphisagria. 

Sterile  Ergot,  Squibb 

box  of  6x1   Cc.  ampuls 

box  of   12x1    Cc.  ampuls 

A  sterile,  non-alcoholic,  physiologically  tested  and  standardized 
preparation  of  best  Spanish  ergot,  intended  for  hypodermic  or 
intramuscular  use  in  uterine  inertia,  metrorrhagia,  post-partum 
hemorrhage,  collapse,  etc.  Each  mil  (Cc.)  represents  2  Gm. 
ergot. 

STILLINGIA. 

Stillingia;  Queen's  Root;  Silver  Leaf.  Dried  roots  of  Stilllngia 
s'yhatica  (Fam.  Euphorbiacece) .  Odor  distinct;  taste  bitter, 
acrid  and  pungent.  Used  as  Alterative,  Expectorant,  Siala- 
gogue.  Average  Dose:  30  grains  (2  Gm.).  (See  also  Fluid- 
extract.) 

STOKES'  EXPECTORANT.     See  Mixture,  Pectoral,  Stokes. 

STOKES'    ST.    JOHN    LONG'S    LINIMENT.      See    Liniment    Tur- 
pentine, Acetic. 

The  founder  of  the  House  of  Squibb,  Dr.  Edward  R.  Squibb, 
not  only  had  high  ideals,  but  lived  and  labored  for  them;  and, 
in  the  words  of  William  Miller  Bartlett,  "the  House  of  Squibb 
stands  today  as  a  living  monument  to  the  honor,  integrity,  zeal 
and  devotion  of  its  founder." 


252        SQUIBB'S  MATERIA  MEDICA 

STORAX. 

Slyrax;  Liquid  Storax.  Balsam  from  wood  and  inner  bark  of 
Liquidambar  orientalis  (Fam.  Hamamelidaceai).  Semihquid, 
grayish,  sticky,  opaque  mass;  agreeable  odor;  balsamic,  acrid 
taste.  Soluble  in  equal  weight  warm  alcohol;  almost  com- 
pletely soluble  in  ether;  insoluble  in  water.  Antiparasitic  Der- 
mic,  Expectorant.  Average  Dose :  1 5  grains  ( 1  Gm.) . 

0  STRAMONIUM. 

Stramonium;  Thornapple  Leaves;  Jamestown,  or  Jimson,  Weed. 
Dried  leaves  of  Datura  Stramonium  or  of  D.  Talula  (Fam. 
Solanacece),  assaying  not  less  than  0.25  percent,  alkaloids. 
Odor  heavy,  narcotic;  taste  nauseous.  Nerve  Sedative,  Anti- 
spasmodic,  Anodyne.  Average  Dose:  1  grain  (0.065  Gm.). 
Antidotes:  tannin;  apomorphine  hypodermically ;  morphine; 
ammonia  by  inhalation.  See  also  Extract;  Fluidextract; 
Tincture.) 

Strontium  Acetate,  Squibb 

bottle,   Ib.          ;    %  lb.          ;   oz. 

Sr(CoH3O2)2.1/2HoO.  White,  crystalline  powder.  Soluble 
in  water.  Anthelmintic ;  also  Reagent.  Dose :  40  grains  (2.6 
Gm.),  in  water  and  glycerin,  twice  daily  for  five  days. 

Strontium  Arsenite,  Squibb  bottle,  oz. 

Sr(AsO2)2.4HoO.  White  powder.  Soluble  difficultly  in 
water.  Alterative,  Antiperiodic;  in  chronic  skin  diseases, 
malaria,  etc.  Dose:  Vso  to  Via  grain  (0.002  to  0.004  Gm.), 
thrice  daily.  Antidotes:  arsenic  antidote  or  magnesia  and  milk; 
emetics;  stimulants. 

Strontium  Bromide,  Squibb 

(Crystals)  bottle,  lb.         ;         '/j  lb.         ;   oz. 

Strontii  Bromidum.  SrBro.6H2O.  Free  from  barium.  Color- 
less, odorless,  bitter-saline  crystals.  1  Gm.  dissolves  in  0.35 
mil  (Cc.)  water;  soluble  in  alcohol;  insoluble  in  ether.  Nerve 
Sedative,  similar  to  sodium  bromide ;  also  Reagent.  Aver- 
age Dose:  15  grains  (1  Gm.).  Incompatible  in  solution  with 
mineral  acids,  alkaloidal  salts,  and  salts  of  heavy  metals. 

STRONTIUM  CARBONATE. 

Strontii  Carbonas,  N.  F.  SrCOg.  White,  odorless,  tasteless 
powder,  insoluble  in  ordinary  solvents.  Used  technically. 

Strontium   Iodide,   Squibb         g.  s.  bottle,  %  lb.         ;  oz. 

Slronlii  loJidum.  Srl2.6H2O.  Almost  colorless,  odorless,  bit- 
ter-saline, deliquescent,  hexagonal  plates,  darkening  on  expo- 
sure. 1  Gm.  dissolves  in  0.2  mil  (Cc.)  water;  soluble  in 
alcohol,  slightly  soluble  in  ether.  A  deeply  colored  article 
should  not  be  dispensed.  Alterative,  like  potassium  iodide; 
Expectorant.  Average  Dose:  5  grains  (0.3  Gm.).  Incom- 
patible in  solution  with  alkaloidal  salts,  chloral  hydrate,  mineral 
acids,  alkalies  and  metallic  salts  generally. 


SQUIBB'S  MATERIA  MEDICA       253 
Strontium  Lactate,  Squibb  bottle,  14  lb.        ;  oz. 

White,  granular  powder;  slightly  bitter  taste.  Soluble  in  4 
parts  water;  in  alcohol.  Used  as  Alterative,  Vermicide,  Anti- 
catarrhal;  in  rheumatism,  chorea,  worms,  nephritis,  etc.  Dose: 
5  to  1 5  grains  (0.3  to  1  Gm.) ;  vermicide,  30  grains  (2  Gm.) 
twice  daily  for  5  days. 

Strontium  Salicylate,  Squibb 

bottle,  lb.          ;  %  lb.          ;  oz. 

Stronlii  Salicylas.  Sr(C-H5O3)2.2H2O.  White,  crystalline, 
odorless,  powder;  sweetish,  saline  taste.  I  Gm.  dissolves  in 
19  mils  (Cc.)  water,  61  alcohol.  Antirheumatic,  Intestinal 
Antiseptic.  Average  Dose:  15  grains  (1  Gm.).  Incompatible 
in  solution  with  ferric  salts,  mineral  acids,  quinine  salts,  silver 
nitrate  and  lead  acetate. 

©  Strophanthin,  Squibb  5-grain  vial 

Strophanihinum.  Glucoside  (or  mixture  of  glucosides)  from 
Strophanthus.  Exceedingly  powerful  and  poisonous,  hence 
great  caution  should  be  used  in  handling  it.  White  or  faintly 
yellowish,  crystalline,  intensely  bitter  powder.  Soluble  freely 
in  water  or  diluted  alcohol;  nearly  insoluble  in  chloroform  or 
ether.  Heart  Stimulant,  like  digitalis,  but  acts  more  rapidly 
and  is  excreted  sooner;  hence  preferred  in  emergencies,  used 
hypodermically.  Absorption  from  alimentary  canal  variable, 
hence  oral  use  inadvisable.  Average  Dose :  by  mouth,  i/GO 
grain  (0.001  Gm.) ;  intravenously,  I/go  grain  (0.00075  Gm.). 
Antidotes:  emetics;  atropine  or  pilocarpine  subcutaneously; 
picrotoxin;  camphor  or  brandy  as  stimulants. 

STROPHANTHIN     CRYSTALLIZED      OR      G-STROPHANTHIN.    See 
Ouabain. 

©  STROPHANTHUS. 

Strophanthus.  Dried  ripe  seeds  of  Sirophanthus  Kombe  or  of 
S.  hispidus  (Fam.  Apocynanacea),  deprived  of  their  long  awns. 
Action  same  as  that  of  strophanthin.  Odor  slight,  taste  very 
bitter.  Average  Dose:  1  grain  (0.065  Gm.).  (See  also  Tincture.) 

©  Strychnine,  Squibb 

*  Crystals  bottle,  oz.         ;  J/g-oz.  vial 

Powdered  bottle,  oz.         ;  J/g-oz.  vial 

Strychnina.  CoiJ-^OoNo.  Alkaloid  from  Nux  Vomica. 
Colorless,  transparent,  odorless,  intensely  bitter  crystals,  or 
white  powder.  1  Gm.  dissolves  in  6420  mils  (Cc.)  water,  136 
alcohol,  5  chloroform;  very  slightly  in  ether.  Bitter  Tonic; 
Nerve,  Respiratory  and  Cardiac  Stimulant.  Average  Dose :  1/40 
grain  (0.0015  Gm.),  in  pills  or  tablets.  Antidotes:  tannin, 
then  emetics;  chloral  hydrate  and  bromides  per  rectum;  chloro- 
form by  inhalation  if  required. 

The  Squibb  Ideals  have  taken  concrete  form  in  the  Squibb 
Products;  these  are  universally  recognized  as  standards  of 
uniform  Purity  and  Efficacy,  that  is,  general  Excellence  and 
Reliability.  Specify  SQUIBB'S  when  prescribing  or  ordering. 


254        SQUIBB'S  MATERIA  MEDICA 

Strychnine  Arsenate,  Squibb  I/8-oz.  vial 

C2lH22O2N2.H3AsO4.l/2H2O.  White,  very  bitter  needles  or 
powder.  Soluble  in  about  70  parts  water.  Used  as  Alterative 
and  Nerve  Stimulant;  in  tuberculosis,  skin  diseases,  obstinate 
malaria,  nervous  debility,  etc.  Dose:  Veo  to  1/15  grain  (0.001 
to  0.004  Gm.);  hypodermically,  3  to  10  minims  (0.2  to  0.6 
mil  [Cc.])  of  J/2  percent,  suspension  in  liquid  petrolatum  once 
daily. 

Strychnine  Arsenite,  Squibb  K-OZ.  vial 

C^lt^OaNo-HAsOo.  White  powder.  Sparingly  soluble  in 
water.  Action  and  dose:  as  of  preceding. 

Strychnine  Glycerophosphate,  Squibb 

bottle,  oz.         ;  J/g-oz.  vial 

Strychnines  Glycerophosphas,  N.  F.  White,  very  bitter  powder. 
1  Gm.  dissolves  in  350  mils  (Cc.)  water,  310  alcohol;  slightly 
soluble  in  ether  or  chloroform.  Average  Dose:  !/4o  grain 
(0.0015  Gm.). 

Strychnine  Hydrobromide,  Squibb  Ve-oz-vial 

C2iH22O2No.HBr.     Small,  white  needles.  Soluble  in  alcohol, 

about  55  parts  water.  Used  chiefly  in  chronic  alcoholism, 
insomnia  from  overwork,  etc. 

Strychnine  Hydrochloride,  Squibb  Y&-OT..  vial 

CoiH22OoN2.HCl.2H2O.  White  efflorescent  needles.  Sol- 
uble in  about  50  parts  water. 

0  Strychnine  Nitrate,  Squibb  '/8-oz.  vial 

Strychnine  Nitras.  C-n^oOoNo.HNOs.  Colorles-s,  glisten- 
ing, odorless,  intensely  bitter  needles;  or  white  powder.  I 
Gm.  dissolves  in  42  mils  (Cc.)  water,  150  alcohol,  50  glycerin, 
105  chloroform;  insoluble  in  ether.  Used  chiefly  in  dipsoma- 
nia hypodermically.  Incompatibles  of  strychnine  salts  in  gen- 
eral: alkalies,  alkali  carbonates,  iodides,  bromides,  arsenates, 
arsenites,  etc.  (See  also  Tablets  [Part  II].) 

Strychnine  Phosphate,  Squibb  Y&-OZ.  vial 

(Co1H22O1>N2)o.H;jPO4.9H2O.  White  powder  or  shining 
needles.  Soluble  slightly  in  water. 

©  Strychnine  Sulphate,  Squibb 

Crystals  or  *Powdered  bottle,  oz.  ;  |/£-oz.  vial 
Strychnin*  Sulphas.  (CoiHooOoNo^.HoSO^HoO.  Color- 
less  or  white,  odorless,  intensely  bitter,  efflorescent  crystals  or 
powder.  1  Gm.  dissolves  in  32  mils  (Cc.)  water,  81  alcohol, 
220  chloroform;  freely  soluble  in  glycerin;  insoluble  in  ether. 
Action,  dose  and  antidotes:  as  of  strychnine  alkaloid.  (See 
also  Tablets  [Part  II].) 


SQUIBB'S  MATERIA  MEDICA       255 

STRYCHNINE  VALERATE. 

Strychnine  Valeras,  N.  F.  White  powder;  odor  of  valerian; 
intensely  bitter  taste.  Sparingly  soluble  in  water,  ether ;  soluble  in 
alcohol,  chloroform.  Average  Dose:  ViO  grain  (0.0015  Gm.). 

fSTYPTlciN.     Brand  of  Cotarnine  Hydrochloride. 

fSTYPTOL. 

Cotarnine  Phthalate  Neutral.  Yellow,  bitter  powder.  Soluble 
freely  in  water  or  alcohol.  Action  and  dose:  as  of  cotarnine 
hydrochloride. 

SUET  BENZOINATED. 

Sevum  Benzoinatum,  N.  F.  Prepared  suet  carrying  3  percent, 
benzoin.  Ointment  Base. 

SUET  PREPARED. 

Sevu/n  Praparatum.  Internal  fat  of  abdomen  of  sheep,  purified 
by  melting  and  straining.  White,  nearly  odorless,  solid  fat; 
bland  taste  when  fresh,  becoming  rancid  on  exposure.  1  Gm. 
dissolves  in  about  60  Gm.  ether,  2  benzin;  insoluble  in  water, 
cold. alcohol.  Used  in  preparation  of  ointments  and  cerates. 

©  SUGAR. 

Saccharum;  Sucrose.  Ci^HtaOu.  From  cultivated  varieties 
of  Saccharum  officinarum  (Fam.  Craminea),  from  Beta  "vul- 
garis  (Fam.  Chenopodiacece),  etc.  1  Gm.  dissolves  in  0.5 
mil  (Cc.)  water,  170  alcohol;  insoluble  in  chloroform,  ether. 

Sugar  of  Lead.        See  Lead  Acetate. 

©  Sugar  of  Milk,  Squibb  tin,  Ib.         ;  !4  lb. 

Saccharum  Lactis ;  Lactose.  Ci2H22Oll-H2O.  Impalpable 
powder,  having  been  bolted  through  a  No.  120  silk  bolting 
cloth.  Unless  properly  purified,  milk  sugar  contains  small  per- 
centages of  other  constituents  of  milk.  The  article  here  listed 
is  distinguishable  from  other  grades  in  being  free  from  traces 
of  casein  and  butter-fat  that  cause  fermentation  when  the 
article  is  used  to  modify  milk;  also  perfectly  free  from  cane 
sugar,  starch  and  other  impurities.  Hence  of  excellent  purity, 
and  especially  adapted  for  use  in  milk  modification  and  for 
compounding  powders,  etc.  As  Milk  Sugar  readily  absorbs 
odors,  and  in  consequence  becomes  contaminated,  this  firm 
supplies  it  only  in  tins,  not  in  pasteboard  boxes.  It  should  be 
kept  tightly  closed  and  remote  from  odorous  substances.  White, 
odorless  powder;  less  sweet  than  cane  sugar,  less  liable  to  fer^ 
ment.  1  Gm.  dissolves  in  4.9  mils  water;  almost  insoluble 
in  alcohol;  insoluble  in  ether  or  chloroform.  Nutritive,  Diur- 
etic; largely  used  to  modify  cow's  milk  in  feeding  of  infants. 
Dose  (diuretic)  :  3  or  4  ounces  per  day. 


The  Squibb  Label  on  a  package  is  a  positive  guaranty  for  the 
uniform  Purity  and  Reliability  of  the  product.  We  make  only 
ONE  quality:  the  SQUIBB  quality;  and  our  prices  are  as  low 
as  they  can  be  made  for  that  quality.  Specify  SQUIBB'S. 


256       SQUIBB'S  MATERIA  MEDICA 

SULPHONAL.     Brand  of  Sulphonmethane. 

0  Sulphonethylmethane,  Squibb  bottle,  oz. 

Sulphonethymethanum  ;  Diethylsulphonemethylethylmethane ; 
Trional.  CgHi8S2O4.  Colorless,  odorless,  bitter  scales.  I  Gm. 
dissolves  in  200  mils  (Cc.)  water;  readily  in  alcohol  or  ether. 
Triturated  with  chloral  hydrate,  it  yields  a  liquid  or  soft  mass. 
Hypnotic,  Nerve  Sedative.  Average  Dose:  12  grains  (0.75 
Gm.),  in  hot  water  or  tea.  (See  also  Tablets  [Part  II].) 

©  Sulphonmethane,  Squibb  bottle,  oz. 

Sulphonmethanum ;  Diethylsulphonemethylmetnane;  Sulphonal. 
C7HieS2O4.  Colorless,  odorless,  almost  tasteless  crystals;  or 
white,  crystalline  powder.  1  Gm.  dissolves  in  365  mils  (Cc.) 
water,  60  alcohol,  1 1  chloroform,  64  ether.  Hypnotic,  Nerve 
Sedative.  Average  Dose:  12  grains  (0.75  Gm.),  in  hot  water  or 
tea.  (See  also  Tablets  [Part  II].) 

0  Sulphur  Precipitated,  Squibb 

carton,  Ib.         ;  ]/4  Ib. 

Sulphur  Pracipitalum ;  Lac  Sulphuris;  Milk  of  Sulphur.  S. 
Much  of  the  precipitated  sulphur  of  the  market  contains  cal- 
cium sulphate  due  to  use  of  sulphuric  acid  in  the  precipitation. 
The  product  here  quoted  is  precipitated  from  lime  solution  by 
hydrochloric  acid  and  the  soluble  calcium  chloride  thoroughly 
washed  out.  It  will  be  found  free  from  either  acid  or  alkali. 
Fine,  pale-yellow,  odorless,  tasteless  powder.  Soluble  in  car- 
bon disulphide,  benzin,  oil  turpentine  and  many  other  oils; 
also  in  ether  or  chloroform.  Mild  Cathartic;  Antipar- 
asitic  Dermic.  Average  Dose:  60  grains  (4  Gm.). 

©  Sulphur  Sublimed,  Squibb  carton,  Ib., 

Sulphur  Sublimatum;  Flowers  of  Sulphur.  S.  Fine-yellow 
powder;  slight  odor;  faintly  acid  taste.  Soluble  same  as 
precipitated  sulphur.  Used  chiefly  as  Dermic,  rarely  as  Laxa- 
tive. Average  Dose:  60  grains  (4  Gm.). 

©  Sulphur  Washed,  Squibb  carton,  Ib. 

Sulphur  Lolum.  S.  Thoroughly  washed  with  ammonia  water 
and  finally  with  water.  Action  and  dose:  as  of  preceding. 
(See  also  Reagents  [Part  IV].) 

SULPHUR  IODIDE. 

Sulphuris  lodiclum,  N.  F.  Fused  combination  of  washed  sul- 
phur 20  percent,  and  iodine  80  percent.  Grayish-black, 
brittle  masses;  iodine  odor;  acrid  taste.  Almost  insoluble  in 
water;  soluble  in  about  60  parts  glycerin;  partially  soluble  in 
alcohol  or  ether.  Obsolescent  Antiparasitic  Dermic. 

SUMACH.     See  Rhus  Glabra. 


SQUIBB'S  MATERIA  MEDICA        257 

SUMBUL. 

Sumbul;  Musk- root.  Dried  rhizome  and  roots  of  Ferula  Sum- 
bul  (Fam.  UmbellifertE).  Odor  strong,  musk-like;  taste  bitter. 
Used  as  Nerve  Stimulant  and  Antispasmodic ;  in  hysterical 
conditions.  Average  Dose:  30  grains  (2  Gm.).  (See  also 
Fluidextract.) 

SUN    CHOLERA    MIXTURE.     See    Mixture    Opium    and    Rhubarb 
Compound. 

SUPPOSITORIES  BOROGLYCERIN. 

Suppositoria  Boroglycerini,  N.  F.  1.25  Gm.  glycerite  boro- 
glycerin,  1.25  Gm.  glycerin,  1.67  Gm.  glycerinated  gelatin. 
Antiseptic. 

©  Suppositories  Glycerin,  Squibb 

bottles  of    6,  in  boxes  of  6  bottles,  per  doz.  bottles 
bottles  of  12,  in  boxes  of  6  bottles,  per  doz.  bottles 
Suppositoria  Clycerini.     Moulded  recta!  suppositories  made  with 
steanc  acid  and  a  little  sodium  carbonate  monohydrated.     Each 
contains  3   grammes    (46   grains)    glycerin ;    cone-shape.     Laxa- 
tive  in   action. 

Suppositories  Glycerin,  Infants'  Long,  Squibb 

bottles  of    6,  per  doz.  bottles 
bottles  of  12,  per  doz.  bottles 
Each  contains  26J/4  grains  pure  glycerin ;  special  size  for  infants. 

SUPRARENALS   DRIED. 

Suprarenalum  Siccum.  Suprarenal  glands  of  the  sheep  (Ovi's 
aries)  or  ox  (Bos  taurus)  freed  from  fat,  cleaned,  dried,  and 
powdered.  Contains  about  0.5  percent,  epinephrine.  Light  yel- 
lowish-brown powder,  of  slight  odor;  partially  soluble  in 
water;  1  part  equals  about  6  parts  fresh  gland.  Alterative, 
Vaso-constrictor ;  in  Addison's  disease,  diabetes  msipidus,  Base- 
dow's  disease,  recurrent  hemorrhages,  etc.  Average  Dose : 
grains  (0.25  Gm.). 

SYDENHAM'S  LAUDANUM.        See   Tincture   Opium   with   Saffron. 
SYKOSE.     Brand  of   Benzosulphinide   (Saccharin). 

©  SYRUP  (SIMPLE). 

Syrupus ;  Syrup.  Aqueous  solution  of  sugar,  containing  85 
Gm.  of  latter  in  each  100  mils  (Cc.).  Sp.  gr.  1.313.  Used 
pharmaceutically. 

This  house  supplies  only  one  quality  of  each  product:  that  best 
suited  to  the  purposes  intended.  The  specification  "Squibb's" 
is  not  open  to  various  interpretations;  it  has  a  plain,  posi- 
tive meaning.  Therefore,  when  prescribing,  specify  SQUIBB'S. 


258        SQUIBB'S  MATERIA  MEDICA 

SYRUP  ACACIA. 

Syrupus  Acacia;  Syrupus  Gummosus;  Syrup  Gum.  10  per- 
cent. acacia.  Best  prepared  extemporaneously  in  small  quan- 
tities at  a  time,  and  kept  well  stoppered,  in  cool  place.  Vehicle 
Demulcent. 

SYRUP  ACID  CITRIC. 

Syrupus  Acidi  Cilrici;  Syrup  Lemon.  100  mils  (Cc.)  contain 
I  Gm.  citric  acid  in  syrup  flavored  with  tincture  fresh  lemon 
peel.  Flavoring  ingredient.  Does  not  keep  well. 

Syrup  Acid  Hydriodic,  Squibb  pint, 

Essentially  official  Syrupus  Acidi  Hydriodici.  Contains  12.5 
vol.  percent,  diluted  hydriodic  acid,  or  1  .3  to  1  .45  Gm.  HI  in 
100  mils  (Cc.),  but  made  according  to  an  improved  formula 
which  yields  a  more  stable  product  than  U.  S.  P.  process. 
Alterative;  chiefly  in  chronic  bronchitis,  scrofula,  rheumatic 
conditions,  etc.  Average  Dose:  1  fluidrachm  (4  mils).  Keep 
in  cool  place,  protected  from  sunlight,  lest  discoloration  and  odor 
develop. 


SYRUP 

Syrupus  Altha<s,  N.  F.  Each  100  mils  (Cc.)  represents  5 
Gm.  althaea,  3  mils  alcohol,  10  glycerin,  with  sugar  and  water. 
Demulcent  Vehicle.  Average  Dose:  1  fluidrachm  (4  mils 
[Cc.]). 

Syrup  Ammonium  Hypophosphite,  Squibb 

Syrupus  Ammonii  Hypophosphitis,  N.  F.  Each  fluidounce 
contains  16!/4  grains  ammonium  hypophosphite,  with  glycerin, 
compound  spirit  vanillin,  syrup  and  water.  Used  as  Expectorant 
and  Alterative.  Average  Dose  :  1  fluidrachm  (4  mils  [Cc.]). 

Syrup  Asarum  Compound,  Squibb  pint 

Syrupus  Asari  Compositus,  N.  F.;  Compound  Syrup  Canada 
Snake-root.  Each  fluidounce  represents  28J/4  grains  asarum  and 
\\/2  grains  ipecac.  Aromatic,  Stomachic.  Average  Dose:  1 
fluidrachm  (4  mils  [Cc.]). 

SYRUP  BLACKBERRY  FRUIT. 

Syrupus  Rubl  Fruclus,  N.  F.  From  fresh,  ripe  blackberries. 
Flavoring. 

Syrup  Bromides,  Squibb  pint 

Syrupus  Bromidorum,  N.  F.  Each  fluidounce  contains  about 
37'/2  grains  potassium  bromide,  37J/2  grains  sodium  bromide, 
22J/2  grams  ammonium  bromide,  I  1  5/2  grains  calcium  bromide, 
and  4  grains  lithium  bromide.  Nerve  Sedative.  Average 
Dose:  1  fluidrachm  (4  mils  [Cc.]). 

SYRUP  BUCKTHORN   BERRIES.     See  Syrup  Rhamnus  Cathartica. 


SQUIBB'S  MATERIA  MEDICA        259 

SYRUP  CALCIUM  HYDROCHLOROPHOSPHATE. 

Sjjrupus  Calcii  Hydrochlorophosphatis,  N.  F.  Each  fluidounce 
contains  about  8^/4.  grains  calcium  phosphate  rendered  soluble 
by  hydrochloric  acid,  with  tincture  lemon  peel,  syrup  and 
water.  Used  as  Anticachectic.  Average  Dose :  1  fluidrachm 
(4  mils  [Cc.]). 

SYRUP  CALCIUM  HYPOPHOSPHITE. 

Syrupus  Calc'ii  Hypophosphilis,  N.  F.  Each  fluidounce  repre- 
sents 16  grains  calcium  hypophosphite.  Used  as  Alterative 
Tonic.  Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

SYRUP  CALCIUM  IODIDE. 

Syrupus  Calcii  loJidi,  N.  F.  Each  fluidrachm  contains  about 
5  grains  calcium  iodide,  prepared  from  freshly  made  iron 
iodide  and  precipitated  calcium  carbonate.  Used  as  Alterative, 
Antisyphilitic,  Anticatarrhal.  Average  Dose:  30  minims  (2 
mils  [Cc.]). 

Syrup  Calcium  Lactophosphate,  Squibb  pint 

Syrupus  Calcii  Laclophosphatis.  Prepared  from  pure  precipi- 
tated calcium  carbonate,  lactic  acid  and  phosphoric  acid,  with 
orange-flower  water  for  flavor.  Each  fluidounce  represents  4 
grains  calcium  lactophosphate.  Bone  Nutrient,  Anticachectic. 
Average  Dose:  2J/2  fluidrachms  (10  mils  [Cc.]). 

SYRUP  CALCIUM  LACTOPHOSPHATE  WITH  IRON. 

Syrupus  Calcii  Laclophosphalis  et  Ferri,  N.  F.  Each  fluid- 
ounce  represents  about  3  grains  calcium  lactophosphate  and 
4  grains  iron  lactate.  Bone  Nutrient,  Anticachectic,  Hema- 
tinic.  Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

SYRUP  CALCIUM  AND  SODIUM  HYPOPHOSPHITES. 

Syrupus  Calcii  et  Sodii  Hypophosphilum,  N.  F.  Each  fluid- 
ounce  contains  about  16  grains  each  calcium  and  sodium  hypo- 
phosphites.  Used  as  Alterative  Tonic.  Average  Dose:  1 
fluid  achm  (4  mils  [Cc.]). 

SYRUP    CANADA    SNAKEROOT    COMPOUND.     See    Syrup    Asarum 
Compound. 

SYRUP  CIMICIFUGA  COMPOUND. 

Syrupus  CimicifugcE  Compositus,  N.  F.;  Compound  Syrup 
Black  Cohosh.  Each  fluidounce  represents  about  18  grains 
cimicifuga,  9  grains  each  licorice  and  senega,  4J/2  grains  ipecac 
and  18  grains  wild  cherry.  Used  as  Expectorant  Anticatarrhal. 
Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

The  prices  of  the  Squibb  Products  are  in  all  instances  as  low  as 
the  quality  and  quantity  of  ingredients  and  the  expense  of  man- 
ufacture allow.  They  include  containers,  packing  and  boxing.  When 
ordering  or  prescribing  medicinal  products,  specify  SQUIBB'S. 


260        SQUIBB'S  MATERIA  MEDICA 

SYRUP  CINNAMON. 

Syrupus  Cinnamomi,  N.  F.  Each  100  mils  (Cc.)  represents 
10  Cm.  Saigon  cinnamon,  5  mils  alcohol,  sugar  and  cinnamon 
water.  Aromatic  Carminative;  chiefly  Vehicle.  Average 
Dose:  1  fluidrachm  (4  mils  [Cc.]). 

SYRUP  CODEINE. 

Syrupus  Codeinat,  N.  F.  Each  fluidounce  contains  approxi- 
mately 0.9  grain  codeine  sulphate.  Cough  Sedative.  Analgesic, 
Antispasmodic.  Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

SYRUP  DOVER'S  POWDER.    See  Syrup  Ipecac  and  Opium. 

SYRUP,    EASTON'S.     See    Syrup    Iron,    Quinine    and    Strychnine 
Phosphates. 

SYRUP  ERIODICTYON  AROMATIC. 

Syrupus  Eriodlcfyi  Aromaticus,  N.  F.;  Aromatic  Syrup  Yerba 
Santa;  Syrupus  Corrigens.  Containing  fluidextract  eriodictyon, 
solution  potassium  hydroxide,  compound  tincture  cardamom, 
and  oils  sassafras,  lemon  and  cloves.  Expectorant,  but  used 
mainly  as  Vehicle  for  quinine  and  other  bitter  or  acrid  sub- 
stances. Average  Dose:  2  fluidrachms  (8  mils  [Cc.]). 

SYRUP  FIGS  COMPOUND. 

Syrupus  Ficorum  Compositus,  N.  F.  Each  100  mils  (Cc.) 
represents  30  Gm.  figs  and  20  mils  fluidextract  senna,  10  mils 
aromatic  fluidglycerate  cascara,  with  oil  fennel  and  spirit  pep- 
permint as  corrective  and  flavoring.  Laxative.  Average  Dose: 
1  fluidrachm  (4  mils). 

SYRUP  GARLIC. 

Syrupus  Allii,  N.  F.  Each  100  mils  (Cc.)  represents  20  Gm. 
garlic  extracted  with  diluted  acetic  acid,  with  syrup.  Stimu- 
lating Expectorant.  Average  Dose:  1  fluidrachm  (4  mils). 

SYRUP  GINGER. 

Syrupus  Zingiberis.  3  volume  percent,  fluidextract  ginger. 
Easily  miscible  with  water.  Aromatic  Carminative;  flavoring. 
Average  Dose:  4  fluidrachms  (15  mils  [Cc.]). 

SYRUP  GLYCYRRHIZA. 

Syrupus  Clycyrrhizte,  N.  F.;  Syrup  Licorice.  Contains  25  vol. 
percent,  fluidglycerate  glycyrrhiza.  Expectorant,  Demulcent. 
Vehicle  for  bitter  drugs.  Average  Dose:  2  fluidrachms  (8  mils 
[Cc.]). 

Syrup,  Hive  or  Croup.        See  Syrup  Squill  Compound. 

SYRUP   HYDROCHLOROPHOSPHATES.     See   Syrup   Phosphates  with 
Quinine  and  Strychnine. 


SQUIBB'S  MATERIA  MEDICA       261 

Syrup  Hypophosphites,  Squibb  pint, 

Syrupus  Hypophosphitum.  Each  fluidounce  contains  about 
20  grains  calcium  hype-phosphite,  and  7  grains  each  potassium 
and  sodium  hypophosphites,  with  5  vol.  percent,  glycerin. 
Used  as  Alterative  Tonic.  Average  Dose :  2J/2  fluidrachms  (10 
mils  [Cc.]). 

Syrup   Hypophosphites   Compound,   Clear,   Squibb 

pint, 

Syrupus  Hypophosphiium  Compositus,  N.  F.  Dropped  from 
U.  S.  P.  Each  fluidounce  contains  about  16  grains  calcium 
hypophosphite,  8  grains  each  potassium  and  sodium  hypo- 
phosphites,  1  grain  each  ferric  and  manganese  hypophosphites, 
]/2  grain  quinine  alkaloid,  and  1/20  grain  strychnine.  Used 
as  Alterative  Tonic  and  Hematinic.  Average  Dose:  2  fluid 
drachms  (8  mils  [Cc.],  after  meals,  with  water. 

Syrup  Hypophosphites  Compound,  Cloudy,  Squibb 

pint, 
Same  composition  as  preceding,  but  rendered  cloudy. 

SYRUP  IODOTANNIN. 

Syrupus  lodoiannicus,  N.  F.  Each  fluidounce  contains  about 
114  grains  iodine,  2J/2  grains  tannic  acid.  Alterative,  Resolv- 
ent. Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

©  Syrup  Ipecac,  Squibb  pint 

Sprupus  Ipecacuanha:.  Each  fluidounce  represents  about  32 
grains  ipecac.  Average  Dose:  expectorant,  15  minims  (1  mil 
[Cc.]);  emetic,  4  fluidrachms  (15  mils). 

f  SYRUP  IPECAC  AND  OPIUM. 

Syrupus  Ipecacuanha:  ei  Opii,  N.  F.;  Syrup  Dover's  Powder. 
Each  fluidounce  represents  4  grains  each  opium  and  ipecac. 
Diaphoretic,  Antispasmodic.  Average  Dose :  1  fluidrachm  (4 
mils  [Cc.]). 

SYRUP  IRON  HYPOPHOSPHITE. 

Syrupus  Fern  Hypophosphiiis,  N.  F.  Each  fluidounce  contains 
about  SVs  grains  ferric  hypophosphite,  flavored  with  orange- 
flower  water.  Hematinic,  Tonic.  Average  Dose :  1  fluidrachm 
(4  mils  [Cc.]). 

©  Syrup  Iron  Iodide,  Squibb  Ib. 

Syrupus  Ferri  lodidi.  About  5  percent,  ferrous  iodide  (nearly 
4  grains  in  each  fluidrachm).  Especially  commended  for  its 
permanence  and  reliability.  Yellowish-green  color;  sweet, 
strongly  ferruginous  taste.  Alterative,  Hematinic.  Average 
Dose:  15  minims  (1  mil  [Cc.]),  diluted.  Incompatible  with 
alkali  carbonates,  acid  salts  and  vegetable  astringents. 


jf  difficulty  is  experienced  in  procuring  any  Squibb  product, 
in  the  original  packages  here  listed,  please  notify  us;  we 
shall  see  that  your  wants  are  met  promptly  and  satisfactorily. 


262       SQUIBB'S  MATERIA  MEDICA 

SYRUP  IRON  LACTOPHOSPHATE. 

Syrupus  Ferri  Laclophosphatis,  N.  F.  Each  fluidounce  con- 
tains about  12  grains  iron  lactophosphate.  Hematinic.  Aver* 
age  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

SYRUP    IRON    OXIDE    SOLUBLE.     See    Syrup    Iron    Saccharated 
Soluble. 

SYRUP  IRON  PROTOCHLORIDE. 

Syrupus  Ferri  Prolocliloridi,  N.  F.;  Syrup  Ferrous  Chloride. 
About  8  grains  ferrous  chloride  per  fluidounce.  Hematinic. 
Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

Syrup  Iron  and  Manganese  Iodide,  Squibb  pint 

Sprupus  Ferri  el  Mangani  lodiJi,  N.  F.  Each  fluidounce  con- 
tains about  48  grains  iodide  iron  and  18  grains  iodide  man- 
ganese. Alterative,  Hematinic.  Average  Dose:  15  minims  (1 
mil  [Cc.]). 

SYRUP  IRON,  QUININE  AND  STRYCHNINE  PHOSPHATES. 

Syrupus  Ferri,  Qui'nincE  el  Slrychnince  Phosphalum,  N.  F.; 
Easton's  Syrup.  Each  fluidounce  contains  about  9  grains  ferric 
phosphate,  12  grains  quinine  as  phosphate,  and  1/n  strychnine. 
Bitter  Tonic,  Hematinic.  Average  Dose :  1  fluidrachm  (4  mils 
[Cc.]). 

SYRUP  IRON  SACCHARATED  SOLUBLE. 

Syrupus  Ferri  Saccharali  Solubilis,  N.  F.;  Syrup  Soluble  Oxide 
Iron.  Each  fluidounce  represents  about  6  grains  metallic  iron, 
in  form  of  saccharated  oxide.  Hematinic;  mainly  in  anemic 
children.  Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

SYRUP,  JACKSON'S  PECTORAL.     See  Syrup  Morphine  and  Acacia. 

SYRUP  KRAMERIA. 

Syrupus  Krameria,  N.  F.;  Syrup  Rhatany.  45  vol.  percent, 
fluidextract  krameria,  with  syrup.  Antidiarrheal.  Average 
Dose:  1  fluidrachm  (4  mils  [Cc.]). 

SYRUP  LACTUCARIUM. 

Syrupus  Lactucarii.  10  vol.  percent,  tincture  lactucanum  (1  :2), 
20  glycerin,  5  orange-flower  water.  Used  as  Cough  Seda- 
tive. Average  Dose:  2\/2  fluidrachms  (10  mils  [Cc.]). 

SYRUP  LEMON.     See  Syrup  Acid  Citric. 
SYRUP    LICORICE.     See   Syrup   Glycyrrhiza. 

SYRUP  MANNA. 

Syrupus  Mannce,  N.  F.  Each  fluidounce  repaints  57  grains 
manna.  Laxative.  Average  Dose:  2  fluidrachms  (8  mils  [Cc.]). 


SQUIBB'S  MATERIA  MEDICA        263 

SYRUP  MORPHINE  AND  ACACIA. 

Syrupus  Morphince  el  Acacia,  N.  F.;  Pectoral  Syrup;  Jack- 
son's Pectoral  (or  Cough)  Syrup.  Each  fluidounce  contains 
1/4  grain  morphine  hydrochloride,  with  mucilage  acacia  and  oil 
sassafras.  Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

Syrup  Orange,  Squibb  pint 

Syrupus  Auranlii.  5  mils  (Cc.)  tincture  sweet  orange  peel  and 
0.5  Gm.  citric  acid  in  100  mils.  Flavoring  vehicle. 

SYRUP  ORANGE  FLOWERS. 

S'yrupus  Auranlii  Florum.  Sugar  dissolved  in  orange-flower 
water.  Flavoring  vehicle. 

SYRUP,  PECTORAL.    See  Syrup  Morphine  and  Acacia. 

SYRUP  PHOSPHATES  COMPOUND. 

Syrupus  Phosphatum  Compositus,  N.  F.;  Chemical  Food.  50 
vol.  percent,  solution  phosphates  compound  with  syrup  and 
glycerin,  colored  red  with  tincture  cudbear.  Antiquated  Tonic. 
Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

SYRUP  PHOSPHATES  WITH  QUININE  AND  STRYCHNINE. 

Syrupus  Phosphatum  cum  Quinina  el  Slrychnina,  N.  F.; 
Syrup  Hydrochlorophosphates.  Each  1000  mils  (Cc.)  contains 
500  mils  solution  phosphates  compound,  4.4  Gm.  quinine  hydro- 
chloride,  0.14  Gm.  strychnine  nitrate,  with  glycerin  and  syrup. 
Used  as  General  Tonic.  Average  Dose:  1  fluidrachm  (4  mils). 

SYRUP  POPPY. 

Syrupus  Papaveris,  N.  F.  Representing  10  Gm.  poppy  capsules 
in  100  mils  (Cc.).  Mild  Opiate,  Sedative.  Average  Dose : 
1  fiuidrachm  (4  mils  [Cc.]). 

SYRUP  QUINIDINE. 

Syrupus  Quiniain<s,  N.  F.  Each  fluidounce  contains  about  15 
grains  quinidine  in  syrup  flavored  with  oil  orange.  Anti- 
periodic,  Antipyretic,  Bitter  Tonic.  Average  Dose :  1  fluid 
drachm  (4  mils  [Cc.]). 

SYRUP  RASPBERRY. 

Syrupus  Rubi  Idal,  N.  F.  From  fresh,  ripe  raspberries. 
Pleasant  Vehicle. 

SYRUP  RHAMNUS  CATHARTICA. 

Syrupus  Rhamni  Cathartics,  N.  F.;  Syrup  Buckthorn  Berries. 
20  vol.  percent,  fluidextract  buckthorn  berries,  with  oils  fennel 
and  cinnamon  as  corrigents.  Laxative.  Average  Dose :  2 
fluidrachms  (8  mils  [Cc.]). 

The  Squibb  products  are  recognized  everywhere  as  the  Quality 
Standard.  They  are  of  uniform  purity  and  strength,  hence 
therapeutically  dependable.  When  ordering  or  prescribing  med- 
icinal products,  you  will  do  well  always  to  specify  SQUIBB'S. 


264        SQUIBB'S  MATERIA  MEDICA 

SYRUP  RHUBARB. 

Sprupus    Rhei.      Each    fluidounce    represents    aboul    46    grains 
rhubarb,   and   4.6   grains   potassium   carbonate,   with   syrup   and 
spirit    cinnamon.      Laxative.      Average    Dose:    2J/2    fluidrachms 
(10  mils    [Cc.]). 
• 

©  SYRUP  RHUBARB  AROMATIC. 

Syrupus  Rhei  Aromalicus.  Each  fluidounce  contains  72  minims 
aromatic  tincture  rhubarb,  representing  about  13%  grains 
rhubarb.  Laxative.  Average  Dose:  214  fluidrachms  (10  mils 
[Cc.]). 

Syrup    Rhubarb    and    Potassa    Compound.     See    Mixture 
Rhubarb   Alkaline. 

SYRUP  ROSE. 

Syrupus  Rosa,  N.  F.  12J/4.  volume  percent,  fluidextract  rose, 
with  1  volume  percent,  dilute  sulphuric  acid.  Flavoring  vehicle. 

SYRUP  RUBUS. 

Sytrupus  Rabi,  N.  F.;  Syrup  Blackberry  Bark.  Each  fluid- 
ounce  represents  about  114  grains  blackberry  bark.  Intes- 
tinal Astringent.  Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

SYRUP  SANGUINARIA. 

Sprupus  Sanguinarice,  N.  F.;  Syrup  Bloodroot.  Each  fluid- 
ounce  represents  about  102J/2  grams  sangumana  extracted  with 
acetic  menstruum.  Expectorant.  Average  Dose :  30  minims 
(2  mils  [Cc.]). 

Syrup  Sarsaparilla  Compound,  Squibb  pint 

Syrupus  Sarsaparilla  Composiius.  20  volume  percent,  fluid- 
extract  sarsaparilla,  lj/2  fluidextract  licorice,  V/2  fluidextract 
senna,  flavored  with  oil  sassafras,  oil  anise,  and  methyl  sali- 
cylate.  Used  chiefly  as  Vehicle  for  potassium  iodide.  Aver» 
age  Dose:  4  fluidrachms  (15  mils  [Cc.]). 

SYRUP  SENEGA. 

Sjjrupus  Senega.  Each  fluidounce  represents  about  91  grains 
senega.  Expectorant.  Average  Dose :  1  fluidrachm  (4  mils 
[Cc.]). 

0  Syrup  Senna,  Squibb  pint 

Syrupus  Senna.  Each  fluidounce  represents  114  grains  senna, 
with  2.4  minims-  oil  coriander  to  flavor.  Laxative.  Average 
Dose:  1  fluidrachm  (4  mils  [Cc.]). 

SYRUP  SENNA  AROMATIC. 

Syrupus  Senna  Aromalicus,  N.  F.  Each  fluidounce  repre- 
sents 57  grains  senna,  23  grains  jalap,  and  8]^  grains 
rhubarb,  with  aromaiics.  Laxative.  Average  Dose :  2 
fluidrachms  (8  mils  [Cc.]). 


SQUIBB'S  MATERIA  MEDICA        265 

SYRUP  SENNA  COMPOUND. 

Sprupus  Senna  Composilus,  N.  F.  Each  fluidounce  represents 
about  61 J/2  grains  senna,  16'/4  grains  rhubarb  and  16'/4  grains 
frangula,  with  methyl  salicylate,  alcohol  and  syrup.  Purgative. 
Average  Dose:  2  fluidrachms  (8  mils  [Cc.]). 

SYRUP  SODIUM  HYPOPHOSPHITE. 

Syrupus  Sodii  Hypophosphilis,  N.  F.  Each  fluidounce  contains 
about  16  grains  sodium  hypophosphite.  Used  as  Alterative, 
Tonic.  Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

©  Syrup  Squill,  Squibb  pint 

Syrupus  Scills.  Each  fluidounce  represents  about  20J/2  grains 
squill  in  the  form  of  vinegar  squill.  Expectorant.  Average 
Dose:  30  minims  (2  mils  [Cc.]). 

Syrup  Squill  Compound,  Squibb  pint, 

Syrupus  Scill(E  Composilus;  Hive  or  Croup  Syrup.  Each 
fluidounce  represents  about  36J/2  grains  each  squill  and  senega  as 
fiuidextract,  and  0.9  grain  antimony  and  potassium  tartrate. 
Expectorant,  children's  Emetic.  Average  Dose:  30  minims 
(2  mils  [Cc.]) 

SYRUP  STILLINGIA  COMPOUND. 

Syrupus  Slillingice  Compositus,  N.  F.  Each  fluidounce  repre- 
sents 27J/2  grains  each  stillingia  and  corydalis,  13^4  grains 
each  iris,  sambucus  and  chimaphila,  and  7  grains  each  coriander 
and  xanthoxylum.  Used  as  Alterative.  Average  Dose:  1 
fluidrachm  (4  mils  [Cc.]). 

SYRUP  TAR. 

Sprupus  Picis  Liquids.  0.5  Gm.  tar  in  100  mils  (Cc.)  ;  or  2.3 
grains  per  fluidounce.  Expectorant.  Average  Dose:  1 
fluidrachm  (4  mils). 

©  Syrup  Tolu,  Squibb  pint 

Swupus  Tolutanus.  Each  fluidounce  contains  24  minims  tincture 
tolu.  Expectorant,  but  mainly  Vehicle.  Average  Dose:  4 
fluidrachms  (15  mils  [Cc.]). 

Syrup  White  Pine  Compound,  Squibb  pint 

Sprupus  Pini  Slrobi  Composilus,  N.  F.  The  N.  F.  IV  has 
changed  the  formula  of  this  preparation  to  the  extent  of  omitting 
the  morphine  sulphate.  Expectorant.  Average  Dose :  1  fluid 
drachm  (4  mils  [Cc.]). 


Since  we  make  only  one  quality  of  each  product,  that  best 
suited  to  the  purposes  intended,  the  specification  "Squibb's" 
is  not  open  to  various  interpretations,  but  has  a  plain,  positive 
meaning.  When  ordering  or  prescribing,  specify  SQUIBB'S. 


266       SQUIBB'S  MATERIA  MEDICA 

Syrup  White  Pine  Compound  with  Morphine,  Squibb 

pint 

Syrupus  Pini  Slrobi  Composilus  cum  Morphina,  N.  F.  Each 
fluildounce  represents  about  39  grains  each  white  pine  bark  and 
wild  cherry,  4.6  grains  each  aralia  and  balsam  poplar  buds, 
3.7  grains  sanguinaria,  3.2  grains  sassafras,  about  1/5  grain 
morphine  sulphate,  and  3  minims  chloroform.  Expectorant;  in 
long-standing  coughs  after  grippe,  etc.  Average  Dose:  30  min- 
ims (2  mils  [Cc.j). 

Syrup  White  Pine  Compound  with  Morphine  and  Tar, 
Squibb  pint 

Preceding   product,   with   addition   of   tar. 

Syrup  White  Pine  Compound  with  Tar,  Squibb    pint 
Syrup  White  Pine  Compound,  with  addition  of  tar. 

0  Syrup  Wild  Cherry,  Squibb  pint 

Syrupus  Pruni  Virginiance.  Prepared  by  water  and  glycerin 
percolation  of  "wild  cherry  and  solution  of  sugar.  The  full 
medicinal  value  of  the  wild  cherry  is  thus  retained.  Cough 
Sedative,  but  mainly  Vehicle.  Average  Dose :  1  fluidrachm  (4 
mils  [Cc.]). 

SYRUP  YERBA  SANTA  AROMATIC.    See  Syrup  Eriodictyon  Aromatic. 

Talcum  Powder,  Squibb  sprinkler-top  cans,  per  doz. 

A  hygienic  toilet  powder  specially  prepared  for  the  dressing 
room  and  nursery.  Non-irritating  and  absorbent.  This  powder 
is  made  in  response  to  many  requests  received  by  us  from  physi- 
cians who  have  felt  the  need  for  a  pure  product  of  correct 
composition.  The  talcum  powders  of  the  market  are  often 
harmful  because  they  contain  impurities,  or  souring  perfume 
oils,  all  of  which  are  injurious.  Squibb's  Talcum  Powder  is 
made  from  best  selected  talcum,  carefully  prepared  in  im- 
palpable powder  form.  It  is  guaranteed  to  be  free  from  starch, 
chalk  and  other  foreign  substances,  and  may  therefore  be 
used  freely  even  on  the  most  sensitive  skin.  Supplied  in  Carna- 
tion and  Violet  odors,  and  Unscenled. 

Talcum  Purified,  Squibb 

*Fine  Powder,  for  Dusting  tin,  lb. 

Coarse  Powder,  for  Filtering  tin,  Ib. 

Talcum  Purificalum.  Purified,  native,  hydrous  magnesium  sili- 
cate, freed  from  soluble  matter  by  boiling  in  acidulated  water. 

TAMARIND. 

TamarinJus,  N.  F.  Preserved  pulp  of  fruit  of  Tamarindus 
indica  (Fam.  Leguminosa) .  Reddish-brown  to  dark-brown, 
pulpy  mass.  Distinct  odor;  sweet,  agreeably  acid  taste.  Mild 
Laxative.  Average  Dose:  4  drachms  (15  Gm.). 


SQUIBB'S  MATERIA  MEDICA       267 

©  TANNALBIN. 

Tannin  Albuminate  Exsiccated.  Light-brown,  odorless,  taste- 
less, powder;  50  percent,  tannic  acid.  Insoluble  in  ordinary  sol- 
vents. Intestinal  Astringent.  Dose:  15  to 30  grains  (1  to  2  Gm.). 

TAKNI&EN. 

Acetyltannin.  Light-gray,  nearly  odorless  and  tasteless,  slightly 
hygroscopic  powder.  Soluble  in  alcohol;  insoluble  in  water. 
Intestinal  Astringent.  Dose:  8  to  15  grains  (0.5  to  1  Gm.). 

Tannin.        See  Acid  Tannic. 

TANNOFORM. 

Tannin-formaldehyde.  CHoCC^HgOg^.  Condensation 
product  of  tannic  acid  and  formaldehyde.  Whitish-red,  odor- 
less powder.  Soluble  in  alcohol,  ammonia,  alkalies;  insol- 
uble in  water.  Drying  Antiseptic  and  Deodorant;  Intestinal 
Astringent  and  Disinfectant.  Externally  pure  or  as  10  to  25 
percent,  dusting  powder.  Dose:  4  to  15  grains  (0.25  to  1  Gm.). 

TANNOPIN. 

Hexamethylenetetraminetannin ;'  Tannon.  (CH2)6N4.(Ci4- 
HioOg),3.  Fawn-colored,  odorless,  tasteless  powder.  87  per- 
cent, tannic  acid;  13  percent,  hexamethylenamine.  Insoluble  in 
ordinary  solvents;  soluble  with  decomposition  in  dilute  alkalies. 
Intestinal  Astringent  and  Disinfectant.  Dose:  8  to  15  grains 
(0.5  to  1  Gm.),  4  times  daily. 

©TAR. 

Fix  Liquida;  Pine  Tar.  Obtained  by  destructive  distillation  of 
wood  of  Pinus  paluslris  or  other  species  of  Pinus  (Fam. 
Pinacea).  Miscible  with  alcohol,  ether,  chloroform,  oils; 
slightly  soluble  in  water.  Antiseptic,  Anticatarrhal,  Expec- 
torant; used  mainly  topically,  in  skin  diseases.  Average  Dose: 
8  grains  (0.5  Gm.).  (See  also  Wine.) 

TARAXACUM. 

Taraxacum;  Dandelion.  Dried  rhizome  and  roots  of  Taraxa- 
cum officinale  (Fam.  Composites).  Odorless;  taste  bitter.  Bit- 
ter Tonic,  Mild  Laxative.  Average  Dose:  12.0  grains  (8  Gm.). 
(See  also  Elixir;  Extract;  Fluidextract.) 

Tartar   Emetic.         See  Antimony  and   Potassium  Tartrate. 
Tartar,  Soluble.  See  Potassium  Tartrate 

TEA,  BREAST.     See  Species  Pectoral. 
TEA,  LAXATIVE.     See  Species,  Laxative. 
TEA,  ST.  GERMAIN.     See  Species,  Laxative. 


The  founder  of  the  House  of  Squibb,  Dr.  Edward  R.  Squibb, 
not  only  had  high  ideals,  but  lived  and  labored  for  them;  and, 
in  the  words  of  William  Miller  Bartlett,  "the  House  of  Squibb 
stands  today  as  a  living  monument  to  the  honor,  integrity,  zeal 
and  devotion  of  its  founder." 


268       SQUIBB'S.MATERIA  MEDICA 

TEREBENE. 

Terebenum.  A  liquid  consisting  of  dipentene  and  other  hydro- 
carbons produce'd  by  action  of  concentrated  sulphuric  acid 
on  oil  turpentine.  Nearly  colorless;  agreeable,  thyme-like 
odor;  aromatic,  slightly  terebinthinate  taste.  Sp.  gr.  0.860  to 
0.865.  I  Gm.  dissolves  in  3  mils  (Cc.)  alcohol ;  slightly  soluble  in 
water.  Expectorant,  like  oil  turpentine;  in  chronic  coughs 
chiefly.  Average  Dose:  4  minims  (0.25  mil  [Cc.]).  Terebene 
becomes  resinified  on  exposure,  turns  yellow,  and  acquires 
an  acid  reaction. 

0  Terpin  Hydrate,  Squibb 

*CrystaIs  carton,  Ib.          ;  %  Ib.          ;  bottle,  oz. 

Powdered  carton,  Ib.          ;  '/£  Ib.          ;  bottle,  oz. 

Terplni  Hydras.  QoHooOo.HoO.  Hydrate  of  the  dihydroxy- 
alcohol  terpin.  Colorless,  lustrous,  rhombic  prisms;  or  white 
powder.  Nearly  odorless;  slightly  aromatic,  faintly  bitter 
taste.  1  Gm.  dissolves  in  about  200  mils  (Cc.)  water,  13  al- 
cohol, 135  chloroform,  140  ether.  Expectorant,  Antiseptic, 
Diuretic.  Average  Dose :  4  grains  (0.25  Gm.) ;  as  diuretic, 
10  to  15  grains  .(0.65  to  1  Gm.). 

Test   Solutions.        See  under  Reagents   (Part  IV). 

Test    for    Occult    Blood.      See    Tablets    Occult    Blood    Test, 
Part  II  of  this  book. 

Theine.         See  Caffeine. 

0  Theobromine,  Squibb  bottle,  oz.        ;  J/s-oz. 

Dimethylxanthine.  CyHsOoN-i.  Alkaloid  from  Theobroma 
Cacao  (Fam.  Sierculiacea).  White,  very  bitter  powder.  Sol- 
uble in  ether;  sparingly  in  water,  alcohol,  chloroform.  Diu- 
retic, in  cardiac  dropsy.  Dose:  5  to  15  grains  (0.3  to  1  Gm.). 

0  Theobromine  Sodio=Salicylate,  Squibb 

bottle,  oz.          ;  Vg-oz. 

Theobromincs  Sodio-Salic.ylas.  Sodium-Theobromine  and 
Sodium  Salicylate  in  approximately  molecular  proportions. 
Yields  not  less  than  46.5  percent,  theobromine.  Fine,  white, 
odorless  powder;  sweetish,  saline  taste.  1  Gm.  dissolves  in 
1  mil  (Cc.)  water;  slightly,  soluble  in  alcohol.  On  exposure 
it  decomposes  and  becomes  less  soluble.  Incompatible  with 
acids,  acid  syrups,  bicarbonates,  ferric  and  quinine  salts,  in 
solution.  Diuretic.  Average  Dose:  15  grains  (I  Gm.). 

THEOCIN.     Brand  of  Theophylline. 


SQUIBB'S  MATERIA  MEDICA        269 

THEOPHYLLINE. 

Theophyllina.  Organic  base  isomeric  with  theobromin*;  ob- 
tained from  tea  and  also  synthetically.  CrHgC^N^HoO. 
White,  odorless,  bitter  powder.  1  Cm.  dissolves  in  100  mils 
(Cc.)  water,  80  alcohol;  sparingly  soluble  in  ether.  Forms  salts 
with  alkalies.  Diuretic,  like  theobromine;  more  powerful,  but 
not  so  lasting.  Average  Dose:  4  grains  (0.25  Gm.),  in  warm 
tea. 

THIGENOL. 

Solution  Sodium  Sulpholeate.  Contains  2.85  percent,  sulphur. 
Dark-brown,  thick  liquid,  of  slight  sulphidic  odor.  Soluble 
freely  in  water,  diluted  alcohol,  glycerin,  chloroform,  oils. 
Incompatible  with  mineral  acids.  Alterative,  Anticatarrhal, 
Antiphlogistic,  similar  in  use  to  ichthyol.  Dose :  3  to  10  grains 
(0.2  to  0.65  Gm.).  Externally  in  all  strengths. 

Thiosinamine,  Squibb  bottle, oz. 

Allyl  Sulphocarbamide;  Rhodalline.  CsHs.CHa^S.  Color- 
less, rhombic  crystals;  garlic  odor;  bitter  taste.  Moderately 
soluble  in  water;  readily  in  alcohol  and  ether.  Sodium  or 
potassium  salicylate  increases  aqueous  solubility.  Resolvent, 
Discutient.  Used  internally,  or  hypodermically  (in  10  percent, 
glycerin-aqueous  or  hydroalcoholic  solution),  in  stricture,  corneal 
opacity,  deafness,  etc.;  externally  in  lupus,  scars,  glandular 
tumors,  etc.  Dose:  J/2  to  1J/2  grains  (0.03  to  0.1  Gm.),  two 
or  three  times  daily  by  mouth;  twice  a  week  subcutaneously,  in 
1-5  percent,  alcoholic  or  10  percent,  glycerinated  water  solu- 
tion. A  15  percent,  aqueous  solution  can  be  prepared  with 
aid  of  7J/2  percent,  antipyrine.  Incompatible  with  water  alone, 
which  decomposes  it,  but  this  change  is  to  a  limited  extent 
prevented  by  the  presence  of  glycerin. 

THOMPSONIAN  NUMBER  Six.    See  Tincture  Capsicum  and  Myrrh. 
THOMPSON'S  SOLUTION  PHOSPHORUS.     See  Solution  Phosphorus. 
THORNAPPLE.     See  Stramonium. 
THOROUGHWORT.    See  Eupatorium. 

THUJA. 

Thuja,  N.  F.;  Arbor  Vitae.  Recently  dried,  leafy  young 
twigs  of  Thuja  occidenlalis  (Fam.  Pinaceae).  Strongly 
balsamic,  aromatic  odor;  camphoraceous,  bitter  taste.  Used  as 
Febrifuge,  Expectorant,  Anthelmintic;  indications  not  well  de- 
fined. Average  Dose:  30  grains  (2  Gm.). 

The  Squibb  Ideals  have  taken  concrete  form  in  the  Squibb 
Products;  these  are  universally  recognized  as  standards  of 
uniform  Purity  and  Efficacy,  that  is,  general  Excellence  and 
Reliability.  Specify  SQUIBB'S  when  prescribing  or  ordering. 


270       SQUIBB'S  MATERIA  MEDICA 

THYME. 

Thymus,  N.  F.  Dried  tops  of  Thymus  vu/gan's  (Fam.  Labia- 
/<E).  Agreeable,  aromatic  odor;  aromatic,  warming  taste. 
Rubefacient;  Aromatic,  Carminative.  Average  Dose:  60  grains 
(4  Cm.). 

0  Thymol,  Squibb  bottle,  oz. 

Thymol;  Thyme  Camphor.  CioHi4O.  Natural,  volatile 
phenol  occurring  in  oil  Thymus  Vulgaris  (Thyme)  and  some 
other  volatile  oils.  Large,  colorless,  translucent  prisms;  thyme- 
like  odor;  pungent,  aromatic  taste.  1  Gm.  dissolves  in  1010  mils 
(Cc.)  water,  1  alcohol,  0.7  chloroform,  1.5  ether,  1.7  olive 
oil.  Antiseptic,  Anthelmintic.  Average  Dose:  antiseptic,  2  grains 
(0.13  Gm.)  ;  anthelmintic,  15  grains  (1  Gm.)  per  day.  When 
triturated  with  about  equal  part  camphor,  menthol,  chloral 
hydrate,  antipyrine,  carbolic  acid,  quinine  sulphate,  salol,  or 
urethane,  it  liquefies. 

©  Thymol  Iodide,  Squibb  bottle,  oz. 

Thymolis  loJidum;  Dithymol  Diiodide.  CooHo-iOo^.  Red- 
dish-brown or  reddish-yellow,  bulky  powder;  faint  aromatic 
odor;  not  less  than  43  percent,  iodine.  Soluble  readily  in 
ether,  chloroform,  collodion  and  oils;  slightly  in  alcohol;  in- 
soluble in  water  or  glycerin.  Wound  antiseptic  like  iodoform, 
used  like  latter.  In  making  solutions,  avoid  heat  and  dispense 
in  dark-amber  vials. 

THYREOIDECTIN. 

Dried  blood  of  thyroidectomied  animals.  Coarse,  reddish-brown 
powder.  Used  mainly  in  Basedow's  disease.  Dose:  5  to  10 
grains  (0.3  to  0.65  Gm.),  in  capsules. 

©Thyroids  Dried,  Squibb  bottle, oz. 

Thyroideum  Siccum.  Thyroid  glands  of  animals  used  for  food 
by  man,  freed  from  connective  tissue  and  fat,  cleaned,  dried 
and  powdered.  Yellowish  powder;  slight  odor;  I  Gm.  repre- 
sents about  5  Gm.  fresh  gland  and  contains  about  0.2  percent, 
iodine.  Alterative,  Anticachectic ;  in  myxedema,  obesity,  struma, 
etc.  Average  Dose:  lj/2  grains  (0.1  Gm.). 

THYROIODINE.     See  lodothyrine. 

Tin   (Mossy)   Reagent.       See  Reagents  (Part  IV). 


TINCTURES. 

Squibb's  Tinctures  are  made  from  the  best  quality  of 
crude  drug  obtainable,  no  drug  being  accepted  that  does 
not  fully  come  up  to  the  high  standard  set  for  it  by  the 
Squibb  Laboratories,  which  in  many  instances  is  consider- 
ably above  the  maximum  pharmacopoeia!  requirements; 


SQUIBB'S  MATERIA  MEDICA        271 

and  such  as  contain  definite  proximate  principles  are  care- 
fully assayed  and  standardized  to  the  U.  S.  P.  require- 
ments. In  addition,  the  potent  tinctures  for  which  the 
U.  S.  P.  demands  or  recommends  physiological  assays, 
are  assayed  by  the  methods  therein  outlined. 

0  Tincture  Aconite  Root,  Squibb         pint        ;  14  P>n* 

Tinclura  Aconili.  Assays  0.045  to  0.055  Gm.  ether-soluble 
alkaloids  in  100  mils  (Cc.).  Also  physiologically  tested;  min- 
imum lethal  dose  not  greater  than  0.0004  mil  per  Gm.  weight  of 
guinea-pig.  Antipyretic,  Circulatory  Sedative,  Analgesic, 
Average  Dose:  5  minims  (0.3  mil).  Acts  within  15  minutes, 
and  is  eliminated  within  3  hours.  Antidotes:  emetics;  atropine, 
digitalis  or  ammonia;  small,  frequent  doses  of  stimulants;  arti- 
ficial respiration. 

Tincture  Aloes,  Squibb  pint         ;  14  pint 

Tinctura  Aloes.  10  Gm.  aloes  and  20  Gm.  licorice  in  100  mils 
(Cc.).  Cathartic;  acts  mostly  on  large  intestines.  Average 
Dose:  30  minims  (2  mils). 

Tincture  Aloes  and  Myrrh,  Squibb 

pint          ;  14  pint 

Tinciura  Aloes  el  Myrrhce,  N.  F. ;  Elixir  Proprietatis  Paracelsi. 
Contains  10  Gm.  each  aloes,  myrrh  and  licorice,  in  100  mils 
(Cc.).  Cathartic.  Average  Dose:  30  minims  (2  mils).  In- 
compatible with  water. 

Tincture  Antiperiodic,  Squibb 

*With  Aloes  pint          ;  14  pint 

Without  Aloes  pint          ;  14  pint 

Tinctura  Antiperiodica,  N.  F.;   Warburg's  Tincture. 

(1)  With  Aloes.    Made  from  extract  aloes  175  Gm.  in  100  mils 
[Cc.]),  rhubarb,   angelica,  elecampane,  saffron,  fennel,  gentian, 
zedoary,    cubeb,    myrrh,    white    agaric,    camphor,    black    pepper, 
cinnamon,    ginger,    quinine    bisulphate    (9    grains    per    fl.    oz.). 
Dose:   I    to  4  fluidrachms   (4  to  16  mils). 

(2)  Without  Aloes.     Like  preceding,  but  without  extract  aloes. 

Tincture  Arnica  Flowers,  Squibb          pint         ;  14  P'nt. 

Tinctura  Arnicce.  20  Gm.  arnica  flowers  in  100  mils  (Cc.). 
Mild  Rubefacient;  rarely  used  internally,  as  Febrifuge  and 
Alterative.  Average  Dose:  15  minims  (1  mil). 


The  Squibb  Label  on  a  package  is  a  positive  guaranty  for  the 
uniform  Purity  and  Reliability  of  the  product.  We  make  only 
ONE  quality:  the  SQUIBB  quality;  and  our  prices  are  as  low 
as  they  can  be  made  for  that  quality.  Specify  SQUIBB'S. 


272        SQUIBB'S  MATERIA  MEDICA 

TINCTURE  AROMATIC. 

Tinclura  Aromalica,  N.  F.  Representing  cinnamon,  ginger, 
galangal,  cloves  and  cardamom.  Aromatic,  Carminative. 
Average  Dose:  30  minims  (2  mils  [Cc.]). 

Tincture  Asafetida,  Squibb  pint        ;  |4p>nt 

Tinclura  Asaf&liJce.  Representing  20  Gm.  in  100  mils  (Cc.). 
Used  as  Nerve  Sedative,  Carminative.  Average  Dose:  15 
minims  (1  mil). 

®  Tincture  Belladonna  Leaves,  Squibb 

pint          ;  ]/4  pint 

Tinctura  Belladonnas  Foliorum.  Assays  0.027  to  0.033  Gm. 
alkaloids  in  100  mils  (Cc.).  Anodyne,  Antispasmodic,  Anti- 
hydrotic.  Average  Dose:  12  minims  (0.75  mil).  Antidotes: 
tannin,  then  emetics;  morphine;  pilocarpine,  physostigmine,  or 
aconitine,  hypodermically. 

Tincture    Benzoin,    Squibb  pint         ;  '/4  pint 

Tinctura  Benzoini.  20  Gm.  in  100  mils  (Cc.).  Vulnerary; 
rarely  Expectorant  and  Anticatarrhal.  Average  Dose:  15  min- 
ims (1  mil).  Incompatible  with  water. 

©  Tincture  Benzoin  Compound,  Squibb 

pint          ;  ]/4  pint 

Tinctura  Benzoini  Composita;  Friars's  or  Turlington's  Balsam. 
10  Gm.  benzoin,  2  Gm.  aloes,  8  Gm.  storax  and  4  Gm.  balsam 
tolu,  in  100  mils  (Cc.).  Anticatarrhal,  Vulnerary.  Average 
Dose:  30  minims  (2  mils). 

TINCTURE,  BESTUSCHEFF'S.    See  Tincture  Iron  Chloride,  Ethereal. 

TINCTURE,  BITTER. 

Tinclura  Amara,  N.  F.;  Stomachic  Tincture;  Bitter  Stomach 
Drops.  Representing  gentian,  centaury,  bitter  orang«  peel,  and 
zedoary.  Average  Dose:  30  minims  (2  mils  [Cc.]). 

TINCTURE    BITTER    ORANGE    PEEL.     See   Tincture   Orange    Peel 
Bitter. 

Tincture  Bryonia,  Squibb  pint        ;  J4   P>nl 

Tinclura  Bryonice,  N.  F.  10  Gm.  bryonia  root  in  100  mils 
(Cc.).  Hydragogu*  Cathartic,  Alterative.  Average  Dose:  1 
fluidrachm  (4  mils  [Cc.]). 

TINCTURE  CACTUS  GRANDIFLORUS. 

Tinctura  Cacti  Crandiflori,  N.  F.  50  Gm.  drug  to  100  mils 
(Cc.) ;  mentsruum,  pure  alcohol.  Used  as  Cardiac  Stimulant; 
value  doubted  by  many.  Average  Dose:  15  minims  (1  mil). 

Tincture  Calabar  Bean.          See  Tincture  Physostigma. 

TINCTURE  CALENDULA. 

Tinclura  Calendula,  N.  F. ;  Tincture  Marigold.  20  Gm.  in 
100  mils  (Cc.).  Mild  Counter-irritant,  Discutient. 


SQUIBB'S  MATERIA  MEDICA       273 

Tincture  Calumba,  Squibb  pint         ;  14  pint, 

Tinctura  Calumbee;  Tincture  Colombo.  20  Gm.  in  100  mils 
(Cc.).  Bitter  Tonic,  Stomachic.  Average  Dose:  1  fluidrachm 
(4  mils). 

Tincture   Cannabis,   Squibb  pint         ;  %  pint 

Tinctura  Cannabis.  Represents  10  Gm.  cannabis  in  each  100 
mils  (Cc.).  Physiologically  assayed  by  U.  S.  P.  method; 
incoordination  produced  by  0.3  mil  per  kilo  weight  of  dog. 
Antispasmodic,  Sedative.  Average  Dose:  12  minims  (0.75 
mil).  Incompatible  with  water.  Antidotes:  emetics;  atropine, 
strychnine,  or  caffeine  hypodermically ;  strong  coffee. 

®  Tincture  Cantharides,  Squibb         pint,         ;  %  pint 

Of  drug  strength  of  U.  S.  P.  Tinctura  C antharidis ;  Tincture 
Spanish  Flies,  (10  Gm.  in  100  mils  [Cc.]),  but  made  by  a 
different  process  which  extracts  the  drug  more  satisfactorily  and 
thus  yields  a  tincture  of  greater  activity.  Counter-irritant  and 
Hairgrowth  Stimulant;  Genito-urinary  Stimulant.  Average  Dose : 
1*/2  minims  (0.1  mil),  well  diluted.  Antidotes:  emetics;  flaxseed 
tea;  morphine  subcutaneously ;  opium  by  rectum.  Avoid  oils. 

@  Tincture  Capsicum,  Squibb  pint         ;  J4  Pmt 

Tinctura  Capsici;  Tincture  Cayenne  Pepper.  10  Gm.  in  100 
mils  (Cc.).  Rubefacient,  Carminative,  Stomachic.  Average 
Dose:  8  minims  (0.5  mil),  diluted. 

TINCTURE  CAPSICUM  AND   MYRRH. 

Tinctura  Capsici  et  Myrrhs,  N.  F.;  Hot  Drops;  Thompsonian 
Numbei  Six.  I  fluidounce  represents  about  14  grains  capsi- 
cum and  55  grains  myrrh.  Carminative,  Stomachic.  Average 
Dose:  30  minims  (2  mils  [Cc.]),  in  sweetened  water. 

TINCTURE  CARAMEL. 

Tinclura  Caramellis,  N.  F.  10  Gm.  caramel  in  100  mils  (Cc.). 
Brown  coloring  for  liquids. 

®  Tincture  Cardamom,  Squibb  pint         ;  ]/4  pint 

Tinctura  Cardamomi.  15  Gm.  in  100  mils  (Cc.),  as  against 
20  Gm.  in  U.  S.  P.  Vlllth  Rev.  Carminative,  Corrective, 
Aromatic.  Average  Dose:  30  minims  (2  mils). 

Tincture  Cardamom  Compound,  Squibb 

pint         ;  1/4  pint 

Tinclura  Cardamomi  Composita.  20  Gm.  cardamom,  25  Gm. 
Saigon  cinnamon,  12  Gm.  caraway,  5  Gm.  cochineal,  together  with 
glycerin  and  diluted  alcohol  to  make  1000  mils  (Cc.).  Aromatic 
Carminative,  Stomachic.  Average  Dose:  1  fluidrachm  (4  mils). 


This  house  supplies  only  one  quality  of  each  product:  that  best 
suited  to  the  purposes  intended.  The  specification  "Squibb's" 
is  not  open  to  various  interpretations;  it  has  a  plain,  posi- 
tive meaning.  Therefore,  when  prescribing,  specify  SQUIBB'S. 


274        SQUIBB'S  MATERIA  MEDICA 

Tincture  Catechu   Compound.     See  Tincture  Gambir  Com- 
pound. 

Tincture    Cimicifuga,    Squibb  pint         ;  !  4  pint 

Tinctura  Cimicifuga,  N.  F. ;  Tincture  Black  Cohosh.  Dropped 
from  U.  S.  P.  20  Gm.  in  100  mils  (Cc.).  Used  as  Alter- 
ative, Sedative,  Emmenagogue;  in  rheumatism,  chorea,  dys- 
menorrhea,  etc.  Average  Dose:  1  fluidrachm  (4  mils). 

©  Tincture  Cinchona,  Squibb  pint         ;  %  pint 

Tinctura    Cinchona.     Assays  0.8   to    1  Gm.    alkaloids   in    100 

mils  (Cc.).  Astringent  Bitter  Tonic.  Average  Dose:  1  fluid 
drachm  (4  mils). 

Tincture  Cinchona  Compound,  Squibb 

pint         ;  14  pint 

Tinctura  Cinchona  Composite.  100  mils  (Cc.)  represent  10 
Gm.  red  cinchona,  8  Gm.  bitter-orange  peel,  and  2  Gm.  ser- 
pentaria.  Assays  0.4  to  0.5  Gm.  alkaloids  in  each  100  mils 
(Cc.).  Aromatic  Astringent  Bitter.  Average  Dose:  1  fluid 
drachm  (4  mils). 

TINCTURE  CINNAMON. 

Tinctura  Cinnamomi.  20  Gm.  Saigon  cinnamon,  and  7.5  Gm. 
glycerin  in  100  mils  (Cc.).  Carminative,  Antidiarrheal. 
Average  Dose:  30  minims  (2  mils). 

TINCTURE  COCCULUS  INDICUS. 

Tinclura  Cocculi  Indici,  N.  F. ;  Tincture  Fish  Berries.  10 
Gm.  drug  to  100  mils  (Cc.) ;  menstruum,  diluted  alcohol. 
External  Parasiticide.  Antidotes:  none  known.  It  is  advised 
to  give  emetics,  copious  draughts  of  warm  water  and  to  treat 
symptoms  as  they  arise. 

©  Tincture  Colchicum  Seed,  Squibb        pint      ;  %  pint 
Tinctura  Colchici  Seminis,     Assays  0.036  to  0.044  Gm.  colchi- 
cine  in    100  mils    (Cc.).    Antipodagric,  Antineuralgic.   Average 
Dose:  30  minims  (2  mils). 

TINCTURE  COTO.     See  Tincture  Paracoto. 

TINCTURE  CUBES. 

Tinctura  Cubebce,  N.  F.  20  Gm.  Cubeb  in  100  mils  (Cc.) 
Carminative,  Expectorant.  Genito-urmary  Anticatarrhal.  Aver* 
age  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

Tincture  Cudbear,   Squibb  pint         ;  14  P'nt 

Tinclura  Persionis,  N.  F.  Coloring-agent  where  a  bright-red 
tint  is  desired,  particularly  in  acid  liquids. 

Tincture  Cudbear  Compound,  Squibb 

pint          ;  14  pin' 

Tinctura  Persionis  Composita,  N.  F.  Contains  cudbear  and 
caramel.  Brownish-red  coloring  agent. 


SQUIBB'S  MATERIA  MEDICA       275 

TINCTURE  DELPHINIUM.    See  Tincture  Larkspur. 

©  Tincture  Digitalis,  Squibb  pint        ;  14  pint 

Tlnclura  Digitalis.  10  Gm.  digitalis  in  100  mils  (Cc.). 
Physiologically  assayed  according  to  U.  S,  P.  and  standard- 
ized; minimum  lethal  dose  not  more  than  0.006  mil  (Cc.)  per 
Gm.  weight  of  frog.  Also  assayed  biologically  by  "Cat  Meth- 
od" of  Dr.  Hatcher.  Cardiac  Stimulant,  Diuretic;  in  cardiac 
decompensation;  most  effective  when  heart  action  is  rapid  and 
very  irregular;  effective  in  edema  only  when  latter  is  due 
to  impaired  circulation.  Average  Dose:  8  minims  (0.5  mil). 
Very  slowly  absorbed  and  eliminated.  Shows  no  positive  effect 
on  circulation  within  36  or  48  hours  and  no  diuretic  influence 
within  72  hours.  Antidotes:  tannin,  emetics;  nitroglycerin, 
strychnine  or  alcohol;  morphine;  rest  in  horizontal  position. 

Tincture  Digitalis  Fat=Free,  Squibb 

pint         ;  |/4  pint         ;  oz. 

From  digitalis  leaves  deprived  of  their  fat  by  a  process  which 
does  not  destroy  or  remove  any  proximate  principles.  Phys- 
iologically assayed  and  standardized  by  "Cat  Method"  of 
Hatcher;  each  mil  (Cc.)  represents  1  cat  unit.  Direct  Cardiac 
Stimulant,  Diuretic.  Average  Dose:  8  minims  (0.5  mil). 

Tincture   Dover's   Powder.    See  Tincture  Ipecac  and  Opium. 

TINCTURE  ERGOT  AMMONIATED. 

Tinclura  Ergolce  Ammoniala,  N.  F.  25  Gm.  drug  in  100  mils 
(Cc.).  Menstruum,  ammonia  water  (10%),  alcohol  and 
water.  Vasoconstrictor,  Parturient.  Average  Dose:  1  fluid 
drachm  (4  mils). 

TINCTURE  FERRATED  EXTRACT  APPLES. 

Tinclura  Ferri  Pomala,  N.  F. ;  Tincture  Iron  Malate  (Crude). 
10  Gm.  ferrated  extract  apples,  10  mils  (Cc.)  alcohol,  80 
mils  cinnamon  water.  Mild  Hematinic.  Average  Dose:  1 
fluidrachm  (4  mils),  containing  about  |/g  grain  metallic  iron. 

Tincture  Gambir  Compound,  Squibb      pint        ;  |4  P"11 
Tinclura  Gambir  Composite.     5  Gm.  gambir  and  2.5  Gm.  Sai- 
gon cinnamon  in    100  mils   (Cc.).      Intestinal  and  External  As- 
tringent.    Average  Dose:   1    fluidrachm   (4  mils). 

Tincture  Qelsemium,  Squibb  pint         ;  %  pint 

Tinclura  Celsemii;  Tincture  Yellow  Jasmine.  10  Gm.  drug 
in  100  mils  (Cc.)  ;  assays  about  0.03  Gm.  alkaloids  in  100  mils. 
Antineuralgic,  Antispasmodic,  Nerve  Sedative.  Average  Dose: 
4  minims  (0.25  mil).  Antidotes:  emetics;  atropine  or  strophan- 
thin  subcutaneously ;  stimulants. 


The  prices  of  the  Squibb  Products  are  irt  alf  instances  as  low  as 
the  quality  and  quantity  of  ingredients  and  the  expense  of  man- 
ufacture allow.  They  include  containers,  packing  and  boxing.  When 
ordering  or  prescribing  medicinal  products,  specify  SQUIBB'S. 


276       SQUIBB'S  MATERIA  MEDICA 

0  Tincture  Gentian  Compound,  Squibb 

pint         ;  ]/4  pint 

Tinctura  Gentiance  Composita.  10  Gm.  gentian,  4  Gm.  bitter- 
orange  peel  and  1  Gm.  cardamom,  in  100  mils  (Cc.).  Bitter 
Tonic,  Stomachic.  Average  Dose:  1  fluidrachm  (4  mils). 

0  Tincture  Ginger,  Squibb  pint         ;  |4  P>nt 

Tinctura  Zingiberis.  20  Gm.  in  100  mils  (Cc.).  Made  from 
best  Jamaica  ginger  obtainable.  Aromatic  Carminative,  Gastro- 
intestinal Stimulant.  'Average  Dose:  30  minims  (2  mils). 

Tincture  Golden   Seal.     See  Tincture  Hydrastis. 
Tincture  Green  Soap.      See  Liniment  Soap  Soft. 

Tincture  Guaiac,  Squibb  pint         ;  |4  P'nt 

Tinctura  Cuaiaci.  20  Gm.  guaiac  in  100  mils  (Cc.).  Altera- 
tive ;  in  chronic  rheumatism,  gout,  etc.  Average  Dose :  1 
fluidrachm  (4  mils).  Incompatible  with  water. 

Tincture  Guaiac  Ammoniated,  Squibb 

pint          ;  }/4  pint 

Tinclura  Cuaiaci  Ammoniata.  20  Gm.  guaiac  with  aromatic 
spirit  ammonia  to  produce  100  mils  (Cc.).  Alterative,  Em- 
menagogue.  Average  Dose:  30  minims  (2  mils).  Incompatible 
with  water. 

TINCTURE  GUAIAC  COMPOUND. 

Tinclura  Cuaiaci  Composita,  N.  F.;  Dewees's  Tincture  of 
Guaiac.  Each  fluidounce  represents  about  57  grains  guaiac,  23/4 
grains  potassium  carbonate  and  14.6  grains  pimenta.  Alterative, 
Emmenagogue.  Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

Tincture  Henbane.     See  Tincture  Hyocyamus. 

TINCTURE  HOPS. 

Tinctura  Humuli,  N.  F.  20  Gm.  hops  in  100  mils  (Cc.). 
Bitter  Stomachic.  Average  Dose:  1  fluidrachm  (4  mils). 

Tincture  Hydrastis,  Squibb  pint         ;  |/4  pint 

Tinclura  Hydraslis;  Tincture  Golden  Seal.  Assays  0.36  to  0.44 
Gm.  ether-soluble  alkaloids  in  100  mils  (Cc.).  Bitter  Tonic. 
Astringent,  Alterative.  Average  Dose:  1  fluidrachm  (4  mils). 

©  Tincture   Hyoscyamus,  Squibb         pint         ;  %  pint 

Tinctura  Hyoscyami;  Tincture  Henbane.  Assays  0.0055  to 
0.0075  Gm.  alkaloids  in  100  mils  (Cc.).  Sedative,  Antispas- 
modic,  Anodyne.  Average  Dose:  30  minims  (2  mils).  Anti- 
dotes: morphine,  pilocarpine,  physostigmine,  aconitine;  stim- 
ulants. 


SQUIBB'S  MATERIA  MEDICA       277 

TINCTURE  IGNATIA. 

Tinctura  Ignatite,  N.  F.  Assays  0.18  to  0.22  Gm.  alkaloids  in 
100  mils  (Cc.).  Nerve  Stimulant,  Bitter  Stomachic;  in 
chronic  constipation,  neuralgia,  nervous  depression,  etc.  Aver- 
age Dose:  10  minims  (0.6  mil  [Cc.]).  Antidotes:  tannin,  then 
emetics;  chloral  hydrate  with  bromides  per  rectum;  chloroform 
by  inhalation,  if  required. 

©  Tincture  Iodine,  Squibb     g.  s.  bottle,  pint        ;  |4  Pmt 

Tinclura  loJi.  7  Gm.  iodine  and  5  Gm.  potassium  iodide  in 
100  mils  (Cc.).  Antiseptic,  Discutient,  Counter-irritant,  Al- 
terative. Average  Dose:  l'/2  minims  (0.1  mil).  Externally 
undiluted  or  with  equal  volume  alcohol.  Antidotes:  apomor- 
phine  hypodermically;  starch  paste  or  flour  in  warm  water; 
demulcents. 

Tincture  Iodine  Stronger,  Squibb 

(Churchill's  Tincture)  g.  s.  bottle,  pint         ;  %  pint 

Tinctura  lodl  Forlior,  N.  F.  100  mils  (Cc.)  contains  16.5  Gm. 
iodine  and  3.3  Gm.  potassium  iodide.  Dose:  \/2  to  I  minim 
(0.03  to  0.06  mil). 

TINCTURE  IODINE  DECOLORIZED. 

Tinclura  lodi  Decolorata,  N.  F.  Practically  an  alcoholic  solu- 
tion of  sodium  and  ammonium  iodides  for  external  use  as 
Discutient.  Contains  8.3  Gm.  iodine  per  100  mils  (Cc.)  in 
combined  form,  no  free  iodine. 

t  Tincture  Ipecac  and  Opium,  Squibb 

pint         ;  j/4  pint 

Tinclura  Iftecacuanh<e  el  Opii,  N.  F.;  Liquid  Dover's  Powder; 
Tincture  Dover's  Powder.  Made  from  a  depurated  solution 
of  opium,  and  hence  contains  only  the  valuable  anodyne  and 
hypnotic  principles  of  opium,  beside  the  ipecac  constituent. 
100  mils  (Cc.)  represent  10  Gm.  each  deodorized  opium  and 
ipecac.  Diaphoretic,  Anodyne,  Antispasmodic.  Average 
Dose :  8  minims  (0.5  mil)  (containing  nearly  i/10  grain  mor- 
phine). Antidotes:  potassium  permanganate  solution  (2  grains 
in  water),  then  emetics;  atropine  or  strychnine  hypodermically. 

©  Tincture  Iron  Chloride,  Squibb 

g.  s.  bottle,  pint,          ;  ]/4  pint,          ;  oz. 

Tinclura  Fe.nl  ChloriJi;  Tincture  Iron  Per-  or  Sesqui-chloride. 
Contains  35  volume  percent,  solution  ferric  xhlonde  (equal  to 
13  percent,  ferric  chloride,  or  4.48  percent,  iron),  with  alcohol. 
Styptic,  Astringent;  Hematinic.  Average  Dose :  8  minims  (0.5 
mil  [Cc.]),  well  diluted.  Incompatible  with  alkalies,  alkali 
benzoates,  antipyrine,  tannin,  and  vegetable  infusions,  tinctures 
or  decoctions. 

If  difficulty  is  experienced  in  procuring  any  Squibb  product, 
in  the  original  packages  here  listed,  please  notify  us;  we 
shall  see  that  your  wants  are  met  promptly  and  satisfactorily. 


278       SQUIBB'S  MATERIA  MEDICA 

TINCTURE  IRON  CHLORIDE,  ETHEREAL. 

Tinctura  Ferri  ChloriJi  /fathered,  N.  F.;  Bestuscheff's  Tincture; 
Lamotte's  Drops.  1  fluidounce  represents  about  4  grains  iron 
and  120  minims  ether.  Hematinic.  Average  Dose:  30  minims 
(2  mils  [Cc.]).  Incompatible  with  vegetable  decoctions,  in- 
fusions or  tinctures. 

Tincture  Iron  Citro=Chloride,  Squibb 

g.  s.  bottle,  pint,          ;  '/£  pint 

Tinctura  Ferri  Citro-Chloridi,  N.  F.;  Tasteless  Tincture  Iron. 
Combining  solution  iron  chloride  with  sodium  citrate,  in  alcohol. 
Same  iron  strength  as  official  Tincture  Iron  Chloride.  Hema- 
tinic. Average  Dose:  8  minims  (0.5  mil  [Cc.]). 

Tincture  Iron,  Tasteless.     See  Tincture  Iron  Citro-Chloride. 

TINCTURE  JALAP 

Tinctura  Jalafxe,  N.  F.  20  Gm.  jalap  in  100  mils  (Cc.).  Hy- 
dragogue  Cathartic.  Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

TINCTURE  JALAP  COMPOUND. 

Tinctura  Jalaps  Composite,  N.  F.  Each  fluidounce  represents 
about  57  grains  jalap  and  14'/^  grains  resin  scammony.  Hydra- 
gogue  Cathartic.  Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

Tincture  Kino,  Squibb  pint         ;  |4  pint 

Tinctura  Kino.  Representing  10  Gm.  kino  in  100  mils  (Cc.), 
as  against  5  Gm.  U.  S.  P.  VHIth  Rev.  Intestinal  and  Pharyn- 
geal  Astringent.  Average  Dose:  1  fluidrachm  (4  mils). 

f  TINCTURE  KINO  AND  OPIUM. 

Tinclura  Kino  et  Opii  Composiia,  N.  F.;  Tincture  Kino  Com- 
pound. Each  fluidounce  represents  about  4.6  grains  each  kino 
and  opium,  with  spirit  camphor,  aromatic  spirit  ammonia  arid 
oil  cloves.  Intestinal  Astringent,  Carminative;  chiefly  in  colic 
and  acute  diarrhea.  Average  Dose:  1  fluidrachm  (4  mils 
[Cc.]). 

TINCTURE  KRAMERIA. 

Tinclura  K,ramerice,  N.  F. ;  Tincture  Rhatany.  20  Gm.  in  100 
mils  (Cc.).  Internal  and  Exlernal  tannin-bearing  Astringent. 
Average  Dose:  I  fluidrachm  (4  mils);  externally  in  10  percent, 
dilution. 

TINCTURE  LACTUCARIUM. 

Tincttira  Laclucarii.  50  Gm.  lactucarium  in  100  mils  (Cc.), 
with  25  mils  glycerin.  Cough  Sedative,  Anlispasmodic.  Aver* 
age  Dose:  30  minims  (2  mils). 

TINCTURE  LARKSPUR. 

Tinclura  Delphinii,  N.  F.  10  Gm.  drug  to  100  mils  (Cc.). 
External  Parasiticide.  Antidotes:  tannin,  emetics;  ammonia, 
digitalis,  brandy. 


SQUIBB'S  MATERIA  MEDICA        279 

Tincture  Lavender  Compound,  Squibb 

pint         ;  J4  pint 

Tinclura  Lavandula  Composite;  Lavender  Drops;  Compound 
Spirit  Lavender.  Containing  in  1000  mils  (Cc.)  8  mils  oil 
lavender  flowers,  2  mils  oil  rosemary,  20  Gm.  Saigon  cinnamon, 
5  Gm.  clove,  and  10  Gm.  each  nutmeg  and  red  saunders. 
Rubefacient;  Carminative,  Aromatic  Flavoring.  Average  Dose: 
30  minims  (2  mils). 

Tincture  Lemon  Peel,  Squibb  pint         ;  %  pint 

Tinctura  Limonis  Corticis.  50  Gm.  fresh  peel  in  100  mils 
(Cc.).  Flavoring  ingredient. 

©  Tincture  Lobelia,  Squibb  pint         ;  14  pint 

Tinclura  Lobelia.  10  Gm.  drug  in  100  mils  (Cc.).  Expector- 
ant, Emetic.  Average  Dose:  expectorant,  15  minims  (1  mil); 
emetic,  I  fluidrachm  (4  mils). 

TINCTURE  MUSK. 

Tinctura  Moschi.  5  Gm.  musk  in  100  mils  (Cc.).  Analeptic, 
Antispasmodic.  Average  Dose:  I  fluidrachm  (4  mils). 

©  Tincture  Myrrh,  Squibb  pint        ;  %  pint 

Tinctura  Myrrhce.  20  Gm.  myrrh  in  100  mils  (Cc.). 
Astringent  Protective,  externally;  Carminative,  internally.  In- 
compatible with  aqueous  liquids.  Average  Dose :  1 5  minims 
(1  mil). 

TINCTURE  NUTGALL. 

Tinctura  Calls,  N.  F.  Dropped  from  U.  S.  P.  20  Gm.  nut- 
gall  with  10  mils  (Cc.)  glycerin  in  100  mils.  Astringent. 
Average  Dose:  1  fluidrachm  (4  mils). 

©  Tincture  Nux  Vomica,  Squibb          pint         ;  %  pint 

Tinclura  Nucis  Vomlcee.  Made  direct  from  the  drug;  not 
from  extract  nux  vomica  as  in  U.  S.  P.  VHIth  Rev.  Assays 
0.237  to  0.263  Gm.  alkaloids  in  100  mils  (Cc.).  Bitter  Stom- 
achic, Nerve  Stimulant.  Average  Dose:  8  minims  (0.5  mil). 
Antidotes:  tannin,  then  emetics;  chloral  hydrate  with  bromides 
per  rectum;  chloroform  by  inhalation  if  required. 

f  Tincture  Opium,  Squibb  pint         ;]4Pmt 

Depurated  Tincture  Opium;  Squibb 's  Laudanum.  Prepared  by 
a  process  devised  by  Dr.  E.  R.  Squibb  whereby  the  odorous 
and  other  noxious  principles  of  opium  are  removed  while  the 
therapeutically  valuable  constituents  are  retained.  Therapeutic- 
ally  superior  to  strictly  U.  S.  P.  tincture  opium.  Assays  about 
1  Gm.  anhydrous  morphine  in  100  mils  (Cc.).  Antispas- 


The  Squibb  products  are  recognized  everywhere  as  the  Quality 
Standard.  They  are  of  uniform  purity  and  strength,  hence 
theraupeutically  dependable.  When  ordering  or  prescribing  medi- 
cinal products,  you  will  do  well  always  to  specify  SQUIBB'S. 


280       SQUIBB'S  MATERIA  MEDICA 

|  Tincture  Opium,  Squibb  (Cont.) 

modic,  Antiphlogistic,  Anodyne,  Cerebrospinal  Depressant. 
Average  Dose :  8  minims  (0.5  mil) .  Acts  in  20  minutes ;  com- 
pletely eliminated  in  48  hours.  Antidotes:  potassium  perman- 
ganate (2  grains  in  solution),  then  emetics;  atropine  or  strych- 
nine hypodermically ;  hot  strong  coffee;  exercise. 

TINCTURE  OPIUM  ACETATED.    See  Vinegar  Opium. 

Tincture  Opium  Camphorated,  Squibb 

pint 

Tinclura  Opii  Camphorala;  Paregoric;  Elixir  Paregoric.  Each 
fluidounce  represents  about  1 .8  grains  each  opium,  benzoic  acid 
and  camphor,  and  1 .9  minims  oil  anise,  in  diluted  alcohol  with 
a  little  glycerin.  Carminative,  Anodyne.  Average  Dose :  1 
fluidrachm  (4  mils  [Cc.]),  diluted. 

f  Tincture  Opium  Compound,  Squibb 

pint         ;  '/4  pint         ;  oz. 

Squibb 's  Diarrhea  Mixture;  Mixture  Opium  and  Chloroform 
Compound.  Each  fluidrachm  contains  about  12  minims  each 
tincture  opium,  tincture  capsicum  and  spirit  camphor,  and  4J/2 
minims  chloroform,  with  alcohol, — all  U.  S.  P.  1860  strength. 
Dose:  for  persons  over  18  years,  a  teaspoonful;  from  14  to  18 
yrs.,  a  small  teaspoonful;  from  10  to  14  yrs.,  half  teaspoonful; 
from  6  to  10  yrs.,  30  drops;  from  2  to  6  yrs.,  10  to  30  drops; 
for  infants,  1  to  10  drops,  according  to  age;  always  well 
diluted. 

f®  Tincture  Opium  Deodorized,  Squibb 

pint         ;  |/^  pint 

Tinclura  Opii  DeoJorali.  Assays  0.95  to  1.05  Gm.  anhydrous 
morphine  in  100  mils  (Cc.).  Action,  dose,  etc.:  as  of  regular 
tincture  opium. 

t  TINCTURE  OPIUM  WITH  SAFFRON. 

Tinctura  Opii  Crocala,  N.  F.;  Sydenham's  Laudanum.  Same 
strength  as  tincture  opium,  but  containing  in  each  100  mils 
(Cc.)  2.5  Gm.  saffron  and  0.6  Gm.  each  cinnamon  and  clove. 
Sedative,  Carminative.  Average  Dose:  10  minims  (0.6  mil). 

TINCTURE  ORANGE  PEEL,  BITTER. 

Tinclura  Auranlii  Amari.  20  Gm.  bitter  orange  peel  in  100 
mils  (Cc.).  Flavoring  ingredient;  Aromatic  Bitter  Stomachic. 
Average  Dose:  I  fluidrachm  (4  mils). 

Tincture  Orange  Peel,  Sweet,  Squibb 

pint         ;  ]/4  pint 

Tinctura  Auranlii  Dulcis.  50  Gm.  grated  fresh  sweet  orange 
peel  in  100  mils  (Cc.).  Flavoring  ingredient;  Stomachic. 
Average  Dose:  1  fluidrachm  (4  mils). 


SQUIBB'S  MATERIA  MEDICA       28! 

TINCTURE  PARACOTO, 

Tinctura  Paracoto,  N.  F.  100  mils  (Cc.)  represent  12.5  Gm. 
bark.  Intestinal  Astringent.  Average  Dose :  30  minims  (2  mils 
[Cc.]). 

TINCTURE  PASSION  FLOWER. 

Tinctura  Passiflorce,  N.  F.  20  Gm.  drug  in  100  mils  (Cc.) 
diluted  alcohol.  Used  as  Nerve  Sedative,  Hypnotic.  Average 
Dose:  ace.  to  N.  F.,  10  minims  (0.6  mil);  but  as  the  fluid- 
extract  is  usually  given  in  doses  of  15  to  30  minims,  that  dose 
appears  too  small. 

TINCTURE,  PECTORAL. 

Tinctura  Pectoralis,  N.  F.;  Bateman's  Pectoral  Drops.  Each 
fluidounce  contains  20  minims  tincture  opium,  30  minims*  tinc- 
ture catechu  compound,  20  minims  spirit  camphor,  with  oil 
anise,  caramel  and  diluted  alcohol.  Cough  Sedative,  Anti- 
catarrhal.  Average  Dose  (infants):  10  minims  (0.6  mil  [Cc.]). 

TINCTURE    PELLITORY.     See    Tincture    Pyrethrum. 

Tincture  Physostigma,  Squibb  pint         ;  %  pint 

Tinctura  Physostigmatis ;  Tincture  Calabar  Bean.  Assays  0.013 
to  0.017  Gm.  alkaloids  in  100  mils  (Cc.).  Antispasmodic, 
Antineuralgic,  peristaltic.  Average  Dose:  15  minims  (I  mil). 
Antidotes:  emetics;  atropine  or  strychnine  subcutaneously ; 
chloral  hydrate ;  stimulants. 

TINCTURE  PIMPINELLA. 

Tinciura  PimpineQ.ee,  N.  F.  20  Gm.  drug  to  100  mils  (Cc.). 
Obsolescent  Diuretic,  Diaphoretic,  Stomachic.  Average  Dose: 
1  fluidrachm  (4  mils). 

TINCTURE  PULSATILLA. 

Tinctura  Pulsatillee,  N.  F.  From  herb  of  Anemone  Pulsatilla, 
1:10.  Obsolescent  Alterative,  Sedative,  Antispasmodic. 
Average  Dose:  30  minims  (2  mils  [Cc.]). 

TINCTURE  PYRETHRUM. 

Tinctura  Pyrethri ;  Tincture  Pellitory.  20  Gm.  drug  in  100 
mils  (Cc.).  Local  Irritant;  little  used. 

TINCTURE  QUASSIA. 

Tinctura  Quassia.  20  Gm.  drug  in  100  mils  (Cc.).  Bitter 
Stomachic,  Vermifuge.  Average  Dose :  30  minims  (2  mils) . 

TINCTURE  QUILLAJA. 

Tinctura  Quillajce,  N.  F.;  Tincture  Soap-bark.  Dropped  from 
U.  S.  P.  20  Gm.  drug  in  100  mils  (Cc.).  Expectorant;  emul- 
sifier  and  foam-producer.  Dose:  15  to  30  minims  (1  to  2 
mils). 

Since  we  make  only  one  quality  of  each  product,  that  best 
suited  to  the  purposes  intended,  the  specification  "Squibb's" 
is  not  open  to  various  interpretations,  but  has  a  plain,  positive 
meaning.  When  ordering  or  prescribing,  specify  SQUIBB'S. 


282        SQUIBB'S  MATERIA  MEDICA 

TINCTURE  RHATANY.     See  Tincture  Krameria. 

Tincture  Rhubarb,  Squibb  pint         ;%  pint 

Tinctura  Rhei.  20  Gm.  rhubarb,  3  Gm.  cardamom  and  10 
mils  (Cc.)  glycerin,  in  100  mils.  Stomachic,  Laxative.  Aver- 
age Dose:  I  fluidrachm  (4  mils). 

TINCTURE  RHUBARB  AQUEOUS. 

Tinctura  Rhei  Aquosa,  N.  F.  10  Gm.  rhubarb  in  100  mils 
(Cc.),  with  1  Gm.  potassium  carbonate  and  cinnamon  water  as 
corrigent.  1  fluidounce  represents  45.6  grains  rhubarb.  Laxa- 
tive, Stomachic.  Average  Dose:  1  fluidrachm  (4  mils). 

©  Tincture   Rhubarb  Aromatic,   Squibb 

pint         ;  ]/4  pint 

Tinctura  Rhei  Aromalica.  20  Gm.  rhubarb,  4  Gm.  each  Saigon 
cinnamon  and  clove,  2  Gm.  nutmeg,  and  10  mils  (Cc.)  glycerin, 
in  100  mils.  Each  fluidounce  represents  about  91  grains  rhu- 
barb, 18  grains  Saigon  cinnamon,  18  grains  clove  and  9  grains 
nutmeg.  Stomachic,  Carminative,  Laxative.  Average  Dose: 
30  minims  (2  mils). 

TINCTURE  RHUBARB  AND  GENTIAN. 

Tinclura  Rhei  el  Cenliancs,  N.  F.  Each  fluidounce  represents 
about  32  grains  rhubarb  and  8  grams  gentian.  Laxative,  Bitter 
Tonic.  Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

TINCTURE  RHUBARB  SWEET. 

Tinclura  Rhei  Dulcis,  N.  F.  Each  fluidounce  represents 
453/t;  grains  rhubarb,  18'/4  grains  licorice,  18'/4  grains  anise, 
41/2  grains  cardamom,  48  minims  glycerin,  alcohol  and  water. 
Stomachic,  Laxative.  Average  Dose:  30  minims  (2  mils  [Cc.]). 

TINCTURE  RHUBARB  VINOUS.     See  Wine  Rhubarb  Compound. 

TINCTURE  SAFFRON. 

Tinctura  Croci,  N.  F.  10  Gm.  saffron  in  100  mils  (Cc.) 
diluted  alcohol.  Coloring. 

Tincture  Sanguinaria,  Squibb  pint  ;   %  pint 

Tinclura  Sanguinaria;  Tincture  Blood-root.  10  Gm.  drug  and 
1  mil  (Cc.)  hydrochloric  acid  in  100  mils.  Expectorant. 
Average  Dose:  15  minims  (1  mil). 

TINCTURE  SAW  PALMETTO  AND  SANTAL. 

Tinclura  Sabal  el  Sanlali,  N.  F.  20  Gm.  saw  palmetto  and  6.5 
Gm.  sandalwood  in  100  mils  (Cc.).  Genito-urmary  Anticatarrhal, 
like  oil  sandalwood.  Average  Dose :  1  fluidrachm  (4  mils). 

TINCTURE  SERPENTARIA. 

Tinclura  Serpenlaria,  N.  F.;  Tincture  Virginia  Snake  Root. 
Dropped  from  U.  S.  P.  20  Gm.  drug  in  100  mils  (Cc.). 
Bitter,  similar  to  gentian.  Average  Dose :  1  fluid'rachnr(4  mils). 


SQUIBB'S  MATERIA  MEDICA       283 

Tincture  Soap  Camphorated.         See  Liniment  Soap. 

TINCTURE  SOAP  GREEN  COMPOUND.  See  Liniment  Soap  Soft 
Compound. 

Tincture  Soap  Soft.          See  Liniment  Soap  Soft. 

0  TINCTURE  SQUILL. 

Tlnclura  ScillcE.  10  Gm.  drug  in  100  mils  (Cc.).  Nauseant 
Expectorant.  Average  Dose:  15  minims  (1  mil). 

Tincture,  Stomachic.        See  Tincture,  Bitter. 

Tincture  Stramonium  Leaves,  Squibb 

pint          ;  ]/4  pint 

Tinctura  Stramonii.  Assays  0.0225  to  0.0275  Gm.  alkaloids  in 
100  mils  (Cc.).  Antispasmodic,  Sedative,  Analgesic.  Average 
Dose:  8  minims  (0.5  mil). 

0  Tincture  Strophanthus,  Squibb 

pint          ;  J/4  pint          ;  oz. 

Tinctura  Strophanthi.  10  Gm.  strophanthus  in  100  mils  (Cc.). 
Fat-free.  Physiologically  assayed  by  U.  S.  P.  method  and 
standardized ;  minimum  lethal  dose  not  greater  than  0.0006  mil 
per  Gm.  weight  of  frog.  Cardiac  Stimulant,  like  digitalis;  its 
absorption  from  alimentary  canal  is  very  variable.  Average 
Dose:  8  minims  (0.5  mil).  Antidotes:  emetics;  atropine,  picro- 
toxine,  camphor;  brandy. 

TINCTURE  SUMBUL. 

Tinctura  Sumbul,  N.  F.  10  Gm.  drug  in  100  mils  (Cc.). 
Used  as  Nerve  Stimulant,  Antispasmodic;  chiefly  in  hysteria. 
Average  Dose:  1  fluidrachm  (4  mils). 

Tincture  Sweet  Orange  Peel.  See  Tincture  Orange  Peel 
Sweet. 

TINCTURE  TOLU. 

Tinctura  Tolulana.  20  Gm.  balsam  tolu  in  100  mils  (Cc.). 
Expectorant;  Flavoring,  with  other  cough  remedies.  Average 
Dose:  30  minims  (2  mils). 

Tincture  Turmeric.         See  Indicators  (Part  IV). 

Tincture  Valerian,  Squibb 

Tinclura  Valerians.  20  Gm.  valerian  in  100  mils  (Cc,). 
Used  as  Nerve  Sedative,  Antispasmodic;  in  hysteria,  etc. 
Average  Dose:  1  fluidrachm  (4  mils). 

The  founder  of  the  House  of  Squibb,  Dr.  Edward  R.  Squibb, 
not  only  had  high  ideals,  but  lived  and  labored  for  them;  and, 
in  the  words  of  William  Miller  Bartlett,  "the  House  of  Squibb 
stands  today  as  a  living  monument  to  the  honor,  integrity,  zeal 
and  devotion  of  its  founder." 


284        SQUIBB'S  MATERIA  MEDICA 

0  Tincture  Valerian  Ammoniated,  Squibb 

pint         ;  J4  pint 

Tinclura  Valerianat  Ammoniala.  20  Gm.  valerian,  with  aro- 
matic spirit  ammonia,  in  100  mils  (Cc.).  Nerve  Sedative,  Anti- 
spasmodic.  Average  Dose:  30  minims  (2  mils). 

Tincture  Vanilla,  Squibb  pint         ;  '/4  pint 

Tinclura  Vanilla,  N.  F.  Dropped  from  U.  S.  P.  A  pure 
and  genuine  product,  made  from  choicest  Mexican  vanilla 
beans,  10  Gm.  per  100  mils  (Cc.).  Free  from  adulterant  of 
any  nature,  so  commonly  used  in  the  so-called  "Extracts  of 
Vanilla."  Flavoring. 

Tincture  Vanillin  Compound,  Squibb    pint        ;  ]4  pint 

Tinclura  Vanillini  Composite,  N.  F.  III.  Dropped  from  pres- 
ent N.  F.,  but  still  in  common  use  as  a  flavoring  agent.  0.65 
Gm.  vanillin  and  0.04  Gm.  coumarin,  in  100  mils  (Cc.),  with 
alcohol,  glycerin,  syrup  and  compound  tincture  cudbear. 

Tincture  Veratrum  Viride,  Squibb       pint        ;  14  pint 
Tinclura    Veralri    Viridis.      10   Gm.   drug    in    100   mils    (Cc.)- 
Cardiac    and    Circulatory    Depressant,    Diaphoretic.      Average 
Dose:  8  minims   (0.5  mil    [Cc.]).   Antidotes:  tannin,  emetics; 
morphine  with  atropine,  hypodermically;  stimulants. 

Tincture  Viburnum  Compound,  Squibb 

pint          ;  ]4  pint 

Tinclura  Viburni  Opuli  Composita,  N.  F.  Each  fluidounce 
represents  about  16J/^  grains  viburnum  opulus,  16J/j  grains 
dioscorea,  4^5  grains  scullcap,  23  grains  clove,  30  grains  cin- 
namon. Used  as  Uterine  Tonic  and  Antispasmodic,  in  mens- 
trual disorders.  Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

Tincture,   Warburg's.     See  Tincture  Antiperiodic. 

TINCTURE  ZEDOARY  BITTER. 

Tinctura  Zedoariae  Amara,  N.  F.;  Compound  Tincture 
Zedoary.  Each  fluidounce  represents  11^/5  grains  zedoary, 
57/io  grains  aloes,  2^4  grains  each  rhubarb,  gentian,  agaric  and 
saffron,  with  glycerin,  alcohol  and  water.  Bitter  Stomachic, 
Laxative.  Average  Dose:  1  fluidrachm  (4  mils  [Cc.]). 

Tolu,  Soluble.       See  Fluid  Tolu. 

®  Tragacanth,  Squibb 

*Ribbons  tin,  Ib.         ;  14  lb. 

Powdered  tin,  lb.         ;  ]4  lb. 

Tragacantha.  Gummy  exudation  from  stems  of  Astragalus 
gummifer  or  other  species  of  Astragalus  (Fam.  Leguminosae) . 
First  quality,  free  from  foreign  gums  and  starchy  adulterants. 
Demulcent;  Emulsifier,  Adhesive. 


SQUIBB'S  MATERIA  MEDICA       285 

TRIBROMOMETHANE,     See   Bromoform. 

TRIFERRIN. 

Iron  Paranucleinate.  Reddish,  tasteless  powder;  22  percent. 
iron,  2.5  percent,  phosphorus  in  organic  combination.  Insoluble 
in  ordinary  solvents.  Hematinic.  Dose:  5  grains  (0.3  Gm.). 

TRIFOLIUM. 

Trifolium,  N.  F.;  Red  Clover.  Dried  flowers  of  Trifolium 
pratense  (Fam.  Leguminosa)  .  Used  in  Antiluetic  and  Altera- 
tive compounds,  also  as  Expectorant;  considered  inert  by  many. 
Average  Dose:  60  grains  (4  Gm.).  Given  chiefly  as  fluid  - 
extract,  which  see. 

Trihydroxybenzene.     See  Pyrogallol  (Acid  Pyrogallic). 
Triiodomethane.       See  lodoform. 
TRIKRESOL.    Brand  of  Cresol. 

TRILLIUM. 

Trillium,  N.  F.;  Beth  Root.  Dried  rhizome  of  Trillium 
erectum  (Fam.  Liliaceai).  Obsolescent  Astringent.  Tonic, 
Average  Dose:  2  Gm.  (30  grains).  (See  also  Fluid  extract.) 

Trimethylxanthine.        See  Caffeine. 

TRINITROPHENOL. 

Trinitrophenol  ;     Acid     Picric.       CeHsNaC^.       Newly     offi- 


cial. Yellow,  odorless,  very  bitter  crystals.  1  Gm.  dissolves 
in  78  mils  (Cc.)  water,  12  alcohol,  35  chloroform,  65  ether. 
Explodes  when  heated  rapidly  or  subjected  to  percussion.  An- 
tiseptic and  Keratoplastic,  in  burns  (0.5  to  1  %  solu- 
tion), erysipelas  (2  to  6%  hydroalcoholic  solution),  wounds 
C/4  to  1%  solution),  etc.;  Antiperiodic,  internally.  Also  Re- 
agent. Average  Dose:  1  grain  (0.065  Gm.).  Antidotes:  white 
of  egg,  then  emetics;  sodium  sulphate;  transfusion  with  alkaline 
sodium  chloride  solution.  NOTE:  Should  be  applied  cautiously, 
owing  to  the  danger  from  absorption. 

TRIONAL.     Brand  of  Sulphonethylmethane. 
TRIOXYMETHYLENE.     See    Paraformaldehyde. 

TRITICUM. 

Triticum  ;  Couch  Grass;  Dog  Grass.  Dried  rhizome  of 
Agropyron  repens  (Fam.  Gramineat).  Odor  slight;  taste  sweet. 
Used  as  Diuretic,  in  cystitis  and  irritable  bladder.  Average 
Dose:  120  grains  (8  Gm.).  (See  also  Fluidextract.)  . 


The  Squibb  Ideals  have  taken  concrete  form  in  the  Squibb 
Products;  these  are  universally  recognized  as  standards  of 
uniform  Purity  and  Efficacy,  that  is,  general  Excellence  and 
Reliability.  Specify  SQUIBB'S  when  prescribing  or  ordering. 


286       SQUIBB'S  MATERIA  MEDICA 

TRITURATION  ELATERIN. 

Triiuralio  Elalerini.  10  percent,  elaterin.  Powerful  Hydra- 
gogue  Cathartic.  Average  Dose:  Yi  grain  (0.03  Gm.). 

Troches,    Squibb.         See   end   of   Tablet   list    (Part   II). 

f  TROPACOCAINE  HYDROCHLORIDE. 

Benzoylpseudotropeine  Hydrochloride.  CgHi^NO.C-HsO.- 
HC1.  Colorless,  acicular  crystals.  Soluble  freely  in  water. 
Local  Anesthetic,  like  cocaine. 

TRYPSIN. 

Proteolytic  enzyme  of  the  pancreas.  Light-yellow  powder; 
faint  odor;  meaty  taste.  Slowly  and  incompletely  soluble  in 
water.  Digestive,  solvent  of  false  membranes;  also  been  used 
on  malignant  tumors.  Dose:  1  to  2  grains  (0.065  to  0.13  Gm.) 
with  sodium  bicarbonate. 

Turlington's   Balsam.        Tincture  Benzoin  Compound. 

©  TURPENTINE. 

Terebinthina,  N.  F.  Concrete  oleoresin  from  Pinus  palustris  and 
other  species  of  Pinus  (Fam.  Pinacece).  Yellowish,  opaque, 
sticky  masses;  characteristic  odor  and  taste.  Freely  soluble  in 
alcohol,  ether,  chloroform.  Source  of  oil  turpentine. 

TURPENTINE,  VENICE. 

Terebinthina  Laricis,  N.  F.;  Larch  Turpentine.  Viscid 
oleoresin  from  Larix  enropcea  (Fam.  Plnaces).  Yellowish 
or  greenish,  thick  liquid;  distinctive  odor;  bitter,  characteristic 
taste.  Soluble  in  alcohol,  chloroform;  insoluble  in  water. 
Rubefacient  externally;  Anticatarrhal  internally.  Dose:  3  to  5 
grains  (0.13  to  0.3  Gm.). 

Turpeth   Mineral.         See  Mercury  Subsulphate  Yellow. 
UNGUENTUM  CREDE.     See  under  Collargol. 
UNICORN  ROOT.     See  Aletris. 
UNICORN  ROOT,  FALSE.    See  Helonias. 
UNNA'S  DERMATOLOGICAL  PASTES.    See  Pastes. 

URANIUM  NITRATE. 

L'ranii  Niiras.  UO^NO^.bHiiO.  Light-yellow,  odorless, 
bitter,  astringent,  slightly  efflorescent  crystals.  1  Gm.  dissolves 
in  1.2  mils  (Cc.)  water;  freely  soluble  in  ether  or  alcohol. 
Used  in  diabetes  and  cancer.  Average  Dose:  J/£  grain  (0.01 
Gm.).  (See  also  Reagents  [Part  IV].) 


SQUIBB'S  MATERIA  MEDICA       287 

Urea  Apparatus,  Squibb 

For  the  estimation  of  urea  in  urine.  Complete  in  box,  with 
materials  for  making  Solution  Chlorinated  Soda  and  full  direc- 
tions for  use. 

For  those  who  prefer  to  employ  Solution  Sodium  Hypobromite 
(rather  than  Solution  Chlorinated  Soda)  as  a  reagent  with  this 
apparatus,  we  offer  the  materials  for  its  manufacture,  viz: 

lOOCc.    500  Cc. 

Solution  Sodium  Hydroxide   (28.5%) 

Solution  Bromine  (12.5%) 

(These  solutions  mixed  in  equal  proportions  produce  Solution 
Sodium  Hypobromite.) 

Urease,   Squibb 

10  Gm.  vial,  ;  0.1  Gm.  Tablets,  bottle  of  100, 
Soluble  urea-splitting  enzyme  of  the  Jack  Bean,  compounded 
with  potassium  phosphates  in  proportion  to  produce  the  quick- 
est and  most  complete  activity  according  to  the  researches  of 
Dr.  D.  D.  Van  Slyke.  An  improved  agent  for  the  rapid 
estimation  of  urea  in  urine,  blood,  spinal  fluid,  etc.  Its  urea- 
splitting  power  is  greater  than  that  of  urease  from  the  soya 
bean,  and  it  contains  less  foreign  protein  in  proportion  to  its 
enzymatic  activity  when  tested  by  the  absolute  method  of  Van 
Slyke.  Write  for  complete  literature. 

URITONE  and  UROTROPIN.     Brands  of  Hexamethylenamine. 

UVA  URSI. 

Uva  Ursi;  Bearberry  Leaves.  Dried  leaves  of  Arciosiaphylos 
Uva-ursi  (Fam.  Ericaceae).  Diuretic,  Urinary  Anticatarrhal. 
Average  Dose:  30  grains  (2  Gm.).  (See  also  Fluidextract.) 

0  VALERIAN. 

Valeriana.  Dried  rhizome  and  roots  of  Valeriana  officinalis 
(Fam.  Valerianacea).  Odor  unpleasant;  taste  camphoraceous, 
somewhat  bitter.  Used  as  Nerve  Sedative,  Antispasmodic ;  in 
hysteria  and  other  nervous  excitations.  Average  Dose  :  30  grains 
(2  Gm.).  (See  also  Tincture.) 

VALERYLDIETHYLAMIDE.     See  Valyl. 

VALIDOL. 

Menthol  Valerate  with  30  percent,  free  menthol.  Colorless, 
thick  liquid;  mild,  pleasant  odor;  cooling,  slightly  bitter  taste. 
Soluble  readily  in  alcohol,  ether,  chloroform,  or  oils;  insoluble 
in  water.  Nerve  Sedative,  Analgesic,  Carminative.  Dose:  10 
to  20  drops. 


The  Squibb  Label  on  a  package  is  a  positive  guaranty  for  the 
uniform  Purity  and  Reliability  of  the  product.  We  make  only 
ONE  quality:  the  SQUIBB  quality;  and  our  prices  are  as  low 
as  they  can  be  made  for  that  quality.  Specify  SQUIBB'S. 


28S        SQUIBB'S  MATERIA  MEDICA 

Vallet's   Mass.        See  Mass  Ferrous  Carbonate. 

VALYL. 

Valeryldiethylamide.  Colorless  liquid;  pungent  odor;  burning, 
valerian-like  taste.  Soluble  in  about  25  parts  water,  easily  in 
alcohol  or  ether.  Nerve  Sedative,  Antineuralgic.  Dose :  2  to 
6  minims  (0.13  to  0.4  mil  [Cc.]). 

VANILLA. 

Vanilla,  N.  F.;  Vanilla  Bean.  Cured,  full-grown,  unripe 
fruit  of  Vanilla  planifolia  (Fam.  Orc/ii'Jacece) .  Flavoring. 

Vanillin,  Squibb  bottle,  oz. 

Vanillinum.  CgHgOs.  Methylprotocatechuic  Aldehyde,  ob- 
tained from  vanilla,  or  synthetically.  Occasionally  used  as 
Stimulant  and  Aphrodisiac,  but  chiefly  as  Flavoring.  Aver- 
age Dose:  1/2  grain  (0.03  Gm.). 

VENICE    TURPENTINE.     See    Turpentine,    Venice. 

VERATRINE. 

Veralrina.  Natural  mixture  of  alkaloids  from  seed  of  sabadilla 
(Asagrcea  officinalis;  Fam.  Liliaceae).  White  or  grayish- 
white,  amorphous,  odorless,  sternutatory  powder;  taste  acrid, 
leaving  tingling  and  numbness  on  tongue.  1  Gm.  dissolves  in 
1760  mils  (Cc.)  water,  2.8  alcohol,  0.7  chloroform,  4.2  ether. 
Topical  Anodyne;  as  oleate  (2  percent.)  or  ointment  (4  per- 
cent.). Antidotes:  tannic  acid,  emetics;  morphine  with  atropine 
hypodermically;  demulcents;  stimulants  by  mouth. 

VERBENA. 

Verbena,  N.  F.;  Blue  Vervain.  Dried,  overground  portion  of 
Verbena  hastaia  (Fam.  Verbenacece).  Heavy  odor;  disagree- 
able, bitter  taste.  Expectorant,  Diaphoretic,  Tonic.  Average 
Dose:  15  grains  (1  Gm.). 

Veratrum  Viride,  Squibb 

Ground  for  Percolation  tin,  Ib. 

Veratrum  Viride;  Green  Hellebore;  American  Hellebore. 
Dried  rhizome  and  roots  of  Veralrum  viride  (Fam.  L/'/iaceffi). 
When  powdered,  it  is  strongly  sternutatory;  taste,  bitterish  acrid. 
Cardiac  Depressant,  Diaphoretic.  Average  Dose :  I  grain 
(0.065  Gm.).  See  also  Fluidextract;  Tincture.) 

Vermilion.         See  Mercury  Sulphide,  Red. 
VERONAL.     See  Barbital. 
VERONAL-SODIUM.     See   Barbital-Sodium. 
VERVAIN.     See   Verbena. 


SQUIBB'S  MATERIA  MEDICA         289 

VIBURNUM  OPULUS. 

Viburnum  Opulus,  N.  F.;  Cramp  Bark.  Dried  bark  of  Vibur- 
num  Opulus  var.  americanum  (Fam.  Caprifoliacete).  Strong 
odor;  astringent  bitter  taste.  Used  as  Uterine  Antispasmodic 
and  Tonic.  Average  Dose:  30  grains  (2  Gm.).  (See  also 
Fluidextract;  Tincture.) 

VIBURNUM   PRUNIFOLIUM. 

Viburnum  Prunifolium;  Black  Haw.  Dried  bark  of  Vibur- 
num prunifolium  or  of  V.  Lentago  (Fam.  Capri foliacece) . 
Slight,  peculiar  odor;  bitter,  very  astringent  taste.  In  vogue 
as  Uterine  Sedative  and  Tonic,  in  dysmenorrhea  and  habitual 
abortion.  Average  Dose:  30  grains  (2  Gm.).  (See  also 
Fluidextract.) 

VIENNA  CAUSTIC  OR  LIME.    See  Potassa  with  Lime. 

VINEGAR,   AROMATIC. 

Acetum  Aromalicum,  N.  F.  Containing  oils  of  lavender,  rose- 
mary, juniper,  peppermint,  cinnamon,  lemon  and  clove,  in 
alcohol,  acetic  acid  and  water.  Cooling,  stimulating  application 
in  fever;  Condiment. 

f  VINEGAR    OPIUM. 

Ace(um  Opii,  N.  F.;  Black  Drop;  Acetated  Tincture  Opium. 
About  10  percent,  granulated  opium,  in  acetic  acid  menstruum, 
with  sugar  and  nutmeg.  Anodyne,  Antispasmodic.  Average 
Dose:  8  minims  (0.5  mil  [Cc.]).  Antidotes:  potassium  per- 
manganate (2  grains  in  water),  emetics;  atropine  or  strychnine 
hypodermically ;  hot,  strong  coffee;  exercise. 

Vinegar  Squill,  Squibb  bottle,  pint 

Acelum  Scillce.  10  percent,  squill,  with  dilute  acetic  acid. 
Yellow  to  reddish-brown  liquid.  Physiologically  assayed 
according  to  U.  S.  P.  and  standardized;  minimum  lethal  dose 
not  greater  than  0.006  mil  (Cc.)  per  Gm.  weight  of  frog. 
Expectorant,  Diuretic.  Average  Dose:  15  minims  (1  mil 
[Cc.]). 

Vinegar  Tarragon,  Squibb  bottle,        pint, 

Prepared  by  macerating  tarragon  herb  (Artemisia  Dracunculus) 
in  cider  vinegar  for  three  months.  Used  in  place  of  cider 
vinegar  in  salad  dressings,  etc. 

VlOFORM. 

lodochloroxyquinoline;  Nioform.  Greenish-yellow,  nearly 
odorless,  voluminous  powder.  Insoluble  in  ordinary  solvents. 
Antiseptic  Vulnerary. 


This  house  supplies  only  one  quality  of  each  product:  that  best 
suited  to  the  purposes  intended.  The  specification  "Squibb's" 
is  not  open  to  various  interpretations;  it  has  a  plain,  posi- 
tive meaning.  Therefore,  when  prescribing,  specify  SQUIBB'S. 


290       SQUIBB'S  MATERIA  MEDICA 

Vitriol,    Blue.         See  Copper  Sulphate. 
Vitriol,  Green.        See  Iron  Sulphate. 

Vitriol,  White.        See  Zinc  Sulphate. 

VLEMINCKX'    LOTION    OR    SOLUTION.     See    Solution    Sulphurated 
Lime. 

Volumetric  Solutions.      See  under  Reagents  (Part  IV). 
WAHOO.     See  Euonymus. 

Warburg's  Tincture.        See  Tincture  Antiperiodic. 
WASH.     See  Lotion. 

WATER  ALMOND  BITTER. 

Aqua  Amygdala  Amarce.  0.1  volume  percent,  oil  bitter  al- 
mond. Cough  Sedative;  Vehicle.  Average  Dose:  1  fluidrachm 
(4  mils  [Cc.]). 

Water  Ammonia.       See  Ammonia  Water. 

WATER  ANISE. 

Aqua  Anisi.  0.2  volume  percent,  oil  anise.  Aromatic  Car- 
minative; Vehicle.  Average  Dose:  4  fluidrachms  (15  mils 
[Cc.]). 

0  WATER  CAMPHOR. 

Aqua  Camphors.  0.8  percent,  camphor.  Nerve  Stimulant, 
Antispasmodic ;  Vehicle  for  collyria.  Average  Dose:  2J/2 
fluidrachms  (10  mils  [Cc.]). 

0  WATER  CHLOROFORM. 

Aqua  Chloroform!.  About  1/o  percent,  chloroform.  Carmina- 
tive, Gastric  Anodyne;  Vehicle.  Average  Dose:  4  fluidrachms. 
(15  mils  [Cc.]). 

0  WATER  CINNAMON. 

Aqua  Cinnamomi.  0.2  volume  percent,  cinnamon.  Carminative; 
Aromatic  Vehicle.  Average  Dose:  4  fluidrachms  (15  mils 
[Cc.]). 

WATER  CREOSOTE. 

Aqua  Creosotl.  1  vol.  percent,  creosote.  Antiseptic,  Anti- 
tubercular,  Antizymotic:  Dermic.  Average  Dose:  2J/2  fluid 
drachms  (10  mils  [Cc.]). 

0  WATER  DISTILLED. 

Aqua  Deslillala.  Water,  H^O,  purified  by  distillation.  Neu- 
tral; free  from  sulphate,  chloride,  calcium,  metals,  organic  sub- 
stances, and  carbon  dioxide. 


SQUIBB'S  MATERIA  MEDICA       291 

WATER  FENNEL. 

Aqua  Feeniculi.  0.2  vol.  percent,  oil  fennel.  Carminative; 
Vehicle.  Average  Dose:  4  fluidrachms  (15  mils  [Cc.]). 

WATER  HAMAMELIS. 

Aqua  Hamamelidis;  Witch-Hazel  Water;  Distilled  Extract 
Witch-Hazel.  Saturated  aqueous  liquid  obtained  by  distilling 
with  steam  or  water,  the  bark,  twigs  or  whole  shrub  of 
Hamamelis  virginiana  (Fam.  Hamamelidaceai),  and  adding 
15  mils  alcohol  to  each  85  mils  distillate.  Clear;  colorless; 
characteristic  odor  and  taste;  sp.  gr.  0.979  to  0.982.  Cooling 
Astringent  lotion. 

Water  Hydrogen  Dioxide.    See  Solution  Hydrogen  Dioxide. 
WATER  JAVELLE.     See   Solution   Potassa  Chlorinated. 
WATER  LEAD.    See  Solution  Lead  Subacetate  Diluted. 
WATER  LIME.     See  Solution  Calcium  Hydroxide. 

WATER  ORANGE  FLOWER. 

Aqua  Auranlii  Florum.  Equal  volumes  distilled  water  and 
stronger  orange-flower  water.  Flavoring.  . 

WATER  ORANGE  FLOWER,  STRONGER. 

Aqua  Auranlii  Florum  Forlior.  Water  saturated  with  volatile 
oil  fresh  orange  flowers,  obtained  by  distilling  fresh  orange 
fiowers  with  water. 

©WATER  PEPPERMINT. 

Aqua  Menlhce  Piperilts.  0.2  volume  percent,  oil  peppermint. 
Aromatic  Carminative;  Vehicle.  Average  Dose:  4  fluidrachms 
(15  mils  [Cc.]). 

©  WATER  ROSE. 

Aqua  Ross.  Equal  volumes  stronger  rose  water  and  distilled 
water.  Flavoring,  Perfume. 

WATER  ROSE,  STRONGER. 

Aqua  Rosce  Forlior.  Water  saturated  with  volatile  oil  rose 
petals  and  distilled. 

WATER  SPEARMINT. 

Aqua  Menthcs  Viridis.  0.2  volume  percent,  oil  spearmint. 
Carminative.  Average  Dose:  4  fluidrachms  (15  mils  [Cc.]). 

©  WAX,  WHITE. 

Cera  Alba.     Yellow  wax  bleached. 


The  prices  of  the  Squibb  Products  are  in  all  instances  as  low  as 
the  quality  and  quantity  of  ingredients  and  the  expense  of  man- 
ufacture allow.  They  include  containers,  packing  and  boxing.  Whan 
ordering  or  prescribing  medicinal  products,  specify  SQUIBB'S. 


292        SQUIBB'S  MATERIA  MEDICA 

©WAX,  YELLOW. 

Cera  Flava;  Beeswax.  Obtained  by  melting  and  purifying 
honey-comb  of  the  bee  (Aph  mellifera).  Soluble  in  chloro- 
form, ether,  oils;  sparingly  soluble  in  cold  alcohol;  insoluble 
in  water. 

WHITE  PINE  BARK. 

Pinus  Alba,  N.  F.  Inner  bark  of  Plnus  Slrobus  (Fam.  Pina- 
cece).  Expectorant.  Average  Dose:  30  grains  (2  Gm.). 

White  Pine  Compound,  Squibb 

Ground  for  Percolation  tin,  Ib. 

Mixture  of  ground  White  Pine  Bark,  Wild  Cherry  Bark, 
Spikenard  Root,  Balm  of  Gilead  Buds,  Sanguinaria  Root  and 
Sassafras  Bark,  in  the  proportions  called  for  in  N.  F.  formula 
for  Syrup  White  Pine  Compound. 

White   Precipitate.        See    Mercury    Ammoniated. 

©  Wild  Cherry,  Squibb 

Ground  for  Percolation  tin,  Ib. 

Prunus  Virginiana.  Stem-bark  of  Prunus  serotina  (Prunus  vir- 
giniana;  Fam.  Rosacece),  collected  in  autumn,  and  carefully 
dried.  Odo/  bitter-almond-like  when  macerated;  taste  astringent, 
aromatic  and  agreeably  bitter.  Sedative,  Expectorant.  Aver- 
age Dose:  30  grains  (2  Gm.).  (See  also  Fluidextract;  Syrup.) 

WILD  INDIGO.     See  Baptisia. 

©  Wine  Antimony,  Squibb  pint         ;   %  pint 

V'mum  Anlimonii,  N.  F.  About  !/4  grain  tartar  emetic  per  fluid 
drachm,  with  sherry  wine.  Nauseant  Expectorant.  Average 
Dose:  15  minims  (1  mil  [Cc.]).  Incompatible  with  alkalies 
and  their  carbonates,  antipyrine,  tannin,  and  vegetable  infusions, 
decoctions  or  tinctures  (cinchona,  rhubarb,  etc.). 

WINE  BEEF. 

V'mum  Carnis,  N.  F.;  Beef  and  Wine.  3  Gm.  extract  beef 
in  100  mils  (Cc.),  with  syrup,  alcohol,  sherry  wine,  com- 
pound spirit  orange  and  water.  Nutrient.  Average  Dose: 
2  fluidrachms  (8  mils). 

WINE  BEEF  AND  IRON. 

V'mum  Carnis  et  Fern,  N.  F.;  Beef,  Wifte  and  Iron.  Pre- 
ceding product  with  addition  of  4.6  grains  iron  and  ammonium 
citrate  per  fluidounce.  Nutrient,  Hematinic.  Average  Dose: 
2  fluidrachms  (8  mils  [Cc.]). 

WINE  CHALYBEATE.     See  Wine  Iron. 

WINE  COLCHICUM  ROOT. 

V'mum  Colchici  Cormi,  N.  F.    40  Gm.  colchicum  corm  per  100 
mils  (Cc.).     Assays  0.126  to  0.154  Gm.  colchicine  in  100  mils. 
Antipodagric,   Antineuralgic.      Average   Dose:    10  minims    (0.6 
*  mil). 


SQUIBB'S  MATERIA  MEDICA       293 

Wine  Colchicum  Seed,  Squibb  pint        ;  '/4  pin* 

Vinum  Colchici  Seminis,  N.  F.  10  vol.  percent,  fluidextract 
colchicum  seed,  with  sherry  wine  and  a  little  added  alcohol. 
Assays  0.036  to  0.044  Gm.  colchicine  in  100  mils  (Cc.).  Anti- 
podagric,  Antineuralgic.  Average  Dose:  30  minims  (2  mils 
[Cc.]). 

WINE  IPECAC.. 

Vinum  Ipecacuanha,  N.  F.  10  vol.  percent,  fluidextract  ipecac, 
with  sherry  wine  and  alcohol.  Assays  0.18  to  0.22  Gm.  alka- 
loids in  100  mils  (Cc.).  Each  fluidounce  represents  46  grains 
drug.  Expectorant,  Stomachic.  Average  Dose:  15  minims  (1 
mil  [Cc.]). 

WINE  IRON. 

Vinum  Fern,  N.  F.;  Chalybeate  Wine.  4  percent,  iron  and  am- 
monium citrate,  with  tincture  sweet-orange  peel,  syrup  and  sherry 
wine.  Mild  Hematinic.  Average  Dose:  2  fluidrachms  (8  mils 
[Cc.]). 

WINE  IRON,  BITTER. 

Vinum  Fern  Amarum,  N.  F.  Each  fluidounce  contains  about 
23  grains  soluble  iron  and  quinine  citrate,  with  tincture  sweet- 
orange  peel,  syrup  and  sherry  wine.  Bitter  Tonic,  Hemato- 
poietic.  Average  Dose:  2  fluidrachms  (8  mils  [Cc.]). 

WINE  ORANGE  COMPOUND. 

Vinum  Auranlii  Composilum,  N.  F.;  Compound  Elixir  Orange. 
From  bitter  orange  peel,  absinthium,  menyanthes,  cascarilla, 
cinnamon,  gentian  and  potassium  carbonate,  with  sherry  wine. 
Bitter;  Aromatic  Vehicle.  Average  Dose:  1  fluidrachm  (4  mils 
[Cc.]). 

WINE  PEPSIN. 

Vinum  Pepsin!,  N.  F.  Each  fluidounce  contains  about  7.8 
grains  pepsin,  with  glycerin,  hydrochloric  acid,  alcohol  and 
sherry  wine.  Gastric  Digestive.  Average  Dose:  2  fluidrachms 
(8  mils  [Cc.]).  Discolors  on  keeping. 

WINE  RHUBARB  COMPOUND. 

Vimim  Rhei  Compositum,  N.  F.;  Tincture  Rhubarb  Vinous, 
N.  F.  III.  Each  fluidounce  contains  38.4  minims  fluidextract 
rhubarb,  9.6  minims  fluidextract  bitter  orange  peel,  and  38.4 
minims  tincture  cardamom.  Laxative,  Stomachic.  Average 
Dose:  1  fluidrachm  (4  mils  [Cc.]). 

WINE,  SHERRY. 

Vinum  Xericum,  N.  F.  Obtained  by  fermenting  juice  of  fresh 
ripe  grapes  fried  from  seeds  and  skins,  and  fortifying  with 
pure  grape  brandy.  Alcoholic  content  16  to  24  percent.  Sp. 
gr.  0.985  to  1.000. 

If  difficulty  is  experienced  in  procuring  any  Squibb  product, 
in  the  original  packages  here  listed,  please  notify  us;  we 
shall  see  that  your  wants  are  met  promptly  and  satisfactorily. 


294        SQUIBB'S  MATERIA  MEDICA 

Wine  Tar,  Squibb  pint 

Vinum  Picis,  N.  F.  Contains  about  10  percent,  tar,  or  46 
grains  per  fluidounce,  with  alcohol  and  sherry  wine.  Stimu- 
lating Expectorant.  Average  Dose :  2  fluidrachms  (8  mils 
[Cc.]). 

WINE  WHITE  ASH. 

Vinum  Fraxlni,  N.  F.  50  Gm.  white  ash  bark  per  100  mils 
(Cc.)  mixture  of  sherry  wine  (7)  and  alcohol  (1).  Used  as 
Tonic,  Purgative.  Average  Dose:  1  fluidrachm  (4  mils). 

WINE  WILD  CHERRY. 

Vinum  Pruni  Virginians,  N.  F.  1  fluidounce  represents  about 
1 14  grains  wild  cherry,  with  sherry  wine  and  a  little  alcohol. 
Bitter  Tonic,  Pectoral  Sedative;  in  weak  stomach,  anorexia, 
bronchial  catarrh,  etc.  Average  Dose:  1  fluidrachm  (4  mils 
[Cc.]). 

WINE  WILD  CHERRY,  FERRATED. 

Vinum  Pruni  Virginians  Ferratum,  N.  F.  Contains  8  volum« 
percent,  tincture  iron  citro-chloride,  in  wine  wild  cherry. 
Bitter  and  Chalybeate  Tonic.  Average  Dose:  1  fluidrachm  (4 
mils  [Cc.]). 

WITCH-HAZEL  LEAVES. 

WooUFat   (Anhydrous),  Squibb  tin,  lb. 

AJeps    Lance;    Anhydrous    Lanolin.      Purified    fat    of    sheep's 
wool,  freed  from  water.     Of  faint,  peculiar  odor;    light-yeHow 
color.      Soluble    readily    in    ether    or    chloroform,    sparingly    in ' 
alcohol ;   insoluble  in  water,  but  takes  up  several  times  its  weight 
of  water.     Ointment   Base. 

©WooI=Fat   Hydrated,  Squibb  tin,  lb. 

Adeps  Lana  HyJrosus;  Lanolin.  Anhydrous  wool-fat  mixed 
with  25  to  30  percent,  of  water.  Ointment  Base,  Emollient. 

WORMWOOD.     See  Absinthium. 

XANTHOXYLUM. 

Xanthoxylum.  Dried  bark  of  Xanthoxylum  americanum  or  of 
X.  Clava-Herculis  (Fam.  Rulacea).  Inodorous;  taste  very 
pungent  and  bitterish.  Bitter  like  gentian.  Average  Dose:  30 
grains  (2  Gm.). 

YEAST  COMPRESSED. 

Cerev/siff  Fermenlatum  Compressum,  N.  F.;  Beer  Yeast. 
Moist,  living  cells  of  Saccharomyces  cerevisice  or  other  species 
of  Saccharomyces  (Fam.  Saccharomycetacece),  combined  with 
a  starchy  or  absorbent  base.  Used  in  making  fermented  milk; 
also  as  Antipyic  in  boils,  etc. 

Yellow    Bark.       Se«   Cinchona. 


SQUIBB'S  MATERIA  MEDICA        295 

YELLOW  DOCK.     See  Rumex. 
YELLOW  JASMINE.     See  Gelsemium. 
YELLOW  WASH.    See  Lotion,.  Yellow. 
Yerba  Santa.      See   Eriodictyon. 

ZEA. 

Zea,  N.  F.  Fresh  styles  and  stigmas  of  Zea  Mays  (Fam. 
Craminece).  Used  in  inflammatory  bladder  troubles.  Average 
Dose:  60  grains  (4  Gm.).  (See  also  Fluidextract.) 

ZEDOARY. 

Zedoaria,  N.  F.  Dried  rhizome  of  Curcuma  Zedoaria  (Fam. 
Zi'ngi'fceraceff).  Stomachic,  Carminative;  like  ginger.  Aver- 
age Dose:15  grains  (1  Gm.). 

Zinc,   Reagent.         See  Reagents   (Part  IV). 

©  Zinc  Acetate,  Squibb  tin        ;  |4  lb. 

Zinci  Acetas.  ZntCoHsOo^HsO.  White,  lustrous  plates; 
faint  acetous  odor;  astringent,  metallic  taste.  On  exposure  it 
effloresces  and  loses  acid.  1  Gm.  dissolves  in  2.3  mils  (Cc.) 
water,  30  alcohol.  Astringent,  Antiseptic.  Very  rarely  used 
internally.  Employed  externally  (in  gonorrhea,  conjunctivitis, 
etc.)  in  2  to  5:1000  solution.  Average  Dose:  2  grains 
(0.13  Gm.).  Incompatible  with  alkali  carbonates,  sodium 
borate,  soluble  sulphates,  vegetable  astringent  infusions,  decoc- 
tions or  tinctures.  Antidotes,  of  zinc  salts  in  general;  alkali 
carbonates,  or  tannic  acid,  emetics;  stimulants. 

Zinc  Bromide,  Squibb  g.  s.  bottle,  oz. 

Zinci  Bromidum,  U.  S.  P.  Vlllth,  Rev.  ZnBr2.  White,  odor- 
less, very  deliquescent  powder,  of  sharp,  saline,  metallic  taste. 
Soluble  readily  in  water,  alcohol,  ether  or  ammonia.  Nerve 
Sedative,  Antispasmodic ;  chiefly  in  epilepsy  and  chorea. 
Average  Dose:  2  grains  (0.13  Gm.).  Incompatible  with  acids, 
solutions  of  alkaloidal  salts,  salts  of  heavy  metals.  Keep  well 
stoppered,  in  dry  place. 

Zinc  Carbonate  Precipitated,  Squibb  carton,  lb. 

Zinci  Carbonas  Prcecipilatus.  Yields  upon  ignition  not  less  than 
68  percent,  zinc  oxide.  Impalpable,  odorless,  white,  tasteless 
powder.  Insoluble  in  ordinary  solvents.  Cutaneous  Astrin- 
gent Protective;  in  intertrigo,  abrasions,  etc.;  for  face  powders, 
etc. 


The  Squibb  products  are  recognized  everywhere  as  the  Quality 
Standard.  They  are  of  uniform  purity  and  strength,  hence 
therapeutically  dependable.  When  ordering  or  prescribing  med- 
icinal products,  you  will  do  well  always  to  specify  SQUIBB'S. 


296        SQUIBB'S  MATERIA  MEDICA 

0  Zinc  Chloride,  Squibb 

*  Granular  g.  s.  bot.        ]4  Ib.         ;  oz. 

Fused  g.  s.  bot.        ^4  Ib.         ;  oz. 

Zinci  Chloridum.  ZnClo.  White,  odorless,  very  deliquescent, 
granular  powder;  or  fused  masses;  astringent,  metallic  taste  in 
solution;  very  caustic  when  tasted  pure.  1  Gm.  dissolves  in  0.23 
mil  (Cc.)  water,  1.3  alcohol;  freely  soluble  in  glycerin. 
Escharotic,  Antiseptic,  Astringent.  Applied  as  caustic  in  sub- 
stance, 50  percent,  solution  or  20  to  40  percent,  paste;  as 
astringent,  in  0.1  to  0.5  percent,  solution.  Incompatible  with 
sodium  borate,  alkali  carbonates,  etc.  Antidotes :  demulcents, 
then  dilute  solution  of  potassium  or  of  sodium  carbonate;  emet- 
ics hypodermically;  stimulants.  Keep  securely  stoppered, 
in  dry  place. 

Zinc  Iodide,  Squibb  g.  s.  bottle,  oz. 

Zinci  lodidum,  U.  S.  P.  VHIth,  Rev.  ZnI2.  White,  odorless, 
very  deliquescent  powder,  qf  sharp,  saline,  metallic  taste,  and 
turning  brown  on  exposure  to  light.  Readily  soluble  in  water, 
alcohol,  ether.  Alterative,  Antiseptic;  in  ulcerated  tonsils, 
gonorrhea,  etc.;  internally  in  scrofula,  syphilis,  etc.  Also 
used  as  Reagent.  Average  Dose:  1  grain  (0.065  Gm.).  Keep 
well  stoppered,  in  dry  place,  protected  against  light. 

©  Zinc  Oxide  Heavy,  Squibb  tin  Ib.        ;  |4  Ib. 

Zinci  Oxidum ;  Flowers  of  Zinc.  ZnO.  White,  odorless, 
tasteless  powder.  Insoluble  in  ordinary  solvents.  Drying  Anti- 
septic, Astringent  Dermic  and  Protective.  Zinc  oxide  absorbs 
carbon  dioxide  from  air;  hence  keep  container  well  closed. 

©  Zinc  Oxide  Light,  Squibb  tin  Ib.         ;  |4  Ib. 

1-oz.  sifter-top   tins,  per  doz. 

A  special  Squibb  product.  Of  exceptional  purity;  free  from 
lead,  and  stands  all  other  U.  S.  P.  tests;  very  bulky. 

Zinc  Phenolsulphonate,  Squibb  bottle,  oz. 

Zinci  Phenohulphonas  ;  Zinc  Sulphocarbolate.  Zn^oHyO.^ 
S)o.8H2O.  Of  greatest  purity  and  of  correct  chemical  con- 
stitution. Colorless,  odorless  crystals,  of  astringent,  metallic 
taste;  efflorescent.  1  Gm.  dissolves  in  1.6  mils  (Cc.)  water, 
1 .8  alcohol.  Antiseptic,  Astringent,  externally,  in  J/2  to  I 
percent,  solution,  in  gonorrhea,  ulcers,  etc.;  used  largely  as 
Intestinal  Antiseptic.  Average  Dose:  2  grains  (0.13  Gm.),  as 
tablets,  usually  in  combination  with  other  phenolsulphonates. 
(See  also  Tablets  Sulphocarbolates  Combined  [Part  II].) 

©  Zinc  Stearate,  Squibb  bottle,  Ib.         ;  1/4  Ib.         ;  oz. 

oz.  sifter-top  cans,  Scented  or  Unscented,  per  doz. 
Zinci  Slearas.     Fine,  white,  tasteless  powder;    faint,   fatty  odor. 
Yields    13    to    15.5    percent,    zinc    oxide.      Insoluble    in    water, 
alcohol    or   ether.      Vulnerary,    Antiseptic;    as    dusting    powder, 
snuff,  etc.,  pure  or  attenuated. 


SQUIBB'S  MATERIA  MEDICA       297 

®  Zinc  Sulphate,  Squibb  tin,  Ib.          ;  14  lb. 

Zinci  Sulphas  ;  White  Vitriol ;  Zinc  Vitriol.  ZnSO47H2O.  A 
highly  purified  salt.  White  granular  powder;  inodorous, 
very  efflorescent;  astringent,  metallic  taste.  I  Gm.  dissolves  in 
0.6  mil  (Cc.)  water,  2.5  glycerin;  insoluble  in  alcohol.  Astrin- 
gent, Antiseptic;  Emetic.  Externally  chiefly  in  0.5  to  2  percent, 
solutions  and  5  to  10  percent,  ointments.  Average  Dose:  eme- 
tic, 15  grains  (I  Gm.),  in  lukewarm  water.  Incompatible  with 
alkali  carbonates,  sodium  borate,  lead  acetate,  tannin,  vegetable 
astringents,  etc.  As  Zinc  Sulphate  Granulated  is  very  efflores- 
cent in  dry  air,  container  should  be  kept  well  closed  and  in 
cool  place.  (See  also  Reagents  [Part  IV] ;  Tablets  [Part  II].) 

Zinc  Sulphate  Dried,  Squibb  bottle,  Ib.         ;  '/4  Ib. 

ZnSO4.2HoO.  White  powder.  Soluble  freely  in  water. 
Action,  same  as  preceding;  but  as  this  dried  salt  contains  much 
less  water  of  crystallization  than  the  granular  (or  crystalline) 
sulphate  it  is  more  active.  Ordinary  Dose:  as  emetic,  10  grains 
(0!65  Gm..) 

Zinc  Sulphocarbolate.     See  Zinc  Phenolsulphonate. 

Zinc  Valerate,  Squibb  bottle,  oz. 

Zinci  Valeras;  Zinc  Valerianate.  White,  pearly  scales;  odor 
of  valeric  acid;  sweetish,  astringent,  metallic  taste.  1  Gm. 
dissolves  almost  completely  in  70  mils  (Cc.)  water,  22  alcohol. 
Loses  valeric  acid  on  exposure  and  becomes  less  soluble.  Used 
as  Nerve  Sedative.  Average  Dose:  2  grains  (0.13  Gm.). 

Zinc  Vitriol.        See  Zinc  Sulphate. 


Since  we  make  only  one  quality  of  each  product,  that  best 
suited  to  the  purposes  intended,  the  specification  "Squibb's" 
is  not  open  to  various  interpretations,  but  has  a  plain,  positive 
meaning.  When  ordering  or  prescribing,  specify  SQUIBB'S. 


PART  II 

Medicinal  Tablets 


SQUIBB'S  TABLETS  are  prepared  with  the 
greatest  care  and  skill,  contain  the  Squibb 
products  in  their  full  therapeutic  efficiency,  and 
meet  in  all  respects  the  high  standard  of  this  house  for 
purity,  uniformity  and  reliability. 

In  accordance  with  the  ethical  principles  of  the  Ameri- 
can Medical  Association,  only  pharmaceutical  titles  are 
used,  not  disease  names  or  designations  suggestive  of 
therapeutic  uses. 

The  cut  below  shows  the  shape  of  a  Tablet 
Triturate,  in  contradistinction  to  a  Compressed  Tab- 
let. Where  a  formula  is  carried  in  stock  in  more  than  one 
shape,  mention  of  this  fact  is  made  in  a  footnote;  and 
on  orders  where  no  specification  is  given,  the  form  regu- 
larly listed  will  be  supplied. 


COMPRESSED  TABLETS  TABLET  TRITURATES 

On  orders  for  Tablets  made  both  plain  and  coated,  the 
uncoated  will  be  supplied  unless  otherwise  specified. 

On  Tablets  listed  in  coated  form  the  coating  is  very 
soluble,  presents  no  hindrance  to  disintegration,  effectively 
masks  the  unpleasant  taste  of  the  ingredients,  and  prevents 
the  loss  of  volatile  constituents. 

Those  Tablets  which  contain  insoluble  medicaments, 
such  as  acetamlid,  the  bismuth  salts,  phenacetin,  salol,  and 
the  like,  may  be  relied  upon  to  disintegrate  as  soon  as  they 
reach  the  stomach  and  to  exhibit  full  therapeutic  activity, 
their  formulas  being  scientifically  constructed. 
298 


SQUIBB'S  MATERIA  MEDICA       299 

C.  T.  in  this  list  stands  for  Compressed  Tablets;  C.  C.  T.  for 
Chocolate  Coated  Tablets;  T.  T.  for  Tablet  Triturates;  G.  C.  T. 
for  Green  Coated  Tablets;  P.  C.  T.  for  Pink  Coated  Tablets; 
F.  C.  T.  for  Red  Coated  Tablets;  W.  C.  T.  for  White  Coated  Tablets. 

A  t  means  that  the  product  is  covered  by  the  Harrison  Anti- 
narcotic  Law,  and  therefore  must  be  ordered  on  the  official  blank. 

A  *  indicates  that  the  item  is  also  supplied  as  COMPRESSED 
Tablets.  However  unless  otherwise  specified,  T.  T.  will  be  supplied. 


Tablets  Absorbent  Digestive.         See    Tablets    Papain    and 
Charcoal    Compound. 

Tablets  Absorbent  Dyspepsia.       See     Tablets     Pepsin    and 
Charcoal  Compound. 

Tablets  Acetanilid  1  gr.,  Squibb 

Per  1000  Per  500  Per  100 

T.  T.. 

Antipyretic  and  Analgesic.  Acetanilid  is  prompt  and  certain  in 
its  action.  As  an  antipyretic,  it  is  used  in  sthenic  fevers,  with 
good  results  in  robust  patients,  but  in  prolonged  pyrexia  the 
cold  bath  is  less  liable  to  lead  to  complications.  As  an  anal- 
gesic, it  is  deemed  a  valuable  remedy  in  relieving  pain  of  a 
reflex  or  spasmodic  character.  Combined  with  caffeine,  it  is  a  fa- 
vorite remedy  in  migraine  and  neuralgic  pains  generally.  (See 
Tablets  Acetanilid  Compound.)  Occasionally,  through  incau- 
tious administration  or  weak  heart,  marked  cardiac  depression 
with  cyanosis  follows;  should  this  occur,  it  is  advised  to  place 
the  patient  in  a  recumbent  position,  apply  artificial  heat  and  give 
stimulants.  Dose :  for  children,  1  tablet  every  two  or  three 
hours;  for  adults,  1  to  5  tablets  every  two  or  three  hours  for 
not  more  than  three  doses. 

Tablets  Acetanilid  2  gr.,  Squibb 

Per  1000  Per  500  Per  1 00 

C.  T. 

Analgesic  and  Antipyretic.  Dose:  1  to  2  tablets,  every  hour 
until  three  or  four  have  been  taken. 

Tablets  Acetanilid  5  gr.,  Squibb 

Per  1000  Per  500  Per  100 

C.  T. 

Analgesic  and  Antipyretic.  Dose :  1  tablet  every  two  hours 
for  not  more  than  three  doses. 

Tablets    Acetanilid    and    Ammonium    Salicylate    Com= 
pound.      See  Tablets  Ammon,  Salicylate  and  Acetanilid  Comp. 


The  founder  of  the  House  of  Squibb,  Dr.  Edward  R.  Squibb, 
not  only  had  high  ideals,  but  lived  and  labored  for  them;  and, 
in  the  words  of  William  Miller  Bartlett,  "the  House  of  Squibb 
stands  today  as  a  living  monument  to  the  honor,  integrity,  zeal 
and  devotion  of  its  founder." 


300        SQUIBB'S  MATERIA  MEDICA 

f  Tablets  Acetanilid  and   Bromide  Compound,  Squibb 

(Neuralgic  Headache,  Dr.  Myers) 
C.  T.  Per  1000       Per  500       Per  100 


Acetanilid  1  gr. 

Sodium    Bromide  5  gr. 

Morphine  Sulphate  1/50  gr. 

Caffeine  Citrated  1/2  gr. 
Extract  Hyoscyamus 


These  tablets  are  used  in  mi- 
graine, headaches  due  to  con- 
gestion or  to  irritation  of  the 
sensory  nerves  and  neuralgic 
pains  in  general. 


Dose :  I  tablet,  repeated  in  half  an  hour  if  necessary,  but  not 
oftener  than  four  times  in  succession.  (NoTE. — In  the  use  of 
these  tablets  the  possible  formation  of  the  morphine  habit  should 
be  guarded  against.) 

Tablets  Acetanilid  and  Caffeine  Compound,  Squibb 

(Dr.  Hubbard) 

C.  T.  Per  1000  Per  500  Per  100 

Acetanilid  3*/2  gr.  ]        These  tablets  are  employed  as 

Caffeine  1  gr.  >•       an   analgesic   and   nerve   seda- 

Sodium   Bromide          7*/2  gr-  J        live,   chiefly   in    nervous  head- 
ache.    Dose:  2  tablets  with  a 
glass  of  water,  repeated  in   four  hours  if  required. 

Tablets  Acetanilid  and  Cannabis  Compound,  Squibb 

(Neuralgic  Improved) 
C.  T.  Per  1000  Per  500  Per  100 


Acetanilid  2  gr. 

Ext.  Cannabis  1/4  gr. 

Quinine  Sulphate  2  gr. 

Ext.  Hyoscyamus  l/o  gr- 

Acid  Arsenous  1/100  gr- 

Strychnine  Sulphate  i/eo  gr- 


This  combination  of  anal- 
gesics and  nervines  has  been 
employed  with  reputed  suc- 
cess in  the  treatment  of  mi- 
graine and  various  other  types 


of  neuralgia,  and  it  is  said 
to  be  particularly  useful  in 
cases  of  a  periodical  character,  whether  due  to  malarial  infection 
or  to  other  causes.  Care  should  be  taken  in  those  patients  who 
do  not  tolerate  acetanilid  well  or  who  show  an  idiosyn- 
crasy toward  cannabis.  Dose :  1  tablet,  repeated  in  half  an 
hour  if  required,  then  every  two  or  three  hours  until  the  con- 
dition is  relieved. 

Tablets  Acetanilid  and  Qelsemin  Compound,  Squibb 

C.  T.  Per  1000  Per  500  Per  100 

Acetanilid  2*/2  gr.  1        Antipyretic,      Analgesic      and 

Gelsemin  l/io  gr.  [•        Depressant.     The  well-known 

Caffeine  Citrated  1  gr.  J        action    of     acetanilid     is     here 

augmented  by  gelsemin.      The 

combination  has  been  used  with  reputed  success  in  neuralgia, 
pleurisy  and  pneumonia.  In  dysmenorrhea  and  ovarian  neural- 
gia it  is  credited  with  good  results,  but  is  deemed  especially 
useful  in  neuralgia  affecting  the  dental  branches  of  the  fifth 
nerve.  It  should  be  cautiously  administered,  as  certain  patients 
show  a  peculiar  idiosyncrasy  to  its  depressant  effects.  Dose :  1 
tablet  every  2  or  3  hours,  for  not  more  than  three  doses. 


SQUIBB'S  MATERIA  MEDICA        301 


f  Tablets  Acetanilid  and  Morphine  Compound,  Squibb 

(Analgesic  Compound) 
C.  T.  Per  1000  Per  500  Per  100 


Acetanilid  2  3/n  gr. 

Morphine  Sulphate  1/20  gr. 
Sodium  Salicylate  1 13/22  gr- 
Caffeine  5/oo  gr. 

Sodium  Bicarbonate  10/n  gr. 


-apsicum 


120  gr. 


Our  Tablets  Acetanilid  and 
Sodium  Salicylate  Compound 
have  generally  been  found  use- 
ful in  relieving  pain  of  a  re- 
flex or  spasmodic  character. 
In  some  cases,  however,  phy- 
sicians have  found  it  advis- 
able to  ado  small  doses  of  morphine  sulphate,  which  increase 
the  anodyne  effect,  and  a  little  capsicum,  to  stimulate  the  mucous 
membrane  of  the  stomach.  Dose:  1  or  2  tablets  with  water 
every  hour  or  two  until  relieved.  (NoTE. — These  tablets  should 
be  used  cautiously,  and  the  possibility  of  the  formation  of^ 
the  morphine  habit  guarded  against.) 

Tablets  Acetanilid  and  Quinine,  Squibb 

C.  T.  Per  1000  Per  500  Per  100 

Acetanilid  2!/2  gr.  \       This   formula  has  been   found 

Quinine    Sulphate        21/o  gr.  j       useful  in  the  treatment  of  re- 
flex  pains  of  neuralgic   origin 

in  sthenic  patients  where  there  is  no  cardiac  weakness.  It  pos- 
sesses marked  antipyretic  and  analgesic  properties,  and  good 
results  have  been  obtained  with  it  in  cases  of  migraine,  influenza 
and  other  painful  conditions.  We  call  particular  attention  to 
the  rapidity  with  which  these  tablets  and  similar  combinations 
here  listed  disintegrate  in  water  or  in  fluids  of  the  body,  thereby 
minimizing  any  possibility  of  cumulative  action,  as  each  dose 
promptly  produces  its  effect.  Dose :  1  tablet  with  water  every 
two  hours  for  three  or  four  doses,  then  every  four  hours. 

f  Tablets  Acetanilid  and  Quinine  Compound,  Squibb 

C.  T.  Per  1000         Per  500         Per  100 

Chocolate-coated   (C.  C.  T.) 

This  is  a  combination  of 
remedies  that  has  been  ex- 
tensively used  in  the  treat- 
ment of  grip  and  the  early 
stages  of  colds.  The  usual 
precautions  against  the  use  of 
acetanilid  must  be  observed  in 
its  administration,  although  the 

depressing  effect  is  somewhat  guarded  against  by  the  camphor 
and  quinine.  Its  action  as  a  sudorific  will  be  greatly  increased 
by  hot  drinks  during  the  treatment.  Dose :  1  tablet  every  2 
hours,  but  for  not  more  than  three  consecutive  doses. 


Acetanilid 

2gr. 

Quinine  Sulphate 

*/2  gr. 

Camphor 

!/4  gr- 

Capsicum 

*/4  gr. 

Podophyllin 

1/80  gr. 

Aconite.  Root 

1!-M  gr- 

Morphine  Sulphate 

1/120  gr.  . 

The  Squibb  Ideals  have  taken  concrete  form  in  the  Squibb 
Products;  these  are  universally  recognized  as  standards  of 
uniform  Purity  and  Efficacy,  that  is,  general  Excellence  and 
Reliability.  Specify  SQUIBB'S  when  prescribing  or  ordering. 


302        SQUIBB'S  MATERIA  MEDICA 

Tablets  Acetanilid  and  Salol,  Squibb 

C.  T.  Per  1 000  Per  500  Per  100 

Acetanilid  2*/2  gr-  \      The     acetanilid     acts     as     an 

Salol  2*/2  gr. )      Analgesic     and     Antipyretic ; 

.  the  salol  as  an  Antirheumatic 

and  Intestinal  Antiseptic.  Together  they  are  commonly  used  in 
acute  rheumatism,  gouty  attacks,  myalgia,  sciatica  and  neuralgic 
pains  of  rheumatic  origin.  In  the  early  stage  of  grip  and  sudden 
colds  they  have  been  found  to  relieve  pain  and  muscular  sore- 
ness promptly,  and  usually  without  bad  after-effect.  Great  care 
is  observed  in  all  of  Squibb's  tablets  to  prevent  decomposi- 
tion, and  to  present  the  medicaments  in  their  natural  activity, 
unchanged  by  the  process  of  manufacture;  hence  they  can  be 
relied  on  for  prompt  and  uniform  action.  Dose :  1  tablet  every 
hour  or  two  until  pain  and  fever  are  relieved.  Caution :  Tab- 
lets containing  salol  should  not  be  exposed  to  direct  sunlight  or 
kept  in  a  warm  place,  as  the  chemical  melts  at  about  106°  F. 

Tablets   Acetanilid   and   Sodium   Salicylate   Compound, 
Squibb  (Analgesic  No.  2) 

Per  1000  Per  500  Per  100 

C.  T. 

Acetanilid  21/o  gr.  "1       This  is  a  slight  modification  of 

Sodium  Salicylate  !3/4gr.  I  the  following  formula,  sodium 
Caffeine  1/4  gr.  f  sahcylate  being  substituted  for 

Sodium    Bicarbonate         1  gr.  J       the  strontium  salt.     The  indi- 
cations   for    its    use    and    the 
dose  are  the  same  as  those  of  the  next  combination. 

Tablets  Acetanilid  and  Strontium  Salicylate  Compound, 
Squibb  (Analgesic) 

Per  1000  Per  500  Per  100 

C.  T. 

Acetanilid  2*/2  gr- 1       Neuralgic        and        rheumatic 

Strontium  Salicylate  2  gr.  I  pains,  the  muscular  soreness 
Caffeine  */4  gr.  j  attending  grip,  headaches  and 

Sodium  Bicarbonate          1  gr.  J       reflex    pains   arising    from   de- 
layed    digestion     are     usually 

relieved  by  these  tablets.  They  act  as  an  analgesic  and  anti- 
pyretic, and  are  rarely  followed  by  bad  after-effects.  Dose : 
1  or  2  tablets  every  three  or  four  hours  until  relieved,  but  not 
oftener  than  four  times  in  succession. 

Tablets  Acetanilid  Compound,  Squibb 

(Migraine) 

C.  T.  Per  1000  Per  500  Per  100 

Acetanilid  2  gr.  ~|       This    formula    is    used    in    the 

Camphor  Monobrom.  1/o  gr.  j-  treatment  of  neuralgic  pains, 
Caffeine  1/4  gr.  J  particularly  in  pains  of  a  re- 

flex   or    spasmodic    character; 
hence  it  is  most  frequently  employed   for   the  prompt  relief  of 


SQUIBB'S  MATERIA  MEDICA        303 

Tablets  Acetanilid  Compound,  Squibb  (Cont.) 

headache.  The  rapidity  with  which  the  tablets  disintegrate  in- 
sures prompt  therapeutic  action  and  prevents  cumulative  effect. 
Dose :  I  or  2  tablets  with  water,  every  hour  if  necessary,  for 
four  or  five  doses;  it  is  deemed  advisable  to  discontinue  the 
tablets  after  the  fifth  consecutive  dose. 

Tablets  Acetanilid  Compound  No.  2,  Squibb 

(Migraine  No.  2) 

Per  1000  Per  500  Per  100 

C.  T. 

Acetanilid  3  gr.  "I       This    is  a   modification  of   the 

Camphor  Monobrom.  2  gr.  j-  preceding  formula,  the  quantity 
Caffeine  1/2  gr.  J  of  each  of  the  ingredients  be- 

ing increased.    It  is  used  under 

the  same  conditions.  Dose:  1  tablet  every  hour  for  three 
doses,  then  every  2  or  3  hours  until  the  condition  is  relieved. 

Tablets  Acetanilid  Compound  No.  3,  Squibb 

(Migraine  No.  3) 

Per  1000     Per  500     Per  100 
C.  T. 

Acetanilid  31/2  gr.  "j       These     tablets    are    used"    for 

Caffeine  1/2  gr.  J-      promptly       controlling       reflex 

Sodium   Bicarbonate          1  gr.  J       pains  arising  from  disturbance 

of  nerve  function.  They  com- 
bine the  analgesic  and  antipyretic  action  of  acetanilid  with  the 
antacid  properties  of  sodium  bicarbonate.  They  have  been 
found  useful  in  nervous  and  sick  headache  due  to  mental 
strain  or  disordered  digestion,  and  for  the  relief  of  neuralgia 
and  reflex  pains  with  fever.  Dose :  1  tablet  with  water  every 
hour  if  necessary  for  three  doses.  If  not  relieved  after  the 
third  dose,  it  is  advised  to  wait  three  hours  before  resuming. 

Tablets  Acetanilid  Compound  No.  4,  Squibb 

(Migraine  No.  4) 

Per  1000  Per  500  Per  100 

C.  T. 

Acetanilid  3  gr.  1       These  tablets  are  more  power- 

Caffeine  1/9  gr.  1       ful    than    those   of   the    regular 

Camphor  Monobrom.  1  gr.  f  Acetanilid  Compound  formu- 
Sodium  Bicarbonate  1  gr.  J  la.  They  are  used  chiefly  in 

the      treatment     of      neuralgia 

and  spasmodic  pains  in  robust  patients.  Dose :  1  tablet  with 
water  every  hour  for  three  or  four  doses. 


The  Squibb  Label  on  a  package  is  a  positive  guaranty  for  .the 
uniform  Purity  and  Reliability  of  the  product.  We  make  only 
ONE  quality:  the  SQUIBB  quality;  and  our  prices  are  as  low 
as  they  can  be  made  for  that  quality.  Specify  SQUIBB'S. 


304        SQUIBB'S  MATERIA  MEDICA 

Tablets  Acetanilid  Compound  Improved,  Squibb 

(Migraine  Improved) 

Per  1000  Per  500  Per  100 

C.  T. 


Acetanilid  2l/2  gr. 

Camphor  Monobrom.     ^-{2  gr. 
Sodium   Salicylate  1  gr. 

Ext.  Hyoscyamus  1/s  gr. 

Tincture  Gelsemium     2  min. 


These  tablets  are  employed  to 
relieve  headaches  and  neural- 
gic pains  in  gouty  and  rheu- 
matic subjects.  Dose :  1  to  3 
tablets  with  water,  repeated  in 


half  an  hour  if  not  relieved; 
then  1   tablet  every  hour  or  two  until  pain  is  controlled. 

Tablets  Acetanilid  Compound  for  Children,  Squibb 

Per  1000  Per  500  Per  100 

T.  T. 

For  the  relief  of  headache 
and  neuralgia  in  children  and 
weak  individuals.  Dose :  I 
to  3  tablets  every  hour  for 
four  doses  if  needed. 


Acetanilid  ?/io  gr. 

Caffeine  Citrated          1/10  gr. 
Sodium   Bicarb.  1/5  gr. 

Saccharin  VlOO  gr. 

Wintergreen  Flavor  !/5o  min. 


Tablets  Acetphenetidin  Igr.,  Squibb 

(Phenacetin)  Per    1000         Per  500         Per   100 

T.  T. 

Acetphenetidin  is  chemically  and  physiologically  identical  with 
Phenacetin.  It  reduces  fever,  allays  pain  and  is  widely  used 
in  headache,  neuralgia  and  reflex  pains  generally.  Although 
regarded  as  one  of  the  safest  remedies  of  its  kind,  occasionally 
it  causes  cardiac  depression  with  cyanosis.  Should  this  occur, 
the  patient  is  placed  in  a  recumbent  position,  stimulants  are 
administered,  and,  if  necessary,  artificial  heat  applied.  Tablets 
Acetphenetidin  Squibb  disintegrate  more  quickly  than  cachets, 
capsules,  or  pills,  and  they  are  more  convenient  than  powders. 
Dose  (for  children)  :  1  or  2  tablets  every  two  or  three  hours. 

Tablets  Acetphenetidin  2  gr.,  Squibb 

(Phenacetin)  Per   1000         Per  500         Per   100 

C.  T. 
Dose :    1    or  2  tablets  every  two  or   three  hours. 

Tablets  Acetphenetidin  5  gr.,  Squibb 

(Phenacetin)  Per    1000          Per  500          Per   100 

C.  T. 

Dose :  1  to  3  tablets  with  water,  repeated  as  necessary.  In 
weak  heart,  brandy  or  whisky  is  usually  administered  if  signs 
of  depression  occur. 


SQUIBB'S  MATERIA  MEDICA        305 

Tablets  Acetphenetidin  and  Quinine,  Squibb 

(Phenacetin  and  Quinine)      Per   1000         Per  500         Per   1 00 

C.  T. 

Acetphenetidin  21/o  gr.  1      This  combination  is  similar  in 

Quinine    Sulphate        2^/2  gr.  j       therapeutic    action    to    Tablets 

Aoetanilid  and  Quinine.  How- 
ever, acetphenetidin  is  generally  regarded  as  being  less  liable 
than  acetanilid  to  cause  cardiac  depression  while  fully  as  effi- 
cient. Dose :  I  or  two  tablets  repeated  in  an  hour  if  neces- 
sary, then  at  intervals  of  three  or  four  hours  until  relieved. 

Tablets  Acetphenetidin  and  Salol.       See  Tablets  Salol  and 
Acetphenetidin. 

Tablets  Acid  Acetylsalicylic  5  gr.,  Squibb 

(Aspirin)  Per  1000         Per  500         Per  100         Per  25 

C.  T. 

These  tablets  are  carefully  made  in  order  to  avoid  decompo- 
sition of  the  chemical  during  manufacture.  They  disintegrate 
at  once  in  water,  and  are  free  from  any  acetic  odor  (indicative 
of  decomposition).  They  are  used  as  an  Antirheumatic,  In- 
testinal Antiseptic  and  Analgesic,  in  the  same  classes  of  cases 
in  which  salicylic  acid  and  the  salicylates  are  indicated.  Dose: 
1  to  4  tablets  with  water,  several  times  a  day.  Keep  the  bottle 
well  stoppered  and  in  a  dry  place. 

*  Tablets  Acid  Arsenous  1/100  gr.,  Squibb 

Per  1000  Per  500  Per  100 

T.  T. 

Acid  arsenous  affects  the  blood,  the  nerves  and  the  skin.  Under 
its  use  nutrition  generally  improves,  bodily  weight  increases,  and 
the  skin  becomes  soft  and  smooth.  It  thus  acts  as  an  Alterative 
and  Tonic,  and  is  employed  in  anemia,  malarial  cachexia, 
obstinate  skin  diseases,  neuralgia  and  in  controlling  the  nervous 
symptoms  in  epilepsy  and  chorea.  Its  use  creates  a  tolerance, 
yet  it  is  an  active  poison  and  should  be  administered  with  cau- 
tion. In  case  of  reddening  of  the  eyelids  or  pain  or  fulness 
of  the  stomach,  it  is  advised  to  discontinue  its  use  until  these 
symptoms  abate,  and  then  resume  it.  Dose :  1  tablet  after  each 
meal,  increasing  gradually  and  cautiously  until  the  desired 
effect  is  obtained. 

*  Tablets  Acid  Arsenous  1/30  gr.,  Squibb 

T.  T.  Per  1 000  Per  500  Per  100 

Dose :  1  tablet  three  times  a  day,  after  meals,  in  skin  diseases, 
neuralgia,  epilepsy,  chorea,  etc.,  and  as  a  tonic  in  debility  and 
malarial  cachexia. 


Squibb's  Tablets  are  made  from  the  Squibb  quality  of  ingredients 
and  by  improved  processes  that  insure  accurate  dosage  and 
rapid  and  complete  disintegration  or  solution  in  the  system, 
hence  prompt  and  full  therapeutic  effect.  Specify  SQUIBB'S. 


306        SQUIBB'S  MATERIA  MEDICA 

f  Tablets    Acid    Benzoic    and    Belladonna    Compound, 
Squibb  (Throat,  Dr.  Quinlan) 

C.  T.  "Per  1000  Per  500  Per  100 

Acid  Benzoic  J/5  gr.  1       These  tablets  are  employed  in 

Tr.  Bellad.  U.S.P.*90  1  min.  I  irritated  and  congested  condi- 
Paregoric  10  min.  f  lions  of  the  pharynx  and  lar- 

Extract  Licorice  q.  s.  j      ynx,  where   Joss  of  voice  and 

cough  are  prominent  symptoms. 

They  are  palatable  and  do  not  usually  interfere  with  digestion 
unless  they  are  taken  in  excessive  quantities  or  for  prolonged 
periods.  Dose :  1  tablet  allowed  to  dissolve  on  the  tongue 
every  two  to  four  hours. 

Tablets  Acid  Boric  1  gr.,  Squibb 

(For   Urine   Preserving) 
T.  T.  Per  1000  Per  500  Per  100 

These  tablets  are  made  without  sugar  or  any  other  base,  and 
consist  wholly  of  the  Squibb  quality  of  boric  acid.  They  are 
designed  for  use  in  preserving  specimens  of  urine  intended  for 
analysis,  and  are  employed  and  recommended  for  this  purpose 
by  the  medical  staff  of  many  insurance  companies.  In  winter, 
1  tablet  added  to  1  fluidounce  of  urine  is  ordinarily  sufficient 
to  preserve  it,  but  in  warm  weather  3  tablets  are  usually  required 
for  each  fluidounce  of  urine. 

Tablets  Acid  Boric  5  gr.,  Squibb 

C.  T.  Per  1000  Per  500  Per  100 

Employed  as  an  Intestinal  and  Vesical  Antiseptic,  in  septic 
and  catarrhal  inflammatory  conditions  of  the  digestive  and 
genito-urinary  organs.  In  ammoniacal  cystitis  the  internal  ad- 
ministration of  boric  acid  usually  gives  prompt  relief,  when 
employed  in  connection  with  irrigation  of  the  bladder;  in  de- 
layed digestion  with  fermentation  of  food  and  diarrhea,  it  is 
aiso  used  for  its  mild  antiseptic  properties  with  good  results. 
These  tablets  are  prepared  for  internal  administration,  but 
they  may  be  used  also  for  making  antiseptic  solutions; 
they  break  up  quickly  in  water,  and  yield  a  perfectly  clear  so- 
lution. Dose :  1  to  3  tablets  three  or  four  times  daily. 

Tablets  Acid  Boric  and  Buchu  Compound,  Squibb 

(Cystitis) 
C.  T.  Per  1000  Per  500  Per  100 


Acid  Boric  2 


gr. 


Extract  Buchu  1  gr. 

Potassium  Bicarbonate     2  gr. 
Extract  Dog-Grass  1  gr. 

Extract  Cornsilk  1/2  gr. 

Extract  Hydrangea       1/^  gr. 
Atropine   Sulphate      VoOO  gr- 


Boric  acid  prevents  fermenta- 
tion of  urine.  Potassium  bi- 
carbonate neutralizes  exces- 
sive acidity.  Buchu  acts  as  a 
stimulant  to  the  mucous  mem- 
branes of  the  genito-urinary 
organs,  and  in  combination 


with  dog-grass,  cornsilk  and 
hydrangea,  is  said  to  cause  an  increased  flow  of  urine  and  to 
lessen  the  pain  and  frequent  desire  to  urinate.  Atropine  acts  as 


SQUIBB'S  MATERIA  MEDICA        307 

Tablets  Acid  Boric  and  Buchu  Compound,  Squibb 
(Continued) 

an  antispasmodic.  These  tablets  are  employed  in  cystitis,  as 
well  as  in  gonorrhea.  Dose :  1  tablet  every  three  hours,  be- 
tween meals,  with  a  large  glass  of  water. 

Tablets  Acid  Boric  and  Zinc  Sulphate,  Squibb 

C.  T.  Per  1000  Per  500  Per  100 

Acid  Boric  5  gr.  1      These    tablets    will    be    found 

Zinc  Sulphate  */4  gr.  j      very    convenient     for    use    in 

ophthalmic   and  genito-urinary 

work.  They  disintegrate  rapidly  and  yield  a  perfectly  clear 
solution.  An  Antiseptic  and  mildly  Astringent  solution  may 
be  made  by  dissolving  2  to  4  tablets  in  1  fluidounce  of  sterile 
water.  Hot  water  hastens  solution.  Keep  the  bottle  well- 
corked.  Dispense  in  glass. 

Tablets     Acid     Salicylic     and     Colchicum     Compound, 
Squibb  (Antirheumatic   No.  2) 

C.  T.  Per  1000  Per  500  Per  100 

Acid  Salicylic  3  gr.  ]       The    acid    salicylic    and     so- 

Wine  Colchicum  Seed  1  min.  }•  dium  bicarbonate  in  these 
Sodium  Bicarbonate  2*/2  gr.  J  tablets  have  not  interacted,  but 

do  so  in   the   system,   or  when 

placed  into  water,  with  the  production  of  nascent  sodium  sali- 
cylate.  In  dispensing  these  tablets  if  the  effervescent  nature  of 
the  mixture  is  deemed  of  any  importance,  they  should  be  put 
up  in  glags  only.  Dose :  1  tablet  after  each  meal  and  at  bed- 
time in  chronic  cases;  more  frequently  in  acute  cases. 
Tablets  Aconite  Fluidextract  1  min.,  Squibb 

T.  T.  Per  1000  Per  500  Per  100 

Aconite  is  used  to  control  inflammation  with  high  arterial  ten- 
sion, and  to  reduce  fever.  It  quiets  the  heart,  reduces  the 
force  and  frequency  of  the  pulse,  lessens  the  number  of  respira- 
tions, increases  the  action  of  the  skin,  and  allays  restlessness. 
In  the  acute  attacks  of  sthenic  fevers,  tonsillitis,  ulcerative  sore 
throat  and  sudden  colds,  it  is  regarded  as  a  valuable  and  reliable 
remedy,  but  it  must  be  used  with  caution.  In  overdoses  it  is  an 
.  active  poison.  Tablets  Aconite  Squibb  represent  the  full  po- 
tency of  the  best  German  aconite  root,  carefully  assayed  and 
standardized.  Dose:  1  tablet  dissolved  in  ten  (10)  tablespoon- 
fuls  of  water  and  1  tablespoonful  given  every  hour  until  symp- 
toms improve,  stirring  carefully  before  each  dose.  For  the 
convenience  of  physicians  who  are  accustomed  to  use  Tincture 
Aconite  in  place  of  the  fluid-extract,  we  would  state  that  the 
latter  is  ten  times  stronger  than  the  present  official  tincture.  One 
tablet  of  Fluidextract  Aconite  1  minim  Squibb  dissolved  in  10 
teaspoonfuls  of  water  would  represent  the  aconite  strength  of  10 
minims  of  the  tincture;  of  this,  each  teaspoonful  would  be 
equivalent  to  1  minim  of  Tincture  Aconite. 

This  house  supplies  only  one  quality  of  each  product:  that  best 
suited  to  the   purposes   intended.     The   specification      Squibb  s 
is    not  open    to    various    interpretations;     it    has  a     plain,     posi- 
tive meaning.      Therefore,  when   prescribing,   specify  SQUIBB  S. 


308        SQUIBB'S  MATERIA  MEDICA 

":  Tablets  Aconite  and  Belladonna,  Squibb 

T.  T.  Per  1 000  Per  500  Per  100 

Tr.  Aconite  U.S.P/90  !/2  min.  |  The  recognized  action  of 
Tr.  Bellad.  UJS.P/90  i/2  min.  )  belladonna  in  supporting  the 

heart     and     stimulating     the 

respiratory  centers  is  here  taken  advantage  of  to  lessen  the  de- 
pressing effect  of  the  aconite.  Together  the  two  remedies  should 
make  an  excellent  combination  in  the  treatment  of  inflamma- 
tory conditions,  with  rapid  pulse,  hurried  respiration  and  fever. 
Prompt  results  usually  follow  their  administration  in  sore 
throat  and  in  fevers  associated  with  bronchial  inflammation. 
Dose:  for  children,  1  tablet  dissolved  in  10  teaspoonfuls  of 
water,  and  given  in  teaspoonful  doses  every  twenty  minutes 
until  fever  abates;  for  adults,  1  tablet  every  hour. 

Tablets  Aconite  and  Belladonna  Compound,  Squibb 

(Fever  No.  2,  Dr.  T.  G.  Davis) 

T.  T.  Per  1 000  Per  500  Per  100 

Tr.  Aconite  U5.P/90  Vs  gr- 1  These  tablets  are  carefully 
Tincture  Bryonia  Vio  min.  }•  prepared  from  the  assayed 

Tr.  Bellad.  U.S.P.'90  1/io  min.  J       tinctures    and    represent    all 

their  potency  in  a  convenient 

form.  They  are  used  in  febrile  conditions  marked  by  rapid 
pulse  and  dry  skin;  in  tonsillitis  and  bronchial  inflammation; 
in  the  eruptive  fevers  (particularly  in  children);  etc.  Dose:  for 
children,  1  tablet  every  2  hours;  for  adults,  2  to  4  tablets  at 
a  dose.  Allow  the  free  use  of  water.  % 

*Tablets  Aconite  and  Belladonna  Compound  No.  2, 
Squibb         (Bronchitis   No.  2,  Acute,  Dr.  T.  G.  Davis) 

T.  T.  Per  1000  Per  500  Per  100 


Tr.  Aconite  U.S.P/90  l/5  gr. 
Tr.  Bellad.  U5.P'.90  1/10  mm. 
Tincture  Bryonia  1/ioo  min. 
Antimony  Sulphide  VlOO  gr. 
Potassium  Dichrom.  -Vioo  gr- 


in the  early  stage  of  colds 
with  fever  and  scanty  expec- 
toration, this  formula  is  said 
to  be  very  efficient.  Dose  :  1 
tablet  every  half  hour  until 


secretions  act  normally,  then 
every  two  hours;  in  chronic  bronchitis  in  delicate  patients  or 
in  the  aged,  1  tablet  three  or  four  times  a  day. 

f*Tablets   Aconite   and    Belladonna    Compound    No.    4, 
Squibb  (Follicular  Tonsillitis) 

T.  T.  Per  1000  Per  500  Per  100 


Tr.  Aconite  US.P.'90  l/5  gr. 
Tr.  Bellad.  US.P.'90  1/10  min. 
Tincture  Bryonia  ^Iw  mm. 

Mercury  Iodide  Red  Vioogr. 
Morphine  Sulphate  VlOO  gr- 
Sodium  Salicylate  1  gr. 

Wmtergreen  Flavor       l/^o  mm. 

feet,  and  with  bryonia,  a  mu- 
cous membrane  stimulant,  it  is  said  to  act  remarkably  well,  allay- 


The  power  of  aconite  to  con- 
trol inflammation  and  to  sub- 
due fever  is  easily  demon- 
strated in  the  early  stage  of 
tonsillitis.  In  combination 
with  belladonna,  which 
counteracts  its  depressing  ef- 


SQUIBB'S  MATERIA  MEDICA       309 

f*Tablets   Aconite   and   Belladonna   Compound   No.   4, 
Squibb  (Continued) 

ing  the  pain  and  inflammation,  relieving  the  muscular  soreness, 
quieting  the  heart  and  reducing  the  fever.  Red  mercuric  iodide 
in  small  and  repeated  doses  is  believed  to  exert  a  positive 
influence  over  the  mucous  membrane  in  tonsillitis,  and  to  re- 
lieve the  inflammation,  swelling  and  pain.  Morphine  acts  as 
an  anodyne  and  adds  to  the  diaphoretic  action  of  the  aconite. 
Sodium  salicylate  serves  to  counteract  the  rheumatic  tendency, 
which  is  often  seen  in  recurrent  attacks.  Dose :  1  tablet,  on 
the  back  of  the  tongue,  every  fifteen  minutes  for  four  doses, 
then  every  hour  until  relieved. 

*  Tablets  Aconite  and  Bryonia  Compound,  Squibb 

(Dr.  Judd) 
Per  1000  Per  500  Per  100 

T.  T. 

Tr.  Aconite  UJ5.P.  '90  1  min.  1       This      combination      is 

Tr.  Gelsemium  U.S.P.'90  l7/gmin.  V  largely  used  in  the 
Tincture  Bryonia  1  ^/4  mm.  J  treatment  of  inflamma- 

tory conditions  at- 
tended by  dry,  spasmodic  cough ;  in  the  early  stage  of 
fevers  with  high  arterial  tension  and  rapid,  full  pulse;  in 
sore  throat,  acute  bronchitis,  pleurisy,  etc.  Dose:  10  tablets 
dissolved  in  8  tablespoon fuls  of  water  and  a  teaspoonful  given 
every  hour,  carefully  stirring  the  mixture  before  giving  each 
dose ;  children  in  proportion.  These  tablets  are  prepared  so 
that  they  disintegrate  quickly  in  water,  and  they  will  be  found 
very  convenient  for  use  at  the  bedside.  They  represent  the 
full  potency  of  the  standardized  tinctures  wholly  uninjured  by 
the  process  of  manufacture.  The  tincture  of  aconite  employed 
is  3 1/2  times,  and  the  gelsemium  tincture  lj/2  times,  the  strength 
of  the  present  U.  S.  P.  articles. 

f  Tablets  Aconite  and  Calomel  Compound,  Squibb 

(Cold  No.  5) 

Per  1000  Per  500  Per  1 00 

T.  T. 

Tr.  Aconite  U.S. P.'90  1  min.  "I  This  is  a  favorite  combination 
Calomel  1/6  gr.  [  with  many  physicians  in  the 

Atropine  Sulphate  VoOO  gr-  f  treatment  of  cold  accompanied 
Morphine  Sulphate  ^-JZQ  gr.  J  by  fever  and  more  or  less 

bronchial   and  hepatic  conges- 
tion.    It  induces  free  action  of  the  skin,   allays  pain   and  rest- 


The  prices  of  the  Squibb  Products  are  in  all  instances  as  low  as 
the  quality  and  quantity  of  ingredients  and  the  expense  of  man- 
ufacture allow.  They  include  containers,  packing  and  boxing.  When 
ordering  or  prescribing  medicinal  products,  specify  SQUIBB'S. 


3/0       SQUIBB'S  MATERIA  MEDICA 

f  Tablets  Aconite  and  Calomel  Compound,  Squibb 
(Continued) 

lessness,  quiets  the  pulse,  and  relieves  plethora.  Its  use  in  the 
early  stages  of  cold  will  usually  bring  about  a  rapid  ameliora- 
tion of  the  symptoms  and  frequently  cut  short  an  attack.  As 
the  morphine  somewhat  interferes  with  the  laxative  action  of 
the  calomel,  in  some  cases  it  is  well  to  follow  with  a  saline 
laxative  after  the  administration  of  the  third  tablet.  Dose:  1 
tablet  every  hour  for  two  or  three  doses,  then  every  2  or  3 
hours  for  three  doses  more.  Continue  in  gradually  decreasing 
doses  until  the  nasal  discharge  ceases.  (NOTE:  These  tab- 
lets should  be  used  cautiously,  and  the  possibility  of  the  for- 
mation of  the  morphine  habit  guarded  against.) 

f  Tablets  Aconite  and  Camphor  Compound,  Squibb 

(Cold  No.  4,  Dr.  Coil) 

Per  1000  Per  500  Per  100 

T.  T. 

Aconite  i/lO  gr.  1       These  tablets  have  been  found 

Camphor  !/10  gr.  [      useful    in    the    early    stage    of 

Opium    Powd«red        Vio  gr<  f      "cold      in      the     head"     with 
Potassium    Nitrate        l/io  gr.  J       coryza.     Their  action  is  sudo- 
rific,  refrigerant  and   diuretic. 

Taken  at  the  onset  of  an  attack  they  usually  cause  an  abatement 
of  the  sneezing  and  febrile  symptoms  and  frequently  abort  the 
attack.  Dose:  10  tablets  in  water  at  bedtime,  or  1  tablet  every 
hour  for  ten  doses  during  the  day.  Quinine  in  tonic  doses  is 
reported  often  to  be  beneficial  during  the  treatment.  (NoTE: 
— In  the  use  of  these  tablets  the  possibility  of  the  formation  of 
the  opium  habit  should  be  borne  in  mind  and  guarded  against.) 

Tablets  Aconite  and  Camphor  Compound  No.  2,  Squibb 
(Rhinitis,  Infants',  Dr.  R.  B.  Kimball) 

Per  1000  Per  500  Per  100 

T.  T. 

Tr.  Aconite  U5.P/90  V-l  min-  ]  Antierrhine.  The  well-known 
Camphor  VlO  gr-  f  antipyretic  and  sedative  ac- 

Tr.  Bellad.  U.S.P.'90    1/4  min.  J       tion    of    aconite    and    bella- 
donna  is   here   supplemented 

by  the  antispasmodic  and  sedative  effect  of  camphor,  which  is 
held  in  repute  in  the  treatment  of  coryza,  especially  at  the  onset. 
The  tinctures  of  aconite  and  belladonna  used  in  these  tablets  are 
prepared  from  the  best  quality  of  the  ass_yed  drugs  and  care- 
fully evaporated  at  low  temperature;  the  resultant  extract  is 
mixed  with  sugar  of  milk  and  incorporated  in  the  tablets.  In 
this  way  the  therapeutic  action  of  the  drugs  is  not  changed  or 
destroyed.  Dose :  1  tablet  with  water  or  diffused  in  water  to 
which  about  five  drops  of  glycerin  may  be  added,  every  hour 
until  relieved. 


SQUIBB'S  MATERIA  MEDICA        311 
Tablets  Aconite  and  Colchicum  Compound,  Squibb 

(Sciatica) 

T.  T.  Per  1000  Per  500  Per  100 

Tr.  Aconite  U.S.P/90  3/4  min.  1  Deranged  functions  of  th« 
Tr.  Colchic,  U.S. P. '90  3/4  min.  I  nerves  and  secretory  organs 
Tr.  Bellad,  U.S.P.'903/4  min.  f  are  the  indications  for  these 
Tincture  Cimicifuga  3/4  min.  J  tablets,  which  act  as  a  seda- 
tive to  the  nerves  and  relieve 

pain.  By  their  action  upon  the  circulation  they  tend  to  improve 
nutrition  of  the  nervous  system  and  aid  in  the  elimination  of 
waste  products  through  the  skin,  the  kidneys  and  the  bowels.  In 
sciatica  their  effect  is  usually  prompt.  Dose:  2  tablets  every 
three  hours  until  pain  is  relieved. 

*  Tablets  Aconite  and  Mercury  Compound,  Squibb 

(Tonsillitis) 

T.  T.  Per  1000  Per  500  Per  100 

Tr.  Aconite  U5.P.'90  Vo  min.  1  Aconite  given  in  the  early 
Mercury  lod.  Red  VlOO  gr-  I  stage  of  tonsillitis,  when  the 
Tincture  Bryonia  VlO  min.  f  skin  is  hot  and  dry,  causes  a 
Tr.  Bellad,  U.S. P. '90  1/io  min.  J  copious  perspiration,  relieves 

the    chilliness    and    muscular 

soreness,  and  reduces  the  inflammation  and  fever.  Bella- 
donna lessens  its  depressant  effect.  Bryonia  acts  as  a  stimu- 
lant to  the  mucous  membrane.  Red  iodide  of  mercury  re- 
duces the  swelling  and  inflammation.  Dose:  1  tablet,  on  the 
tongue,  every  twenty  minutes  for  three  doses,  then  every  half 
hour  for  two  doses;  afterwards  at  hourly  intervals  until  the  pain 
and  inflammation  are  relieved. 

Tablets  Aconitine  1/500  gr.,  Squibb 

C.  T.  Per  1000  Per  500  Per  100 

Aconitine  is  used  for  neuralgic  and  sciatic  pains,  and  is  con- 
sidered especially  useful  in  trifacial  neuralgia.  Some  patients 
show  an  idiosyncrasy  to  its  use,  and  it  should  therefore  be  given 
cautiously,  more  particularly  where  weak  heart  exists,  beginning 
with  the  smaller  dose  and  gradually  increasing  until  the  systemic 
effect  is  observed.  Dose :  1  tablet  every  three  or  four  hours  until 
effective. 

Tablets  Agaricin  1/10  gr.,  Squibb 

C.  T.  Per  1000  Per  500  Per  100 

Agaricin  (Agaricic  Acid)  appears  to  act  directly  upon  the 
sweat  glands  and  not  through  the  nerve  centers.  It  has  been 
used  for  the  excessive  sweating  of  gouty  patients,  but  it  is  prin- 
cipally employed  to  control  night  sweats  in  phthisis.  The  action 
of  agaricin  is  slow,  four  or  five  hours  elapsing  before  its  effects 
are  apparent;  hence  the  dose  should  be  timed  accordingly. 
Dose:  1  tablet,  after  supper,  repeated  at  bedtime  if  required. 


If  difficulty  is  experienced  in  procuring  any  Squibb  product, 
in  the  original  packages  here  listed,  please  notify  us;  we 
shall  see  that  your  wants  are  met  promptly  and  satisfactorily. 


312        SQUIBB'S  MATERIA  MEDICA 

Tablets  Agaricin  Compound,  Squibb 

(Antihydrotic ;    Night  Sweat) 
C.  T.  Per  1000  Per  500  Per  100 

Agaricin  1/12  gr-  ]       These    tablets    are    used    for 

Picrotoxm  i/CO  gr.  V      controlling   excessive    sweating 

'Atropine  Sulphate  1/i20  gr.    J      in    phthisis    and    in    rheumatic 

and  gouty  subjects.     Dose:   1 
tablet  at  bedtime,  repeated  in  two  hours  if   required. 

Tablets  Aiken's  Tonic.     See  Tablets  Quinine  and  Iron  Comp. 

Tablets  Aiken's  Tonic  Laxative.     See  Tablets  Quinine  and 
Iron  Compound  with  Cascarin. 

Tablets  Aloes  and  Mastic,  Squibb 

(Dinner)  Per   1000         Per  500         Per  100 

Chocolate-coated  (C.  C.  T.) 

Aloes  Purified  2  gr.  1      This  is  a  favorite  laxative  in 

Mastic  1/2  gr.  f      dyspepsia   with    habitual    con- 

Red  Rose  1/2  gr.  J       stipation.      Aloes    acts    chiefly 

upon     the    lower    bowel     and 

rectum;  its  action  is  slow,  but  not  lessened  by  habitual  use. 
Where  not  contraindicated  by  piles,  these  tablets  are  considered 
a  useful  laxative  that  may  be  taken  as  long  as  constipation  exists. 
Dose :  I  or  2  tablets  after  dinner,  or  1  to  3  tablets  at  bedtime. 

Tablets  Aloes,  Mercury  and  Podophyllin,  Squibb 

(Triplex)  Per   1000         Per  500         Per   100 

C.  T. 

Chocolate-coated  (C.  C.  T.) 

Aloes  Purified  2  gr.  1     The   same  combination  as  the 

Mercury   Mass  1    gr.    f    N.   F.    IV   pills   of    the   same 

Podophyllin  ^4   gr-  J     name.     It  is  used  in  constipa- 

tion   with    hepatic    congestion. 
Dose :    1    or   2   tablets  with  water,   after   meals   or   at   bedtime. 

*  Tablets  Aloin  and  Belladonna*  Compound,  Squibb 

T.  T.  Per  1000        Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 

Aloin  1/5  gr.  "I       Aloin    is    conceded    to    be    a 

Extract  Belladonna  1/g  gr.  >  valuable  remedy  in  constipa- 
Strychnine  Sulphate  1/co  gr.  J  lion,  its  action  being  almost 

wholly    confined    to    the    large 

intestine  and  rectum,  but  also  possessing  a  slight  stimulating  effect 
upon  the  liver.  The  addition  of  the  belladonna  and  strychnine 
serves  to  increase  peristalsis,  overcome  muscular  atony  and  pre- 
vent griping  and  tenesmus.  The  formula  is  deemed  an  excellent 
one  in  habitual  constipation  attended  with  indigestion  and 
hepatic  torpor;  one  particularly  adapted  for  persons  of  seden- 
tary habit.  Its  use,  it  is  maintained,  may  be  continued  without 
debilitating  the  bowels.  Dose:  1  or  2  tablets  at  night,  followed 
by  a  glass  of  water  and  repeated  the  following  morning  if 
necessary. 


SQUIBB'S  MATERIA  MEDICA        313 

Tablets  Aloin  and  Belladonna  Compound  No.  2,  Squibb 

Per  1000       Per  500       Per  100 
T.  T. 
Chocolate-coated  (C.  C.  T.) 

Aloin  */5  gr- 1       This  tablet  is  similar  in  corn- 

Extract    Belladonna       !/8  gr.  j-      position     and     action     to     the 
Strychnine  Sulphate  1/i20  gr-  J       preceding    formula,    but    con- 
tains half  as  much  strychnine. 

Dose:  1  or  2  tablets  at  bedtime,  followed  next  morning  by  1 
tablet  every  three  or  four  hours  until  effective. 

Tablets   Aloin,   Belladonna  and   Strychnine   with   Cas= 
cara,  Squibb 

Per  1000       Per  500       Per  100 
C.  T. 

Chocolate-coated  (C.  C.  T.) 

Aloin  !/5  gr.  1  This  formula  is  a  modinca- 

Extract  Belladonna  i/lG  gr-  I  llon  of  ou«"  Aloin  and  Bella- 
Strychnine  Sulphate  i/eo  gr-  f  donna  Compound.  The 
Extract  Cascara  1/2  gr.  J  change  consists  in  a  reduction 

of  the  quantity  of  extract  of 

belladonna  and  the  addition  of  extract  of  cascara  sagrada, 
a  tonic  laxative,  the  use  of  which  is  said  not  to  cause  habituation, 
but  rather  to  tend  to  restore  the  normal  functions.  Dose:  1  or  2 

tablets,     at     night,     with     water,     repeated     next     morning     if 

required. 

Tablets  Aloin  and  Cascarin  Compound,  Squibb 

(Dr.  Duncan) 

Per  1000       Per  500       Per  100 
C.  T. 
Chocolate=coated  (C.  C.  T.) 

Aloin  !/s  gr.  1       This    Laxative    tablet    is    very 

Cascarin  1/4  gr.  I       popular    with    physicians    for 

Extract  Belladonna        1/g  gr.  f      use    in    indigestion    with    slug- 
Strychnine  Sulphate     I/go  gr«  J      g'sh    liver    and    habitual    con- 
stipation.      It    acts    pleasantly 

without  griping,  and  its  continued  administration  is  not  known 
to  debilitate  the  bowel.  It  has  proved  very  useful  as  a  laxative 
in  atonic  conditions  of  the  intestines.  Dose :  I  or  2  tablets,  at 
bedtime,  with  water,  repeated  the  following  morning  if 
necessary. 


The  Squibb  products  are  recognized  everywhere  as  the  Quality 
Standard.  They  are  of  uniform  purity  and  strength,  hence 
theraupeutically  dependable.  When  ordering  or  prescribing  medi- 
cinal products,  you  will  do  well  always  to  specify  SQUIBB'S. 


314        SQUIBB'S  MATERIA  MEDICA 

Tablets  Aloin  and  Podophyllin  Compound,  Squibb 

(Cathartic)  Per    1000         Per  500         Per   100 

Chocolate-coated  (C.  C.  T.) 

These  tablets  are  an  active 
Cathartic,  used  in  conditions 
where  prompt  and  thorough 
action  of  the  bowels  is  de- 
sired. They  should  not  be 
used,  however,  where  inflam- 
mation of  the  intestines  is 


Aloin  I/ 


,'10  gr- 


Podophyllin  l/io  gr. 

Ext.  Colocynth  Comp.  l/io  gr 
Ext.  Nux  Vomica  l/io  gr- 
Croton  Oil  1/30  gr. 

Oleoresin  Capsicum  1/256  gr- 
Oil  Peppermint  1/i28  min. 


present,  as  they  are  liable  to 
increase  the  irritation.  Dose :  1  tablet  every  two  hours  until 
bowels  move;  or  1  to  3  at  bedtime. 


*  Tablets  Aloin  and  Strychnine  Compound,  Squibb 

Per  1000       Per  500       Per  100 
T.  T. 
Chocolate-coated  (C.  C.  T.) 

Aloin  1/5  gr.  1       In     congested     states     of     the 

Strychnine  Sulphate  I/GO  gr-  I  system  due  to  failure  of  the 
Extract  Belladonna  1/g  gr.  f  bowels  to  perform  their  nat- 
Ipecac  1/16  gr-  j  ural  functions  this  formula  is 

used   with    good    effect.      It    is 

said  to  act  upon  the  entire  alimentary  tract;  for  while  aloin 
alone  affects  the  lower  bowel  almost  entirely,  the  added  bella- 
donna, strychnine  and  ipecac  stimulate  the  peristaltic  action  and 
overcome  the  atonic  condition  of  the  intestinal  tract  and  cause 
a  more  thorough  evacuation  of  its  contents.  Tablets  Aloin  and 
Strychnine  Compound  Squibb  are  used  in  indigestion  with 
hepatic  congestion  and  constipation.  Dose :  1  or  2  tablets,  at 
bedtime,  followed  by  1  after  breakfast  and  dinner  the  following 
day  if  required. 


Tablets  Aloin  and  Strychnine  Compound  No.  2,  Squibb 

Per  1000        Per  500        Per  100 
C.  T. 
Chocolate-coated  (C.  C.  T.) 

Aloin  1/5  gr.  ]       This    formula    is    a    modifica- 

Strychnine  Sulphate  !/(;o  gr.  1  lion  of  the  previous  one,  the 
Extract  Belladonna  Vin  gr.  f  quantity  of  extract  belladonna 
Ipecac  1/16  gr-  J  being  reduced  one-half.  It 

is  intended  specially  for  those 

patients  in  whom  an  idiosyncrasy  for  this  drug  exists.  Dose : 
I  or  2  tablets,  at  bedtime,  followed  by  1  after  breakfast  if 
required. 


SQUIBB'S  MATERIA  MEDICA        315 

Tablets  Aloin  and  Strychnine  Compound  No.  3,  Squibb 
(Laxative  No.  5,  Dr.  W.  B.   Pierson) 

Per  1000        Per  500        Per  100 

Chocolate-coated  (C.  C.  T.) 

Aloin  1/4  gr.  "1        This    is    a    slight    modification 

Strychnine  Sulphate  Veo  gr-  I  °f  our  Aloin  and  Strychnine 
Extract  Belladonna  Vie  gr.  |  Compound  formula,  adapted 
Ipecac  1/16  gr-  J  *°  those  patients  requiring  a 

larger  dose  of  aloin  and  who 

show  an  undue  susceptibility  to  the  action  of  belladonna.  The 
tablets  are  used  in  cases  of  habitual  constipation  with  hepatic 
torpor,  usually  the  result  of  atony  of  the  digestive  functions. 
They  act  pleasantly  without  griping,  and  their  continued  use 
is  not  known  to  debilitate  the  bowels.  Dose :  1  or  2  tablets  at 
night,  and  I  after  breakfast  next  morning  if  needed. 

Tablets  Aloin  Compound,  Squibb 

Per  1000       Per  500       Per  100 
T.  T. 

Chocolate=coated  (C.  C.  T.) 

Aloin  t  !/8  gr.  {      In   sthenic   patients   where   no 

Podophyllin  Vs  gr-  )       inflammatory  condition   of  the 

bowels    exists,    and    where    a 

decided  stimulation  of  the  liver  is  needed,  these  tablets  have 
been  found  to  act  with  decided  benefit.  Podophyllin  is  both 
cholagogue  and  cathartic,  stimulating  the  flow  of  bile  as  well  as 
producing  free  action  of  the  bowels,  but  apparently  acting 
chiefly  upon  the  small  intestine.  The  action  of  aloin  is  laxative 
or  purgative,  depending  upon  the  dose,  and  seems  to  be  exerted 
mainly  upon  the  large  intestine  and  rectum.  These  drugs  usually 
act  well  together,  but  they  have  a  tendency  at  times  to  cause 
griping.  Dose:  1  to  4  tablets  at  bedtime,  gradually  decreasing 
the  dose  as  the  normal  condition  of  the  bowels  returns. 

Tablets  Aloin  Compound  No.  2,  Squibb 

Per  1000       Per  500       Per  100 
T.  T. 

Chocolate-coated  (C.  C.  T.) 

Aloin  V-i  gr.  1      Dose  t    1    or  2   tablets   at  bed- 

Podophyllin  !/4  gr.  )       time,,    reducing     the     dose    as 

the  condition  improves. 

Tablets  Amenorrhea  (Anemic).         See  Tablets  Manganese 
Compound. 


Since  we  make  only  one  quality  of  each  product,  that  best 
suited  to  the  purposes  intended,  the  specification  Squibb's" 
is  not  open  to  various  interpretations,  but  has  a  plain,  positive 
meaning.  When  ordering  or  prescribing,  specify  SQUIBB'S. 


316       SQUIBB'S  MATERIA  MEDICA 

Tablets  Ammonium  Bromide  5  gr.,  Squibb 

Per  1000  Per  500  Per  100 

C.  T. 

As  is  known,  ammonium  bromide  efficiently  acts  as  a  Sedative 
in  nervous  excitement,  whether  caused  by  irritation  of  the  brain, 
the  sexual  system  or  the  spinal  cord;  it  allays  reflex  irritability. 
It  is  used  in  epilepsy,  mania,  sexual  excitement,  seasickness, 
sleeplessness  from  overwork  or  worry  and  in  various  phases  of 
nervous  exaltation.  It  is  believed  to  be  less  depressing  than  the 
sodium  or  potassium  salt,  yet,  on  account  of  its  pungent  and  dis- 
agreeable taste,  it  is  not  so  frequently  employed.  Long-con- 
tinued use  often  causes  an  acne-like  eruption  and  a  depressed 
mental  condition;  but  these  symptoms  usually  disappear  upon 
withdrawal  of  the  medicine.  Dose :  1  to  3  tablets,  with  water, 
repeated  in  an  hour  or  two  if  required. 

Tablets  Ammonium  Chloride  3  gr.,  Squibb 

Per  1000  Per  500  Per  100 

C.  T. 

Ammonium  chloride  is  a  stimulant  expectorant,  and  is  useful  in 
bronchial  catarrhs  where  the  secretion  is  viscid,  tenacious  and 
difficult  to  dislodge,  and  also  in  intestinal  catarrh,  catarrhal  jaun- 
dice and  in  certain  forms  of  neuralgia.  As  a  bronchial  stimu- 
lant it  is  usually  combined  with  other  remedies,  and  usually 
given  with  some  demulcent,  as  extract  licorice,  which  modifies 
its  unpleasant  taste.  Dose:  as  a  bronchial  stimulant,  1  or  2 
tablets  every  two  or  three  hours,  allowed  to  dissolve  in  the 
mouth  or  taken  with  a  wineglass  of  water  or  milk.  For  intes- 
tinal catarrh  and  neuralgia,  5  tablets  dissolved  in  a  wineglass 
of  water,  every  three  or  four  hours. 

Tablets  Ammonium  Chloride  5  gr.,  Squibb 

Per  1000  Per  500  Per  100 

C.  T. 

Dose:  as  an  expectorant,  1  or  2  tablets  dissolved  on  the  tongue 
every  two  or  three  hours;  as  a  hepatic  stimulant,  2  to  4  tablets 
in  half  a  glass  of  water  every  three  or  four  hours. 

Tablets    Ammonium   Chloride   and    Hyoscyamus    Com- 
pound, Squibb 

Per  1000  Per  500  Per  100 

C.T. 

Ammonium  Chloride  I  gr.  1  This  combination  is  employed 
Extract  Hyoscyamus  !/(>  8r-  f  as  an  Anodyne  Expectorant, 
Tartar  Emetic  */24  gr.  J  in  painful  cough  with  absent 

or    only    scanty    expectoration. 

Dose:  1  tablet  after  each  meal,  or  every  three  or  four  hours 
if  required. 


SQUIBB'S  MATERIA  MEDICA        317 

Tablets  Ammonium  Chloride  and  Licorice,  Squibb 

Per  1000  Per  500  Per  100 

C.  T. 

Ammonium  Chloride  1  gr.  "I  These  tablets  represent  an 
Extract  Licorice  3  3/4  gr.  V  agreeable  and  efficient  remedy 
Oil  Anise  i/20  min-  J  m  bronchial  affections  with 

hoarseness    and    thick,    scanty 

sputum  difficult  of  expectoration.  Dose:  I  or  2  tablets  every 
two  or  three  hours. 

f  Tablets  Ammonium  Chloride  and  Sanguinarine  Com= 
pound,  Squibb 

(Anodyne  Expectorant,  Dr.  Bolton) 

Per  1000  Per  500  Per  100 

T.  T. 


Ammonium  Chloride  1  gr. 
Sanguinarine  Nitrate  VlCO  8r- 
Tartar  Emetic  Vso  gr- 

Morphine  Sulphate       ^-/so  gr. 


In  bronchial  affections  where 
the  sputum  is  thick  and 
scanty  and  expectoration  is 
accomplished  with  difficulty 


and  often  painful,  this  combi- 
nation usually  gives  relief.  Sanguinarine,  although  not  now 
used  as  often  as  formerly,  acts  as  a  powerful  stimulant  to  the 
bronchial  mucous  membrane,  and  where  the  dose  is  not  excessive 
is  not  depressing.  In  combination  with  the  well-known  expec- 
•  torants,  ammonium  chloride  and  tartar  emetic,  it  generally  pro- 
duces a  more  fluid  and  copious  secretion  from  the  bronchi. 
The  action  of  the  morphine  quiets  the  cough,  relieves  pain  and 
soreness  of  the  pectoral  muscles,  and  contributes  a  sudorific 
action  to  the  other  remedies.  Dose :  1  or  2  tablets  every  2  or  3 
hours.  In  the  use  of  these  tablets  the  possibility  of  the  for- 
mation of  the  morphine  habit  should  be  borne  in  mind  and 
guarded"  against. 

Tablets    Ammonium    Chloride    and    Squill    Compound, 
Squibb  (Cough  Persistent,  Dr.   Brewer) 

Per  1000  Per  500  Per  100 

C.  T. 

Ammonium  Chloride  2  gr.  1  These  tablets  are  used  in 
Ext.  Squill  Acetic  1/4  gr.  1  subacute  bronchitis  with  thick, 
Ipecac  */4  gr-  J  viscid  mucus,  difficult  ex- 

Fluidext.   Senega  1  min.  J       pectoration         and        obstinate 

cough,  to  stimulate  the  secre- 
tion of  bronchial  mucus,  and  to  render  it  more  fluid,  less 
tenacious  and  more  easily  expectorated.  Owing  to  the  nause- 
ating tendency  of  the  squill  and  ipecac,  they  are  not  adapted 
for  patients  with  sensitive  stomachs.  Dose:  1  tablet  every  two 
or  three  hours. 


The  founder  of  the  House  of  Squibb,  Dr.  Edward  R.  Squibb, 
not  only  had  high  ideals,  but  lived  and  labored  for  them;  and, 
in  the  words  of  William  Miller  Bartlett,  "the  House  of  Squibb 
stands  today  as  a  living  monument  to  the  honor,  integrity,  zeal 
and  devotion  of  its  founder." 


318       SQUIBB'S  MATERIA  MEDICA 

f  Tablets  Ammonium  Chloride  and  Squill  Compound, 
with  Heroin,  Squibb 

(Cough  Persistent,  with  Heroin) 
C.  T.  Per  1000  Per  500  Per  100 


Ammonium  Chloride  2  gr. 

Ext.  Squill  Acetic  1/4  gr. 
Diacetylmorphine 

(Heroin)  1/25  gr. 

Ipecac  1/4  gr. 

Fluidext.  Senega  1  min. 


These  tablets  act  as  a  stim- 
ulant Expectorant  and  An- 
odyne, and  are  deemed 
especially  useful  in  subacute 
and  chronic  bronchitis  when 
the  cough  is  obstinate  and 


painful  and  the  expectoration 
scanty.  Nausea  is  apt  to  be  incited  by  these  tablets  at  times. 
Dose :  1  tablet  every  hour  or  two,  depending  upon  the  severity 
of  the  symptoms.  In  the  use  of  these  tablets  the  possibility 
of  the  formation  of  the  morphine  habit  should  be  borne  in 
mind  and  guarded  against.  (NOTE. — We  also  make  this  com- 
bination with  Diacetylmorphine,  the  U.  S.  P.  name  for  heroin, 
and  can  offer  them  at  lower  prices  than  those  charged  for  the 
tablets  containing  the  trademarked  product.) 
Tablets  Ammonium  Chloride  Compound,  Squibb 

T.  T.  Per  1000  Per  500  Per  100 

Ammonium  Chloride      1/4  gr. }       These     tablets     are     generally 

-  Extract  Licorice  !/io  gr.  >      useful    in    the    early    stage    of 

Cubeb  1/8  gr.  J       bronchitis,    acting    as    a    mild 

stimulating    Expectorant. 

Dose:  I  or  2  tablets  dissolved  on  the  tongue  every  fifteen  or 
twenty  minutes  until  relieved. 

f*  Tablets   Ammonium   Chloride   Compound   with   Co= 
deine,  Squibb  Per  1000          Per  500          Per  100 

T.  T. 

Ammonium  Chloride  1/4  gr.  1  This  formula  acts  as  an  Ex- 
Codeine  1/25  gr-  I  pectorant  and  mild  Anodyne. 
Extract  Licorice  l/io  gr.  F  It  has  been  found  useful  in 
Cubeb  1/8  gr.  J  the  early  stage  of  bronchitis, 

with      frequent      and      painful 

cough  and  before  the  secreting  stage  is  well  established.  Dose: 
1  tablet,  dissolved  on  the  tongue,  every  fifteen  minutes  to  half 
hour  until  relieved. 

f*  Tablets      Ammonium      Chloride      Compound      with 
Heroin,  Squibb 

T.  T.  Per  1000  Per  500  Per  100 


Ammonium  Chloride      1/4  gr. 
Diacetylmorphine 

(Heroin)  1/100  gr. 

Extract  Licorice  l/io  gr. 

Cubeb  1/g  gr. 


This  combination  is  employed 
in  the  early  stage  of  coughs 
and  colds,  to  relieve  the  irri- 
tation and  soreness  of  the 


throat,  facilitate  expectoration, 
and    allay    cough.       Dose :     1 

tablet,  dissolved  in  the  mouth  every  fifteen  minutes  to  half  an 
hour  until  4  have  been  taken,  then  every  hour  or  two  until 
relieved.  The  possibility  of  the  formation  of  the  morphine 
habit  should  be  borne  in  mind  when  prescribing  these  tablets, 
and  guarded  against. 


SQUIBB'S  MATERIA  MEDICA        319 

f  Tablets  Ammonium  Chloride  Compound  with  Heroin, 
No.  2,  Squibb  (Cough,  Infants') 

T.  T.  Per  1000  Per  500  Per  100 


Ammonium  Chloride      1/4  gr. 
Diacetylmorphine    (Her- 
oin) Hydrochlor.     1/200  gr- 
Fluidextract  Ipecac      1/s  min. 
Tr.  Belladonna  1/5  min. 

Licorice 
Oil  Anise  aa.  q.  s. 


The  addition  of  ammonium 
chloride  and  ipecac  serves  to 
produce  an  increased  secre- 
tion from  the  bronchial 
mucous  membrane.  Bella- 
donna, in  addition  to  its  anti- 
spasmodic  effect,  acts  as  a 
respiratory  stimulant.  The  oil 
anise  and  licorice  make  the  tablets  palatable,  and  hence  they 
are  readily  taken  by  children.  Dose :  for  young  children,  a 
tablet  may  be  dissolved  in  water  before  administering  and  given 
at  hourly  intervals  until  relieved;  older  children  take  1  or 
more  tablets  at  a  dose.  The  bottle  should  be  kept  well  corked 
and  in  a  dry  place.  The  possibility  of  the  formation  of  the 
morphine  habit  should  be  borne  in  mind,  when  prescribing 
these  tablets,  and  guarded  against. 

f  Tablets  Ammonium  Salicylate  and   Acetanilid  Com- 
pound, Squibb  Per  1000  Per  500          Per  100 
C.  T. 


Ammonium  Salicylate 

Acetanilid 

Dover's  Powder 

Camphor 

Caffeine 


2  gr.  This  formula  is  used  in  the 
early  stages  of  coryza  and 
grip.  It  usually  acts  promptly, 
allaying  pain,  controlling  the 
febrile  symptoms,  and,  if 
taken  early  enough,  frequently 
1  or  2  tablets  every  two  or  three 


Dose: 


aborting  an   attack, 
hours,  with  water. 

Tablets  Analgesic.         See    Tablets   Acetanilid    and   Strontium 
Salicylate  Compound. 

Tablets  Analgesic  No.  2.     See  Tablets  Acetanilid  and  Sodium 
Salicylate  Compound. 

Tablets  Analgesic  Compound.      See  Tablets  Acetanilid  and 
Morphine  Compound. 

Tablets  Anemia.     See  Tablets  Blaud's  and  Manganese  Comp. 

Tablets  Anodyne.    See      Tablets      Morphine,      Camphor     and 
Hyoscyamus. 

Tablets  Anodyne  Expectorant    (Dr.  Bolton). 

See  Tablets  Ammonium  Chloride  and  Sangumanne  Compound. 

Tablets  Anodyne,  Infants'    (Dr.  Waugh). 
See  Tablets  Codeine  and   Nickel  Compound. 


The  Squibb  Ideals  have  taken  concrete  form  in  the  Squibb 
Products;  these  are  universally  recognized  as  standards  of 
uniform  Purity  and  Efficacy,  that  is,  genera)  Excellence  and 
Reliability.  Specify  SQUIBB'S  when  prescribing  or  ordering. 


320       SQUIBB'S  MATERIA  MEDICA 

Tablets  Anorexia.       See  Tablets  Gentian  and  Nux  Compound. 

Tablets  Anorexia  No.  2    (Dyspeptic).      See    Tablets    Strych- 
nine and  Ipecac  Compound. 

Tablets  Antiasthmatic.       See   Tablets    Potassium   Iodide   and 
Belladonna  Compound. 

Tablets  Antiasthmatic  No.  2.    See  Tablets  Potassium  Iodide 
and    Lobelia   Compound. 

Tablets  Anticonstipation.      See  Tablets  Cascara  Comp.  No.  4. 

Tablets  Antidyspeptic.     See    Tablets    Rhubarb    and    Sodium 
Bicarbonate  Compound. 

Tablets  Antifermentative.  See  Tablets  Sodium  Salicyl.  Comp. 
Tablets  Antihydrotic.         See  Tablets  Agaricin  Compound. 

Tablets  Antimony  and  Ipecac,  Squibb     (Dr.  Fowler) 

T.  T.  Per  1000  Per  500  Per  100 

Tartar  Emetic  Vioo  §«"•  j      Tartar    emetic    in    small    and 

Ipecac  VlOO  8r-  j       repeated     doses     acts     as     an 

Expectorant  and  Diaphoretic ; 

in  larger  quantities  it  causes  nausea,  vomiting  and  great  prostra- 
tion. It  is  deemed  useful  in  the  early  stage  of  bronchitis  before 
the  secretion  is  well  established.  In  combination  with  ipecac  it 
is  regarded  as  an  excellent  remedy  in  acute  affections  of  the 
bronchi  with  hard,  painful  cough,  deficient  secretion  and  fever. 
Dose :  1  tablet  every  hour  or  two,  stopping  the  remedy  on  the 
appearance  of  nausea. 

Tablets  Antimony  and  Ipecac  No.  2,  Squibb 

C.  T.  Per  1000  Per  500  Per  100 

Tartar   Emetic  VlOO  gr-  )      This  formula  is  a  modification 

Ipecac  1/4  gr.  J       of     the     prescription     of     Dr. 

Fowler;    it    contains    a    larger 

proportion  of  ipecac,  which  increases  the  expectorant  action 
without  producing  subsequent  depression.  It  is  indicated  in 
bronchial  congestion  with  fever,  where  the  cough  is  hard  and 
painful  and  the  secretion  scanty.  Dose :  1  tablet  every  hour 
or  two  as  required. 

Tablets  Antipyrine  1  gr.,  Squibb 

T.  T.  Per  1000  Per  500  Per  100 

Pains  of  a  reflex  or  spasmodic  character  as  seen  in  locomotor 
ataxia,  migraine,  and  neuralgia  are  commonly  relieved  by  anti- 
pyrine.  Good  results  have  also  been  obtained  in  asthma  and  in 
whooping-cough.  Its  antipyretic  properties  are  well  known,  but 
it  should  be  cautiously  used.  (See  note  under  Tablets  Acetani- 
lid  1  gr.)  Dose:  for  children,  1  tablet  every  hour  until  tem- 
perature falls,  or  pain  is  relieved;  for  whooping-cough  I  tablet 
every  two  hours. 


XSQUIBB'S  MATERIA  MEDICA        321 

Tablets  Antipyrine  5  gr.,  Squibb 

Per  1000  Per  500  Per  100 

C.  T. 

Dose:  as  an  Antipyretic,  1  tablet  every  two  or  three  hours 
while  fever  is  high;  as  an  Analgesic,  I  every  hour  for  three 
doses,  or  3  at  one  dose,  depending  upon  the  condition. 

f  Tablets  Antipyrine  and  Heroin  Compound,  Squibb 

(Whooping-Cough) 

Per  1000  Per  500  Per  100 

T.  T. 


Antipyrine  1/2  gr. 

Diacerylmorphine    (Her- 
oin) Hydrochlor.     */200  gr. 
Tincture  Drosera  1  min. 

Tr.  Bell.  US.P.  "90  1/5  min. 
Ipecac  ^/200  gr« 

Oil  Anise  q.  s. 


Antipyrine  is  quite  generally 
conceded  to  be  a  useful  rem- 
edy in  whooping-cough.  It 
is  combined  in  this  formula 
with  respiratory  stimulants 
and  antispasmodics,  which 


increase    its    efficiency.       The 
combination    is   palatable    and 

readily  taken  by  children.     Dose:   1    tablet  every  hour  or  two 

until  relieved,  and  then  at  longer  intervals. 

Tablets  Antirheumatic.     See    Tablets    Potassium    Iodide   and 
Phytolacca   Compound. 

Tablets  Antirheumatic  No.  2.     See   Tablets   Acid   Salicylic 
and  Colchicum  Compound. 

Tablets   Antirheumatic   No.   3.     See  Tablets  Sodium  Salicy- 
late and  Colchicum  Compound  No.  2. 

Tablets  Antiseptic,  Bernays'.      See    Tablets    Mercury    Bi- 
chloride Compound,   Bernays'. 

Tablets   Antiseptic,   Detergent.      See     Tablets     Borax     and 
Sodium  Salicylate  Compound. 

Tablets  Antiseptic,  Detergent,  Improved.        See    Tablets 
Borax  and  Sodium  Salicylate  Compound,   Improved. 

Tablets  Antiseptic  Intestinal.        See  Tablets  Zinc  Sulpho- 
carbolate  Compound. 

Tablets   Antiseptic,    Wilson's.      See     Tablets     Mercury     Bi- 
chloride Compound,   Wilson's. 

Tablets  Aphrodisiac.     See  Tablets  Nux  and  Phosphorus  Comp. 

The  Squibb  Label  on  a  package  is  a  positive  guaranty  for  the 
uniform  Purity  and  Reliability  of  the  product.  We  make  only 
ONE  quality:  the  SQUIBB  quality;  and  our  prices  are  as  low 
as  they  can  be  made  for  that  quality.  Specify  SQUIBB'S. 


322       SQUIBB'S  MATERIA  MEDICA 

f  Tablets  Apomorphine  Hydrochloride  1/100  gr.,  Squibb 

Per  1000  Per  500  Per  100 

C.  T. 

Apomorphine  hydrochloride,  according  to  physiologists,  at  first 
stimulates  the  respiratory  centers,  and  if  the  dose  be  sufficient  to 
nauseate,  causes  marked  depression;  small  doses  given  by  the 
mouth  act  as  an  Expectorant  and  are  useful  in  early  stages  of 
inflammation  of  the  bronchi,  where  a  hyperemic  condition  of  the 
mucous  membrane  exists,  and  the  secretion  is  viscid  and  difficult 
to  expectorate.  In  larger  doses  it  is  an  active  Emetic,  but  must 
be  given  with  caution,  as  it  occasions  marked  depression.  As  an 
emetic  it  is  used  principally  in  case  of  poisoning  and  where  a 
prompt  and  certain  effect  is  wanted.  For  this  purpose  it  is  gen- 
erally given  hypodermically.  Dose :  1  tablet  every  three  or 
four  hours. 

f  Tablets  Apomorphine  Hydrochloride  1/20  gr.,  Squibb 
Per  1000  Per  500  Per  100 

C.  T. 

Dose:  1  tablet  as  an  emetic,  repeated  cautiously  until  effective. 

f  Tablets  Apomorphine  Hydrochloride  1/10  gr.,  Squibb 

Per  1000  Per  500  Per  100 

C.  T. 

Dose :  1  tablet  as  an  emetic  in  case  of  poisoning  or  choking 
due  to  presence  of  foreign  body  in  the  esophagus. 

Tablets  Arsenates  Triple.  See  Tablets  Triple  Arsenates. 
Tablets  Arsenic  and  Iron.     See  Tablets  Iron  and  Arsenic. 

Tablets  Arsenic  Iodide  1/50  gr.,  Squibb 

Per  1000  Per  500  Per  100 

C.  T. 

This  remedy  is  employed  in  cutaneous  eruptions  of  a  chronic 
character  and  some  forms  of  malarial  poisoning.  Small  doses 
are  commenced  with,  and  if  gastric  distress  or  reddening  of  the 
eyelids  occur,  the  drug  is  withheld  until  the  symptoms  disappear 
and  then  resumed.  Good  effects  have  been  observed  in  psoriasis, 
chronic  eczema  and  other  obstinate  skin  diseases.  Dose:  1  or 
2  tablets  after  eating.  Dispense  in  glass. 

Tablets  Arsenic  Iodide  1/25  gr.,  Squibb 

Per  1000  Per  500  Per  100 

C.  T. 

Dose :  1  tablet  with  water  after  each  meal.  To  be  discontinued 
if  pain  or  fulness  of  the  stomach  occur.  Dispense  in  glass. 


SQUIBB'S  MATERIA  MEDICA        323 

*  Tablets  Arsenic  Sulphide  Red  1/50  gr.,  Squibb 

T.  T.  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 

Arsenic  Sulphide  Red  is  used  in  acne,  eczema,  psoriasis,  and  in 
suppurative  skin  diseases.  The  effect  of  arsenic  is  observed  in 
nutrition,  the  p'atient  gaining  in  weight  and  the  skin  becoming 
soft  and  smooth.  In  combination  with  sulphur  it  is  reported 
especially  useful  in  suppurative  skin  diseases  and  excellent  re- 
sults have  been  obtained  in  the  treatment  of  boils  and  carbuncles. 
As  with  all  arsenical  preparations,  its  effect  upon  the  system 
must  be  watched.  The  dose  is  generally  increased  to  the  point 
of  toleration,  when,  if  gastric  symptoms  or  reddening  of  the 
eyelids  occur,  it  is  lessened  or  the  remedy  withdrawn  for  a  short 
time  and  then  resumed.  Dose:  1  tablet,  gradually  increased  to 
3  or  4,  after  meals. 

*  Tablets  Arsenic  Sulphide  Red  1/30  gr.,  Squibb 

T.  T.  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 
Dose :     1    tablet  after  meals,  gradually  increased. 

Tablets  Arsenous  Acid.      See  Tablets  Acid  Arsenous. 

Tablets  Asafetida  2  gr.,  Squibb 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 
Dose:  1  or  2  tablets  after  meals  and  at  bedtime. 

Tablets  Asafetida  3  gr.,  Squibb 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 
Dose:    1    or  2   tablets  after   meals   and   at  bedtime. 

Tablets  Asafetida  5  gr.,  Squibb 

Per  1 000         Per  500         Per  100 
Chocolate-coated  (C.  C.  T.) 

These  tablets  act  as  an  Antispasmodic  and  Nerve  Sedative,  and 
have  been  found  useful  in  hysteria,  hypochondriasis  and  other 
functional  nervous  disorders,  as  well  as  in  flatulent  dyspepsia. 
Dose :  1  or  2  tablets  after  meals  and  at  bedtime. 

Tablets  Asafetida  and  Nux  Vomica,  Squibb 

Chocolate-coated  (C.  C.  T.)  Per  1000  Per  500  Per  100 
Asafetida  Powdered  3  gr.  \  The  addition  of  nux  vomica 
Extract  Nux  Vomica  */4  gr.  j  to  asafetida  increases  its  value 

in    atonic    conditions    of     the 

alimentary  tract.  The  combination  has  been  found  useful  in 
hysterical  and  neurasthenic  subjects  who  suffer  much  abdominal 
distress  after  meals,  due  to  flatulence  and  fermentation.  Dose : 
1  or  2  tablets  after  meals  and  at  bedtime. 


Squibb's  Tablets  are  made  from  the  Squibb  quality  of  ingredients 
and  by  improved  processes  that  insure  accurate  dosage  and 
rapid  and  complete  disintegration  or  solution  in  the  system, 
hence  prompt  and  full  therapeutic  effect.  Specify  SQUIBB'S. 


324        SQUIBB'S  MATERIA  MEDICA 

Tablets  Asafetida  and  Valerian  Compound,  Squibb 

(Sedative  No.  3,  Dr.  Baer) 

Per  1000     Per  500     Per  100 
Chocolate-coated  (C.  C.  T.) 

Asafetida  Powdered  1  gr.  "1  These  tablets  are  used  as  an 
Extract  Valerian  1  gr.  j-  antispasmodic  and  sedative  in 

Extract  Sumbul  1  gr.  J      mild    cases    of   nerve    disorder 

accompanied       by      flatulence 

and  intestinal  disturbance.  They  are  well  adapted  for  relieving 
the  nervous  manifestations  seen  in  hysteria  and  melancholia 
occurring  specially  in  women.  Of  late  years  it  has  grown 
more  and  more  difficult  to  secure  asafetida  of  the  proper  stand- 
ard, and  many  samples  have  been  condemned  by  our  control 
laboratory.  The  asafetida  used  in  these  tablets  is  of  the  highest 
quality,  and  great  care  is  exercised  so  that  its  properties  are  not 
impaired  during  the  process  of  their  manufacture.  Dose:  1  tab- 
let after  meals  and  at  bedtime. 

Tablets  Aspirin.        See  Tablets  Acid  Acetylsalicylic. 

Tablets,   Astringent  Gargle.     See     Tablets     Hydrastis     and 
Alum  Compound. 

Tablets  Astringent,  Vaginal.    See    Tablets    Zinc    Sulphate 
and  Tannic  Acid  Compound. 

Tablets,  Astringent  Wash.    See    Tablets    Lead    and    Zinc 
Compound. 

Tablets  Atropine  Sulphate  1/200  gr.,  Squibb 

T.  T.  Per  1000  Per  500  Per  100 

Dose :  1  tablet  every  hour  until  throat  feels  dry,  but  not  for 
more  than  four  consecutive  doses. 

Tablets  Atropine  Sulphate  1/150  gr.,  Squibb 

T.  T.  Per  1000         Per  500         Per  100 

Dose:  1  tablet  every  hour  until  dryness  of  throat  occurs,  but 
not  for  more  than  four  doses  in  succession. 

*  Tablets  Atropine  Sulphate  1/100  gr.,  Squibb 

T.  T.  Per  1000  Per  500  Per  100 

Atropine  is  used  as  a  cardiac  and  respiratory  stimulant  and  for 
its  effect  upon  the  glands.  It  arrests  and  even  suppresses  the 
action  of  the  mammary,  sudoriparous  and  salivary  glands.  Ad- 
vantage of  its  action  in  controlling  sweating  has  been  taken  in 
the  treatment  of  night-sweats  in  phthisis,  and  of  its  effect  of 
reducing  the  secretions  of  the  mucous  membrane  in  acute  coryza. 
In  addition,  it  possesses  antispasmodic  properties,  which  are 
shown  in  the  relief  afforded  in  spasm  of  the  sphincter  of  the 
bladder,  neuralgia,  asthma  and  whooping-cough.  Dose :  1  tablet 
every  hour  until  throat  becomes  dry,  but  for  not  more  than  three 
doses. 


SQUIBB'S  MATERIA  MEDICA        325 

Tablets  Atropine  and  Morphine.       See    Tablets    Morphine 
and  Atropine. 

Tablets  Belladona  and  Aconite.     See  Tablets  Aconite  and 
Belladonna. 

Tablets  Belladonna  and  Aconite  Compound.     See  Tablets 
Aconite  and  Belladonna  Compound. 

Tablets  Belladonna,  Nux  and  Cubeb,  Squibb 

(Incontinence) 

C.  T.  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 


Tr.  Bell.  U.S.P.  '90  2  min. 

Tr.  Nux  Vom.  "  1  min. 

Tr.  Cubeb  2  min. 

Tr.  Rhus  Aromat.  1  min. 

Tr.  Cascarilla  2  min. 


Incontinence  of  urine  in  chil- 
dren is  often  corrected  by 
the  administration  of  these 
tablets,  especially  when  due 
to  irritable  bladder.  To 


overcome  the  acidity  and 
concentration  which  are  often  the  exciting  causes,  considerable 
water  should  be  taken  during  the  day,  but  the  quantity  should 
be  restricted  towards  evening.  Dose:  1  or  2  tablets  at  night, 
for  a  child  six  to  eight  years. 

Tablets  Betanaphthol  Compound,  Squibb 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 

Betanaphthol  1  gr.  1       Betanaphthol     is     a     reliable 

Bismuth  Salicylate  1  gr.  ?•      remedy    in    morbid    conditions 

Aromatic  Chalk  Powd.     1  gr.  J       of    the     alimentary     tract,     as 

seen  in  diarrhea  and  dysen- 
tery, as  well  as  in  dilated  stomach,  where  the  contents  of  that 
organ  are  not  completely  emptied,  and  fermentation  is  a  prom- 
inent symptom.  Bismuth  salicylate  (subsalicylate)  acts  as  a 
sedative  and  astringent  to  the  mucous  membranes;  aromatic 
chalk  powder  as  a  carminative  and  antacid.  Dose :  1  tablet, 
with  a  glass  of  water,  half  an  hour  before  meals,  repeated  in 
two  hours  if  required;  for  diarrhea  1  tablet  every  two  or  three 
hours  until  relieved. 

Tablets  Bismuth  and  Cascara,  Squibb 

(Dyspeptic  No.  2)     Per   1000         Per  500         Per   100 

C.  T. 

Bismuth  Subgallate  5  gr.  }      The    tonic    laxative    effects    of 

Extract  Cascara  1  gr.  j      cascara     are     here     combined 

with  bismuth  subgallate.     The 

latter  is  considered  an  excellent  remedy  in  flatulent  dyspepsia, 
but  at  times  it  causes  constipation.  The  cascara  overcomes  this 
objection  and  together  they  generally  give  marked  relief.  Dose: 
1  tablet  after  meals,  with  water. 

This  house  supplies  only  one  quality  of  each  product:  that  best 
suited  to  the  purposes  intended.  The  specification  "Squibb's" 
is  not  open  to  various  interpretations;  it  has  a  plain,  posi- 
tive meaning.  When  prescribing,  please  specify  SQUIBB'S. 


326        SQUIBB'S  MATERIA  MEDICA 

f   Tablets   Bismuth   and   Cerium    Oxalate     Compound, 
Squibb  (Nausea  No.  2) 

Per  1000          Per  500  Per  100 

C.  T. 

Bismuth  Subnitrate  2  gr.  1       These  tablets  are  used  for  the 

Cerium  Oxalate  2  gr.  V      relief  of  vomiting  in  pregnacy. 

Cocaine  Hydrochlor.  1/12  gr.  J      car    sickness,    seasickness,    and 

nausea.      On    account    of    the 

contained  cocaine  they  should  be  given  with  caution  lest  a 
habit  be  formed.  Where  the  nausea  is  excessive  and  much 
liquid  cannot  be  given,  the  tablet  may  be  placed  in  a  spoon 
with  a  few  drops  of  water,  when  it  will  disintegrate  at  once. 
Dose :  1  tablet  in  a  teaspoonful  of  water  every  hour. 


Tablets  Bismuth  and  Magnesia  No.  1,  Squibb 

Per  1000  Per  500  Per  100 

C.  T. 

Bismuth  Subnitrate  15  gr.  7  This  formula  affords  a  corn- 
Magnesia  Calcined  lOgr.  }  bination  having  the  properties 

of     an     Antacid,     Stomachic, 

Gastro-intestinal  Astringent  and  Antizymotic.  It  is  a  favorite 
with  many  surgeons  as  a  means  of  preventing  as  well  as  com- 
bating the  formation  of  flatus  after  operations.  Dose :  1  tablet 
aboift  two  hours  after  meals,  or  every  three  or  four  hours. 

Tablets  Bismuth  and  Magnesia  No.  2,  Squibb 

Per  1 000  Per  500  Per  100 

C.  T. 

Bismuth  Subnitrate  15gr,  1  Action  and  uses  essentially 
Magnesia  Calcined  5  gr.  )  same  as  preceding;  more 

Astringent    and    less    Antacid. 

Dose :  1  tablet  about  two  hours  after  meals,  or  every  three  or 
four  hours  if  required. 

Tablets  Bismuth  and  Magnesia  No.  3,  Squibb 

Per  1000  Per  500  Per  100 

C.  T. 

Bismuth  Subnitrate  lOgr.  |  Dose:  1  tablet  about  two 
Magnesia  Calcined  lOgr.  }  hours  after  meals,  or  every 

three  or  four  hours  if  required. 

Tablets  Bismuth  and  Sodium  Bicarbonate,  Squibb 

Per  1000  Per  500  Per  100 

C.  T. 

Bismuth  Subnitrate  lOgr.  )       This  combination  is  prescribed 

Sodium  Bicarbonate         10  gr.)       as    an    Antacid,    Antizymotic 

and  Gastrointestinal  Astrin- 
gent, in  acid  dyspepsia,  flatulence  and  diarrhea.  Dose !  1  tablet 
about  two  hours  after  meals,  or  every  three  or  four  hours  if 
required. 


SQUIBB'S  MATERIA  MEDICA       327 

Tabfets  Bismuth  Compound.  Squibb 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 


Bismuth  Subcarb.  1  */5  8r- 

Betanaphthol  3/io  gr. 

Salol  !/2  gr. 

Creosote  i/2  gr. 

Oil  Cloves  q.  a. 


Astringent,  Antizymotic,  Pro- 
phylactic.     Morbid   conditions 


of  the  alimentary  tract  due 
to  fermentative  decomposition 
or  to  septic  infection  are  indi- 
cations for  the  use  of  these 
tablets.  They  combine  a  number  of  well-known  antiseptics, 
which,  by  preventing  putrefactive  changes,  allow  digestion  to 
proceed  in  a  normal  manner.  Dose :  1  or  2  before  or  after 
meals,  repeated  in  two  hours  if  required.  For  diarrhea  and 
in  typhoid,  1  every  two  or  three  hours. 

Tablets  Bismuth  Compound  No.  2,  Squibb 

Per  1000  Per  500  Per  100 

T.  T. 

Bismuth  Subnitrate  1/2  gr-  \  This  is  a  mild  sedative  to 
Cerium  Oxalate  1/2  gr> }  mucous  surfaces,  used  in 

simple    nausea,    and    in    some 

cases  of  infantile  diarrhea  with  nausea  as  a  disturbing  symptom. 
These  tablets  are  so  made  that  they  disintegrate  at  once  in  water. 
Where  a  child  or- older  person  cannot  swallow  a  tablet,  or  where 
nausea  exists,  one  or  more  may  be  placed  in  a  spoonful  of  water, 
when  they  will  instantly  crumble  to  powder.  Dose :  1  or  2 
tablets  repeated  hourly  until  nausea  is  relieved. 

Tablets  Bismuth  Oxide  Hydrated  5  gr.,  Squibb 

Per  1000     Per  500     Per  100 

C.  T. 

This  addition  to  our  list  has  been  made  at  the  request  of  many 
physicians  who  desired  a  tablet  for  the  extemporaneous  prep- 
aration of  Milk  of  Bismuth  (Magma  Bismuthi).  The  tablets 
disintegrate  at  once  in  water,  and  eight  tablets  added  to  an  ounce 
of  water  and  shaken  slightly  form  a  milky  mixture  from  which 
the  bismuth  oxide  separates  on  standing,  but  quickly  mixes  again 
to  a  perfectly  homogeneous  liquid  upon  slight  agitation.  The 
bismuth  oxide  seems  to  possess  the  power  of  coating  a  much 
larger  surface  than  the  subnitrate  or  subcarbonate.  The  indi- 
cations for  its  use  are  the  same  as  those  for  the  subnitrate  or 
subcarbonate.  Dose :  1  to  3  tablets  repeated  every  half  hour 
until  relieved,  swallowed  with  a  little  water  or  diffused  in  a 
spoonful  of  water  before  taking. 


The  prices  of  the  Squibb  Products  are  in  all  instances  as  low  as 
the  quality  and  quantity  of  ingredients  and  the  expense  of  man- 
ufacture allow.  They  include  containers,  packing  and  boxing.  When 
ordering  or  prescribing  medicinal  products,  specify  SQUIBB'S. 


328        SQUIBB'S  MATERIA  MEDICA 

Tablets  Bismuth  Salicylate  1  gr.,  Squibb 

Per  1000  Per  500  Per  100 

C.  T. 

Bismuth  salicylate  (subsalicylate)  acts  as  an  Astringent  and 
Sedative  to  the  mucous  membranes  and  possesses  Antiseptic 
properties.  It  is  found  useful  in  all  catarrhal  conditions  of  the 
alimentary  canal,  checking  fermentation,  allaying  inflammation 
and  acting  as  a  tonic  and  astringent.  In  diarrhea,  dysentery  and 
typhoid  its  use  has  been  followed  with  good  results.  Dose: 
1  -  tablet  every  hour  until  symptoms  improve. 

Tablets  Bismuth  Salicylate  5  gr.,  Squibb 

Per  1000  Per  500  Per  100 

C.  T. 

Dose :  1  tablet  with  water  every  two  or  three  hours  until  re- 
lieved. In  fermentative  dyspepsia,  1  tablet  half  an  hour  before 
meals  and  1  tablet  two  hours  afterwards. 

Tablets  Bismuth  Subcarbonate  5  gr.,  Squibb 

Per  1000  Per  500  Per  100 

C.  T. 

Bismuth  subcarbonate  is  preferred  by  som«  practitioners  to  the 
subnitrate.  It  acts  as  an  Antacid  and  Astringent,  and  is  con- 
sidered valuable  in  flatulent  dyspepsia,  diarrhea,  pyrosis,  nausea, 
vomiting  and  gastric  pain  and  inflammation.  Dose:  1  or  2 
tablets,  repeated  every  half  hour  or  two  until  relieved,  in  nausea, 
flatulent  dyspepsia,  pyrosis  and  diarrhea. 

Tablets  Bismuth  Subgallate  1  gr.,  Squibb 

P«r1000  Per  500  Per  100 

T.  T. 

Bismuth  subgallate  has  been  highly  recommended  in  fermenta- 
tive dyspepsia.  In  addition  to  the  Sedative  and  Antiseptic 
properties  of  bismuth,  it  has  Astringent  action  owing  to  the  pres- 
ence of  the  gallic  acid.  It  has  been  used  with  advantage  in  the 
treatment  of  fermentative  disorders  of  the  stomach  and  bowels, 
accompanied  with  nausea,  flatulence,  pyrosis  and  diarrhea;  in 
acute  and  chronic  catarrhal  conditions  of  the  alimentary  tract. 
Dose :  for  children,  1  tablet  every  hour  or  two,  to  control 
vomiting  and  diarrhea. 

Tablets  Bismuth  Subgallate  3  gr.,  Squibb 

Per  1000  Per  500  Per  100 

C.T. 

Dose:  for  diarrhea,  1  or  2  tablets  every  two  or  three  hours 
until  relieved.  As  a  gastric  sedative,  1  or  2  tablets  before 
meals,  repeated  in  an  hour  or  two  if  required. 


SQUIBB'S  MATERIA  MEDICA        329 

Tablets  Bismuth  Subgallate  5  gr.,  Squibb 

C.T.  Per  1000  Per  500  Per  100 

Dose :  for  gastric  dyspepsia  1  tablet  before  meals,  repeated 
in  two  hours  if  necessary;  for  diarrhea,  1  to  3  tablets  every  two 
or  three  hours  until  relieved,  preferably  in  combination  with 
betanaphthol  or  zinc  sulphocarbolate.  (See  Tablets  Zinc  Sul- 
phocarbolate  Compound.) 

Tablets  Bismuth  Subgallate  Compound,  Squibb 

(Dr.  Aulde) 

C.T.  Per  1000  Per  500  Per  100 

Bismuth  Subgallate  5  gr.  "1       In  slow  and  imperfect  gastric 

Pepsin  1  gr.  ?•      digestion    of    food    due    to    an 

Extract  Nux  Vomica      */4  gr.  J       atonic    condition    of    the    sto- 
mach,  these  tablets  have  been 

found  to  give  marked  relief.  Bismuth  subgallate  acts  as  a  tonic 
and  astringent  to  the  mucous  membrane;  pepsin  supplies  the 
gastric  ferment  where  that  agent  is  deficient  in  quantity  or  weak 
in  digestive  power;  nux  vomica  acts  as  a  stimulant  to  the 
peptic  cells  of  the  stomach,  and  is  considered  one  of  the  best 
remedies  in  enfeebled  states  of  that  organ,  enabling  the  stomach 
to  tolerate  and  digest  food  and  affording  relief  in  the  various 
distressing  symptoms  arising  from  faulty  digestion.  Dose : 
1  tablet  with  a  swallow  of  water  before  meals,  repeated  after 
meals  if  required. 

Tablets  Bismuth  Subgallate  Compound  No.  2,  Squibb 

(Dr.  Aulde) 

C.T.  Per  1000  Per  500  Per  100 

Bismuth  Subgallate  3*/2  gr.  "|  The  purpose  of  this  formula 
Pancreatin  l^gr-  r  is  to  assist  the  digestion  of 

Extract  Nux  Vomica      */4  §r-  J       starchy       and       fatty       foods. 

The   pancreatin   used    in   these 

tablets  conforms  to  the  U.  S.  P.  requirements  and  is  present  in 
an  active  form.  Fermentative  dyspepsia  with  flatulence  and 
diarrhea  due  to  undigested  food  in  the  intestines,  is  the  indi- 
cation for  these  tablets.  Dose :  1  tablet  before  meals,  repeated 
in  two  hours  if  necessary. 

f  Tablets  Bismuth  Subgallate  Compound  No.  3,  Squibb 

(Diarrhea   Fermentative,   Dr.   J.  W.   Hyde) 
C.T.  Per  1000  Per  500  Per  100 


Bismuth  Subgallate  1  gr. 

Salol  1  gr. 

Cerium  Oxalate  1  gr. 

Dover's  Powder  2  gr. 

Oil  Anise  q.  s. 


This  has  proved  an  excellent 
combination  in  acute  attacks 
of  summer  diarrhea,  with  flat- 
ulence, fermentation,  cramps 


and    frequent   discharges    from 
the    bowels.       It    arrests     fer- 
mentation,   allays    the    irritation    and   pain,    and   checks    the   dis- 

If  difficulty  is  experienced  in  procuring  any  Squibb  product, 
in  the  original  packages  here  listed,  please  notify  us;  we 
shall  see  that  your  wants  are  met  promptly  and  satisfactorily. 


330        SQUIBB'S  MATERIA  MEDICA 

t  Tablets  Bismuth  Subgallate  Compound  No.  3,  Squibb 
(Cont.) 

charge.  Its  action  is  Antiseptic,  Anodyne  and  mildly  Astringent. 
Dose:  for  adults,  1  tablet,  every  two  or  three  hours;  for  chil- 
dren, 1  tablet  in  a  tablespoonful  of  water  and  a  teaspoonful  of 
the  solution  given  every  two  or  three  hours,  stirring  well  before 
each  dose. 

Tablets  Bismuth  Subnitrate  1  gr.,  Squibb 

C.T.  Per  1000  Per  500  Per  100 

Bismuth  subnitrate  is  used  in  dyspepsia,  to  control  nausea  and 
vomiting  and  to  prevent  flatulence  and  pyrosis.  It  is  found  use- 
ful in  the  chronic  gastritis  of  alcoholics,  in  gastralgia  and  in 
ulcer  of  the  stomach.  It  acts  as  a  Sedative  and  Astringent  in 
inflamed  conditions  of  the  mucosae  of  the  stomach  and  the 
intestines,  especially  when  of  a  catarrhal  nature.  Tablets  Bis- 
muth Subnitrate  Squibb  disintegrate  at  once  in  the  presence  of 
water,  and  yield  more  rapid  therapeutic  effects  than  capsules 
or  cachets.  If,  as  sometimes  happens  in  nausea,  it  is  inad- 
visable to  give  much  liquid,  a  tablet  may  be  placed  in  a  spoon 
and  a  few  drops  of  water  added.  Dose :  1  tablet  every  hour 
or  two,  in  diarrhea  and  vomiting  in  infants. 

Tablets  Bismuth  Subnitrate  2  gr.,  Squibb 

C.T.  Per  1000  Per  500  Per  100 

Dose:  1  tablet  every  half  hour  for  three  or  four  doses,  in 
stomach  and  intestinal  indigestion. 

Tablets  Bismuth  Subnitrate  5  gr.,  Squibb 

C.T.  Per  1000  Per  500  Per  100 

Dose:  for  nausea  and  indigestion,  1  or  2  tablets  after  meals; 
for  diarrhea,  1  or  2  tablets  every  three  hours  until  relieved. 

Tablets    Bitter  Tonic       (Dr.   Frank  E.  West).     See  Tablets 
Nux  and  Ipecac  Compound. 

Tablets   Blank,  Squibb 

Per  1000     Per  500       Per  100 
White,  Pink  or  Yellow  (T.  T.) 

These  tablets  are  made  from  Squibb's  pure  milk  sugar.  They 
contain  no  medicinal  ingredient  whatever.  The  pink  and  yellow 
tablets  are  prepared  with  vegetable  colors  which  are  perfectly 
harmless. 

Tablets  Blaud's  1  gr.,  Squibb 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 

The  iron  and  alkali  carbonate  exist  in  these  tablets  in  the  un- 
combined  state;  in  presence  of  moisture,  as  in  the  stomach, 
reaction  takes  place,  which  results  in  the  formation  of  ferrous 
carbonate.  Nascent  ferrous  carbonate  is  universally  conceded 
to  be  one  of  the  best  forms  in  which  iron  can  be  administered; 


SQUIBB'S  MATERIA  MEDICA        331 

Tablets  Blaud's  1  gr.,  Squibb  (Cont.) 

it  is  rapidly  acted  »pon  by  the  stomach,  easily  utilized,  produces 
a  marked  increase  in  the  quantity  of  hemoglobin  and  the  red 
corpuscles,  and  rarely  causes  any  constitutional  disturbances;  in 
anemia  and  debility  its  effects  are  soon  apparent  in  the  bettered 
nutrition  and  the  altered  state  of  the  blood.  Dose :  for  chil- 
dren, 1  or  2  tablets  after  meals,  continuing  the  treatment  as 
long  as  necessary. 

Tablets  Blaud's  3  gr.,  Squibb 

Per  1 000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 

Dose :  1  or  2  tablets  three  times  a  day,  after  meals,  until  the 
condition  is  improved. 

Tablets  Blaud's  5  gr.,  Squibb 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 
Dose :    1   tablet  three  times  a  day,  after  meals. 
Tablets  Blaud's  and  Manganese  Compound,  Squibb 
(Anemia) 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 

Blaud's  Mass  3  gr.  "I      Experience  has  shown  that  of 

Manganese  Dioxide  1  gr.  r      the  many  forms  of  iron  intro- 

Acid  Arsenous  I/go  gr.  J      duced     to     th«    medical     pro- 

fession,   ferrous    carbonate    in 

the  nascent  condition  is  one  that  is  best  borne  and  one  that 
yields  the  most  rapid  results;  its  administration  is  rarely  fol- 
lowed by  headache  or  disturbance  of  the  digestive  functions. 
The  arsenous  acid  and  manganese  are  believed  to  enhance 
the  therapeutic  action  of  the  iron.  They  are  employed  in  ane- 
mia, debility  and  menstrual  irregularities.  Dose :  1  or  2  tab- 
lets with  water,  after  meals. 

Tablets  Blaud's  Mass  and  Aloin  Compound,  Squibb 

(Blaud's   Tonic   Laxative) 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 
Pink-coated  (P.  C.  T.) 


Blaud's  Mass  3   gr 

Aloin  VlO  gr 

Quinine  Sulphate  1/2  gr 

Extract  Nux  Vomica  1/io  gr. 


These  tablets  have  been  used 
with  good  effect  in  anemic 
and  chlorotic  conditions  with 
disturbance  of  the  menstrual 


functions.  The  aloin  serves 
to  relieve  the  constipation  present  in  certain  patients.  Dose : 
1  or  2  tablets,  three  times  a  day,  after  meals. 

The  Squibb  products  are  recognized  everywhere  as  the  Quality 
Standard.  They  are  of  uniform  purity  and  strength,  hence 
therapeutically  dependable.  When  ordering  or  prescribing  med- 
icinal products,  you  will  do  well  always  to  specify  SQUIBB'S. 


332        SQUIBB'S  MATERIA  MEDICA 

Tablets  Blaud's  Pill  Compound,  Squibb 

Per  1 000,       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 

Blaud's  Mass  3  gr.  )      'The    arsenous    ackl     in     this 

Acid  Arsenous  */60  8r<  )       formula   is   added   to    increase 

its      therapeutic      value,       the 

combination  of  the  two  remedies  producing  a  more  rapid  and 
pronounced  effect  upon  the  blood.  It  is  indicated  in  anemia, 
debility  and  chlorosis.  Dose :  1  tablet  three  times  a  day,  with 
water,  after  meals. 

Tablets  Blaud's  Pill  Compound  No.  2,  Squibb 

Per  1000        Per  500        Per  100 

Chocolate-coated  (C.  C.  T.) 

Blaud's  Mass  5  gr.  \      Same  indications  as  preceding. 

Acid  Arsenous  i/40  gr.  }       Dose :     I    tablet,    after   meals, 

with  water. 

Tablets  Blaud's  PHI  Compound  No.  3,  Squibb 

Per  1000   Per  500   Per  100 

Chocolate-coated  (C.  C.  T.) 

Blaud's  Mass  5  gr.  "1       These  tablets  are  employed  in 

Mercury  Bichloride  I/go  gr.  I  anemia,  chlorosis  and  general 
Strychnine  Sulphate  Voo  gr-  f  debility.  Dose:  1  tablet 
Acid  Arsenous  J/so  gr. J  three  times  a  day,  after 

meals,     with     a     swallow     of 
water  or  other  beverage. 

Tablets  Blaud's  Pill  Compound  No.  3,  Half   Strength, 
Squibb  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 

Blaud's  Mass  21/2  gr.  ]  For  indications,  see  preceding. 

Mercury  Bichloride  1/100  gr.  I  Dose:     1     or    2    tablets    three 

Strychnine  Sulphate  1/120  gr.  J  lmies   a   day>    after   meals. 

Acid  Arsenous  /100  §r-  J 

Tablets  Blaud's  Pill  Compound  No.  4,  Squibb 

(Tonic,  Children's) 

Per  1000       Per  500       Per  100 
Pink-coated  (P.  C.  T.) 

Blaud's  Mass  1  gr.  1       The  effects  of  iron  in  anemic 

Quinine  Sulphate  VlC  8r*  I       anc^   debilitated   conditions   are 

Acid  Arsenous  1/500  gr-  r      nere   intensified   by   alteratives. 

Strychnine  Sulph.  V.'iOO  8r<  an(^  other  tonic  remedies, 
Corrosive  Sublim.  1/400  gr-  J  thereby  effecting  improvement 

of     the     appetite,     assimilation 

and  nutrition,  while  the  anemic  condition  gradually  disappears. 
Dose :  I  or  2  tablets,  according  to  age  of  child,  after  meals. 


SQUIBB'S  MATERIA  MEDICA        333 

Tablets  Blaud's  Pill  Compound  Improved,  Squibb 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 

Blaud's  Mass  5  gr.  "1       As    a    well-made    tablet    con- 

Acid  Arsenous  1/50  gr.  1       taining    Blaud's    Mass    rarely 

Extract  Nux  Vomica  Vg  gr.  f  "produces  constipation,  the 
Extract  Cascara  Sagr.  J/2  8r>  J  addition  of  extract  cascara 

sagrada      in        this       formula 

might  seem  unnecessary.  However,  occasionally  there  are  cases 
where  obstinate  constipation  exists  in  anemic  patients,  and  in 
such  these  tablets  are  used  to  special  advantage.  Dose :  1  tablet. 

Tablets  Blaud's  Tonic  Laxative.        See     Tablets     Blaud's 
Mass  and  Aloin  Compound. 

Tablets  Blue  Mass  5  gr.,  Squibb 

Per  1000  Per  500  Per  100 

C.T. 

These  tablets  are  made  from  the  Well-known  Squibb  Massa 
Hydrargyri,  in  which  special  care  is  taken  to  thoroughly  sub- 
divide the  mercury,  and  upon  which  the  efficiency  and  uniform 
action  of  the  product  depend.  The  mass  is  in  no  way  altered 
by  the  process  of  transforming  into  tablets.  Squibb's  Blue  Mass 
Tablets  are  to  be  preferred  to  pills  of  blue  mass  because  they 
do  not  harden  with  age;  moreover,  they  disintegrate  promptly 
in  water,  and  retain  their  therapeutic  action  indefinitely.  Dose : 
I  or  2  tablets  at  night,  followed  next  morning  by  a  saline 
cathartic. 

Tablets     Borax     and     Sodium     Salicylate     Compound, 
Squibb  (Antiseptic  Detergent) 

Bots.  of  50 

Per  500  Per  100  Per  doz. 

C.T. 

These  tablets  are  a  convenient  means  for  preparing  antiseptic 
solutions.  They  contain  sodium  bicarbonate  (41/o  gr.),  sodium 
borate  (41/o  gr.),  sodium  salicylate  (Vll  gr.),  eucalyptol,  men- 
thol and  methyl  salicylate.  They  are  non-poisonous  and  when 
dissolved  in  the  proportion  of  1  tablet  in  2  fluidounces  of  water, 
yield  a  bland  detergent  fluid  with  mild  antiseptic  powers,  which 
is  a  slight  modification  of  the  solution  originally  proposed  by 
Dr.  Carl  Seiler.  They  have  been  found  very  efficacious  as  a 
spray  or  douche  in  acute  or  chronic  catarrh,  as  a  gargle  in  sore 
throat,  and  as  a  mouth  wash. 


Since  we  make  only  one  quality  of  each  product,  that  best 
suited  to  the  purposes  intended,  the  specification  "Squibb's" 
is  not  open  to  various  interpretations,  but  has  a  plain,  positive 
meaning.  When  ordering  or  prescribing,  specify  SQUIBB'S. 


334        SQUIBB'S  MATERIA  MEDICA 

Tablets     Borax     and     Sodium     Salicylate     Compound, 
,      Improved,  Squibb      (Antiseptic  Detergent  Improved) 

Bots.  of  50 

C.T.  Per  500  Per  100  Per  doz. 

These  tablets  are  preferred  where  a  slight  astringent  effect  upon 
the  mucous  membrane  is  desired.  They  contain  in  addition  to 
the  ingredients  of  the  preceding  antiseptic  tablets,  sanguinarine 
nitrate  (Veo  gr.)  and  hydrastine  hydrochloride  (1/]20  gr.)  5 
these  lend  stimulating  and  astringent  properties  to  the  combina- 
tion. For  preparing  a  spray,  nasal  douche  or  mouth  wash, 
dissolve  1  tablet  in  2  fluiclounces  of  water. 

Tablets    Bromides    Compound.       (Dr.    Hubbard).      See 
Tablets    Morphine    and    Hyoscine    Hydrobromides    Compound. 

Tablets  Bromides,  Triple.       See  Tablets  Triple  Bromides. 

Tablets  Bronchitis.       See  Tablets  Dover's  Powder  and  Bella- 
donna Compound. 

Tablets  Bronchitis  No.  2  (Acute).       See    Tablets    Aconite 
and  Belladonna  Compound  No.  2. 

f*  Tablets  Brown  Mixture,  Squibb 

(One  leaspoonful) 

Per  1000  Per  500  Per  100 

T.  T. 


Extract  Licorice  1/io  gr. 

Camphor  1/35  gr. 

Acid  Benzoic  */25  gr. 

Oil  Anise  1/05  min. 

Opium  Powdered  1/25  gr. 

Tartar  Emetic  i/GO  gr. 


Brown  Mixture  has  long 
been  a  popular  remedy  in 
treatment  of  coughs  with  hot, 
dry  skin,  scanty  expectora- 
tion, hoarseness  and  difficult 
breathing.  It  owes  its  virtue 


largely  to  the  small  quantity 
of  tartar  emetic  it  contains,  which  by  its  action  upon  bronchial 
mucous  membrane  and  the  skin  tends  to  relieve  the  cough  and 
oppression  and  to  increase  expectoration.  These  tablets  are 
used  chiefly  in  children  over  two  years  old.  Dose :  1  tablet 
every  hour  until  the  acute  symptoms  are  relieved  or  slight 
nausea  occurs,  and  then  at  longer  intervals. 

f  Tablets  Brown  Mixture  Compound,  Squibb 

Per  1000     Per  500     Per  100 

C.T. 

Brown  Mixture  I  fl.  dr.  \      The    addition    of    ammonium 

Ammonium  Chloride          1  gr.  )       chloride  to  this  formula  serves 

to      increase      its      expectorant 

effect  and  to  counteract  in  a  measure  the  depressant  action  of 
the  tartar  emetic.  It  is  considered  an  excellent  remedy  in 
coughs  and  colds  with  painful  and  scanty  expectoration  of  viscid 
mucus.  Dose :  1  tablet,  allowed  to  dissolve  in  the  mouth  or 
taken  with  a  swallow  of  water,  every  hour  or  two  until  symp- 
toms improve,  and  then  at  longer  intervals. 


SQUIBB'S  MATERIA  MEDICA        335 

Tablets  Buchu  Compound,  Squibb 

(Infusion   Buchu  Compound) 

Per  1000  Per  500  Per  100 

C.T. 

Each  tablet  represents*: 


Infusion  Buchu  3  dr. 

Tr.  Hyoscyam.  UJS.P.  '90 


20 


mm. 


Potassium  Bicarbonate      6  gr. 


Irritable  conditions  of  the 
bladder  and  urethra,  and 
cystitis  with  acid  urine,  are 
reported  to  be  markedly  re- 


lieved by  the  use  of  these 
tablets;  the  bicarbonate  of  potassium  neutralizing  acidity,  re- 
ducing inflammation,  increasing  the  action  of  the  kidneys  and 
exerting  a  solvent  action  upon  uric  acid  calculi.  Hyoscyamus 
allays  pain  and  tenesmus,  and  quiets  the  irritable  state  of  the 
bladder.  Buchu  is  regarded  as  a  diuretic  and  stimulant  to 
the  mucous  membranes  of  the  genito-urinary  organs.  It  is  said 
to  reduce  inflammation,  to  increase  the  secretion  of  the  kidney 
when  scanty,  and  to  render  it  bland  and  non-irritating.  Tab- 
lets Buchu  Compound  Squibb  have  been  found  useful  and  to 
afford  prompt  relief  in  vesical  and  urefhral  inflammation 
with  strongly  acid  urine;  in  mild  disorders  caused  by  cold  or 
disturbed  digestion  with  painful  and  frequent  micturition;  in 
subacute  gonorrhea  and  enlarged  prostate;  and  in  the  atonic 
conditions  of  the  bladder  in  elderly  men,  with  incontinence  or 
retention  of  urine.  Dose :  1  or  2  tablets,  with  a  glass  of  hot 
water,  every  three  or  four  hours. 


Tablets  Caffeine  1  gr.,  Squibb 

Per  1000  Per  500  Per  100 

T.  T.  ^ 

Caffeine  is  believed  to  strengthen  the  cardiac  contractions  and 
increase  arterial  pressure;  also  to  act  directly  upon  the  kidneys. 
Hence  it  is  used  as  a  Cardiac  and  Renal  Stimulant,  as  a  stim- 
ulant to  the  cerebral  functions,  and  also  as  an  antidote  in  mor- 
phine poisoning.  Dose : .  1  tablet  three  or  four  times  a  day. 

Tablets  Caffeine  Citrated  1  gr.,  Squibb 

Per  1000  Per  500  Per  100 

T.  T. 

Dose:  1  tablet  three  or  four  times  a  day,  as  a  Cardiac  and 
Renal  Stimulant. 


The  founder  of  the  House  of  Squibb,  Dr.  Edward  R.  Squibb, 
not  only  had  high  ideals,  but  lived  and  labored  for  them;  and, 
in  the  words  of  William  Miller  Bartlett,  "the  House  of  Squibb 
stands  today  as  a  living  monument  to  the  honor,  integrity,  zeal 
and  devotion  of  its  founder." 


336        SQUIBB'S  MATERIA  MEDICA 

Tablets  Caffeine  Compound,  Squibb 

Per  1 000          Per  500          Per  100 
T.  T. 

Caffeine  Citrated  I    gr.  \      This  combination  is  used  with 

Nitroglycerin  ^/200  gr«  I     good  effects  in  cardiac  dilata- 

tion  and   in   affections   of   the 

kidneys.  According  to  clinical  observation,  it  supports  the  heart, 
lowers  arterial  tension  and  increases  the  urinary  secretion,  and 
is  useful  in  relieving  the  headaches  in  contracted  kidney  and  in 
increasing  the  flow  of  urine  in  acute  parenchymatous  nephritis. 
Dose :  I  tablet  three  or  four  times  a  day. 

Tablets  Calcium  Sulphide  1/20  gr.,  Squibb 

Per  1000     Per  500     Per  100 
Chocolate-coated  (C.  C.T.) 

Calcium  sulphide  (so-called;  more  correctly,  sulphurated  lime) 
is  said  to  check  suppuration  and  inflammation,  and  has  been 
used  in  the  treatment  of  boils,  acne,  carbuncles,  discharges 
from  the  ear,  conjunctivitis,  enlarged  glands,  chronic  bronchitis 
with  purulent  secretion,  etc.  As  the  drug  is  unpleasant  to  the 
taste  and  smell,  the  tablets  are  offered  in  chocolate-coated  form 
only.  Dose:  1  to  3  tablets  after  meals. 

Tablets  Calcium  Sulphide  1/10  gr.,  Squibb 

Per  1000     Per  500     Per  100 
Chocolate-coated  (C.  C.  T.) 

Dose:  1  or  2  tablets  every  two  or  three  hours,  for  boils,  car- 
buncles and  other  suppurative  conditions. 

Tablets  Calcium  Sulphide  %  gr.,  Squibb 

Per  1000     Per  500     Per  100 
Chocolate-coated  (C.  C.  T.) 

Dose:   1   or  2  tablets  every  two  or  three  hours. 

Tablets  Calcium  Sulphide  yz  gr.,  Squibb 

Per  1000     Per  500     Per  100 
Chocolate-coated  (C.  C.  T.) 

Dose :  1  tablet  three  or  four  times  a  day,  for  boils,  carbuncles, 
etc. 

Tablets  Calcium  Sulphide  1  gr.,  Squibb 

Per  1000     Per  500      Per  100 
Chocolate-coated  (C.  C.  T.) 

Dose:  1  tablet  three  or  four  times  a  day,  for  boils,  carbuncles, 
etc. 


SQUIBB'S  MATERIA  MEDICA        337 

*  Tablets  Calomel  1/100  gr.,  Squibb 

Per  1000  Per  500  Per  100 

T.  T. 

Small  doses  of  calomel  are  regarded  as  valuable  in  disordered 
states  of  the  alimentary  canal,  whether  associated  with  diarrhea 
or  with  constipation.  In  diarrhea  with  clay-colored  feces,  di- 
geslive  disturbance  and  febrile  symptoms  it  has  been  found  to 
act  remarkably  well,  changing  the  color  and  character  of  the 
stools,  relieving  the  dyspepsia,  and  allaying  the  restlessness  and 
fever.  Small  doses  repeated  until  the  desired  effect  is  obtained 
seem  to  accomplish  as  much  as  larger  ones,  with  less  systemic 
disturbance.  Careful  trituration  is  one  of  the  prominent  features 
of  Tablets  Calomel  Squibb,  resulting  in  accurate  dosage  and 
uniform  therapeutic  action.  Dose:  for  an  infant,  1  tablet  every 
hour  or  two  until  symptoms  improve. 

*  Tablets  Calomel  1/20  gr.,  Squibb 

Per  1000  Per  500  Per  100 

T.  T. 

Dose:  1  tablet  every  hour  until  bowels  act  and  character  of  the 
secretions  changes. 

Tablets  Calomel  1/10  gr.,  Squibb 

Per  1000  Per  500  Per  100 

T.  T.  or  C.  T. ;  Plain,  Pink, 
Rose  or  Wintergreen  Flavor 

Dose :  1  tablet  every  hour  for  adults  or  children,  for  ten  doses 
or  until  the  bowels  move  freely,  as  an  Hepatic  Stimulant  and 
Corrective. 

*  Tablets  Calomel  %  gr.,  Squibb 

Per  1000  Per  500  Per  100 

T.  T.,  Plain  or  Winter- 
green  Flavor 

Dose :  1  tablet  every  hour  until  bowels  move  or  until  eight 
have  been  taken,  followed  by  a  saline  cathartic. 

*  Tablets  Calomel  1/6  gr.,  Squibb 

Per  1000  Per  500  Per  100 

T.  T.,  Plain  or  Winter- 
green  Flavor 

DOSE:  1  tablet  every  hour  until  six  tablets  have  been  taken; 
the  last  dose  being  followed  by  a  saline  cathartic. 


The  Squibb  Ideals  have  taken  concrete  form  in  the  Squibb 
Products;  these  are  universally  recognized  as  standards  of 
uniform  Purity  and  Efficacy,  that  is,  general  Excellence  and 
Reliability,  Specify  SQUIBB'S  when  prescribing  or  ordering. 


338        SQUIBB'S  MATERIA  MEDICA 

'Tablets  Calomel  1/5  gr.,  Squibb 

Per  1000  Per  500  Per  100 

T.  T.,  Plain  or  Winter- 
green  Flavor 

Dose:    1    tablet  every  hour  until  bowels  move   freely;    the  last 
.  dose  being  followed  by  a  saline  laxative. 

*  Tablets  Calomel  J4  gr.,  Squibb 

Per  1000  Per  500  Per  100 

T.  T.,  Plain  or  Winter- 
green  Flavor 

Dose:  1  tablet  every  hour  or  two  until  laxative  action  is  ob- 
tained, followed  by  a  saline  cathartic.  In  dyspepsia  with  coated 
tongue,  1  or  2  at  night  followed  by  a  saline  cathartic  next 
morning. 

*  Tablets  Calomel  ^  gr.,  Squibb 

Per  1000  Per  500  Per  100 

T.  T.,  Plain  or  Winter- 
green   Flavor 

Dose:  1  tablet  every  hour  or  two  until  effect  is  produced,  fol- 
lowed by  a  saline  cathartic. 

*  Tablets  Calomel  1  gr.,  Squibb 

Per  1000  Per  500  Per  100 

T.  T.,  Plain  or  Winter- 
green  Flavor 

Dose :  1  tablet  every  two  or  three  hours  until  laxative  action  is 
obtained,  followed  by  a  saline  cathartic. 

Tablets  Calomel  2  gr.,  Squibb 

Per  1000  Per  500  Per  100 

T.  T.,  Plain  or  Winter- 
green  Flavor 

Dose :  1  or  2  tablets  at  night,  followed  next  morning  by  a 
saline  cathartic. 

Tablets  Calomel  5  gr.,  Squibb 

C.  T.  Per  1000  Per  500  Per  100 

Dose :  1  tablet  at  night,  followed  by  a  saline  cathartic  next 
morning. 

*  Tablets  Calomel  and  Bismuth  Compound,  Squibb 

(Corrective   Infants',   Dr.   Ives) 
T.  T.  Per  1 000  Per  500  Per  100 


Calomel  1/20  8r- 

Bismuth    Subnitrate  1  gr. 

Sodium    Bicarbonate  l/o  gr. 

Ipecac    _  VoO  gr. 

Oil    Anise  q.  s. 


Attacks  of  indigestion  in  chil- 
dren due  to  overeating,  with 
coated  tongue,  foul  breath  and 
fever,  have  been  quickly  re- 
lieved by  the  use  of  this 


formula.     Calomel  and  ipecac 
are  intended   to  increase   the  activity  of   the   liver,   and   by  their 


SQUIBB'S  MATERIA  MEDICA        339 

*  Tablets    Calomel    and    Bismuth    Compound,    Squibb 
(Cont.) 

action  upon  the  bowels  to  relieve  the  overburdened  system. 
Bismuth  subnitrate  and  sodium  bicarbonate  tend  to  correct  the 
dyspepsia  and  hyperacidity.  Dose :  1  tablet  in  a  teaspoonful 
of  water  every  hour  or  two  until  relieved. 

f  Tablets  Calomel  and  Morphine  Compound,  Squibb 

(Diarrhea  No.  2) 

Per  1000     Per  500     Per  100 
Chocolate-coated  (C.  C.  T.) 


Calomel  */8  gr. 

Morphine  Sulphate     Vie  gr- 

Capsicum  VlG  gr. 

Ipecac  1/32  gr. 

Camphor  Vie  8r- 


This  formula  has  been  in  use 
many    years    in    the    treatment 


of  summer  diarrhea,  especially 
where  after  expulsion  of  the 
exciting  irritants,  the  discharge 
continues,  and  where  a  condi- 
tion bordering  on  dysentery  exists.  Dose :  1  tablet  with  water 
every  hour  for  three  or  four  doses,  then  every  two  or  three 
hours  until  relieved. 

Tablets  Calomel  and  Santonin.     See  Tablets  Santonin  and 
Calomel. 

Tablets  Calomel  and  Soda,  Squibb 

Per  1000     Per  500     Per  100 
C.T. 
Chocolate-coated  (C.  C.  T.) 

Calomel  l/o  gr. )       The    combination    of    calomel 

Sodium    Bicarbonate        3  gr.  j      with    an    alkali    is    a    favorite 

method    of    administering    this 

remedy  in  attacks  of  diarrhea  in  children  where  the  movements 
are  slimy  and  green-colored.  These  tablets  are  used  also  as 
a  stimulant  to  the  liver  in  sluggishness  of  that  organ  in  adults. 
Dose :  for  children  with  diarrhea,  1  tablet  every  two  hours, 
until  the  character  of  the  discharges  changes;  for  adults,  1  or 
2  tablets  at  night. 

*  Tablets  Calomel  and  Soda  No.  2,  Squibb 

Per  1000  Per  500  Per  100 

T.  T. 

Calomel  1/4  gr.  )       This    formula    is    largely   used 

Sodium  Bicarbonate          1  gr.  )       in     deranged     and     congested 

conditions   of    the   liver   where 

the  symptoms  of  poor  appetite,  coated  tongue,  bad  breath, 
headache  and  constipation  are  present.  Dose :  1  tablet  every 
hour  until  laxative  effect  is  produced. 


The  Squibb  Label  on  a  package  is  a  positive  guaranty  for  the 
uniform  Purity  and  Reliability  of  the  product.  We  make  only 
ONE  quality:  the  SQUIBB  quality;  and  our  prices  are  as  low 
as  they  can  be  made  for  that  quality.  Specify  SQUIBB'S. 


340        SQUIBB'S  MATERIA  MEDICA 

Tablets  Calomel  and  Soda  No.  3,  Squibb 

Per  1000  Per  500  Per  100 

T.  T. 

Calomel  1/g  gr.  \      Dose !     1     tablet    every     hour 

Sodium  Bicarbonate          1  gr.  )      until   bowels  move. 

Tablets  Calomel  and  Soda  No.  4,  Squibb 

Per  1000  Per  500  Per  100 

C.  T. 

Calomel  !/6  gr.  \      Dose :     1     tablet    every     hour 

Sodium    Bicarbonate         I  gr.  }      until  bowels  move,  or  until  six 

doses    have    been    taken,    fol- 
lowed by  a  saline  cathartic. 


Tablets  Calomel  and  Soda  No.  5,  Squibb 

Per  1000  Per  500  Per  100 

T.  T. 

Calomel 

Sodi  „     ., 

a  saline  cathartic. 


lomel  1/5  gr.  )       Dose :     1     tablet    hourly     for 

i'mm   Bicarbonate         1  gr.  }       about  five  doses,   followed  by 


Tablets  Calomel  and  Soda  No.  6,  Squibb 

Per  1000  Per  500  Per  100 

T.  T. 

Calomel  1/2  gr.  1       Dose :     1      tablet     every     two 

Sodium    Bicarbonate         1  gr.  )      hours  for  three  or  four  doses, 

followed  by  a  saline  laxative. 
« 
Tablets  Calomel  and  Soda  No.  7,  Squibb 

Per  1000  Per  500  Per  100 

T.  T. 

Calomel  l/o  gr.  1       Dose :     1     tablet     hourly     for 

Sodium    Bicarbonate      1/2  gr.  j       three  or   four   doses,   followed 

by  a  saline  cathartic;   or  2  to 
4  tablets  at  bedtime,  followed  by  a  saline  purge  next  morning. 

Tablets  Calomel  and  Soda  No.  8,  Squibb 

Per  1000         Per  500         Per  100 
C.  T. 

Calomel  2  gr.  1       Dose :   1    or  2  tablets  at  night, 

Sodium    Bicarbonate        2  gr.  }       followed    next    morning    by    a 

saline   laxative. 

Tablets  Calomel  and  Soda  No.  9,  Squibb 

Per  1000  Per  500  Per  100 

T.  T. 

Calomel  1/4  gr.  ]      Dose :  1   tablet  every  hour  for 

Soduim    Bicarbonate      1/4  gr.  J      four  doses,  or  4  tablets  at  bed- 
time, as  above. 


SQUIBB'S  MATERIA  MEDICA       341 

Tablets  Calomel  and  Soda  No.  10.         See    Tablets    Calo- 
mel Compound. 

Tablets  Calomel  and  Soda  No.  11.     See     Tablets     Calomel 
Compound  No.  2. 

Tablets  Calomel  and  Soda  No.  12.    See     Tablets     Calomel 
Compound  No.  3. 

*  Tablets  Calomel  Compound,  Squibb 

(Calomel   and  Soda   No.    10) 

Per  1000     Per  500     Per  100 
T.T. 
Chocolate-coated  (C.  C.  T.) 

Calomel  Vio  gr.  j      These  tablets  are  liable  to  be- 

Sodium  Bicarbonate          1  gr.  j       come    discolored    on    exposure 

to    dampness.       The     change, 

however,  in  no  way  affects  the  therapeutic  value  of  the  com- 
bination, and  corresponds  to  the  decomposition  which  occurs  in 
the  system.  It  may  be  retarded  by  keeping  the  bottle  well 
corked  and  in  a  dry  place.  Dose :  1  tablet  every  hour  until 
laxative  action  is  obtained. 

*  Tablets  Calomel  Compound  No.  2,  Squibb 

(Calomel   and  Soda   No.    II) 

Per  1000  Per  500  Per  100 

T.  T. 

Calomel  1  gr.  {      Dose :  1    or  2  tablets,  at  night, 

Sodium    Bicarb.  1  gr.  3       for     several     doses,     gradually 

decreasing  as  symptoms  im- 
prove. In  torpid  liver,  coated  tongue  and  jaundice  in  the  early 
stages,  the  use  of  laxative  mineral  waters,  or  some  saline  laxa- 
tive dissolved  in  a  large  quantity  of  water,  is  continued  during 
the  treatment,  a  sufficient  dose  being  given  to  move  the  bowels 
freely  every  morning. 

*  Tablets  Calomel  Compound  No.  3,  Squibb 

(Calomel   and  Soda   No.    12) 

Per  1000  Per  500  Per  100 

T.  T. 

Calomel  !/4  gr.  1      The    favorite    combination    of 

Sodium  Bicarbonate  1/2  gr-  f  calomel  and  soda  is  here 
Podophyllin  1/12  gr.  J  modified  by  the  addition  of 

podophyllin,     which     increases 

its  cholagogue  effect.  The  formula  is  indicated  where  a  pro- 
nounced impression  upon  the  hepatic  function  is  desired,  but 
it  is  not  used  where  inflammatory  conditions  of  the  intes- 


Squibb's  Tablets  are  made  from  the  Squibb  quality  of  ingredients 
and  by  improved  processes  that  insure  accurate  dosage  and 
rapid  and  complete  disintegration  or  solution  in  the  system, 
hence  prompt  and  full  therapeutic  effect.  Specify  SQUIBB'S. 


342        SQUIBB'S  MATERIA  MEDICA 

*  Tablets   Calomel   Compound   No.   3,   Squibb    (Cont.) 

tinal  tract  are  present.  In  that  state  known  as  "biliousness," 
with  coated  tongue,  bad  breath,  disordered  bowels,  flatulence, 
and  nervous  headache,  it  usually  operates  with  benefit.  In  early 
attacks  of  jaundice  it  has  been  used  with  generally  good  results. 
Occasionally  through  exposure  to  dampness  these  tablets  become 
discolored.  However,  this  change,  which  is  similar  to  that 
which  takes  place  in  the  system,  does  not  interfere  with  their 
therapeutic  effect.  Dose:  1  or  2  tablets  at  night,  followed  by 
a  saline  laxative  next  morning;  or  I  tablet  every  3  hours  until 
they  operate. 

*  Tablets  Calomel,  Ipecac  and  Soda,  Squibb 

Per  1000  Per  500  Per  100 

T.  T. 

Calomel  1/5  gr.  "1       The     addition     of    ipecac     to 

Ipecac  i/io  gr.  >      calomel  is  intended  to  increase 

Sodium    Bicarbonate         I  gr.  J       its   usefulness    in    disorders   of 

the  stomach,  in   that  condition 

known  as  "biliousness."  These  tablets  are  employed  in  indi- 
gestion, with  coated  tongue,  headache  and  constipation.  Dose : 
1  or  2  tablets,  after  meals,  with  an  occasional  dose  of  a  saline 
aperient  in  the  morning — enough  to  produce  a  free  movement, 
but  not  sufficient  to  purge. 

Tablets  Camphor  and  Hyoscyamus  Compound,  Squibb 

(Nervine) 

Per  1 000     Per  500     Per  100 
Chocolate-coated  (C.  C.  T.) 

Camphor  1  gr.  1       This  formula  acts  as  an  Ano- 

Ext.  Hyoscyamus  1/2  gr.  >  dyne  and  Sedative  to  the  ner- 
Ext.  Valerian  l/o  gr.  J  vbus  system.  It  is  used  in 

controlling  mild  mental  excite- 
ment, quieting  the  sexual  system  and  for  inducing  sleep  in  in- 
somnia due  to  cerebral  stimulation  caused  by  overwork  or  worry; 
also  to  allay  pain  and  restlessness  due  to  vesical  irritation. 
Dose:  1  tablet  every  half  hour  for  three  or  four  doses,  then 
every  two  hours  until  effect  is  produced. 

Tablets  Camphor  and  Opium.    See      Tablets     Opium     and 
Camphor. 

Tablets  Camphor,  Hyoscyamus  and  Sumbul  Compound, 
Squibb  (Sedative  No.  2) 

Per  1000     Per  500     Per  100 
White-coated  (W.  C.  T.) 

Camphor  I  gr.    )     For  nervous  and  excited  states 

Ext.  Hyoscyamus  1/o  gr.     (     of  the  system  caused  by  over- 

Ext.  Sumbul  */2  gr.     |     work,   loss  of  sleep  or  worry; 

Valerian  1/2  gr.    J     in   mild   forms   of   melancholia 

and  hysteria;  and  to  allay 
sexual  excitement.  Dose:  1  tablet  after  meals  and  at  bedtime. 


SQUIBB'S  MATERIA  MEDICA        343 


Tablets  Cannabis  Extract  %  gr.,  Squibb 

T.  T.  Per  1000          Per  500  Per  100 

Cannabis  has  been  employed  as  a  Sedative,  Anodyne  and 
Hypnotic,  in  cases  where  opium  does  not  agree  with  the  patient. 
Unlike  the  latter,  it  causes  neither  nausea  nor  constipation.  It 
produces  at  first  a  mental  stimulation,  which  is  later  followed 
by  a  calmer  mood  and  finally  by  sleep.  It  is  used  in  acute 
and  chronic  mental  derangements,  in  neuralgia,  migraine,  gout 
and  rheumatism.  In  combination  with  the  bromides  (see  Tab- 
lets Triple  Bromides  and  Cannabis  Compound)  it  is  employed 
•in  hysteria,  delirium  tremens  and  mild  cases  of  mania.  All 
patients  do  not  respond  to  it  alike;  and  while  no  doubt  idiosyn- 
crasy plays  a  great  part,  yet  the  quality  of  the  drug  has  much 
to  do  with  its  constitutional  effect.  In  all  our  preparations  of 
this  drug  the  best  quality  of  hemp  is  used.  The  results  will  be 
found  uniform  and  reliable.  Dose:  1  tablet  every  2  or  3  hours. 

f  Tablets  Cannabis  and  Aconite  Compound,  Squibb 

(Neuralgic,  Brown-Sequard) 

Per  1000       Per  500       Per  100 
Chocolate  coated  (C.  C.T.) 


2/3  gr 
2/3  gr 


This  is  a  combination  of 
powerful  antispasmodics  and 
sedatives,  and  should  be  used 
with  caution.  All  of  the  ex- 
tracts are  accurately  standard- 
ized and  carefully  incorpo- 
rated in  the  tablets  which  rep- 
resent the  full  therapeutic 
efficiency  of  the  formula. 

Dose:    1    tablet  cautiously  repeated  every  three  or   four  hours; 

to  be  discontinued  after  the  third  dose. 


Extract  Cannabis 
Extract  Aconite 
Extract  Hyoscyamus 
Extract  Conium 
Extract  Ignatia 
Extract    Opium 
Extract  Stramonium 
Extract  Belladonna 


f  Tablets     Cannabis 
Strength,  Squibb 

(Neuralgic, 

Chocolate-coated 
Extract   Cannabis 
Extract  Aconite 
Extract   Hyoscyamus 
Extract.  Conium 
Extract  Ignatia 
Extract  Opium 
Extract  Stramonium 
Extract  Belladonna 


and     Aconite     Compound,     Half 

Brown-Sequard,  Half  Strength) 

Per  1000     Per  500     Per  100 

(C.  C.  T.) 

1/8  gr.  These  tablets  are  half  the 
1/6  gr.  strength  of  the  preceding  and 
1/3  gr.  are  intended  for  patients  of 
Vs  gr.  less  robust  constitution.  Dose  : 
1/4  gr.  1  tablet  every  three  or  four 
1/4  gr.  hours  with  a  swallow  of  water, 

!/10  gr.         but    to    be    discontinued    after 

1/12  gr.  J       the   third   dose. 


This  house  supplies  only  one  quality  of  each  product:  that  best 
suited  to  the  purposes  intended.  The  specification  "Squibb's" 
is  not  open  to  various  interpretations;  it  has  a  plain,  posi- 
tive meaning.  Therefore,  when  prescribing,  specify  SQUIBB'S. 


344        SQUIBB'S  MATERIA  MEDICA 

f  Tablets  Cannabis  and  Hyoscyamus  Compound,  Squibb 

(Croup,  Spasmodic) 

Per  1000  Per  500  Per  100 

C.  T. 


Extract  Cannabis  1/20  gr. 

Ext.  Hyoscyamus  VOQ  gr- 

Paregoric  5  mm. 

Syrup   Ipecac  5  min. 

Ext.   Licorice  2  gr. 


These  tablets  are  employed 
for  the  relief  of  laryngeal 
spasm  as  seen  in  croup  in  chil- 
dren. The  formula  is  an  old 
one  and  has  been  added  to 


our  list  in  response  to  repeated 
demands  from  physicians  who  have  used  it  with  good  results. 
Dose:  1  teaspoonful  of  a  mixture  of  eight  tablets  diffused  in 
twenty-five  teaspoonfuls  of  hot  water  every  fifteen  minutes  until 
relieved,  for  a  child  six  month*;  older  children  in  propor- 
tion. 

Tablets  Cannabis  and  Strychnine  Compound,  Squibb 

Per  1000     Per  500     Per  100 
Green-coated  (G.  C.  T.) 

Extract  Cannabis  VlO  gr.  1  This  combination  has  been 
Strychnine  Phosphate  1/4o  gr.  I  used  largely  as  a  nerve  tonic 
Zinc  Phosphide  1/io  gr.  |  and  stimulant.  It  is  indicated 

Avenin  V200  gr-  J       'n  anemic  and  debilitated  con- 

ditions of  the  system,  accom- 
panied with  lack  of  nervous  energy  and  of  vital  powers.  Dose : 
1  tablet  after  meals  and  at  bedtime. 

Tablets  Capsicum  and  Nux,  Squibb 

(Capsicum   Compound,   Dr.   Lindsley) 

Per  1000     Per  500     Per  100 
T.T. 

Chocolate-coated  (C.  C.  T.) 

Capsicum  1/io  gr.  7      Capsicum    stimulates    the    mu- 

Nux   Vomica  */4  gr-  j       cous  membranes  of  the  mouth 

and  the  stomach.     Nux  vomica 

is  of  value  in  all  atonic  conditions  of  the  alimentary  canal.  To- 
gether they  are  deemed  an  excellent  combination  for  disordered 
digestion  in  persons  of  sedentary  habits,  and  in  gastritis  due 
to  abuse  of  alcohol.  Dose:  1  or  2  tablets  half  an  hour  before 
•  meals,  repeated  if  necessary  at  half  hourly  intervals  for  three 
doses  after  eating. 

Tablets  Capsicum  and  Quinine.     See   Tablets   Quinine   and 
Capsicum. 

Tablets    Capsicum    Compound     (Dr.    Lindsley).     See    Tab- 
lets Capsicum  and  Nux. 

Tablets  Cardiac  (Dr.  Waldstein).   See  Tablets  Sparteine  Comp. 

Tablets  Cardiac  Asthma.      See    Tablets     Heroin     and     Digi- 
talis Compound. 


SQUIBB'S  MATERIA  MEDICA        345 

Tablets  Cascara  and  Bismuth.        See  Tablets  Bismuth  and 
Cascara. 

Tablets  Cascara  Compound,  Squibb 

C.T.  Per  1 000     Per  500     Per  100 

Chocolate-coated  (C.  C.  T.) 

Ext.  Cascara  Sagrada  2  gr.  "|  The  laxative  action  of  cascara 
Podephyllin  1/8  gr.  >  sagrada  is  here  increased  by 

Ext.  Belladonna  1/ie  gr.  J       the    addition    of    podophyllin, 

an  active  cathartic  and  hepatic 

stimulant,  and  modified  by  extract  belladonna,  which  prevents 
griping.  These  tablets  are  employed  as  a  Laxative  in  cases 
of  constipation  with  inactive  liver,  where  no  inflammation  of 
the  bowels  exists.  Dose:  1  or  2  tablets  at  night. 

Tablets  Cascara  Compound  No.  2,  Squibb 

(Dr.   Hinckle) 

C.  T.  Per  1000  Per  500  Per  100 

Pink-coated  (P.  C.T.) 


Cascarin  1/4  gr. 

Aloin  1/4  gr. 

Podophyllin  1/e  gr. 

Ext.    Belladonna  1/g  gr. 

Strychnine  Sulphate  1/co  gr. 

Gingerin  1/g  gr. 


All  parts  of  the  intestinal 
tract  are  said  to  be  acted  upon 
by  this  combination;  it  stim- 
ulates the  liver  and  the  intes- 
inal  glands;  increases  peris- 


taltic action  and  operates  thor- 
oughly without  griping  or 
causing  tenesmus.  As  a  remedy  in  habitual  constipation,  with 
torpid  liver  and  indigestion,  it  has  proved  very  efficacious  and 
its  continued  use  is  not  known  to  debilitate  the  bowels.  Dose : 
1  or  2  tablets  at  bedtime,  repeated  after  breakfast  and  dinner 
if  needed;  as  the  bowels  resume  their  normal  functions  the 
intervals  are  lengthened. 

Tablets  Cascara  Compound  No.  3,  Squibb 

Per  1000     Per  500     Per  100 
Chocolate-coated  (C.  C.  T.) 


Ext.  Cascara  Sagrada  1/2  gr. 
Aloin  1/g  gr. 

Podophyllin  l/io  gr. 

Oil    Peppermint  q.  s. 


Habitual  constipation  with 
hepatic  torpor  is  usually  cor- 
rected by  this  formula;  the 
activity  of  the  liver  is  in- 


creased by  the  action  of  the 
podophyllin,  while  all  parts  of  the  bowel  are  affected.  At 
times  griping  is  produced,  although  the  carminative  effect  of 
the  oil  of  peppermint  tends  to  correct  this.  In  many  cases  the 
addition  of  belladonna  is  an  improvement,  and  the  practitioner 
is  directed  to  these  various  combinations  under  their  several 
titles.  Dose :  1  or  two  tablets  at  bedtime,  repeated  after  break- 
fast if  necessary. 


The  prices  of  the  Squibb  Products  are  in  all  instances  as  low  as 
the  quality  and  quantity  of  ingredients  and  the  expense  of  man- 
ufacture allow.  They  include  containers,  packing  and  boxing.  When 
ordering  or  prescribing  medicinal  products,  specify  SQUIBB'S. 


346        SQUIBB'S  MATERIA  MEDICA 

Tablets  Cascara  Compound  No.  4,  Squibb 

(Anticonstipation) 

C.T.  Per  1000     Per  500     Per  100 

Chocolate-coated  (C.  C.  T.) 

Ext.  Cascara  Sagrada  1  gr.  1  Cascara  is  regarded  as  a  safe 
Ext.  Nux  Vomica  !/8  gr-  a°d  certain  laxative,  stimulat- 
Ext.  Belladonna  1/s  gr.  -  ing  the  intestinal  glands  and 

Ipecac  1/8  8r-         increasing  peristalsis.     Its  mild 

Podophyllin  */8  gr.  J       action  is  here  supplemented  by 

podophyllin,   an   active   chola- 

gogue  and  cathartic.  Ipecac  acts  as  a  gastric  and  hepatic  stimu- 
lant. Nux  vomica  and  belladonna  tend  to  prevent  griping,  to 
overcome  muscular  relaxation  of  the  bowel  and  to  render  the 
laxative  action  of  the  other  remedies  more  certain.  Headache, 
dyspeptic  symptoms  and  constipation  are  the  indications  for 
these  tablets.  Dose :  1  or  2  tablets  at  night. 

Tablets  Cascara  Sagrada  Extract  2  gr.,  Squibb 

Per  1000     Per  500     Per  100 
Chocolate-coated  (C.  C.  T.) 

These  tablets  represent  about  8  grains  of  carefully  selected  and 
well-cured  cascara  sagrada  bark.  They  have  been  found  useful 
in  the  treatment  of  habitual  constipation.  Dose:  1  tablet  after 
meals,  or  1  or  2  tablets  at  night;  decreasing  the  dose  or  taking 
less  frequently  as  the  constipation  is  relieved. 

Tablets  Cascara  Sagrada  Extract  3  gr.,  Squibb 

Per  1000     Per  500     Per  100 
Chocolate-coated  (C.  C.  T.) 

These  tablets  represent  about  12  grains  of  cascara  sagrada  bark. 
Dose:  1  tablet  after  meals  or  1  or  2  at  night. 

Tablets  Cascara  Sagrada  Extract  5  gr.,  Squibb 

Per  1000     Per  500     Per  100 
Chocolate-coated  (C.  C.  T.) 

These  tablets  are  equivalent  to  about  20  minims  of  fluidextract 
cascara  sagrada.  Dose :  1  tablet  after  dinner  or  at  bedtime. 

Tablets  Cascara  Fluidextract  5  min.,  Squibb 

C.T.  Per  1000     Per  500     Per  100 

Chocolate-coated  (C.  C.  T.) 

Cascara  sagrada  is  considered  a  safe  and  certain  Laxative,  stim- 
ulating the  intestinal  glands,  increasing  peristalsis,  and  acting  as 
a  tonic  to  the  intestinal  mucous  membrane.  Its  use,  it  is  main- 
tained, may  be  continued  as  long  as  occasion  arises,  without  en- 
feebling effect.  In  the  majority  of  cases  it  has  a  tendency  to 
act  in  decreasing  doses  and  to  gradually  restore  the  bowels  to 
their  normal  condition.  As  a  laxative  in  chronic  constipation 
it  is  deemed  one  of  the  best  remedies  thus  far  introduced.  Tab- 
lets Cascara  Fluidextract  Squibb  represent  the  active  properties 
of  5  grains  of  carefully  selected  and  well-seasoned  cascara 
sagrada  bark.  Dose :  1  or  2  tablets  at  night  or  after  meals, 
decreasing  as  the  constipation  is  relieved. 


SQUIBB'S  MATERIA  MEDICA        347 

Tablets  Cascarin  Compound,  Squibb 

Per  1000         Per  500         Per  100 

T.T. 

Chocolate-coated  (C.  C.  T.) 

Cascarin  1/4  gr.  "1       Where    a    decided    impression 

Aloin  1/4  gr.  |-      is     to     be     made     upon     the 

Podophyllin  1/4  gr.  J      bowels,       this      formula      has 

proved  very  satisfactory.  De- 
pending upon  the  dose,  it  acts  as  a  Laxative  or  Purgative.  It 
does  not  always  produce  griping,  but  where  constipation  is  pro- 
nounced and  the  fecal  accumulation  solid,  pain  is  sometimes 
produced.  This  may  in  a  measure  be  prevented  by  copious 
draughts  of  water,  and  is  not  so  liable  to  occur  under  the  con- 
tinued and  properly  regulated  use  of  the  tablets.  This  formula 
is  not  considered  eligible  where  an  inflammatory  condition 
of  the  intestines  exists.  Dose:  1  tablet  after  meals  with  water. 

Tablets  Cathartic.     See  Tablets  Aloin  and  Podophyllin  Com- 
pound. 

Tablets  Cathartic  Compound,  Squibb 

Per  1000       Per  500       Per  100 

C.  T. 

Chocolate-coated  (C.  C.  T.) 

Ext.  Coloc'th  Comp.     l*/4gr.  1       This  is  a  favorite  and   reput- 
Calomel  1  gr.  I       edly    very     efficient     formula. 

Ext.  Jalap  !/2  gr.  j       Its    action    is    directed    toward 

Gamboge  Powdered       1/4  gr.  J       all     parts     of     the     intestinal 

tract  and  the  organs  tribu- 
tary to  it.  Dose:  as  a  laxative,  1  tablet  at  night;  as  a  cathartic, 
2  or  more,  depending  upon  the  effect  desired. 

Tablets  Cathartic  Compound  Improved,  Squibb 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 


Ext.  Colocynth  Comp.       1  gr. 

Podophyllin  1/4  gr. 

Leptandnn  1/4  gr. 

Extract  Jalap  1/o  gr. 

Extract  Gentian  */o  gr. 

Ext.  Hyoscyamus  1/4  gr. 

Oil  Peppermint  q.  s. 


This  combination  of  vegetable 
extracts  and  resins  is  claimed 
by  some  practitioners  to  be 
more  satisfactory  in  its  action 
than  the  official  formula.  It 
is  offered  here  in  response  to 
a  demand,  and  is  made  from 


carefully  selected  drugs,  so 
that  its  merits  may  be  more  fully  determined.  Dose :  as  a  laxa- 
tive, 1  or  2  tablets  at  bedtime;  as  a  cathartic,  2  to  4  tablets. 


If  difficulty  is  experienced  in  procuring  any  Squibb  product, 
in  the  original  packages  here  listed,  please  notify  us;  we 
shall  see  that  your  wants  are  met  promptly  and  satisfactorily. 


348       SQUIBB'S  MATERIA  MEDICA 

Tablets  Cerium  Oxalate  1  gr.,  Squibb 

Per  1000          Per  500          Per  100 
C.T. 

Cerium  oxalate  acts  as  a  Gastric  Sedative.  It  is  used  to  allay 
nausea  and  vomiting  due  to  inflamed  conditions  of  the  mucous 
membranes,  and  to  control  reflex  vomiting  as  seen  in  seasickness 
and  in  pregnancy.  Dose:  for  adults,  1  to  5  tablets;  for  chil- 
dren, to  control  nausea,  1  tablet  every  half  hour  until  relieved. 

Tablets  Cerium  Oxalate  2  gr.,  Squibb 

C.T.  Per  1000  Per  500  Per  100 

Dose:  1  tablet  every  hour  for  four  or  five  doses  in  nausea  and 
seasickness;  for  vomiting  in  pregnancy,  I  to  3  tablets  three  or 
four  times  a  day. 

f  Tablets    Cerium    Oxalate    and    Cocaine    Compound, 
Squibb  (Nausea) 

C.T.  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 


Cerium  Oxalate  1  gr. 

Cocaine    Hydrochlor    ^40  gr 
Bismuth  Subnitrate  1  gr. 

Menthol  VlO  gr. 

Acid  Carbolic  1/io  gr. 

Tr.  Nux  Vomica          */2  min. 


This  formula  is  used  to  allay 
irritation  of  the  mucous  mem- 
brane, prevent  fermentation 
and  increase  tolerance  of 
food  in  nausea  due  to  gastric 
inflammation,  in  seasickness, 


vomiting     in     pregnancy,     etc. 

Dose:  2  tablets,  followed  by  1  tablet  every  hour  for  three  or 
four  doses.  In  the  use  of  these  tablets  the  possibility  of  the 
formation  of  the  cocaine  habit  should  be  remembered  and 
guarded  against. 

Tablets  Charcoal  5  gr.,  Squibb 

C.T.  Per  1000  Per  500  Per  100 

Charcoal  is  a  well-known  Absorbent  and  Antiseptic.  It  is  used 
in  dyspepsia  with  acid  eructations,  fermentation,  nausea  and 
vomiting;  checking  production  of  gas  in  the  stomach  and  bowels, 
and  relieving  the  various  unpleasant  symptoms  arising  therefrom. 
The  best  willow  charcoal  is  used  in  these  tablets,  and  they  will 
be  found  pleasant  to  the  taste;  they  may  be  eaten  or  swallowed 
with  a  little  water,  as  preferred.  Dose :  1  or  more  tablets  after 
meals,  or  oftener  if  required. 

Tablets  ChIoramine=T  4.6  gr.,  Squibb 

Per  1000         Per  500         Per  100 

Convenient  for  preparing  disinfectant  solutions  according  to  Dr. 
Dakin's  method.  1  tablet  dissolved  in  1  fluidounce  of  water 
makes  a  1  percent,  solution,  and  2  tablets  in  a  fluidounce  a  2 
percent,  solution;  these  are  the  ordinary  strengths  used  for 
wound  disinfection.  In  the  nose  and  throat  chloramine-T  is 
employed  in  j/^  per  cent,  solution,  obtained  by  dissolving  I 
tablet  in  4  fluidounces  of  water. 


SQUIBB'S  MATERIA  MEDICA        349 


f  Tablets  Chlorodyne,  Squibb 

C.T. 

Chocolate-coated  (C.  C.  T.) 


Per  1000       Per  500       Per  100 


Morphine  Hydrochlor.  1/g  gr. 
Extract  Cannabis  1/4  gr. 

Nitroglycerin  1/300  gr. 

Ext.  Hyoscyamus  !/2  gr. 

Oleoresin  Capsicum      l/io  gr. 
Oil  Peppermint          l/io  min. 


An  active  and  well  known 
combination  of  Antispas- 
modics  and  Anodynes  is 
presented  here.  It  is  used 
in  the  treatment  of  cramps, 
colic  and  diarrhea,  and  for 
the  relief  of  pain  generally. 
In  diarrhea  produced  by  change  of  drinking  water  or  by  ex- 
posure to  sudden  reduction  of  temperature,  with  severe  abdominal 
pains,  it  is  reported  to  afford  prompt  relief.  Dose :  1  tablet 
every  hour  if  necessary  for  pain;  discontinued  after  the  third 
dose  for  three  hours,  and  then  resumed  if  not  entirely  relieved. 
For  diarrhea,  I  tablet  every  three  hours  until  effective. 


f  Tablets  Chlorodyne  No.  2,  Squibb 

Per  1000 
C.T. 
Chocolate-coated  (C.  C.  T.) 

Morph.  Hydrochlor.     1/12  gr. 
Extract  Cannabis  */§  gr. 

Nitroglycerin 
Ext.  Hyoscyamus 
Oleoresin  Capsicum 
Oil  Peppermint 


Per  500       Per  100 


1/600 

V4  gr. 

a/20  gr. 

1/20  min.' 


Dose:     1 

for    three 
for    pain; 


every 


hour 


tablet 

doses  if  necessary 
discontinued  after 
the  third  dose  for  three 
hours,  then  resumed.  For 
diarrhea,  1  tablet  every  two 
or  three  hours  until  relieved. 


Tablets  Cholera  Infantum.      See     Tablets     Zinc     Sulpho- 
carbolate  and  Calomel  Compound. 

Tablets  Chromium  Sulphate  4  gr.,  Squibb 

Per  1000       Per  500       Per  100 
C.T. 
Chocolate-coated  (C.  C.  T.) 

Chromium  Sulphate  has  been  introduced  of  late  years  as  an 
Alterative  and  Nervine  for  use  chiefly  in  the  treatment  of  neuras- 
thenia, locomotor  ataxia  and  exophthalmic  goiter;  and  latterly 
it  has  also  been  proposed  as  a  remedy  in  hypertrophy  of  the 
prostate  gland.  The  reports  are  somewhat  conflicting,  but  in 
response  to  a  large  demand  we  have  added  the  tablets  to  our 
list.  Dose:  *  1  or  2  tablets  three  times  a  day  after  meals. 


The  Squibb  products  are  recognized  everywhere  as  the  Quality 
Standard.  They  are  of  uniform  purity  and  strength,  hence 
therapeutically  dependable.  When  ordering  or  prescribing  me- 
dicinal products,  you  will  do  well  always  to  specify  SQUIBB'S. 


350        SQUIBB'S  MATERIA  MEDICA 

f  Tablets  Cocaine  Hydrochloride  1%  8TM  Squibb 

(For  Solutions)  Per  100        Per  tube  of  25 

C.T. 

These  tablets  are  convenient  for  preparing  solutions  of  any 
strength:  1  tablet  dissolved  in  1  fluidrachm  of  water  yields 
approximately  a  two-percent,  solution;  dissolved  in  2  fluidrachms 
of  water  a  one-percent,  solution.  2  tablets  dissolved  in  I  fluid 
drachm  of  water  yield  a  four-percent,  solution,  etc.  Distilled 
or  sterile  water  should  always  be  used  in  preparing  solutions; 
and  if  for  hypodermic  use,  the  solution  should  be  passed 
through  absorbent  cotton.  Antidotes:  Chloral  hydrate;  amyl 
nitrite  by  inhalation;  caffeine  or  morphine;  stimulants. 

f  Tablets  Cocaine  Hydrochloride  2%  gr.,  Squibb 

(For  Solutions)  Per  100         Per  tube  of  25 

C.T. 

For  Preparing  Solutions:  1  tablet  dissolved  in  1  fluidrachm  of 
water  yields  approximately  a  four-percent,  solution. 

f  Tablets  Codeine  J^  gr.,  Squibb 

Per  1000  Per  500  Per  100 

T.T. 

Codeine  is  used  to  allay  pain,  relieve  restlessness  and  quiet 
cough;  its  action  being  that  of  a  mild  Anodyne  and  Sedative. 
The  indications  for  its  use  are  similar  to  those  for  morphine, 
but  it  is  said  to  cause  less  nausea  and  not  to  create  a  habit,  in 
view  of  which  it  is  employed  in  place  of  the  latter  where  pain 
is  not  too  pronounced  a  symptom.  Codeine  is  very  frequently 
used  in  diabetes,  to  check  the  inordinate  appetite,  reduce  the 
urinary  secretion  and  allay  the  thirst.  Dose :  1  tablet  three 
or  four  times  a  day  and  1  at  bedtime. 

f  Tablets  Codeine  54  Sr-»  Squibb 

Per  1000  Per  500  Per  100 

T.T. 

Dose:  1  tablet  every  three  or  four  hours,  as  a  mild  anodyne, 
to  allay  cough  and  to  relieve  symptoms  in  diabetes.  Used  also 
in  combating  the  opium  or  morphine  habit. 

f  Tablets  Codeine  ^  gr.,  Squibb 

Per  1 000  Per  500  Per  100 

T.T. 

Dose:  1  tablet  every  three  or  four  hours,  to  allay  pain  and 
restlessness,  to  relieve  the  cough  of  phthisis,  to  combat  the  opium 
habit  and  in  diabetes. 


SQUIBB'S  MATERIA  MEDICA       351 

f  Tablets  Codeine  and  Nickel  Compound,  Squibb 

(Anodyne  Infants',  Dr.  Waugh) 

Per  1000          Per  500  Per  100 

T.T. 


Codeine  Sulphate  !/67  gr- 

Nickel  Bromide  1/134  gr. 

Ipecac  1/134  gr- 

Lithium  Carbonate  */25  gr- 

Oil  Anise  Vl34  gr« 


These  tablets  are  used  to 
relieve  colic  and  allay  pain 
and  restlessness  in  very  young 
children.  Dose:  1  or  2  tab- 
lets, dissolved  in  a  little  hot 


water,   every   fifteen   to   thirty 
minutes  until  relief  is  obtained. 

7  Tablets  Codeine  Phosphate  %  gr.,  Squibb 

Per  1000          Per  500          Per  100 
T.T. 

Dose:  1  or  2  tablets  every  three  or  four  hours  as  a  mild  Ano- 
dyne, Cough  Reliever  and  Nerve  Sedative. 

f  Tablets  Codeine  Phosphate  y$  gr«»  Squibb 

Per  1000  Per  500  Per  100 

T.T. 

Codeine  phosphate  possesses  the  properties  of  the  alkaloid,  but  is 
a  very  soluble  salt,  and  probably  is  more  readily  absorbed. 
Dose :  1  tablet  every  three  or  four  hours. 

f  Tablets  Codeine  Phosphate  yz  gr.,  Squibb 

Per  1000  Per  500  Per  100 

T.T. 

Dose :    1   tablet  every  three  or  four  hours, 
f  Tablets  Codeine  Sulphate  %  gr.,  Squibb 

Per  1000  Per  500  Per  100 

T.T. 

Dose :  1  or  2  tablets  every  three  or  four  hours,  as  a  mild  Ano- 
dyne and  Sedative,  to  allay  cough,  quiet  restlessness,  and  to  con- 
trol the  unpleasant  symptoms  in  diabetes. 

f  Tablets.  Codeine  Sulphate  %  gr.,  Squibb 

Per  1000  Per  500  Per  100 

T.T. 

Dose  and  uses  as  of  Tablets  Codeine   (alkaloid)   1/4  gr. 
•f  Tablets  Codeine  Sulphate  yz  gr->  Squibb 

Per  1000  Per  500  Per  100 

T.T. 

Dose  and  indications  similar  to  those  of  Tablets  Codeine  (alka- 
loid) 1/2  gr. 


Since  we  make  only  one  quality  of  each  product,  that  best 
suited  to  the  purposes  intended,  the  specification  "Squibb's" 
is  not  open  to  various  interpretations,  but  has  a  plain,  positive 
meaning.  When  ordering  or  prescribing,  specify  SQUIBB'S. 


352       SQUIBB'S  MATERIA  MEDICA 
f  Tablets  Codeine  Sulphate  1  gr.,  Squibb 

T.T.  Per  1000  Per  500  Per  100 

Dose:  1  tablet  three  or  four  times  a  day  as  required,  as  an 
Anodyne  and  Soporific. 

Tablets  Colchicine  1/100  gr.,  Squibb 

T.T.  Per  1000          Per  500          Per  100 

Colchicine  is  largely  used  in  gout  and  rheumatism.  It  is  reported 
to  act  upon  the  nerves,  the  skin  and  the  bowels;  allaying  pain, 
inciting  free  perspiration  with  a  subsidence  of  the  fever  and 
inflammation,  and  producing  free  evacuations  from  the  bowels. 
Some  observers  state  that  it  acts  also  as  a  diuretic,  but  this  is 
denied  by  Garrod  and  others.  Certain  patients  show  more 
susceptibility  to  its  action  than  others,  and  it  is  hence  deemed 
best  to  begin  with  small  doses  and  gradually  increase  until  the 
systemic  effect  is  observed.  Dose:  1  tablet  every  three  hours 
until  bowels  move  or  symptoms  are  relieved. 

Tablets  Colchicine  1/50  gr.,  Squibb 

T.T.  Per  1000  Per  500  Per  100 

Dose:  1  tablet  three  times  a  day;  less  frequently  if  the  bowels 
move  too  freely.  In  overdoses  colchicine  is  an  active  poison. 

Tablets  Cold.      See     Tablets     Dover's     Powder     and     Aconite 
Comp. 

Tablets  Cold  No.  4.          See    Tablets    Aconite    and    Camphor 
Compound. 

Tablets  Cold  No.  5.       See     Tablets      Aconite      and      Calomel 
Compound. 

Tablets    Colic    No.    2,    Infantile.        See  Tablets  Sodium  Bi- 
carbonate Compound. 

Tablets  Compound  Licorice  Powder,  Squibb 

Put  up   in    1 -oz  packages  containing  22   tablets,    16  packages   to 

the  carton,  per  Ib. 

A  pleasant  and  efficient  laxative  confection  containing  the 
Squibb  special  compound  licorice  powder.  Dose :  1  or  2  tablets 
at  bedtime,  eaten  as  a  confection. 

Tablets  Copaiba  and  Salol.          See  Tablets  Salol  and  Co- 
paiba. 

*  Tablets  Copper  Arsenite  1/200  gr.,  Squibb 

T.T.  Per  1000  Per  500  Per  100 

Copper  arsenite  is  considered  a  valuable  remedy  in  acute  and 
chronic  diarrhea  in  children  or  adults  and  as  useful  also  in 
intestinal  indigestion  with  flatulence,  fermentation  and  disordered 
bowels.  Dose:  for  children,  I  tablet  every  three  or  four  hours 
until  diarrhea  is  checked;  for  adults,  1  tablet  every  two  or 
three  hours. 


SQUIBB'S  MATERIA  MEDICA        353 

*  Tablets  Copper  Arsenite  1/100  gr.,  Squibb 

T.T.  Per  1000  Per  500  Per  100 

Dose :  for  children,  1  tablet,  dissolved  in  half  a  glass  of  water 
and  a  teaspoonful  given  every  half  hour  until  the  symptoms 
improve;  adults,  a  tablespoonful  of  the  same  solution. 

Tablets  Copper  Sulphate  1  gr.,  Squibb 

C.T.  Per  1000  Per  500  Per  100 

These  tablets  are  made  from  pure  copper  sulphate  and  hence 
dissolve  completely  and  yield  clear  solutions  with  distilled 
water.  They  should  be  kept  well  stoppered  as  the  salt  is  very 
efflorescent.  They  are  employed  for  the  preparation  of  astrin- 
gent and  cicatrizant  solutions  for  use  on  sluggish  ulcerations, 
chancroids,  etc.  Directions:  Dissolve  2  to  4  tablets  in  a  fluid 
ounce  of  distilled  water. 

Tablets  Corrective.      See    Tablets    Strontium    Salicylate    and 
Charcoal  Compound. 

Tablets  Corrective,   Infants'.     See     Tablets     Calomel     and 
Bismuth  Compound. 

Tablets  Corrosive  Sublimate  1/100  gr.,  Squibb 

C.T.  Per  1000  Per  500  Per  100 

Dose :  in  diarrhea  and  dysentery,  1  tablet  every  hour  or  two 
until  the  discharges  change  in  character  or  are  controlled;  as 
an  Antiluetic  in  children,  1  tablet  after  each  meal. 

Tablets  Corrosive  Sublimate  1/60  gr.,  Squibb 

C.T.  Per  1000  Per  500  Per  100 

Dose :  in  diarrhea  and  dysentery,  1  tablet  every  hour  or  two 
until  the  character  of  the  discharges  changes;  as  an  Antiluetic, 
1  tablet  three  times  a  day. 

Tablets  Corrosive  Sublimate  1/50  gr.,  Squibb 

PerlOCO       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 

Dose:  as  an  Intestinal  Antiseptic,  1  tablet  every  two  hours;  as 
an  Antiluetic,  1  tablet  three  times  a  day. 

Tablets  Corrosive  Sublimate  1/30  gr.,  Squibb 

C.T.  Per  1 000  Per  500  Per  100 

Dose:  1  tablet  after  meals,  gradually  increased  until  systemic 
effect  is  observed,  in  syphilis  and  scrofula. 


The  founder  of  the  House  of  Squibb,  Dr.  Edward  R.  Squibb, 
not  only  had  high  ideals,  but  lived  and  labored  for  them;  and, 
in  the  words  of  William  Miller  Bartlett,  "the  House  of  Squibb 
stands  today  as  a  living  monument  to  the  honor,  integrity,  zeal 
and  devotion  of  its  founder." 

B 


354        SQUIBB'S  MATERIA  MEDICA 

Tablets  Corrosive  Sublimate  and  Ammonium  Chloride. 

See  Tablets  Mercury  Bichloride  Compound,  Wilson's. 

Tablets  Corrosive  Sublimate  and   Citric  Acid.          See 

Tablets  Mercury  Bichloride  Compound,  Bernays', 

Tablets  Coryza.      See    Tablets    Quinine    and    Camphor    Com- 
pound No.  3. 

Tablets  Coryza  No.  2.      See    Tablets    Quinine    and    Camphor 
Compound  No.  4. 

Tablets  Coryza  No.  3.      See    Tablets    Quinine    and    Camphor 
Compound. 

Tablets  Coryza  No.  5.      See    Tablets    Quinine    and    Camphor 
Compound  No.  2. 

Tablets    Coryza   Modified.      See   Tablets  Quinine,   Camphor 
and  Hyoscyamus  Compound. 

Tablets  Coryza  with  Heroin.       See     Tablets     Quinine     and 
Camphor  Compound  No.  5. 

Tablets  Cough,  Infants'.      See    Tablets    Ammonium    Chloride 
Compound  with  Heroin,  No.  2. 

Tablets  Cough,  Persistent.       See  Tablets  Ammonium  Chlo- 
ride and  Squill  Compound. 

Tablets  Cough,  Persistent,  with  Heroin.         See    Tablets 
Ammonium  Chloride  and  Squill  Compound  with  Heroin. 

Tablets  Cough    Sedative.       See  Tablets  Terpin  Hydrate  and 
Heroin  Compound. 

Tablets  Creosote  1  min.,  Squibb 

Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 

Creosote  has  been  used  with  good  results  in  chronic  bronchitis 
and  in  phthisis,  also  as  an  intestinal  antiseptic.  It  is  reported 
to  improve  nutrition,  increase  appetite,  diminish  expectoration 
and  cause  an  increase  in  weight.  It  is  recommended  to  give 
the  remedy  in  gradually  increasing  dose  until  the  point  of  toler- 
ance is  reached.  Should,  however,  gastric  disturbances  arise, 
its  use  is  discontinued  or  the  dose  reduced  until  the  irritation 
subsides.  Tablets  Creosote  Squibb  are  made  from  the  purest 
wood  creosote,  and  are  prepared  so  that  they  disintegrate  quickly 
in  the  stomach  and  cause  little  or  no  gastric  irritation.  Dose : 
1  tablet  immediately  after  meals,  with  water  or  milk,  gradually 
increased  as  tolerance  is  established. 

Tablets  Creosote  2  min.,  Squibb 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 

Dose:  1  or  more  tablets  after  meals;  in  chronic  bronchitis, 
phthisis,  tuberculous  diarrhea  and  as  an  intestinal  antiseptic 
generally. 


SQUIBB'S  MATERIA  MEDICA       355 

Tablets  Croup,  Spasmodic.      See      Tablets      Cannabis      and 
Hyoscyamus  Compound. 

Tablets  Cystitis.       See     Tablets     Acid     Boric     and     Buchu 
Compound. 

f  Tablets  Diacetylmorphine  1/24  gr.,  Squibb 

T.T.  Per  1000  Per  500  Per  100 

Diacetylmorphine  is  considered  a  remedy  of  much  value,  as  a 
stimulant  to  the  respiration  in  dyspnea  and  emphysema  and  as 
a  sedative  in  the  treatment  of  bronchial  and  tubercular  cough, 
and  to  be  preferable  to  morphine  as  a  cough  sedative  because 
it  does  not  disturb  digestion  readily.  In  asthma  its  action  is 
reported  to  be  prompt  and  prolonged,  not  only  diminishing  the 
severity  of  the  attacks,  but  preventing  their  recurrence.  Com- 
bined with  expectorants  it  is  deemed  useful  in  bronchitis,  pneu- 
monia and  grip,  and  it  is  also  used  as  a  mild  anodyne.  Accord- 
ing to  some  authorities,  diacetylmorphine  (or  heroin)  is  more 
toxic  than  morphine  and  less  valuable  for  the  relief  of  pain; 
it  is  equally  habit  forming.  Antidotes:  Same  as  of  morphine. 
Dose :  1  or  2  tablets  after  meals  and  at  bedtime,  for  the  relief 
of  cor.gh  and  pain. 

f  Tablets  Diacetylmorphine  1/12  gr.,  Squibb 

T  T.  Per  1000  Per  500  Per  100 

Dose :     1    tablet  after  meals  and  at  bedtime. 

f  Tablets  Diacetyimorphine   1/6  gr.,  Squibb 

T.T.  Per  1000  Per  500  Per  100 

Dose :    1   tablet  as  required,  cautiously  repeated. 

f  Tablets    Diacetylmorphine    Hydrochloride    1/24    gr., 
Squibb  Per  1000  Per  500  Per  100 

T.T. 

Dose :  1  or  2  tablets  after  meals  and  at  bedtime,  for  the  relief 
of  cough  and  pain. 

f  Tablets    Diacetylmorphine    Hydrochloride    1/12    gr., 
Squibb  Per  1000  Per  500  Per  100 

T.T. 

Dose :   1    tablet  after  meals  and  at  bedtime. 

f  Tablets     Diacetylmorphine     Hydrochloride     1/6     gr., 
Squibb  Per  1000  Per  500  Per  100 

T.T. 

Dose:     1    tablet  as  required,  cautiously  repeated. 


The  Squibb  Ideals  have  taken  concrete  form  in  the  Squibb 
Products;  these  are  universally  recognized  as  standards  of 
uniform  Purity  and  Efficacy,  that  is,  general  Excellence  and 
Reliability.  Specify  SQUIBB'S  when  prescribing  or  ordering. 


356       SQUIBB'S  MATERIA  MEDICA 

Tablets  Diarrhea      (Dr.  Sullivan).    See  Tablets  Opium,  Cam- 
phor and  Lead. 

Tablets  Diarrhea  No.  2.       See    Tablets    Calomel    and    Mor- 
phine Compound. 

Tablets  Diarrhea  Fermentative.       See      Tablets      Bismuth 
Subgallate  Compound  No.  3 

Tablets  Digestive.         See     Tablets     Pepsin     and     Pancreatin 
Compound  No.  3. 

Tablets  Digestive  Absorbent.       See    Tablets    Papain    and 
Charcoal  Compound. 

Tablets  Digestive  Aromatic.      See    Tablets    Pepsin,     Pan- 
creatin- and  Lactic  Acid  Compound. 

*  Tablets  Digitalin  (German)   1/100  gr.,  Squibb 

Per  1000  Per  500  Per  100 

T.T. 

According  to  authorities,  digitalin  is  a  direct  Cardiac  Stimulant 
and  Diuretic,  particularly  useful  in  cardiac  decompensation, 
where  the  heart  action  is  rapid  and  very  irregular  (auricular 
fibrillation).  Its  effects  are  produced  slowly,  but  they  are 
prolonged  and  cumulative,  especially  where  the  urinary  secre- 
tion is  not  increased.  The  direct  diuretic  action  of  digitalin 
is  stated  to  be  small,  and  the  drug  to  be  effective  in  dropsy 
only  when  the  latter  is  due  to  impaired  circulation.  Dose :  I 
tablet  every  three  or  four  hours. 

*  Tablets  Digitalin  (German)   1/60  gr.,  Squibb 

Per  1000  Per  500  Per  100 

T.T. 

Dose :  1  tablet  every  three  or  four  hours,  as  a  Renal  and  Cardiac 
Stimulant.  If  headache  or  digestive  disturbance  occur,  the  in- 
tervals between  the  doses  are  increased. 

Tablets  Digitalis  Fluidextract  1  min.,  Squibb 

Per  1000  Per  500  Per  100 

C.T. 

Digitalis  strengthens  heart  action.  It  increases  the  force  of  the 
contractions,  reduces  the  frequency  of  the  pulsations,  and  over- 
comes irregularity.  It  raises  arterial  tension  partly  by  increased 
muscular  contraction  of  the  heart,  but  chiefly,  according  to  Brun- 
ton,  by  contraction  of  the  artenoles.  It  is  used  as  a  Heart 
Stimulant  in  all  cases  of  weak,  irritable  or  intermittent  heart 
action.  The  direct  diuretic  action  of  digitalis  is  small,  but  ifS 
cardiac  disease  it  has  been  found  to  produce  marked  diuresis 
and  therefore  to  prove  of  value  as  a  rule  in  cardiac  dropsy. 
Dose :  I  tablet  three  or  four  times  a  day,  reducing  the  dose  if 
nausea,  flushing  of  the  face,  or  headache  occur. 


SQUIBB'S  MATERIA  MEDICA        357 

Tablets  Digitalis  and  Buchu  Compound,  Squibb 

(Diuretic) 

Per  1000       Per  500       Per  100 
C.T. 
Chocolate-coated  (C.  C.  T.) 

Digitalis  1  gr.  ]      These  tablets  are  employed  in 

Extract  Buchu  i  gr.  I      cardiac  and  renal  dropsy.      It 

Potassium  Nitrate  1  gr.  |      is     maintained     that     digitalis 

Squill  I  gr.  J       does    not    cause    any    stimula-' 

tion   of   the   epithelium   of   the 

kidney,  but  by  its  action  on  the  heart  in  disease,  it  causes 
diuresis  by  increasing  the  blood  supply  to  the  kidneys.  Squill 
has  been  found  useful  in  passive  forms  of  dropsy  where  the 
heart  is  obstructed  and  the  pulse  weak;  but  its  use  is  avoided 
when  an  irritable  condition  of  the  kidney  exists.  Buchu 
stimulates  the  mucous  membrane,  and  with  the  nitrate  of 
potassium  increases  the  diuretic  power  of  the  combination. 
Dose :  1  tablet  three  times  a  day,  between  meals,  with  a 
large  glass  of  water. 

Tablets  Digitalis  and  Cactus  Compound,  Squibb 

(Heart  Tonic  No.  2,   Dr.   Pultz) 

Per  1000       Per  500       Per  100 
T.  T. 
Chocolate-coated  (C.  C.  T.) 


Tr.  Digit.  U.S.P.'90  1  min. 
Tr.  Cactus  Grandifl.  1  min. 
Tr.  Stroph.  U.S.P.'90  1  min. 
Sparteine  Sulphate  VlCO  gr- 
Nitroglycerin  i/100  gr. 


Although  many  consider  the 
combination  of  a  number  of 
heart  remedies  unscientific, 
this  formula  enjoys  consider- 
able use  in  cases  of  weak, 


irregular  and  irritable  heart 
action.  Dose :  1  tablet  after  meals  or  of tener  if  required 
by  the  exigencies  of  the  case. 

Tablets  Digitalis  and  Calomel  Compound,  Squibb 

(Diuretic  No.  5) 
C.T.  Per  1000  Per  500  Per  100 


Digitalis  1/9  gr. 


Calomel  Vo  gr. 

Squill  !/2  gr. 

Caffeine  1/4  gr. 


Digitalis,    calomel    and     squill 


in  combination  are  recom- 
mended by  Ringer  and  other 
authorities  in  the  treatment  of 
renal  and  cardiac  dropsy, 
Caffeine  adds  additional  value  to  the  formula  by  its  stimulation 
of  the  secreting  structures  of  the  kidneys  and  by  increasing  the 
flow  of  blood  through  the  kidneys.  Dose  :  1  tablet  every  three 
or  four  hours  with  a  glassful  of  water. 


The  Squibb  Label  on  a  package  is  a  positive  guaranty  for  the 
uniform  Purity  and  Reliability  of  the  product.  We  make  only 
ONE  quality:  the  SQUIBB  quality;  and  our  prices  are  as  low 
as  they  can  be  made  for  that  quality.  Specify  SQUIBB'S. 


358       SQUIBB'S  MATERIA  MEDICA 

Tablets  Digitalis  and  Iron  Compound,  Squibb 

(Heart  Tonic,  Dr.  Gordinier) 

C.T.  P«rlOOO       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 

Fluidextract  Digitalis  1  min.  1  While  combining  several 
Iron  Reduced  I  gr.  I  heart  drugs  in  one  prescrip- 

Nitroglycerin  ^/200  gr-  r      hon   has   been   condemned   by 

Tr.  Stroph.  U.S.P/90  3  min.  I  many  practitioners,  these  tab- 
Strychnine  Sulph.  1/60  gr-  J  lets  enjoy  considerable  use  in 

functional  disturbance  as  well 

as  organic  disease  of  the  heart  accompanied  by  anemia.  They 
are  prescribed  as  long  as  improvement  continues;  should,  how- 
ever, flushing  of  the  face  or  nausea  or  headache  occur,  they 
are  discontinued  for  a  while.  Dose:  1  tablet  after  meals. 

Tablets  Digitalis  and  Strophanthus  Compound,  Squibb 

(Heart  Tonic  and  Stimulant,  Dr.  Da  Costa) 
T.T.  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 

Tr.  Digit.  U.S.P.'90  2  min.  "1  Though  objection  has  been 
Tr.  Stroph.  U.S.P.'90  2  min.  I  (made,  on  scientific  principles, 
Tr.  Bell.  U.S.P/90  */2  min.  f  to  combining  a  number  of 
Nitroglycerin  VlOO  gr.  J  heart  remedies,  these  tablets 

are    a    favorite     with     many 

physicians.  They  are  made  from  carefully  prepared  tinctures 
and  may  be  relied  upon  for  prompt  therapeutic  action.  Dose : 
as  a  cardiac  stimulant  in  collapse  and  angina,  1  or  2  tablets, 
repeated  as  necessary;  for  palpitation,  smoker's  heart  and  as 
a  cardiac  tonic,  1  tablet  every  three  or  four  hours. 

Tablets  Dinner.       See  Tablets  Aloes  and  Mastic. 

Tablets  Dipsomania.         See  Tablets  Gold  and  Sodium  Chlo- 
ride Compound. 

Tablets.  Diuretic.       See  Tablets  Digitalis  and  Buchu  Compound. 

Tablets   Diuretic  No.   5.       See  Tablets  Digitalis  and  Calomel 
Compound. 

f  Tablets  Dover's  Powder  5  gr.,  Squibb 

C.T.  Per  1000  Per  500  Per  100 

These  tablets  represent  5  grains  of  Squibb's  Ipecac  and  Opium 
Powder.  They  combine  convenience  with  accuracy  of  dose  and 
certainty  of  therapeutic  effect.  Dover's  powder  is  known  to 
relieve  pain  in  inflammatory  condilions  with  dry  skin  and  fever, 
where  no  nausea  exists,  and  has  hence  proved  an  excellent  rem- 
edy in  the  early  stage  of  a  cold,  taken  at  bedtime  and  its  dia- 
phoretic action  increased  by  a  hot  drink.  Dose :  1  tablet  every 
three  hours,  to  quiet  the  nerves,  and  2  tablets  at  bedtime,  with  a 
hot  drink,  in  the  early  stage  of  cold.  Used  also  in  diarrhea, 
generally  combined  with  small  doses  of  calomel. 


SQUIBB'S  MATERIA  MEDICA       359 

f*  Tablets  Dover's  Powder  2J^  gr.,  Squibb 

Per  1000       Per  500       Per  100 
T.T. 
Chocolate-coated  (C.  C.  T.) 

Opium  Powdered  */4  gr.  7      Each      of      these      tablets      is 

Ipecac  1/4  gr. j      equivalent    to    2*/2    grains    of 

Dover's      powder,      the     milk 

sugar  being  omitted  in  order  to  make  the  tablets  of  convenient 
size.  Dose:  for  children,  1  tablet;  for  adults,  1  tablet  every 
hour  in  sudden  cold,  for  four  doses,  or  4  tablets  in  one  dose. 

f  Tablets  Dover's  Powder  1  gr.,  Squibb 

Per  1000  Per  500  Per  100 

C.T. 

Opium  Powdered  VlO  gr.  \  Dose :  1  tablet  every  hour  in 
Ipecac  VlO  g*«  )  phthisis;  1  tablet  every  half 

hour    for   three   or    four   doses 
as  a  Diaphoretic  and  Nerve  Sedative  in  febrile  diseases. 

f  Tablets  Dover's  Powder  %  gr.,  Squibb 

Per  1000  Per  500  Per  100 

T.T. 

Dose:  1  tablet  every  hour  for  four  doses,  for  children;  as  a 
Sudorific  in  the  early  stage  of  a  cold. 

f  Tablets  Dover's  Powder  and  Aconite  Comp.,  Squibb 

(Cold,   Dr.   Gage) 

Per  1000       Per  500       Per  100 
C.T. 
Chocolate-coated  (C.  C.  T.) 


Dover's  Powder  2  gr. 

Tr.  Aconite  US.P.'90  1  min. 
Quinine  Sulphate  2  gr. 

Capsicum  l/4.gr. 


Small  doses  of  aconite  and 
Dover's  powder  reputedly  act 
very  well  together  in  the 


early  stage  of  colds;  inducing 
a  free  action  of  the  skin, 
relieving  muscular  pain  and  soreness,  allaying  cough,  quieting 
arterial  excitement  and  favorably  affecting  the  bronchial  secre- 
tions. Quinine  acts  as  an  antipyretic.  Capsicum  stimulates 
the  mucous  membrane  of  the  stomach  and  serves  to  cause  a 
more  rapid  absorption.  Dose:  1  tablet  every  three  or  four 
hours  until  the  fever  and  oppression  are  relieved.  Two  or  three 
tablets  at  bedtime  with  a  hot  drink  will  frequently  abort  a  coid. 


Squibb's  Tablets  are  made  from  the  Squibb  quality  of  ingredients 
and  by  improved  processes  that  insure  accurate  dosage  and 
rapid  and  complete  disintegration  or  solution  in  the  system, 
hence  prompt  and  full  therapeutic  effect.  Specify  SQUIBB'S. 


360       SQUIBB'S  MATERIA  MEDICA 

f  Tablets  Dover's  Powder  and  Belladonna  Compound, 
Squibb  (Bronchitis) 

T.  T.  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 

Dover's  Powder  VlO  gf  •  1       Bronchial   cough,  with   insuffi- 

Ext.  Belladonna  1/40  gr-  I      cient     secretion     and     painful 

Ipecac  1/20  gr.  |       and      difficult      expectoration, 

Quinine  Sulphate  */4  gr.  J       is  mentioned'  as  the  indication 

for  the  administration  of  these 

tablets.  Dose:  1  tablet  every  hour  for  four  or  five  doses,  then 
I  every  two  or  three  hours  until  relieved. 

Tablets  Dyspepsia,  Absorbent.       See  Tablets   Pepsin   and 
Charcoal  Compound. 

Tablets  Dyspeptic       (Dr.  E.  Haworth).    See  Tablets  Strych- 
nine and  Ipecac  Compound. 

Tablets  Dyspeptic  No.  2.      See  Tablets  Bismuth  and  Cascara. 

Tablets  Eisenzucker  3  gr.,  Squibb 

C.T.  Per  1000  Per  500  Per  100 

Eisenzucker  is  a  palatable  form  for  administering  iron  to  chil- 
dren and  delicate  women.  It  contains  about  3  percent,  metallic 
iron  in  the  form  of  saccharated  oxide.  It  is  readily  absorbed 
and  rarely  causes  any  constitutional  disturbance.  Squibb's 
Eisenzucker  Tablets  are  pleasant  to  the  taste,  and  may  be  eaten 
as  a  confection.  Dose:  1  to  3  tablets  after  meals. 

Tablets  Eisenzucker  5  gr.,  Squibb 

C.T.  Per  1000  Per  500  Per  100 

Dose:    1    to  2  tablets  after  meals. 

Tablets  Elaterin  1/10  gr.,  Squibb 

T.  T.  Per  1000  Per  500  Per  100 

So  many  demands  have.been  made  upon  us  for  a  reliable  prep- 
aration of  elaterium  that  we  have  decided  to  list  the  tablets 
of  the  active  principle.  These  are  employed  as  a  Hydragogue 
Cathartic  in  ascites,  as  well  as  in  the  dropsy  of  kidney  and  heart 
disease.  Their  administration  occasionally  causes  vomiting. 
Dose:  1  tablet  every  three  hours  for  not  more  than  three  doses 
in  succession. 

Tablets  Elaterin  %  gr.,  Squibb 

T.  T.  Per  1000  Per  500  Per  100 

Dose :  1  tablet  with  water,  cautiously  repeated  in  three  hours 
if  required. 

Tablets  Emmenagogue.        See  Tablets  Ergot  and  Manganese 
Compound. 

Tablets  Endometritis.          See   Tablets   Viburnum   Compound 
No.  2. 


SQUIBB'S  MATERIA  MEDICA       361 

Tablets  Epileptic.     See  Tablets  Triple  Bromides  and  Physo- 
stigma  Compound. 

Tablets  Ergot  and  Hydrastine,  Squibb 

(Uterine  Tonic) 

T.  T.  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 

Extract  Ergot  */4  gr-  }      Ergot  causes  a  contraction  of 

Hydrastine  1/100  gr. 1      'he       non-striated       muscular 

fibers,     acting     directly     upon 

the  muscular  coat  of  the  small  arteries  and  arresting  bleeding, 
hence  used  in  menorrhagia  and  metrorrhagia,  and  in  polypi  and 
fibroid  tumors.  Hydrastine  acts  as  an  astringent  and  tonic  to 
the  mucous  membranes,  and  also  causes  contraction  of  the  mus- 
cular tissue  of  the  vessels.  Dose:  1  or  2  tablets  three  or  four 
times  a  day. 

Tablets  Ergot  and  Manganese  Compound,  Squibb 

(Emmenagogue) 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 


Ext.  Ergot  !/2  gr- 

Manganese  Dioxide  */2  gr. 
Ext.  Cotton  Root  Bark  J/2  gr. 
Ext.  Black  Hellebore  1/2  gr. 
Iron  Sulphate  Dried  1/2  gr. 
Aloes  Purified  1/2  gr. 

Oil  Savine  1/s  min. 


This  combination  of  uterine 
remedies  is  reported  to  have 
proved  useful  in  ammenorrhea 
and  dysmenorrhea.  Dose:  1 
tablet  three  times  a  day  a 
week  before  the  expected 


period,  gradually  increasing 
to  I  tablet  every  two  or  three 
hours,  and  then  reducing  the  frequency  of  the  dose  as  the 
effect  is  produced.  It  is  advised  to  supplement  the  treatment 
with  hygienic  measures  and  generous  diet. 

*  Tablets  Euonymin  Compound,  Squibb 

(Hepatic,  Dr.  Kenyon) 

T.  T.  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 


Euonymin  */g  gr. 

Podophyllin  1/20  gr. 

Ipecac  1/8  §r- 

Calomel  1/g  gr. 

Aloin  1/12    r. 


These  tablets  are  employed  in 
that  condition  known  as  "bil- 
iousness," with  mental  hebe- 
tude, coated  tongue,  bad 
breath,  dyspeptic  symptoms 


and  constipation.  Dose: 
tablet  after  supper  and  1  at  bedtime;  or  1  or  2  at  night, 
followed  by  1  after  meals  every  second  day  until  the  conges- 
tion is  removed. 


This  house  supplies  only  one  quality  of  each  product:  that  best 
suited  to  the  purposes  intended.  The  specification  "Squibb's" 
is  not  open  to  various  interpretations;  it  has  a  plain,  posi- 
tive meaning.  Therefore,  when  prescribing,  specify  SQUIBB'S. 


362        SQUIBB'S  MATERIA  MEDICA 

Tablets  Expectorant,  Anodyne.        See  Tablets  Ammonium 
Chloride  and  Sanguinarine  Compound. 

Tablets  Extract  Cannabis.       See  Tablets  Cannabis  Extract. 

Tablets  Extract  Cascara.         See   Tablets    Cascara    Sagrada 
Extract. 

Tablets  Extract  Ergot  Y^  gr.    Squibb 

T.  T.  Per  1000     Per  500     Per  100 

Chocolate-coated  (C.  C.  T.) 

Squibb's  fluid  and  solid  extracts  of  ergot  have  been  the  reliance 
of  the  medical  profession  for  many  years.  Tablets  Extract 
Ergot  Squibb  represent  all  the  medicinal  virtues  of  the  best 
Spanish  Erg'ot  in  an  active  form.  If  kept  in  well-corked  bottles 
they  retain  their  therapeutic  properties  indefinitely.  Each  tablet 
represents  1 1/4  grains  of  Ergot.  Dose :  1  to  4  tablets  every  three 
or  four  hours,  to  control  internal  bleeding  and  as  a  nervine. 

Tablets  Extract  Ergot  1  gr.,  Squibb 

C.T.  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 

Each  tablet  represents  5  grains  of  the  best  Spanish  Ergot. 
Dose:  1  tablet  every  hour,  to  control  internal  hemorrhage;  1  to 
4  tablets  after  parturition,  to  contract  the  uterus  and  control 
bleeding. 

Tablets  Extract  Ergot  2  gr.,  Squibb 

C.T.  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 

Each  tablet  represents  10  grains  of  the  best  Spanish  Ergot. 
Dose :  1  tablet  every  two  or  three  hours,  to  cause  uterine  con- 
traction, to  control  hemorrhage,  in  the  treatment  of  fibroids  and 
as  a  nerve  tonic. 

Tablets  Extract  Nux  Vomica.       See   Tablets   Nux   Vomica 
Extract. 

Tablets   Fever  No.  2      (Dr.  Davis).    See  Tablets  Aconite  and 
Belladonna  Compound. 

Tablets  Fluidextract  Aconite.       See  Tablets  Aconite  Fluid- 
extract. 

Tablets  Fluidextract  Cascara.       See  Tablets  Cascara  Fluid- 
extract. 

Tablets  Fluidextract  Digitalis.      See  Tablets  Digitalis  Fluid- 
extract. 

Tablets  Follicular  Tonsillitis.     See    Tablets    Aconite    and 
Belladonna  Compound  No.  4. 


SQUIBB'S  MATERIA  MEDICA        363 

Tablets  Gargle  Astringent.       See    Tablets    Hydrastis    and 
Alum  Compound. 

Tablets  Gastritis.       See   Tablets  Silver   Nitrate   Compound. 

Tablets  Gentian  and  Nux  Compound,  Squibb 

(Anorexia) 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 


Ext.  Gentian  I  gr. 

Ext.    Nux   Vomica  Vio  gr- 

Ext.   Hydrastis  !/4  gr. 

Capsicum  1/10  gr- 


Ext.  Rhubarb  I  gr 

Ipecac  i/10  gr. 


Loss  of  appetite  depending 
upon  an  atonic  state  of  the 
digestive  organs  is  usually  cor- 
rected by  these  tablets.  They 


stimulate  the  salivary  glands 
and  the  gastric  mucous  mem- 
brane, increase  their  secretions, 
excite  peristalsis,  and  thus  aid  in  the  process  of  digestion.  Their 
action  being  also  slightly  laxative,  congestion  of  the  system 
is  relieved  and  H  normal  desire  for  food  created.  They  have 
been  found  useful  in  habitual  indigestion  with  loss  of  appetite, 
coated  tongue  and  constipation.  Dose :  1  or  2  tablets,  shortly 
before  meals,  repeated  in  an  hour  or  two  if  required. 

Tablets     Glycerophosphates     Calcium     and     Sodium, 
Squibb 
C.  t. 

Calcium  Glycerophosph.  1  gr.  ?  Clinical  observation  has  dem- 
Sodium  Glycerophosph.  1  gr.  {  onstrated  that  organic  diseases 

due    to    defective    metabolism, 

as  well  as  functional  disturbances  of  the  nervous  system,  are 
benefited  by  the  use  of  the  glycerophosphates,  the  administra- 
tion of  which  tends  to  cause  improvement  in  nutrition  of  the 
nerves  and  in  the  organic  functions,  and  to  stimulate  the  processes 
of  repair  by  their  effect  upon  oxidation  and  absorption.  They 
are  employed  in  all  cases  where  phosphorus  is  indicated;  in 
neurasthenia,  impaired  vitality  and  depressed  mental  states,  in 
wasting  diseases,  phosphatuna,  locomotor  ataxia,  functional 
impotence,  etc.  Dose :  1  to  3  tablets  after  meals  and  at  bed- 
time. 

Tablets  Glycerophosphates  Compound,  Squibb 

C.   T.  Per  1000  Per  500  Per  100 

Sodium  Glycerophosph.  1  gr.  T  The  addition  of  strychnine  to- 
Calcium  Glycerophosph.  2  gr  j-  the  glycerophosphates  of  so- 
Strychnine  Nitrate  1/64  gr.  j  dium  and  calcium  is  asserted 

to   increase    their   efficiency   in 

disorders  of  the  nervous  system  with  muscular  weakness  and 
functional  disturbance.  Dose :  1  or  2  tablets,  after  meals. 


The  prices  of  the  Squibb  Products  are  in  all  instances  as  low  as 
the  quality  and  quantity  of  ingredients  and  the  expense  of  man- 
ufacture allow.  They  include  containers,  packing  and  boxing.  When 
ordering  or  prescribing  medicinal  products,  specify  SQUIBB'S. 


364        SQUIBB'S  MATERIA  MEDICA 


Tablets   Glycerophosphates   Compound   No.  2,   Squibb 

(Dr.  Wm.  S.  Gordon) 
C.  T.  Per  1000  Per  500  Per  100 


Each  tablet  represents: 
Sodium  Glycerophosph.   1  gr. 
Calc.    Glycerophosph.      2  gr. 
Tr.  Nux  Vomica, 

U.S.P.'90,  71/2  min. 

Elix.    Gentian    Comp.    q.    s. 

ad  2  drs. 


This  combination  has  been 
used  with  asserted  good  re- 
sults in  the  weakened  and 
depressed  condition  of  the 
system  following  attacks  of 
grip,  in  neurasthenia,  melan- 
cholia, tuberculosis  and  loco- 


motor  ataxia.     Dose  :   1   or  2  tablets. 

Tablets  Gold  and  Sodium  Chloride  1/10  gr.,  Squibb 

C.  T.  Per  1000  Per  500  Per  100 

Gold  salts  are  prescribed  for  their  Nerve  Tonic  and  Altera- 
tive effects  in  exhausted  states  of  the  system  following  sexual 
excess  or  abuse  of  alcohol  or  tobacco;  in  anemia,  syphilis,  in 
diseases  of  the  kidney  with  malnutrition  and  albuminuria,  etc. 
Dose  :  1  tablet  after  meals  and  at  bedtime. 

Tablets  Gold  and  Sodium  Chloride  Compound,  Squibb 

(Dipsomania) 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 


Gold  and  Sod.  Chlor.  1/24  gr. 
Strychnine  Nitrate  1/<;o  gr. 
Nitroglycerin  V-iOO  gr- 

Atropine  Sulphate  1/«>oo  gr- 
Tr.  Digit.  US. P.  '90  3  min. 
Oleoresin  Capsicum  Vs  gr. 


Gold  and  sodium  chloride  as 
in  combination  with  the  heart 
and  nerve  tonics  in  this  for- 
mula, is  reported  to  have  given 
good  results  in  the  treatment 
of  the  alcohol  habit.  Dose: 
1  or  2  tablets  every  two  hours, 
increased  (cautiously)  if  necessary. 

Tablets  Guaiacol  1/2  gr.,  Squibb 

Per  1000        Per  500        Per  100 
Chocolate-coated  (C.  C.  T.) 

Guaiacol  was  introduced  into  the  materia  medica  by  Professor 
Mueller  as  being  superior  to  creosote.  Wood  creosote  owes  its 
therapeutic  value  largely  to  the  guaiacol  it  contains.  However, 
the  beneficial  effects  that  might  be  derived  from  the  use  of  guaia- 
col in  tuberculosis  are  often  not  obtained  on  account  of  its 
disagreeable  odor  and  taste  and  the  dyspeptic  symptoms  which 
its  administration  sometimes  causes.  These  objections  are  al- 
most entirely  overcome  in  Squibb's  tablets;  the  coating  covers 
the  taste  and  smell,  and  the  guaiacol  is  presented  to  the  stomach 
in  such  a  finely  divided  state  that  it  rarely  causes  any  digestive 
disturbance.  Dose  :  1  or  2  tablets  with  water  or  milk  every 
two  or  three  hours  or  thrice  daily. 


SQUIBB'S  MATERIA  MEDICA        365 

Tablets  Guaiacol  1  gr.,  Squibb 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 
Dose:     1    to  3   tablets  after  meals  and  at  bedtime,  with  water. 

Tablets  Guaiacol  Carbonate  1  gr.,  Squibb 

T.  T.  Per  1000  Per  500  Per  100 

Aside  from  its  recognized  therapeutical  value,  Guaiacol  Car- 
bonate owes  its  popularity  as  an  Intestinal  Antiseptic  and  Anti- 
tubercular  remedy  to  its  freedom  from  unpleasant  taste  or  odor 
and  the  absence  of  digestive  disturbances  or  other  bad  after- 
effects from  its  continued  use.  Dose:  1  to  5  tablets  three  or 
four  times  a  day,  with  water. 

Tablets  Halazone  1/16  gr.,  Squibb 

per   1,000          ;    per  500          ;   per   100 

Halazone  (Para-Sulphondichloraminobenzoic  Acid)  was  intro- 
duced by  Drs.  H.  D.  Dakin  and  E.  K.  Dunham  for  the  con- 
venient sterilization  of  drinking  water.  It  is  a  powerful  disin- 
fectant, acting  like  chlorine  but  having  the  advantage  of  being 
stable  in  solid  form.  The  tablets  contain,  besides  the  halazone, 
sufficient  anhydrous  sodium  carbonate  and  sodium  chloride  to 
render  them  quickly  soluble.  (Dr.  Dakin.)  For  use,  1  tablet 
is  added  to  a  quart  of  water,  and  the  latter  set  aside  for  about 
an  hour.  (Write  for  literature  on  Chloramine-T  and  other 
recent  chlorinated  products.) 

Tablets  Headache,  Neuralgic       (Dr.  Myers).     See  Tablets 
Acetanilid  and  Bromide  Compound. 

Tablets  Heart  Stimulant    (Dr.  Durant).     See  Tablets  Nitro- 
glycerin,  Digitalis  and  Strychnine. 

Tablets  Heart  Tonic     (Dr.   Gordinier).     See  Tablets  Digitalis 
and  Iron  Compound. 

Tablets    Heart    Tonic    No.    2    (Dr.    Pultz).      See    Tablets 
Digitalis  and  Cactus  Compound. 

Tablets  Heart  Tonic  and  Stimulant    (Dr.  Da  Costa).    See 
Tablets   Digitalis   and  Strophanthus   Compound. 


jf  difficulty  is  experienced  in  prpcuring  any  Squibb  product, 
in  the  original  packages  here  listed,  please  notify  us;  we 
shall  see  that  your  wants  are  met  promptly  and  satisfactorily. 


366        SQUIBB'S  MATERIA  MEDICA 


C.  T. 

Ext.    Helonias 

Ext.  Witch  Hazel 

Ext.  Hyoscyamus 

Fl.  Gold.  Seal  Colorl. 

Alum 

Acid  Tannic 

Acid  Boric 

Eucalyptol, 

Thymol, 

Menthol,  of  each 


Tablets  Helonias  and  Witch  Hazel  Compound,  Squibb 

(Leucorrhea) 

Per  1000  Per  500  Per  100 

1  gr.         These   tablets   act   as   an    As- 
1/2  gr-         tringent  and  Antiseptic.    They 
1  gr.         are  used  in  leucorrhea,  in  sub- 
1  min.         acute     gonorrhea     and     as     a 
I  gr.         prophylactic      of      contagion; 
1  gr.         either   as   a   douche   made   by 
8  gr.         dissolving   1    or  2  tablets  in  a 
pint  of  hot  water,  or  in  sub- 
stance inserted  into  the  vagina 
q.  s.  J       at  bedtime,  as  high  up  as  pos- 
sible,   and   allowed    to   remain 

over  night,  using  a  douche  of  at  least  a  quart  of  hot  water 
the  following  morning.  In  severe  cases  the  treatment  is  re- 
peated at  mid-day  and  the  douche  taken  before  retiring. 

Tablets  Hepatic   (Dr.  Kenyon).    See  Tablets  Euonymin  Comp. 
Tablets  Heroin.     See  Tablets  Diacetylmorphine. 

f  Tablets  Heroin  and  Digitalis  Compound,  Squibb 

(Cardiac  Asthma) 

T.  T.  Per  1000  Per  500  Per  100 

Fid.   Ext.  Digitalis        1  min.  "1      According  to  the  testimony  of 

Professor  Leo  and  other  com- 
petent  observers,  heroin  is  a 
good  remedy  for  asthma,  not 
only  exerting  a  decided  influ- 
ence over  the  paroxysms,  but  rendering  the  attacks  less  frequent. 
This  combination  is  reported  to  give  good  results  in  relieving 
dyspnea  and  emphysema  depending  upon  cardiac  or  pulmonary 
obstruction.  Dose:  1  or  2  tablets  every  two  or  three  hour's 
until  relieved. 

Tablets  Heroin  and  Terpin  Hydrate      See  Tablets  Terpin 
Hydrate  and  Heroin. 


.          . 
Diacetylmorphine 

(Heroin)  1/24  gr. 

Strychnine    Sulphate    !/48  gr- 


Tablets   Heroin   Hydrochloride. 

phine  Hydrochloride. 


See    Tablets    Diacetylmor- 


Tablets  Hexamethylenamine  5  gr.,  Squibb 

C.  T.  Per  1000  Per  500  Per  100 

Hexamethylenamine  has  be'en  used  to  render  the  urinary  secre- 
tion aseptic.  Its  action  depends  upon  the  fact  that  it  is  decom- 
posed in  the  system  into  formaldehyde,  which  being  largely  ex- 
creted by  the  kidneys,  has  the  effect,  it  is  claimed,  of  making 
the  urine  aseptic.  Advantage  is  taken  of  this  action  in  minor 
surgery  of  the  genito-urinary  organs,  the  remedy  being  admin- 
istered several  days  prior  to  the  intended  operation.  In  cystitis, 
with  alkaline  urine,  heavily  charged  with  pus  and  phosphates. 


SQUIBB'S  MATERIA  MEDICA        367 

Tablets   Hexamethylenamine  5   gr.,  Squibb   (Cont.) 

it  frequently  restores  the  acid  reaction  and  clears  the  urine.  Lat- 
terly die  simultaneous  use  of  sodium  acid  phosphate  has  been 
recommended  for  the  purpose  of  rendering  the  urine  acid  or  in- 
creasing its  acidity  and  thus  to  enhance  the  antiseptic  action  of 
the  hexamethylenamine  by  favoring  its  decomposition  and  the 
liberation  of  formaldehyde.  For  this  purpose  the  sodium  salt  is 
given  at  least  2  hours  before  the  hexamethylenamine.  In  sub- 
acute  gonorrhea,  pyelitis  and  catheter  fever,  good  effects  have 
also  been  observed  from  hexamethylenamine.  Occasionally  it 
causes  hematuria.  Dose :  1  or  2  tablets  every  three  or  four 
hours  and  at  bedtime,  with  a  large  glass  of  water. 


Tablets  Hexamethylenamine  7  1/2  gr.,  Squibb 

Per  1000  Per  500  Per  100 

C.  T. 

Dose :  1  or  2  tablets  every  three  or  four  hours,  and  at  bedtime,, 
with  a  large  glass  of  water. 

Tablets  Hydrastis  and  Alum  Compound,  Squibb 

(Gargle   Astringent) 

Per  1000     Per  500     Per  100 
C.T. 

Fl.  Golden  Seal  1       A  useful  gargle  in  relaxed  and 

(Colorless)  1  min.          inflamed      conditions      of      the 

Alum  3  gr.  !•      throat    may    be    readily    pre- 

Acid  Tannic  2  gr.  I       pared  with  these  tablets.  They 

Oil    Wintergreen  q.  s.  J       dissolve    quickly,    yielding    an 

Astringent  and  Antiseptic  fluid 

which  has  been  found  to  relieve  pain  and  ulceration  in  ton- 
sillitis and  pharyngitis.  Occasional  use  of  this  gargle  in  per- 
sons exposed  to  contagion  will  tend  to  keep  the  mucous  mem- 
brane of  the  mouth  and  throat  in  a  healthy  condition,  constring- 
iig  the  parts  and  restoring  the  tonicity  of  the  adjacent  muscles. 
In  loss  of  voice  from  strain  or  following  acute  throat  affec- 
tions, these  tablets  are  employed  with  benefit.  For  use,  1  or  2 
tablets  are  dissolved  in  a  glass  of  water  and  the  solution  used 
as  a  gargle  every  half  hour  or  hour,  warm  if  preferred.  [NoTE: 
These  tablets  do  not  yield  a  clear  aqueous  solution,  and  if 
such  is  desired,  the  liquid  should  be  strained  through  absorbent 
cotton.] 


The  Squibb  products  are  recognized  everywhere  as  the  Qualffy 
Standard.  They  are  of  uniform  purity  and  strength,  hence 
therapeutically  dependable.  When  ordering  or  prescribing  med- 
icinal products,  you  will  do  well  always  to  specify  SQUIBB'S. 


368       SQUIBB'S  MATERIA  MEDICA 

Tablets  Hydrastis  Compound,  Squibb 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 


Ext.  Hydrastis  1/4  gr. 

Ext.   Gentian  I  gr. 

Ext.   Taraxacum  1/2  gr. 

Ext.  Cascara  Sagrada  */2  gr. 

Ext.  Nux  Vomica  */8  gr- 

Capsicum  */8  gr. 

before  or  after  meals. 


Gastric  and  intestinal  atony 
are  said  to  be  relieved  by 
these  tablets.  They  have  been 
found  beneficial  in  atonic  dys- 
pepsia with  loss  of  appetite, 
slow  digestion,  and  disordered 
bowels.  Dose:  1  or  2  tablets 


*  Tablets      Hyoscine      (Scopolamine)      Hydrobromide 

1/200  gr.,  Squibb     Per  1000  Per  500  Per  100 

T.  T. 

According  to  clinical  observation,  hyoscine  acts  as  a  Sedative 
and  Hypnotic;  it  quiets  delirium,  induces  sleep  and  is  a  valu- 
able remedy  in  mania.  It  has  also  been  used  with  good  results 
in  sleeplessness  caused  by  worry  or  great  mental  activity.  Dose: 
I  tablet  every  hour  or  two  until  effective. 

*  Tablets  Hyoscine  Hydrobromide  1/100  gr.,  Squibb 

T.  T.  Per  1000  Per  500  Per  100 

Dose:  1  tablet  every  hour  until  relieved,  but  for  not  more 
than  three  doses. 

Tablets  Hysteria.     See  Tablets  Sumbul  Compound  No.  2. 

Tablets  Ignatia  and  Nux  Compound.        See  Tablets  Nux 
and  Ignatia  Compound. 

Tablets    Incontinence.   See    Tablets    Belladonna,    Nux    and 
Cubeb. 

Tablets  Infusion  Buchu  Compound.  See     Tablets     Buchu 
Compound. 

Tablets  Intestinal  Antiseptic.     See    Tablets    Zinc    Sulpho- 
carbolate  Compound. 

Tablets  Iodides,  Three.      See  Tablets  Three  Iodides. 

Tablets  Ipecac  and  Rhubarb  Compound.          See  Tablets 
Rhubarb  and  Ipecac  Compound. 

Tablets  Iron  and  Arsenic,  Squibb 

T.T.  Per  1000      Per  500      Per  100 

Chocolate'coated  (C.  C.  T.) 

Iron   Reduced  1  gr. )      This   combination   has   proved 

Acid  Arsenous  1/40  gr.  j      a  valuable  remedy  in  anemia; 

the  presence  of  the  arsenic  in- 
creases the  hematinic   effect  of  the   iron,   and   the  union  of   the 
•    two    remedies    often    accomplishes    results    that    could    not    be 
brought  about  by  either  agent  used   separately.      Particular  at- 
tention is  paid  to  the  careful  trituration  of  the  remedies,  so  that 


SQUIBB'S  MATERIA  MEDICA        369 
Tablets  Iron  and  Arsenic,  Squibb  (Cont.) 

uniform  and  accurate  dosage  is  obtained;  and  the  tablets  dis- 
integrate rapidly  in  the  system,  hence  prompt  therapeutic  results 
may  be  looked  for.  In  many  cases  the  addition  of  strychnine 
is  of-advantage,  and  such  tablet  combinations  are  offered  under 
the  title  of  Iron,  Arsenic  and  Strychnine.  Dose:  1  tablet  after 
meals,  with  water. 

Tablets  Iron  and  Arsenic  No.  2,  Squibb 

T.  T.  Per  1000       Per  500      Per  100 

Chocolate-coated  (C.  C.  T.) 

Iron  Reduced  1  gr  7      This  is  a  modification  of  the 

Acid  Arsenous  1/eo  gr.  )      foregoing  formula,  the  amount 

of    arsenous    acid    being    re- 
duced.    Dose:  1   tablet  three  or  four  times  a  day,  after  eating. 

*  Tablets  Iron,  Arsenic  and  Strychnine,  Squibb 

T.T.  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 

Iron  Reduced  1  gr.  1       These    tablets    are    used    with 

Acid  Arsenous  VlOO  gr.  r      good  results  as  a  tonic  in  de- 

Strycnine  Sulphate        VeO  gr-  J      bilitated  conditions  of  the  sys- 
tem,    with    loss    of    appetite, 

anemia  and  debility.  They  represent  three  of  the  best  systemic 
remedies,  reputed  to  improve  digestion  and  nutrition  and  over- 
come depraved  states  of  the  blood.  In  patients  where  consti- 
pation exists  an  occasional  dose  of  Tablets  Rhubarb  and  Ipe- 
cac Compound  No.  3  Squibb  is  recommended.  Dose :  1  tablet 
before  or  immediately  after  meals  and  at  bedtime,  with  water. 

*  Tablets  Iron,  Arsenic  and  Strychnine  No.  2,  Squibb 

T.T.  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 

Iron  Reduced  1  gr.  1       Dose :     1    tablet  before  or  mi- 

Acid    Arsenous  1/50  gr.  >•      mediately   after   meals   and   at 

Strychnine  Sulphate      1/60  gr-  J       bedtime,  with  water. 

Tablets  Iron,  Arsenic  and  Strychnine  No.  3,  Squibb 

T.T.  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 

Iron  Pyrophosphate  1  gr.  1  These  tablets  are  a  modifica- 
Acid  Arsenous  1/50  gr.  r  lion  of  our  Iron,  Arsenic  and 

Strychnine  Sulphate     VGO  ir-  J      Strychnine       formula,       pyro- 

phosphate   of  iron  being   used 

in  place  of  reduced  iron.  In  weak  and  impaired  digestion  the 
substitution  of  the  more  readily  assimilable  salt  is  an  advantage, 
supplying  an  added  element  of  nutrition — phosphorus.  Dose: 
1  tablet  before  or  after  meals  and  at  bedtime,  with  water. 


Since  we  make  only  one  quality  of  each  product,  that  best 
suited  to  the  purposes  intended,  the  specification  "Squibb's" 
is  not  open  to  various  interpretations,  but  has  a  plain,  positive 
meaning.  When  ordering  or  prescribing,  specify  SQUIBB'S. 


370        SQUIBB'S  MATERIA  MEDICA 

Tablets  Iron  and  Mercury.    See  Tablets  Mercury  and  Iron. 

Tablets  Iron  and  Strychnine  Compound,  Squibb 
(Dr.   Morrill) 

Per  1 000      Per  500      Per  100 
T.T. 
Chocolate-coated  (C.  C.  T.) 


The  alterative  and  tonic  effect 
of  iron,  arsenic  and  strychnine 
is  here  increased  by  small 
doses  of  quinine.  Anemic  and 


Iron  Reduced  */2  gr- 

Strychnine  Sulphate  1/i20  g>^ 
Quinine  Sulphate  !/2  8r- 
Acid  Arsenous  VlOO  8r- 

debilitated    conditions    due    to 

malarial  influences,  with  loss  of  appetite,  impaired  digestion,  and 
faulty  assimilation,  are  benefited  by  these  tablets,  and  in  chloro- 
sis and  anemic  amenorrhea,  as  well  as  in  neuralgic  affections 
depending  upon  defective  nutrition,  they  have  also  been  used 
with  good  results.  Dose :  1  or  2  tablets  with  water,  after  meals. 

Tablets  Iron  Peptonate  with  Manganese,  Squibb 

Per  1000  Per  500  Per  100 

Pink-coated  (P.  C.  T.) 


Iron    Peptonate  */4  8r- 

Manganese   Dioxide  1/10  §•"• 

Quinine  Sulphate  !/4  gr. 

Strych.    Phosphate  1/250  gr- 

Strontium    Arsenit*  1/250  §r- 


Use  is  made  in  these  tablets 
of  one  of  the  organic  salts  of 
iron,  which  is  claimed  to  be 
readily  absorbed  by  the  stom- 
ach without  disturbance,  and 


to  produce  a  rapid  and  perma- 
nent effect  upon  the  blood.  Strontium  arsenite  adds  an  altera- 
tive effect,  and  the  hematinic  action  of  the  iron  is  intensified 
by  the  manganese.  Strychnine  and  quinine  act  as  digestive 
and  systemic  tonics.  Dose  for  children:  I  tablet  after  meals. 

Tablets  Iron  Pyrophosphate  Compound,  Squibb 

C.T.  Per  1000         Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 

Iron  Pyrophosphate  I  gr.  "1       In    cases    of    lowered    vitality 

Quinine  Sulphate  */o  gr.  I       where    a    tonic    is    needed    to 

Strychnine  Sulphate  1/i;o  gr.  j  stimulate  metabolism,  this 
Acid  Arsenous  1/30  gr.  J  formula  .will  be  found  ser- 

viceable.     It  contains   four  of 

the  most  efficient  systemic  tonics,  and  favorable  results  may  be 
looked  for  in  anemia,  convalescence  from  disease,  cachexia,  and 
in  all  cases  where,  through  defective  metabolic  action,  the  con- 
dition of  the  system  is  below  normal.  Occasionally  in  some 
patients,  after  the  continued  use,  reddening  of  the  eyelids  and 
epigastric  pain  are  experienced,  due  to  the  arsenic.  If  these 
symptoms  arise,  it  is  advised  to  discontinue  the  tablets  for  a 
few  doses.  Dose:  I  tablet  with  water  after  meals  and  at 
bedtime. 


SQUIBB'S  MATERIA  MEDICA        371 

Tablets  Iron,  Quinine  and  Strychnine,  Squibb 

C.T.  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 

Iron  Reduced  1/2  gr.  "I       This     formula     is    universally 

Quinine  Sulphate  */2  gr.  V      recognized     as     an     excellent 

Strychnine  Sulphate    1/i20  gr-  J       tonic    in    all    debilitated    con- 
ditions;      loss      of      appetite, 

anemia  and  failing  strength  being  corrected  by  its  use.  It  is 
deemed  an  effective  combination  in  the  enfeebled  state  of  the 
system  following  acute  illness,  or  due  to  malarial  poisoning, 
poor  food  or  improper  surroundings.  Dose :  1  or  2  tablets 
after  meals,  with  water. 

Tablets  Iron,  Quinine  and  Strychnine  No.  2,  Squibb 

C.T.  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 

Iron  Reduced  1  gr.  1 

Quinine  Sulphate  1  gr.  j-      Dose :      1     tablet    after    meals 

Strychnine  Sulphate      I/go  gr.  J       and  at  bedtime,  with  water. 

Tablets  Laxative,  Children's    (Dr.  E.  Chapin).   See  Tablets 
Sodium  Phosphate  Compound. 

Tablets   Laxative  No.   5.       See  Tablets  Aloin  and  Strychnine 
Compound  No.  3. 

Tablets  Lead,  Opium  and  Camphor.     See  Tablets  Opium, 
Camphor  and  Lead. 

f  Tablets  Lead  and  Zinc  Compound,  Squibb 

(Astringent  Wash) 

C.T.  Per  1000  Per  500  Per  100 

Lead  Acetate  2  gr.  1       Dissolved      in      water,      these 

Zinc  Acetate  2  gr.  I       tablets     yield      an     astringent 

Berberine  Hydrochl.  1/20  gr-  f  an£l  sedative  lotion.  Ap- 
Morphine  Acetate  1/32  gr.  J  plied  to  indolent  sores  and 

ulcers     and      in      moist      skin 

diseases,  they  tend  to  allay  inflammation,  and  itching  and  to 
promote  healing.  As  an  injection  in  gonorrhea  and  leucorrhea 
they  have  also  given  excellent  results.  The  rapidity  with  which 
they  disintegrate  renders  them  very  convenient  for  preparing 
such  quantities  of  lotion  as  may  be  needed  without  delay.  They 
do  not  yield  a  clear  solution,  and  if  the  slight  precipitate  which 
is  present  is  objectionable,  it  may  be  removed  by  straining  the 
liquid  through  a  little  absorbent  cotton.  As  a  lotion  or  injection 
1  tablet  is  dissolved  in  2  to  4  fluidounces  of  water.  Keep  the 
bottle  well  corked,  and  dispense  in  glass. 


The  founder  of  the  House  of  Squibb,  Dr.  Edward  R.  Squibb, 
not  only  had  high  ideals,  but  lived  and  labored  for  them;  and, 
in  the  words  of  William  Miller  Bartlett,  "the  House  of  Squibb 
stands  today  as  a  living  monument  to  the  honor,  integrity,  zeal 
and  devotion  of  its  founder." 


372        SQUIBB'S  MATERIA  MEDICA 

Tablets    Leucorrhea.     See  Tablets  Helonias  and  Witch  Hazel 
Compound. 

Tablets  Licorice  and  Ammonium  Chloride.      See  Tablets 
Ammonium  Chloride  and  Licorice. 

Tablets  Licorice  Powder  Compound.      See    Tablets   Com- 
pound Licorice  Powder. 

Tablets  Lime  Water,  Squibb 

Per  1000  Per  500  Per  100 

C.T. 

These  tablets  are  offered  for  the  convenient  extemporaneous 
preparation  of  lime  water.  One  tablet  added  to  4  fluidounces 
of  water  in  a  clean  bottle  and  allowed  to  stand  until  it  dis- 
integrates, and  the  bottle  shaken  for  a  few  minutes  and  then 
placed  in  an  undisturbed  position  until  all  the  lime  subsides 
and  the  liquid  above  is  clear,  will  yield  a  solution  of  calcium 
hydrate  corresponding  in  strength  to  lime  water  of  the  U.S.  P. 
The  resultant  lime  water  may  be  decanted  from  the  precipitate 
as  wanted,  or  it  may  be  poured  off  into  a  clean  bottle,  which 
keep  well  corked. 

Tablets  Lithium  Effervescent  3  gr.,  Squibb 

Doz.  bots.  of  50         Per  1  000         Per  500         Per  1  00 
C.T. 

These  tablets  dissolve  with  rapid  effervescence  and  produce  a 
perfectly  clear  solution,  free  from  opacity  and  oily  appearance. 
Dose:  1  or  2  tablets,  dissolved  in  a  glass  of  water  and  taken 
an  hour  before  meals  and  at  bedtime. 

Tablets     Lithium     Effervescent   5  gr.,  Squibb 

Doz.  bots.  of  50         Per  1  000         Per  500         Per  1  00 
C.T. 

Dose:  1  or  2  tablets  dissolved  in  a  glass  of  water  three  or 
four  times  a  day,  an  hour  before  meals  and  at  bedtime. 

Tablets  Macrotin  Compound,  Squibb 

(Dr.  John  Stevens) 

Per  1000  Per  500  Per  100 

T.T. 


Macrotin  VlO  gr. 

Bryonia  */20  §r- 

Strychnine  Arsenate   Vl2.">  gr. 
Fl.  Ext.  Rhus  Tox.    i/L'O  m'n- 


This    formula  is    used    in    the 

treatment    of  rheumatic     and 

sciatic     pains.  Macrotin      is 

a       resinoid  derived       from 


black  cohosh,  and,  like  it, 
reputed  to  be  a  nervine  and  antispasmodic.  Bryonia  acts 
as  a  hydragogue  cathartic.  Strychnine  arsenate  is  used  in  rheu- 
matic and  neuralgic  pains,  often  of  obscure  malarial  origin. 
Poison  oak  acts  as  a  stimulant  narcotic  and  has  been  found 
useful  in  the  pains  of  chronic  rheumatism.  Dose  :  I  tablet 
every  2  hours;  in  severe  pain,  1  tablet  hourly  until  relieved. 


SQUIBB'S  MATERIA  MEDICA        373 

Tablets  Magnesia  Aromatic,  Squibb 

Perl 1000  Per  500  Per  100 

C.T. 

Each  of  these  tablets  represents  a  teaspoonful  of  milk  of  mag- 
nesia in  palatable  and  convenient  form.  They  contain  a  small 
quantity  of  aromatic!  to  overcome  the  flat  alkaline  taste  usually 
attending  the  liquid  preparation.  They  act  as  an  Antacid,  and 
in  large  doses  possess  also  Laxative  action.  Tablets  Magnesia 
Aromatic  Squibb  are  employed  for  correcting  acid  conditions  of 
the  mouth  as  well  as  gastric  hyperacidity;  and  they  may  be 
used  also  for  the  extemporaneous  preparation  of  milk  of  mag- 
nesia by  the  physician.  Dose:  1  or  more  tablets  as  occasion 
requires,  swallowed  with  a  little  water  or  diffused  in  a  spoonful 
of  water. 

Tablets  Magnesia  and  Sodium  Bicarbonate.        See  Tab- 
lets Sodium  Bicarbonate  and  Magnesia. 

Tablets  Magnesium  Oxide  Hydrated.       See  Tablets  Mag- 
nesia Aromatic. 


Tablets  Magnesium  Salicylate  5  gr.,  Squibb 

Per  1000  Per  500  Per  100 

C.T. 
With  Cacao 

The  physiological  action  of  magnesium  Salicylate  is  essentially 
the  same  as  that  of  sodium  salicylate,  but  it  has  latterly  been 
warmly  recommended  by  Prof.  I.  Boas,  of  Berlin  University, 
a  recognized  authority  on  gastroenteric  diseases  and  their  treat- 
ment, as  an  Antifermentative,  presenting  as  it  does  a  happy 
combination  of  the  antizymotic  salicylic  acid  and  just  sufficient 
of  the  laxative  magnesium  oxide  to  counteract  the  constipating 
and  consequently  the  cumulative  by-effect  of  the  acid.  Boas 
uses  it  in  flatulence  and  fermentative  dyspepsia  and  as  a  general 
Intestinal. Antiseptic.  Dose:  1  to  6  tablets  three  times  daily, 
with  water,  after  meals. 

Tablets  Manganese  and  Blaud's.       See    Tablets     Blaud's 
and   Manganese  Compound. 

Tablets  Manganese  and  Ergot.       See    Tablets    Ergot    and 
Manganese. 


The  Squibb  Ideals  have  taken  concrete  form  in  the  Squibb 
Products;  these  are  universally  recognized  as  standards  of 
uniform  Purity  and  Efficacy,  that  is,  general  Excellence  and 
Reliability.  Specify  SQUIbB'S  when  prescribing  or  ordering. 


374        SQUIBB'S  MATERIA  MEDICA 

Tablets  Manganese  Compound,  Squibb 

(Amenorrhea,  Anemic) 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 


Manganese  Dioxide  1  gr. 

Iron  Reduced  I  gr. 

Ext.  Gentian  1  gr. 

Ext.  Cascara  l/o  gr. 

Ext.  Nux  Vomica  Ve  gr- 

Capsicum  1/g  gr. 

Acid  Arsenous  ^50  gr. 


This  combination  of  tonics 
tends  to  reestablish  the  men- 
strual functions  when  their  ab- 
sence is  due  to  an  anemic  or 
cachectic  state  of  the  system, 
as  seen  in  poorly  nourished 
patients.  The  gentian  and 


nux   vomica   serve   to  increase 

the  appetite  and  improve  digestion.  The  iron,  arsenic  and 
manganese,  by  their  hematopoietic  action  tend  to  cause  a 
marked  improvement  in  nutrition.  Capsicum  acts  as  a  gastric 
stimulant;  cascara  removes  tissue  waste.  Dose:  1  tablet,  with 
water,  three  or  four  times  a  day. 

Tablets  Manganese  Dioxide  2  gr.,  Squibb 

Per  1000       Per  500       Per  100 
C.T. 
Chocolate-coated  (C.  C.  T.) 

Manganese  Dioxide  is  used  principally  for  its  Emmenagogue 
and  Hematinic  effects  in  amenorrhea  and  anemia.  It  acts  very 
much  like  iron,  and  usually  improves  nutrition,  as  shown  in  the 
increase  of  red  corpuscles  and  hemoglobin  in  the  blood,  and  in 
cases  of  amenorrhea  frequently  by  the  return  of  the  suspended 
function.  It  has  also  been  recommended,  in  larger  doses 
(10  grains  three  times  a  day),  in  gastrodynia  and  pyrosis. 
Dose:  1  or  2  tablets  three  times  a  day  after  meals,  with  water; 
in  amenorrhea  the  treatment  is  begun  four  or  five  days  before 
expected  period. 

Tablets  Mass  Blue  (Mercury)        See  Tablets  Blue  Mass. 

Tablets  Mercury  Bichloride.       See  Tablets  Corrosive  Subli- 
mate. 

Tablets  Mercury  Bichloride  Compound,  Bernays',  Large 
Squibb        (Antiseptic,  Bernays',  Large) 

Bots.  of  25        Per        Per        Per 
Per  doz.        1000       500        100 
T.  T.,  Blue  or  White 

Mercury  Bichloride  73/iogr.  1  For  external  use  only.  One 
Citric  Acid  34/sgr.  )  tablet  dissolved  in  a  pint  of 

water  yields  a  solution  con- 
taining one  part  of  corrosive  sublimate  in  one  thousand.  These 
tablets  are  poisonous  and  are  intended  only  for  preparing  anti- 
septic solutions.  They  should  be  kept  in  a  safe  place. 


SQUIBB'S  MATERIA  MEDICA        375 

Tablets     Mercury     Bichloride     Compound,     Bernays', 
Small,  Squibb  (Antiseptic  Bernays',  Small) 

Per  1000  Per  500  Per  100 
T.  T.,  Blue  or  White 

Mercury  Bichloride  !3/4gr.  1  The  addition  of  citric  acid 
Citric  Acid  87/100  gr-  )  to  mercury  bichloride  pre- 

vents     precipitation      of      the 

mercury  as  an  albuminate,  when  used  as  an  antiseptic  on  open 
wounds  or  mucous  surfaces.  The  tablets  offered  here  are  ex- 
tremely soluble  and  very  convenient  for  preparing  antiseptic 
solutions.  Dissolved  in  water  in  the  proportion  of  1  tablet  to  4 
fluidounces,  they  yield  a  perfectly  clear  solution  containing 
about  one  part  of  corrosive  sublimate  in  one  thousand.  These 
tablets  are  poisonous  and  should  be  kept  in  a  safe  place. 

Tablets  Mercury  Bichloride  Compound,  U.S.P.,  Squibb 

Coffin-shape,   Blue  or  White 

Bots.  of  25,  Per  doz.         Per  1 000         Per  500         Per  1 00 
Mercury  Bichloride  0.5  Gm.  )    Toxltabellcs  Hydrargyri  Chlor- 
Sodium  Chloride       0.5  Gm.  3   idl    Corrosivi.     Used    like    pre- 
ceding formula. 

Tablets  Mercury  Bichloride  Compound,  Wilson's 
Squibb  (Antiseptic,    Wilson's)  '• 

Bots.  of  25,  Per  doz.         Per  1 000         Per  500         Per  1 00 
C.  T.,  White  or  Blue,  or  Coffin-shape 

Mercury  Bichloride  73/io  gr.  j  These  tablets  are  intended 
Ammonium  Chlor.  77/iogr.  3  for  preparing  antiseptic  solu- 
tions. They  are  made  with- 
out the  addition  of  any  foreign  matter  and  yield  perfectly  clear 
solutions  with  distilled  water.  1  tablet  dissolved  in  a  pint  of 
water  makes  a  solution  of  about  1:1000.  When  "hard"  water 
(due  to  presence  of  lime  salts)  is  used  a  precipitate  is  occasion- 
ally produced.  Under  these  conditions  Tablets  Mercury  Bi- 
chloride Compound  Bernays'  may  be  used  to  advantage.  These 
tablets  are  now  furnished  coffin-shaped,  with  skull  and  cross- 
bones  and  stamped  "Poison." 

Tablets  Mercury  Iodide  Red  1/100  gr.,  Squibb 

Per  1000  Per  500  Per  100 

C.T. 

As  an  Alterative  and  Antiseptic  red  iodide  of  mercury  has 
proved  useful  in  diseases  of  the  blood  and  of  the  absorbent 
and  glandular  systems.  In  syphilis  and  scrofula  it  is  employed 


The  Squibb  Label  on  a  package  is  a  positive  guaranty  for  the 
uniform  Purity  and  Reliability  of  the  product.  We  make  only 
ONE  quality:  the  SQUIBB  quality;  and  our  prices  are  as  low 
as  they  can  be  made  for  that  quality.  Specify  SQUIBB'S. 


376       SQUIBB'S  MATERIA  MEDICA 
Tablets  Mercury  Iodide  Red  1/100  gr.,  Squibb  (Cont.) 

to  improve  nutrition  and  overcome  the  anemic  conditions;  as  a 
Cholagogue  in  disordered  states  of  the  liver;  and  as  an  Anti- 
septic in  some  forms  of  diarrhea.  In  tonsillitis  and  quinsy  it  has 
been  found  to  allay  the  inflammation  and  in  the  early  stages 
frequently  to  abort  an  attack.  Dose:  1  tablet  every  two  or 
three  hours. 

Tablets  Mercury  Iodide  Red  1/25  gr.,  Squibb 

T.T.  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.)  • 

Dose:    1  tablet  every  three  or  four  hours. 

Tablets  Mercury  Iodide  Red  1/16  gr.,  Squibb 

T.T.  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 

Dose:  in  hepatic  torpor,  1  tablet  every  three  hours;  in  con- 
stitutional treatment,  I  tablet  three  or  four  times  a  day. 

Tablets  Mercury  Iodide  Red  1/12  gr.,  Squibb 

T.T.  Per  1000       Per  500       Per  100 

Dose:     1  tablet  after  meals  and  at  bedtime,  as  an  Antiluetic. 

Tablets  Mercury  Iodide  Red  1/8  gr.,  Squibb 

Per  1000       Per  500       Per  100 

T.T. 

Chocolate-coated  (C  .C.  T.) 

Dose:  1  tablet  three  or  four  times  a  day,  for  constitutional 
treatment  in  syphilis. 

Tablets  Mercury  Iodide  Red  1/6  gr.,  Squibb 

Per  1000       Per  500       Per  100 
T.T. 

Dose:  1  tablet  three  or  four  times  a  day,  after  meals,  in  rather 
refractory  cases  of  syphilis. 

Tablets  Mercury  Iodide  Red  1/4  gr.,  Squibb 

Per  1000       Per  500       Per  100 
T.T. 

Dose :  1  tablet  three  or  four  times  daily,  in  obstinate  cases  of 
syphilis. 

Tablets  Mercury  Iodide  Yellow  1/50  gr.,  Squibb 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 

Yellow  iodide  (protiodide)  of  mercury  exhibits  the  same  con- 
stitutional effect  as  the  red  iodide,  but  its  action  is  less  severe. 
It  is  used  to  produce  mercurialization  with  little  systemic  dis- 
turbance. Dose :  1  tablet  every  two  hours  as  a  Cholagogue 
and  Intestinal  Antiseptic;  as  an  Antiluetic,  1  or  2  tablets  three 
or  four  times  daily,  after  meals. 


SQUIBB'S  MATERIA  MEDICA        377 

"Tablets  Mercury  Iodide  Yellow  1/25  gr.,  Squibb 

T.T.  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.)  « 

Dose :  1  tablet  every  two  or  three  hours  as  a  Hepatic  Stimu- 
lant and  Intestinal  Antiseptic. 

*Tablets  Mercury  Iodide  Yellow  1/8  gr.,  Squibb 

Per  1000       Per  500       Per  100 

T.T. 

Chocolate-coated  (C.  C.  T.) 

Dose :  1  to  2  tablets  every  2  or  3  hours  as  an  Antiluetic,  dimin- 
ishing the  dose  as  the  symptoms  ameliorate. 

"Tablets  Mercury  Iodide  Yellow  1/6  gr.,  Squibb 

T.T.  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 
Dose :  1    tablet  every  2  or  3  hours,  in  the  treatment  of  syphilis. 

"Tablets  Mercury  Iodide  Yellow  1/5  gr.,  Squibb 

Per  1000       Per  500       Per  100 
T.T. 

Chocolate-coated  (C.  C.  T.) 

Dose :  1  tablet  every  two  or  three  hours,  to  produce  mercuri- 
alization;  reduce  the  dose  as  the  effect  is  observed. 

"Tablets  Mercury  Iodide  Yellow  1/4  gr.,  Squibb 

Per  1000       Per  500       Per  100 

T.T. 

Chocolate-coated  (C.  C.  T.) 

Dose:  1  tablet  every  two  or  three  hours,  to  produce  the  con- 
stitutional effects  of  mercury. 

Tablets  Mercury  Iodide  Yellow  1/3  gr.,  Squibb 

Per  1000       Per  500       Her  100 

T.T. 

Chocolate-coated  (C.  C.  T.) 

Dose :  1  tablet  every  three  or  four  hours,  to  produce  the  con- 
stitutional effects  of  mercury,  the  dose  being  lessened  as  the 
symptoms  improve. 

Tablets  Mercury  Iodide  Yellow  1/2  gr.,  Squibb 

T.T.  Per  1000*      Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 

Dose :  1  tablet  every  three  or  four  hours  as  an  Antisyphilitic  in 
severe  cases,  the  dose  being  diminished  as  soon  as  the  con- 
stitutional effects  of  mercury  show  themselves. 

Squibb's  Tablets  are  made  from  the  Squibb  quality  of  ingredients, 
and  by  improved  processes  that  insure  accurate  dosage  and 
rapid  and  complete  disintegration  or  solution  in  the  system, 
hence  prompt  and  full  therapeutic  effect.  Specify  SQUIBB'S. 


378       SQUIBB'S  MATERIA  MEDICA 

Tablets  Mercury  Tannate  1/2  gr.,  Squibb 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 

Antisyphilitic;  not  affected  by  the  juices  of  the  stomach,  decom- 
posed in  the  intestinal  tract.  Dose:  1  tablet  every  two  hours; 
less  frequently  when  the  desired  effect  is  produced. 

Tablets  Mercury  Tannate  1  gr.,  Squibb 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 
Dose :    1   tablet  three  or  four  times  a  day. 

Tablets  Mercury  and  Iron,  Squibb 

(Ferruginous  Alterative) 

T.T.  Per  1000       Per  500       Per  100 

Merc.  Iodide  Yellow  1/4  8r<  \  The  administration  of  iron 
Reduced  Iron  1  gr.  j  with  mercurous  iodide  has 

been    found   useful    in    anemic 

and  cachectic  conditions  following  syphilis.  Dose :  1  or  2 
tablets  after  meals,  with  water. 

Tablets  Mercury  and  Potassium  Iodide.          See    Tablets 
Potassium  Iodide  and  Mercury. 

*Tablets  Mercury  with  Chalk  1/2  gr.,  Squibb 

Per  1000       Per  500       Per  100 
T.T. 

This  is  a  favorite  method  of  administering  mercury,  especially 
in  children's  practice.  It  is  used  in  congenital  forms  of  syphilis, 
and  as  a  hepatic  stimulant  to  correct  disturbances  of  digestion 
with  clay-colored  stools  and  constipation.  In  tonsillitis  in  chil- 
dren and  in  mumps  it  is  also  employed  with  great  benefit. 
Dose:  in  diarrhea,  1  tablet  every  two  hoars  until  relieved;,  in 
tonmlitis,  1  tablet  every  hour  until  symptoms  improve;  for 
constitutional  treatment,  1  tablet  three  or  four  times  a  day. 

*Tablets  Mercury  with  Chalk  1  gr.,  Squibb 

Per  1000       Per  500       Per  100 
T.T. 

Dose :  1  tablet  every  three  or  four  hours  for  adults,  as  a  Hepatic 
Stimulant  and  Alterative. 

Tablets   Migraine.      See  Tablets  Acetanilid  Compound. 

Tablets  Migraine  No.  2.     See   Tablets   Acetanilid   Compound 
No.  2. 

Tablets  Migraine  No.  3.    See   Tablets   Acetanilid   Compound 
No.  3. 

Tablets  Migraine  No.  4.    See   Tablets   Acetanilid   Compound 
No.  4. 


SQUIBB'S  MATERIA  MEDICA        379 


Tablets  Migraine  Improved. 

pound  Improved. 

Tablets  Milk,  Squibb 
C.T. 

Milk  Sugar  26  gr. 

Calcium  Lactophosph.  1/g  §r- 
Calcium  Carbonate  1  1/2  gr. 
Sodium  Bicarbonate  1/2  gr. 
Potassium  Bicarb.  1/12  gr. 
Sodium  Chloride  1/6  gr. 


See  Tablets  Acetanilid  Com- 
Per  250        Per  100 

These      tablets      supply      the 
necessary    salts    and    the   milk 


sugar  wanting  in  cow's  milk; 
and  experience  has  shown 
that  cow's  milk  modified  in 
this  way  makes  an  acceptable 
food  for  young  children.  In 
the  majority  of  cases  children  thrive  upon  the  milk  so  prepared 
Cleanliness  is  necessary  in  connection  with  the  nursing  bottles, 
nipples,  etc.  For  use,  1  tablet  is  crushed  and  added  to  each 
eight  ounces  of  milk,  the  number  being  increased  as  the  con- 
ditions warrant. 

Tablets  Milk  of  Bismuth.     See     Tablets     Bismuth      Oxide 
Hydrated. 

Tablets  Milk  of  Magnesia.       See  Tablets  Magnesia  Aromatic. 

Tablets  Mixed  Treatment        (Orthodox,  Dr.  Sherwell).     See 
Tablets   Potassium   Iodide   and   Mercury  Compound. 

fTablets  Morphine,  Camphor  and  Hyoscyamus,  Squibb 

(Anodyne) 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 


Morphine  Sulphate 

Camphor 

Extract  Hyoscyamus 

Oleoresin  Capsicum 


fiO  gr' 

1/S  gr. 

1/g  gr. 

1/60  gr. 


These  tablets  exert  a  Sedative 
and  Hypnotic  action  and  are 
used  for  the  relief  of  pain 
and  to  induce  sleep.  They 
should  not,  however,  be  given 
for  prolonged  periods  lest  there  be  danger  of  fastening  the 
morphine  habit  upon  the  patient.  They  are  considered  an  ex- 
cellent anodyne,  usually  affording  prompt  relief  in  sleepless 
and  restless,  conditions  accompanied"  by  pain.  Dose:  1  tablet 
every  half  hour  for  three  or  four  doses  until  relieved. 


fTablets  Morphine  Compound  No.  3,  Squibb 

T.T.  Per  1000  Per  500  Per  100 

Morphine  Sulphate          1/4  gr.  )       Anodyne,    Antispasmodic    and 
Atropine  Sulphate       Vl50  §r.  }       Hypnotic;          contra-indicated 

in      Bright's      disease.        The 

addition  of  atropine  lessens  nausea  and  depressing  effect.  Dose : 
1    tablet,   cautiously  repeated. 


This  house  supplies  only  one  quality  of  each  product:  that  best 
suited  to  the  purposes  intended.  The  specification  "Squibb's" 
is  not  open  to  various  interpretations;  it  has  a  plain,  posi- 
tive meaning.  Therefore,  when  prescribing,  specify  SQUIBB'S. 


380        SQUIBB'S  MATERIA  MEDICA 

f  Tablets     Morphine     and     Hyoscine     Hydrobromides 
Compound,  Squibb 

(Bromides  Compound,  Dr.  Hubbard) 

Per  1000  Per  500  Per  100 

T.  T. 

Morph.  Hydrobrom.  VlO  gr.  1  This  formula  is  an  Anodyne 
Hyoscine  Hydrobr.  1/200  8r-  f  Hypnotic,  and  has  been 
Camphor  Monobrom.  !/2  gr.  J  found  useful  in  nervous  con- 
ditions, with  pain  and  in- 
somnia, also  in  mild  cases  of  mania.  Dose ;  !  tablet  every  three 
or  four  hours,  cautiously  administered,  in  excited  states  of  the 
system  with  pain  which  prevents  the  patient  from  sleeping. 

fTablets  Morphine  Sulphate  1/16  gr.,  Squibb 

Per  1 000  Per  500  Per  100 

T.T. 

Dose:  1  or  2  tablets,  cautiously  repeated  every  three  or  four 
hours  for  pain.  Antidotes:  evacuation  of  the  .stomach  by 
means  of  an  emetic  or  by  the  stomach  pump  or  apomorphine 
hydrochloride  hypodermically ;  hot,  strong  coffee,  stimulants; 
cold  water  dashed  into  the  face;  keeping  the  patient  awake  by 
moving  him  about;  atropine  hypodermically,  and  the  galvanic 
current  if  required. 

t  Tablets  Morphine  Sulphate  %  gr.,  Squibb 

Per   1000         Per  500         Per   100 
T.T. 

Dose :     1   or  2  tablets,  cautiously  repeated  as  occasion  requires. 

f  Tablets  Morphine  Sulphate  1/6  gr.,  Squibb 

Per  1000         Per  500         Per  100 
T.T. 

Dose :    1    tablet,  cautiously  repeated   as  necessary. 

fTablets  Morphine  Sulphate   1/4  gr.,  Squibb 

Per  1000  Per  500  Per  100 

T.T. 
Dose :  1   tablet,  cautiously  repeated  as  may  be  required. 

fTablets  Morphine  Sulphate  1/2  gr.,  Squibb 

Per  1000  Per  500  Per  100 

T.T. 

Dose :  1    tablet,  cautiously  repeated  as  occasion  requires. 

fTablets   Morphine  Sulphate   1   gr.,  Squibb 

Per  1 000      Per  500       Per  100 
T.T. 

Dose:     1    tablet  only  as  needed,  and  cautiously  administered. 


SQUIBB'S  MATERIA  MEDICA        381 

Tablets  Naphthol  and  Bismuth  Compound,  Squibb 

C.T.  Per  1000  Per  500  Per  100 


Betanaphthol  3/s  gr. 

Bismuth  Subcarb.  22/s  gr. 

Salol  1  gr. 

Creosote  1  min. 

Oil  Cloves  q.  s. 


These   tablets  are   intended   to 
arrest   fermentation,   both   gas- 


tric and  intestinal.  They  are 
used  in  catarrhal  conditions 
with  flatulence,  pyrosis  and 
disordered  secretions,  and  in 
the  many  reflex  conditions  arising  from  delayed  or  imperfect 
digestion;  also  in  typhoid  and  tuberculous  diarrhea.  Betanaph- 
thol in  combination  with  bismuth  subcarbonate  acts  as  an  ener- 
getic antiseptic  and  sedative;  creosote  and  salol  aid  in  over- 
coming the  morbid  conditions  of  the  intestinal  canal;  and  oil 
of  cloves  helps  to  disguise  the  taste  of  the  creosote.  Dose :  in 
intestinal  indigestion,  1  tablet  before  meals,  repeated  two  hours 
afterwards  if  necessary;  in  tubercular  diarrhea  and  typhoid, 
1  or  2  tablets  every  two  or  three  hours,  depending  upon  the 
severity  of  the  symptoms. 

Tablets  Nausea.      See    Tablets   Cerium    Oxalate   and   Cocaine 
Compound. 

Tablets  Nausea  No.  2.      See    Tablets    Bismuth    and    Cerium 
Oxalate  Compound. 

Tablets  Nerve  Tonic  No.  5.      See    Tablets   Zinc    Phosphide, 
Cannabis  and  Nux. 

Tablets   Nervine.      See    Tablets    Camphor    and    Hyoscyamus 
Compound. 

Tablets  Neuralgic      (Dr.    Kenyon).      See   Tablets   Zinc    Phos- 
phide and  Cannabis  Compound. 

Tablets  Neuralgic   Brown=Sequard.       See  Tablets  Cannabis 
and  Aconite  Compound. 

Tablets  Neuralgic  Brown=Sequard,  Half  Strength 

See  Tablets  Cannabis  and  Aconite  Compound,   Half  Strength. 

Tablets  Neuralgic  Headache      (Dr.    Myers).      See    Tablets 
Acetanilid  and  Bromide  Compound. 

Tablets   Neuralgic   Improved.        See  Tablets  Acetanilid  and 
Cannabis   Compound. 

Tablets   Neutralizing.       See   Tablets    Rhubarb    and    Magnesia 
Compound. 

Tablets  Night  Sweat.       See  Tablets  Agaricin  Compound. 


The  prices  of  the  Squibb  Products  are  in  all  instances  as  low  as 
the  quality  and  quantity  of  ingredients  and  the  expense  of  man- 
ufacture allow.  They  include  containers,  packing  and  boxing.  When, 
ordering  or  prescribing  medicinal  products,  specify  SQUIBB  S. 


382        SQUIBB'S  MATERIA  MEDICA 

*Tablets  Nitroglycerin  1/200  gr.,  Squibb 

T.T.  Per  1000          Per  500 


Per  100 


Nitroglycerin  controls  spasm  and  paroxysmal  pain,  and  lessens 
arterial  tension  by  the  relaxation  which  it  produces  upon  the 
whole  arterial  system,  but  mainly  by  its  dilatation  of  the  arteri- 
oles.  It  thus  reduces  the  work  of  the  heart  and  under  its  influ- 
ence the  beat  becomes  full  and  regular.  It  is  deemed  a  valuable 
remedy  in  angina  pectoris,  syncope,  asthma,  epilepsy  and  the 
headaches  of  Bright's  disease,  and  it  is  employed  to  increase 
the  flow  of  urine  in  chronic  parenchymatous  nephritis.  If 
the  face  is  flushed  it  is  not  given.  Dose:  1  tablet,  repeated  in 
an  hour  if  necessary. 


*Tablets  Nitroglycerin  1/100  gr.,  Squibb 

Per  1000  Per  500 

T.T. 


Per  100 


Dose:     1    tablet,  repeated  in  an  hour  if  necessary.     Not  given 
if  the  face'  is  flushed. 


*TabIets     Nitroglycerin,     Digitalis     and     Strychnine, 
Squibb          (Heart  Stimulant,  Dr.  Durant) 

Per  1000       Per  500       Per  100 
T.T. 
Chocolate-coated  (C.  C.  T.) 

Nitroglycerin  VlOO  gr.  1      Dose :     1    tablet  three  or  four 

Fluidextract  Digitalis    1  min.  j-      times    a    day,    wherever    digi- 
Strychnine  Sulphate     i/SO  gr.  J       talis   appears    to    be    indicated 

in  chronic  valvular  disease. 


Tablets  Nux  and  Asafetida. 

Nux  Vomica. 


See    Tablets    Asafelida    and 


Tablets  Nux  and  Ignatia  Compound,  Squibb 

Per  1000       Per  500 
C.T. 
Chocolate-coated  (C.  C.  T.) 

Tr.  Nux  Vom.  US. P.  '90  1  min. 

Tr.  Ignatia 

Tr.  Cinchona 

Tr.  Matricaria 

Tr.  Gentian  Comp. 

Tr.  Calumba 

Phosphorus 


Per  100 


This  formula  has  proved 
serviceable  in  the  treatment 
of  atonic  dyspepsia.  The 
tablets  here  offered  are 
made  from  carefully  pre- 
pared tinctures  skilfully 
treated,  and  represent  the 

Aromatic  Powder  1  gr.  J  formula  in  its  original 

potency  minus  the  alcohol. 

Dose:  I    tablet  three  times  a  day,  before  meals,  with  a  swallow 

of  water. 


I  mm. 

5  min. 

1  min. 

1  min. 
1/2  min. 
1/300  gr. 
Igr-J 


SQUIBB'S  MATERIA  MEDICA        383 

Tablets  Nux  and  Ipecac  Compound,  Squibb 

(Bitter  Tonic,  Dr.  Frank  E.  West) 

Per  1000  Per  500  Per  100 

Chocolate-coated  (C.  C.  T.) 


Tr.  Nux  Vom.  US. P.  '90  5  min. 
Wine  Ipecac  1  min. 

Tr.  Capsicum  2  min. 

Tr.  Gentian  Comp.  5  min. 


Nux  vomica  stimulates  the 
functional  activity  of  the 
peptic  cells;  in  combina- 
tion with  ipecac,  capsicum 


and  gentian  this  'effect  is 
still  further  increased,  and  many  cases  of  digestive  and  intes- 
tinal torpor  are  corrected  by  their  administration.  This  formula 
has  been  found  useful  where  the  symptoms  of  coated  tongue, 
loss  of  appetite,  more  or  less  gastric  distress  and  headache  occur 
after  eating.  Dose :  1  tablet  before  meals,  with  water. 

Tablets  Nux  and  Pepsin,  Squibb 

(Dr.  Skiff)  Per  1000       Per  500       Per  100 

T.T. 

Nux  Vomica  VlOO  &•  }      Nux  vomica  and  pepsin  con- 

Pepsin  1/10  gr- )      stitute     a    useful     combination 

in     the     treatment     of     atonic 

dyspepsia.  The  dose  of  each  ingredient  being  small,  admits  of 
its  use  in  a  large  range  of  cases.  We  also  offer  this  combination 
in  a  more  concentrated  form.  (See  below.)  Dose:  1  tablet 
every  two  hours  or  2  tablets  after  meals,  repeated  as  needed. 

Tablets  Nux  and  Pepsin  No.  3,  Squibb 

T.T.  Per  1000  Per  500  Per  100 

Nux  Vomica  VlO  8r>  1      This     combination     stimulates 

Pepsin  1  gr.  j       the      gastric      secretions      and 

hastens  digestion.     It  has  been 

found  useful  in  atonic  dyspepsia.  On  account  of  the  small 
quantity  of  nux  vomica  in  the  formula,  the  tablets  may  be  given 
to  either  children  or  adults,  in.  appropriate  dosage.  Dose: 
1  or  more  tablets  after  meals,  repeated  in  an  hour  if  necessary. 

Tablets  Nux  and  Phosphorus  Compound,  Squibb 

(Aphrodisiac,  Dr.  Landers) 

Per  1000       Per  500       Per  100 
Chocolate=-coated  (C.  C.  T.) 

Extract  Nux  Vomica  */8  gr.  "I  This  formula  is  credited  with 
Phosphorus  VlOO  gr-  I  the  power  to  correct  lowered 

Extract  Damiana  V4  gr.  [       vitality  of  the   system   as   seen 

Gold  and  Sod.  Chlor.   I/go  gr.  J       in    debility,    neurasthenia    and 

sexual    exhaustion.      Dose :    1 
tablet  after  meals  and  at  bedtime. 


Jf  difficulty  is  experienced  in  procuring  any  Squibb  product, 
in  the  original  packages  here  listed,  please  notify  us;  we 
shall  see  that  your  wants  are  met  promptly  and  satisfactorily. 


384        SQUIBB'S  MATERIA  MEDICA 

Tablets  Nux  Vomica  Extract   1/4  gr.,  Squibb 

Per  1000       Per  500       Per  100 
T.T. 
Chocolate-coated  (C.  C.  T.) 

Nux  vomica  is  considered  a  valuable  remedy  in  atonic  dys- 
pepsia, stimulating  the  appetite,  overcoming  gastric  atony  and 
increasing  intestinal  peristalsis.  It  acts  as  a  tonic  upon  the  heart 
and  vasomotor  centers.  In  functional  paralysis,  neuralgia,  im- 
potence, incontinence  of  urine,  and  as  a  general  nerve  tonic  it 
has  also  been  used  with  good  results.  The  tablets  offered  here 
are  made  from  an  assayed  extract;  and  the  alkaloidal  content 
being  always  the  same,  uniform  and  reliable  therapeutic  effects 
may  confidently  be  expected.  Dose:  I  tablet  after  meals. 

Tablets  Occult  Blood  Test,  Squibb 

per  package  containing  5  x  20  tablets  and  a  dropping  bottle  of 

glacial  acetic  acid, 

It  is  essential  that  any  test  for  occult  blood  be  accurate,  and 
important  that  it  be  simple  in  its  technic.  After  considerable 
experimenting,  Dr.  Dudley  Roberts,  of  Brooklyn,  N.  Y., 
worked  out  an  extremely  satisfactory  benzidin  tablet,  and  in 
both  private  and  hospital  work  he  has  come  to  use  it  to  the 
exclusion  of  other  tests.  This  tablet  is  composed  of  1  part 
benzidin  to  20  parts  of  sodium  perborate  triturated  with  great 
care  and  made  up  into  a  5-grain  tablet.  The  specimen  to  be 
tested,  either  a  weak  emulsion  of  the  stool  or  the  stomach  con- 
tents or  urine,  is  placed  either  in  a  small  saucer,  pus  basin  or 
porcelain  dish  in  sufficient  quantity  to  wet  the  tablet  thoroughly, 
but  not  to  entirely  immerse  it.  A  drop  or  two  of  glacial  acetic 
acid  on  the  tablet  if  blood  be  present  gives  rise  to  a  more  or 
less  immediate  change  in  the  tablet  to  a  greenish  blue.  Experi- 
ence with  its  use  gives  a  fairly  accurate  idea  of  the  amount  of 
occult  blood  present,  depending  on  the  extent  and  quickness  of 
the  color  change.  If  the  amount  of  blood  is  small,  only  the 
edge  of  the  tablet  may  turn.  Such  is  th«  simplicity  of  this 
tablet  test  for  occult  blood  that  a  nurse  or  intelligent  patient 
may  watch  t-he  appearance  or  disappearance  of  occult  blood 
without  laboratory  apparatus  of  any  kind,  with  merely  a  small 
dish  and  the  handle  of  a  spoon  with  which  to  make  a  thin 
emulsion. 

f  Tablets  Opium    (Powdered)  1/4  gr.,  Squibb 

Per  1000  Per  500  Per  100 

T.T. 

Hypnotic,  Sedative  and  Anodyne.  These  tablets  are  made 
from  Squibb's  powdered  opium,  and  contain  all  of  its  properties 
in  an  unaltered  form.  Dose:  1  to  4  tablets  repeated  as  required. 

f  Tablets  Opium     (Powdered)  1/2  gr.,  Squibb 

T.T.  Per  1000  Per  500  Per  100 

Dose :      1   or  2  tablets,  repeated  as  required. 


SQUIBB'S  MATERIA  MEDICA        385 

•{•Tablets  Opium  and  Camphor,  Squibb 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 

Opium  Powdered  i/4  gr.  \      Anodyne,   Antispasmodic    and 

Camphor  */4  gr.  j      Intestinal   Astringent.      Opium 

and      camphor      represent      a 

favorite  combination  for  the  relief  of  pains  of  a  spasmodic 
character;  also  used  in  diarrhea  accompanied  by  cramps.  The 
tablets  are  supplied  coated  only  to  prevent  loss  of  camphor  by 
volatilization.  Dose :  1  or  2  tablets  every  3  or  4  hours. 

fTablets  Opium  and  Camphor  Compound,  Squibb 

(Sun  Cholera) 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 

Tincture  Opium  ]       It    will     be     noted     that     this 

Spirit  Camphor  formula       is       equivalent       to 

Tincture  Rhubarb  1 5     minims     of     the     mixture, 

Tincture  Capsicum  publicly  exploited  as   the  Sun 

Spirit  Peppermint   aa   3  mm.  J       cholera       mixture.         Sudden 

attacks  of  cramps  and  diar- 
rhea are  usually  relieved  by  these  tablets.  They  represent  the 
full  therapeutical  activity  of  the  formula  in  a  convenient  and 
permanent  form.  In  chronic  diarrhea,  Tablets  Zinc  Sulpho- 
carbolate  Compound  Squibb  are  considered  more  useful.  Dose: 
2  tablets,  with  water,  followed  by  1  tablet  after  each  loose 
movement  until  relieved. 

fTablets  Opium,   Camphor  and   Lead,  Squibb 

(Diarrhea,  Dr.  Sullivan) 

Per  1000       Per  500       Per  100 
C.  T. 
Chocolate-coated  (C.  C.  T.) 

Opium  Powdered  */4  gr.  1       Lead  acetate  acts  as  an  intes- 

Camphor  1/4  gr.  1       tinal    astringent,   opium    as    an 

Lead  Acetate  !/6  8r-  f      antiperistaltic;    in    colliquative 

Ipecac  !/8  gr.  J       diarrhea,    camphor    serves    to 

check     vomiting,     to     prevent 

cramps,  and,  by  its  stimulating  effect  upon  the  circulation,  to 
restore  warmth  to  the  extremities;  ipecac  tends  to  quiet  the 
stomach  if  nausea  exists  and  to  increase  the  activity  of  the 
liver.  Dose :  2  tablets,  followed  by  1  tablet  every  hour  for 
five  or  six  doses;  then  1  tablet  after  each  loose  movement. 


The  Squibb  products  are  recognized  everywhere  as  the  Quality 
Standard.  They  are  of  uniform  purity  and  strength,  hence 
therapeutically  dependable.  When  ordering  or  prescribing  med- 
icinal products,  you  will  do  well  always  to  specify  SQUIBB'S. 


386       SQUIBB'S  MATERIA  MEDICA 

Tablets  Orthodox.    See  Tablets  Potassium  Iodide  and  Mercury 
Compound. 

Tablets  Oxgall  Compound,  Squibb 

(Dr.  Wm.   H.   Porter) 

Per  "1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 


Oxgall  Purified  1  gr. 

Pancreatin  1  gr. 

Ext.  Colocynth  Comp.  */4  gr. 

Quinine  Hydrochlor.  !/2  gr. 

Ext.  Nux  Vomica  1/g  gr. 

Ext.  Taraxacum  1  gr. 


Oxgall  favors  the  assimila- 
tion of  fats,  tends'  to  prevent 
intestinal  fermentation,  in- 
creases the  peristaltic  action 
of  the  bowels  and  hence  acts 
laxative;  pancreatin 


assists  in  the  digestion  of 
fatty  and  starchy  food  and  improves  nutrition;  quinine  and  nux 
vomica  remove  the  atonic  conditions;  extract  of  colocynth  com- 
pound and  taraxacum  stimulate  the  liver  and  overcome  hepatic 
torpor.  The  combination  is  a  favorite  remedy  in  intestinal 
indigestion  in  women  and  persons  of  sedentary  habits,  acting 
remarkably  well  in  neurasthenic  patients.  Dose:  1  or  2  tablets 
before  meals,  repeated  in  two  hours  if  required. 

Tablets  Papain  and  Charcoal  Compound,  Squibb 

(Absorbent  Digestive) 

Per  1000  Per  500  Per  100 

C.T. 


Papain  1  gr. 

Charcoal  2  gr. 

Sodium  Bicarbonate  2  gr . 

Ext.  Nux  Vomica  VlO  gr. 

Ipecac  !/io  gr. 

Wintergreen  Flavor  q.  s. 


Antacid,  Corrective,  Digest- 
ive. Papain  is  a  digestive 
ferment,  and  is  active  in 
alkaline  as  well  as  acid  secre- 
tions. In  combination  with 
charcoal  and  sodium  bicar- 


bonate it  has  been  found 
useful  in  delayed  digestion,  accompanied  with  fermentation, 
flatulence  and  pyrosis.  Ipecac  and  nux  vomica  stimulate  the 
peptic  cells  and  hence  overcome  gastric  atony.  Tablets  Papam 
and  Charcoal  Compound  are  used  with  generally  good  results 
in  chronic  indigestion,  in  acute  indigestion  the  result  of  over- 
eating or  imperfect  mastication  of  food,  or  where,  from  de- 
bilitated conditions,  the  secretion  of  gastric  juice  is  deficient  in 
amount  or  weak  in  digestive  power.  Dose :  ordinarily  1  or  2 
tablets  are  given  immediately  before  meals  or  after  each  meal, 
with  water,  and  repeated  in  an  hour  or  two  if  required;  some- 
times, however,  4  to  6  tablets  are  administered  for  one  dose, 
with  a  glass  of  moderately  hot  water,  for  the  relief  of  acute 
dyspepsia.  It  is  maintained  that  the  use  of  these  tablets  may 
be  continued  for  prolonged  periods  without  thereby  weakening 
the  digestive  functions. 


SQUIBB'S  MATERIA  MEDICA       387 

Tablets  Papain  Compound,  Squibb 

Per  1000  Per  500  Per  100 

C.T. 

Papain  3/4  gr,  ~|       This   is   considered    an   excel- 

Charcoal  3/4  gr.  !       lent  combination,  agreeable  to 

Sodium  Bicarbonate  2  gr.  [  the  taste  and  usually  afford- 
Wintergreen  Flavor  q.  s.  J  ing  prompt  relief  in  gastric 

indigestion,    by    virtue    of    its 

Antacid,  Digestive  and  Corrective  properties.  It  has  been  added 
to  our  list  in  response  to  repeated  demands  from  physicians  and 
to  take  the  place  of  a  popular  proprietary  remedy.  Dose :  1  to 
3  tablets  after  meals,  repeated  in  an  hour  or  two,  if  required. 

f  *  Tablets  Paregoric  10  min.,  Squibb 

Per  1000  Per  500  Per  100 

T.T. 

Opium  Powdered  !/25  gr- 1  Each  tablet  is  equivalent  to 
Camphor  1/05  gr.  I  10  minims  of  Tinctura  Opii 

Acid  Benzoic  */25  gr.  f      Camphorata    U.    S.    P.    IXth 

Oil  Anise  1/35  gr.  J       Rev.     Useful  as  a  mild  Ano- 

dyne   in    relieving    pain    and 

colic,  and  in  allaying  restless  conditions  in  young  children. 
The  effect  is  more  promptly  produced  if  the  tablets  are  given 
in  hot  water.  Dose:  1  to  6  tablets  according  to  the  age. 

Tablets  Pepsin  1  gr.,  Squibb 

Per  1000  Per  500  Per  100 

T.T. 

The  pepsin  here  used  has  a  digestive  strength  of  1  to  3000. 
These  tablets  are  indicated  where  gastric  secretion  is  scanty  or 
weak  in  digestive  strength.  Dose :  1  or  2  tablets  after  meals. 

Tablets  Pepsin  3  gr.,  Squibb 

Per  1000  Per  500  Per  100 

C.T. 
Dose:     1    tablet  after  eating,   repeated  in  an  hour  if  necessary. 

Tablets  Pepsin  5  gr.,  Squibb 

Per  1000  Per  500  Per  100 

C.T. 
Dose :     1    tablet   after  meals,   repeated   in  an  hour  if   necessary. 


Since  we  make  only  one  quality  of  each  product,  that  best 
suited  to  the  purposes  intended,  the  specification  "Squibb's" 
is  not  open  to  various  interpretations,  but  has  a  plain,  positive 
meaning.  When  ordering  or  prescribing,  specify  SQUIBB'S. 


388        SQUIBB'S  MATERIA  MEDICA 

Tablets  Pepsin,  Bismuth  and  Charcoal,  Squibb 

C.T.  Per  1000          Per  500          Per  100 

Pepsin  2  gr.  1      These  tablets  possess  Digestive, 

Bismuth  Subnitrate  2  gr.  j-      Sedative  and  Absorbent  prop- 

Charcoal  2  gr.  J      erties,      and      are      employed 

chiefly    in    indigestion    due    to 

overeating,  with  acid  eructations,  pyrosis  and  flatulence.  Dose : 
1  or  2  tablets  immediately  after  meals  and  repeated  in  an  hour 
or  two  if  required. 

Tablets  Pepsin  and  Charcoal  Compound,  Squibb 

(Absorbent  Dyspepsia) 

C.T.  Per  1000  Per  500  Per  100 

Pepsin  1  gr.  1       Absorbent,       Digestive       and 

Charcoal  2  gr.  j-      Antizymotic;       in      flatulence, 

Sodium  Bicarbonate    21/2gr-J      indigestion,     acid     eructations, 

pyrosis,       fermentation,       etc. 

Our  process  of  manufacture  prevents  decomposition  of  the  pep- 
sin, and  our  tablets  will  be  found  therapeutically  active  and  free 
from  the  disagreeable  odor  common  to  most  brands  of  this 
combination.  Tablets  Pepsin  and  Charcoal  Compound  are  used 
in  all  types  of  simple  indigestion  due  to  overeating,  improper 
mastication  of  food,  or  to  weakened  conditions  of  the  digestive 
organs.  Dose:  1  or  2  tablets  before  or  after  meals,  repeated  in 
an  hour  or  two  if  required. 

Tablets  Pepsin  and  Nux.       See  Tablets  Nux  and  Pepsin. 

Tablets  Pepsin  and  Pancreatin  Compound,  Squibb 

C.T.  Per  1000       Per  500      Per  100 

Chocolate-coated  (C.  C.  T.) 


Pepsin  1  gr. 

Pancreatin  1  gr. 

Celery  Seed  1/4  gr. 

Calcium  Lactophosph.  1/4  gr. 


Used  in  delayed  or  imperfect 
digestion,  supplying  the  gas- 
tric and  pancreatic  ferments 
necessary  for  the  elaboration 


of  food.  The  calcium  lacto- 
phosphate  is  split  in  the  stomach,  producing  lactic  acid.  Dose : 
1  or  2  tablets  after  meals,  repeated  in  an  hour  or  two  if 
required. 

NOTE. — Combinations  of  pepsin  with  pancreatin  have  been 
criticized  in  some  quarters,  it  being  maintained  that  in  solution 
these  ferments  destroy  one  another,  and  that  under  physiologic 
conditions  they  are  chemically  impossible.  This  and  the  fol- 
lowing three  formulas  have  been  added  to  our  list  in  response 
to  many  demands  from  physicians.  In. this  connection  we  might 
state  that  we  do  not  approve  of  all  the  formulas  contained 
in  this  list,  from  a  strict  therapeutic  standpoint,  but  our  position 
as  purveyors  to  the  medical  profession  demands  that  we  sup- 
ply those  combinations  of  remedies  which  the  experience  of 
many  of  our  patrons  seems  to  indorse;  and  the  fact  that  we 
offer  such  combinations  in  response  to  an  existing  demand  in 
no  way  implies  any  discourtesy  to  contrary  opinions. 


SQUIBB'S  MATERIA  MEDICA        389 


Tablets    Pepsin    and 
Squibb 
C.T. 
Chocolate-coated  (C.  C.  T.) 


Pancreatin    Compound 

Per  1000       Per  500 


No.    2, 

Per  100 


Pepsin 
Pancreatin 
Bismuth  Subnitrate 
Ext.  Nux  Vomica 
Sodium  Bicarbonate 
Ginger 


3/4  gr. 
3/4  gr. 

VlO  gr. 

2gr. 

x/2  gr- 


quired.      (See    Note    at   end 
and  Pancreatin  Compound.) 


of 


Employed  for  relieving  gastric 
and  intestinal  dyspepsia,  and 
preventing  acid  eructations, 
flatulence  and  fermentation. 
Dose:  1  or  2  tablets  after 
meals,  repeated  at  hourly  in- 
tervals for  two  doses,  if  re- 
discussion  of  Tablets  Pepsin 


Tablets    Pepsin 
Squibb 


and 


C.T. 

Pepsin 

Pancreatin 

Ipecac 

Ginger 

Bismuth  Subnitrate 

Ext.  Nux  Vomica 

Wintergreen  Flavor 


Pancreatin 

(Digestive) 
Per  1000 


Compound    No.    3, 


Per  500 


Per  100 


2  gr.         A    combination    of    digestives 

1  gr.         and    stomachic    tonics    is    here 
VlOgr-         •presented.      (Dose:     1     or    2 

4/5  gr.   •      tablets      with        water      after 

2  gr.         meals,  repealed  in  an  hour  or 
1/10  gr-          two    if    required.       (See    note 

q.  s.  J  at  end  of  discussion  of  Tab- 
lets Pepsin  and  Pancreatin 
Compound.) 

Tablets    Pepsin,    Pancreatin    and    Lactic    Acid    Com- 
pound,    Squibb       (Digestive   Aromatic   5   gr.) 

Per  1000  Per  500  Per  100 

C.T. 

Pepsin  Saccharated     80  parts 
10  parts 
1  part 
1  part 
3  parts 
6  parts 


This  combination  is  said  to 
exert  a  beneficial  effect  in  cer- 
tain forms  of  dyspepsia. 
Dose :  1  or  2  tablets  imme- 
diately before  or  after  meals, 
repeated  in  an  hour  or  two  as 
required.  (See  Note  at  end 
of  discussion  of  Tablets  Pepsin  and  Pancreatin  Compound.) 

See    Tablets    Soda    Mint 


Pancreatin 

Acid  Lactic 

Diastase 

Acid  Hydrochloric 

Aromatic  Powder 


Tablets  Pepsin  and  Soda  Mint. 

and  Pepsin. 

Tablets  Phenacetin.     See  Tablets  Acetphenetidin. 

Tablets  Phenacetin  and  Salol.     See     Tablets     Salol 
Acetphonetidin. 


and 


The  founder  of  the  House  of  Squibb,  Dr.  Edward  R.  Squibb, 
not  only  had  high  ideals,  but  lived  and  labored  for  them;  and, 
in  the  words  of  William  Miller  Bartlett,  "the  House  of  Squibb 
stands  today  as  a  living  monument  to  the  honor,  integrity,  zeal 
and  devotion  of  its  founder." 


390       SQUIBB'S  MATERIA  MEDICA 

Tablets  Phenolphthalein  1   1/2  gr.,  Squibb 

C.T.  Per  1000  Per  500  Per  100 

Pink-coated  (P.  C.  T.) 

Phenolphthalein  has  been  extensively  used  as  a  laxative  and 
with  generally  good  results.  Its  freedom  from  bitter  .taste, 
absence  of  unpleasant  after-effects  and  small  dose  recommend 
its  use  for  children  and  delicate  women.  Clinical  reports  have 
demonstrated  its  value  as  a  safe  and  reliable  remedy.  Taken 
at  bedtime  it  usually  produces  an  evacuation  the  next  morning, 
although  in  obstinate  cases,  two  doses  during  the  day  are  some- 
times required.  Dose :  for  adults,  I  to  3  tablets  at  bedtime, 
repeated  if  necessary  after  breakfast  the  following  morning; 
for  children,  1/g  to  1  tablet,  reducing  the  dose  as  the  bowels 
resume  their  normal  functions. 

Tablets  Phenolphthalein  5  gr.,  Squibb 

C.T.  Per  1000  Per  500  Per  100 

Intended  for  more  resistant  cases  of  constipation.  Dose:  1  or  2 
tablets  at  bedtime;  in  the  beginning  of  the  treatment  and  in 
obstinate  cases,  I  or  2  tablets  after  supper,  repeated  at  bedtime, 
reducing  the  dose  as  the  bowels  resume  their  normal  functions. 

Tablets  Phenolphthalein  with  Chocolate,  Squibb 

C.T.  Per  1000  Per  500  Per  100 

Phenolphthalein  1  */2  8r-  \      The   addition   of   chocolate   to 

Chocolate  q.  s.  j       phenolphthalein      affords      an 

agreeable  method  of  admin- 
istering this  remedy  to  children  and  delicate  women.  The 
tablets  are  entirely  free  from  disagreeable  taste  and  may  be 
eaten  as  a  confection.  Their  action  has  been  found  prompt 
and  certain  and  no  disagreeable  after-effects  have  been  noticed. 
These  tablets  are  offered  to  offset  the  many  secret  preparations 
of  this  remedy.  Dose:  1  to  3  tablets  at  bedtime;  children, 
!/4  to  1  tablet. 

Tablets  Phosphorus  and  Nux  Vomica.      See  Tablets  Nux 
and  Phosphorus. 

Tablets  Physostigma  and  Triple   Bromides.    See  Tablets 
Triple  Bromides  and  Hyoscyamus  Compound. 

Tablets  Podophyllin   1/8  gr.,  Squibb 

T.T.  Per  1000        Per  500        Per  100 

Chocolate-coated  (C.  C.  T.) 

Cathartic  and  Cholagogue,  stimulating  the  liver,  causing  an 
increased  flow  of  bile  and  producing  free  action  of  the  bowels, 
appearing  to  act  principally  upon  the  small  intestines.  Podo- 
phyllin is  used  in  jaundice  and  congested  states  of  the  system, 
with  headache,  sluggish  liver  and  disordered  bowels,  with  flatu- 
lence and  colicky  pains.  In  small  doses  it  operates  with  little 
disturbance;  but  larger  doses  often  cause  griping,  which  may  be 
overcome  by  combination  with  other  agents.  (See  Cascara 
combinations.)  Dose :  1  tablet  after  meals;  or  1  or  2  tablets  at 
bedtime. 


SQUIBB'S  MATERIA  MEDICA       391 

Tablets  Podophyllin  1/4  gr.,  Squibb 

T.T.  Per  1000       Per  500      Per  100 

Chocolate-coated  (C.  C.  T.) 
Dose:    1    tablet  after  meals;   or  1    tablet  at  bedtime. 

Tablets  Potassium  Bromide  5  gr.,  Squibb 

C.T.  Per  1000  Per  500  Per  100 

Potassium  bromide  acts  as  a  Cerebral  and  Spinal  Sedative,  in 
small  doses  lessening  nervous  excitement,  quieting  the  brain,  the 
sexual  system  and  the  reflex  centers  of  the  spinal  cord;  in  large 
doses  it  paralyzes  the  cerebro-spinal  centers.  Hence  it  is  used 
in  excited  states  of  the  nervous  system,  to  allay  reflex  irritabil- 
ity; it  is  said  to  be  contra-indicated  in  excitement  due  to  nerve 
exhaustion.  It  is  given  with  good  results  in  wakefulness  caused 
by  overwork  or  worry,  in  the  convulsions  of  epilepsy,  Bright's 
disease,  and  the  convulsions  of  children,  whether  of  centric 
origin,  or  depending  upon  other  causes.  In  sexual  excitement, 
threatened  abortion,  nervous  headache,  hysteria  and  delirium  it 
is  also  deemed  valuable.  Dose:  1  to  3  tablets,  dissolved  in 
water,  repeated  every  hour  for  two  doses  if  necessary,  to  quiet 
the  nerves  and  induce  sleep;  for  convulsions,  3  to  6  tablets  in 
water,  repeated  if  necessary. 

Tablets  Potassium  Bromide  10  gr.,  Squibb 

C.T.  Per  1000  Per  500  Per  100 

Dose :    1   to  3  tablets  in  water,  as  required. 
Tablets  Potassium  Chlorate  5  gr.,  Squibb 

C.T.  Per  1000  Per  500  Per  100 

Screw-cap  pocket  vials,  per  doz., 

Potassium  chlorate  is  used  in  affections  of  the  mouth  and  throat, 
to  allay  inflammation;  it  is  a  popular  remedy  in  acute  sore 
throat,  with  huskiness  of  the  voice.  In  aphthae,  ulcerative 
stomatitis  and  mercurial  salivation  it  is  used  with  good  results; 
also  in  diphtheria  and  scarlatina.  It  is  also  employed  to  over- 
come the  vocal  fatigue  of  speakers  and  singers.  Dose:  1  tablet, 
dissolved  in  the  mouth,  every  two  qr  three  hours. 

Tablets  Potassium  Iodide  1  gr.,  Squibb 

C.T.  Per  1000  Per  500  Per  100 

Used  in  syphilis,  where  the  periosteum  or  fibrous  portions  of  the 
softer  organs  are  affected,  and  also  where  the  more  important 
organs  have  been  attacked;  in  diseases  of  the  glandular  system, 
and  to  cause  absorption  of  inflammatory  effusions,  as  in  pleurisy 
and  pericarditis;  for  the  relief  of  syphilitic  and  rheumatic  pains; 
and  in  asthma  and  lead  poisoning.  Dose:  for  children,  1  tab- 
let every  hour  with  water.  Dispense  in  glass. 


The  Squibb  Ideals  have  taken  concrete  form  in  the  Squibb 
Products;  these  are  universally  recognized  as  standards  of 
uniform  Purity  and  Efficacy,  that  is,  general  Excellence  and 
Reliability.  Specify  SQUIBB'S  when  prescribing  or  ordering. 


392        SQUIBB'S  MATERIA  MEDICA 

Tablets  Potassium  Iodide  2  gr.,  Squibb 

C.T.  Per  1000  Per  500  Per  100 

Dose :  1  tablet  every  hour  or  two  with  water,  for  syphilitic  skin 
diseases,  glandular  enlargements  and  chronic  rheumatism. 

Tablets  Potassium  Iodide  5  gr.,  Squibb 

C.T.  Per  1000  Per  500  Per  100 

Dose :  for  asthma,  1  tablet  every  three  or  four  hours  with 
water.  For  secondary  syphilitic  disease  and  chronic  rheumatism, 
1  tablet  with  water,  increasing  to  4,  after  meals. 

yTablets  Potassium  Iodide  and  Belladonna  Compound, 
Squibb  (Antiasthmatic) 

C.T.  Per  1000  Per  500  Per  100 

Potassium  Iodide  2  */2  gr.  1  Heroin  (diacetylmorphine) 
Heroin  Hydrochlor.  !/25  gr.  j-  acts  as  a  respiratory  sedative 
Ext.  Belladonna  VlO  gr.  J  and  antidyspneic ;  belladonna 

is  an  antispasmodic  and  stimu- 
lant to  the  respiratory  centers;  potassium  iodide  affects  the  secre- 
tions. Dose:  1  or  2  tablets,  with  water,  every  two  or  three 
hours.  (NOTE. — The  possibility  of  habit  formation  from  the 
prolonged  use  of  this  combination  should  not  be  overlooked.) 

Tablets     Potassium     Iodide    and     Lobelia    Compound, 
Squibb  (Antiasthmatic  No.  2) 

C.T.  Per  1000  Per  500  Per  100 


Potassium  Iodide  2  gr. 

Fluidextract  Lobelia      2  min. 
Potassium  Bromide  2  gr. 

Fl.Ext.Euphorb.Pilul.  3  min. 
Nitroglycerin  1/200  gr. 


This  formula,  a  slight  modifi- 
cation of  the  prescription  of 
Dr.  Hare,  has  been  used  in 
the  treatment  of  bronchial 
asthma  and  dyspnea  with 


apparent  success.  It  has  been 
used  for  many  years  by  a  large  class  of  physicians,  and  the 
repeated  demands  have  seemed  to  us  sufficient  reason  for  adding 
it  to  our  list.  Tablets  containing  potassium  iodide  are  liable 
to  become  damp  and  to  discolor  on  exposure  to  air,  hence  they 
should  be  kept  in  well-corked  containers  and  in  a  dry  place, 
and  they  should  be  dispensed  in  glass  only.  Dose:  I  or  2 
tablets  every  three  or  four  hours  with  water. 

Tablets  Potassium  Iodide  and  Mercury,  Squibb 

(Syphilis) 

C.T.  Per  1000  Per  500  Per  100 

Potassium  Iodide  2  */2  gr.  ]  Employed  in  syphilitic  diseases 
Corrosive  Sublimate  !/4o  gr.  j  in  the  later  stage,  and  in 

those    cases    where    the    iodide 

alone  does  not  control  the  symptoms.  Its  use  is  usually  per- 
sisted in  and  gradually  increased  to  the  point  of  tolerance,  or 
until  an  improvement  of  the  condition  occurs.  Dose :  1  tablet, 
with  water,  after  meals. 


SQUIBB'S  MATERIA  MEDICA        393 

Tablets    Potassium    Iodide    and    Mercury    Compound, 
Squibb 

(Mixed   Treatment;    Orthodox,   Dr.  S.  Sherwell) 
C.T.  Per  1000          Per  500          Per  100 


Potassium  Iodide  2  gr. 

Syrup  Iron  Iodide  5  mm. 

Mercury  Bichloride  */64  gr. 

Donovan's  Solution  2  mm. 

Tr.  Nux  Vomica  2  min. 


These  tablets  act  as  an  Alter- 
ative Tonic.  Their  effect  is 
a  stimulation  of  metabolism, 
resulting  in  improved  nutri- 
tion with  an  increased  ex- 


cretion of  the  products  of 
tissue  waste.  Upon  the  blood,  the  lymphatic  system  and  the 
skin,  their  action  is  said  to  be  marked;  in  syphilitic  and  scrofu- 
lous diseases,  chronic  rheumatism,  glandular  enlargements  and 
certain  skin  diseases  they  have  been  used  with  much  benefit. 
They  rarely  interfere  with  digestion,  and  they  may  be  admin- 
istered for  long  periods  it  is  claimed.  Owing  to  the  hygro- 
scopic nature  of  potassium  iodide  the  tablets  should  be  kept 
in  well-corked  bottles  and  in  a  dry  atmosphere;  and  they 
should  be  dispensed  in  glass.  Dose:  1  to  3  tablets  immediately 
after  meals,  with  a  glass  of  water. 

Tablets   Potassium   Iodide   and   Phytolacca  Compound 
Squibb  (Antirheumatic) 

C.T.  Per  1000  Per  500  Per  100 


Potassium  Iodide  2  gr. 

Ext.  Phytolacc  1  gr. 

Resin  Guaiac  3  gr. 

Colchicine  VlOO  gr. 

Digitalin  i/100  gr. 


These  tablets  are  employed  in 
acute  and  chronic  attacks  of 
rheumatism.  They  should  be 
preserved  in  well-corked  bot- 
tles and  dispensed  in  glass. 


Dose:  1  tablet  with  water 
every  two  hours  in  acute  attacks  until  the  symptoms  are  re- 
lieved, then  I  every  four  hours  for  not  more  than  three  doses. 
In  chronic  cases,  1  tablet  three  or  four  times  a  day. 

Tablets  Potassium  Permanganate  1  gr.,  Squibb 

C.T.  Per  1000  Per  500  Per  100 

Prepared  from  the  Squibb  special  quality  of  large  crystals  of 
permanganate,  and  loosely  compressed  in  order  to  dissolve 
quickly.  Disinfectant  and  Deodorizer.  Applied  as  a  wash  to 
sloughing  ulcers  and  as  an  injection  in  gonorrhea;  given  inter- 
nally in  diphtheria,  eruptive  fevers,  puerperal  fever  and  ery- 
sipelas. Most  frequently  employed  at  present  internally  in 
amenorrhea.  Dose :  in  zymotic  diseases,  1  tablet  with  water 
every  three  hours;  in  amenorrhea,  I  tablet  after  meals;  as  an 
injection,  2  to  4  tablets  in  a  half-pint  of  water. 


The  Squibb  Label  on  a  package  is  a  positive  guaranty  for  the 
uniform  Purity  and  Reliability  of  the  product.  We  make  only 
ONE  quality:  the  SQUIBB  quality;  and  our  prices  are  as  low 
as  they  can  be  made  for  that  quality.  Specify  SQUIBB'S. 


394       SQUIBB'S  MATERIA  MEDICA 

Tablets  Potassium  Permanganate  2  gr.,  Squibb 

Per  1000  Per  500  Per  100 

C.T. 

Dose:  as  an  Emmenagogue,  1  tablet  three  times  a  day  after 
meals  with  water;  as  an  injection,  2  to  4  tablets  in  a  pint  of 
water. 

Tablets  Potassium  Permanganate  3  gr.,  Squibb 

Per  1000  Per  500  Per  100 

C.T. 

Dose:  1  tablet  three  times  a  day.  For  disinfectant  solutions, 
1  to  3  tablets  in  a  pint  of  water. 

Tablets  Potassium  Permanganate  5  gr.,  Squibb 

Per  1000  Per  500  Per  100 

C.T. 

For  disinfectant  solutions,  1   to  2  tablets  in  a  quart  of  water. 
Tablets  Powder,  Dover's.      See  Tablets  Dover's  Powd«r. 

Tablets  Powder  Licorice  Compound.       See  Tablets  Com- 
pound Licorice  Powder. 

Tablets  Powder,  Tully's.      See  Tablets  Tully's. 

Tablets  Quinine  and  Acetanilid  Compound.       See   Tab- 
lets Aeetanilid  and  Quinine  Compound. 

Tablets  Quinine  and  Acetphenetidin.      See  Tablets  Acet- 
phenetidin  and  Quinine. 

•;  Tablets  Quinine  and  Camphor  Compound,  Squibb 
(Coryza  No.  3,  Dr.  Henry  J.  Kenyon) 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 

Quinine  Sulphate  !/2  gr.  1      A  favorite  remedy  in  the  treat- 

Camphor  1/2  gr.          ment    of    acute    coryza    with 

Morphine  Sulphate  1/(i4  gr.  j-  violent  sneezing  and  itching 
Atropine  Sulphate  1/2000  8r-  °f  'he  nostrils.  It  is  a  modi- 
Milk  Sugar  q.  s.  J  fication  of  the  rhinitis  for- 
mula, atropine  being  substi- 
tuted for  belladonna,  and  a  small  quantity  of  morphine  added. 
It  is  administered  in  repeated  doses  until  the  systemic  effect 
of  atropine  upon  the  throat  and  the  nasal  discharge  is  observed, 
and  then  at  less  frequent  intervals.  Dose :  1  tablet  every  hour 
until  the  throat  feels  dry,  then  every  2  to  4  hours  until  symptoms 
improve,  continuing  the  treatment  in  decreasing  doses  a  day  or 
two  after  the  discharge  has  ceased.  (NoTE. — These  tablets 
should  be  used  cautiously,  and  the  possible  formation  of  the 
morphine  habit  guarded  against.  For  those  physicians,  who  on 
general  principles,  object  to  the  administration  of  morphine  or 
heroin,  Tablets  Quinine,  Camphor  and  Belladonna  are  sug- 
gested.) 


SQUIBB'S  MATERIA  MEDICA        395 


•{•Tablets    Quinine    and    Camphor    Compound    No.    2, 
Squibb          (Coryza  No.  5,  Dr.  S.  MacCuen  Smith) 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 


Quinine    Sulphate 

Camphor 

Morphine  Sulphate 

Atropine  Sulphate 

Acid  Arsenous 

Strychnine  Sulphate  J/240  gr. 


VlO  gr. 

V4  gr- 

1/100  gr- 

Veoo  gr. 

1/24a  gr- 


These  tablets  have  been  used 
with  good  effects  in  recurrent 
attacks  of  coryza.  They  are 
given  until  the  systemic  ef- 
fect of  atropine  is  apparent, 
and  then  at  longer  intervals. 
For  those  physicians  who  ob- 
ject on  general  principles  to  the  administration  of  morphine, 
Tablets  Quinine  and  Camphor  Compound  No.  5  are  recommend- 
ed. Dose:  1  tablet  every  2  or  3  hours  until  the  symptoms  im- 
prove, or  4  tablets  at  bedtime,  with  plenty  of  water.  (See 
Note  under  Tablets  Quinine  and  Camphor  Compound,  above.) 


fTablets    Quinine 
Squibb 


and    Camphor    Compound    No.     3, 

(Coryza) 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 


Quinine  Sulphate 
Camphor 
Opium  Powdered 
Ammonium  Chloride 
Ext.  Belladonna 
Ext.  Aconite 


V2  gr. 

Va  gr- 

VlO  gr. 

V2  gr- 
VlO  gr. 
VlO  gr. 


Very  generally  regarded  as 
an  excellent  combination  for 
averting  attacks  of  acute 
coryza,  the  usual  symptoms 
of  muscular  soreness,  chilli- 
ness, hot,  dry  skin,  sneezing 
and  excessive  nasal  discharge 
being  promptly  arrested  if  the  tablets  are  taken  in  the  early 
stage.  Dose :  2  tablets  every  hour  or  two  until  relieved.  (See 
Note  under  Tablets  Quinine  and  Camphor  Compound,  above; 
also  Tablets  Quinine,  Camphor  and  Hyoscyamus  Compound). 

tTablets    Quinine    and    Camphor    Compound    No.    4, 
Squibb  (Coryza  No.  2) 

Per  1 000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 

Quinine  Sulphate  Vs  gr- 

Vs  gr- 

Vir, 


Camphor 

Opium   Powdered 
Ammonium  Chloride      */3  gr. 
Ext.  Belladonna  1/15  gr. 

Ext.  Aconite  i/15  gr. 


Dose :  for  sudden  colds,  2 
tablets,  then  1  every  hour 
until  the  acute  coryza  dis- 
appears. (See  Note  under 
Tablets  Quinine  and  Camphor 
Compound  above.) 


Squibb's  Tablets  are  made  from  the  Squibb  quality  of  ingredients 
and  by  improved  processes  that  insure  accurate  dosage  and 
rapid  and  complete  disintegration  or  solution  in  the  system, 
hence  prompt  and  full  therapeutic  effect.  Specify  SQUIBB'S. 


396       SQUIBB'S  MATERIA  MEDICA 

t  Tablets    Quinine    and    Camphor    Compound,    No.    5, 
Squibb  (Coryza  with   Heroin) 

C.T.  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 


Quinine  Sulphate  1/10  gr. 
Camphor  */4  8r- 

Heroin  Hydrochlor  VlOO  gr- 
Atropine  Sulphate  Veoo  gr 
Acid  Arsenous  */240  8r- 

Strychnine  Sulphate  V240  gr- 


These  tablets  are  commonly 
employed  in  recurrent  attacks 
of  coryza  with  severe  parox- 
ysms of  sneezing  and  itching 
of  the  nostrils.  They  are 
taken  until  the  systemic  effects 


of  atropine  are  observed,  and 
then  at  longer  intervals.  Atropine,  by  its  inhibitory  action 
upon  the  nerves  of  the  sensory  glands  of  the  nasal  mucous 
membrane,  arrests  the  discharge  from  the  nose.  Arsenic  is 
highly  recommended  by  Ringer  for  patients  who  suffer  from 
frequent  attacks  of  cold  in  the  head.  Camphor  and  quinine 
act  as  mild  antipyretics.  Heroin  serves  to  allay  cough  and 
inflammation.  Dose:  1  tablet  every  hour,  for  colds  in  the 
head,  until  the  throat  feels  dry,  then  every  two  or  three  hours, 
continuing  for  a  day  or  two  after  the  acute  coryza  disappears. 
(See  Note  under  Tablets  Quinine  and  Camphor  Compound, 
above.) 

Tablets     Quinine,     Camphor     and     Belladonna,     Full 
Strength,  Squibb          (Rhinitis,  Full  Strength) 

C.T.  Per  1 000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 

Quinine  Sulphate  1/2  gr.  "|       These    tablets    are    just    twice 

Camphor  */2  gr.  >      the     strength     of     the     half- 

Fluidext.  Belladonna  1/4  min.  J       strength        tablets        regularly 

supplied,     and     are     intended 

for  use  particularly  in  robust  patients.  Dose :  1  tablet  every 
half  hour  for  3  or  4  doses,  or  until  the  throat  becomes  dry, 
then  in  diminishing  doses  until  the  nasal  discharge  ceases. 

*  Tablets    Quinine,    Camphor    and    Belladonna,     Half 
Strength,  Squibb 

(Rhinitis,  Half  Strength,  Dr.  Lincoln) 
T.T.  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 

Quinine  Sulphate  */4  gr.  "I       Acute    attacks    of   rhinitis    are 

Camphor  1/4  gr.  }•      as    a    rule   markedly   benefited 

Fluidext.  Belladonna  1/8  min.  J       by  these  tablets,  it  is  claimed. 

Taken  at  the  onset  and  per- 
sisted in  until  the  throat  becomes  dry,  these  tablets  have  been 
found  to  check  the  sneezing  and  discharge  from  the  nostrils  and 
frequently  to  cut  short  the  attack.  Dose:  1  tablet  every  half 
hour  for  four  doses,  then  every  hour  or  two  until  the  constitu- 
tional effect  of  belladonna  is  observed,  when  the  interval  is 
lengthened  to  three  hours  and  the  tablets  continued  until  the 
discharge  from  the  nose  disappears. 


SQUIBB'S  MATERIA  MEDICA       397 

Tablets    Quinine,    Camphor    and     Hyoscyamus    Com- 
pound, Squibb         (Coryza  Modified) 

Per  1000        Per  500        Per  100 
Chocolate-coated   (C.  C.  T.) 


Quinine  Sulphate  J/2  gr. 

Camphor  J/2  gr. 

Ext.  Hyoscyamus         !/io  gr. 

Ammonium  Chloride     J/2  gr. 

Ext.  Belladonna  1/10  gr- 

Ext.  Aconite  i/lO  gr. 


This  is  a  modification  of  Tab- 
lets Quinine  and  Camphor 
Compound  No.  3  (Coryza), 
the  powdered  opium,  being  re- 
placed by  an  equal  quantity  of 


extract  hyoscyamus  for  the 
benefit  of  those  physicians  ob- 
jecting to  the  use  of  opium.  Dose:  2  tablets  with  water, 
every  hour  or  two  until  the  coryza  symptoms  are  relieved. 

Tablets  Quinine  and  Capsicum,  Squibb 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 

Quinine  Sulphate  2  gr.  1      The   addition   of    capsicum    to 

Capsicum  1/4  gr.  j       quinine    increases    its    physio- 

logical action,  making  a  com- 
bination useful  in  malarial  affections  where  the  digestive  action 
is  weak  and  assimilation  imperfect.  Capsicum  acts  as  a  salivary 
and  gastric  stimulant,  improves  the  appetite,  hastens  digestion, 
and  increases  the  stomach's  power  of  absorption.  Tablets 
Quinine  and  Capsicum  Squibb  are  used  in  the  treatment  of 
malaria,  and  also  as  a  prophylactic  in  patients  exposed  to 
malarial  influences.  Dose:  1  to  3  tablets,  with  water,  every 
three  or  four  hours. 

Tablets  Quinine  and  Capsicum  No.  2,  Squibb 

(Dr.   Wm.   F.   Kier) 

'  White  or  Pink-coated  Per  1000       Per  500       Per  100 

(W.  C.  T.  or  P.  C.  T.) 

Quinine  Bisulphate  3  gr.  1      These     tablets     contain     more 

Capsicum  1/4  gr.  j       quinine   than   Tablets  Quinine 

and  Capsicum  and   are  hence 

more   active   as   an   Antiperiodic.      Dose:     1    to   3    tablets   with 
water  every  3  or  4  hours. 

Tablets  Quinine  and  Iron  Compound,  Squibb 

(Aiken's  Tonic) 

C.T.  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 


Quinine  Sulphate  1  gr. 

Iron  Reduced  2/3  gr. 

Acid  Arsenous  1/50  gr. 

Strychnine  Sulphate  VoOgi"' 

Extract  Gentian  */4  gr. 


This  combination  is  consid- 
ered an  excellent  tonic  in  all 
weakened  conditions  of  the 
system — overcoming  anorexia, 
improving  nutrition,  stimu- 


lating    metabolism     and     pro- 
ducing a  general   improvement  in  health.     It  is  used  in   simple 

This  house  supplies  only  one  quality  of  each  product:  that  best 
suited  to  the  purposes  intended.  The  specification  "Squibb's" 
is  not  open  to  various  interpretations;  it  has  a  plain,  posi- 
tive meaning.  Therefore,  when  prescribing,  specify  SQUIBB'S. 


398       SQUIBB'S  MATERIA  MEDICA 
Tablets  Quinine  and  Iron  Compound,  Squibb  (Cont.) 

anemia,  debility,  and  convalescence  from  acute  disease.  Special 
attention  is  given  to  the  trituration  of  the  ingredients  so  as  to 
insure  thorough  subdivision  and  accurate  dosage.  Dose:  1  or  2 
tablets  three  times  a  day,  ten  minutes  before  meals. 

Tablets    Quinine   and    Iron   Compound   with   Cascarin, 
Squibb  (Aiken's  Tonic  Laxative) 

C.T.  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 


Quinine  Sulphate  1  gr. 

Iron  Reduced  2/s  gr. 

Cascarin  1/2  gr. 

Acid  Arsenous  VoO  gr. 

Strychnine  Sulphate  Vso  gr. 

Extract  Gentian  !/4  gr. 


This  is  a  modification  of  the 
time-honored  Aiken's  Tonic 
formula,  and  is  adapted  to 
those  cases  where  the  patient 
habitually  suffers  from  con- 
stipation, or  where  the  re- 


duced iron  in  the  formula 
produces  this  effect.  Dose:  1  or  2  tablets  three  times  daily, 
before  meals. 

Tablets  Quinine  and  Salol,  Squibb 

C.T.  Per  1000       Per  500       Per  100 

Quinine  Sulphate  2J/2  gr.  1  Quinine  and  salol  have  long 
Salol  (Phenyl  {•  been  used  in  combination  in 

Salicyl.)  2J/2  gr.  J      the    treatment    of    acute    and 

chronic  rheumatism,  for  the  re- 
lief of  neuralgic  pains,  and  as  a  safeguard  against  infection  in 
malarial  climates.  As  it  is  of  the  utmost  importance  that  tablets 
of  this  nature  break  up  readily  in  the  system,  special  pains 
are  taken  to  cause  these  tablets  and  others  of  similar  composi- 
tion to  disintegrate  at  once  in  the  presence  of  moisture.  This 
can  readily  be  demonstrated  by  dropping  a  tablet  in  a  spoonful 
of  water  at  body  temperature;  should  the  tablet  not  readily 
respond  to  this  test  it  should  be  condemned  as  being  unfit  for 
use.  Dose :  as  an  Analgesic  or  Antipyretic,  1  tablet  every 
half  hour  for  three  doses,  then  every  two  to  four  hours;  as  a 
prophylactic,  1  tablet  after  meals  and  at  bedtime. 

Tablets  Quinine,  Strychnine  and  Iron.      See  Tablets  Iron, 
Quinine  and  Strychnine. 

Tablets  Quinine  Bisulphate  1  gr.,  Squibb 

C.T.OfC.C.T.  Per   1000         Per  500         Per   100 

Quinine  bisulphate  is  usually  preferred  to  the  sulphate  where 
the  acid  secretion  of  the  stomach  is  deficient,  its  more  rapid 
absorption  compensating  for  the  lesser  quantity  of  quinine  alka- 
loid it  contains.  Employed  as  a  tonic  in  debilitated  conditions 
of  the  system,  and  for  its  antiperiodic  and  antipyretic  action  in 
sufficient  dosage  in  malarial  affections.  Dose:  1  tablet  after 
meals  for  Tonic  and  Antiperiodic  effect;  as  an  Antipyretic  in 
children,  1  or  2  tablets  every  two  hours. 


SQUIBB'S  MATERIA  MEDICA       399 

Tablets  Quinine  Bisulphate  2  gr.,  Squibb 

P«r1000  Per  500  Per  100 

C.  T.  or  C.  C.  T. 

Dose:  1  tablet  after  meals,  as  a  Tonic;  in  malarial  affections 
and  as  an  Antipyretic  in  fever,  1  to  5  tablets  every  th*ee  or  four 
hours. 

Tablets  Quinine  Bisulphate  3  gr.,  Squibb 

Per  1000  Per  500  Per  100 

C.  T.  or  C.  C.  T. 

Dose:  1  tablet  every  two  or  three  hours,  as  an  Antipyretic; 
as  an  Antiperiodic,  1  tablet  after  meals. 

Tablets  Quinine  Bisulphate  5  gr.,  Squibb 

Per  1 000  Per  500  Per  100 

C.  T.  or  C.  C.  T. 

Dose:  as  an  Antipyretic,  1  tablet  every  two  or  three  hours; 
in  ague,  I  tablet  six,  four  and  two  hours  before  the  expected 
paroxysm. 

Tablets  Quinine  Sulphate  1/10  gr.,  Squibb 

Per  1000  Per  500  Per  100 

C.  T.  or  C.  C.  T. 

Antiperiodic  and  Bitter  Tonic,  for  children.  Dose:  1  tablet 
three  or  four  times  a  day,  as  a  tonic;  as  an  Antiperiodic,  1 
tablet  every  hour. 

Tablets  Quinine  Sulphate  1/2  gr.,  Squibb 

Per  1000  Per  500          Per  100 

C.  T.  or  C.  C.  T. 
Dose:    1   tablet  every  hour  for  malaria  in  children. 

Tablets  Quinine  Sulphate  1  gr.,  Squibb 

Per  1000  Per  500  Per  100 

C.  T.,  C.  C.  T.  or  P.  C.  T. 

Dose:  1  or  2  tablets  every  two  hours,  in  malarial  fevers,  de- 
creasing as  symptoms  improve  or  if  ringing  in  the  ears  occurs. 

Tablets  Quinine  Sulphate  2  gr.,  Squibb 

Per  1000       Per  500       Per  100 
C.  T.,  C.  C.  T.,  P.  C.  T.  or  W.  C.  T. 

Dose:  as  a  general  tonic,  1  tablet  after  meals  and  at  bedtime; 
for  malaria,  1  to  5  tablets,  every  three  or  four  hours;  for  sudden 
colds,  1  to  5  tablets  at  bedtime  with  10  grains  Dover's  powder. 


The  prices  of  the  Squibb  Products  are  in  all  instances  as  low  as 
the  quality  and  quantity  of  ingredients  and  the  expense  of  man- 
ufacture allow.  They  include  containers,  packing  and  boxing.  When 
ordering  or  prescribing  medicinal  products,  specify  SQUIBB'S. 


400       SQUIBB'S  MATERIA  MEDICA 

Tablets  Quinine  Sulphate  3  gr.,  Squibb 

C.  T.  or  C.  C.  T.  Per  1 000  Per  500  Per  1 00 

Dose :  as  tonic,  1  tablet  after  meals  and  at  bedtime ;  in  malaria, 
1  to  3  tablets  every  3  or  4  hours;  in  colds,  I  to  3  tablets  at  bed- 
time, with  10  grains  Dover's  powder. 

Tablets  Quinine  Sulphate  5  gr.,  Squibb 

C.  T.  or  C.  C.  T.  Per  1 000  Per  500  Per  1 00 

Dose :  for  malaria,  1  tablet  six,  four  and  two  hours  before  the 
expected  attack. 

Tablets  Rheumatism.      See    Tablets    Sodium    Salicylate    and 
Colchicme  Compound. 

Tablets  Rhinitis,  Full  Strength.     See     Tablets     Quinine, 
Camphor  and  Belladonna,  Full  Strength. 

Tablets  Rhinitis,  Half  Strength.  See    Tablets    Qui- 

nine, Camphor  and  Belladonna,   Half  Strength. 

Tablets  Rhinitis,  Infants'.     See  Tablets  Aconite  and  Cam- 
phor Compound  No.  2. 

Tablets  Rhubarb  Compound,  Squibb 

C.T.  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 

Rhubarb  2  gr.  1       For  the  treatment  of  habitual 

Myrrh  1  gr.  1       indigestion    with    constipation. 

Aloes  Purified  1  */2  8r-  f      Rhubarb    is    a    tonic    laxative. 

Oil  Peppermint  l/io  mm<  J  ^  mav  be  given  f°r  l°ng  pe- 
riods, it  is  said,  without  weak- 
ening the  bowels.  It  acts  pleasantly  without  griping  and  without 
tenesmus.  Combined  with  aloes,  which  acts  upon  the  lower 
bowel  and  the  rectum,  it  stimulates  all  parts  of  the  intestinal 
tract.  Myrrh  acts  as  a  mild  astringent  and  peppermint  modifies 
the  laxative  action.  Dose :  1  tablet  after  meals. 

Tablets  Rhubarb  and  Ipecac  Compound,  Squibb 

(Roosevelt  Hospital) 

C.T.  Per  1000  Per  500  Per  100 

Rhubarb  1  gr.    1     Special    attention    is    given    to 

Ipecac  1/g  gr.    I     all      our      rhubarb      combina- 

Sodium  Bicarbonate  5  gr.  |  tions,  and  they  will  be  found 
Oil  Peppermint  I/OQ  min.  J  superior  products.  Not  alone 

is    the    rhubarb    used    of    best 

quality,  but  in  the  manufacture  decomposition  of  the  ingredients 
is  prevented  and  the  tablets  present  a  handsome  appearance  and 
are  very  acceptable  to  the  taste.  This  combination  is  used  in 
habitual  indigestion  with  loss  of  appetite,  coated  tongue,  bad 
breath  and  constipation,  stimulating  digestion,  preventing  fer- 
mentation, correcting  acidity  and  relieving  constipation.  The 
cutaneous  eruptions  observed  on  the  faces  of  patients  with 
chronic  dyspepsia  are  said  to  be  greatly  reduced,  often  cured,  by 
treatment  with  these  tablets.  Dose:  1  tablet  after  meals. 


SQUIBB'S  MATERIA  MEDICA       401 


Tablets  Rhubarb  and  Ipecac  Compound  No.  2,  Squibb 

(Roosevelt  Hospital) 

Per  1000  Per  500  Per  100 

C.T. 
Rhubarb 
Ipecac 
Sodium  Bicarbonate 


2gr. 

1/0 


A     modification     of     Tablets 
Rhubarb     and     Ipecac    Com- 
5  gr.  I*     pound    Squibb;     the    quantity 

Oil  Peppermint          !/20  min.  J      of     rhubarb     being     doubled. 

Preferred  where  the  constipa- 
tion is  more  pronounced.     Dose:    1   tablet  after  meals. 


Tablets  Rhubarb  and  Ipecac  Compound  No.  3,  Squibb 

(Roosevelt  Hospital) 

Per  1000  Per  500  Per  100 

C.T. 
Rhubarb 
Ipecac 
Sodium  Bicarbonate 


2gr. 


A  modification  of  the  Rhu- 
barb and  Ipecac  Compound 
formula,  the  change  consist- 
ing in  the  increase  of  the 
quantity  of  rhubarb  and 
ipecac  and  the  addition  of 
tincture  of  nux  vomica,  thus 
increasing  its  laxative  effect,  and  rendering  the  combination  of 
much  more  service  in  dyspepsia.  Dose :  1  or  2  tablets  with 
meals  or  immediately  after. 


5gr. 
Tr.  Nux  Vom.  US.P.  '90 

5  min. 
Oil  Peppermint          I/OQ  min. 


Tablets  Rhubarb  and  Ipecac  Compound  No.  4,  Squibb 
(Dr.  M.  L.  Goodkind) 

Per  1000  Per  500  Per  100 

C.T. 
Rhubarb 
Ipecac 

Sodium  Bicarbonate 
Extract  Nux  Vomica 
Oil  Peppermint 


Vs 

5gr- 


Fluidext.  Cascara 


lO  mn. 
5  min. 


This  formula  is  a  modifica- 
tion of  our  Rhubarb  and 
Ipecac  Compound,  1/4  grain 
of  extract  of  nux  vomica  and 
5  minims  of  fluidextract  of 
cascara  being  added.  The 
tablets  are  thereby  increased 
proved  an  excellent  remedy  in 
an  atonic  condition  of  the  ali- 
mentary canal.  Cascara  sagrada  acts  as  a  tonic  laxative  and 
its  continued  use  is  not  known  to  debilitate  the  bowels.  In 
constipation  attended  by  flatulence,  headache  and  indigestion 
these  tablets  usually  give  satisfactory  results,  it  is  reported. 
Dose :  1  tablet  just  before  meals,  decreasing  the  frequency  of 
the  dose  as  the  case  requires. 


in    laxative    action    and    have 
constipation    dependent    upon 


If  difficulty  is  experienced  In  procuring  any  Squibb  product, 
in  the  original  packages  here  listed,  please  notify  us;  we 
shall  see  that  your  wants  are  met  promptly  and  satisfactorily. 


402        SQUIBB'S  MATERIA  MEDICA 


Tablets   Rhubarb  and   Ipecac  Compound   No.   4,   Half 
Strength,  Squibb     (Dr.  M.  L.  Goodkind) 

Per  1000       Per  500       Per  100 


Chocolate-coated  (C.  C.  T.) 

Rhubarb  */2  gr. 

Ipecac  Vl6  gr- 

Sodium  Bicarbonate  2^2  gr- 
Extract  Nux  Vomica  */8  gr. 
Oil  Peppermint  !/2o  min. 
Fluidext.  Cascara  2^2  min. 


This  formula  is  the  same  as 
the  preceding  one,  with  all 
the  ingredients  reduced  one- 
half.  Dose:  I  or  2  tablets 
immediately  before  meals  with 
water. 


Tablets  Rhubarb  and  Magnesia  Compound,  Squibb 

(Neutralizing) 


P«rlOOO 


Per  500 


Per  100 


C.T. 

Rhubarb 

Igr- 

Magnesia  Calcined 

Igr. 

Sodium  Bicarbonate 

I38'' 

Cardamom 

Oil  Peppermint 

q.  s. 

This  formula  is  a  mild  Ant- 
acid, Laxative  and  Corrigent 
used  in  dyspepsia  attended 
with  constipation,  fermenta- 
tion and  flatulence,  in  chil- 
dren or  in  adults.  In  case 
the  tablets  cannot  be  swallowed,  they  may  be  crushed  to  a 
powder  and  given  with  a  swallow  of  water.  We  call  attention 
to  the  quality  of  the  rhubarb  contained  in  these  tablets;  it  is 
the  best  Shensi  rhubarb  obtainable.  Dose :  I  or  2  tablets  after 
meals,  repeated  in  an  hour  or  two  if  required. 

Tablets  Rhubarb  and  Soda,  Squibb 


Per  1 000       Per  500      -Per  100 


C.T. 


Chocolate-coated  (C.  C.  T.) 

Rhubarb  1  */2  gr 

Sodium  Bicarbonate     1  */2  gr. 
Oil  Peppermint  q.  s 


An  Alkaline  Laxative  and 
Stomachic,  employed  in  indi- 
gestion with  constipation,  and 
the  usual  accompanying 
symptoms  of  loss  of  appetite,  coated  tongue,  foul  breath  and 
headache.  Also  as  laxative  for  children  or  adults;  acting  upon 
the  bowels  without  griping.  Their  continued  use  does  not  debil- 
itate the  intestinal  functions,  it  is  claimed.  Dose:  for  children, 
depending  on  age,  I  to  2  tablets;  for  adults,  2.  to  5  tablets  at 
bedtime  or  in  divided  doses  after  meals. 


Tablets  Rhubarb  and  Soda  No.  2,  Squibb 

Per  1000      Per  500 
C.T. 

3gr. 


Per  100 


Rhubarb 

Sodium  Bicarbonate 
Oil  Peppermint 


q.  s. 


These  tablets  are  just  twice 
the  strength  of  the  preceding; 
their  action  and  uses  are  the 
same.  Dose :  1  or  2  tablets 


after  meals,  or  2  tablets  at  bedtime,  with  water. 


SQUIBB'S  MATERIA  MEDICA       403 

Tablets  Rhubarb  and  Soda  No.  3,  Squibb 

Per  1000          Per  500          Per  100 
C.T. 

Rhubarb  2  */2  gr.  ]       These      tablets      contain      the 

Sodium  Bicarbonate    2  */2  gr.  ?•      same    ingredients   as    in    Tab- 
Oil  Peppermint  q.  s.  J       lets    Rhubarb    and   Soda,    but 

in   larger  quantities,   and  their 
uses  are  the  same.     Dose:     1   or  2  tablets  after  meals. 

Tablets  Rhubarb  and  Sodium  Bicarbonate  Compound, 
Squibb  (Antidyspeptic) 

Per  1000      Per  500      Per  100 
C.T. 
Chocolate-coated  (C.  C.  T.) 


Extract  Rhubarb  */4  gr. 

Sodium  Bicarbonate  2  gr. 

Strychnine  Sulphate  i/GO  gr. 

Ipecac  VlO  gr. 

Capsicum  */4  gr. 

Extract  Gentian  1/2  gr- 


Anorexia,  faulty  digestion 
and  hepatic  torpor  with  con- 
stipation are  the  indications 
for  these  tablets.  The  union 
of  gentian,  a  pure  bitter  tonic, 
capsicum,  a  salivary  and  di- 


gestive stimulant,  and  ipecac, 
a  gastric  and  hepatic  corrective,  makes  a  tablet  which  improves 
the  appetite  and  digestive  action.  Strychnine  is  known  to  act 
as  a  stimulant  to  the  peptic  cells,  to  overcome  muscular  atony 
and  increase  peristalsis.  Rhubarb  is  both  tonic  and  laxative. 
Sodium  bicarbonate  neutralizes  hyperacidity.  Tablets  Rhu- 
barb and  Sodium  Bicarbonate  Compound  are  used  in  atonic 
dyspepsia,  in  gastritis  from  abuse  of  alcohol,  and  in  acute  at- 
tacks of  indigestion  due  to  overeating  or  imperfect  mastication. 
Dose :  1  tablet  half  an  hour  before  meals,  followed  by  1  half  an 
hour  after  meals  if  required. 

Tablets  Saccharin  (Soluble)  Y4  gr.,  Squibb 

Per   1000         Per  500         Per  100 
C.  T. 

Each  tablet  equals  a  lump  of  sugar  in  sweetening  power.  Con- 
venient for  use  in  the  army,  on  the  battlefield  and  other 
places  where  sugar  is  difficult  to  obtain.  Used  medicinally  in 
diabetes  and  obesity,  and  in  dyspeptic  condition  where  sugar 
is  contra-indicated. 

Tablets  Saccharin  (Soluble)  1/2  gr.,  Squibb 

Per  1000  Per  500  Per  100 

C.T. 
Screw-cap  pocket  vials  per  doz. 


The  Squibb  products  are  recognized  everywhere  as  the  Quality 
Standard.  They  are  of  uniform  purity  and  strength,  hence 
therapeutically  dependable.  When  ordering  or  prescribing  med- 
icinal products,  you  will  do  well  always  to  specify  SQUIBB'S. 


404        SQUIBB'S  MATERIA  MEDICA 

Tablets  Saccharin  (Soluble)  1  gr.,  Squibb 

C.T.  Per  1000  Per  500  Per  100 

Dose:    1    tablet  for  a  cup  of  coffee  or  tea. 

Tablets  Salol  (Phenyl  Salicylate)  1  gr.,  Squibb 

T.T.  Per  1000  Per  500  Per  100 

Salol  is  regarded  as  a  safe  and  efficient  Intestinal  Antiseptic.  It 
is  not  affected  by  the  gastric  juice,  but  is  decomposed  by  the 
alkaline  secretions  of  the  small  intestine  into  salicylic  acid  and 
phenol,  which  products  tend  to  correct  morbid  conditions  of 
the  intestinal  tract.  It  is  also  used  in  the  treatment  of  acute 
and  chronic  rheumatism,  lumbago  and  sciatica.  Owing  to  the 
fact  that  salol  is  largely  excreted  by  the  kidneys  as  salicyluric 
acid,  it  is  used  in  chronic  inflammation  of  the  bladder,  gonorrhea 
and  catheter  fever.  It  rarely  produces  nausea  or  gastric  dis- 
turbance it  is  stated;  but  where  the  renal  functions  are  im- 
paired or  constipation  exists,  toxic  action  may  manifest  itself. 
Tablets  Salol  Squibb  disintegrate  rapidly,  and  are  the  best 
method  for  administering  this  remedy.  Dose :  1  to  4  tablets 
every  two  or  three  hours.  [NoTE:  Tablets  containing  salol 
should  not  be  exposed  to  direct  sunlight  or  kept  in  a  warm 
place,  else  they  will  not  disintegrate  quickly.] 

Tablets  Salol  (Phenyl  Salicylate)  2%  gr.,  Squibb 

C.T.  Per  1000  Per  500  Per  100 

Dose :  as  an  Intestinal  Antiseptic,  1  or  2  tablets  an  hour  before 
meals  and  two  hours  afterwards;  for  rheumatism,  1  or  2  tablets 
every  hour  until  relieved;  for  catheter  fever,  gonorrhea  and 
inflammation  of  the  bladder,  1  tablet  every  two  hours. 

Tablets  Salol  (Phenyl  Salicylate)   5  gr.,  Squibb 

C.T.  Per  1 000  Per  500  Per  100 

Dose:  as  an  Intestinal  Antiseptic,  1  tablet  every  three  or  four 
hours;  in  acute  rheumatism,  1  to  4  tablets  every  two  or  three 
hours. 

Tablets  Salol  and  Acetanilid.      See  Tablets  Acetanilid  and 
Salol. 

Tablets  Salol  and  Acetphenetidin,  Squibb 

(Salol  and  Phenacetin)        Per  1000        Per  500        Per  100 
C.T. 

Salol   (Phenyl  This  tablet  is  a  favorite  com- 

Salicyl.)  2]/2  8r<  f     bination    for    reflex    neuralgic 

Acetphenetidin  2J/2  gr.  J      and    for    rheumatic    pains,    as 

well  as  in  the  febrile  stage  of 

grip,  in  intercostal  neuralgia,  headache  due  to  intestinal  fermen- 
tation, and  in  acute  attacks  of  tonsillitis,  allaying  pain,  quieting 
restlessness  and  subduing  fever.  Dose:  1  tablet  every  half 
hour  for  two  or  three  doses;  then  every  two  or  three  hours  until 
relieved.  These  tablets  should  be  kept  in  a  cool  place,  as  salol 
melts  at  about  106°  F. 


SQUIBB'S  MATERIA  MEDICA       405 

Tablets  Salol  and  Copaiba  Half-Strength,  Squibb 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 


Salol  (Phenyl  Salicyl.)   1  gr. 

Copaiba  1  gr. 

Pepsin  !/4  gr- 

Extract  Kava  i/2  gr. 

in  combination  with  Oleoresin 
Cubeb,  Oil  Sandalwood 
and  Oil  Wintergreen. 


These  tablets  are  used  in 
catarrhal  and  infectious  con- 
ditions of  the  urinary  organs. 
They  are  skilfully  prepared 
and  represent  the  full  thera- 
peutic activity  of  the  formula, 
and  the  coating  retains  the 


volatile  ingredients  unaltered. 
They  should  be  kept  in  a  cool  place.  Dose :  2  or  3  tablets  after 
meals,  with  plenty  of  water,  three  or  four  times  a  day. 

Tablets    Salol    and    Phenacetin.      See    Tablets    Salol    and 
Acetphenetidin. 

Tablets  Salol  and  Quinine.     See  Tablets  Quinine  and  Salol. 

Tablets  Salt  24  gr.,  Squibb  Per  500          Per  100 

C.T. 

These  tablets  are  intended  for  preparing  normal  physiological 
salt  solution.  Dissolved  in  water  in  the  proportion  of  2  tablets 
in  one  pint,  they  yield  a  solution  containing  about  six-tenths 
(0.6)  of  one  percent,  of  pure  sodium  chloride;  2  tablets  dis- 
solved in  12  fl.  ozs.  of  water  make  about  0.85  percent,  solution. 
Distilled  or  sterile  water  should  be  used  in  preparing  the  solu- 
tion, which  should  be  strained  through  absorbent  cotton. 

Tablets  Santonin  1/10  gr.,  Squibb 

Per  1000  Per  500  Per  100 

C.T. 

Santonin  is  employed  for  the  destruction  of  round  and  thread 
worms.  It  is  considered  one  of  the  best  remedies,  but  in  poorly 
nourished  children  must  be  given  with  caution,  as  it  occasionally 
causes  vomiting,  headache,  etc.  It  is  preferably  given  in  the 
morning  on  an  empty  stomach,  and  followed  in  about  four  hours 
by  a  dose  of  castor  oil  or  some  other  purgative.  Dose:  1  to  5 
tablets,  depending  on  the  age  of  child. 

Tablets  Santonin  1/4  gr.,  Squibb 

Per  1000  Per  500  Per  100 

T.T. 

Dose:  1  or  2  tablets,  according  to  age,  every  two  hours  for  not 
more  than  four  doses,  followed  by  a  cathartic. 


Since  we  make  only  one  quality  of  each  product,  that  best 
suited  to  the  purposes  intended,  the  specification  'Squibb's" 
is  not  open  to  various  interpretations,  but  has  a  plain,  positive 
meaning.  When  ordering  or  prescribing,  specify  SQUIBB'S. 


406       SQUIBB'S  MATERIA  MEDICA 

Tablets  Santonin  1/2  gr.,  Squibb 

T.T.  Per  1000  Per  500  Per  100 

Dose:  For  older  children,  1  or  2  tablets,  according  to  age, 
every  two  hours,  for  not  more  than  four  doses,  followed  by  a 
purgative. 

Tablets  Santonin  and  Calomel,  Squibb 

T.T.  Per  1000  Per  500  Per  100 

Santonin  1/2  gr.  j      Calomel      increases     the     an- 

Calomel  !/2  gr.  }       thelmintic   action  of  Santonin, 

and  increases  its  efficacy  as  a 

purgative.  These  tablets  are  used  against  round  and  thread 
worms.  Dose :  1  or  2  tablets  every  two  hours  for  not  more  than 
four  doses.  If  bowels  do  not  move  after  the  last  dose,  a  dose  of 
castor  oil  or  a  saline  cathartic  should  be  given. 

Tablets  Santonin  and  Calomel  No.  2,  Squibb 

C.T.  Per  1000            Per  500           Per  100 

Santonin  1  gr.  {      Dose :    1    tablet  repeated  after 

Calomel  1  gr.  }      two  hours  if   necessary. 

Tablets  Sciatica.     See   Tablets   Aconite    and    Colchicum    Com- 
pound. 

Tablets  Sedative.      See  Tablets  Triple  Bromides  and  Cannabis 
Compound. 

Tablets  Sedative  No.  2.       See  Tablets  Camphor,  Hyoscyamus 
and  Sumbul  Compound. 

Tablets  Sedative  No.  3.       See  Tablets  Asafetida  and  Valer- 
ian Compound. 

Tablets  Silver  Nitrate  1  gr.,  Squibb 

C.T.  Per  1000  Per  500  Per  100 

These  tablets  are  made  from  pure  silver  nitrate  by  careful  com- 
pression and  without  undue  exposure;  they  dissolve  readily  in 
distilled  water,  yielding  a  clear  solution.  One  tablet  dissolved 
in  an  ounce  of  water  yields  about  a  1  :  500  solution.  They  are 
used  for  the  extemporaneous  preparation  of  collyria  or  injections, 
for  which  purpose  they  are  admirably  adapted.  They  darken 
by  exposure  to  light,  and  are  therefore  furnished  in  black 
bottles.  A  slight  blackening  of  the  surface  of  the  tablets,  which 
is  liable  to  occur  in  process  of  manufacture,  should  not  condemn 
the  tablet,  as  it  usually  occurs  on  the  surface  only  and  is  diffi- 
cult to  prevent.  Directions:  For  solution,  1  tablet  dissolved  in 
100  minims  of  water  or  5  tablets  to  1  fluidounce  yields  about 
a  1  percent,  solution,  and  1  tablet  in  50  minims  of  water  about 
a  2  percent,  solution;  these  are  used  for  instillation  into  the 
eyes  of  newborn  infants  to  prevent  gonorrhea!  ophthalmia. 
Only  distilled  water  should  be  used  and  the  solution  protected 
from  light. 


SQUIBB'S  MATERIA  MEDICA       407 
f  Tablets  Silver  Nitrate  Compound,  Squibb 

(Gastritis) 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 


Silver  Nitrate  */4  gr- 

ELxt.  Opium  1/g  gr. 

Ext.  Nux  Vomica  !/4  gr. 

Ext.  Belladonna  Vs  gr- 
Potassium  Nitrate 


Nitrate  of  silver  is  a  power- 
ful Astringent  to  mucous 
surfaces.  It  has  been  found 
useful  in  inflamed  conditions 
of  the  stomach  and  intestines, 
as  in  gastritis,  chronic  ulcer 

and  diarrhea.  The  pain  often  produced  by  its  ingestion  is 
here  guarded  against  by  the  opium  and  belladonna  present. 
Pigmentation  of  the  skin  sometimes  follows  the  continued  use 
of  these  tablets,  as  it  does  with  silver  salts  generally.  Dose: 
1  tablet  with  water  an  hour  before  eating;  as  an  intestinal 
astringent,  1  tablet  one  or  two  hours  after  meals. 

Tablets  Soda  and  Rhubarb.  See  Tablets  Rhubarb  and  Soda. 

Tablets  Soda=Mint,  Squibb 

Per  1000  Per  500  Per  100 

C.T. 

Screw-cap  pocket  vials  per  doz., 

Sodium  Bicarbonate  43/4  gr.  1  This  is  an  agreeable  Antacid 
Ammonium  Carbonate  1/4  gr.  j-  and  gastric  stimulant,  employed 
Oil  Peppermint  q.  s.  J  in  nausea,  hyperacidity,  flat- 

ulence       and         indigestion. 

Squibb's  highly  purified  sodium  bicarbonate  is  used  in  these 
tablets,  and  they  will  be  found  more  palatable  than  similar 
preparations.  The  presence  of  ammonium  carbonate  in  the 
formula  adds  very  much  to  their  prompt  therapeutic  action, 
especially  in  cases  where  f  aintness  is  a  symptom.  Dose :  1  or  2 
tablets  repeated  as  required,  allowed  to  dissolve  in  the  mouth 
or  taken  with  a  swallow  of  water. 

Tablets  Soda=Mint  and  Pepsin,  Squibb 

Per  1000  Per  500  Per  100 

C.T. 


Sodium  Bicarbonate  4^/2  gr- 
Ammonium  Carbonate  1/4  gr. 
Pepsin  1  gr. 

Oil  Peppermint  q.  s. 


This  combination  at  times 
gives  relief  in  some  forms  of 
indigestion  where  there  is  an 
excessive  secretion  of  hydro- 


chloric acid.  In  these  cases 
the  tablets  are  administered  directly  after  meals.  Dose:  1  or  2 
tablets,  repeated  as  required. 


The  founder  of  the  House  of  Squibb,  Dr.  Edward  R.  Squibb, 
not  only  had  high  ideals,  but  lived  and  labored  for  them;  and, 
in  the  words  of  William  Miller  Bartlett,  "the  House  of  Squibb 
stands  today  as  a  living  monument  to  the  honor,  integrity,  zeal 
and  devotion  of  its  founder." 


408       SQUIBB'S  MATERIA  MEDICA 

Tablets  Sodium  Benzoate  5  gr.,  Squibb 

Per  1000  Per  500  Per  100 

C.T. 

Sodium  benzoate  is  employed  as  an  Antiseptic  and  Anti- 
rheumatic:  in  rheumatism,  cystitis,  gout,  follicular  tonsillitis, 
coryza,  etc.  Dose:  1  to  2  tablets  three  or  four  times  a  day, 
with  a  glass  of  water,  between  meals;  in  tonsillitis  and  thrush, 

1  tablet   allowed    to   dissolve   slowly   in    the   mouth   every    two 
hours. 

Tablets  Sodium  Bicarbonate  5  gr.,  Squibb 

Per  1000  Per  500  Per  100 

C.T. 

These  tablets  are  made  from  Squibb's  high  quality  sodium  bicar- 
bonate, which  is  perfectly  free  from  carbonate  and  hence  with- 
out the  bitter  taste  common  to  the  regular  market  article.  They 
are  used  for  correcting  acidity  of  the  stomach,  heartburn,  and 
allied  disturbances.  Dose:  1  or  2  tablets  after  meals,  or  as 
required,  to  be  repeated  if  necessary  in  half  an  hour. 

Tablets  Sodium  Bicarbonate  and  Bismuth.     See  Tablets 
Bismuth   and   Sodium    Bicarbonate. 

Tablets  Sodium  Bicarbonate  and  Magnesia,  Squibb 

Per  1000  Per  500  Per  100 

C.T. 

Sodium  Bicarbonate  lOgr.  )      A    favorite    Antacid    and 

Magnesia  Calcined   Light   10  gr.  j      Antizymotic,      with      mild 

laxative  action  when  given 

in  large  doses.  Dose:  1  or  2  tablets  about  two  hours  after 
meals,  or  every  three  or  four  hours  if  required. 

fTablets  Sodium  Bicarbonate  Compound,  Squibb 

(Colic  No.  2,  Infantile) 

Per  1000  Per  500  Per  100 

T.T. 

Sodium  Bicarbonate  1  gr.  1  These  tablets  are  used  in 
Paregoric  2  min.  [  fermentation,  colic  and  rest- 

Oil  Fennel  q.  s.  J       lessness     in     young     children. 

As    they    are    not    unpleasant 

to  the  taste,  children  do  not,  as  a  rule,  object  to  them.  They 
dissolve  readily  in  warm  water,  and  the  dose  may  be  easily 
regulated  to  suit  the  age  of  the  patient.  Each  tablet  contains 

2  minims  of  paregoric,   equivalent   to  1/125   grain   of   powdered 
opium.      Directions:    Dissolve   10  tablets  in    10  teaspoonfuls  of 
warm  water,  and  give   10  to  20  drops  every  ten  or  fifteen  min- 
utes until  relieved. 


SQUIBB'S  MATERIA  MEDICA       409 
Tablets  Sodium  Bromide  5  gr.,  Squibb 

C.T.  Per  1 000  Per  500  Per  100 

Sodium  bromide  is  the  salt  most  frequently  employed  in  nerve 
sedation,  as  it  is  less  unpleasant  to  the  taste  and  its  continued 
use  is  said  not  to  cause  such  marked  depression  as  the  potas- 
sium salt.  It  is  used  in  epilepsy,  mania,  and  excited  states  of  the 
nervous  system  with  loss  of  sleep  and  reflex  irritability.  Dose: 
1  or  2  tablets,  with  water,  every  hour  or  two  until  relieved. 

Tablets  Sodium  Bromide  10  gr.,  Squibb 

C.T.  Per  1000  Per  500  Per  fOO 

Dose:  1  tablet  every  hour  for  three  doses,  as  a  Hypnotic;  2  or 
more  tablets  three  times  daily  in  epilepsy. 

Tablets  Sodium  Citrate  2  gr.,  Squibb 

C.T.  Per  1000  Per  500  Per  100 

These  tablets  are  intended  for  use  in  the  modification  of  cow's 
milk  for  infant  feeding  according  to  the  method  elaborated* 
by  Drs.  A.  C.  Cotton,  Allin  and  J.  W.  Vanderslice.  The 
sodium  citrate  is  said  to  inhibit  dense  coagulation  of  the  milk 
and  thus  render  it  more  digestible.  Directions:  A  concentrated 
aqueous  solution  is  made  with  one  or  more  tablets  and  added 
to  the  bottle  of  food  at  the  time  of  feeding  in  quantities  repre- 
senting 1  to  3  grains  of  the  citrate  to  each  fluidounce  of  pure 
milk  in  the  feeding  mixture;  the  amount  varies  with  the  con- 
ditions, the  object  being  to  attain  complete  digestion  of  the 
milk  as  shown  by  the  absence  of  curds  in  the  stools. 

Tablets  Sodium  Citrate  5  gr.,  Squibb 

C.T.  Per  1000  Per  500  Per  100 

Used  the  same  as  the  preceding  tablets. 

Tablets  Sodium  Glycocholate  Compound,  Squibb 

(Dr.  A.  C.  Croftan) 

Pink=coated  (P.  C.  T.)  Per  1000       Per  500       Per  100 

Sodium  Glycocholate  1  gr.  7  Glycocholate  of  sodium  is 
Acid  Salicylic  Natural  1  gr.  j  indicated  where  the  biliary 

secretion    is    deficient.       It    is 

regarded  as  an  ideal,  true  Cholagogue,  increasing  the  secre- 
tions from  the  liver  where  the  secreting  cells  are  intact.  It 
has  been  observed  to  increase  the  flow  of  bile  to  a  very  large 
extent  and  to  be  of  value  in  cholelithiasis.  Rutherford  estab- 
lished the  cholagogue  effect  of  sodium  salicylate,  and  the  union 
of  the  two  remedies  is  here  offered  for  clinical  trial,  as  has  been 
suggested  by  Dr.  A.  C.  Croftan.  Dose:  1  tablet  before  meals, 
with  abundant  water. 


The  Squibb  Ideals  have  taken  concrete  form  in  the  Squibb 
Products;  these  are  universally  recognized  as  standards  of 
uniform  Purity  and  Efficacy,  that  is,  general  Excellence  and 
Reliability.  Specify  SQUIBB'S  when  prescribing  or  ordering. 


410        SQUIBB'S  MATERIA  MEDICA 

Tablets  Sodium  Phosphate  10  gr.,  Squibb 

C.T.  Per  1000  Per  500  Per  100 

Sodium  phosphate  acts  as  a  Saline  Cathartic.  It  is  used  mainly 
in  the  treatment  of  habitual  constipation  with  hepatic  torpor  and 
mental  hebetude.  Dose:  1  to  3  tablets  before  breakfast,  in  a 
glass  of  hot  water,  to  produce  a  natural  movement  of  the 
bowels  without  debilitating  effect.  The  sodium  phosphate  in 
these  tablets  is  free  from  arsenic  and  their  use  may  therefore  be 
continued  as  long  as  necessary  without  danger. 

Tablets  Sodium  Phosphate  Compound,  Squibb 

(Laxative,   Children's,  Dr.   E.  Chapin) 
C.T.  Per  1000  Per  500  Per  100 

Sodium  Phosph.  Dried  1  gr.  1  This  is  an  agreeable  Laxative 
Rhubarb  Powdered  VlO  gr.  I  for  young  children.  The  ac- 
Sulphur  !/5  gr.  [  tion  of  the  sodium  phosphate 

Oil  Peppermint  q.  t.  J       is    supplemented    by    rhubarb 

,  and  sulphur.     For  use  in  very 

young  children  the  tablets  are  crushed  and  mixed  with  a  little 
water  in  a  spoon.  Dose:  for  infants,  1  to  3  tablets  a  day; 
for  children  one  year  or  over,  3  tablets  three  times  a  day,  in- 
creasing or  reducing  the  dose  as  effect  is  produced. 

Tablets  Sodium  Salicylate  3  gr.,  Squibb 

C.T.  Per  1000         Per  500         Per  100 

Sodium  salicylate  is  an  Antiferment  and  Antirheumatic.  It 
increases  the  excretion  of  urea  and  uric  acid  and  corrects  gastric 
and  intestinal  fermentation.  In  acute  rheumatism  it  commonly 
allays  pain  and  fever,  reduces  the  swelling  and  inflammation  and 
prevents  cardiac  complications.  It  is  deemed  useful  also  in 
chronic  rheumatism  and  for  the  relief  of  neuralgic  and  sciatic 
pains.  Its  administration  occasionally  produces  nausea,  and  it 
should  not  be  given  during  the  process  of  digestion.  Strontium 
salicylate  is  usually  substituted  where  the  sodium  salt  disagrees 
with  the  patient.  Dose :  1  tablet  every  two  or  three  hours, 
with  water. 

Tablets  Sodium  Salicylate  5  gr.,  Squibb 

C.  T.,  Plain  or  Per  1000       Per  500       Per  100 

Wintergreen  Flavor 
Dose :     1    to  3  tablets  every  three  or  four  hours,  with  water. 

Tablets  Sodium  Salicylate  from   Natural   Acid,   5   gr., 
Squibb  Per  1000         Per  500         Per  100 

C.T. 

By  some  practitioners  sodium  salicylate  prepared  from  natural 
salicylic  acid  (so-called  "true"  salicylic  acid)  is  claimed  to  be 
better  borne  by  the  stomach  and  to  be  therapeutically  more 
active  than  that  made  from  the  synthetic  acid.  While  this  may 
be  true  when  impure  salicylic  acid  is  used  in  the  preparation 
of  the  sodium  salicylate,  it  is  extremely  doubtful  whether  the 
natural  product  offers  any  advantages  over  a  properly  made 


SQUIBB'S  MATERIA  MEDICA       411 

Tablets  Sodium  Salicylate  from  Natural  Acid,  5   gr., 
Squibb    (Cont.) 

and  pure  synthetic  preparation.  As  there  exists,  however,  a 
demand  for  this  article,  we  have  added  these  tablets  to  our 
list.  Dose :  1  to  3  tablets  every  three  or  four  hours,  with  water. 

t  Tablets  Sodium  Salicylate  and  Colchicine  Compound, 
Squibb  (Rheumatism,  Dr.  Liggett) 

C.T.  Per  1000       Per  500       Per  100 

Sodium  Salicylate  5  gr.  1      Sodium  salicylate  is  generally 

Colchicine  1/120  gr.  f      conceded    to    be    an    efficient 

Codeine  Sulphate  Vl6  gr.  J  remedy  in  articular  rheuma- 
tism, relieving  pain  and  in- 
flammation and  reducing  the  fever.  Colchicine  favors  elimi- 
nation of  effete  material,  and  frequently  aborts  an  attack.  Co- 
deine contributes  a  mild  anodyne  effect.  These  tablets  have 
been  found  efficient  in  the  treatment  of  acute  and  chronic  at- 
tacks of  rheumatism  and  gout.  Dose:  1  tablet  every  three  or 
four  hours,  with  water,  unlit  the  pain  abates  or  the  bowels 
move  freely. 

f  Tablets  Sodium  Salicylate  and  Colchicum  Compound, 
No.  2,  Squibb        (Antirheumatic   No.  3) 

C.T.  Per  1000  Per  500  Per  100 


Sodium  Salicylate        7  */2  gr- 
Wine  Colchicum  Seed 

U.S.P/90  21/2  min. 

Sodium  Bicarbonate          2  gr. 
Wintergreen  Flavor  q.  s. 


These  tablets  have  been  found 
useful  in  acute  and  chronic 
rheumatism,  arthritis,  and 
rheumatic  pharyngitis.  They 
contain  a  larger  dose  of 


sodium  salicylate  than  other 
combinations  listed,  while  the  presence  of  sodium  bicarbonate 
tends  to  lessen  gastric  irritation  and  correct  hyperacidity.  The 
addition  of  wintergreen  renders  them  more  palatable.  Dose: 
1  or  2  tablets  every  three  or  four  hours. 

Tablets  Sodium  Salicylate  Compound,  Squibb 

(Antifermenta-tive) 

C.T.  Per  1000       Per  500       Per  100 

Chocolate*coated  (C.  C.  T.) 

Sodium  Salicylate  2  gr.    }     These    tablets    are     used    for 

Ginger  Powdered  2  gr.    I     their    Carminative    and    Anti- 

Capscium  Powdered  Vio  gr.  [  zymotic  action  in  attacks  of 
Cardamom  Powdered  1/4  gr.  J  digestive  disturbance  attended 

by       flatulence,       pain       and 

diarrhea.  Dose :  in  flatulence  or  colic,  1  tablet,  in  water,  one 
to  two  hours  after  meals,  followed  by  1  at  bedtime,  if 
necessary.  In  diarrhea,  1  or  2  tablets  every  two  or  three  hours. 


The  Squibb  Label  on  a  package  is  a  positive  guaranty  for  the 
uniform  Purity  and  Reliability  of  the  product.  We  make  only 
ONE  quality:  the  SQUIBB  quality;  and  our  prices  are  as  low 
as  they  can  be  made  for  that  quality.  Specify  SQUIBB'S. 


412        SQUIBB'S  MATERIA  MEDICA 

Tablets  Sodium  Succinate  5  gr.,  Squibb 

C.T.  Per  1000          Per  500          Per  100 

Sodium  Succinate  has  latterly  come  into  vogue  as  a  Cholagogue 
and  Alterative  for  use  in  the  treatment  of  cholecystitis,  choleli- 
thiasis and  catarrhal  conditions  of  the  gall  bladder  and  bile 
duct.  Clinical  experience  seems  to  prove  that  often  under  its 
prolonged  use  paroxysms  of  biliary  colic  become  less  frequent 
and  less  intense  and  sometimes  cease  entirely.  By  virtue  of  its 
cholagogue  action,  it  tends  to  limit  the  formation  of  calculi  and 
to  aid  in  their  elimination.  Dose:  1  or  2  tablets  three  or  four 
times  a  day.  A  saline  cathartic  should  occasionally  be  given. 

f  Tablets  Sparteine  Compound,  Squibb 
(Cardiac,  Dr.  Waldstein) 

C.T.  Per  1000       Per  500       Per  100 

Sparteine  Sulphate  1/io  gr.  ~|  These  tablets  are  used  in 
Codeine  !/2Q  gr.  rapid  heart  action  with  irreg- 

Tr.  Strophanthus  >•     ular  pulse,  hurried   respiration 

U.  S.   P.   '90  3  min.         and  derangement  of  the  func- 

Caffeme  Citrated  */2  gr.  J       lions  of   the   kidneys.       Dose : 

1    tablet   every   3   or  4  hours, 
with  water. 

Tablets  Sparteine  Sulphate  1/10  gr.,  Squibb 

C.T.  Per  1000       Per  500       Per  100 

Sparteine  sulphate  is  considered  by  many  physicians  to  be  a 
useful  Heart  Tonic  and  Regulator  in  the  incompetency  of 
chronic  valvular  disease  and  in  cardiac  arhythmia;  others  em- 
ploy it  mainly  for  its  diuretic  effects  in  cases  of  cardiac  dropsy. 
It  is  believed  to  be  free  from  cumulative  action.  Dose:  1  or 
2  tablets  three  or  four  times  a  day.  (NoTE. — The  dose  of 
sparteine  sulphate  is  variable.  Some  observers  claim  to  ob- 
tain results  from  as  little  as  1/20  grain,  while  others  recom- 
mend it  to  be  given  in  2-grain  doses.  It  is  probably  best  to 
begin  with  a  small  dose,  say  1/10  grain,  and  rapidly  increase  it 
until  effective.)  ^* 

Tablets  Sparteine  Sulphate  1/4  gr.,  Squibb 

T.T.  Per  1000        Per  500        Per  100 

Dose :  I  tablet  every  three  or  four  hours,  in  irregular  heart 
action  and  in  dropsy. 

Tablets  Strontium  Salicylate  5  gr.,  Squibb 

C.T.  Per  1000       Per  500       Per  100 

Highly  recommended  by  Dr.  H.  C.  Wood  as  an  Intestinal 
Antiseptic  for  gouty  and  rheumatic  patients,  and  for  its  Anti- 
rheumatic  effect  in  all  cases  where  the  salicylates  are  indicated. 
As  an  intestinal  antiseptic,  it  is  preferred  by  Dr.  Wood  to  salol, 
naphthol,  etc.  Dose :  1  to  3  tablets  with  water  every  three  or 
four  hours;  for  fermentation  and  flatulence,  1  or  2  tablets  before 
or  immediately  after  meals. 


SQUIBB'S  MATERIA  MEDICA       413 

Tablets  Strontium  Salicylate  and  Charcoal  Compound, 
Squibb  (Corrective) 

C.T.  Per  1000       Per  500       Per  100 

Strontium  Salicylate  2  gr.  1  Strontium  Salicylate  acts  as 
Charcoal  2  gr.  an  Antizymotic  similar  to  so- 

Gingerin  Vs  8r-  f      dium    salicylate;    in    combina- 

Oleoresin  Capsicum  VlOO  gr-  *i°n  with  charcoal  and  car- 
Oil  Cloves  q.  s  J  minatives,  as  in  this  formula, 

its  value  is  increased.     These 

tablets  have  been  found  useful  in  gastric  and  intestinal  indi- 
gestion with  flatulence,  fermentation,  pain  and  diarrhea.  Dose: 
1  or  2  tablets  before  meals  or  immediately  after,  repeated  in 
two  hours  if  needed;  for  diarrhea,  1  tablet  every  two  or 
three  hours. 

^Tablets  Strophanthus  Compound,  Squibb 

T.T.  Per  1000       Per  500       Per  100 

Tr.  Strophan.  U  .S.  P.  '90  2  min.  1  The  action  of  digitalis  is 
Tr.  Digitalis  U.  S.  P.  '90  3  min.  3  here  reinforced  by  that  of 

strophanthus,    this    union, 

according  to  some  authorities,  producing  a  more  regular  action 
of  the  heart.  Strophanthus  is  said  to  act  on  the  heart  in  a 
manner  similar  to  digitalis,  but  to  be  more  rapid  and  less  per- 
sistent. The  careful  selection  of  drug  and  the  skill  with  which 
these  tablets  are  prepared  guarantee  a  prompt  and  uniform  ther- 
apeutic action.  Dose:  1  tablet  every  two  hours,  decreasing 
dose  as  the  heart  action  becomes  stronger  and  more  regular. 

*Tablets  Strophanthus  Compound  No.  2,  Squibb 

T.T.  Per  1000       Per  500       Per  100 

Tr.  Stroph.  U.S.P."90,  2  min.  1  Although  many  consider  the 
Tr.  Digit.  U.S.P.'90  2  min.  j-  combination  of  a  number  of 
Nitroglycerin  VlOO  gr«  J  heart  remedies  unscientific, 

this  formula  enjoys  consider- 
able use.  The  addition  of  nitroglycerin  lessens  arterial  ten- 
sion and  reduces  the  work  of  the  heart.  This  tablet  is  em- 
ployed where  the  cardiac  action  is  rapid,  feeble  or  irregular, 
with  pallid  countenance  and  neuralgic  pains.  Dose :  1  tablet 
three  times  a  day.  , 

Tablets  Strophanthus  Compound  No.  4,  Squibb 

T.T.  Per  1000       Per  500       Per  100 

Tr.  Stroph.  U.S.P.'90  2  min.  "I  Although  objection  has  been 
Tr.  Digit.  U.S.P.'90  2  min.  >  made  on  scientific  grounds  to 
Strychnine  Sulphate  1/ioo  g""-  J  combining  several  heart  drugs 

in  one  mixture,  this  formula  is 

a  favorite  with  many  physicians.  It  is  a  modification  of  our 
Tablets  Strophanthus  Compound,  the  difference  consisting  in 
the  addition  of  VlOO  grain  of  strychnine  sulphate.  Dose:  1 
tablet  three  or  four  times  daily. 

Squibb's  Tablets  are  made  from  the  Squibb  quality  of  ingredients 
and  by  improved  processes  that  insure  accurate  dosage  and 
rapid  and  complete  disintegration  or  solution  in  the  system, 
hence  prompt  and  full  therapeutic  effect.  Specify  SQUIBB'S. 


414  •     SQUIBB'S  MATERIA  MEDICA 

Tablets  Strophanthus  and  Digitalis  Compound.  See  Tab- 
lets Digitalis  and  Strophanthus  Compound. 

Tablets  Strychnine,   Digitalis  and  Nitroglycerin.      See 

Tablets  Nitroglycerin,  Digitalis  and  Strychnine. 

Tablets  Strychnine  and  Ipecac  Compound,  Squibb 

(Anorexia  No.  2;   Dyspeptic,  Dr.  E.  Haworth.) 
Chocolate-coated  (C.  C.  T.)  Per  1000      Per  500      Per  100 
Strychnine  Sulphate      !/40  gr.  ]      This     combination     has     been 
Ipecac  !/8  gr.  I       used    in   certain   conditions   of 

Rhubarb  1/4  gr.  f      the    system    where    the    desire 

Capsicum  !/8  8r-  J       f°r     food     is    below     normal, 

and  where  digestion  is  faulty. 

It  represents  a  combination  of  digestive  stimulants  and  tonics, 
which,  by  increasing  the  secretion  from  the  salivary  and  peptic 
glands,  promote  the  elaboration  and  elimination  of  the  contents 
of  the  stomach,  with  consequent  returning  appetite.  Dose:  1 
tablet  before  or  immediately  after  meals,  repeated  in  an  hour 
if  necessary. 

Tablets  Strychnine,  Iron  and  Arsenic.     See  Tablets  Iron, 
Arsenic   and   Strychnine. 

*Tablets  Strychnine  Nitrate  1/60  gr.,  Squibb 

T.T.  Per  1000       Per  500       Per  100 

C.  C.  T.  or  P.  C.  T. 

Strychnine  strengthens  the  action  of  the  heart,  excites  the  flow 
of  the  gastric  juice,  stimulates  the  peristaltic  action  of  the  in- 
testines and  is  deemed  a  good  tonic  in  atonic  conditions  of  the 
system.  It  stimulates  the  motor  and  vasomotor  centers  of  the 
cord;  according  to  Ringer,  it  lessens  resistance  of  the  cord  and 
increases  the  diffusibility  of  impressions.  It  is  used  in  muscular 
atrophy,  neuritis,  gastralgia,  atonic  dyspepsia,  as  a  heart  tonic, 
in  neuralgic  affections,  in  combating  chronic  alcoholism,  and  as 
a  general  tonic  in  anemia  and  debility.  Dose :  1  tablet  after 
meals  in  dyspepsia  and  as  a  general  tonic. 

*Tablets  Strychnine  Nitrate  1/50  gr.,  Squibb 

Per  1000       Per  500       Per  100 
T.T. 

C.  C.  T.  or  P.  C.  T. 

Dose:  1  tablet  three  times  a  day  as  a  Stomachic  Tonic  in  dys- 
pepsia; 1  tablet  every  three  or  four  hours  in  the  treatment  of  the 
alcohol  habit,  and  as  a  general  Tonic  and  Aphrodisiac. 

Tablets  Strychnine  Nitrate  1/40  gr.,  Squibb 

Per  1000        Per  500        Per  100 
T.T. 

C.  C.  T.  or  P.  C.  T. 
Dose :      1    tablet  after  eating,  with  a  swallow  of  water. 


SQUIBB'S  MATERIA  MEDICA       415 

Tablets  Strychnine  Nitrate  1/30  gr.,  Squibb 

T.T.  Per  1000       Per  500       Per  100 

C.  C.  T.  or  P.  C.  T. 

Dose:  1  tablet  every  four  hours,  in  atonic  conditions  of  the 
bladder;  I  tablet  after  meals  in  dyspepsia  with  anorexia  and 
gastralgia;  in  alcoholism,  1  •tablet  every  four  hours  in  combina- 
tion with  other  tonics.  (See  also  Tablets  Gold  and  Sodium 
Chloride  Compound,  Squibb.) 

Tablets  Strychnine,  Quinine  and  Iron.    See  Tablets  Iron, 
Quinine  and  Strychnine. 

Tablets  Strychnine  Sulphate  1/100  gr.,  Squibb 

T.T.  Per  1000       Per  500       Per  100 

C.  C.  T.  or  P.  C.  T. 

Dose :     As  a  general  Tonic,  1   tablet  three  times  a  day,  directly 

after  meals. 

Tablets  Strychnine  Sulphate  1/60  gr.,  Squibb 

T.T.  Per  1000       Per  500       Per  100 

C.  C.  T.,  R.  C.  T.  or  P.  C.  T. 

Dose:      1    tablet   after   each   meal,   as   a  Digestive   and   general 

Nerve  Tonic. 

Tablets  Strychnine  Sulphate   1/50  gr.,  Squibb 

T.T.  Per  1000       Per  500       Per  100 

C.  C.  T.  or  P.  C.  T. 

Dose :  I  tablet  after  meals  and  at  bedtime  as  a  Nerve  and  Gas- 
tric Stimulant. 

Tablets  Strychnine  Sulphate   1/40  gr.,  Squibb 

T.T.  Per  1000        Per  500        Per  100 

C.  C.  T.,  R.  C:  T.  or  P.  C.  T. 

Dose :  1  tablet  after  meals  as  a  Cardiac  and  General  Tonic 
and  as  a  Digestive  Stimulant. 

Tablets  Strychnine  Sulphate  1/30  gr.,  Squibb 

T.T.  Per  1000       Per  500       Per  100 

C.  C.  T.,  R.  C.  T.  or  P.  C.  T. 

Dose :  1  tablet  after  meals  and  at  bedtime  as  a  Cardiac  and 
General  Tonic,  Aphrodisiac,  and  Digestive  Stimulant. 

Tablets  Strychnine  Sulphate  1/20  gr.,  Squibb 

T.T.  Per  1000       Per  500       Per  100 

C.  C.  T. 
Dose:    I  tablet  after  meals  as  a  Nerve  Tonic. 

f 

This  house  supplies  only  one  quality  of  each  product:  that  best 
suited  to  the  purposes  intended.  The  specification  Squibb's" 
is  not  open  to  various  interpretations;  it  has  a  plain,  posi- 
tive meaning.  Therefore,  when  prescribing,  specify  SQUIBB'S. 


416        SQUIBB'S  MATERIA  MEDICA 

Tablets  Sulphocarbolates  Combined,  Squibb 

C.T.  Per  1000       Per  500       Per  100 

Zinc  Sulphocarb.  '  1 1/2  gr.  1  These  tablets  are  used  as  an 
Sodium  Sulphocarb.  l*/28r*f  Astringent  and  Antiseptic  in 
Calcium  Sulphocarb.  l^/28r>J  intestinal  fermentation,  typhoid 

and  tuberculous  diarrhea,  in- 
testinal catarrh,  etc.  Dose :  1  tablet,  with  water,  before  meals, 
repeated  in  two  hours  if  necessary. 

Tablets   Sulphonethylmethane  5   gr.,  Squibb 

(Trional)  Per  1000         Per  500         Per  100 

C.T. 

For  sleeplessness  caused  by  mental  excitement  or  worry,  where 
pain  is  not  a  symptom,  trional  is  considered"1  a  safe  and  reliable 
hypnotic,  reported  to  be  noncumulative  and  usually  free  from 
bad  after-effects,  except  where  constipation  exists,  which  con- 
dition is  overcome  by  the  use  of  alkaline  mineral  waters.  Dose: 
I  tablet  every  hour  for  three  doses  before  retiring;  or  3  at  a 
dose,  taken  in  soup,  beef  tea,  hot  milk  or  water. 

Tablets  Sulphonethylmethane  5  gr.,  Squibb 

(Trional)  Per   1000         Per  500         Per   100 

C.T. 

Hypnotic.  Dose :  1  tablet  every  hour  for  three  doses  before 
retiring,  or  3  tablets  at  one  dose  at  bedtime,  taken  in  hot  tea, 
beef  tea  or  hot  milk.  During  its  continued  use,  as  with  Tablets 
Sulphonmethane,  it  is  advised  to  give  alkaline  waters  freely 
and  to  avoid  constipation. 

Tablets  Sulphonmethane  5  gr.,  Squibb 

(Sulphonal)  Per  1000         Per  500         Per  100 

C.T. 

Hypnotic,  in  simple  insomnia  and  in  sleeplessness  present  in 
mental  diseases  attended  with  excitement  and  delirium;  also  a 
Sedative  in  neuroses  with  a  spasmodic  element.  Dose :  1  tablet 
every  hour  for  three  doses  before  retiring,  or  3  or  4  tablets  at 
one  dose  with  a  hot  drink  on  retiring. 

Tablets  Sulphur  Compound,  Squibb 

Per  1000        Per  500        Per  100 
C.T. 
Chocolate*coated  (C.  C.  T.) 


Sulphur  5  gr. 

Cream  Tartar  1  gr. 

Ext.  Ipecac  Vino  gr- 

Ext.  Capsicum  Vsoo  gi^ 

Acid  Arsenous  VlOOO  gr- 

Calcium   Sulphide  i/8  gr- 


These  tablets  are  used  in  the 
treatment  of  boils,  acne  and 
pimples,  with  indigestion  and 
constipation;  also  in  pityriasis 
and  chronic  eczema.  Dose : 
I  tablet  three  times  a  day,  af- 
ter meals  and  at  bedtime. 


SQUIBB'S  MATERIA  MEDICA       417 

Tablets  Sutnbul,  Camphor  and  Hyoscyamus  Compound. 

See  Tablets  Camphor,  Hyoscyamus  and  Sumbul  Compound. 

Tablets   Sumbul   Compound,   Squibb 

(Dr.  Goodell)  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 

Extract  Sumbul  1  gr. "]       These    tablets    possess    Hema- 

Iron  Sulphate  Dried  1  gr.  I  tinic  and  Antispasmodic  prop- 
Asafetida  2  gr.  f  erties.  They  appear  to  give 

Acid  Arsenous  V40  gr.  J      best  results  in  anemic  patients 

with     nervous     or     hysterical 

symptoms.  The  flatulence  and  distress  after  eating  which  us- 
ually cause  so  much  disturbance  in  this  class  of  patients  are  as 
a  rule  also  corrected.  The  asafetida  used  in  these  tablets  is 
of  the  highest  quality,  while  its  disagreeable  odor  and  taste  are 
completely  masked  by  the  very  soluble  coating.  Dose:  1  or  2 
tablets  after  meals  and  at  bedtime. 

fTablets  Sumbul  Compound  No.  2,  Squibb 

(Hysteria)  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 


Extract  Sumbul  1  gr. 

Iron  Sulphate  Dried  1  gr. 

Asafetida  2  gr. 

Acid  Arsenous  VlOO  8r- 

Apomorphine  Hydrochlor.  VoO  gr- 


The  nervous  manifesta- 
tions grouped  under  the 
title  of  hysteria  are  fre- 
quently relieved  and  their 
further  development  ar- 


rested by  the  use  of  this 
combination  of  tonics  and  antispasmodics.  Asafetida  and  sum- 
bul  have  been  found  useful  in  spasmodic  conditions,  the  former 
relieving  the  tympanites  and  colic.  Ringer  mentions  the  useful- 
ness of  apomorphine  hydrochloride  in  hysteria;  iron  and  arsenic, 
by  improving  the  condition  of  the  patient,  tend  to  remove  the 
cause  and  often  prevent  recurrent  attacks.  Dose :  1  tablet 
hourly  for  three  or  four  doses,  with  a  glass  of  water. 

Tablets,  Sun  Cholera.  See  Tablets  Opium   and  Camphor 

Compound. 

Tablets,  Syphilis.     See  Tablets  Potassium  Iodide  and  Mercury. 

Tablets  Tannic  Acid  and  Zinc  Sulphate  Compound. 

See   Tablets   Zinc  Sulphate   and   Tannic   Acid   Compound. 

Tablets  Terpin  Hydrate  3  gr.,  Squibb 

Per  1000       Per  500       Per  100 
C.T. 

Terpin  hydrate  is  considered  a  valuable  Antiseptic  Expectorant, 
free  from  disagreeable  taste,  not  readily  disturbing  digestion,  and 
in  proper  doses  not  causing  constitutional  disturbances.  Three 
to  five  grains  repeated  every  three  or  four  hours  produce  in- 
creased secretion  of  bronchial  mucus  and  facilitate  expectoration. 
Terpin  hydrate  is  insoluble  in  water,  and  unless  tablets  made 
from  it  disintegrate  quickly  in  the  stomach  its  efficiency  is  les- 

B 


418        SQUIBB'S  MATERIA  MEDICA 

Tablets  Terpin  Hydrate  3  gr.,  Squibb  (Cont.) 

sened  or  altogether  destroyed.  Tablets  Terpin  Hydrate  Squibb 
break  up  at  once  in  the  system,  as  may  be  readily  proved  by 
dropping  a  tablet  into  water,  or  holding  one  on  the  tongue  for  a 
few  minutes.  Dose :  1  tablet  every  three  hours  with  water. 

Tablets  Terpin  Hydrate  5  gr.,  Squibb 

C.T.  Per  1000       Per  500       Per  100 

Dose:      I    tablet  every  three  or  four  hours,  with  water. 

Tablets    Terpin     Hydrate     and     Creosote     Compound, 
Squibb  Per  1000      Per  500       Per  100 

C.T. 

Chocolate-coated  (C.  C.  T.) 

Terpin    Hydrate  2  gr.    )     This    formula   has  won    favor 

Creosote  1  min.    I     in    the    treatment    of    tubercu- 

Strychnine  Sulph.  1/eo  gr.  [  losis.  It  is  said  to  arrest 
Eucalyptol  1/2  min.  J  morbid  pathological  changes 

in    the    alimentary    canal    and 

thus  allow  digestion  to  proceed  in  a  natural  way,  with  an  im- 
provement in  nutrition  and  increased  resistance  to  the  infection. 
Dose :  1  or  2  tablets  after  meals  with  water. 

f  Tablets    Terpin    Hydrate    and    Creosote    Compound 
No.  2,  Squibb  Per  1000       Per  500       Per  100 

C.T. 
Chocolate-coated  (C.  C.  T.) 


Terpin  Hydrate  2  grs. 

Creosote  1  min. 

Diacetylmorphine    Hydro- 
chloride  1/4s  gr. 
Strychnine    Sulph.  I/HO  gr. 
Eucalyptol                        1/0  min. 
Iron  Carbonate  Sacch.        1  gr. 


This  formula  is  a  modifica- 
tion of  the  preceding  one,  to 
which  an  iron  tonic  and  a 
cough  sedative  have  been 
added.  Dose :  1  or  2  tablets 
every  three  or  four  hours. 
NOTE. — These  tablets  should 


be    used    cautiously    and    the 
possible  formation  of  the  morphine  habit  guarded  against. 

•{•Tablets  Terpin  Hydrate  and  Heroin,  Squibb 

C.T.  Per  1000       Per  500       Per  100 

Terpin  Hydrate  2J/2  gr.  "1      This   formula  is  used   to  con- 

Diacetylmorphine  >     trol      cough      in      acute      and 

(Heroin)  1/50  gr.  J      chronic  bronchitis,   pneumonia, 

grip     and     phthisis.       Terpin 

hydrate  is  a  stimulating  expectorant,  with  antiseptic  properties. 
In  moderate  doses  it  causes  increased  secretion  of  bronchial 
mucus,  facilitates  expectoration,  and  may  be  continued  without 
interfering  with  the  appetite  or  digestion.  Diacetylmorphine 
serves  to  allay  cough,  deepen  respiration  and  quiet  the 
pulse.  Dose :  1  or  2  tablets  every  two  or  three  hours  until  the 
cough  is  quieted,  then  at  longer  intervals.  NOTE. — These  tab- 
lets should  be  used  cautiously  and  the  possible  formation  of 
the  morphine  habit  guarded  against. 


SQUIBB'S  MATERIA  MEDICA       419 

•{•Tablets     Terpin     Hydrate     and     Heroin     Compound, 
Squibb        (Cough   Sedative,   Dr.   F.  W.   Shaw) 

C.T.  Per  1000       Per  500       Per  100 

Terpin  Hydrate  2*/2  gr.  1      This      combination      is 

Diacetylmorph.  (Heroin)  1/so  gr.  I  found  useful  in  cough 
Pilocarpine  Hydrochloride  VlOO  gr-  [  with  irritated  throat 
Potassium  Dichromate  ^200  gr-  J  a°d  painful  expectora- 

tion.    Dose:     1    tablet 

every  two  or  three  hours  until  the  cough  abates,  then  at  longer  in- 
tervals. NOTE. — These  tablets  should  be  used  cautiously  and 
the  possible  formation  of  the  morphine  habit  guarded  against. 

Tablets  Three  Iodides,  Squibb 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 

Mercury  Iodide  Red  Vso  gr- 1  Cutaneous  diseases  of  a  scaly 
Arsenic  Iodide  1/40  §r-  f  nature,  chronic  rheumatism 

Iron  Iodide  1/12  8r-  J       an<^  tertiary  syphilis  are  indi- 

cations   for    the    use    of    this 

formula.  It  represents  three  of  the  most  powerful  alteratives, 
which  act  upon  the  blood  and  absorbent  system,  increase  elim- 
ination of  waste  products,  and  by  overcoming  the  impoverished 
state  of  the  blood,  tend  to  bring  about  a  restoration  of  health. 
Dose:  1  tablet,  with  water,  three  or  four  times  a  day. 

Tablets  Three  Valerates,  Squibb 

(Three    Valerianates)  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 

Iron  Valerate  1  gr.  1       For   the   relief  of  the  nervous 

Quinine  Valerate  1  gr.  >      symptoms      usually      seen      in 

,         Zinc  Valerate  1  gr.  J       hysterical    subjects,    these    tab- 

lets     are      often      used      with 

decided  beneficial  results.  They  act  as  an  Antispasmodic,  Ner- 
vine and  Tonic.  The  disagreeable  odor  of  the  ingredients  is  well 
masked  by  the  coating,  and  patients  as  a  rule  do  not  object  to 
their  administration.  Dose:  1  or  2  tablets  after  meals,  with  water. 

Tablets,    Throat    (Dr.   Quinlan).     See   Tablets  Acid    Benzoic 
and  Belladonna  Compound. 

Tablets  Thyroid  Gland  2  gr.,  Squibb 

C.T.  Per  1000      Per  500      Per  100 

These  tablets  are  prepared  from  the  thyroid  glands  of  sheep, 
freed  from  fat,  carefully  cleaned  and  dried  at  low  temperature. 
Each  tablet  represents  10  grains  of  the  fresh  gland  in  the  state 
of  full  therapeutic  activity.  Thyroid  glands  have  been  used  as 
an  Alterative,  Hemostatic  and  Antifat,  in  myxedema,  obesity, 
struma,  obstinate  hemorrhage  and  cretinism.  Dose :  1  tablet 
3  times  a  day,  gradually  increased  in  accordance  with  the 
tolerance  of  the  patient. 

The  prices  of  the  Squibb  Products  are  in  aH  instances  as  low  as 
the  quality  and  quantity  of  ingredients  and  the  expense  of  man- 
ufacture allow.  They  include  containers,  packing  and  boxing.  When 
ordering  or  prescribing  medicinal  products,  specify  SQUIBB'S. 


420       SQUIBB'S  MATERIA  MEDICA 

Tablets  Thyroid  Gland  5  gr.,  Squibb 

C.T.  Per  1000         Per  500         Per  100 

Dose :  1  tablet  3  times  a  day,  gradually  increased  and  adapted 
to  the  tolerance  of  the  patient. 

Tablets  Tincture  Nux  Vomica  1  min.,  Squibb 

T.T.  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 

For  indications  and  uses,  see  Tablets  Nux  Vomica  Extract 
!/4  gr.  One  minim  of  tincture  nux  vomica  corresponds  in 
strength  to  1/(;4  grain  of  extract  nux  vomica.  Dose :  1  or  2  tab- 
lets after  meals. 

Tablets  Tincture  Nux  Vomica  5  min.,  Squibb 

T.T.  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 

Five  minims  of  tincture  nux  vomica  corresponds  in  strength  to 
Vl2  grain  of  extract  nux  vomica.  Dose:  1  tablet  after  meals. 

Tablets  Tincture  Warburg's.      See  Tablets  Warburg's  Tinc- 
ture. 

Tablets,    Tonic,    Aiken's.      See    Tablets    Quinine    and    Iron 
Compound. 

Tablets,  Tonic,  Bitter.      See  Tablets  Nux  and  Ipecac  Comp. 

Tablets,  Tonic,  Children's.     See  Tablets  Blaud's  Pills  Com- 
pound No.  4. 

Tablets,    Tonic    Laxative,    Blaud's.     See   Tablets    Blaud's 
Mass  and  Aloin. 

Tablets,  Tonic,  Uterine.  See  Tablets  Ergot  and  Hydrastine. 
Tablets,  Tonsillitis.  See  Tablets  Aconite  and  Mercury  Comp. 
Tablets  Trional.  See  Tablets  Sulphonethylmethane. 

Tablets  Triple  Arsenates,  Squibb 

(Dr.   G.   H.   Hill)  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 

Iron  Arsenate  1/3o  gr-  ]       These   tablets   have  been   used 

Quinine  Arsenate  1/ao  ir-  f  with  reputed  success  in  ob- 
Strychnine  Arsenate  l/oo  gr.  J  stinate  malarial  affections, 

anemia  and  general  debili- 
tated conditions.  They  possess  Tonic  and  Alterative  properties, 
and  by  their  action  upon  the  blood  and  nutrition  have  been 
shown  to  overcome  the  depraved  state  of  the  system.  By 
thorough  trituration  accurate  dosage  is  assured;  and  as  the 
tablets  are  prepared  so  that  they  rapidly  disintegrate  in  the 
stomach,  prompt  and  uniform  therapeutic  effects  may  con- 
fidently be  expected.  Dose :  1  tablet  with  water  after  meals. 


SQUIBB'S  MATERIA  MEDICA       421 

Tablets  Triple  Bromides,  Squibb 

C.T.  Per  1000       Per  500      Per  100 

Sodium  Bromide  21/2  gr. ")  The  bromides  are  employed 
Potassium  Bromide  2*/2  gr.  f  in  nervous  excitement  due  to 
Ammonium  Bromide  2*/2  gr.  J  nerve  irritation,  but  not  when 

caused     by     derangement     of 

nerve  function  due  to  exhaustion.  This  tablet  is  employed  in 
wakefulness  and  nervous  conditions  from  overwork  or  worry, 
hysteria,  chorea,  epilepsy,  tetanus,  nausea,  seasickness,  and  as  a 
Nerve  Sedative  generally.  Dose :  1  to  4  tablets,  dissolved  in 
water,  every  three  hours  until  effective. 

Tablets  Triple  Bromides  No.  2,  Squibb 

C.T.  Per  1000       Per  500       Per  100 

Sodium   Bromide  5  gr.  "I       These    tablets    are    just    twice 

Potassium    Bromide          5  gr.  [      the  strength  of   the  preceding. 
Ammonium   Bromide        5  gr.  J       Dose :      1     or    2    tablets,    dis- 
solved in  water,  three  or  four 
times  daily,  as  a  Nerve  Sedative  in  epilepsy,  etc. 

Tablets  Triple  Bromides  Effervescent,  Squibb 

C.T.  Bottle  of  25,          ;  bottle  of  100, 

Ammonium  Bromide  3  gr.  1  This  formula  represents  a 
Sodium  Bromide  6  gr.  >  pleasant,  effervescent  combina- 

Potassium   Bromide          6  gr.  J       lion    of    the    three    commonly 

prescribed   bromides,    twice  the 

strength  of  the  regular  formula.  Dose :  1  or  2  tablets  with 
water,  taken  while  effervescing,  three  or  four  times  a  day.  Keep 
the  bottle  well  corked  and  in  a  dry  place,  and  dispense  the 
tablets  only  in  bottles. 

Tablets    Triple    Bromides    and    Cannabis    Compound, 
Squibb  (Sedative) 

C.T.  Per  1000       Per  500       Per  100 


Sodium  Bromide  2^/2  gr. 

Potassium   Bromide  21J2  gr- 

Ammonium  Bromide  21/0  gr. 
Tr.  Cannabis  U.S.P.  '90  5~min 
Tincture  Hyoscyamus  5  min. 


Where  the  use  of  the  bro- 
mides must  be  continued  for 
any  length  of  time  this  com- 
bination is  said  to  exert  a  bet- 
ter sedative  effect  and  cause 


less  systemic  disturbance  than 
the  individual  doses  of  the  separate  salts.  Tolerance  is  still 
further  assisted  by  the  modifying  action  of  the  hyoscyamus  and 
the  cannabis.  These  tablets,  are  used  in  excited  and  irritable 
states  of  the  nervous  system,  in  wakefulness  caused  by  over- 
work or  worry,  in  hysteria,  epilepsy,  delirium,  and  to  control 
seminal  emissions  and  sexual  excitement  generally.  Dispense  in 
glass.  Dose :  1  tablet  every  half  hour  or  hour  for  three  or  four 
doses,  dissolved  in  water. 


If  difficulty  is  experienced  in  procuring  any  Squibb  product, 
in  the  original  packages  here  listed,  please  notify  us;  we 
shall  see  that  your  wants  are  met  promptly  and  satisfactorily. 


422        SQUIBB'S  MATERIA  MEDICA 

Tablets  Triple  Bromides  and  Hyoscyamus  Compound, 
Squibb      (Triple  Bromides   and   Physostigma  Comp.;    Epilep- 
tic, Dr.  Batton)  Per  1000     Per  500     Per  100 
C.  T. 


Sodium  Bromide  3  gr. 

Ammonium    Bromide          3  gr. 
Potassium    Bromide  3  gr. 

Extract  Hyoscyamus         J/2  gr. 
Tincture  Physostigma  2J/2  min. 


Used  mainly  in  epilepsy  with 
reputed  success.  Dose  :  2  tab- 
lets three  times  a  day,  with 
water.  Dispense  in  glass. 


Tablets  Triplex.     See  Tablets  Aloes,  Mercury  and   Podophyl- 
lin. 

fTablets,  Tully's,  2  1/2  gr.,  Squibb 

Per  1000       Per  500       Per  100 
T.T. 

Morphine  Sulphate  3/go  S*.  1  These  tablets  represent  the 
Camphor  Powdered  4/s  gr.  j  active  ingredients  of  Tully's 

Powder     (Powder     Morphine 

Compound),  part  of  the  licorice  root  and  all  of  the  chalk  being 
omitted,  however.  They  are  used  for  their  Diaphoretic  and 
Soporific  effects  in  the  early  stages  of  bronchial  attacks,  similarly 
to  Dover's  Powder,  the  therapeutic  action  of  the  two  prepara- 
tions being  alike.  Dose:  1  tablet  every  two  or  three  hours  until 
relieved;  or  4  tablets  at  bedtime,  with  a  hot  drink. 

Tablets  Urease,  0.1  Qm.,  Squibb  Per  100 

For  the  rapid  estimation  of  urea  in  urine,  blood,  etc.  (See 
Urease  [Part  I]).  Write  for  complete  literature. 

Tablets,  Uterine  Tonic.      See  Tablets  Ergot  and  Hydrastine. 

Tablets,  Vaginal  Astringent.     See  Tablets  Zinc  Sulphate  and 
Tannic  Acid  Compound. 

Tablets   Valerates,   Three.         See  Tablets  Three  Valerates. 

Tablets  Viburnum  Compound,  Squibb 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 


Ext.  Viburnum  Prunifol.  1  gr. 
Ext.  Viburnum  Opulus  1  gr. 
Ext.  Aletris  Farinosa  1/o  gr. 
Ext.  Helonias  Dioica  !/o  gr. 
Ext.  Mitchella  Repens  */2  gr. 
Calophyllin  */4  gr. 


A  combination  of  several 
drugs,  believed  to  act  as  a 
tonic  to  the  uterine  organs,  al- 
lay inflammation  and  pain  and 
relieve  congestion.  In  pain- 
ful menstruation  and  where 


the  flow  is  scanty  or  too  pro- 
fuse they  are  said  to  be  of  benefit  Dose:  1  or  2  tablets  every 
two  or  three  hours  with  a  swallow  of  hot  tea,  beginning  the 
treatment  several  days  before  the  expected  period. 


SQUIBB'S  MATERIA  MEDICA       423 
Tablets  Viburnum  Compound  No.  2,  Squibb 

(Endometritis) 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 


Ext.  Viburnum  Prunifol.  2  gr. 
Ext.  Hamamelis  1  gr. 

Ext.  Ergot  !/2  gr. 

Ext.  Nux  Vomica         Vl2  gr. 
Hydrastin 


This  formula  is  used  in  re- 
laxed and  painful  conditions 
of  the  uterine  organs;  in  en- 
dometritis,  alone  or  in  con- 
junction with  topical  applica- 
tions; in  dysmenorrhea  and 

metrorrhagia.  The  extracts  in  this  formula  are  carefully  pre- 
pared at  our  own  laboratories,  and  are  incorporated  into 
tablets  without  heat,  so  that  none  of  their  therapeutic  properties 
are  destroyed.  Dose:  1  tablet  3  or  4  times  a  day. 

Tablets  Warburg's  Tincture,  Squibb 

(With  Aloes)  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 

These  tablets  are  prepared  by  careful  evaporation  of  Warburg's 
Tincture  at  low  temperature,  and  possess  the  full  therapeutic 
activity  of  the  preparation.  Each  tablet  represents  one  tea- 
spoonful  of  the  tincture.  They  have  been  used  in  malarial  dis- 
orders with  much  benefit,  but  at  times  under  their  continued  ad- 
ministration the  laxative  effect  may  be  too  great.  Dose :  1  or  2 
tablets  3  or  4  times  a  day,  decreasing  the  dose  or  alternating 
with  Tablets  Warburg's  Tincture  without  aloes  if  the  bowels 
move  too  freely. 

Tablets  Warburg's  Tincture  without  Aloes,  Squibb 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 

Warburg's  Tincture  is  often  effective  in  chronic  malarial  con- 
ditions, where  the  usual  remedies  are  of  no  avail.  The  tincture 
used  in  these  tablets  is  carefully  evaporated  at  low  temperature, 
so  that  none  of  the  volatile  ingredients  are  lost.  The  tablets 
represent  the  full  potency  of  the  formula  in  an  active  and  sol- 
uble form.  Dose:  1  or  2  tablets  three  times  a  day,  after  meals, 
preceding  the  treatment  by  an  active  cathartic. 

Tablets  Warburg's  Tincture  Improved,  Squibb 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 

Warburg's  Tincture  "I       The      addition      of      arsenous 

(without   aloes)         1    fl.dr.  \      acid    to    Warburg's    Tincture 

Acid  Arsenous  VlOO  gr-  J       serves    to    greatly    improve    its 

Antimalarial     effect.       Dose: 
1   or  2  tablets  three  times  a  day,  after  meals. 

Tablets  Wash  Astringent.      See    Tablets    Lead     and    Zinc 
Compound. 

The  Squibb  products  are  recognized  everywhere  as  the  Quality 
Standard.  They  are  of  uniform  purity  and  strength,  hence 
therapeutically  dependable.  When  ordering  or  prescribing  med- 
icinal products,  you  will  do  well  always  to  specify  SQUIBB'S. 


424        SQUIBB'S  MATERIA  MEDICA 

Tablets     Whooping-Cough.     See     Tablets     Antipyrine     and 
Heroin  Compound. 

Tablets  Witch  Hazel  and  Helonias  Compound.          See 

Tablets  Helonias  and  Witch  Hazel  Compound. 

Tablets     Zinc    Phosphide    and     Cannabis    Compound, 
Squibb  (Neuralgic,   Dr.   Kenyon) 

T.T.  Per  1000       Per  500       Per  100 

Chocolate-coated  (C.  C.  T.) 

Zinc   Phosphide  i/16  gr.  ]      These  tablets  are  employed  in 

Extract  Cannabis  */8  gr.         pains   caused   by   derangement 

Strychnine  Sulphate  1/eo  gr.  r  of  nerve  functions.  In  neu- 
Sodium  Arsenite  1/20  gr.  ralgias,  sciatica,  and  spas- 

Aconitine  1/400  gr-  J       modic    pains    generally,    they 

lessen     nerve     irritability    and 

excitement,  and,  by  improving  the  nutrition  of  the  nerves,  tend 
to  prevent  a  recurrence  of  the  neuralgic  attacks.  Dose :  1  tablet 
every  two  hours  for  three  doses,  then  every  three  or  four  hours. 

Tablets    Zinc   Phosphide,    Cannabis   and    Nux,   Squibb 

(Nerve  Tonic  No.  5) 

Per  1000       Per  500       Per  100 
Chocolate-coated  (C.  C.  T.) 

Zinc   Phosphide  1/g  gr.  1      The  action  of  these   tablets  is 

Extract  Cannabis  */8  gr.  r      that    of    a    Nerve    Tonic    and 

Ext.  Nux  Vomica  */8  gr-  J      Stimulant.       They     are     used 

mainly      to     control      nervous 
irritability.     Dose :    1   tablet  with  water  after  meals. 

Tablets  Zinc  Sulphate  1  gr.,  Squibb 

C.T.  Per  1000  Per  500  Per  100 

These  tablets  contain  only  the  Squibb  quality  of  pure  zinc 
sulphate,  hence  dissolve  freely  and  yield  a  clear  solution  in 
distilled  water.  They  are  intended  for  the  convenient  prepara- 
tion of  astringent  solutions.  Directions :  Dissolve  1  to  3  tablets 
in  1  fluidounce  distilled  water,  for  use  as  a  collyrium,  injection 
or  local  astringent  application. 

Tablets    Zinc    Sulphate    and    Tannic    Acid    Compound, 
Squibb  (Vaginal  Astringent) 

C.T.  Per  500  Per  100 


Zinc  Sulphate  2  gr. 

Acid  Tannic  2  gr. 

Alum  3  gr. 

Acid  Boric  6  gr. 

FI.  Gold.  Seal,  Colorl.  I  min. 


For  preparing  vaginal  douches 
that  are  used  as  an  Astringent 
and  Tonic  to  the  vaginal 
mucous  membrane,  arrest  dis- 
charge, and  lessen  inflamma- 


tion. These  tablets  dissolve 
quickly  in  water  and  are  very  convenient.  They  are  said  to 
restore  tonicity,  remove  foul  odors,  lessen  discharge  and  to  be 
useful  also  in  septic  conditions  and  relaxed  states  of  the  mucous 
membrane.  Directions:  1  or  more  tablets,  depending  upon  the 
symptoms,  are  dissolved  in  a  quart  of  hot  water  and  employed 
as  a  vaginal  douche. 


SQUIBB'S  MATERIA  MEDICA       425 

Tablets  Zinc  Sulphocarbolate  2  gr.,  Squibb 

C.T.  Per  1000  Per  500  Per  100 

This  formula  is  used  for  its  Astringent  and  Antiseptic  effect 
in  intestinal  catarrh  attended  with  flatulence,  fermentation  and 
inflammation.  In  typhoid  fever,  enteritis,  tuberculous  diarrhea 
and  dysentery  it  is  also  said  to  act  well.  Dose:  1  tablet  every 
two  hours  with  water. 


*  Tablets,    Zinc    Sulphocarbolate    and    Calomel 
pound,  Squibb 

(Cholera  Infantum,   Dr.  Fenwick) 
T.T.  Per  1000  Per  500  Per  100 


Zinc  Sulphocarb.  1/20  gr. 

Calomel  1/eo  gr. 

Salol  l/io  gr. 

Bismuth  Subnitrate  1/2  gr. 

Pepsin  1/4  gr. 


In  the  treatment  of  fermenta- 
tive diarrhea  in  children,  this 
formula  has  proved  very 
fective,  acting  as  an  Anti- 


septic, Sedative  and  Astrin- 
gent. Dose:  for  infants  six 
months  to  one  year  old,  1  tablet  every  ten  minutes  for  the 
first  hour,  then  every*  half  hour  or  hour  until  relieved. 

Tablets  Zinc  Sulphocarbolate  Compound,  Squibb 

(Intestinal  Antiseptic) 
C.T.  Per  1000  Per  500  Per  100 


Zinc  Sulphocarbol.  1/2  gr. 

Bismuth  Subgallate  2  gr. 

Betanaphthol  1/2  gr. 

Copper  Arsenite  1/200  gr. 

Oil  Cinnamon  q.  s. 


Disordered  digestion,  coated 
tongue,  flatulence  and  intes- 
tinal catarrh  are  the  indica- 
tions for  the  use  of  this 
formula.  Copper  arsenite  acts 


as  an  alterative  and  antisep- 
tic and  is  ranked  among  the  best  remedies  in  intestinal  indigestion 
and  diarrhea,  acting  equally  well  in  acute  or  chronic  cases. 
Betanaphthol  is  considered  a  reliable  antiseptic.  Zinc  Sulpho- 
carbolate and  bismuth  subgallate  tend  to  overcome  atonic  con- 
ditions of  the  mucous  membrane  and  to  allay  the  irritable  and 
inflammatory  state  of  the  alimentary  canal.  Dose:  1  or  2  tab- 
lets with  water  every  three  or  four  hours  until  relieved;  then 
1  tablet  after  meals. 


HYPOPERMIC  TABLETS 

Bottle  Tube 

of  100  of  25 

fApomorphine  Hydrochloride  1/20  gr.,  Squibb 
fApomorphine  Hydrochloride  1/10  gr.,  Squibb 
Atropine  and  Morphine.  See  Morphine  and  Atropine. 


Since  we  make  only  one  quality  of  each  product,  that  best 
suited  to  the  purposes  intended,  the  specification  "Squibb's" 
is  not  open  to  various  interpretations,  but  has  a  plain,  positive 
meaning.  When  ordering  or  prescribing,  specify  SQUIBB'S. 


426        SQUIBB'S  MATERIA  MEDICA 

(Hypodermic    Tablets,    Conl.) 

Bottle  Tuba 

of  100  of  25 

Atropine  Sulphate  1/200  gr.,  Squibb 

Atropine  Sulphate  1/150  gr.,  Squibb 
Atropine  Sulphate  1/100  gr.,  Squibb 
Atropine  Sulphate  1/50  gr.,  Squibb 
Caffeine  Citrated  1/4  gr.,  Squibb 
Caffeine  Citrated   1/2  gr.,  Squibb 

Caffeine  and  Sodium  Benzoate, 
1/4  gr.,  Squibb 

Caffeine  and  Sodium  Benzoate 
1/2  gr.,  Squibb 

Caffeine  and  Sodium  Benzoate 
1  gr.,  Squibb 

fCocaine  Hydrochloride  1/10  gr.,  Squibb 

fCocaine  Hydrochloride  1/4  gr.,  Squibb 

fCodeine  Phosphate  1/8  gr.,  Squibb 

fCodeine  Phosphate  1/4  gr.,  Squibb 

fCodeine  Phosphate  1/2  gr.,  Squibb 

fCodeine  Phosphate  1  gr.,  Squibb 

fCodeine  Sulphate  1/16  gr.,  Squibb 

fCodeine  Sulphate  1/8  gr.,  Squibb 

fCodeine  Sulphate  1/4  gr.,  Squibb 

fCodeine  Sulphate  1/2  gr.,  Squibb 

fCodeine  Sulphate  1  gr.,  Squibb 

fDiacetylmorphine  Hydrochloride  1/24  gr.,  Squibb 

f Diacetylmorphine  Hydrochloride"  1/12  gr.,  Squibb 

fDiacetylmorphine  Hydrochloride  1/6  gr.,  Squibb 

Digitalin  1/100  gr.,  Squibb 

Digitalin  1/50  gr.,  Squibb 

Digitalin   1/25  gr.,  Squibb 

Digitalin  and  Strychnine,  Squibb 

Digitalin  !/100  gr. 

Strychnine  Sulphate  1/eo  gr- 


SQUIBB'S  MATERIA  MEDICA       427 

(Hypodermic    Tablels,    Con/.)  Bottle  Tube 

of  100  of  25 

Digitalin  and  Strychnine  Compound,  Squibb 

Digitalin  1/100  gr- 

Strychnine  Nitrate  1/eo  gr. 

Nitroglycerin  VlOO  gr- 

Eserine  Salicylate  1/100  gr.,  Squibb 
Eserine  Salicylate  1/60  gr.,  Squibb 
Eserine  Salicylate  1/50  gr.,  Squibb 
fHeroin  Hydrochloride  1/24  gr.,  Squibb 
fHeroin  Hydrochloride  1/12  gr.,  Squibb 
•j-Heroin  Hydrochloride  1/6  gr.,  Squibb 
fHubbard's  Bromides  No.  1,  Squibb 

Morphine  Hydrobromide       1/.j  gr. 

Hyoscine  Hydrobromide    1/ioo  gr- 

fHubbard's  Bromides  No.  2,  Squibb 

Morphine  Hydrobromide       !/8  gr. 
Hyoscine  Hydrobromide    VlOO  gr. 

Hyoscine     (Scopolamine)     Hydrobromide 
1/100  gr.,  Squibb 

Hyoscine  Hydrobromide  1/50  gr.,  Squibb 
Mercury  Succinimide  1/5  gr.,  Squibb 
fMorphine  Sulphate   1/16  gr.,  Squibb 
fMorphine  Sulphate  1/10  gr.,  Squibb 
fMorphine  Sulphate  1/8  gr.,  Squibb 
fMorphine  Sulphate  1/6  gr.,  Squibb 
fMorphine  Sulphate  1/4  gr.,  Squibb 
fMorphine  Sulphate  1/2  gr.,  Squibb 
fMorphine  Sulphate   1   gr.,  Squibb 
Morphine  and  Atropine  No.  1,  Squibb 

Morphine  Sulphate  1/2  gr. 

Atropine  Sulphate  Vl20  8r- 

fMorphine  and  Atropine  No.  2,  Squibb 

Morphine  Sulphate  1/4  gr. 

Atropine  Sulphate  '  VlSO  gr. 

The  founder  of  the  He;use  of  Squibb,  Dr.  Edward  R.  Squibb, 
not  only  had  high  ideals,  but  lived  and  labored  for  them;  and, 
in  the  words  of  William  Miller  Bartlett,  "the  House  of  Squibb 
stands  today  as  a  living  monument  to  the  honor,  integrity,  zeal 
and  devotion  of  its  founder." 


428        SQUIBB'S  MATERIA  MEDICA 

(Hypodermic    Tablets,    Con/.) 

Bottle  Tube 

of  100  of  25 

fMorphine  and  Atropine  No.  3,  Squibb 

Morphine  Sulphate  !/g  gr. 

Atropine  Sulphate 


fMorphine  and  Atropine  No.  4,  Squibb 

Morphine  Sulphate  !/g  gr0 

Atropine  Sulphate  1/150  gi". 

fMorphine  and  Atropine  No.  5,  Squibb 

Morphine  Sulphate  1/g  gr. 

Atropine  Sulphate  Vl50  gr« 

f  Morphine  and  Atropine  No.  6,  Squibb 

Morphine  Sulphate  */2  gr. 

Atropine  Sulphate  "VlOO 

fMorphine  and  Atropine  No.  7,  Squibb 

Morphine  Sulphate  1/4  gr. 

Atropine  Sulphate  VlOO  gr« 

fMorphine,  Atropine  and  Strychnine,  Squibb 

Morphine  Sulphate  !/8  gr. 

Atropine  Sulphate  1/150  gr- 

Strychnine  Sulphate  IJQQ  gr. 

Nitroglycerin  1/100  gr.,  Squibb 
Nitroglycerin  and  Strychnine,  Squibb 

Nitroglycerin  VlOO  8r- 

Strychnine  Nitrate  ^50  gr« 

Nitroglycerin  and  Strychnine  Compound,  Squibb 

Nitroglycerin  VlOO  gr- 

Strychnine  Nitrate  I/QQ  gr. 

Atropine  Sulphate  1/100  8r« 

Physostigmine.  See  Eserine. 
Pilocarpine   Hydrochloride    1/20   gr.,   Squibb 
Pilocarpine  Hydrochloride  1/10  gr.,  Squibb 
Potassium  Permanganate  1  gr.,  Squibb 
Scopolamine  Hydrobromide  1/200  gr.,  Squibb 
Scopolamine  Hydrobromide  1/150  gr.,  Squibb 
Scopolamine  Hydrobromide  1/iOO  gr.,  Squibb 
t  Scopolamine  and  Morphine  No.  1,  Squibb 

Scopolamine  Hydrobromide  1/ir>0  g""- 

Morphine  Hydrobromide          1/e  gr. 


SQUIBB'S  MATERIA  MEDICA       429 

(Hypodermic  Tablets,  Conl) 

Bottle  Tube 

of  100  of  25 

t  Scopolamine  and  Morphine  No.  2,  Squibb 

Scopolamine  Hydrobromide  Vi50  gr.  \ 
Morphine  Sulphate  I/Q  gr.  j 

f  Scopolamine  and  Morphine  No.  3,  Squibb 

Scopolamine  Hydrobromide  VlOO  gr. 
Morphine  Sulphate 


fScopolamine  and  Morphine  No.  4,  Squibb 

Scopolamine  Hydrobromide  1/150 
Morphine  Sulphate 


Sparteine  Sulphate  1/10  gr.,  Squibb 

Sparteine  Sulphate  1/4  gr.,  Squibb 

Sparteine  Sulphate  1/2  gr.,  Squibb 

Strychnine  Nitrate  1/100  gr.,  Squibb 

Strychnine  Nitrate  1/60  gr.,  Squibb 

Strychnine  Nitrate  1/50  gr.,  Squibb 

Strychnine  Nitrate  1/30  gr.,  Squibb 

Strychnine  Sulphate  1/400  gr.,  Squibb 

Strychnine  Sulphate  1/200  gr.,  Squibb 

Strychnine  Sulphate  1/100  gr.,  Squibb 

Strychnine  Sulphate  1/60  gr.,  Squibb 

Strychnine  Sulphate  1/50  gr.,  Squibb 

Strychnine  Sulphate  1/40  gr.,  Squibb 

Strychnine  Sulphate  1/30  gr.,  Squibb 

Strychnine  Sulphate  1/25  gr.,  Squibb 

Strychnine  Sulphate  1/20  gr.,  Squibb 

Strychnine  and   Digitalin.        See    Digitalin    and    Strychnine. 

Strychnine  and  Digitalin  Compound.        See  Digitalin  and 
Strychnine    Compound. 

Strychnine  and  Nitroglycerin.         See       Nitroglycerin       and 
Strychnine. 

The  Squibb  Ideals  have  taken  concrete  form  in  the  Squibb 
Products;  these  are  universally  recognized  as  standards  of 
uniform  Purity  and  Efficacy,  that  is,  general  Excellence  and 
Reliability.  Specify  SQUIBB'S  when  prescribing  or  ordering. 


430        SQUIBB'S  MATERIA  MEDICA 

DISPENSING  TABLETS 
For  the  convenient  preparation  of  stock  solutions. 

Bottle 
of  100 

Acid  Arsenous  1/4  gr.,  Squibb 

Acid  Arsenous  1/2  gr.,  Squibb 

Acid  Arsenous  1  gr.,  Squibb 

Atropine  Sulphate  1/2  gr.,  Squibb 

Atropine  Sulphate  1  gr.,  Squibb 

Corrosive  Sublimate  1/4  gr.,  Squibb 

Corrosive  Sublimate   1/2  gr.,  Squibb 

Corrosive  Sublimate  1  gr.,  Squibb 

Strychnine  Sulphate  1/4  gr.,  Squibb 

Strychnine  Sulphate  1/3  gr.,  Squibb 

Strychnine  Sulphate  1/2  gr.,  Squibb 

Strychnine  Sulphate  1  gr.,  Squibb 


OPHTHALMIC  TABLETS 

While  we  do  not  offer  a  complete  line  of  so-called 
"Ophthalmic  Tablets,"  we  do  make  a  number  of  tablets 
that  are  eligible  for  use  in  ophthalmic  practice,  as  collyria. 
For  convenience  of  reference  we  will  repeat  them  here. 

Acid  Boric  5  gr.,  Squibb  Per  1000      Per  500      Per  100 

Acid  Boric  and  Zinc  Sulphate,  Squibb 

Acid    Boric  5  gr. 

Zinc  Sulphate  1/4  gr. 

fCocaine  Hydrochloride  1   1/8  gr.,  Squibb 

Tube  of  25, 

Copper  Sulphate  1  gr.,  Squibb 

Per  1000       Per  500       Per  100 

Eserine  Salicylate  1/100  gr.,  Squibb 

Bottle  of  100, 
Tube  of  25, 

Eserine  Salicylate  1/60  gr.,  Squibb 

Bottle  of  100, 
Tube  of  25, 

Eserine  Salicylate  1/50  gr.,  Squibb 

Bottle  of  100, 
Tube  of  25, 
Per  1000       Per  500       Per  100 

Silver  Nitrate   1   gr.,  Squibb 
Zinc  Sulphate  1  gr.,  Squibb 


SQUIBB'S  MATERIA  MEDICA       431 


SQUIBB'S  TABLET  CASES 
Squibb's  Emergency  Pocket  Case  No.   1 

Of  black  sole  leather,  with  hand-stitched  corners  and 
spring-button  catch,  and  containing  24  filled  vials. 

Squibb's  Emergency  Pocket  Case  No.  5 

Of  black  sole  leather  and  containing  twenty  6-drachm 
screw-cap  vials  filled. 

Squibb's  Emergency  Pocket  Case  No.  8 

Of  genuine  black  grain  leather,  with  spring-button  catch, 
and  containing  24  filled  vials. 

Squibb's  Hypodermic  Tablet  Case  No.  2 

Flexible;  made  of  black  morocco  leather,  and  con- 
taining 6  tube-vials,  each  holding  25  Hypodermic  Tablets. 

Squibb's  Hypodermic  Tablet  Case  No.  3 

Of  grain  leather,  and  containing  90  tubes  of  Hypo- 
dermic Tablets  representing  a  comprehensive  assort- 
ment for  stock. 


LOZENGES 
Lozenges  Acid  Carbolic  and  Menthol,  Squibb 

(Antiseptic  Mouth  and  Throat) 

Per  1000  Per  500 


Acid  Carbolic 

Menthol 

Oil  Sassafras 

Sugar 

Acacia,  of  each 


I/. 


40  gr. 


. 
a/30  gr 


Per  100 
onditions 


Useful   in   inflamed 
of   the   mouth   and   throat,    for 
correcting   bad   breath    due    to 
decayed  teeth,   in  catarrh  and 
disordered   stomach,   and  as  a 
prophylactic        against       con- 
tagion.     Dose:     1    lozenge   dissolved   in   the   mouth   at    frequent 
intervals  until  relieved. 

Lozenges  Astringent  Throat.    See   Lozenges    Benzoic   Acid 
and  Catechu   Compound. 

fLozenges  Benzoic  Acid  and  Catechu  Compound,  Squibb 

(Astringent  Throat) 

Per  1000  Per  500  Per  100 

1/5  gr- 1      Local    Astringent    and    Seda- 
1/4  gr.   |      live,     in     sore     and     inflamed 
throat  with  cough  and  hoarse- 
ness.      Dose :      1     lozenge    on 
the    tongue    every    half    hour 


Acid    Benzoic 

Catechu 

Opium    Powdered 

Camphor 

Ext.  Yerba  Santa 

Sugar  and  Aromatics 


X/20  gr- 


q.  s.  J  or  hour  for  four  or  five 
doses,  then  at  longer  intervals 
until  relieved. 


The  Squibb  Label  on  a  package  is  a  positive  guaranty  for  the 
uniform  Purity  and  Reliability  of  the  product.  We  make  only 
ONE  quality:  the  SQUIBB  quality;  and  our  prices  are  as  low 
as  they  can  be  made  for  that  quality.  Specify  SQUIBB'S. 


432        SQUIBB'S  MATERIA  MEDICA 


Lozenges  Bronchial. 

Compound. 


See   Lozenges   Cubeb   and   Hyoscyamus 


fLozenges  Brown  Mixture  7  gr.,  Squibb 

Per  1000  Per  500 


Per  100 


Opium  Powdered 

1/20  gr. 

Acid  Benzoic 

1/20  gr. 

Camphor  Powdered 

J/20  gr- 

Tartar  Emetic 

x/40  gr. 

Oil  Anise 

Licorice 

Sugar,  of  «ach 

q.  S. 

Bronchial  irritation  and 
cough  are  allayed  by  these 
lozenges.  They  are  of  con- 
venient size  for  holding  in 
the  mouth  and  very  palat- 
able, and  the  small  dose  of 
medicament  admits  of  their 
frequent  use.  Useful  in  re- 
lieving inflammation  of  the  mucous  membrane,  hoarseness,  and 
oppression  of  the  chest,  and  in  facilitating  expectoration.  Dose : 
1  lozenge  every  half  hour  or  hour  allowed  to  dissolve  upon  the 
tongue.  Stopped  when  secretion  is  well  established  or  slight 
nausea  occurs. 

fLozenges  Brown   Mixture  with   Ammonium  Chloride* 
7  gr.,  Squibb  Per  1000  Per  500  Per  100 

The  preceding,  with  1   grain  ammonium  chloride  added. 

Lozenges  Brown  Mixture  20  gr.,  Squibb 

(75  min.  Brown  Mixture)  bottle,  lb., 

screw-cap  vials  containing  35,          per  doz. 
Opium   Powdered        3/80  gr> 
Acid  Benzoic  3/80  gr. 

Camphor  Powdered     3/so  gr. 
Tartar  Emetic  3/i60  gr. 

Oil  Anise,  Licorice, 
Sugar  of  each  q.  s. 


Dose :  1  lozenge  every  half 
hour  or  hour,  allowed  to  dis- 
solve on  the  tongue;  to  be  dis- 
continued when  expectoration 
is  well  established  or  nausea 


Lozenges    Brown    Mixture   with   Ammonium   Chloride, 
20  gr.,  Squibb  bottle,  lb 

The   preceding,   with  3   grains  ammonium   chloride   added. 

Lozenges  Cubeb  and  Hyoscyamus  Compound,  Squibb 


(Bronchial) 
Per  1000 


Per  500 


Per  100 


These  lozenges  act  as  a  stim- 
ulating Expectorant  and  mild 
Anodyne.  They  may  be  used 
freely  without  disturbing  the 
stomach,  it  is  said,  and  have 
been  found  useful  in  allaying 
bronchial  irritation  and  cougFu 
Dose :  1  lozenge  dissolved  on 
the  tongue  every  half  hour  or  hour  until  relieved. 


Oleoresm  Cubeb 

l/3  gr.  " 

Hyoscyamus 
Ammonium  Chloride 
Ext.  Licorice 

V.3  gr. 

Balsam  Tolu 
Senega 
Ipecac 

v,^: 

Vo  gr. 
1/50  gr.  . 

SQUIBB'S  MATERIA  MEDICA       433 

tLozenges  Menthol  and  Cocaine  Compound,  Squibb 

(Mentholated   Throat) 

Per  1 000  Per  500  Per  100 


Menthol  i/ss  gr. 

Cocaine    Hydrochl.    1/280  g«"- 
Oil  Anise  i/SO  min. 

Acid  Benzoic  1/12  gr. 

Eucalyptol  ^15  gr. 

Sugar  q.  s. 


Used  in  vocal  fatigue  of  pub- 
lic speakers  or  singers.  They 
are  said  to  act  as  a  stimulant 
to  the  vocal  cords,  overcome 
irritation  and  strengthen  the 


voice,   and,   in   sore   throat,    to 
relieve   the  soreness  and  pain. 

Dose :     1    lozenge  dissolved  in  the  mouth  every  fifteen  minutes 

or  half  hour  as  necessary. 

Lozenges  Orthoform  1/4  gr.,  Squibb 

Per  1000  Per  500  Per  100 

Orthoform  is  a  local  anesthetic  which  has  been  recommended  in 
lozenge  form  to  relieve  the  pain  of  swallowing  in  ulcerated  and 
tuberculous  sore  throat.  It  is  claimed  to  be  non-poisonous,  and 
to  be  without  any  effect  upon  the  mucous  membrane  save  that 
of  a  powerful  anesthetic  wherever  nerve  endings  are  exposed. 
In  dysphagia,  if  taken  about  ten  minutes  before  meals,  it  usually 
relieves  the  pain  of  swallowing  and  enables  the  patient  to  take 
food  without  discomfort.  Dose:  1  or  2  lozenges  allowed  to 
dissolve  in  the  mouth  as  occasion  requires. 

Lozenges,  Throat,  Mentholated.    See  Lozenges  Menthol  and 
Cocaine  Compound. 


TROCHES 

1  4   grainseach,  500  to  the  pound. 

Troches  Acid  Tannic,  Squibb 

Per  1000  Per  500  Per  100 

Trochisci  Acidi  Tannici.  Each  containing  1  grain  (0.065 
Gm.)  tannic  acid.  Astringent,  in  mouth  and  throat  troubles. 

Troches  Ammonium  Chloride,  Squibb 

Per  1000  Per  500  Per  100 

Trochisci  Ananonii  Chloridi.  1  1/2  grains  pure  ammonium 
chloride,  with  extract  licorice,  tragacanth,  sugar  and  syrup  tolu. 
Expectorant,  Antiseptic;  in  throat  and  bronchial  ailments. 

Troches  Catechu,  Squibb 

Per  1000  Per  500  Per  100 

Trochisci  Cambir,  N.  F.  Dropped  from  U.  S.  P.  1  grain  in 
each.  Used  in  mouth  and  throat  inflammations. 


Squibb's  Tablets  are  made  from  the  Squibb  quality  of  ingredients 
and  by  improved  processes  that  insure  accurate  dosage  and 
rapid  and  complete  disintegration  or  solution  in  the  system, 
hence  prompt  and  full  therapeutic  effect.  Specify  SQUIBB'S. 


434        SQUIBB'S  MATERIA  MEDICA 

Troches  Charcoal,  Squibb 

Per  1000  Per  500  Per  100 

Trochisci  Carbonis  Ligni,  N.  F.  About  4.6  grains  wood  char- 
coal. Absorbent,  in  fermentative  conditions  of  the  gastro- 
intestinal tract. 

Troches  Cubeb,  Squibb 

Per  1000          Per  500          Per  100 

Trochisci  Cubeba.  0.3  grain  (0.02  Gm.)  oleoresin  cubeb. 
Used  in  bronchial  troubles  and  throat  irritation. 

Troches  Cubeb  Square,  Squibb 

Per  1000  Per  500  Per  100 

One-half  strength  of  preceding. 
fTroches  Cubeb  Compound,  Squibb 

Per  1000  Per  500  Per  100 

0.3  grain  oleoresin  cubeb,  1/4o  grain  each  of  tartar  emetic  and 
morphine  sulphate;  thus  having  the  medicinal  constituents  neces- 
sary to  give  a  further  expectorant  and  alterative  together  witb 
sedative  effect  in  cases  requiring  such. 

fTroches  Cubeb  Compound  Square,  Squibb 

Per  1000  Per  500  Per  100 

One-half  strength  of  preceding. 

Troches  Elm,  Squibb  Per  1000        Per  500        Per  100 

Trochisci  Ulmi,  N.  F.  About  3  grains  slippery  elm  bark, 
flavored  with  methyl  salicylale.  Demulcent. 

Troches  Gambir.     See  Troches  Catechu. 
fTroches  Qlycyrrhiza  and  Opium,  Squibb 

Per  1000  Per  500  Per  100 

Opium  Lozenges;  Wistar's  Cough  Lozenges.  Formerly  official. 
Vl2  grain  powdered  opium,  with  extract  glycyrrhiza,  acacia, 
sugar  and  oil  anise. 

Troches  Krameria,  Squibb 

Per  1000  Per  500  Per  100 

Formerly  official.  1  grain  extract  krameria.  Astringent;  in 
mouth  and  throat  inflammations. 

Troches  Magnesia,  Squibb 

Per  1000  Per  500  Per  100 

Containing  magnesia,  nutmeg,  sugar  and  tragacanth.  Antacid, 
Carminative.  Dose:  2  or  more. 

Troches  Peppermint,  Squibb 

Per  1000       *    Per  500  Per  100 

Trochisci  Menthce  Piperiice.  */(;  minim  oil  pepoermint  in 
each.  Used  as  breath  perfume  and  carminative. 


SQUIBB'S  MATERIA  MEDICA       435 

Troches  Phenolphthalein,  Squibb 

Per  1000  Per  500  Per  100 

Trochisci  Phenolphthaleini,  N.  F.  About  1  grain  phenol- 
phthalein.  Laxative  Confection.  Average  Dose :  1  troche. 

Troches  Potassium  Chlorate,  Squibb 

Per  1000  Per  500  Per  100 

Trochisci  Potassii  Chloratis.  2!/2  grains  potassium  chlorate. 
Used  mainly  in  aphthae. 

Troches  Quinine  Tannate,  Squibb 

Per  1000  Per  500  Per  100 

Trochisci  Quinince  Tannatis,  N.  F.  About  1  grain  quinine 
tannate.  Nonbitter  form  of  quinine  medication,  especially  in- 
tended for  use  by  children  and  others  having  a  repugnance  for 
the  bitter  taste  of  quinine  sulphate.  Average  Dose :  1  troche. 

Troches  Santonin,  Squibb 

Per  1000  Per  500  Per  100 

Trochisci  Santonini,  N.  F.;  Worm  Lozenges.  1/2  grain  san- 
tonin. Dose :  I  or  2. 

Troches  Santonin  Compound,  Squibb 

Per  1000  Per  500  Per  100 

Trochisci  Santonini  Compositi,  N.  F.  About  1/3  grain  each 
santonin  and  calomel.  Vermicide.  Average  Dose :  1  troche. 
(See  also  Tablets.) 

Troches  Sodium  Bicarbonate,  Squibb 

Per  1000  Per  500  Per  100 

Trochisci  Sodii  Bicarbonatis.  4*/2  grains  sodium  bicarbonate. 
Antacid.  Dose:  as  needed. 

Troches  Sulphur  and  Cream  Tartar,  Squibb 

Per  1000  Per  500  Per  100 

Trochisci  Sulphuris  el  Potassii  Bitartralis,  N.  F.  About  4J/2 
grains  washed  sulphur  and  1  grain  cream  of  tartar.  Alterative 
and  Antipyic,  used  chiefly  in  chronic  skin  diseases.  Average 
Dose :  1  troche.  (See  also  Tablets  Sulphur  Compound.) 


PART  III 

Biological  Products 

THE  Squibb  Line  of  Antitoxins,  Serums  and  Bac- 
terial Vaccines  is  a  comprehensive  one,  yet  it  does 
not  include  any  article  of  doubtful  or  unapproved 
efficiency.  The  products  are  made  in  our  new  Research 
and  Biological  Laboratories  at  New  Brunswick,  N.  J. 
These  are  elaborately  equipped  and  thoroughly  up  to 
date  in  their  scientific  appointments  and  apparatus,  and 
are  under  the  personal  direction  of  Dr.  John  F.  Ander- 
son, formerly  Director  of  the  Hygienic  Laboratory  of  the 
U.  S.  Public  Health  Service. 

The  Squibb  Serums  are  small  in  bulk,  high  in  potency, 
and  low  in  total  solids.  They  have  been  carefully  tested 
by  laboratory  biological  tests  and  the  clinical  effect  of 
each  has  been  noted  on  the  specific  disease  for  which  it 
is  of  value.  They  have  been  especially  treated  to  elimi- 
nate serum  sickness  and  anaphylaxis. 

The  Squibb  Vaccines  are  prepared  according  to  the 
most  improved  methods.  Many  strains  of  each  organism 
are  used  in  preparing  the  stock  vaccine. 

The  Squibb  Antitoxins,  Vaccines,  and  Serums,  except 
the  Anti-Meningitic,  are  distributed  in  our  special  aseptic 
syringes,  which  may  be  depended  upon  to  give  excellent 
service.  The  Vaccines  are  furnished  also  in  aseptic  am- 
puls accompanied  by  a  syringe  to  each  package.  Squibb's 
Anti-Meningitic  Serum  is  distributed  in  our  special  Grav- 
ity Apparatus,  which  has  the  advantage  of  supplying  the 
serum  in  sterile  container  ready  for  use  by  the  gravity 
method,  by  which  latter  the  danger  of  causing  shock 
through  the  injection  is  much  minimized. 

The  directions,  as  furnished  with  each  Squibb  product, 
are  comprehensive  and  indicate  as  accurately  as  possible 
the  exact  specific  indications  for  use  of  the  same,  and 
point  out  the  conditions  under  which  it  may  be  success- 
fully employed.  Complete  literature  on  our  Biological 
Products  sent  to  physicians  on  request. 

436 


SQUIBB'S  MATERIA  MEDICA       437 

ANTITOXINS 
Diphtheria  Antitoxin,  Squibb 

In  a  special  aseptic  Syringe,  containing: 
1000  Units.     Immunizing  Dose 

(Code  Word:  Abide) 
3000  Curative  Dose 

(Code  Word:  Accident) 
5000      " 

(Code  Word:  Address) 
10000      " 

(Code  Word:  Affluence) 

Serum  Anlidiphlhericum  Purificatum.  Refined  and  concentrated; 
small  in  bulk,  high  in  potency  and  low  in  total  solids.  Curative 
Dose:  5000  units  in  ordinary  cases;  10,000  units  in  croup  and 
where  treatment  is  begun  late;  20,000  to  40,000  units  in  severe 
cases — repeated  if  required  in  12  hours.  Immunizing  Dose: 
1000  to  2000  units;  protection  lasts  2  to  4  weeks. 

Tetanus  Antitoxin,  Squibb 

In  a  special  aseptic  Syringe,  containing: 
1500  Units.     Immunizing  Dose 

(Code  Word:  Admit) 
3000       "        Curative  Dose 

(Code  Word:  Advance) 
5000      " 

(Code  Word:  Affair) 

Clear,  very  concentrated  product.  Curative  Dose:  initial, 
10,000  units,  intravenously,  with  5000  to  10,000  units  intra- 
spinally;  later  injections  at  12  to  24-hour  intervals  as  necessary. 
Immunizing  Dose:  1000  to  2000  units,  repeated  in  very  suspi- 
cious cases  once  or  twice  at  8-day  intervals.  Swab  wound 
freely  with  tincture  iodine. 


SERUMS 
Anti-Qonococcic  Serum,  Squibb 

In  a  special  aseptic  Syringe: 

2X10  Cc.  (Code  Word:  Afternoon) 

Carefully  standardized  by  opsonic  complement  fixation  tests, 
and  by  protection  tests,  and  proved  of  very  high  potency.  Indi- 
cations: Acute  gonococcic  arthritis  and  endocarditis  and  gen- 
eral sepsis  complicating  gonococcic  urethritis.  Dose :  •  20  to 
100  Cc.,  hypodermically,  every  24  hours  as  needed. 


This  house  supplies  only  one  quality  of  each  product:  that  best 
suited  to  the  purposes  intended.  The  specification  "Squibb's" 
is  not  open  to  various  interpretations;  it  has  a  plain,  posi- 
tive meaning.  Therefore,  when  prescribing,  specify  SQUIBB'S. 


438        SQUIBB'S  MATERIA  MEDICA 

Anti=Meningitic  Serum,  Squibb 

In  a  special  Gravity  Container  complete  with  needle,  rubber 
tubing,  etc.:  (Code  Word:  Agent) 

2xl5Cc. 

Indications:  Epidemic  cerebrospinal  meningitis  due  to  meningo- 
coccus  infection.  Dose:  subdurally,  after  withdrawal  of  cere- 
brospinal fluid:  1  to  5  years,  3  to  1 5  Cc.;  5  to  10  years,  5  to  15 
Cc.;  10  to  15  years,  10  to  20  Cc.;  15  to  20  years,  15  to  30 
Cc.;  20  years  and  over,  20  to  40  Cc. 

Anti=Pneumococcic  Serum,  Squibb — Type  I 

50  Cc.  Vials  (Code  Word:  Aggressive). 

Indications :  Acute  lobar  pneumonia.  Dose :  Subcutaneously, 
2  to  4  hours  before  intravenous  injection,  0.5  Cc.;  intravenously, 
50  to  100  Cc.,  preferably  mixed  with  equal  quantity  of  sterile 
physiological  salt  solution,  every  6  to  8  hours  until  crisis  is 
past.  Inject  slowly  and  preferably  by  gravity.  Warm  serum  to 
body  temperature  before  use. 

Anti=Streptococcic   Serum,   Squibb 

In  our  special  Syringe: 

2XlOCc.     '  (Code  Word:  Air) 

20  Cc.  Vials,  without  syringe,  for  local  use, 

(Code  Word:  Alloy) 

Indications:  Subcutaneously  and  intravenously,  postpartum 
sepsis,  scarlet  fever,  spreading  erysipelas,  etc.;  locally,  sup- 
purating streptococcic  wounds,  puerperal  sepsis,  etc.  Dose: 
20  to  200  Cc.,  repeated  daily  if  needed. 

Anti=Streptococcic  Serum,  Rheumatic,  Squibb 

20   Cc.   Vials,   without   syringe    (Code    Word:    Allure), 
50  Cc.  Vials,  without  syringe    (Code  Word:    Alma), 
Indications :   acute   sepsis   produced   by    streptococci   and   mani- 
fested   by    swelling    of    the    joints,    fever,    angina    and    cardiac 
complications.    Dose:    intravenously    (by   preference),   or   intra- 
muscularly or  subcutaneously,  20  Cc.  to  50  Cc.  repeated  in  24 
hours  or  oftener,   according   to  the  severity  of   the   disease   and 
the  response. 

Normal  Horse  Serum,  Squibb 

In  our  special  Syringe: 

2XlOCc.  (Code  word:  Alter) 

20  Cc.  Vials,  without  syringe,  for  local  use. 

(Code  Word:  Amalgam) 

Indications:  Subcutaneously  and  intravenously,  hemophilia, 
melaena  neonatorum,  purpura  haemorrhagica,  persistent  epistaxis, 
typhoid  hemorrhage,  gastric  and  duodenal  hemorrhage,  and 
general  hemorrhages  in  leukemia  and  other  blood  diseases;  also 
in  septic  diseases  for  which  no  immune  serums  have  been  made, 
etc.  Locally,  puerperal  sepsis  as  a  uterine  pack,  in  chronic 
suppurating  wounds  or  sinuses.  Orally,  pain  and  hemorrhage 
in  gastric  ulcer.  Dose:  Subcutaneously  20  to  30  Cc.,  repeated 
daily  and  increased  if  necessary;  Orally,  30  to  100  Cc.  every 
12  to  24  hours  as  needed. 


SQUIBB'S  MATERIA  MEDICA       439 

BACTERIAL  VACCINES 

All  the  Vaccines  listed  below  are  also  prepared  by  us, 
upon  request,  in  special  doses  that  may  be  required.  Such 
extra  doses  are  supplied  without  extra  charge. 

Acne  Vaccine,  Squibb 

In  fully  assembled  aseptic  Syringes,  containing: 

25,  50,   100,  200  million  killed  bacilli 
box  of  4  Syringes  (Code  Word:  Amaze) 

50,  200  million  killed  bacilli,  box  of  2  Syringes 

(Code  Word:  Amber) 
In  Ampuls: 

10,  25,  50,  100,  200,  500  million  killed  bacilli,  box 
of  6  Ampuls  with  Syringe 

(Code  Word:  Amiable) 

50,  200  million  killed  bacilli,  box  of  2  Ampuls  with 
Syringe  (Code  Word:  Amorous) 

Indications:  Non-pustular  acne  vulgaris  where  comedones  pre- 
dominate. Dose:  5  to  10  million  bacilli,  gradually  increasing 
to  larger  doses,  injected  every  three  to  five  days.  Squeezing  out 
comedones,  hot  applications,  massage  and  suitable  dietetic  meas- 
ures should  not  be  neglected.  (See  Staphylo-Acne  Vaccine.) 

Bacillus  Coli  Communis  Vaccine,  Squibb 

In  fully  assembled  aseptic  Syringes,  containing: 
100,  200,  500,  1000  million  killed  bacilli, 
box  of  4  Syringes 

(Code  Word:  Analysis) 
100,  500  million  killed  bacilli,  box  of  2  Syringes 

(Code  Word:  Ancestor) 

In  Ampuls: 

2X100,  2X500.  2 X.I 000  million  killed  bacilli, 
box  of  6  Ampuls  with  Syringe 

(Code  Word:  Adducing) 
100,.  500  million  killed  bacilli, 
box  of  2  Ampuls  with  Syringe 

(Code  Word:  Afflict) 

Indications :  Wounds  and  abdominal  or  pelvic  abscesses  due 
to  B.  Coli  Communis,  cystitis  and  pyelitis  from  same  cause,  etc. 
Dose:  100  million  bacilli,  rapidly  increesed  to  500  or  1000 
million  bacilli,  subcutaneously  every  three  to  five  days. 


The  prices  of  the  Squibb  Products  are  in  all  instances  as  low  as 
the  quality  and  quantity  of  ingredients  and  the  expense  of  man- 
ufacture allow.  They  include  containers,  packing  and  boxing.  When 
ordering  or  prescribing  medicinal  products,  specify  SQUIBB'S. 


440        SQUIBB'S  MATERIA  MEDICA 

Bacillus  Pertussis  Vaccine,  Squibb 

In  fully  assembled  aseptic  Syringes,  containing: 
25,  50,  100,  200  million  killed  bacilli 
box  of  4  Syringes  (Code  Word:  Anchor) 

50,  200  million  killed  bacilli,  box  of  2  Syringes 

(Code  Word:  Andante) 
In  Ampuls: 

25,  50,  100,  200,  300,  500  million  killed  bacilli, 
box  of  6  Ampuls  with  Syringe 

(Code  Word:  Andrew) 
50,  200  million  killed  bacilli, 
box  of  2  Ampuls  with  Syringe 

(Code  Word:   Anecdote) 

Indications:  Prophylactic  and  curative  of  pertussis  (whooping- 
cough).  Dose:  Prophylactic,  20,  50,  and  100  million  bacilli 
injected  at  five-day  intervals;  curative,  25,  50,  100,  200,  300 
and  500  million  bacilli,  every  day  if  needed,  according  to  the 
response  and  reaction. 

Gonococcus  Vaccine,  Squibb 

In  fully  assembled  aseptic  Syringes,  containing: 
100,  200,  350,  500  million  killed  gonococci, 
box  of  4  Syringes  (Code  Word:  Annual) 

100,  500  million  killed  gonococci,  box  of  2  Syringes 
(Code  Word:  Angel) 
In  Ampuls: 

50,   100,  150,  350,  500,   1000  million  killed  gono- 
cocci, box  of  6  Ampuls  with  Syringe 

(Code  Word:    Angllfy) 

100,  500  million  killed  gonococci,  box  of  2  Ampuls 
with  Syringe  (Code  Word:  Anthem) 

Made  from  cultures  of  many  different  strains.  Indications: 
Subacute  and  chronic  gonococcus  infection  (urethritis,  epididy- 
mitis,  prostatitis,  pyehtis,  cystitis,  arthritis,  vulvovagmitis,  salpin- 
gitis,  iritis,  endometritis,  etc.).  Dose:  100  million  gonococoi, 
increased  if  necessary  to  500  or  even  1000  million,  every 
three  to  five  days. 

Meningococcus  Vaccine  Curative,  Squibb 

In  fully  assembled  aseptic  Syringes,  containing: 

100,  200,  400,  500  million  killed  meningococci, 
box  of  4  Syringes  (Code  Word:  Appeal) 

100,  500  million  killed  meningococci, 
box  of  2  Syringes  (Code  Word:  Apply) 

In  Ampuls: 

2X100,   2X500,   2X1000  million   killed    meningo- 
cocci, box  of  6  Ampuls  with  Syringe 

(Code  Word:    Approve) 
100,  500  million  killed  meningococci, 
box  of  2  Ampuls  with  Syringe 

(Code  Word:   Apron) 


SQUIBB'S  MATERIA  MEDICA       441 

Meningococcus  Vaccine  Curative,  Squibb  (Cent.) 

Indications:  Adjunct  to  anti-meningitic  serum  in  persistent 
subacute  or  chronic  epidemic  meningitis.  Dose:  100  million 
bacteria,  increased  until  a  decided  response  is  had,  every  three 
to  five  days. 

Meningococcus  Vaccine  Immunizing,  Squibb 

Assembled  Syringes,  containing: 

100,  500,    1000  million  killed  meningococci, 

box  of  3  Syringes  (Code  Word:  Answer) 

In  Ampuls: 

100,  500,   1000  million  killed  meningococci, 

box  of  3  Ampuls  with  Syringe 

(Code  Word:  Arch) 

Indications:  Prophylactic  against  epidemic  meningitis;  affords 
a  high  degree  of  immunity.  Dose:  500,  1000  and  1000  million 
bacteria,  hypodermically,  at  intervals  of  a  week  to  ten  days. 

Pneumococcus  Vaccine,  Squibb 

In  fully  assembled  aseptic  Syringes,  containing: 

100,  200,  400,  500  million  killed  pneumococci, 
box  of  4  Syringes  (Cod«  Word:  Arrest) 

100,  500  million  killed  pneumococci, 
box  of  2  Syringes  (Code  Word:   Arrive) 

In  Ampuls: 

2X100,  2X500,  2X1000  million  killed  pneumococci, 
box  of  6  Ampuls  with  Syringe 

(Code  Word:  Arsenal) 
100,  500  million  killed  pneumococci, 
box  of  2  Ampuls  with  Syringe 

(Code  Word:  Artful) 

Indications :  Lcbar  pneumonia,  unresolving  pneumococcic 
pneumonia,  empyema,  pyorrhea  alveolaris,  chronic  rhinitis, 
sinusitis,  etc.,  caused  by  pneumococci.  Dose :  In  acute  pneu- 
monia, 20  to  100  to  500  million  bacteria,  every  three  to  five 
days;  in  chronic  cases,  larger  doses  are  given  (100  to  500  to 
1000  million). 

0  Smallpox  (Variola)  Vaccine,  Squibb 

Glycerinated.     Each  dose  in  separate  aseptic  sealed  glass 
tube.     With  bulb  and  needles. 

Box  of  5, 
(Code  Word:  Brave) 

Box  of  10, 
(Code  Word:  Brook) 


If  difficulty  is  experienced  in  procuring  any  Squibb  product, 
in  the  original  packages  here  listed,  please  notify  us ;  we 
shall  see  that  your  wants  are  met  promptly  and  satisfactorily 


442        SQUIBB'S  MATERIA  MEDICA 

Staphylo-Acne  Vaccine,  Squibb 

In  fully  assembled  aseptic  Syringes,  containing: 

100,  200,  400,  500  million  killed  staphylococci ;   and 
25,  50,  100,  200  million  killed  acne  bacilli 
box  of  4  Syringes  (Code  Word:  Attach) 

100,  500  million  killed  staphylococci;  and  50,  200 
million  killed  acne  bacilli,  box  of  2  Syringes 

(Code  Word:  Attendance) 
In  Ampuls: 

2X100,  2X500,  2X'000  million  killed  staphylo- 
cocci; and  2X20,  2X50,  2X100  million  killed  acne 
bacilli,  box  of  6  Ampuls  with  Syringe 

(Code  Word:  Attractive) 

100,  500  million  killed  staphylococci;  and  50,  200 
million  killed  acne  bacilli,  box  of  2  Ampuls  with 
Syringe  (Code  Word:  Attribute) 

Indications :  Acne,  particularly  pustular.  As  acne  infection 
is  almost  always  associated  with  the  Slaphylococcus  albus,  the 
joint  use  of  staphylococci  and  acne  bacilli  usually  gives  prompter 
results  than  acne  vaccine  alone.  Dose:  100  to  1000  million 
staphylococci  with  25  to  200  million  acne  bacilli,  every  three 
to  five  days.  (See  also  Acn«  Vaccine.) 

0  Staphylococcus  Vaccine,  Squibb 

In  fully  assembled  aseptic  Syringes,  containing: 

100,   200,    500.    1000   million    killed    staphylococci, 
box  of  4  Syringes  (Code  Word:  Author) 

100,  500  million  killed  staphylococci, 
box  of  2  Syringes  (Code  Word:  Automat) 

In  Ampuls: 

100,  250,  2X500,   1000,  2000  million  killed  staphy- 
lococci, box  of  6  Ampuls  with  Syringe 

(Code  Word:  Automobile) 
100,  500  million  killed   staphylococci, 
box  of  2  Ampuls  with  Syringe 

(Code  Word:  Autopsy) 

Containing  the  Staphylococcus  albus,  S.  aureus,  and  S.  cilreus. 
Indications:  Chronic  furunculosis,  carbuncle,  chronic  sinuses, 
sycosis,  psoas  abscess,  persistent  cutaneous  abscess,  impetigo, 
acne,  chronic  suppurating  glands,  otitis  media,  osteomyelitis — 
any  persistent  infection  due  to  staphylococci.  Dose:  100  mil- 
lion, quickly  increased  to  500,  1000  or  even  more  million  bac- 
teria, according  to  the  response,  every  three  to  five  days. 

Streptococcus  Vaccine,  Squibb 

In  fully  assembled  aseptic  Syringes,  containing: 

100,  200,  500,  1000  million  killed  streptococci, 
box  of  4  Syringes  (Code  Word:  Avoid) 

100,  500  million  streptococci,  box  of  2  Syringes 

(Code  Word:   Avowing) 


SQUIBB'S  MATERIA  MEDICA       443 

Streptococcus  Vaccine,  Squibb  (Cont.) 

In  Ampuls: 

2X100,  2X500,  2X1000  million  killed  streptococci, 
box  of  6  Ampuls  with  Syringe 

(Code  Word:  Avulsion) 
100,    500  million   killed  streptococci, 
box  of  2  Ampuls  with  Syringe 

(Code  Word:  Away) 

Indications:  Indolent  subacute  and  chronic  suppurations  of  the 
skin,  mucosae  and  joints,  due  to  streptococci — abscesses,  cellu- 
litis,  otitis  media,  chronic  mastoid  suppuration,  oral  suppuration, 
chronic  puerperal  sepsis,  chronic  streptococcic  endocarditis, 
recurrent  erysipelas,  scarlet  fever,  articular  rheumatism,  etc. 
Dose:  Curative,  100  million  streptococci,  rapidly  increased  to 
1000  million,  subcutaneously,  every  three  to  five  days;'  prophy- 
lactic of  scarlatina,  250,  500  and  1000  million  bacteria,  at 
weekly  intervals. 

©  Typhoid  Vaccine,  Squibb 

In  fully  assembled  aseptic  Syringes,  containing: 
100,  200,  500,  1000  million  killed  bacilli, 
box  of  4  Syringes 

(Code  Word:  Azure) 
100,  500  million  killed  bacilli,  box  of  2  Syringes 

(Code  Word:  Babble) 

500,  2X1000  million  killed  bacilli,  box  of  3  Syringes 
(Code  Word:   Availing) 
In  Ampuls: 

2X160,  2X500,  2X1000  million  killed  bacilli, 
box  of  6  Ampuls  with  Syringe  (Code  Word :   Bear) 
100,  500  million  killed  bacilli, 
box  of  2  Ampuls  with  Syringe 

(Code  Word:  Bedding) 
500,  2X1000  million   killed  typhoid  bacilli, 
box  of  3  Ampuls  with  Syringe 

(Code  Word:  Blacken) 

Dose:  Curative,  500  million  bacilli  as  initial,  repeated  at  four- 
day  intervals  as  long  as  required,  each  dose  increasing  by  500 
million  over  preceding  dose  unless  too  great  local  or  general 
febrile  reaction  ensue;  usually  two  to  four  injections  are  re- 
quired. Immunizing,  men  of  150  to  200  Ibs.,  500  million,  1000 
million  and  1000  million  bacilli,  at  intervals  of  seven  to  ten 
days;  women  and  children  less  in  proportion  to  their  weight. 

Note. — AH  the  above  Vaccines  are  also  supplied,  upon  re- 
quest, in  vials  containing  20  Cc.,  without  syringes,  at 
per  vial.     Write  for  Complete  Literature. 


The  Squibb  products  are  recognized  everywhere  as  the  Quality 
Standard.  They  are  of  uniform  purity  and  strength,  hence 
therapeutically  dependable.  When  ordering  or  prescribing  med- 
icinal products,  you  will  do  well  always  to  specify  SQUIBB'S. 


444       SQUIBB'S  MATERIA  MEDICA 

Autogenous  Vaccine,  Squibb 

Prepared    from    samples    of    pus    or    cultures    submitted. 
Twelve  doses  if  necessary,  in  aseptic  Ampuls 

Pasteur  Anti»Rabic  Vaccine,  Squibb 

21    treatments,   each   in   an   aseptic   sealed   Ampul,   with 
Syringe,  ready  for  use,  packed  in  Caloris  container 

(Code  Word:  Abandon) 

The  Pasteur  Treatment  for  prevention  of  rabies  is  an  established 
success.  Almost  complete  protection  may  be  expected  if  the 
full  course  of  treatments  be  instituted  promptly  after  the  bite 
of  the  rabid  animal.  The  Squibb  Treatments  are  so  prepared 
that  they  may  be  administered  by  the  physician  at  his  office 
or  at  the  house  of  the  patient. 

The  doses  of  Anti-Rabic  Vaccine  will  be  sent  daily  by  special 
delivery  mail  and  numbered  in  the  order  in  which  they  are  to 
be  administered,  commencing  with  dose  No.  1  and  continuing 
in  regular  sequence  to  the  end  of  the  treatment,  usually  21  doses. 
The  doses  should  be  kept  in  a  cool  place  until  used.  Doses 
Nos.  1  and  2  are  given  the  first  day,  doses  3  and  4  the  second 
day,  and  then  one  dose  daily  to  the  end  of  the  treatment. 


Leucocyte  Extract,  Squibb 

10  Cc.  in  our  special  aseptic  Syringe 

(Code  Word:  Boating) 

Prepared  from  healthy  leucocytes  of  the  horse,  according  to 
the  method  of  Hiss.  Indications:  acute  infectious  diseases 
where  accurate  bacteriological  diagnosis  cannot  be  made — 
erysipelas,  meningitis,  pneumonia,  septicemia,  pyemia,  acne, 
carbuncle,  furunculosis,  etc.  Also  used  in  conjunction  with 
specific  serums  and  vaccines  where  positive  diagnosis  cannot 
be  made. 

Solution    Hypophysis       (Solution  Pituitary  Body.)     See  Part 
I  of  this  book. 

Thromboplastin,  Squibb.  20  Cc.  vial, 

Made  according  to  the  method  devised  by  Dr.  Alfred  F.  Hess 
of  the  Research  Laboratory  of  the  New  York  City  Department 
of  Health.  A  true  physiological  Hemostatic,  acting  by  supplying 
normal  properties  to  the  blood  stream,  and  not  chemically.  Of 
uniform  activity;  safe,  efficient,  non-irritating  and  easily  applied. 
It  represents  the  thromboplastic  substances  contained  in  ox  brain, 
carefully  tested  physiologically  and  standardized,  and  kept  aseptic 
by  addition  of  0.3  percent,  trikresol.  Has  been  used  v.'ith  uniform 
success  in  controlling  hemorrhage  after  removal  of  adenoids  and 
other  nose  and  throat  surgery;  rectal  bleeding,  hemorrhage  after 
removal  of  hemorrhoids,  and  after  circumcision;  in  melaena  neona- 
torum,  dental  bleeding,  old  ulcers,  etc.;  by  mouth  in  gastric  or 
intestinal  hemorrhage.  Considered  indicated  in  all  types  of  hemor- 
rhage from  small  veins  and  capillaries.  Applied  direct  to  the 


SQUIBB'S  MATERIA  MEDICA       445 

Thromboplastin,  Squibb  (Cont.) 

bleeding  surface  by  means  of  cotton,  gauze  or  tampon,  kept  in  place 
a  few  minutes.  Dose :  by  mouth  in  gastric  or  intestinal  hemorrhage, 
20  mils  (Cc.),  with  a  glassful  of  water,  several  times  daily,  if 
necessary.  Keep  in  ice  box.  NOTE:  For  subcutaneous  and  intra- 
muscular infection,  to  increase  the  coagulability  of  the  blood,  Throm- 
boplastin Hypodermic  should  be  used,  in  doses  of  10  to  20  Cc. 
every  24  to  72  hours,  according  to  indicaions. 

Urease.        See  Part  I  of  this  work. 


THERAPEUTIC    INDEX 
Squibb's   Biological   Products 

Abscesses:     Bacillus    Coli    Communis    Vaccine,    Staphylococcus 
Vaccine,  Streptococcus  Vaccine. 

Acne:      Acne    Vaccine,   Staphylo-Acne   Vaccine,   Staphylococcus 
Vaccine,  Leucocyte  Extract. 

Adenitis:     Staphylococcus  Vaccine,  Streptococcus  Vaccine. 
Anthrax:     Staphylococcus  Vaccine,  Leucocyte  Extract. 

Arthritis:      Anti-Gonococcic    Serum,    Anti-Streptococcic    Serum 
Rheumaticus,   Gonococcus  Vaccine,  Streptococcus   Vaccine. 

Bleeding:     Normal  Horse  Serum,  Thromboplastin. 
Boils:     Staphylococcus  Vaccine,  Leucocyte  Extract. 
Carbuncle:      Staphylococcus   Vaccine,   Leucocyte   Extract. 
Cell  u!  it  is:      Streptococcus  Vaccine. 

Cerebro=spinal  Meningitis:     Anti-Meningitic  Serum,  Menin- 
gococcus  Vaccine. 

Conjunctivitis,  Qonorrheal:     Anti-Gonococcic  Serum,    Men- 
ingococcus  Vaccine. 

Cystitis:      Bacillus   Coli   Communis   Vaccine,   Gonococcus   Vac- 
cine. 

Dental    Bleeding:     Thromboplastin. 
Diphtheria:     Diphtheria  Antitoxin. 

Duodenal    Hemorrhage:     Normal     Horse    Serum,    Thrombo- 
plastin. 

Eczema:     Staphylococcus  Vaccine. 

Empyema:      Pneumococcus  Vaccine,  Leucocyte  Extract. 

Endocarditis:      Anti-Gonococcic    Serum,    Gonococcus    Vaccine, 
Streptococcus  Vaccine. 


Since  we  make  only  one  quality  of  each,  product,  that  best 
suited  to  the  purposes  intended,  the  specification  "Squibb's" 
is  not  open  to  various  interpretations,  but  has  a  plain,  positive 
meaning.  When  ordering  or  prescribing,  specify  SQUIBB'S. 


446       SQUIBB'S  MATERIA  MEDICA 

Endometritis  Gonorrhea):  Gonococcus  Vaccine. 
Epididymitis:       Anti-Gonococcic  Serum,   Gonococcus  Vaccine. 
Epistaxis,  Persistent:    Normal  Horse  Serum,  Thromboplastin. 

Erysipelas:  Anti-Streptococcic  Serum,  Streptococcus  Vaccine, 
Leucocyte  Extract. 

Felon:     Streptococcus  Vaccine. 

FistuIOUS  Sinuses:  Anti-Streptococcus  Serum,  Normal  Horse 
Serum,  Pneumococcus  Vaccine,  Staphylococcus  Vaccine,  Strep- 
tococcus Vaccine. 

Furunculosis:        Staphylococcus  Vaccine,  Leucocyte  Extract. 
Gastric  Hemorrhage:     Normal  Horse  Serum,  Thromboplastin. 
Gonorrhea:      Anli-Gonococcic  Serum,  Gonococcus  Vaccine. 

Gonorrheal  Rheumatism:  Anti-Gonococcic  Serum,  Gonococ- 
cus Vaccine. 

Hematemesis;  Hemophilia;  and  Hemorrhage:  Normal 
Horse  Serum,  Thromboplastin. 

Hydrophobia:     Pasteur  Anti-Rabic  Vaccine. 
Impetigo:      Staphylococcus   Vaccine. 

Infected  Wounds:  Anti-Streptococcic  Serum,  Bacillus  Coli 
Communis  Vaccine,  Staphylococcus  Vaccine,  Leucocyte  Ex- 
tract. 

Iritis,  Gonorrheal:     Gonococcus  Vaccine. 

Ischio=rectal  Abscess:  Bacillus  Coli  Communis  Vaccine. 
Staphylococcus  Vaccine,  Streptococcus  Vaccine. 

Leukemia:     Normal  Horse  Serum,  Thromboplastin. 
Lymphadenitis:   Staphylococcus  Vaccine,  Streptococcus  Vaccine. 
Mastoiditis:     Staphylococcus  Vaccine,  Streptococcus  Vaccine. 
Melasna   Neonatorum:     Normal  Horse  Serum,  Thromboplastin. 

Meningitis,  Epidemic:  Anti-Meningitic  Serum,  Meningo- 
coccus  Vaccine,  Leucocyte  Extract. 

Meningitis,  Subacute  or  Chronic:  Meningococcus  Vaccine, 
Leucocyte  Extract. 

Metrorrhagia:         Normal  Horse  Serum,  Thromboplastin. 

Middle  Ear  Disease:  Staphylococcus  Vaccine,  Streptococcus 
Vaccine. 

Orchitis:       Anti-Gonococcic  Serum,  Gonococcus  Vaccine. 

Osteomyelitis:      Staphylococcus  Vaccine. 

Otitis     Media:     Staphylococcus    Vaccine,     Streptococcus    Vac- 


SQUIBB'S  MATERIA  MEDICA       447 

Peritonitis:  Bacillus  Coli  Communis  Vaccine. 

Pertussis:  Bacillus   Pertussis   Vaccine. 

Phlegmon:  Streptococcus  Vaccine. 

Pneumonia:       Pneumococcus  Vaccine,  Leucocyte  Extract. 

Postoperative  Bleeding:     Normal    Horse    Serum,    Thrombo- 
plastin. 

Prostatitis:     Gonococcus  Vaccine. 

Psoas   Abscess:      Bacillus    Coli    Communis    Vaccine,    Staphy- 
lococcus  Vaccine,  Streptococcus  Vaccine. 

Puerperal    Sepsis:      Anti-Streptococcic   Serum,    Normal    Horse 
Serum,  Streptococcus  Vaccine. 

Purpura    Haemorrhagica:     Normal    Horse   Serum,    Thrombo- 
plastin. 

Pustular  Acne:      Staphylo-Acne  Vaccine. 

Pustular  Rosacea:    Staphylo-Acne  Vaccine. 

Pyelitis:      Bacillus  Coli  Communis  Vaccine,  Gonococcus  Vaccine. 

Pyelo=nephritis:     Bacillus  Coli  Communis  Vaccine,  Gonococcus 
Vaccine. 

Pyemia:         Leucocyte  Extract. 

Pyorrhoea   Alveolaris:   Pneumococcus  Vaccine. 

Rabies:     Pasteur  Anti-Rabic  Vaccine. 

Rectal   Abscess:      Bacillus  Coli  Communis  Vaccine,  Staphylococ- 
cus  Vaccine,  Streptococcus  Vaccine. 

Rheumatism:      Streptococcus  Vaccine,   Anti-Streptococcic  Ser- 
um Rheumatic. 

Rhinitis,    Chronic:  Pneumococcic  Vaccine. 

Salpingitis:      Bacillus     Coli     Communis     Vaccine,     Gonococcus 
Vaccine. 

Sapremia:       Leucocyte  Extract. 

Scarlet  Fever:    Anti-Streptococcic  Serum,  Streptococcus  Vaccine. 

Sepsis,  Gonococcic:      Anti-Gonococcic       Serum,       Gonococcus 
Vaccine. 

Sepsis,  Post=partum:        Anti-Streptococcic  Serum,   Leucocyte 
Extract. 

Septicemia:     Anti-Streptococcic   Serum,    Normal    Horse   S«rum, 
Leucocyte  Extract. 

The  founder  of  the  House  of  Squibb,  Dr.  Edward  R.  Squibb, 
not  only  had  high  ideals,  but  lived  and  labored  for  them;  and, 
in  the  words  of  William  Miller  Bartlett,  "the  House  of  Squibb 
stands  today  as  a  living  monument  to  the  honor,  integrity,  zeal 
and  devotion  of  its  founder." 


448       SQUIBB'S  MATERIA  MEDICA 

Sinuses,  Suppurating:  Anti-Streptococck  Serum,  Normal 
Horse  Serum,  Pneumococcic  Vaccine,  Staphylococcus  Vaccine, 
Streptococcus  Vaccine. 

Smallpox  (Variola):     Smallpox  Vaccine. 
Sore  Throat,  Septic:    Streptococcus  Vaccine. 

Suppurating  Wounds  or  Sinuses:  Anti-Streptococcic 
Serum,  Normal  Horse  Serum,  Streptococcus  Vaccine. 

Sycosis:     Staphylococcus  Vaccine. 

Tetanus:    Tetanus  Antitoxin. 

Tonsillitis:    Staphylococcus  Vaccine. 

Typhoid   Fever:     Typhoid  Vaccine. 

Ulcers,  Old.       Thromboplastin. 

Urethritis:     Anti-Gonococcic  Serum,  Gonococcus  Vaccine. 

Vaginitis,  Qonorrheal:  Gonococcus  Vaccine. 

Variola:     Smallpox  Vaccine. 

Vesiculitis:  Gonococcus  Vaccine. 

Vulvo=vaginitis,  Qonorrheal:     Gonococcus  Vaccine. 

Whooping  Cough:    Bacillus  Pertussis  Vaccine. 

Wounds,  Infected:  Anti-Streptococcic  Serum,  Bacillus  Coli 
Communis  Vaccine,  StapKylococcus  Vaccine,  Leucocyte  Ex- 
tract. 


PART  IV 

Squibb's  Analyzed  Reagents, 

Reagent  Chemicals,  Test  Solutions, 

Volumetric  Solutions, 

and  Indicators 

FOR  many  years  the  Squibb  standard  of  quality  has 
stood  for  the  best  that  can  be  produced  in  the  line 
of  drugs  and  chemicals.  To  these  lines  we  have 
added  a  list  of  Reagents,  prepared  from  our  regular  stock 
of  high-grade  chemicals  by  repeated  purification.  Each 
lot  of  chemical  is  first  sampled  in  order  to  determine  its 
suitability  for  reagent  purposes.  If  accepted,  all  possible 
impurities  present  are  carefully  determined  by  check 
analyses.  Since  the  impurities  of  reagent  chemicals  are 
present  in  very  small  amounts,  we  employ  quantities  suffi- 
ciently large  to  insure  accurate  quantitative  results.  The 
usual  procedure  consists  in  applying  tests  on  a  quantity 
of  from  10  to  20  Gm.  of  the  reagent  chemical,  and  if 
no  appreciable  reaction  is  obtained  "none"  present  is 
reported.  If,  however,  there  is  the  slightest  indication  of 
a  reaction,  then  a  suitably  large  quantity  of  the  material 
is  taken  in  order  to  obtain  a  satisfactory  weighable  result. 
With  such  reagents  as  are  employed  in  relatively  small 
quantities,  we  usually  take  10  Gm.  of  the  sample;  while 
with  others,  such  as  sodium  carbonate  or  ammonium  ox- 
alate,  which  are  used  in  larger  amounts  in  analyses,  we 
take  from  25  to  1  00  Gm.  for  each  determination.  The 
average  percentage  of  impurity  found  is  expressed  on  the 
label  in  the  nearest  higher  round  number.  For  foreign 
metals,  such  as  react  with  hydrogen  sulphide  or  ammon- 
ium sulphide,  samples  ranging  from  5  to  1 0  Gm.  are 
tested,  and  if  an  appreciable  reaction  is  noted  a  suffi- 
ciently large  quantity  is  taken  and  the  impurities  de- 
termined and  stated  on  the  label. 

449 


450        SQUIBB'S  MATERIA  MEDICA 

At  the  foot  of  this  page  we  show  an  illustration 
of  our  Reagent  labels;  and  after  that  we  present  a  list 
of  the  Reagents  now  available,  together  with  the  Test 
Solutions,  Volumetric  Solutions,  Indicators,  and  Test 
Papers  offered  under  the  Squibb  label.  We  shall  be 
glad  to  prepare  any  additional  ones  for  which  there  may 
be  a  demand. 

Prices  are  omitted.  Owing  to  the  disturbed  condition 
of  the  chemical  market,  prices  are  changing  constantly. 
We  shall  be  glad  to  receive  your  want  lists,  showing  the 
quantities  and  subdivisions  desired,  and  to  submit  our 
quotations. 

NOTE. — In  addition  to  the  list  of  Reagent  Chemi- 
cals, we  offer  a  full  line  of  chemicals  of  a  degree  of 
purity  usually  exceeding  the  standards  of  the  U.  S. 
Pharmacopoeia  and  adapted  for  all  lines  of  chemical 
work  where  the  highest  purity  Reagent  is  not  required. 
Write  for  quotations. 


SQUIBB'S  REAGENT 

Ammonium   Carbonate 

Approx.  NH4HC03NH4NH2C02 

CONTAINS:  PERCENT.: 

Non-volatile  Matter (20  Gm.)  none 

Chloride (20  Gm.)  none 

Sulphate (20  Gm.)  none 

Thiocyanate (20  Gm.)  none 

Calcium (20  Gm.)  none 

Iron (1  Gm.,  colorimetric)  none 

Tar  Bases (S  Gm.)  none 

The  figures  in  parentheses  express  the 
quantities  taken  for  each  determination.       LOT  14741 

E-RiSoyiBB  &.SONS.  NEWYORK 

MANUEACTURING  CHEMISTS  TO  THE  MEDICAL  PROFESSION  SINCE  1858 


SQUIBB'S  MATERIA  MEDICA       451 

SQUIBB'S  ANALYZED  REAGENTS 

Acid  Acetic  Glacial,  Squibb's  Reagent 

g.  s.  bottle:   5  Ibs 1    Ib 1/4  Ib 1    oz 

Tested  for:  Non-volatile  substances-HCl-SOs^SO^HCOOH- 
Ca— Fe— Empyreumatics— Heavy  Metals. 

Acid  Acetic  Anhydride,  Squibb's  Reagent 

g.  s.  bottle:   5  Ibs 1    Ib 1/4  Ib 1  .oz 

Tested  for:    Non- volatile  substances— HC1— Heavy  Metals. 

Acid   Arsenous.     See  Arsenic  Trioxide. 

Acid  Boric  (Crystals),  Squibb's  Reagent 

g.  s.  bottle:   5  Ibs 1    Ib 1/4  Ib 1    oz 

Tested  for:    CI-SO3-Ca-Alkalies-3iO2-Fe-Pb. 

Acid  Chromic.     See  Chromium  Trioxide. 

Acid  Citric,  Squibb's  Reagent 

bottle:    1    Ib 1/4    Ib I    oz 

Tested  for:    Non-volatile  substances-SO3-Ca-Fe—  Pb. 

Acid  Gallic,  Squibb's  Reagent 

bottle:    1/4  Ib 1    oz 

Tested      for:       Non-volatile      substances-Cl-SO3-Fe-Ca-Mg- 
Tannin. 

Acid  Hydrobromic  (34%),  Squibb's  Reagent 

g.  s.  bottle :    1    Ib 1/4  Ib 1    oz 

Tested       for:        Non-volatile       substances — HCl-SO3-Ca— Fe— 
Heavy  Metals-HPH2O2. 

Acid  Hydrochloric  Cone.  (36%),  Squibb's  Reagent 

g.  s. 'bottle:   5   Ibs 1    Ib 1/4  Ib 1    oz 

Tested    for:     Non-volatile    substances-Chlorine-SOs-SO^As- 
Fe-Heavy  Metals. 

Acid  Hydrochloric  (25%),  Squibb's  Reagent 

Same  as  above. 

Acid  Hydrofluoric  (42%),  Squibb's  Reagent 

ceresin  bottle :    1    Ib 1/4  Ib 1    oz 

Tested   for:     Non-volatile  substances-HCl-SO3-SOo-H2SiF6- 
Ca-Mg-Al-Fe. 

Acid  Molybdic  (85%),  Squibb's  Reagent 

bottle:    1/4   Ib 1    oz 

Tested   for:      MoO3-Cl-SO3-P2O5-NO3-As-Fe-NH3-InsoI. 
in  NH3. 

Acid  Nitric  Cone.  (69%),  Squibb's  Reagent 

g.  s.  bottle:   5   Ibs 1    Ib l/4  Ib 1    oz 

Tested  for:    Non-volatile  substances-HCl-SO3-As-HIO3-Fe- 
Heavy  Metals. 

The  Squibb  Ideals  have  taken  concrete  form  in  the  Squibb 
Products;  these  are  universally  recognized  as  standards  of 
uniform  Purity  and  Efficacy,  that  is,  general  Excellence  and 
Reliability.  Specify  SQUIBB'S  when  prescribing  or  ordering. 


452        SQUIBB'S  MATERIA  MEDICA 

Acid  Nitric  (25%),  Squibb's  Reagent 

Same  as  above. 
Acid  Oxalic,  Squibb's  Reagent 

bottle:    5  Ibs 1   Ib 1/4  lb !   oz 

Tested   for:     Non-volatile  substances-Cl-SO3-NO3-NH3-Ca- 
Fe-Pb. 

Acid  Phosphoric  (88%),  Squibb's  Reagent 

g.  s.  bottle:      5  Ibs 1  lb 1/4  lb 1  oz 

Tested    for:    Halogen    Acids-SO3-NO3-As-Ca-Mg-Fe- 
"Ous"  Acids-Heavy  Metals. 

Acid  Phospho-Tungstic,  Squibb's  Reagent 

1-oz.  bottle: 

Tested  for:    P-NH3-WO3. 

Acid  Sulphuric  (98%),  Squibb's  Reagent 

g.  s.  bottle:    5  Ibs 1    lb 1/4  lb 

Tested  for:     Non-volatile  substances-HCl-NO3-NH3-As-Fe- 
Pb-Heavy  Metals. 

Acid  Sulphurous,  Squibb's  Reagent 

g.  s.  bottle:    1    lb J4  lb 1    oz 

Tested    for:     Non -volatile    substances-As-Fe-Heavy    Metals- 
Assay. 

Acid  Tannic,  Squibb's  Reagent 

bottle:     1    lb 1/4  lb 1    oz 

Tested  for:    Non-volatile  substances-Metals-Moisture. 
Acid  Tartaric  (Pb  Free),  Squibb's  Reagent 

bottle:     1    lb l/4   lb 1    oz 

Tested  for:    Non-volatile  substances—  C1-SO3— Ca— Fe— Pb. 

Alcohol,   Anhydrous    (99.97%    by  vol.),    Squibb's    Re- 
agent 

bottle:     1   lb 1/4  lb 

Tested    for:    Gravity-Residue-Fusel    Oil-Aldehyde-Furfural- 
Oxidizable  impurities. 

Alcohol,  Methyl  (99.5%  by  wt.),  Squibb's  Reagent 

bottle:     1    lb 1/4  lb 

Tested    for:     Residue- Acetone-Empyreumatics— Oxidizable    im- 
purities. 
Aluminum  Ammonium   Sulphate,  Squibb's  Reagent 

bottle:     5  Ibs 1    lb 1/4  lb 1    oz 

Tested  for:    Cl-Ca-Mg-As-Fe-Heavy  Metals. 

Aluminum  Nitrate,  Squibb's  Reagent 

bottle:     1    lb -.1/4   lb 1    oz 

Tested  for:    C1^3O3-Ca-Mg-Fe-Heavy  Metals. 
Aluminum-Potassium  Sulphate,  Squibb's  Reagent 

bottle:    5  Ibs 1    lb l/4  lb 1    oz 

Tested  for:    CtCa-Mg-As-Fe-Heavy  Metals. 
Ammonia  Water  Cone.  (28%),  Squibb's  Reagent 

g.  s.  bottle:    5  Ibs 1   lb 1/4  lb 

Tested    for    Non-volatile    substances-Cl-SO3-Tar     Bases-Fe- 
Heavy   Metals. 


SQUIBB'S  MATERIA  MEDICA       453 

Ammonium  Carbonate  (Cubes),  Squibb's  Reagent 

bottle:     I    Ib l/4  lb 1    oz 

Tested  for:    Non-volatile  substances-Cl-SOs-CNS-Ca-Fe-Tar 

Bases-Heavy  Metals. 
Ammonium  Chloride,  Squibb's  Reagent 

bottle:     5   Ibs Mb 1/4  lb loz 

Tested     for:      Non-volatile    substances-SOs— CNS— Ca-Fe— Tar 
Bases— Heavy  Metals. 
Ammonium  Chromate,  Squibb's  Reagent 

bottle:    !/4  lb 1    oz 

Tested  for:    C^SO3-Ca-Mg-Al-Fe-Alkalies. 
Ammonium  Molybdate,  Squibb's  Reagent 

bottle:     1    lb 1/4   lb 1    oz 

Tested  for:    MoOa-Cl-SOs-NOs^CVForeign  Metals. 

Ammonium  Nitrate,  Squibb's  Reagent 

bottle:     1    lb 1/4  lb 1    oz 

Tested      for:        Non-volatile      substances— Cl-SOs— Ca-Fe— As- 
Heavy  Metals. 
Ammonium  O \alate,  Squibb's  Reagent 

bottle:     1    lb 1/4  lb 1    oz 

Tested     for:      Non-volatile    substances-Cl-SOs-Ca-Fe-Heavy 

Metals. 
Ammonium  Persulphate,  Squibb's  Reagent 

bottle:     1    lb 1/4- lb 1    oz 

Tested    for:      Non-volatile    substances-Cl-Ca-Mg-AloC>3-Fe- 

SiC»2-Heavy  Metals-Free  Acid-Assay. 
Ammonium  Phosphate  (Dibasic),  Squibb's  Reagent 

bottle:     1    lb 1/4  lb 1    oz 

Tested  for:   Cl-SCVj-NOs-COo-Ca-As-Fe-Salts  of  Alkalies. 
Ammonium  Sulphate,  Squibb's  Reagent 

bottle:     5  Ibs 1    lb l/4  lb 1    oz 

Tested    for:      Non-volatile    substances-Cl-CNS-Ca-Fe-Heavy 

Metals. 
Ammonium  Sulphocyanate,  Squibb's  Reagent 

bottle:     1    lb 1/4   lb 1    oz 

Tested    for:    Non-volatile    substances— Cl-SOs-Fe— Heavy 

Metals-Insoluble  in  Alcohol. 
Antimony=Potassium  T'artrate,  Squibb's  Reagent 

bottle:     1    lb 1/4   lb 1    oz 

Tested  for:    Cl^SO3-Ca-Fe-Pb. 
Arsenic  Trioxide,  Squibb's  Reagent 

bottle:     1    lb 1/4   lb 1    oz 

Tested   for:     Non-volatile   substances— Cl-S-Ca-Mg-Fe. 
Asbestos   Wool   Purified,   Squibb's   Reagent 

Selected,  long-fibre,  for  Gooch  Crucible  Work. 


The  Squibb  Label  on  a  package  is  a  positive  guaranty  for  the 
uniform  Purity  and  Reliability  of  the  product.  We  make  only 
ONE  quality:  the  SQUIBB  quality;  and  our  prices  are  as  low 
as  they  can  be  made  for  that  quality.  Specify  SQUIBB'S. 


454        SQUIBB'S  MATERIA  MEDICA 

Barium  Acetate,  Squibb's  Reagent 

bottle:     1    Ib 1/4  lb 1    oz 

Tested  for:    Foreign  matter  not  ppt.  by  HaSC^— Cl— NO3-SO3— 

Sr-Ca-Fe-Heavy  Metals. 
Barium  Carbonate,  Squibb's  Reagent 

bottle:     1    lb 1/4  lb 1    oz 

Tested  for:    Alkalies-Cl-SOs-Ca-Sr-Fe-Heavy  Metals, 

Barium  Chloride,  Squibb's  Reagent 

bottle:     1    lb 1/4   lb 1    oz 

Tested  for:     Foreign  matter  not  ppt.  by 
Ca-Sr-Fe-Heavy  Metals. 

Barium  Hydroxide,  Squibb's  Reagent 

bottle:     1   lb 1/4  lb 

Tested  for:    Alkalies-CI^S-CO2-Ca-^Sr-Fe-Heavy  Metals. 

Barium  Nitrate,  Squibb's  Reagent 

bottle:     1    lb l/4  lb 1    oz 

Tested  for:    Foreign  matter  not  ppt.  by  H2SO4— Cl-Sr— Ca-Fe— 

Heavy  Metals. 
Benzol  (Benzene),  Squibb's  Reagent 

bottle:     1   lb 1/4  lb 

Tested     for:      Gravity— Boiling-point-Non-volatile     substances- 

Thiophen— CS2- 
.Bismuth  Nitrate  (Crystals),  Squibb's  Reagent 

g.  s.  bottle :     I   lb 1/4  lb I    oz 

Tested  for:    Cl-SO3-As-Fe-Pb-Cu-Ag. 
Bismuth  Subnitrate,  Squibb's  Reagent 

bottle:     1    lb l/4   lb 1    oz 

Tested  for:    Cl^SO3-CC>2-Ca-Mg-Alkalies-As-Fe-Pb-Cu. 

Cadmium  Iodide,  Squibb's  Reagent 

bottle:     I    lb 1/4   lb 1    oz 

Tested  for:    SO3-Zn-Fe. 
Cadmium  Potassium  Iodide,  Squibb's  Reagent 

1-oz.  bottle: 

Tested  for:    SO3-NO3-IO3-Fe. 
Cadmium  Sulphate,  Squibb's  Reagent 

1-oz.  bottle: 

Tested  for:    Cl-Zn-Fe. 

Calcium  Carbonate  (Precipitated),  Squibb's  Reagent 

bottle:     1   lb .'.I/}  lb 

Tested    for:    SO3-Mg-Sr-Ba-Al-Fe-Heavy    Metals. 

soluble  salts. 
Calcium  Chloride   (Crystals),   Squibb's   Reagent 

bottle:     I    lb 1/4   lb I    oz 

Tested   for:    SOs-Mg-Sr-Ba-Al-Fe-Heavy   Metals. 

Calcium   Oxide    (From   Reagent  CaCO3),   Squibb's   Re= 
agent 

Mb  bottle: 

Tested      for:        Cl-SO3-NO3-CO2-P2O5-Mg-Al-SiO2-Fe- 
Alkalies. 


SQUIBB'S  MATERIA  MEDICA        455 

Carbon   Disulphide,  Squibb's   Reagent 

bottle:     1   Ib 1/4  Ib 

Tested    for:     Non-volatile    substances-SO2-SO8-Foreign    Sul- 
phides. 
Carbon  Tetrachloride,  Squibb's  Reagent 

bottle:     1    Ib 1/4   Ib 1    oz.. 

Tested   for:     Non-volatile   substances-Cl-HCl-Organic   impuri- 

ties-Aldehydes-CS2. 
Chromium  Trioxide  (Chromic  Acid),  Squibb's  Reagent 

g.  s.  bottle :    1    Ib 1/4  Ib 1    oz 

Tested  for:    SO3-HNO3-Ca-Mg-AlkaIies.       . 

Cobalt  Chloride,  Squibb's  Reagent 

g.  s.  bottle:,  1/4  Ib 1   oz. 

Tested  for:    SO3-NO3-Alkalies-Ca-Ni-Cu-Pb-Zn-Fe. 
Cobalt  Nitrate,  Squibb's  Reagent 

g.  s.  bottle:    1/4  Ib I   oz.     • 

Tested  for:     Cl-SO3-AlkaIies-Ca-Cu-Ni-Zn-Fe. 

Copper  Sulphate,  Squibb's  Reagent 

bottle:     1    Ib 1/4   Ib 1    oz 

Tested   for:     Cl-Alkalies   and   Alkaline   Earths-SiO^Fe-For- 

eign  Metals. 
Ether,  Anhydrous,  Squibb's  Reagent 

soldered  tin:    1  Ib 1/4  Ib 

Tested  for:  Sp.  Gr .-Residue-Aldehydes-Vinyl  Alcohol-Thio- 

compounds 
Ferric=Ammonium  Sulphate,  Squibb's  Reagent 

bottle:     1    Ib 1/4   Ib 1    oz 

Tested  for:    Cl-NO3-Alkalies-Cu-Fe. 
Ferric  Chloride,  Squibb's  Reagent 

bottle:     1    Ib l/4   Ib 1    oz 

Tested     for:      HCI-Basic    Salt-Fe-SO3-NO3-P2O5-As-Ca- 

Pb-Cu-Alkalies. 
Ferrous  Sulphate,  Squibb's  Reagent 

bottle:     I    Ib l/4   Ib 1    oz 

Tested  for:    Cl-Alkalies-Cu-Pb-Free  Acid. 
Iodine,  Resublimed,  Squibb's  Reagent 

g.  s.  bottle :     1    Ib J/4  Ib 1    oz 

Tested  for:    Non-volatile  substances-Cl-CN. 
Lead  Acetate,  Squibb's  Reagent 

bottle:     5   Ibs 1    Ib 1/4  Ib 1    oz 

Tested    for:      Cl-NO3-Al-Fe-Foreign    Metals-Ca-Mg- Alka- 
lies-Basic Salt. 
Lead  Nitrate,  Squibb's  Reagent 

bottle:     1    Ib 1/4   Ib 1    oz 

Tested  for:    CI-SO3-Al-Fe-Foreigg   Metals-Ca-Mg-Alkalies. 


This  house  supplies  only  one  quality  of  each  product:  that  best 
suited  to  the  purposes  intended.  The  specification  "Squibb's" 
is  not  open  to  various  interpretations;  it  has  a  plain,  posi- 
tive meaning.  Therefore,  when  prescribing,  specify  SQUIBB'S. 


Lead  Oxide  Red,  Squibb's  Reagent 

bottle:     I    Ib 1/4  Ib 1    oz 

Tested  for:    Cl-SO3-NO3-Ca-Alkalies-SiO2-Fe-Pb  metal. 

Lead  Oxide  Yellow,  Squibb's  Reagent 

bottle:     1    Ib 1/4  Ib 1    oz 

Tested    for:      Cl-CO-j-NOs^SiO^Ca-Mg-Al-Fe-Cu-Insolu- 
ble  in  Acetic  Acid. 

Lead  Peroxide  (Manganese=free),  Squibb's  Reagent 

bottle:     1    Ib 1/4  Ib 1    oz 

Tested    for:    Cl^SO3-NO3-Mn-SiO2-Water-soluble    salts- 
Assay. 

Litmus  Paper,  Squibb 

In  vials  of  100  strips  and  in  tubes  of  2  sheets. 
We  prepare  Litmus  Paper  of  three  different  degrees  of  sen- 
sitiveness. Our  regular  red  or  blue  quickly  responds  to  N/250 
alkali  or  acid  V.  S.  Our^  neutral  responds  to  either  N/1000 
alkali  or  acid  V.  S.  Our  dark-red  or  dark-blue,  for  technical 
purposes,  responds  quickly  to  N/100  alkali  or  acid  V.  S.  We 
supply  regular  "red"  or  "blue"  paper  on  unspecified  orders. 

Magnesium  Chloride,  Squibb's  Reagent 

bottle:     1    Ib 1/4   Ib 1    oz 

Tested  for:    SO3-P2O5-As-Ca-Ba-Al-Fe-Heavy  Metals. 
Magnesium  Sulphate,  Squibb-'s  Reagent 

bottle:     5   Ibs 1    Ib 1/4  Ib 1    oz 

Tested  for:     CI-P2O5-Ca-Sr-Alkalies-As-Fe-Heavy   Metals. 
Manganese  Dioxide  (Precipitated),  Squibb's  Reagent 

bottle:     1    Ib 1/4  Ib 1    oz 

Tested    for:     Cl-NO3-SO3-SiO2-Ca-Mg-Fe-Alkalies-Assay. 
Manganese  Sulphate,  Squibb's  Reagent 

bottle:     1    Ib 1/4   Ib 1    oz 

Tested  for:    CI-NO3-Ca-Mg-Fe-Alkalies. 
Mercuric  Bromide,  Squibb's  Reagent 

1-oz.  bottle: 

Tested  for:    Non-volatile  substances-Fe-As-Foreign   Metals. 
Mercuric  Chloride,  Squibb's  Reagent 

bottle:     5   Ibs 1    Ib 1/4  Ib 1    oz 

Tested   for:     Non-volatile  substances-SO3— As-Fe-Calomel  and 

Basic  Salt-Foreign  Metals. 
Mercuric  Oxide,  Red,  Squibb's  Reagent 

bottle:     1    Ib l/4   Ib 1    oz 

Tested  for:    Non-volatile  substances-CI-SO3-NO3-Fe-Pb~Cu. 
Mercury,  Squibb's  Reagent 

stone  bottle:     5  Ibs., 1    Ib 1/4  Ib I    oz 

Non-volatile  substances-Fe-Foreign  Metals. 
NickeI=Ammonium  Sulphate,  Squibb's  Reagent 

bottle:     I    Ib l/4   Ib 1    oz 

Tested  for:    Cl-NO3-Pb-Cu-Fe-Co. 

Nickel  Nitrate,  Squibb's  Reagent 

bottle:     1    Ib 1/4  Ib 1    oz 

Tested  for:  Cl-SO3-Fe-Cu-Co-Alka!ies. 


SQUIBB'S  MATERIA  MEDICA       457 

Nickel  Sulphate,  Squibb's  Reagent 

bottle:     1    Ib 1/4  Ib 1    oz 

Tested  for:    Cl-NO3-Co-Fe-Pb-Cu-Alkalies. 
Potassium  Acetate,  Squibb's  Reagent 

bottle:     1    Ib 1/4  Ib 1    oz 

Tested  for:    Cl^SO3-Ca-Fe-Heavy  Metals. 
Potassium  Bicarbonate,  Squibb's  Reagent 

bottle:    5  Ibs 1    Ib l/4  Ib 1   oz 

Tested    for:     Cl-SO3-NO3-Ca-AI^SiC>2-Fe-Heavy    Metals- 
Residue  on  ignition. 
Potassium  Bisulphate  (Crystals),  Squibb's  Reagent 

bottle:     1    Ib 1/4  Ib I    oz 

Tested    for:     Cl-NOs-As-Ca-Mg-Al^SiCVHeavy    Metals-- 
Assay. 
Potassium  Bitartrate,  Squibb's  Reagent 

bottle:     1    Ib 1/4  Ib 1    oz 

Tested  for:    Cl-SO3-Ca-NH3-AI-Fe-Pb. 
Potassium  Bromate,  Squibb's  Reagent 

1-oz.  bottle: 

Tested  for:    Cl-Bromide-SO3-Heavy  Metals. 
Potassium  Carbonate  (Anhydrous),  Squibb's  Reagent 

bottle:    5  Ibs 1    Ib 1/4  Ib 1    oz 

Tested  for:  Cl-SO3-NO3-Ca-Mg-Al-SiO2-Fe-Heavy  Metals 
Potassium  Chlorate,  Squibb's  Reagent 

bottle:    5  Ibs 1    Ib 1/4  Ib 1    oz 

Tested  for:    C1^5O3-NO3-Ca-Mg-As-Fe-Heavy  Metals. 
Potassium  Chloride,  Squibb's  Reagent 

bottle:     1    Ib l/4  Ib 1    oz 

Tested  for:    SO3-NO3-Ca-Mg-I-Fe-Heavy  Metals. 
Potassium  Chromate,  Squibb's  Reagent 

bottle:    5  Ibs 1    Ib 1/4  Ib 1    oz 

Tested  for:    Cl-SO3-Ca-Mg-Al-Fe. 
Potassium   Dichromate,   Squibb's   Reagent 

bottle:     1    Ib 1/4   Ib 1    oz 

Tested  for:    Cl-SO3-Al-Alkaline  Earths-Heavy  Metals. 
Potassium  Ferricyanide,  Squibb's  Reagent 

bottle:     5  Ibs 1    Ib l/4  Ib 1    oz 

Tested  for:    C1^SO3-CO2. 
Potassium  Ferrccyanide,  Squibb's  Reagent 

bottle:     5  Ibs 1    Ib 1/4  Ib 1    oz 

Tested  for:    C1-SO3-CO2. 
Potassium   Hydroxide  (by  Alcohol),  Squibb's  Reagent 

bottle:     1    Ib 1/4   Ib 1    oz 

Tested     for:      Cl-SOs-NOs-COo-^SiOo-Ca-Al-Fe-N-Heavy 
Metals. 


The  prices  of  the  Squibb  Products  are  in  all  instances  as  low  as 
the  quality  and  quantity  of  ingredients  and  the  expense  of  man- 
ufacture allow.  They  incrude  containers,  packing  and  boxing.  When 
ordering  or  prescribing  medicinal  products,  specify  SQUIBB'S. 


458        SQUIBB'S  MATERIA  MEDICA 

Potassium  Iodide,  Squibb's  Reagent 

bottle:     1   Ib 1/4  Ib 1   oz 

Tested     for:     Cl-CN-SOs-NOs-CO'j-KOH'-IOs-Fe-Heavy 

Metals. 
Potassium  Nitrate,  Squibb's  Reagent 

bottle:     1    Ib 1/4   Ib 1    oz 

Tested  for:    Cl-SO3-NO2-ClO3-Ca-Fe-Heavy  Metals. 
Potassium  Permanganate,  Squibb's  Reagent 

bottle:     1    Ib l/4   Ib 1    oz 

Tested  for:    Cl-SO3-NO3-ClO3-Ca-Fe. 

Potassium  Persulphate,  Squibb's  Reagent 

bottle:     1    Ib l/4   Ib 1    oz 

Tested  for:    Cl-SiCVFe-Pb-Mn-NHs. 
Potassium-Sodium    Tartrate,    Squibb's    Reagent 

bottle:     I    Ib 1/4   Ib I    oz 

Tested  for:    Halogens-SO3-NH3-Ca-Fe-Pb. 
Potassium  Sulphate,  Squibb's  Reagent 

bottle:     5   Ibs 1    lb.......l/4   Ib 1    oz 

Tested  for:    Cl-NO3-As-NH3-Ca-Mg-Fe-Heavy  Metals. 
Potassium  Sulphocyanate,  Squibb's  Reagent 

bottle:     1    Ib 1/4   Ib 1    oz 

Tested  for:    CkSO3-NH3-Fe. 
Silver1  Nitrate  (Crystals),  Squibb's  Reagent 

bottle:     1    Ib 1/4   Ib 1    oz 

Tested  for:  Cl-Cu-Bi-Pb-Fe-SiO^Ca-Alkalies. 

Sodium  Acetate  (Crystals),  Squibb's  Reagent 

bottle:     1    Ib l/4   Ib 1    oz 

Tested  for:    Cl-SO3-Ca-Fe-Heavy  Metals. 
Sodium  Acetate  Anhydrous,  Squibb's  Reagent 

bottle:     5  Ibs 1    Ib 1/4   Ib I    oz 

Tested  for:    Cl-SO3-Ca-Fe-Heavy  Metals. 

Sodium=Ammonium  Phosphate,  Squibb's  Reagent 

bottle:     5   Ibs 1    Ib 1/4   Ib..,....1    oz 

Tested  for:    Cl-^3O3-NO3-CO2-As-Ca-Fe-Heavy  Metals. 
Sodium  Bicarbonate,  Squibb's  Reagent 

bottle:     1    Ib 1/4   Ib 1    oz 

Tested      for:       CI-SOs-Mono-carbonate-NHs-Ca-NaoSoOa- 
CNS-P2O5-Al-SiO2-Fe-Heavy  Metals. 

Sodium  Bisulphate,  Squibb's  Reagent 

bottle:     1    Ib 1/4   Ib 1    oz 

Tested      for:       Cl-As-SiO^Ca-Mg-Al-Fe-Heavy      Metals- 
Assay. 
Sodium  Bisulphite,  Squibb's  Reagent 

bottle:     1    Ib 1/4   Ib 1    oz 

Tested     for:      Cl-Ca-Mg-As-Fe-Pb-Insoluble    matter-Heavy 

Metals — Assay. 
Sodium  Bitartrate,  Squibb's  Reagent 

bottle:     1    Ib 1/4   Ib 1    oz 

Tested  for:    Cl-SO3-Ca-Fe-Pb. 


SQUIBB'S  MATERIA  MEDICA       459 

Sodium  Borate,  Squibb's  Reagent 

bottle:    5  Ibs .1    Ib l/4  lb 1    oz 

Tested  for:    Cl-SO3-CC>2-Ca-Fe-Heavy  Metals. 

Sodium  Carbonate  (Crystals),  Squibb's  Reagent 

bottle:    5  Ibs 1    lb 1/4   lb 1    oz 

Tested      for:       Cl-SO3-NO3-P2O5-NH3-Ca-Mg-Al-SiO2- 
Fe-NaOH-Heavy  Metals-Loss  at   120°  C. 

Sodium  Carbonate  Anhydrous,  Squibb's  Reagent 

bottle:     I   tt> 1/4   lb 1    oz 

Tested  for:    Cl^SO3-P2O5-SiO2-Ca-NH3-Mg-Al-Fe-H2O- 
Heavy   Metals. 

Sodium  Chlorate,  Squibb's  Reagent 

bottle:     1    Ib 1/4  lb 1    oz 

Tested  for:  Cl-SO3-NO3-Ca-Mg-Fe- As-Heavy  Metals. 
Sodium  Chloride,  Squibb's  Reagent 

bottle:     1    lb 1/4  lb 1    oz 

Tested  for:  SO3-NH3-Ca-Ba-Mg-I-Fe-Heavy  Metals. 
Sodium  Citrate,  Squibb's  Reagent 

bottle:     1    lb 1/4  lb 1    oz 

Tested  for:    Cl-SO3-As-Ca-Fe-Metals. 

Sodium  Cyanide,  Squibb's  Reagent 

bottle:     1    lb 1/4   lb 1    oz 

Tested  for:  Cl-SOs-COa-Fe-CNS-Ferrocyanide-HCN. 
Sodium  Hydroxide  (by  Alcohol),  Squibb's  Reagent 

bottle:     1    lb 1/4   lb 1    oz 

Tested  for:     Cl^SOs-COs-Ca-Al^SiCVFe-N-Assay. 
Sodium  Nitrate,  Squibb's  Reagent 

bottle:     1    lb 1/4   lb 1    oz 

Tested       for:        Cl-SO3-Ca-Mg-Fe-NO2-IO3-ClO3-Heavy 
Metals. 

Sodium  Nitrite,  Squibb's  Reagent 

bottle:     1    lb 1/4   lb 1    oz 

Tested  for:    Cl-SO3-Fe-Assay. 
Sodium  Nitroprusside,  Squibb's  Reagent 

1-oz.  bottle: 
Tested  for  SO3. 

Sodium  Oxalate  (Soerensen's  Salt),  Squibb's  Reagent 

bottle:     1    lb 1/4  lb 1    oz 

Tested     for:       C1-SO3— K-Fe-Organic     Foreign     compounds- 
Hygroscopic  Moisture-Neutrality  (Bureau  of  Standards). 

Sodium  Peroxide,  Squibb's  Reagent 

bottle:     1   lb 1/4  lb 

Tested      for:       Cl-SO3-P2O5-SiO2-Al-Fe-Heavy      Metals- 
Assay. 


jf  difficulty  is  experienced  in  procuring  any  Squibb  product, 
in  the  original  packages  here  listed,  please  notify  us;  we 
shall  see  that  your  wants  are  met  promptly  and  satisfactorily. 


460       SQUIBB'S  MATERIA  MEDICA 
Sodium  Phosphate  (Dibasic),  Squibb's  Reagent 

bottle:     1    Ib l/4  Ib 1    oz 

Tested  for:    Cl-SOs-NOg-CCVAs-Fe-Heavy  Metals. 
Sodium-Potassium  Tartrate,  Squibb's   Reagent 

See  Potassium-Sodium  Tartrate. 
Sodium  Sulphate  (Crystals),  Squibb's  Reagent 

bottle:     1    Ib 1/4  Ib 1    oz 

Tested  for:    Cl-Ca-Mg-Fe-As-Heavy  Metals. 
Sodium  Sulphate  Anhydrous,  Squibb's  Reagent 

bottle:     I    Ib 1/4   Ib 1    oz 

Tested  for:    Cl-Ca-Mg-Fe-As-Heavy  Metals-H2O. 
Sodium  Thiosulphate,  Squibb's  Reagent 

bottle:     1    Ib 1/4  Ib 1   oz 

Tested    for:       SOs-SOo-S-CO^Ca-Free    Alkali-Fe-Heavy 

Metals-Assay. 
Stannous  Chloride,  Squibb's  Reagent 

bottle:       1    Ib 1/4    Ib 1     oz 

Tested  for:   SO3-NH3-As-Fe-Pb-Alkalies-Foreign   Metals. 
Sulphur  Washed,    Squibb's    Reagent 

bottle:    1    Ib l/4   Ib 1    oz 

Tested  for:    Non-volatile  substances— Alkaline  Earths-SiO2~Fe- 

Free  Acid. 
Tin   (Mossy),  Squibb's  Reagent 

bottle:     1   Ib l/4  Ib 1   oz 

Tested  for:  Fe-Pb-Cu-Zn-As. 
Uranium  Nitrate,  Squibb's  Reagent 

1-oz.  bottle: 

Tested   for:   SO3-Fe-Alkalies-Alkaline   Earths-Uranous  Salt. 

Zinc  (Mossy),  Squibb's  Reagent 

bottle:    5   Ibs 1    Ib 1/4   Ib 

Tested  for:   As-Fe-Pb-P^S. 
Zinc  Sulphate  (Granular),  Squibb's  Reagent 

bottle:  5  Ibs 1    Ib l/4  Ib 1    oz 

Tested   for:     CI-NO3-NH3-As-Fe-Foreign   Metals. 


SQUIBB'S  REAGENT  CHEMICALS 

The  following  chemicals  are  of  a  degree  of  purity  usually 
exceeding  the  standards  of  the  U.  S.  Pharmacopoeia  and 
adapted  for  all  lines  of  chemical  work  where  the  highest 
purity  Reagent  is  not  required. 

Acetone  Aluminum  Sulphate 

Acid  Lactic  Ammonia  Water  (10%) 

Acid  Oleic  Ammonium  Benzoate 

Acid  Pyrogallic  Ammonium  Citrate 

Acid  Salicylic  Ammonium  Iodide 

Acid  Stearic  Amyl  Acetate 

Acid  Trichloracetic  Amyl  Nitrite 

Aloin  Barium  Dioxide 


SQUIBB'S  MATERIA  MEDICA       461 

Reagent  Chemicals  (Continued) 


Barium  Sulphate 

Benzaldehyde 

Betanaphthol 

Bismuth  Citrate 

Bismuth  Oxide  Hydrated 

Bismuth  Subcarbonate 

Calcium  Acetate 

Calcium  Phosphate 

Chloral  Hydrate 

Chloroform 

Ether 

Ethyl  Acetate 

Ferrous  Sulphate  Dried 

Gold  and  Sodium  Chloride 

Gold  Chloride 

Hydrogen  Peroxide  Solution 

Iron  Reduced 

Kaolin 

Lead  Subacetate  Solution 

Magnesium  Sulphate  Exsiccated 

Mercuric  Chloride 

Mercuric  Iodide 

Mercuric  Oxide  Yellow 

Methylene  Blue 

Phenol 

Phenolphthalein 


Potassium  Binoxalate 
Potassium  Bromide 
Potassium  Oxalate 
Magnesium-Ammonium  Phos- 

phate 

Potassium  Phosphate  Dibasic 
Resorcin 
Sodium  Arsenate 
Sodium  Bromide 
Sodium  Carbonate  Mono- 

hydrated 

Sodium  Hypophosphite 
Sodium  Iodide 
Sodium  Phosphate  Acid 
Sodium  Salicylate 
Sodium  Tartrate 
Strontium  Acetate 
Strontium  Bromide 
Strontium  Iodide 
Sugar  of  Milk 
Zinc  Acetate 
Zinc  Carbonate 
Zinc  Chloride 
Zinc  Iodide 
Zinc  Oxide 
Zinc  Sulphate  Dried 


SQUIBB'S  TEST  SOLUTIONS 

Below  we  list  the  Test  Solutions,  Volumetric  Solutions, 
and  Indicators,  as  demanded  for  the  reactions,  tests  and 
assays  prescribed  by  the  U.  S.  Pharmacopoeia  Ninth  De- 
cennial Revision.  We  use  the  familiar  abbreviations 
"T.  S."  and  V.  S."  for  "Test  Solution"  and  "Volu- 
metric Solution,"  respectively;  N/2,  N/10,  N/50  and 
N/100,  for  "Half-Normal,"  "Tenth  Normal,"  "Fif- 
tieth-Normal" and  "Hundredth-Normal,"  respectively. 
In  glass-stopper  bottles. 

Ammonium  Carbonate  T.  S.  500  Cc.  lOOCc. 

Ammonium  Chloride  T.  S.  500  Cc.  100  Cc. 

Ammonium  Molybdate  T.  S.  500  Cc.  100  Cc. 

Ammonium  Oxalate  T.  S.  550  Cc.  lOOCe. 

Ammonium  Sulphide  T.  S.  500  Cc.  100  Cc. 

Aniline  Sulphate  T.  S.  500  Cc.  1 00  Cc. 


The  Squibb  products  are  recognized  everywhere  as  the  Quality 
Standard.  They  are  of  uniform  purity  and  strength,  hence 
therapeutically  dependable.  When  ordering  or  prescribing  me- 
dicinal products,  you  will  do  well  always  to  specify  SQUIBB'S. 


462       SQUIBB'S  MATERIA  MEDICA 


Squibb's  Test  Solutions   (Continued) 


Arsenic  Acid  T.  S.,  Concentrated  500  Cc. 

Barium  Chloride  T.  S.  500  Cc. 

Barium  Hydroxide  T.  S.  500  Cc. 

Barium  Nitrate  T.  S.  500  Cc. 

Bromine  T.  S.  500  Cc. 

Cadmium  Chloride  T.  S.  500  Cc. 

Calcium  Chloride  T.  S.  500  Cc. 

Calcium  Hydroxide  T.  S.  500  Cc. 

Calcium  Sulphate  T.  S.  500  Cc. 

Chlorine  T.  S.  500  Cc. 

Cobaltous  Chloride  T.  S.  500  Cc. 

Cobaltous  Nitrate  T.  S.  500  Cc. 

Cupric  Acetate  T.  S.  500  Cc. 

Cupric  Ammonium  Sulphate  T.  S.      500  Cc. 

Cupric  Sulphate  T.  S.  500  Cc. 

Diphenylamine  T.  S.  500  Cc. 

Esbach's  Reagent  500  Cc. 
Ferric  Ammonium  Sulphate  T.  S.        500  Cc. 

Ferric  Chloride  T.  S.  500  Cc. 

Ferrous  Sulphate  T.  S.  500  Cc. 

Gold  Chloride  T.  S.  500  Cc. 

Gold  Chloride  T.  S.,  Diluted  500  Cc. 

Haines',  for  Glucose  500  Cc. 

Hydrogen  Sulphide  T.  S.  500  Cc. 

Indigo  T.  S.  500  Cc. 

Indigo-Carmine  T.  S.  500  Cc. 

Iodine  T.  S.  500  Cc. 

Iodine  T.  S.,  Alcoholic  500  Cc. 

lodo-Bromide  T.  S.  500  Cc. 

Lead  Acetate  T.  S.  500  Cc. 

Lead  Acetate  T.  S.,  Alcoholic  500  Cc. 

Lead  Acetate  Basic  T.  S.  500  Cc. 

Manganese  Sulphate  T.  S.  500  Cc. 

Magnesia  Mixture  500  Cc. 

Magnesium  Sulphate  T.  S.  500  Cc. 
Mercuric  Bromide  T.  S.,  Alcoholic         500  Cc. 

Mercuric  Chloride  T.  S.  500  Cc. 
Mercuric  Chloride  T.  S.,  Alcoholic       500  Cc. 

Mercuric  Nitrate  T.  S.  500  Cc. 

Mercuric  Potassium  Iodide  T.  S.      500  Cc. 

Mercuric  Potassium  Iodide  T.  S., 

Alkaline  500  Cc. 

Mercurous  Nitrate  T.  S.  500  Cc. 

Naphthylamine  Acetate  T.  S.  500  Cc. 
Naphthylamine  (Alpha-)  Hydrochloride 

T.  S.  500  Cc. 

Obermayer's  Reagent  500  Cc. 

Oxalic  Acid  T.  S.  500  Cc. 
Palladous  Chloride  T.  S. 


100  Cc. 
100  Cc. 
100  Cc. 
100  Cc. 
100  Cc. 
100  Cc. 
100  Cc. 
100  Cc. 
100  Cc. 
100  Cc. 
100  Cc. 
100  Cc. 

25  Cc. 
100  Cc. 
lOOCc. 
100  Cc. 
100  Cc. 
100  Cc. 
lOOCc. 
100  Cc. 
100  Cc. 
100  Cc. 

25  Cc. 
100  Cc. 

25  Cc. 
100  Cc. 
100  Cc. 
100  Cc. 
100  Cc. 
100  Cc. 
100  Cc. 
lOOCc. 
100  Cc. 
100  Cc. 
100  Cc. 
100  Cc. 
100  Cc. 
100  Cc. 
100  Cc. 
100  Cc. 
lOOCc. 
100  Cc. 
lOOCc. 

lOOCc. 

lOOCc. 
100  Cc. 

lOOCc. 

100  Cc. 

100  Cc. 

25  Cc. 


SQUIBB'S  MATERIA  MEDICA        463 


Squibb's  Test  Solutions   (Continued) 


Phenoldisulphuric  Acid  T.  S.  500  Cc. 

Phenolphthalein  T.  S.  500  Cc. 

Phloroglucinol  T.  S.  500  Cc. 

Picric  Acid  T.  S.  500  Cc. 
Platinic  Chloride  T.  S. 

Potassium  Carbonate  T.  S.  500  Cc. 

Potassium  Chromate  T.  S.  500  Cc. 

Potassium  Cyanide  T.  S.  500  Cc. 

Potassium  Dichromate  T.  S.  500  Cc. 

Potassium  Ferricyanide  T.  S.  500  Cc. 

Potassium  Ferrocyanide  T  .S.  500  Cc. 

Potassium  Hydroxide  T.  S.  500  Cc. 
Potassium  Hydroxide  T.  S.  .Alcoholic  500  Cc. 

Potassium  Hydroxide  T.  S.,  Special  500  Cc. 

Potassium  Iodide  T.  S.  500  Cc. 

Potassium  Permanganate  T.  S.  500  Cc. 

Potassium  Sulphate  T.  S.  500  Cc. 

Potassium  Sulphocyanate  T.  S.  500  Cc. 

Pyrogallol  T.  S.,  Alkaline  500  Cc. 

Resorcinol  T.  S.  500  Cc. 

Silver-Ammonium  Nitrate  T.  S.  500  Cc. 

Silver  Nitrate  T.  S.  500  Cc. 

Silver  Sulphate  T.  S.  500  Cc. 

Sodium  Acetate  T.  S.  500  Cc. 

Sodium  Bisulphite  T.  S.  500  Cc. 

Sodium  Bitartrate  T.  S.  500  Cc. 

Sodium  Carbonate  T.  S.  500  Cc. 

Sodium  Cobaltic  Nitrite  T.  S.  500  Cc. 

Sodium  Cyanide  T.  S.  500  Cc. 

Sodium  Hypobromite  T.  S.  500  Cc. 

Sodium  Nitroprusside  T.  S.  500  Cc. 

Sodium  Phosphate  T.  S.  500  Cc. 

Sodium  Phosphotungstate  T.  S.  500  Cc. 

Sodium  Sulphide  T.  S.  500  Cc. 

Sodium  Tartrate  T.  S.  500  Cc. 

Sodium  Thiosulphate  T.  S.  500  Cc. 

Stannous  Chloride  T.  S.  500  Cc. 

Stannous  Chloride  T.  S.,  Acid  500  Cc. 

Stannous  Chloride  T.  S.,  Saturated  500  Cc. 

Sulphanilic  Acid  T.  S.  500  Cc. 

Tannic  Acid  T.  S.  500  Cc. 

Tartaric  Acid  T.  S.  500  Cc. 


lOOCc. 
100  Cc. 
100  Cc. 
lOOCc. 
25  Cc. 
100  Cc. 
100  Cc. 
100  Cc. 
100  Cc. 
lOOCc. 
lOOCc. 
100  Cc. 
lOOCc. 
100  Cc. 
lOOCc, 
lOOCc. 
lOOCc. 
lOOCc. 
100  Cc. 
lOOCc. 
lOOCc. 
100  Cc. 
100  Cc. 
100  Cc. 
100  Cc. 
lOOCc. 
lOOCc. 
lOOCc. 
lOOCc. 
100  Cc. 
100  Cc. 
100  Cc. 
100  Cc. 
100  Cc. 
100  Cc. 
lOOCc. 
100  Cc. 
100  Cc. 
100  Cc. 
100  Cc. 
100  Cc. 
100  Cc. 


SQUIBB'S  VOLUMETRIC  SOLUTIONS 

Alkaline  Cupric  Tartrate  V.  S.(Fehling's  Solution)       500  Cc. 
Barium  Hydroxide  V.  S.  N/l  0  500  Cc. 

Since  we  make  only  one  quality  of  each  product,  that  best 
suited  to  the  purposes  intended,  the  specification  "Squibb's" 
is  not  open  to  various  interpretations,  but  has  a  plain,  positive 
meaning.  When  ordering  or  prescribing,  specify  SQUIBB'S. 


464        SQUIBB'S  MATERIA  MEDICA 

Bromine  V.  S.  N/10  (Koppeschaar's  Solution)  500  Cc. 

Hydrochloric  Acid  V.  S.  Normal  500  Cc. 

Hydrochloric  Acid  V.  S.  N/2  500  Cc. 

Hydrochloric  Acid  V.  S.  N/l  0  500  Cc. 

Iodine  V.S.  N/10  500  Cc. 

Oxalic  Acid  V.S.  N/10  500  Cc. 

Oxalic  Acid  V.  S.  Normal  500  Cc. 

Potassium  Dichromate  V.  S.  N/10  500  Cc. 

Potassium  Hydroxide  V.  S.  Alcoholic  N/2                     500  Cc. 

Potassium  Hydroxide  V.  S.  Normal  500  Cc. 

Potassium  Hydroxide  V.  S.  N/l  0  500  Cc. 

Potassium  Hydroxide  V.  S.  N/5  500  Cc. 

Potassium  Hydroxide  V.  S.  N/2  500  Cc. 

Potassium  Permanganate  V.  S.  N/l  0  500  Cc. 

Potassium  Sulphocyanate  V.  S.  N/10  500  Cc. 

Silver  Nitrate  V.  S.  N/l  0  500  Cc. 

Silver  Nitrate  V.  S.  N/l  00  500  Cc. 

Sodium  Chloride  V.  S.  N/l  0  500  Cc. 

Sodium  Hydroxide  V.  S.  Double  Normal  500  Cc. 

Sodium  Hydroxide  V.  S.  Normal  500  Cc. 

Sodium  Hydroxide  V.  S.  N/l  0  500  Cc. 

Sodium  Thiosulphate  V.  S.  N/1 0  500  Cc. 

Sodium  Thiosulphate  V.  S.  N/200  500  Cc. 

Sulphuric  Acid  V.  S.  Normal  500  Cc. 

Sulphuric  Acid  V.  S.  N/2  500  Cc. 

Sulphuric  Acid  V.  S.  N/l  0  500  Cc. 

Sulphuric  Acid  V.  S.  N/50  500  Cc. 

SQUIBB'S  INDICATORS 

Azolithmin  T.  S.  500  Cc.            100  Cc. 

Brazil-Wood  T.  S.  500  Cc.            100  Cc. 

Cochineal  T.  S.  500  Cc.            100  Cc. 

Congo  Red  T.  S.  500  Cc.            100  Cc. 

Hematoxylin  T.  S.  500  Cc.            100  Cc. 

lodeosin  T.  S.  500  Cc             100  Cc. 

Litmus  T.S.  500  Cc.            lOOCc. 

Methyl-Orange  T.  S.  500  Cc.            100  Cc. 

Methyl  Red  T.  S.  500 Cc.            lOOCc. 

Phenoldisulphonic  Acid  T.  S.  500  Cc.            100  Cc. 

Rosolic  Acid  T.  S.  500  Cc.            100  Cc. 

Turmeric  Tincture  500  Cc.            100  Cc. 


PART  V 

Veterinary  Products 


VETERINARY  HYPODERMIC  TABLETS 

IN  response  to  a  demand,  we  have  added  the  follow- 
ing Veterinary  Hypodermic  Tablets  to  our  list,  and 
we  shall  increase  the  number  from  time  to  time  as, 
the  occasion  demands. 

These  tablets  contain  the  Squibb  products  of  recog- 
nized quality.  They  are  made  with  every  possible  care 
and  attention  to  detail,  and  may  be  depended  upon  for 
prompt,  certain  and  full  therapeutic  action. 

Squibb's  Veterinary  Hypodermic  Tablets  are  put  up 
in  tubes  of  10  tablets  and  in  bottles  of  100  tablets. 
Special  formulas  in  lots  of  1000  or  more  will  be  made 
to  order  at  short  notice. 

In  making  hypodermic  injections,  care  should  be 
taken  to  sterilize  the  syringe,  needle  and  site  of  opera- 
tion, so  as  to  avoid  infection ;  and  all  air-bubbles  should 
be  forced  out  of  the  syringe  before  injecting.  Only 
freshly  boiled  distilled  water  should  be  used  as  solvent. 

Tablets  Aconitine  Crystals  1/40  gr.,  Squibb 

tube  of  10,          ;  bottle  of  100, 

Tablets  Aconitine  Crystals  1/30  gr.,  Squibb 

tube  of  10,          ;  bottle  of  100, 

Tablets  Aconitine  Crystals  1/20  gr.,  Squibb 

tube  of  10,          ;  bottle  of  100, 

Aconitine   is   used   as   an   Antineuralgic,   Cardiac   Sedative   and 
Sudorific.     Antidotes:  emetics;    atropine,   digitalin  or  ammonia. 

fTablets  Apomorphine  Hydrochloride  1/10  gr.,  Squibb 

tube  of  10,          ;  bottle  of  100, 
Used  as  Emetic  in  dogs  and  cats. 


The  founder  of  the  House  of  Squibb,  Dr.  Edward  R.  Squibb, 
not  only  had  high  ideals,  but  lived  and  labored  for  them;  and, 
in  the  words  of  William  Miller  Bartlett,  "the  House  of  Squibb 
stands  today  as  a  living  monument  to  the  honor,  integrity,  zeal 
and  devotion  of  its  founder." 

465 


466        SQUIBB'S  MATERIA  MEDICA 

Tablets  Atropine  Sulphate  1/4  gr.,  Squibb 

lube  of  10,         ;  bottle  of  100, 

Tablets  Atropine  Sulphate  1/2  gr.,  Squibb 

tube  of  10,         ;  bottle  of  100, 

Tablets  Atropine  Sulphate  1  gr.,  Squibb 

tube  of  10,          ;  bottle  of  100, 

Respiratory  and  Cardiac  Stimulant;  Analgesic  and  Antispas- 
modic. 

(NOTE: — We  also  make  hypodermic  tablets  Atropine  Sulphate 
1/200  gr-  1/150  gr..  1/100  gr.,  l/50  gr.  See  Part  II.) 

Tablets  Barium  Chloride  Compound,  Squibb 

tube  of  10,          ;  bottle  of  100, 

Barium  Chloride  7  gr.  1       A    prompt   Cathartic    in    colic 

Digitalin  !/12  gr-  J       of  horses.     Dose :    1  tablet  per 

injection,    not    to   be    repeated 
before  lapse  of  24  hours. 

fTablets  Cocaine  Hydrochloride  1  gr.,  Squibb 

tube  of  10,          ;  bottle  of  100, 

fTablets  Cocaine  Hydrochloride,  1  1/2  gr.,  Squibb 

tube  of  10,          ;  bottle  of  100, 

fTablets  Cocaine  Hydrochloride  2  gr.,  Squibb 

rube  of  10,          ;  bottle  of  1 00, 

Antidotes  to  Cocaine:  chloral  hydrate;  amyl  nitrite  by  inhala- 
tion; caffeine  hypodermically. 

(NOTE: — We  also  make  hypodermic  tablets  Cocaine  Hydro- 
chloride  Vio  gr.  and  */4  gr.  See  Part  II  of  this  book.  See 
also  Tablets  Cocaine  Hydrochloride  IJ/g  gr.  and  2^/4  gr.,  for 
preparing  Solutions,  further  on.) 

Tablets  Colic.       See  Tablets.     Eserine  and  Pilocarpine. 

Tablets  Digitalin  1/4  gr.,  Squibb 

tube  of  10,          ;  bottle  of  100, 

Tablets  Digitalin  1/2  gr.,  Squibb 

tube  of  10,          ;  bottle  of  100, 

Digitalin  (Germanic)  is  used  as  a  Cardiac  Tonic  and  Diuretic; 
it  increases  the  force  and  diminishes  the  frequency  of  heart 
action.  Injections  usually  given  at  intervals  of  12  to  24  hours. 
Antidotes:  apomorphine  hypodermically  as  emetic;  nitroglycerin 
or  morphine  early,  strophanthin  later;  camphor  and  other  stimu- 
lants. 

Tablets  Eserine  Salicylate  1/4  gr.,  Squibb 

tube  of  10,          ;  bottle  of  100, 


SQUIBB'S  MATERIA  MEDICA       467 

Tablets  Eserine  Salicylate   1/2  gr.,  Squibb 

tube  of  10,          ;  bottle  of  100, 

Tablets  Eserine  Salicylate  1  gr.,  Squibb 

tube  of  10,          ;  bottle  of  100, 

Eserine  Salicylate  has  been  found  a  serviceable  Intestinal  Peri- 
staltic and  Evacuant,  and  is  largely  used  in  colic  of  horses. 
The  following  is  a  favorite  combination: 

Tablets  Eserine  and  Pilocarpine,  Squibb 

tube  of  10,          ;  bottle  of  100, 

Eserine  Salicylate  */4  gr.  \      Commonly  called  "Colic 

Pilocarpine   Hydrochlor.      1 1/2  gr- )      Tablets,"      because      of 

their  specific  use  in  colic 

of  horses.     The   pilocarpine  enhances   the  peristaltic   action  of 
the  «serine.     Dose :    1   tablet,  every  four  hours  if  needed. 
(NoTE: — We  also  make  hypodermic  tablets  Eserine  Salicylate 
VlOO  gr.,  1/60  gr.  and  Vso  gr.      See  Part  II  of  this  book.) 

•{•Tablets  Morphine  Sulphate  1  gr.,  Squibb 

tube  of  10,          ;  bottle  of  100, 

fTablets  Morphine  Sulphate  1  1/2  gr.,  Squibb 

tube  of  10,          ;  bottle  of  100, 

•{•Tablets  Morphine  Sulphate  2  gr.,  Squibb 

tube  of  10,          ;  bottle  of  100, 

Antidotes  to  Morphine:  apomorphine  hypodermically  as  emetic; 
atropine,  strychnine  or  caffeine;  exercise. 

(NoTE: — We  also  make  hypodermic  tablets  Morphine  Sulphate, 
%  gr.,  y±  gr.,  Vogr-,  %  gr.,  VlO  gr.  and  1/iegr.  See  Part  II.) 

fTablets  Morphine  and  Atropine  Comp.  No.  1,  Squibb 

Morphine  Sulphate       Wagr. )      tube    of    10, 
Atropine  Sulphate          */4  gr.  ]      bottle  of  100, 

•{•Tablets  Morphine  and  Atropine  Comp.  No.  2,  Squibb 

Morphine  Sulphate        U/2  gr.  j      tube    of     10, 
Atropine  Sulphate  */2  gr.  j       bottle  of  100, 

(NoTE: — We  also  make  hypodermic  tablets  Morphine  Sulphate 
1/2  gr.  and  Atropine  Sulphate  Vl20  gr-;  Morphine  Sulphate 
i/4  gr.  and  Atropine  Sulphate  VlfX)  gr.;  Morphine  Sulphate  Vs 
gr.  and  Atropine  Sulphate  ^OO  gr-;  Morphine  Sulphate  !/8  gr. 
and  Atropine  Sulphate  Vino  gr. ;  and  Morphine  Sulphate  1/r, 
gr.  and  Atropine  Sulphate  VloO  gr.  See  Part  II  of  this  book.) 


The  Squibb  Ideals  have  taken  concrete  form  in  the  Squibb 
Products;  these  are  universally  recognized  as  standards  of 
uniform  Purity  and  Efficacy,  that  is,  general  Excellence  and 
Reliability.  Specify  SQUIBB'S  when  prescribing  or  ordering. 


468        SQUIBB'S  MATERIA  MEDICA 

Tablets  Nitroglycerin  1/10  gr.,  Squibb 

tube  of  10,          ;  bottle  of  100, 

Antispasmodic  and  Vasodilator.  Antidotes:  atropine,  extract 
ergot  or  strychnine  hypodermically;  cold  to  head. 

Tablets  Physostigmine  Salicylate.    See     Tablets     Eserine 
Salicylate 

Tablets  Pilocarpine  Hydrochloride  1/2  gr.,  Squibb 

tube  of  10,          ;  bottle  of  100, 

Cathartic.  Antidotes:  apomorphine  as  emetic;  atropine;  am- 
monia. 

Tablets  Strychnine  Sulphate  1/4  gr.,  Squibb 

tube  of  10,          ;  bottle  of  100, 

Antidotes:  apomorphine  as  emetic;  chloral  with  bromides  per 
rectum;  chloroform  by  inhalation  if  required. 

Tablets  Strychnine  Sulphate  1/2  gr.,  Squibb 

tube  of  10,          ;  bottle  of  100, 

Tablets  Strychnine  Sulphate  1  gr.,  Squibb 

tube  of  10,          ;  bottle  of  100, 

(NoTE: — We  also  make  hypodermic  tablets  Strychnine  Sul- 
phate V400  gr.,  1/300  gl"-.  1/200  gr.,  1/100  gr.,  VfiO  gr.,  ]/.r>0  gr., 
V40  gr-.  1/30  gr.,  1/25  gr.,  and  VOQ  gr.  See  Part  II  of  this  book.) 

Tablets  Veratrine  Hydrochloride,  1/2  gr.,  Squibb 

tube  of  10,          ;  bottle  of  100, 

Cardiac  Sedative  and  Antipyretic,  in  horses  and  cattle.  Should 
be  injected  well  diluted,  and  its  effect  carefully  watched.  Anti- 
dotes: apomorphine  as  emetic;  morphine  with  atropine;  stimu- 
lants. 


SOLUTION  TABLETS 

We  append  a  list  of  a  number  of  tablets  used  by  Veteri- 
narians for  preparing  solutions : 

fTablets  Cocaine  Hydrochloride  1  1/8  gr.,  Squibb 

tube  of  25,          ;  bottle  of  100, 

1  tablet  dissolved  in  1  fluidrachm  of  water  yields  approximately 
a  2-percent,  solution ;  1  tablet  in  2  fluidrachms  of  water  a 
1 -percent,  solution;  2  tablets  in  1  fluidrachm  of  water  a  4- 
percent.  solution,  etc.  Distilled  or  sterile  water  should  always 
be  used  in  preparing  solutions;  and  if  for  hypodermic  use,  the 
solution  should  be  passed  through  absorbent  cotton. 

fTablets  Cocaine  Hydrochloride  2  1/4  gr.,  Squibb 

tube  of  25,          ;  bottle  of  100, 

1  tablet  dissolved  in  1  fluidrachm  of  water  yields  approximately 
a  4-percent,  solution. 


SQUIBB'S  MATERIA  MEDICA       469 

Tablets  Mercury  Bichloride  Compound  Bernays',  Small 

Perlb.     Per  1000     Per  500     Per  100 
Blue  or  White 

Mercury  Bichloride  !3/4gr.  }  The  addition  of  citric  acid  to 
Citric  Acid  87/100  gr-  )  mercury  bichloride  prevents 

precipitation  of  the  mercury  as 

an  albuminate,  when  used  as  an  antiseptic  on  open  wounds  or 
mucous  surfaces.  The  tablets  offered  here  are  extremely  solu- 
ble and  very  convenient  for  preparing  antiseptic  solutions.  Dis- 
solved in  water  m  the  proportion  of  1  tablet  to  4  fluidounces, 
they  yield  a  perfectly  clear,  light-blue  solution  containing  about 
one  part  of  corrosive  sublimate  in  one  thousand.  These  tablets 
are  poisonous  and  should  be  kept  in  a  safe  place.  The  fc/ue 
tablets  will  be  supplied  on  unspecified  orders.  Antidotes:  as  in 
Part  I  under  Mercury  Chloride  Corrosive. 

Tablets  Mercury  Bichloride  Compound  Bernays',  Large 

Perlb.     Per  1000     Per  500     Per  100 
Blue  or  White 

bottles   of   25,    per    doz., 

Mercury  Bichloride  7^/io  gr.  |  For  external  use  only.  One 
Citric  Acid  34/s  gr. }  tablet  dissolved  in  a  pint  of 

water    yields    a    solution    con* 

taining  one  part  of  corrosive  sublimate  in  one  thousand.  These 
tablets  are  poisonous  and  are  intended  only  for  preparing  anti- 
septic solutions.  They  should  be  kept  in  a  safe  place.  The  blue 
tablets  will  be  supplied  on  unspecified  orders. 

Tablets  Mercury  Bichloride  Compound,  Wilson's 

Perlb.     Per  1000     Per  500         Per  100 
Blue  or  White 

bottles  of  25,  per  doz., 

Mercury  Bichloride  73/io  gr.  j  These  tablets  are  intended  for 
Ammonium  Chloride  77/io  gr.  j  preparing  antiseptic  solutions. 

They  are  made  without  the  ad- 
dition of  any  foreign  matter  and  yield  perfectly  clear  solutions 
with  water.  1  tablet  dissolved  in  a  pint  of  water  makes  a  solu- 
tion of  about  1  :IOOO.  These  tablets,  being  poisonous,  should  be 
kept  in  a  place  apart  from  the  usual  internal  remedies.  The 
white  tablets  will  be  supplied  on  unspecified  orders. 
(NoTE: — With  hard  water,  that  is,  water  containing  considera- 
ble lime  salts,  Wilson's  Tablets  are  apt  to  give  rise  to  precipita- 
tion. This  cannot  be  avoided ;  and  in  such  instances  they  should 
be  replaced  by  Bernays'  Tablets,  the  citric  acid  in  which  tends 
to  prevent  precipitation.) 


The  Squibb  Label  on  a  package  is  a  positive  guaranty  for  the 
uniform  Purity  and  Reliability  of  the  product.  We  make  only 
ONE  quality:  the  SQUIBB  quality;  and  our  prices  are  as  low 
as  they  can  be  made  for  that  quality.  Specify  SQUIBB'S. 


470        SQUIBB'S  MATERIA  MEDICA 

Tablets  Potassium  Arsenite,  Squibb 

tube  of  10,          ;boHleoflOO, 

For  preparing  Foroler's  Solution  (Solution  Potassium  Arsenite). 
One  tablet  dissolved  in  V£  fluidounce  of  distilled  water  makes  a 
preparation  of  the  strength  of  Liquor  Potassii  Arsenilis  U.  S. 
P.,  but  without  compound  tincture  of  lavender. 

Tablets  Potassium  Permanganate  5  gr.,  Squibb 

Per  1000,          ;  per  500,          ;  per  100, 

For  preparing  disinfectant  solutions.  Dissolve  1  to  2  tablets  in 
a  quart  of  water.  These  tablets  are  made  from  the  Squibb  dis- 
tinctive quality  of  all  large-crystal  permanganate,  and  dissolve 
quickly  in  water.  (Also  supplied  in  1,  2  and  3-gr.  sizes.) 

fVeterinary  Hypodermic  Tablet  Case,  Squibb 

containing  12  tubes, 


Anti=Hog=Cholera  Serum,  Squibb       250  Cc.  bottle. 

Clear,  potent,  free  from  irritating  foreign  bodies  and  from  dis- 
ease-producing bacteria.  Affords  positive  protection  against  Hog 
Cholera.  Write  for  complete  literature. 


Ophthalmic  Mallein,  Squibb 

For   conjunctival   test   for   Glanders. 

5  capillary  tubes,  sufficient  for  5  tests, 

10  capillary  tubes,  sufficient  for  10  tests, 

1  Cc.  vial,  sufficient  for  50  tests, 

Torrey's  Canine  Distemper  Vaccine,  Squibb 

5  Cc.  vial  (1  treatment), 
An  effective  prophylactic  measure  against  Distemper  in  dogs. 

Torrey's  Distemper  Serum,  Squibb  20  Cc.  vial. 

For  the  efficient  treatment  of  cases  of  Canine  Distemper.     Com- 
plete literature  sent  on  request. 

Veterinary  Tetanus  Antitoxin,  Squibb 

In  special  aseptic  Syringes:  500  Units,  Immunizing  Dose, 
1  500  Units,  Immunizing  Dose, 
5000  Units,  Curative  Dose. 

Veterinary  Tuberculin,  Squibb 

For  diagnosis  of  Tuberculosis  in  cattle,  hogs  and  other  animals. 

2  Cc.  vial,  sufficient  for  1  test, 
20  Cc.  vial,  sufficient  for  10  tests, 

Veterinary  Mallein  Solution,  Squibb 

For  subcutaneous  test  for  Glanders. 

2  Cc.  vial,  sufficient  for  1  test, 
20  Cc.  vial,  sufficient  for  10  tests, 


PART  VI— MISCELLANEOUS 
Glossary  of  Therapeutic  Terms 

Used  Throughout  This  Book 

Absorbents  are  products  that  absorb  moisture,  wound 
secretions,  or  gas,  and  render  them  inert. 

Alteratives  are  agents  which  in  some  way  not  yet  un- 
derstood alter  the  processes  of  nutrition  and  excretion  and 
thereby  cure  many  diseases  of  a  chronic  type. 

Amylolytics  are  starch-digestants. 

Analeptics  are  reviving,  restorative  medicines  or  agents. 

Analgesics  or  General  Anodynes  are  internal  remedies 
relieving  pain,  either  by  direct  impression  of  the  nerve  cen- 
ters in  the  brain  or  by  diminishing  the  conductivity  of  the 
sensory  nerve  fibers. 

Anaesthetics,  Inhalation,  are  volatile  substances  produc- 
ing narcosis  or  general  insensibility  when  inhaled  in  suffi- 
cient quantity. 

Anaesthetics,  Local,  are  agents  producing  local  insen- 
sibility on  topical  application. 

Anaphrodisiacs.     See  Antaphrodisiacs. 

Anhidrotics  or  Anhydrolics.     See  Antihydrotics. 

Anodynes  or  Local  Anodynes  are  preparations  relieving 
pain  on  local  application ;  they  act  by  depression  of  the 
terminal  nerve  filaments  in  the  skin  or  by  impairing  the 
conductivity  of  the  sensory  nerves. 

Anodynes,  General.     See  Analgesics. 

Antacids  are  substances  neutralizing  acidity,  forming 
salts  with  the  acid  present. 

Antaphrodisiacs,  or  Anaphrodisiacs,  depress  the  sexual 
function  and  diminish  sexual  desire;  they  act  by  lessening 
the  excitability  of  the  nerves  of  the  genital  organs,  by  de- 
pressing the  genital  centers  in  the  brain  and  spinal  cord, 
or  by  decreasing  the  circulation  in  the  genitalia. 

Anthelmintics  are  agents  destroying  or  expelling  worms 
inhabiting  the  intestinal  canal ;  usually  tapeworm  remedies. 

Anticachectics  are  remedies  opposed  to  cachexia  (de- 
praved condition  of  general  nutrition). 

Anticatarrhals  subdue  inflammation  of  the  mucous 
membranes  (of  the  bladder,  bronchi,  nose,  etc.). 

471 


472        SQUIBB'S  MATERIA  MEDICA 

Antidiabelics  are  preparations  used  in  diabetes. 

Antiemetics  are  medicines  arresting  vomiting  (emesis). 

Antiepileptics  are  agents  employed  in  epilepsy. 

Anlierrhines  are  drugs  diminishing  nasal  discharge. 

Antifats  are  medicines  reducing  obesity. 

Antigalactics,  or  Anlilactagogues,  lessen  the  secretion 
of  milk. 

Antigonorrheics  are  preparations  used  in  gonorrhea. 
They  act  either  by  retarding  the  action  of  the  sweat 
glands,  or  by  depressing  the  excitability  of  the  perspiration 
centers,  or  by  diminishing  the  cutaneous  circulation. 

Aniihydrotics,  or  Anhydrotics,  check  excessive  pers- 
piration. 

Antilithics  are  agents  tending  to  prevent  the  formation 
of  and  to  dissolve  uric  acid  calculi. 

Antiluetics  are  agents  used  in  syphilis  (lues). 

Antimalarials.      See  Antiperiodics. 

Antineuralgics  are  preparations  relieving  or  curing  neu- 
ralgia. See  also  Analgesics. 

fAntiparasitics,  or  Parasiticides,  inhibit  the  growth  of 
or  destroy  the  animal  or  vegetable  parasites  on  the  body. 

Antiperiodics,  or  Antimalarials,  are  remedies  for  pe- 
riodic or  intermittent  fever  (malarial  fever)  ;  they  act  by 
arresting  the  development  in  the  blood  of  successive  crops 
of  the  plasmodium  malariae. 

Anlif>hlogistics  are  preparations  reducing  inflammation. 

Antif)odagrics  are  gout  remedies. 

Antipruritics  relieve  itching  (pruritus). 

Antipyics,  or  Antisuppuratives,  are  drugs  opposed  to 
the  formation  of  pus  (suppuration). 

Antipyretics  reduce  elevated  temperature  (pyrexia), 
either  by  lessening  the  production  of  heat  or  by  promoting 
the  loss  of  heat. 

Antirheumatics  are  rheumatism  remedies. 

Antiscorbutics  are  employed  in  scurvy  (scorbutus). 

Antiseptics  prevent  the  development  of  microorganisms 
causing  sepsis  or  infection. 

Antiseptics,  Intestinal,  prevent  or  check  intestinal 
sepsis  or  putrefaction. 

Antisialics,  or  Antisialagogues,  are  agents  lessening  the 
secretion  of  saliva. 

Antispasmodics  overcome  spasm  of  the  muscular 
system. 


SQUIBB'S  MATERIA  MEDICA       473 

Antitabetic,  an  agent,  used  in  tabes  dorsalis. 

Antitetanics  are  antispasmodics  employed  in  tetanus. 

Antitoxins  are  substances  developed  in  the  body  and 
counteracting  specific  toxins. 

Antituberculars  are  agents  used  in  the  treatment  of 
tuberculosis,  local  or  general  (phthisis,  consumption). 

Antizymotics,  or  Antifermentatives,  prevent  or  check 
fermentative  processes  (zymosis)  in  the  digestive  tract. 

Aperients  are  mild  cathartics,  producing  softened  stools 
\vithout  irritation. 

Aphrodisiacs  are  agents  stimulating  the  sexual  desire 
and  power. 

Appetizers  are  medicines  improving  appetite. 

Aromatics  and  Condiments  are  spicy,  stimulant  drugs. 

Astringents  contract  organic  tissue  and  thereby  lessen- 
ing or  arresting  discharge. 

Bactericides  are  products  that  kill  bacteria;  analogous 
to  disinfectants. 

Bitter  Tonics  are  vegetable  bitter  drugs  improving  ap- 
petite and  imparting  tone  to  the  digestive  organs. 

Cardiac  Depressants,  or  Cardiac  Sedatives,  lessen  the 
force  and  the  frequency  of  the  heart's  action,  and  sub- 
due cardiac  excitement. 

Cardiac  Stimulants  increase  the  force  as  well  as  the 
frequency  of  the  heart's  action  in  depressed  conditions  of 
the  circulatory  apparatus. 

Cardiac  Tonics  are  drugs  which  stimulate  the  cardiic 
musculature,  slowing  and  strengthening  its  contractions 
and  imparting  tone  to  the  weakened  organ. 

Carminatives  promote  the  expulsion  of  flatus  (gas) 
from  the  gastrointestinal  tract  by  increasing  peristalsis,  re- 
laxing the  orifices  of  the  stomach,  and  stimulating  circula- 
tion ;  they  correct  the  tendency  of  certain  drugs  to  gripe. 

Cathartics  are  agents  which  increase  or  hasten  evacua- 
tion of  the  bowels.  According  to  their  respective  intensi- 
ties or  direction  of  action,  they  are  classified  as:  Aperients 
or  Laxatives,  which  excite  only  moderate  intestinal  peris- 
talsis and  produce  softened  passages  without  irritant  ac- 
tion; Cathartics  are  Simple  Purgatives,  causing  active 
peristalsis  by  their  slightly  irritant  action  and  their  stimu- 
lating effect  upon  the  intestinal  secretions ;  Drastic  Cathar- 
tics are  still  more  drastic  in  their  action,  producing  violent 
peristalsis  and  watery  stools,  usually  with  tenesmus  and 


474        SQUIBB'S  MATERIA  MEDICA 

griping,  and  decidedly  irritating  the  intestinal  mucosa; 
Hydragogue  Cathartics  especially  produce  watery  dis- 
charges and  include  most  of  the  drastic  and  saline  purga- 
tives; Cholagogue  Cathartics  stimulate  the  flow  of  bile 
and  produce  purgation  in  consequence,  the  stools  being 
green-colored  after  full  doses;  Saline  Cathartics  stimulate 
the  intestinal  glands  and  by  dint  o-f  their  slight  diffusibility 
cause  an  accumulation  of  fluid  in  the  intestines,  and  this  in 
turn  produces  the  catharsis  partly  from  the  effect  of  gravity 
and  partly  by  mild  peristaltic  stimulation. 

Caustics,  or  Escharotics,  are  substances  used  to  de- 
stroy pathologic  organic  tissue,  either  by  abstracting  water, 
or  by  uniting  with  the  albumin,  or  by  converting  the  tissue 
into  carbon  or  gaseous  substances. 

Cerebral  Depressants  depress  or  temporarily  suspend 
the  functions  of  the  cerebrum. 

Cerebral  Excitants  or  Stimulants  increase  the  functional 
activity  of  the  brain,  partly  by  increasing  the  rapidity  of 
the  circulation  and  in  part  by  a  direct  action  upon  the 
gray  matter. 

Chalybeates  are  ferruginous  hematinics. 

Cholagogues  are  agents  promoting  the  secretion  of  bile. 

Cicatrizants  are  vulneraries  bringing  about  healing  by 
cicatrization. 

Circulatory  Equalizers  are  medicaments  restoring  the 
equilibrium  of  the  circulatory  apparatus. 

Condiments  are  spicy  preparations  stimulating  digestion. 

Corrigents  are  products  employed  to  correct  the  taste, 
or  to  overcome  untoward  action  such  as  griping,  etc. 

Counter-irritants  are  used  to  produce  superficial  irrita- 
tion in  order  to  exert  a  good  effect  upon  a  deeper-seated, 
diseased  part  or  organ. 

Demulcents  are  mucilaginous  or  oily  preparations  sooth- 
ing and  protecting  the  parts  with  which  they  come  into 
contact,  generally  the  mucous  membranes: 

Deodorants  are  substances  correcting  foul  odors. 

Depilatories  are  means  of  removing  superfluous  hair. 

Depressants  diminish  functional  activity. 

Dermics  are  agents  used  in  skin  diseases. 

Diaphoretics  and  Sudorifics  produce  increased  per- 
spiration (diaphoresis)  the  latter  being  the  more  energetic. 

Digestants  or  Digestives,  are  medicaments  that  digest 
food  or  aid  functional  digestion. 


SQUIBB'S  MATERIA  MEDICA       475 

Discutienls  are  local  agents  favoring  the  disappear- 
ance of  tumors  and  inflammatory  exudates. 

Disinfectants  are  agents  destroying  disease  germs  and 
noxious  products  of  decomposition  or  fermentation. 

Diuretics  increase  the  excretion  of  urine,  either  by  rais- 
ing the  blood-pressure  and  thereby  increasing  the  renal 
secretion,  or  by  stimulating  the  secretory  cells  or  the  nerves 
of  the  kidneys. 

Drastics,  or  Drastic  Cathartics,  are  very  energetic  pur- 
gatives, producing  violent  peristalsis  by  their  irritant  action 
on  the  intestinal  mucous  membrane. 

Ecbolics  are  agents  promoting  parturition  or  producing 
abortion,  by  stimulating  the  gravid  uterus  to  contraction. 

Emetics  are  substances  causing  vomiting  (emesis), 
either  by  irritating  the  terminations  of  the  gastric,  pharyn- 
geal,  or  esophageal  nerves,  or  by  action  through  the  blood 
upon  the  vomiting  center,  or  by  reflex  action  from  peri- 
pheral sources. 

Emmenagogues  are  used  for  restoring  or  stimulating 
the  menstrual  function,  either  by  direct  action  upon  the 
uterine  musculature  or  indirectly  improving  the  blood  and 
nerve  system. 

Emollients  soften  and  soothe  irritated  or  tense  skin. 

Epispastics  are  blistering  agents ;  vesicants. 

Errhines  are  drugs  increasing  nasal  secretion,  usually 
without  causing  sneezing. 

Escharotics.     See  Caustics* 

Excitomotors  are  agents  exciting  nerve  activity. 

Expectorants  are  remedies  which  promote  expectora- 
tion by  modifying  the  secretion  of  the  respiratory  mucous 
membranes  and  facilitating  its  expulsion. 

Febrifuges  are  fever-dispellers ;  antipyretics. 

Calactagogues  are  agents  increasing  the  secretion  of 
milk. 

Castric  Tonics  are  preparations  that  tone  up  the  stom- 
ach and  improve  digestion. 

Germicides  are  agents  that  kill  disease  germs. 

Hematinics  improve  the  quality  of  the  blood  by  in- 
creasing the  proportion  of  hematin  (coloring  matter). 

Hematopoietics  promote  the  processes  of  blood-making. 

Hemostatics  are  agents  arresting  internal  hemorrhage. 

Hypnotics  are  drugs  producing  sleep  without  suspend- 
ing the  consciousness  of  pain. 


476       SQUIBB'S  MATERIA  MEDICA 

Intestinal  Astringents  constrict  the  intestinal  mucous 
membrane  and  in  consequence  arrest  or  diminish  diarrhea. 

Laxatives  are  mild  cathartics.     See  under  cathartics. 

Lenitives  are  gentle  laxatives;  aperients. 

Lithonlriptics  are  agents  supposed  to  promote  the  solu- 
tion of  concretions  in  the  excretory  passages. 

Masticatories  are  drugs  intended  for  chewing  to  in- 
crease the  secretion  of  saliva. 

Motor  Depressants  decrease  the  functional  activity  of 
the  spinal  cord  and  other  motor  centers,  and  in  sufficiently 
large  doses  paralyze  them. 

Motor  Excitants  increase  the  activity  of  the  spinal 
cord  and  other  motor  centers,  producing  disturbances  of 
motility,  increased  reflex  excitability,  and  tetanic  convul- 
sions when  given  in  large  doses,  the  end  effect  being 
motor  paralysis  from  overstimulation. 

Mydriatics  cause  dilatation  of  the  pupils   (mydriasis). 

Myotics  produce  contraction  of  the  pupils  (myosis). 

Narcotics  are  drugs  that  produce  stupor,  coma,  in- 
sensibility, and  finally  death  from  paralysis  of  the  medul- 
lary centers,  according  to  the  doses  given. 

Nervines  are  remedies  used  in  nervous  diseases. 

Nutrients  are  nutritious  substances  or  foods. 

Oxytocics  are  drugs  promoting  uterine  contractions  and 
thus  hastening  parturition. 

Parasiticides  inhibit  the  growth  of  or  kill  parasites 
found  upon  the  body;  Antiparasitics. 

Parturients  or  Parturifacients  induce  or  facilitate  birth. 

Peristaltics  are  agents  stimulating  or  increasing  the 
vermicular  action  of  the  intestines. 

Proteclives  are  substances  spread  over  an  injured  part 
or  other  lesion,  mechanically  protecting  it  from  the  air, 
moisture,  or  friction. 

Proteolytics  are  solvents  or  digestants  of  proteins. 

Purgatives  are  rather  powerful  cathartics. 

Reconstructives  or  Restoratives,  aid  in  the  rebuilding 
of  lost  tissue,  by  promoting  constructive  metamorphosis. 

Refrigerants  are  agents  having  cooling  and  slightly 
febrifuge  properties. 

Resolvents  are  systemic  remedies  favoring  the  absorp- 
tion of  exudates  or  tumors. 

Respiratory  Depressants  lower  the  activity  of  the  res- 


SQUIBB'S  MATERIA  MEDICA       477 

piratory  center,  rendering  the  respirations  slow  and 
shallow. 

Respiratory  Stimulants  increase  the  activity  of  the  res- 
piratory center,  accelerating  and  deepening  the  res- 
pirations. 

Rubefacients  redden  the  skin  and  hence  act  as  counter- 
irritants. 

Sedatives  are  medicaments  allaying  irritability  of  an 
organ  or  nerve  center. 

Slalagogues  are  drugs  increasing  the  secretion  of  saliva. 

Soporifics  are  mild  hypnotics. 

Sternutatories  are  drugs  that  produce  sneezing  when 
applied  to  the  nasal  mucous  membrane. 

Stimulants  increase  functional  activity  or  some  trophic 
or  functional  process;  alcoholics  are  commonly  called 
stimulants  in  a  general  sense. 

Stomachics  are  medicaments  which  stimulate  gastric 
digestion  and  restore  tone  to  the  stomach. 

Styptics  are  agents  arresting  bleeding  by  their  local 
application. 

Sudorifics  are  drugs  that  induce  profuse  perspiration ; 
energetic  diaphoretics. 

Teniacides  and  Teniafuges  are  worm-destroyers  and 
worm-expellers  respectively. 

Tonics  (General)  are  remedies  improving  the  general 
condition  of  the  system. 

Uterine  Tonics  are  supposed  to  impart  tone  to  the 
uterine  system. 

Vasoconstrictors  contract  the  bloodvessels,  lessening 
the  circulation  therein  and  raising  blood  pressure. 

Vasodilators  produce  dilatation  of  the  peripheral 
bloodvessels  and  increase  the  circulation  therein,  thus 
tending  to  relieve  internal  congestions. 

Vermicides  are  worm  annihilators. 

Vesical  Sedatives  lessen  irritability  of  the  bladder, 
quiet  pain  in  that  organ  and  lessen  desire  to  urinate. 

Vesical  Tonics  improve  the  tone  of  the  bladder  by  in- 
creasing the  contractile  power  of  its  muscular  fibers,  thus 
preventing  both  retention  of  urine  and  incontinence. 

Vesicants  are  blistering  agents ;  epispastics. 

Vulneraries  are  agents  employed  for  healing  wounds. 


478        SQUIBB'S  MATERIA  MEDICA 


The  Metric  System 

In  view  of  the  fact  that  the  metric  system  of  weights  and 
measures  is  now  used  in  the  U.  S.  Pharmacopoeia  and 
the  National  Formulary,  to  the  exclusion  of  all  others,  a 
brief  description  of  the  system,  supplemented  by  tables 
of  equivalents,  will  no  doubt  be  of  interest  to  many  who 
are  unfamiliar  with  it. 

The  starting  point  of  the  metric  system  of  weights  and 
measures  is  the  meter,  the  unit  of  linear  measure,  repre- 
senting one  ten-millionth  of  the  polar  quadrant  of  the 
earth — that  is,  the  distance  from  the  equator  to  the  poles 
— and  equivalent  to  39.37  English  inches. 

The  gramme  is  the  unit  of  weight.  It  is  derived  as 
follows:  the  meter  is  divided  into  one  hundred  equal  parts 
(centimeters)  ;  upon  one  such  part,  or  centimeter,  as  a 
base  a  cube  is  erected  having  for  its  three  dimensions  one 
centimeter  each.  The  contents  of  this  are  one  cubic  centi- 
meter, which  quantity  of  distilled  water  at  its  maximum 
density  and  30  inches  barometric  pressure  weighs  one 
gramme,  or  15.432  grains;  and  1000  cubic  centimeters 
(or  mils)  make  one  liter,  or  33.81  fluidounces.  One 
liter  of  distilled  water  at  its  maximum  density  and  30 
inches  barometric  pressure  weighs  1  000  grammes,  or  one 
kilogramme,  or  2.2  pounds  avoirdupois. 

The  denominations  representing  the  subdivisions  of  any 
unit  are  expressed  by  prefixing  the  Latin  numerals  deci, 
centi,  and  milli  to  the  unit — meaning  respectively  one- 
tenth,  one-hundredth,  and  one-thousandth.  The  multi- 
ples are  expressed  by  prefixing  the  Greek  numerals  delfa, 
hecto  and  £i'/o — meaning  respectively  ten,  one  hundred 
and  one  thousand. 

For  the  use  of  those  not  familiar  with  the  metric  or 
decimal  system,  as  it  is  also  called,  we  append  a  few 
tables  of  equivalents.  The  values  given  in  these  tables 
are  necessarily  approximate,  and  hence  should  not  be 
taken  as  units  from  which  multiples  can  be  made  at  liberty 
and  exact  results  obtained.  For  instance,  0.2  gramme 
is  given  as  the  equivalent  of  3  grains;  300  grains,  how- 
ever, would  not  be  quite  1 00X0.2  gramme  or  20 
grammes,  but  19.43  grammes. 


SQUIBB'S  MATERIA  MEDICA        479 

The  usual  abbreviations  and  exact  equivalents  of  the 
metric  units  are  as  follows: 


M.  =meter                =       1  .  09361  yards  = 
dm.  =  decimeter         =       0.10936      "      = 
cm.  =  centimeter        =       0.01093      "      = 
mm.  =millimeter        =       0.00109     ' 

3.28083ft.  =39.37 
0.32808  "  =   3.937 
0.03280  "  =   0.3937 
0.00328  "  =   0.03937 

in. 

Kg.  =kilogramme     =  1000             Gm. 
Gm.  =  gramme            =       1 
dg.  =decigramme     =       0.1 
eg.  =  centigramme   =       0.01 
mg.  =  milligramme    =       0.001          " 

=  15432.356     grains 
15.4324       " 
1.5432       " 
=          0.1543 
0.01543     " 

1.  =liter  =1000  mils.  =2.1134    pints  =  33. 8148  fl.  ozs. 

dl.  =  deciliter  =   100    "  =0.2113        "     =   3.381 

ml.  =milliliter  or  mil  =       1  mil.  =0.03381  fl.  oz.  =  16. 231    min. 

(formerly  cubic  centimeter  or  Cc.) 


Metric  Weight  and  Apothecaries'  Equivalents 


Gramme 

Grain 

Gramme  Grains 

Grammes 

Grains 

Grammes 

Grains 

0.001 

ta 

1/64 

0.04 

_ 

2/3 

0.6 

— 

9 

10.     = 

154.3 

0.0015 

r* 

1/40 

0.05 

= 

3/4 

0.65 

« 

10 

15.     = 

231.3 

0.002 

= 

1/32 

0.065 

= 

1 

0.7 

= 

10.8 

20.     = 

308.6 

0.003 

= 

1/20 

0.08 

=3 

H/4 

0.8 

= 

12 

25.     = 

385.8 

0.004 

= 

1/16 

0.1 

= 

H/2 

1.0 

= 

15.432 

30.     = 

463 

0.005 

= 

Vl2 

0.15 

= 

21/4 

1.5 

tm 

23 

40.    = 

617.3 

0.006 

= 

1/10 

0.2 

= 

3 

2. 

= 

30.8 

50.     = 

771.6 

0.008 

= 

1/8 

0.25 

= 

4 

4. 

83 

61.5 

60.    = 

926 

0.01 

= 

1/6 

0.3 

= 

41/2 

5. 

= 

77 

0.015 

= 

1/4 

0.4 

= 

6 

6. 

= 

92.5 

0.03 

_ 

1/2 

0.5 

= 

71/2 

8. 

=  123.4 

Metric  Weight  and  Its  Avoirdupois  Equivalents 


Grammes 

Grammes 

Grammes 

25.      =           385.8  grs. 

(approx.  7/g  oz.) 
28.35=1  oz.  =437.5  grs 
30.      =  1  oz.  +  25     grs 
32.      =  1  oz.  +  56     grs 
33.      =1  oz.+  72     grs 
34.      =  1  oz.  +  87     grs 
35.      =loz.+103     grs 
36.      =loz.+118     grs 
40.      =loz.+180     grs 
45.      =loz.  +218     grs 
50.      =  loz.+334    grs 

60.  =  2  oz.  +    50  grs. 
70.  =  2  oz.  +  205  grs. 
75.  =  2  oz.  +  282   grs. 
80.  =  2  oz.  +  360  grs. 
90.  =  3  oz.  +    76  grs. 
100.  =  3  oz.  +  231  grs. 
(approx.  31/2  oz.) 
120.  =  4  oz.  +  102  grs. 
125.  =  4  oz.  +  179  grs. 
150.  =5  oz.  +  127  grs. 
200.  =  7  oz.  +    24   grs. 
250.  =  8  oz.  +  358  grs. 

300.  =10  oz.  +255  grs. 
400.  =  14  oz.  +  48  grs. 
500.  =17  oz.  +279  grs. 

(approx.  1  ft.,  1%  oz.) 
600.  =21  oz.+  72  grs. 
700.  =24  oz.  +303  grs. 
750.  =26  oz.  +198  grs. 
800.  =28  oz.  +  96  grs. 
900.  =31  oz.  +326  grs. 
1000.  =35oz.  +120  grs. 
(approx.  21  la  Ibs.) 

480        SQUIBB'S  MATERIA  MEDICA 


Metric  Measure  and  Its  Equivalents  in  Apothecaries' 
Measure 


Mils 

Mils 

Mils 

0.06=   1       minim 

6  =  1.62  fluidrachms 

120  =   4       fluidouncet 

0.1    =   1.5    minims 

8  =  2.16 

150=   5 

0.2    =  3 

10  =  2.71 

200=   6.75 

0.3    =  5 

15  =4 

300=10.14 

0.4    =  6 

20  =  5.42 

400=13.53 

0.5    =  8 

25  =  6.75 

473=16.00         "(Ipt) 

0.6    =10 

30  =  1       fluid 

ounce 

500=16.90 

0.7    =11 

40  =1.3     fluidc 

unces 

600  =20.30 

0.8    =12 

45  =  1.5 

700  =23.67 

0.9    =14 

50  =  1.7 

750=25.36 

1       =16.23 

60  =  2 

800  =27.              " 

2       =32.46 

70  =  2.3 

900=30.43 

3       =48.69 

75  =  2.53 

1000  =33.81 

4       =64.92 

90  =  3. 

(=  1  liter) 

5       =    1.35  fluidrachms 

100  =  3.38 

Apothecaries'  Weight  and  Metric  Equivalents 


Gramme 

Grammes 

Grammes 

I'lOO  grain    =   0.0006 

2     grains              =0.13 

11  '2  drachms    =     5.85 

1/64 

=   0.001 

3 

=  0.2 

13/4 

=     6.81 

1/50 

=   0.0013 

4 

=  0.26 

2 

=     7.78 

1/40 

=   0.0016 

5 

=  0.32 

21/2 

=     9.72 

1/32 

=   0.002 

6 

=  0.39 

3 

=   11.65 

1/20 

=   0.003 

8 

=  0.52 

4 

=  15.55 

1/16 

=   0.004 

10 

=  0.65 

5 

=   19.43 

1/12 

=   0.005 

12 

=  0.78 

6 

=   23.3 

1/10 

=   0.006 

15 

=  0.97 

loz.«'480grs.)  =   31.1 

1/8 

=   0.008 

15.4 

=  1. 

2  ounces 

=   62.2 

1/3 

=   0.011 

20 

=  1.3 

3 

=   93.3 

Vo 

=   0.012 

24 

=  1.55 

4 

=  121.4 

1/4 

=   0.015 

30 

=1.94 

6 

=  186.6 

1/3 

=   0.022 

to 

=  2.6 

8 

=248.8 

1/2 

=   0.032 

15 

=2.92 

10 

=  311. 

3/L.    - 

=   0.048 

50 

o   OQ 
—  i>.i,o 

12 

=  373.2 

1. 

=  0.065 

60  grs.  or  1  dnn.  =3.S9 

Apothecaries'   Measure  and   Metric   Equivalents 


1  minim  =0.06  mil        60 

minims  or  1  fluidrachm         = 

3.70  mi 

2  minims  =0.12 

11/4  fluidrachms 

4.65 

3 

=  0.18 

1  "2 

= 

5.60 

4 

=  0.25 

13,4 

6.50 

5 

=  0.31 

2 

= 

7.50 

6 

=  0.37 

3 

11.25 

7 

=  0.43 

4 

1  5.00 

8 

=  0.49 

8 

fluidraohms  or  1  fluidounce  = 

30.00 

9 

=  0.55 

(more  exactly, 

29  57) 

10 

=  0.61 

2 

fluidounces 

= 

59.15 

15 

=0.92 

-   3 

" 

88.72 

20 

=  1.23m 

is 

4 

fluidounces 

= 

118.29 

25 

=  1.54 

8 

" 

= 

236.59 

30 

=  1.84 

16 

fluidounces  or  (1  pint) 

473.17 

40 

=  2.45 

32 

f'.uidounces 

= 

946.33 

45 

=  2.79 

128 

fluidounces  or  1  gallon 

=  3785.33 

50        "       =3.08     ' 

SQUIBB'S  MATERIA  MEDICA       481 

Avoirdupois  Weight  and  Metric  Equivalents 
1  AT.  Oz.   •-  437.5  Grains 


1/8  oz.  =   3.54  G 
1/4  oz.  =   7.09 
1/2  oz.  =  14.17 
1   oz.  =  28.35 
2   ozs.  =  56.70 
3   ozs.  =  85.05 
4   ozs.  =  113.40 
5   ozs.  =  141.75 
6   ozs.  =  170.10 

m. 

7  ozs.  =  198.45  G 
8  ozs.  =  226.80 
9  ozs.  =  255.15 
10  ozs.  =  283.50 
11  ozs.  =  311.84 
12  ozs.  =  340.20  ' 
13  ozs.  =  368.54 
14  ozs.  =  396.90 
15  ozs.  =  425.25 

m. 

1  Ib.  =  453.60  Gn 

2  Ibs.  =  907.18 
2.2  Ibs.  =  1000.00 
3  tbs.  =  1360.78 
4  Ibs.  =  1814.37 
5  Ibs.  =  2267.96 
6  Ibs.  =  2721.55 
8  Ibs.  =  3628.74 
10  Ibs.  =  4535.92 

Thermometric  Equivalents 

Fahrenheit  and  Centigrade  Scales 

RULES. — To  reduce  Centigrade  degrees  to  those  of 
Fahrenheit,  multiply  by  9,  divide  by  5,  and  add  32. 

To  reduce  Fahrenheit  degrees  to  those  of  the  Centi- 
grade scale,  subtract  32,  multiply  by  5,  and  divide  by  9. 

1°  of  the  Centigrade  scale  is  equal  to  1.8°  of  the 
Fahrenheit  scale,  and  1  °  of  the  Fahrenheit  scale  is  equal 
to  0.555  or  5/9°  of  the  Centigrade  scale. 


°C.       °F. 

°C.        "P. 

°C.        CF. 

°C.      »P.   i  °C.      °F.   j  °C.       °F. 

-25 

-13.0 

-  1 

30.2 

23 

73.4 

47 

116.6 

71 

159 

8    95 

203 

-24 

-11.2 

0 

32 

24 

75.2 

48 

118.4 

72 

161 

6    96 

204.8 

-23 

-  9.4 

1 

33.8 

25 

77 

49 

120.2 

73 

163 

4    97 

206.6 

-22 

-  7.6 

2 

35.6 

26 

78.8 

50 

122 

74 

165 

2j   98 

208.4 

-21 

-   5.8 

3 

37.4 

27 

80.6 

51 

123.8 

75 

167 

99 

210.2 

-20 

-  4 

4 

39.2 

28 

82.4 

52 

125.6 

76 

168 

8100 

212 

-19 

-  2.2 

5 

41 

29 

84.2 

53 

127.4 

77 

170 

6  101 

213.8 

-18 

-  0.4 

6 

42.8 

30 

86 

54 

129.2 

78 

172 

4  102 

215.6 

—17 

1.4 

7 

44.6 

31 

87.8 

55 

131 

79 

174 

2  103 

217.4 

-16 

3.2 

8 

46.4 

32 

89.6 

56 

132.8 

80 

176 

104 

219.2 

-15 

5 

9 

48.2 

33 

91.4 

57 

134.6 

81 

177 

8  105 

221 

-14 

6.8 

10 

50 

34 

93.2 

58 

136.4 

82 

179 

6  106 

222.8 

-13 

8.6 

11 

51.8 

35 

95 

59 

138.2 

83 

181 

4^107 

224.6 

-12 

10.4      12 

53.6 

36 

96.8 

60 

140 

84 

183 

2  108 

226.4 

-11 

12  .  2      13 

55.4 

37 

98.6 

61 

141.8 

85 

185 

109 

228.2 

-10 

14 

14 

57.2 

38 

100.4 

62 

143.6 

86 

186 

8  110 

230 

-  9 

15.8      15 

59 

39 

102.2 

63 

145.4 

87 

188 

6  111 

231.8 

-  8 

17.61     16 

60.8 

40 

104 

-64 

147.2    88 

190 

4  112 

233.6 

-   7 

19.  4j     17 

62.6 

41 

105.8 

65 

149        89 

192 

2  113 

235.4 

-  6 

21.2      18 

64.4 

42 

107.6      66 

150.8    90 

194 

114 

237.2 

-   5 

23          19 

66.2 

43 

109.4 

67 

152.6    91 

195.8115 

239 

—  4 

24.8      20 

68 

44 

111.2 

68 

154.4    92 

197 

6  116 

240.8 

-  3 

26.6 

21 

69.8 

45 

113 

69 

156.21   93 

199 

4117 

242.6 

-   2 

28.4      22 

71.6 

46 

114.8 

70 

158 

94. 

201 

2  118 

244.4 

482        SQUIBB'S  MATERIA  MEDICA 
Practical  Urinalysis 

For  the  Medical  Practitioner 


We  give  below  a  short  practical  talk  on  the  every-day 
analysis  of  urine  which  the  practicing  physician  is  regularly 
called  upon  to  perform.  We  have  selected  only  such  tests 
as  a-re  easy  of  application  and  reliable. 

Normal  urine  has  an  amber  color,  a  slight  acid  reaction, 
a  peculiar  nondescribable  odor,  and  a  bitter  saline  taste. 
Its  specific  gravity  varies  from  1.010  to  1.030  at  25°C. 
and  the  average  quantity  excreted  in  twenty-four  hours  is 
1,500  mils  or  Cc.  (about  50  fl.  ozs.),  1,000  parts  of 
healthy  urine  contains  about  40  parts  of  solid  matter,  con- 
sisting chiefly  of  urea  (23  parts),  sodium  chloride  (1  1 
parts),  phosphoric  acid  chiefly  as  phosphates  (2.3  parts), 
sulphuric  acid  mainly  as  sulphates  (1.3  parts),  uric  acid 
(0.5  part),  hippuric  acid,  leukomaines,  urobilin,  and  or- 
ganic salts. 

The  specific  gravity  of  any  specimen  of  urine  can  be 
conveniently  and  accurately  determined  by  the  use  of 
Squibb's  Specific  Gravity  Apparatus.  This  is  supplied 
in  a  case  containing  a  certified  hydrometer,  a  thermometer, 
a  glass  jar  and  a  tube  of  litmus  paper. 

The  amount  of  total  solids  can  be  roughly  estimated  by 
Haser's  method.  This  consists  in  multiplying  the  last  two 
figures  of  the  specific  gravity  by  2.33.  For  example,  if 
the  specific  gravity  is  1.020,  multiply  20  by  2.33,  which 
gives  46.6  Gm.,  the  amount  of  total  solids  in  each  1 ,000 
mils  (Cc.),  of  the  urine.  If  a  person  voids  1,500  mils 
(Cc.)  of  urine  daily  the  total  amount  of  solids  eliminated 
therewith  is  46.6  x  1 .5,  or  69.9  Gm. 

The  quantity  of  urea  eliminated  can  be  quickly  and 
accurately  estimated  by  the  use  of  Urease  Squibb.  Com- 
plete information  on  this  product  will  be  found  among  the 
scientific  notes  at  the  end  of  this  book. 

Squibb' s  Urea- Apparatus  will  also  be  found  convenient 
for  the  purpose.  Complete  directions  accompany  the  out- 
fit. 

The  abnormal  constituents  found  in  various  patholog- 
ical urines  are  albumin,  sugar,  acetone,  bile,  indican, 
blood,  casts,  pus,  spermatozoa,  and  epithelial  cells. 


SQUIBB'S  MATERIA  MEDICA       483 

In  testing  urine  clean  test  tubes  and  fresh  reagents  are 
essential.  A  separate  pipette  should  be  used  for  each 
solution  employed.  (See  list  of  Test  Solutions,  Part  IV 
of  this  book.) 


Albumin  Tests 

If  the  urine  is  cloudy,  it  should  be  filtered  through  filter 
paper — not  talcum,  fuller's  earth,  magnesium  carbonate 
or  charcoal;  before  testing  it  for  albumin  freshly  voided 
urine  should  be  allowed  to  cool,  and  no  specimen  of 
urine  to  which  the  heat  test'  has  been  applied  should  be 
used  for  the  nitric  acid  contact  test.  The  first  two  tests 
are  approved  by  the  Association  of  Life  Insurance  Med- 
ical Directors  and  employed  by  the  medical  examiners. 

HEAT    TEST 

If  the  urine  is  acid,  take  one-half  test-tube  of  the  filtered 
urine,  add  one-sixth  of  its  volume  of  saturated  salt  solu- 
tion (five  ounces  to  the  pint),  hold  the  tube  by  the  lower 
portion  and  boil  the  upper  one-third.  If  a  cloud  forms  it 
consists  of  either  albumin  or  earthly  phosphates.  Add 
two  or  three  drops  of  diluted  nitric  acid,  boil  again,  and 
add  three  drops  more  of  the  acid;  if  the  cloud  remains 
albumin  is  present,  but  if  the  cloud  entirely  disappears  the 
precipitate  is  phosphatic  and  albumin  is  absent. 

If  the  urine  is  alkaline  or  neutral,  take  one-half  test- 
tube  of  the  filtered  urine,  add  one-sixth  of  its  volume  of 
saturated  salt  solution  and  then  a  sufficient  number  of 
drops  of  diluted  nitric  acid,  or  of  33  per  cent,  acetic  acid, 
to  render  faintly  acid.  This  must  be  done  in  all  cases 
where  the  urine  is  alkaline  or  neutral,  for  albumin  will  not 
be  precipitated  from  such  urine  by  heat.  When  this  has 
been  done  apply  heat  as  directed  in  the  preceding 
paragraph. 

NITRIC  ACID  CONTACT  TEST  (HELLER'S  TEST) 
Take  a  perfectly  clean  and  dry  test-tube  having  caliber 
of  about  one  inch  (a  conical  wineglass  is  preferable),  and 
place  into  it  about  one  inch  of  urine;  allow  concentrated 
rtitric  acid  to  flow  slowly  from  a  pipette  down  the  side  of 
the  inclined  test-tube  underlying  the  urine.  Wait  five  min- 
utes. By  use  of.  dark  background  look  very  closely  for 


484        SQUIBB'S  MATERIA  MEDICA 

white  band  or  cloud  of  albumin  just  above  junction  of 
acid  and  urine. 

Or,  place  into  a  test-tube  of  large  diameter  about  one 
inch  of  concentrated  nitric  acid,  then  incline  the  tube  and 
from  a  pipette  allow  an  equal  volume  of  urine  to  flow 
slowly  down  the  side  of  the  tube,  carefully  overlaying  the 
acid.  If  albumin  is  present,  by  the  use  of  a  dark  back- 
ground a  zone  will  be  seen  just  above  the  point  of  contact 
of  the  urine  and  the  acid,  the  intensity  of  the  cloud  de- 
pending on  the  amount  of  albumin  present.  If  no  cloud 
is  seen,  the  tube  should  be  set  aside,  and  re-examined  in 
one-half  hour,  because  the  reaction  for  albumin  is  some- 
times slow. 

(NOTE: — U rates  and  copaiba  and  some  other  resins 
may  give  a  white  ring.  The  former  are  dissolved  on  heat- 
ing; the  latter,  by  the  addition  of  alcohol.  Albumin  is 
not  affected  by  either  treatment.) 

ESBACH'S  PICRIC  ACID  TEST 

Drop  the  urine  into  a  clear  quantity  of  Esbach's  re- 
agent made  as  follows : 

Picric  Acid 1  Gm. 

Citric  Acid 2  Gm. 

Distilled  Water  q.  s.  ad 1  00  mils 

A  white  precipitate  or  cloud  forms  if  albumin  is  present. 
For  the  quantitative  estimation  of  albumin,  an  Esbach's 
albuminometer  proves  very  serviceable.  It  is  inexpensive 
and  simple  of  manipulation. 


Tests  for  Sugar 

In  testing  for  sugar,  if  the  urine  has  been  found  to  con- 
tain more  than  a  faint  trace  of  albumin  the  latter  should 
first  be  removed  by  boiling  and  filtering. 

FEHLING'S  TEST 

Mix  equal  parts  of  the  copper  sulphate  and  alkaline 
tartrate  solutions  in  a  test  tube  and  add  a  quantity  of  water 
equal  to  the  combined  volume  of  the  two  reagents  used; 
the  total  quantity  to  prepare  for  a  test  need  not  exceed 
5  mils  (Cc.).  Boil  the  mixture.  If  it  remains  clear,  it 


SQUIBB'S  MATERIA  MEDICA       485 

shows  that  the  Fehling's  solution  is  in  good  condition. 
Now  add  a  few  drops  of  the  urine;  warm  the  mixture  but 
do  not  boil,  and  add  a  few  more  drops  of  the  urine ;  warm 
again,  and  so  on  until  the  amount  of  urine  added  equals 
one-half  the  volume  of  test  solution  used.  If  the  specific 
gravity  of  the  urine  to  be  tested  is  below  1 .020  the  urine 
may  be  added  in  equal  volume  to  the  test  solution.  If 
sugar  is  present,  a  yellow  or  red  precipitate  of  suboxide  of 
copper  appears.  This  occurs  quickly  if  much  sugar  is 
present.  If  the  amount  of  sugar  is  less  than  one  percent, 
the  reduction  will  not  appear  until  after  several  minutes — 
five  to  thirty.  If  a  reduction  does  not  take  place  in  thirty 
minutes  sugar  is  absent;  if,  on  the  other  hand,  the  result 
of  the  test  is  still  doubtful,  the  test  tube  should  be  set  aside 
from  twelve  to  eighteen  hours  and  then  the  sediment  ex- 
amined to  see  if  there  has  been  any  deposit  of  the  suboxide 
of  copper. 

(NOTE. — We  also  furnish  Fehling's  Test  Solution 
Elements  complete  for  executing  the  test,  and  for  the  ap- 
proximate quantitative  determination  of  sugar.) 

HAINES'S  TEST 

Put  1  fluidrachm  of  Haines's  Test  Solution  Squibb  into 
a  test  tube  and  boil  gently ;  add  8  to  1 0  drops  of  the 
suspected  urine  and  again  boil  gently.  If  sugar  is  present, 
a  copious  yellow  or  yellowish- red  precipitate  of  copper 
suboxide  separates;  if  the  amount  of  sugar  in  the  urine  is 
small  the  reduction  may  require  from  five  to  thirty  minutes, 
but  if  no  change  has  taken  place  in  thirty  minutes  sugar  is 
absent.  If  the  result  of  the  test  is  still  doubtful,  the  test 
tube  should  be  set  aside  and  allowed  to  stand  from  twelve 
to  eighteen  hours  and  then  the  deposit  examined  for  the 
presence  of  a  suboxide  of  copper. 

(NOTES. — A  grayish  or  greenish  precipitate  of  phos- 
phates which  almost  always  forms  through  the  action  of 
the  alkali  in  Fehling's  or  Haines's  solution,  should  not  be 
mistaken  for  a  deposit  of  suboxide  of  copper,  which  is  al- 
ways yellow  or  red.  Simple  decolorization  of  either  Feh- 
ling's or  Haines's  solution  by  the  urine  should  not  be  con- 
sidered a  positive  reaction  for  sugar,  for  sometimes  a  con- 


486        SQUIBB'S  MATERIA  MEDICA 

centrated  and  strongly  acid  urine  which  is  sugar-free,  will 
decolorize  the  copper;  on  the  other  hand,  a  decolorization 
may  indicate  a  beginning  reduction  of  the  copper,  particu- 
larly when  only  a  trace  of  sugar  is  present.  Under  such 
circumstances  it  is  advisable  to  let  the  test  tube  stand  for 
twelve  to  eighteen  hours,  before  arriving  at  a  definite 
conclusion.  In  testing  for  traces  of  sugar,  when  the  tube 
is  set  aside  it  is  well  to  dilute  the  contents  with  about  2 
volumes  of  water.  This  reduces  the  density  of  the  solu- 
tion, and  enables  any  cuprous  oxide  to  subside  that  might 
otherwise  remain  in  suspension. 


Tests  for  Acetone 

LANGE'S  TEST 

Mix  15  mils  (Cc.)  of  the  urine  with  0.5  to  1  mil  of 
acetic  acid,  and  add  a  few  drops  of  freshly  prepared  con- 
centrated solution  of  sodium  nitroprusside.  Overlay  with 
ammonia  water.  At  the  point  of  contact  a  violet  ring 
forms. 

LIEBEN'S  TEST 

Distill  a  portion  of  the  urine  after  adding  a  few  drops 
of  phosphoric  acid.  To  the  distillate  in  a  test  tube  add  a 
few  drops  of  compound  solution  of  iodine  (Lugol's  solu- 
tion) and  then  sufficient  solution  of  potassium  hydroxide 
to  render  the  mixture  decidedly  alkaline.  A  yellow  pre- 
cipitate consisting  of  iodoform  will  at  once  form  if  acetone 
is  present. 


Tests  for  Bile  Pigments 

GMELIN'S  TEST 

Add  fuming  nitric  acid  to  the  urine  contained  in  a  test 
tube,  by  inclining  the  same  and  pouring  down  the  side 
slowly;  the  acid  will  form  a  layer  under  the  urine.  If  bile 
pigment  is  present  colored  rings  form  near  the  junction  of 
the  two  liquids ;  a  green  ring  above,  and  under  this  a  blue, 
violet-red,  and  reddish  yellow.  If  the  green  and  violet 
red  rings  are  wanting,  it  indicates  the  probable  presence 
of  lutein. 


SQUIBB'S  MATERIA  MEDICA        487 

(NOTE. — Fuming  nitric  acid  may  be  prepared  by  add- 
ing a  few  drops  of  formaldehyde  solution  to  regular  nitric 
acid  and  carefully  warming  until  it  assumes  a  red  color.) 

ROSSBACH'S  TEST 

Filter  the  urine  through  filter  paper.  After  it  has  all 
passed  through,  apply  a  drop  of  nitric  acid  to  the  filter. 
A  pale-red  spot  will  be  formed,  surrounded  by  red,  violet, 
blue,  and  green  circles. 

HELLER'S  TEST 

Pour  about  5  mils  (Cc.)  of  concentrated  hydrochloric 
acid  into  a  test  tube  and  add  enough  urine  to  impart  a 
color  to  it.  Then  carefully  pour  nitric  acid  down  the 
side  of  the  tube  so  as  to  form  a  layer  on  the  bottom.  A 
play  of  colors  at  the  junction  of  the  two  layers  indicates 
bile  pigments. 

Tests  for  Indican 

MCMUNN'S  TEST 

Boil  about  5  mils  (Cc.)  of  the  urine  with  an  equal 
volume  of  hydrochloric  acid  and  a  few  drops  of  nitric 
acid.  Allow  to  cool,  then  shake  with  2  or  3  mils  of 
chloroform.  The  latter  becomes  colored  violet. 

JAFFE'S  TEST 

Mix  10  mils  (Cc.)  of  the  urine  with  an  equal  amount 
of  concentrated  hydrochloric  acid  and  2  or  3  mils  of 
chloroform ;  add  solution  of  chlorinated  soda  drop  by 
drop,  shaking  after  each  addition.  The  chloroform  will 
gradually  become  colored  blue.  Slight  excess  of  the  soda 
solution  will  cause  no  harm,  but  a  large  excess  may  inter- 
fere with  the  test. 


Blood  Tests 

ROBERTS'S  OCCULT  BLOOD  TEST 

Blood  may  be  conveniently  detected  by  means  of  Dr. 
Dudley  Roberts's  Occult  Blood  Test  Tablets,  described 
in  the  Tablet  section  of  this  book.  The  microscopic  and 
spectroscopic  tests  are  also  very  satisfactory. 


488        SQUIBB'S  MATERIA  MEDICA 

GUAIAC  TEST     • 

Mix  equal  volumes  of  fresh  tincture  guaiac  and  "ozon- 
ized" oil  of  turpentine  (that  is,  old  turpentine  oil  that  has 
been  exposed  to  the  air  and  sunlight  for  some  time),  and 
cautiously  overlay  the  mixture  on  the  urine  contained  in  a 
test  tube.  At  the  junction  of  the  two  layers  a  grayish 
precipitate  forms  and  immediately  above  it  a  blue  ring  if 
blood  is. present.  On  agitation  the  entire  mixture  turns 
blue.  Pus  may  give  the  same  reaction,  but  the  blue  ring 
disappears  on  boiling ;  not  so  with  blood. 


Detection  of  Pus 

The  best  means  of  detecting  pus  is  the  microscope. 
However,  the  following  test  is  often  employed:  Let  the 
urine  settle  in  a  conical  graduate.  Pour  off  the  superna- 
tant liquid  from  the  sediment.  Add  to  the  latter  a  few 
drops  of  concentrated  solution  of  potassium  or  sodium 
hydroxide,  and  stir.  Pus  becomes  colored  greenish,  and 
gelatinizes  to  a  tough  mass.  (Mucus  is  partly  dissolved 
by  this  treatment,  with  the  formation  of  a  flocculent  pre- 
cipitate.) 


Uric  Acid  and  Urate  Tests 

Strongly  acidulate  the  urine  with  hydrochloric  acid 
and  set  aside  for  24  hours.  Yellowish-red  crystals  of 
uric  acid  will  deposit  on  the  bottom  and  sides  of  the  test 
tube.  By  comparing  this  tube  with  one  containing  a 
similar  quantity  of  normal  urine  treated  in  the  same 
manner,  an  approximate  idea  may  be  obtained  of  the 
amount  of  uric  acid  in  the  abnormal  specimen,  sufficiently 
accurate  for  ordinary  practical  purposes. 

The  murexide  or  Weidel's  test  is  conducted  by  evap- 
orating to  dryness  a  few  drops  of  the  urine  in  a  watch 
glass  or  porcelain  capsule,  adding  a  drop  or  two  of  nitric 
acid,  again  evaporating  carefully  and  then  adding  one  or 
two  drops  of  ammonia  water.  Murexide  (ammonium 
purpurate)  will  be  formed,  and  be  shown  by  a  purple 
coloration. 


SQUIBB'S  MATERIA  MEDICA       489 


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492        SQUIBB'S  MATERIA  MEDICA 
Obstetric  Calendars 


To  use  this  obstetric  calendar  of  Dr.  WlLLIAM  L. 
CANTON,  New  York  City,  take  the  date  of  the  beginning 
of  the  last  menstruation,  add  to  it  the  number  in  the  circle 
which  accompanies  the  name  of  the  month  in  which  it  oc- 
cucred,  and  to  the  sum  prefix  the  name  of  the  month  next 
occurring  in  the  same  circle,  going  around  the  circle  in  the 
direction  taken  by  the  hands  of  a  watch.  This  date  is 
the  day  on  which  labor  should  occur.  For  example: 

May  20+4=24+Feb.=Feb.   24 
Sept.     4+7=ll+June=June    11 

If  the  sum  of  the  numbers  carries  the  date  over  into 
the  succeeding  month,  use  such  succeeding  month  to  de- 
termine the  month  of  labor. 

Mar.  30+5=April  4+Jan.=Jan.  4 


SQUIBB'S  MATERIA  MEDICA       493 
SCHULTZE'S  MODIFICATION  OF   NAGELE'S  METHOD 


Subtract  three  months  from  the  date  of  the  beginning 
of  the  last  menstruation,  then  add  to  this  date  the  number 
occurring  in  the  segment  of  the  circle  bearing  the  name 
of  the  latter  month.  If  the  year  is  a  leap  year  add  the 
number  in  parentheses.  The  resulting  date  is  that  on 
which  labor  is  due. 


May  20  —  3  mo.  =  Feb.   20  +  4  =  Feb.  24 

September     4  —  3  mo.  =  June     4  -|-  7  ==  June    1  1 

Mar.   30  —  3   mo.  _  Dec.  30  +  5  =  Jan.      4 


494        SQUIBB'S  MATERIA  MEDICA 

Drugs  that  Affect  the  Color  of  Urine 

Carbolic  Acid  (Phenol)  may  cause  it  to  be  brown. 
Diuretics  and  copious  quantities  of  water  and  other  bever- 
ages cause  urine  to  become  lighter  in  color. 
Methylene  Blue  turns  it  green  if  acid. 
Renal  Irritants  render  it  darker. 

Santonin  makes  it  more  yellow  if  acid,  purple  if  alkaline. 
Senna  may  render  it  red  if  acid,  yellow  if  alkaline. 
Sulphonmethane  (Sulphonal)  may  turn  it  very  dark. 


Drugs  That  Color  the  Stools 

Bismuth  salts  color  them  black  or  very  dark  gray. 
Colchicum  and  its  preparations  tint  them  greenish. 
Iron  and  its  salts  color  them  black.         . 
Mercury  and  its  compounds  make  them  green. 
Purgatives  cause  them  to  be  darker. 


Drugs  Excreted  With  the  Milk 

Arsenic  and  its  compounds.  Opium  and  its  preparations. 

Bromides.  Quinine  and  its  salts. 

Hexamethylenamine.  Sulphur. 

Iodine  and  Iodides.  Vegetable  Cathartics. 

Lead  salts.  Volatile  Oils. 

Mercurials. 


Drugs  That  Often  Cause  Cutaneous  Eruptions 
or  Itching 

Antitoxins  and  Sera.  Copaiba. 

Arsenic  and  its  compounds.  Iodine  and  Iodides. 

Belladonna  and  its  prepa-  Opium  and  Opiates. 

rations.  Quinine  Salts. 

Bromides.  Salicylic  Acid  and  its 
Chloral  Hydrate.  salts. 

Volatile  Oils. 


SQUIBB'S  MATERIA  MEDICA        495 


GRAINS  OF  DRUG  TO  MAKE  A  SOLUTION  CONTAINING 

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PART  VII— SCIENTIFIC  NOTES 


SQUIRE'S  MINERAL  OIL 

Known  as 

Liquid  Petrolatum,  Squibb 

Heavy  (Californian) 


Pure,  Heavy,  Viscous  Mineral  Oil,  Crystal-clear,  OdoT* 

less,  Tasteless,  and  Non-irritating.     An  Efficient, 

Harmless  Intestinal  Evacuant  and  Lubricant. 


For  the  successful  treatment  of  intestinal  stasis  and 
constipation,  the  employment  of  a  mineral  oil  of  correct 
constitution  and  of  highest  purity  is  imperative. 

In  pursuance  of  our  long-established  and  well-known 
policy  to  supply  of  every  product  only  the  best  quality 
for  the  purpose  intended,  we  have  made  a  thorough 
and  exhaustive  study  of  all  American  and  Russian 
mineral  oils  obtainable.  After  more  than  five  years  of  such 
careful  investigation  and  research  we  are  able  to  state: 

First. — There  are  two  distinct  types  of  mineral  oil 
for  internal  use  offered  in  the 


TYPES  OF 
MINERAL  OIL 


market,  differing  greatly  in  physi- 
cal "  and  in  chemical  properties, 
namely: 

(a)  The  light  oils  with  no  characteristic  viscosity. 
They  belong  to  the  methane  or  paraffin  series  of  hydro- 
carbons and  include  not  only  all  the  low  gravity  oils 
of  the  methane  series  which  are  imported  from  Russia 
but  also  all  American  mineral  oils  except  the  Squibb 
Mineral  Oil. 

(&)  The  heavy  oils  of  considerable  viscosity.  They 
consist  principally  of  polymethylenes,  i.e.,  hydrocarbons 
of  the  naphthene  series.  These  are  derived  solely  from 
crudes  found  only  in  certain  parts  of  Russia  and  also 
in  California  which  latter  crude  has  a  naphthene  con- 
tent far  greater  than  any  other  known  crude  in  the  world. 
496 


SQUIBB'S  MATERIA  MEDICA       497 

In  short,  numerous  comparative  tests  made  by  us 
show  the  Californian  heavy  oil  to  differ  in  essential 
respects  from  all  other  American  oils  and  also  to  be 
superior  to  the  Russian  oils. 

We,  therefore,  have  selected  this  Californian  heavy 
oil  of  high  viscosity  as  the  best  mineral  oil  obtainable 
for  the  internal  treatment  of  intestinal  stasis  and  con- 
stipation, and  supply  it  alone  on  all  orders. 

It  is  refined  under  our  control  and  exclusively  for  us 
only  by  the  Standard  Oil  Company  of  California,  which 
has  no  connection  with  any  other  Standard  Oil  Company. 
This     Liquid     Petrolatum    Squibb,     Heavy     (Cali- 
fornian), meets  the  quality  specifications  as  follows: 
li  is  pure;  free  from  paraffins,  inorganic  matter,  organic 
sulphur   compounds   and   all   inju- 
rious hydrocarbons  such  as  anthra- 
cene,  phenanthrene,   chrysene  and 
all  oxidized  acid  and  basic  bodies. 
It  is  colorless,  odorless  and  tasteless. 

It   has    the    Very   High   Specific 
r*        'i 

Gravity 

08g6  toQ  395  at  15o  C     (590  p  ) 

0.881  to  0.890  at  25°  C.  (77°  F.) 


PURITY 


PRAVTTV 
GRAV11Y 


It  has  the  Exceptionally  High  Natural  Viscosity 
571  to  586  Saybolt  at  25°  C.  (77°  F.) 
265  to  278  Saybolt  at  37.7°  C.  (100°  F.) 

or,  according  to  U.S.  P.  standard, 
VISCOSITY  7.0  to  7.6  at  25°  C.  (77°  F.) 

_  I    which  is   over  four  points  higher 
than  the  requirements  of  the  U.  S.  P.  (IX  Revision). 

This  high  viscosity  is  of  supreme  importance  because 
the  clinical  value  of  liquid  petrolatum  is  in  lubrication, 
and  true  viscosity  is  the  index  of  lubricating  power. 

In  selecting  a  mineral  oil  for  internal  use,  it  should  be 
borne  in  mind  that  viscosity  and  specific  gravity  bear 
no  necessary  relation  to  each  other. 

Again  it  should  be  remembered  that  thin  oil  to  which 
paraffin  has  been  added  may  appear  viscous,  but  upon 
testing  it  will  show  itself  to  be  really  a  thin  oil.  A  thin 
oil  never  lubricates  as  well  as  one  that  is  highly  viscous, 
and  an  oil  of  low  viscosity  may  pass  through  the  intestine 


498        SQUIBB'S  MATERIA  MEDICA 

without  producing  any  serviceable  lubrication ;   also  a  thin 
oil  is  apt  to  cause  leakage  or  dribbling. 

Further,  viscosity  diminishes  very  rapidly  as  the  tem- 
perature rises.  This  is  particularly  true  of  all  thin  oils. 
It  is  essential  for  the  physician  to  know  that  the  liquid 
petrolatum  that  he  uses  has  the  necessary  viscosity  at  the 
temperature  of  the  inside  of  the  intestine.  Therefore, 
special  attention  is  called  to  the  particularly  high  and 
efficient  viscosity  of  Liquid  Petrolatum  Squibb,  Heavy 
(Californian)  at  37.7°  C.  (100°  F.).  Also,  this 
viscosity  is  natural;  the  Squibb  ojl  is  not  sophisticated  in 
any  way  and  therefore  maintains  its  high  viscosity  at  body 
temperature. 

Action  and  Remedial  Uses 

Liquid  Petrolatum  Squibb,  Heavy  (Californian),  is  not 
an  aperient,  a  laxative,  a  cathartic  or  a  purgative,  but  a 
mechanical  lubricant.  It  is  not  absorbed  by  the  stomach 
or  intestine,  does  not  act  on  and  is  not  acted  upon  by  the 
fluids  of  the  gastro-intestinal  tract, 
and  passes  out  of  the  body  un- 


EVACUANT 
FOR 
GENERAL  USE 


changed  and  in  the  same  quantity 
that  it  entered.  During  its  passage 
it  lubricates  the  lumen  of  the  gut, 
softens  faeces,  prevents  injury  of 
the  mucous  membrane  by  scybala, 
allows  repair  of  an  already  abraded  mucosa,  relieves  ir- 
ritated or  fatigued  myenteric  ganglia,  and  thus,  by  per- 
mitting a  rapid  passage  of  the  intestinal  contents,  prevents 
the  proliferation  of  bacteria  and  the  production  of  toxins 
and  a  consequent  toxaemia.  In  short,  its  use  establishes 
and  maintains  a  proper  body  drainage,  i.e.,  a  normal 
bowel  activity,  allowing  better  digestion  and  absorption  of 
food,  without  the  formation  of  a  habit. 

Liquid  Petrolatum  Squibb,  Heavy    (Californian),  is 
used  to  correct  the  constipation  of  pregnancy,  to  avoid  the 
hemorrhoidal    condition   which   so 
often  attends  it,  to  prevent  or  re- 


DURING  PREG- 
NANCY AND 
LACTATION 


lieve  postpartum  intestinal  stasis, 
and  for  all  other  conditions  for 
which  it  is  indicated.  Liquid 
Petrolatum  Squibb  may  be  used 


SQUIBB'S  MATERIA  MEDICA       499 


by  the  mother  in  any  necessary  amount,  without 
fear  of  any  influence  on  her  child,  since  the  oil  does 
not  enter  the  maternal  circulation,  but  exercises  its 
influence  in  a  mechanical  way  in  the  gastro-Jntestinal 
tract  alone. 

It  is  used  surgically  as  an  aid  in  differentiating  a  surgi- 
cal intestinal  case  from  one  non-surgical;  also  as  a  pro- 
phylactic to  prevent  the  ascent  of 
intestinal  bacteria,  thereby  pre- 
venting secondary  infection  of  bili- 
also  to  regulate  the  bowels  before 


IN  SURGERY 


ary  and  other  ducts; 
and  after  operation. 

It  is  useful  as  a  dressing  for  burns,   also   for  nasal 
packings  and  spray. 

Liquid    Petrolatum    Squibb,    Heavy     (Californian) , 
sprays    better    than    does    a    light 

IN  NOSE  oil,  and  lubricates  the  nasal 
AND  THROAT  mucosa  more  thoroughly  and  the 
lubrication  is  more  lasting.. 


As  pure  liquid  petrolatum  has  no  physiological  action, 
it  may  be  given  in  any  quan- 


ADMINISTRATION 
OF  SQUIBB'S 
MINERAL  OIL 


tities  without  harm.  As  it  is 
not  chemically  active  and 
resists  chemical  change,  it  is 
compatible  with  any  medica- 
cation  indicated.  However,  certain  facts  about  dosage  are 
worthy  of  note.  The  length  and  calibre  of  the  gastro- 
intestinal tract  differ  not  only  with  age,  but  in  different 
individuals  of  the  same  age,  therefore  the  quantity  of  oil 
necessary  for  lubrication  may  vary.  Also  the  conditional 
for  which  heavy  liquid  petrolatum  is  indicated  are  various, 
so  the  size  and  number  of  doses  will  vary.  Then,  too, 
there  must  be  considered  the  nature,  amount  and  consis- 
tency of  the  contents  of  the  bowel ;  the  pathological  relax- 
ation or  hypertonicity  of  the  intestinal  walls ;  the  degree  of 
entero-  or  viscero-ptosis ;  the  number,  kind  and  place  of 
adhesions,  bands  or  kinks;  also  whether  the  life  of  the 
patient  is  active  or  sedentary. 

Larger  and  more  frequent  doses  are  necessary  at  the 
beginning  of  treatment  than  after  a  normal  intestinal 
condition  has  been  established.  In  everp  case  a  mini- 


500       SQUIBB'S  MATERIA  MEDICA 

mum  regulating  dose  should  be  determined  and  main- 
tained, not  because  more  oil  would  do  harm,  but  because 
it  would  be  wasted. 

Intestinal  lubrication  can  be  produced  best  when  the 
gastro-intestinal  tract  is  comparatively  empty.  The  best 
time  for  administration,  then,  is  between  meals  and  at 
bedtime.  However,  individual  preferences  for  other 
times  may  be  gratified. 

For  an  adult,   to  begin  with  one  tablespoonful  twice 
a  day  between  meals  and  on  go- 
)OSAGE  or  je- 


creasing    the    same    according    to 
effect  desired.     Children  and  infants  in  proportion. 

As  Liquid  Petrolatum  Squibb,  Heavy  (Calif  ornian)  , 
is  odorless  and  tasteless,  flavoring  or  a  menstruum  is  not 
necessary,  although  such  may  be  added  if  desired. 

The  following  facts  concerning  Squibb's 
Mineral  Oil  are  worthy  of  emphasis: 

/.  Liquid  Petrolatum  Squibb,  Heavy  (Calif  ornian) 
is  a  pure  naphthene  oil.  This  is  an  important  fact  be- 
cause a  naphthene  oil  is  not  likely  to  be  contaminated 
with  hydrocarbons  which  can  be  absorbed  from  the  in- 
testine by  the  human  system,  while  all  other  American 
oils,  as  well  as  Russian  oils,  are  quite  likely  to  be  so 
contaminated. 

Explanation.  —  Paraffin  crudes,  i.e.,  petroleum  as  it 
comes  from  the  earth,  contain  many  hydrocarbons  be- 
sides those  which  belong  to  the  methane  series.  Such 
are  olefins  and  acetylenes,  and  other  unsaturated  hy- 
drocarbons. These  unsaturated  hydrocarbons  are 
readily  absorbed  by  the  human  system  and  cause  bodily 
harm  when  so  absorbed.  In  refining,  it  is  more  or  less 
difficult  to  free  a  paraffin  oil  from  all  olefins,  etc.,  if 
such  are  abundant  in  the  crude,  and  an  oil  is  undesir- 
able for  internal  use  if  it  contain  any  olefins  or  other 
unsaturated  hydrocarbons. 

Again,  olefins,  acetylenes,  and  similar  hydrocarbons 
may,  under  certain  conditions,  be  formed  from  pure 
paraffin  oil,  in  spite  of  the  greatest  care  to  avoid  the 


SQUIBB'S  MATERIA  MEDICA        501 

formation  of  them.  Thus,  when  crude  petroleum  is 
refined  in  an  endeavor  to  get  a  paraffin  oil  as  pure  as 
possible,  what  is  known  as  "cracking"  may  occur. 
"Cracking"  is  a  technical  term  which  denotes  a  change 
of  some  hydrocarbons  into  hydrocarbons  of  lower  density 
and  of  other  different  characterises.  This  is  due  to  the 
heat,  pressure,  etc. 

Sometimes  "cracking"  is  done  purposely  to  obtain 
these  different  hydrocarbons,  but  when  paraffin  is  refined 
the  heat  and  time  necessary  for  refining  may  cause  differ- 
ent hydrocarbons  to  form,  although  they  may  not  be 
desired.  It  is  therefore  difficult  to  obtain  a  pure  paraffin 
oil.  I 

Naphthenes,  however,  are  much  more  stable  than 
paraffins  and  resist  chemical  action  much  more  strongly. 
Again,  in  highly  concentrated  naphthene  crudes,  such  as 
those  from  California,  undesirable  hydrocarbons  or  other 
compounds  do  not  exist  in  any  quantity,  and  the  stability 
of  the  naphthene  molecule  allows  a  refining  process  which 
can  easily  free  the  oil  from  any  and  all  undesirable  com- 
pounds that  may  be  present,  and  this  without  the  forma- 
tion of  olefins  or  other  unsaturated  hydrocarbons.  I 
*  Therefore,  while  a  paraffin  oil  may  not  be  a  safe  or 
otherwise  desirable  oil  for  internal  use,  a  naphthene  oil 
(refined  from  Calif ornian  crude  composed  almost  en- 
tirely of  naphthenes)  is  faultless. 

Further,  and  what  also  is  important,  a  naphthene  oil  is 
capable  of  a  much  higher  viscosity  than  is  a  paraffin  oil. 

Such  a  pure,  safe,  and  highly  viscous  naphthene  oil 
is  Liquid  Petrolatum  Squibb,  Heavy  (Californian). 

II.  Liquid  Petrolatum  Squibb,  Heavy  (Calif ornian) , 
is  superior  not  only  to  all  other  American  mineral  oils, 
but  also  to  the  Russian  oils. 

Rxplanaiion. — For  two  reasons  a  naphthene  oil  is 
superior  for  internal  use  to  any  paraffin  oil. 

1.  Because  a  naphthene  oil  is  not  contaminated  with 
"unsaturated"  hydrocarbons.  Unsaturated  hydrocar- 
bons are  olefins,  acetylenes,  etc.,  which  because  some 
carbon  atoms  in  the  molecule  are  not  saturated  with 
hydrogen,  i.e.,  have  more  than  one  bond  of  union,  may 


502        SQUIBB'S  MATERIA  MEDICA  • 

be  absorbed  from  the  intestinal  tract  and  do  harm  when 
in  the  human  system. 

2.  Also,  a  naphthene  oil  can  be  made  to  have  a  much 
higher  viscosity,  and  the  chief  value  of  a  mineral  oil 
for  internal  use  depends  upon  its  high  viscosity. 

All  American  mineral  oils  except  Liquid  Petrolatum 
Squibb,  Heavy  (Californian)  are  composed  chiefly  of 
paraffins.  Liquid  Petrolatum  Squibb,  Heavy  (Cali- 
fornian), is  composed  wholly  of  naphthenes.  Further, 
a  Russian  mineral  oil  is  not  necessarily  a  naphthene  oil. 
It  is  true  that  the  Russian  Baku  oil  has  been  found  to 
contain  about  80%  of  naphthenes.  However,  other 
Russian  oils  (like  the  Pennsylvania  oils)  are  composed 
principally  of  paraffins.  Thus  a  mineral  oil,  although  it 
may  be  a  genuine  Russian  oil,  may  be  no  better  than  an 
ordinary  American  oil,  while  even  if  it  is  a  genuine  Baku 
oil,  the  best  that  Russia  has  to  offer,  it  is  not  as  good  as 
the  Californian  oil,  which  is  the  best  the  world  has,  be- 
cause even  in  the  crude  it  is  composed-  almost  entirely  of 
naphthenes. 

So  then,  if  the  best  Russian  mineral  oil  were  under 
consideration,  the  Heavy  Californian  Oil  is  superior  to  it, 
because  Heavy  Californian  Oil  is  composed  entirely  of 
naphthenes.  This  is  both  an  important  distinction  and 
an  important  difference. 

///.  A  highly  viscous  oil  will  lubricate  the  walls 
of  the  intestine  and  otherwise  act  in  the  bowels  better 
than  will  a  thin  oil.  A  naphthene  oil  has  a  much  higher 
true  viscosity  than  has  a  paraffin  oil.  Therefore  a 
pure  naphthene  oil  is  the  best  mineral  oil  for  internal 
use. 

Explanation. — Lubricating  the  intestine,  softening  the 
faeces,  and  inhibiting  bacterial  growth  and  the  speedy 
removal  of  faeces  from  the  colon  are  the  four  valu- 
able factors  in  the  successful  working  of  mineral  oil  for 
internal  use,  and  any  mineral  oil  offered  for  internal  use 
should  fulfil  all  these  requirements,  which  it  cannot  do 
unless  it  has  a  sufficiently  high  true  viscosity. 

The  more  viscous  the  oil  the  more  slowly  it  is  dis- 
tributed over  the  inside  walls  of  the  intestine;  the  more 


SQUIBB'S  MATERIA  MEDICA        503 

tenaciously  it  holds  to  the  bowel  wall,  and  the  longer 
its  lubrication  remains  effective.  (Thin  oils  quickly  run 
off  from  the  walls,  collect  in  the  rectum,  and  leak 
out). 

The  more  viscous  the  oil  the  more  intimately  it  will 
mix  with  the  faeces.  Also  a  thin  oil,  even  after  mixing, 
may  run  out  again.  The  more  viscous  the  oil  the  longer 
it  will  remain  mixed.  Indeed,  a  highly  viscous  oil  when 
once  mixed  with  the  fasces  will  not  separate  from  them 
before  the  faeces  are  expelled.  The  permanent  mixing 
effectually  softens  the  faeces,  keeps  them  soft,  and  favors 
speedy  and  easy  expulsion,  without  injury  to  the  bowel 
wall. 

Again,  the  more  thoroughly  a  mineral  oil  is  mixed  with 
the  faeces  the  less  water  (moisture)  the  faeces  can  contain. 
Moisture  is  necessary  for  the  growth  and  increase  in 
numbers  of  bacteria.  This  keeping  water  out  of  the 
faeces  is  one  way  in  which  a  viscous  mineral  oil  inhibits 
bacterial  growth. 

Another  way  in  which  the  growth  and  numerical  in- 
crease of  bacteria  is  prevented  by  a  highly  viscous  oil 
such  as  Squibb's  Mineral  Oil  is  by  coating  with  oil  the 
material  used  as  food  by  the  bacteria,  and  also  by  coat- 
ing the  bacteria  themselves. 

All  micro-organisms  require  food  if  they  are  to  grow 
and  multiply,  and  if  this  food  is  so  enclosed  in  a  coating 
of  oil  that  the  bacteria  can  not  get  at  it,  or  make  use 
oT  it  if  they  do  come  in  contact  with  it,  or  if  the  micro- 
organisms themselves  are  so  covered  that  they  cannot 
receive  nourishment,  they  cannot  grow  and  multiply.  A 
thin  oil  will  not  effectively  coat  either  food  of  use  to 
bacteria  or  the  bacteria  themselves,  while  a  highly  viscous 
oil  will  coat  both.  Thus  Liquid  Petrolatum  Squibb, 
because  it  is  highly  viscous  at  the  temperature  of  the 
inside  of  the  intestine,  effectually  deprives  intestinal  bac- 
teria of  the  nourishment  necessary  for  their  growth  and 
proliferation. 

Again,  a  highly  viscous  oil  effectively  coats  the  inside 
of  the  intestine  and  permits  the  healing  of  any  abrasions. 
It  is  quite  common  for  food  residues  to  wound  the  intes- 
tine. These  little  wounds  may  let  bacteria1  and  toxins 


504         SQUIBB'S  MATERIA  MEDICA 

enter  the  blodd  stream.  Thin  oils  neither  coat  the 
intestine  thoroughly  enough,  nor  for  a  sufficiently  long 
time  to  permit  healing.  A  highly  viscous  oil,  such 
as  Squibb's  Mineral  Oil,  will  effectively  coat  the 
abraded  surface  and  give  ample  opportunity  for 
healing. 

IV '. — A  normal  passage  of  the  bowel  contents  is  to  be 
sought  and  maintained  because  an  abnormal  delay  in  the 
passing  on  and  out  of  the  contents  of  the  intestine  causes 
many  conditions  which  produce  ultimate  discomfort  or 
disease. 

Explanation. — If  there  is  stasis,  i.e.,  a  slowing  of  the 
normal  movement  of  the  bowel,  then  irritation  of  the 
lining  membrane  of  the  intestine  and  even  inflammation 
of  it  may  result.  Delay  allows  the  proliferation  of 
bacteria.  Now  bacteria,  by  their  action  on  proteids, 
may  produce  substances  that  may  act  as  poisons 
(toxins)  if  they  are  absorbed  into  the  system  from  the 
bowel. 

Therefore  if  bacteria  increase  abnormally  there  may 
be  produced  toxins  which  a  diseased  intestinal  membrane 
may  absorb,  and  these  toxins  when  in  the  system  may 
cause  trouble  in  parts  of  the  body  remote  from  where 
they  entered.  A  thin  mineral  oil  cannot  keep  up  a 
normal  movement  of  the  bowel,  or  indeed  any  series  of 
continual  movements,  unless  it  is  taken  §o  frequently  and 
in  such  quantities  as  to  cause  distress,  indigestion  and 
leakage. 

As  Liquid  Petrolatum  Squibb,  Heavy  (Californian) , 
is  pure  and  highly  viscous,  it  will  produce  and  continue 
desirable  bowel  movements  and  finally  restore  normal 
bowel  activity,  and  will  do  this  without  forming  a  habit 
of  taking  oil. 

Further,  as  the  necessary  dosage  of  Squibb's  Mineral 
Oil  is  small,  it  is  an  economical  oil;  also  in  any  such 
dosage  there  will  be  no  leakage  or  other  disagreeable 
symptoms  attending  its  use. 

V ' . — //  desirable  results  from  the  use  of  a  good  min- 
eral oil  are  to  be  had,  attention  must  be  given  to  the 
natural  way  the  oil  worffs  as  well  as  to  the  natural 


SQUIBB'S  MATERIA  MEDICA        505 

the  bodily  organs  are  affected  by  oil,  i.e.,  the  size  of 
the  dose  and  the  time  of  taking  must  be  taken  into 
account.  This  is  as  true  of  mineral  oil  as  of  any  other 
remedy. 

Explanation. —  1.  Mineral  oil  in  the  stomach  may 
coat  over  large  masses  of  food.  Now,  as  it  is  neces- 
sary for  the  digestive  fluids  to  have  free  access  to  food 
if  a  normal  digestion  is  to  take  place,  and  as  the  digestive 
fluids  cannot  easily  get  at  masses  of  food  coated  with 
mineral  oil,  it  is  evident  that  mineral  oil  should  not 
be  taken  at  a  time  when  such  coating  of  food  could 
take  place,  namely  within  an  hour  before  or  after 
eating. 

Although  the  chances  of  noticeable  disturbance  from 
this  cause  may  be  remote  in  many  cases,  inasmuch  as  it  is 
never  necessary  to  take  mineral  oil  near  the  time  of 
eating,  it  is  best  to  avoid  taking  mineral  oil  wtihin  one 
hour  of  eating,  either  before  or  after. 

2.  Another  physiological   action  of  mineral  oil,   one 
with  which  you  need  not  burden  your  mind  but  which, 
in  order  to  meet  some  doctor's  difficulty,  you  may  find 
it  necessary  at  times  to  recall,  is  this:      As  long  as  oil 
of  any  fciW  is  in  the  stomach,  the  pylorus  does  not  open 
as  often  or  as  fully  as  it  does  if  no  oil  is  present,  and 
thus  food  is  kept  in  the  stomach  longer  than  it  should  be 
retained.      Such  a  delay  may  cause  symptoms  of  indi- 
gestion.     This  condition  can  be  prevented  by  avoiding 
the  taking  of  oil  near  the  time  of  eating. 

3.  If  much  more  oil  than  is  necessary  to  completely 
lubricate  the  walls  of  the  intestine  and  to  fully  soften  the 
faeces  is  taken,   the  excess  may   leak  out,   so   it  is  well 
not  to  take  excessive  doses  of  the  oil. 

VI. — Liquid  Petrolatum  may  dissolve  intestinal  tox- 
ins, hold  them  in  solution  and  quickly  eliminate  them 
from  the  body. 

Explanation. — Under  abnormal  conditions  in  the 
bowel,  various  products  may  be  formed  which  not  only 
may  cause  distress  in  the  intestine,  but  also,  if  they  are 
absorbed  in  the  system,  may  act  as  poisons  (toxins). 
These  when  held  in  solution  by  liquid  petrolatum  are 


506        SQUIBB'S  MATERIA  MEDICA 

not  as  likely  to  be  absorbed  in  the  system  as,  when  they 
are  free  and  they  will  be  eliminated  quickly  with  the 
stools.  Sometimes  these  substances  have  color  and  the 
liquid  petrolatum  holding  them  in  solution  may  be  seen 
colored.  However,  all  color  of  liquid  petrolatum  as  it 
appears  in  the  stools  is  not  due  to  toxins.  Many  non- 
toxic  substances  may  color  it. 

This  speedy  and  non-irritating  elimination  of  the  con- 
tents of  the  bowel  by  liquid  petrolatum  is  the  factor  of 
greatest  value  in  preventing  the  formation,  the  retention 
and  absorption  of  toxic  material. 

Vll. — As  Mineral  Oil  is  not  a  medicine  but  an  aid 
to  physiological  bodily  functioning,  it  may  be  necessary 
to  continue  the  taking  of  it  for  some  time  if  the  desired 
results  are  to  be  had. 

Explanation. — The  action  of  mineral  oil  when  taken 
internally  is  that  of  a  mechanical  lubricant  of  the  bowels, 
softener  of  the  faeces,  and  remover  of  toxins.  It  pro- 
tects the  membrane  and  prevents  injury  to  it,  while  it 
softens  faeces  and  prevents  the  accumulation  of  moisture 
in  them  and  hence  inhibits  the  growth  and  the  increase  of 
bacteria.  Thus  it  relieves  irritation,  allows  healing  of 
the  intestinal  membrane,  and  permits  normal  processes  of 
nourishing  the  body  to  be  restored.  In  other  words,  it 
puts  a  stop  to  abnormal  processes  and  allows  nature  to 
re-establish  normal  activities.  Nature  cannot  do  this  all 
at  once.  How  long  it  will  take  will  depend  on  how 
extensively  and  to  what  degree  the  normal  processes  have 
been  deranged.  The  oil  must  be  taken  for  a  time  long 
enough  to  permit  complete  restoration  of  the  normal 
bowel  activity.  It  is  of  interest  that,  however  long  the 
oil  may  be  taken,  no  habit  of  taking  oil  will  be  formed. 
So  the  taking  of  mineral  oil  should  be  persisted  in  until 
the  desired  results  are  had. 

VIII. — NOTE:  For  the  reasons  given  above,  and 
also  for  other  causes  which  it  is  not  possible  to  set  forth 
within  the  limits  of  such  brief  summaries  of  facts  as  have 
been  here  made,  it  is  important,  when  ordering  mineral 
oil  for  internal  use,  to  specify  SQUIBB'S. 


SQUIBB'S  CHLORINATED 

ANTISEPTICS  AND 

DISINFECTANTS 


Chloramine-T,  Chloramine-T  Paste; 

Dichloramine-T;  Chlorcosane; 

Halazone  Tablets. 


GENERAL 
DESCRIPTION 


Chloramine-T  Squibb  is  water-soluble,  while  Dichlor- 
amine-T Squibb  is  oil-soluble,  for  which  Chlorcosane 
Squibb  is  the  one  satisfactory 
solvent.  Chloramine-T  Sur- 
gical Paste  is  ready  for  imme- 
diate application.  These  are 
available  and  easily  used  antiseptics  and  are  of  the  high- 
est value  and  greatest  convenience  in  every-day  civil 
practice. 

Halazone  Squibb  is  an  effective  disinfectant  for  small 
quantities  of  water  for  drinking. 

It  should  be  borne  in  mind  that  while  the  result  of 
the  researches  of  Dr.  H.  D.  Dakin,  the  chloramines  are 
not  "Dakin's  Solution."  What 


CHLORAMINES 
ARE  NOT 
"DAKIN'S 
SOLUTION" 


is  technically  known  as  "Da- 
kin's  Solution"  is  a  neutral  solu- 
tion of  sodium  hypochlorite. 
It  is  an  efficacious  antiseptic  but 
requires  for  its  successful  use 
special  apparatus  and  a  twenty-four  hours'  service  of  a 
nurse,  inasmuch  as  a  continuous  application  is  necessary, 
as  well  as  frequent  bacterial  examination  of  the  wound. 
Then,  too,  the  solution  itself  is  difficult  to  make  and 
quite  unstable. 

The  chloramines  are  very  different  from  this.  They 
are  the  outcome  of  Dakin's  efforts  to  overcome  the  diffi- 
culties presented  by  the  neutral  solution  of  sodium  hypo- 
chlorite. So  while  the  Dakin  solution  is  efficacious  and 
of  value  in  military  hospitals  and  other  institutions  where 
specialists  in  chemistry  and  bacteriology  are  in  constant 
attendance  and  the  nursing  force  is  adequate,  the  chlor- 
507 


508       SQUIBB'S  MATERIA  MEDICA 

amines  are  of  value  in  small  hospitals  and  in  every-day 
civil  surgery  as  they  do  not  require  any  special  appa- 
ratus, specialists,  or  extra  personnel.  They  are  easily 
made  ready  for  use  by  simply  dissolving  the  Chlor- 
amine-T  in  water  or  the  Dichloramine-T  in  Chlorcosane. 
They  are  applied  by  means  of  gauze,  tampon,  packing, 
or  by  spray.  Renewal  oftener  than  once  in  twenty-four 
hours  is  seldom  necessary. 

CHLORAMINE-T  SQUIBB    (WATER-SOLUBLE) 

Chloramine-T,   a  name  shortened  for  convenience  in 

use    from    toluene-parasodiumsulphonchloramine,    desig- 

/~iji  /^DAIV/MVTI?  T        I      nates  a  white,  crystalline  solid, 
CHLORAMINE-T  .  ,  .  . 
j      without    odor,    and    containing 

12.6     percent,      of      chlorine. 

Readily  soluble  in  water,  its  solutions  have  a  bitter  taste 
and  are  comparatively  stable,  no  appreciable  decompo- 
sition taking  place  upon  exposure  to  ordinary  room  light 
and  temperature.  Compared"  w4th  an  equimolecular  solu- 
tion of  neutral  sodium  hypochlorite,  Chloramine-T 
gives  up  its  chlorine  less  rapidly,  has  an  antiseptic  value 
about  four  times  greater  than  that  of  the  hypochlorites, 
is  more  efficient  in  the  presence  of  blood  than  is  neutral 
sodium  hypochlorite,  has  a  relatively  slight  solvent  action 
on  necrotic  tissue,  has  a  prolonged  antiseptic  activity, 
and  is  less  irritating  than  the  hypochlorites.  "In  severe 
septic  conditions  much  of  the  Chloramine-T  is  promptly 
decomposed  by  the  secretions.  This  is  true  of  all  anti- 
septics of  the  chlorine  group  and  is  even  more  marked  in 
the  case  of  hypochlorites  than  with  Chloramine-T."1 

Dakin  writes,  "In  place  of  the  hypochlorite,  the  more 
stable  Chloramine-T   has  been   used   to   a   considerable 
extent  and  with  particular  suc- 
cess   in     fresh    industrial    acci- 


COMPARED  WITH 

SODIUM 

HYPOCHLORITES 


dents.  It  is  usually  used  in 
0.5-2  percent,  solution  and  its 
action  is  similar  to  that  of  hypo- 
chlorite save  that  necrotic  tissue 

is  less  rapidly  removed."2  Again,  "Chloramine-T  can  be 
used  in  stronger  solution  (up  to  two  percent.)  than  can 
the  hypochlorites.  It  is  more  stable  and  exerts  more  pro- 

*A  Handbook  of  Antiseptics,  by  Henry  Drysdale   Dakin   and  Edward 
Kellogg    Dunham. 


RELATIVE 
ACTION  OF 


SQUIBB'S  MATERIA  MEDICA        509 

longed  antiseptic  action.  ...  It  is  not  toxic  and 
is  less  irritating  than  the  hypochlorites."1  While  in  no 
case  inferior,  under  certain  conditions,  it  is  considerably 
more  efficient  than  are  they. 

Chloramine-T  may  be  used  in  solution  or  dry  (rubbed 
into  gauze)  or  in  a  paste*.  Dakin  says  that  Chloramine-T 
can  be  used  in  stronger  solu- 
tions than  can  the  hypochlo- 
rites. A  two  percent,  solution 
is  considerably  more  potent  than 
the  usual  solution  of  sodium  hypochlorite.  "It  is  not 
toxic  and  is  less  irritating  than  the  hypochlorites  and  has 
but  little  solvent  action  on  necrosed  tissue.  It  is  well 
suited  for  use  on  wounds  previously  cleansed  with  hypo- 
chlorites or  Dichloramine-T,  and  in  suitably  dilute  solu- 
tions may  be  used  in  the  eye  and  on  other  sensitive 
parts." 

"In  equimolecular  solutions  its  germicidal  activity  is 
about  four  times  that  of  sodium  hypochlorite,"  i.  e., 
Dakin's  Solution.2  .  .  .  "Its  germicidal  action  is 
rapidly  exerted  and  in  most  re- 


GERMICIDAL 
VALUE  OF 


STRENGTH  OF 
SOLUTION 


spects  it  resembles  the  hypo- 
chlorites closely,  though  de- 
cidedly less  irritating  than  the 
latter."3  It  may  be  applied  (for  wound  treatment)  in 
solution,  in  the  dry  state  as  an  impregnation  of  gauze,  or 
in  a  cream-like  paste.  .  .  .  "Although  there  were 
no  cases  reported  to  show  that  four  percent,  solutions  of 
Chloramine-T  were  unduly  ir- 
ritating, subsequent  experience 
has  shown  that  there  is  no  oc- 
casion for  exceeding  a  concen- 
tration of  2  percent.  For,  as  Chloramine-T  has,  weight 
for  weight,  as  great  a  germicidal  power  as  sodium  hypo- 
chlorite, a  2  percent,  solution  is  considerably  more  potent 
than  the  neutral  solution  of  sodium  hypochlorite  (Dakin's 
Solution),  usually  employed  (0.5  percent.).  The  2  per- 
cent, solution  may  be  used  for  the  treatment  of  septic 
wounds,  using  the  same  methods  as  employed  for  the 
hypochlorites."4 

1Dakin  and  Dunham,  Handbook  of  Antiseptics. 

2Ibid. 

"Ibid. 


FOR  CARRIERS 


510        SQUIBB'S  MATERIA  MEDICA 

Chloramine-T*  has  been  used  with  success  to  irrigate 
the    pleural    cavity    in    empyae- 

USES  OF  ma,    the    urinary    bladder,    the 

gall  bladder,  sinuses,  the  ure- 
thra, etc.  Also  as  a  douche  for  the  vagina,  the  ear  and  the 
nose.  It  has  also  been  found  to  e*ert  a  satisfactory  germi- 
cidal  action  in  the  eye  when  used  in  a  1:1  000  solution. 
'  To  disinfect  meningococcus  carriers  Chloramine-T 
used  by  steam  spray  and  applied  locally  in  water  solu- 
tions has  been  employed  with 
success.  Dakin  further  writes, 
"In  spite  of  limitations,  chiefly 
imposed  by  anatomical  conditions,  valuable  results  have 
been  obtained  .  .  .  with  the  use  of  antiseptics  in 
the  treatment  of  meningococcus  carriers  among  soldiers"1 
in  the  following  ways: 

1 .  By   use   of   steam    spray    and   solution    of    Chlor- 
amine-T. 

2.  Local  application  of  Chloramine-T  in  water  and 
especially  Dichloramine-T  dissolved  in  oil.     Gordon  and 
Flack  used  0.5  percent,  solution  of  Chloramine-T  or  1.2 
percent,   solution  of  zinc  sulphate.   "The  Chloramine-T 
gave  the  better  results  especially  with  persistent  carriers," 
although  to  a  slight  degree  it  was  not  as  well  tolerated  as 
the  solution  of   zinc   sulphate.      For   full   description   of 
methods  employed  and  the  character  of  results  the  original 
articles*   should  be   consulted.      Since  Chloramine-T   is 
non-toxic  and  is  stable,   "the  choice  of  strength  must  be 
left  to  the  judgment  of  the  surgeon.      In  practice,  it  is 

advisable  to  keep  a  2  percent, 
solution  in  stock  and  dilute  this, 

SOLUTION  OF  if  necessary,  either  with  water, 

or  in  case  of  considerable  dilu- 
tion, with  normal  saline  solution.  A  2  percent,  solution 
is  slightly  hypotonic  and  when  an  approximately  isotonic 
medium  is  desired,  normal  saline  solution  should  be  used 
as  a  diluent.  Chloramine-T, 
like  hypochlorites,  has  a  corro- 
sive action  on  most  metals  and 
should  not  be  used  for  the 


CORRODES 
METALS 


'Dakin  and  Dunham,  Handbook  of  Antiseptics. 

*For  authorities,  exact  references  to  quotations,  details  of  uses, 
etc.,  see  "Squibb's  Chlorinated  Antiseptics,  Disinfectants  and 
Solvents,"  Revised  Edition,  1918.  Qctober,  Brochure  No.  9. 


SQUIBB'S  MATERIA  MEDICA        511 

sterilization    of    instruments."1      For    sprays,    atomizing 
tubes  of  glass  are  preferable. 

Again:  "Chloramine-T  is  well  adapted  for  use  in  im- 
pregnated gauze,  for  which  very  few  substances  of  high 
.      antiseptic    value    have    proved 
DRY  IN  GAUZE  successful.      It  is  possible,   for 

example,   to   incorporate  in  the 

gauze  Chloramine-T  to  an  amount  equal  to  25  percent, 
of  the  weight  of  thg  gauze  .  .  .  an  amount,  how- 
ever, larger  than  is  advisable,  5  percent,  being  adequate. 
The  gauze  should  not  be  moistened  before 
use.  ...  It  can  be  used  dry  for  lightly  packing 
and  subsequently  moistened,  if  necessary,  when  in  posi- 
tion."2 Impregnated  gauze  is  of  most  value  in  recent 
wounds  to  check  progress  of  infection,  therefore  particu- 
larly useful  for  industrial  accidents  "where  treatment  can 
be  promptly  instituted." 

Further:  "Chloramine-T  and  Dichloramine-T  give 
materially  better  results  than  the  hypochlorites  when  act- 
ing on  organisms  in  a  blood  medium."3 

Chloramine-T  Surgical  Paste  Squibb  is  composed  of 
one  percent,  of  toluene-parasodiumsulphonchloramine  in 
the  neutral  base  sodium  stearate. 

This  paste  is  sufficiently  firm 
not  to  flow  away  when  applied 
to  a  wound  and  yet  fluid  enough 
to  be  moulded  to  the  anfractu- 


RATIONALE  OF 
CHLORAMINE-T 
SURGICAL  PASTE 


osities  of  a  granulating  surface 

or  of  a  fractured  bone. 

"Chloramine-T  Paste  is  designed  to  maintain  in  an 

aseptic  condition  wounds  which  already  have  been  dis- 
infected or  to  sterilize  wounds 


FOR  WHAT 
CHLORAMINE-T 
PASTE  IS  USEFUL 


which  are  only  slightly  infected. 
It  should  be  applied  only  to 
wounds  which  yield  small  quan- 
tities of  secretion;  which  have 
little  or  no  necrotic  tissue,  or  which  have  only  little  or 
no  infection."4  "Chloramine-T  Paste  cannot  sterilize 
severely  infected  wounds."5  Carrel  and  Hartmann, 

aDakin  and  Dunham,  Handbook  of  Antiseptics. 

-Ibid. 

3Ibid. 

Vottr.  E.\-p.  Med.,  N.  Y.,  XXVI,  p.  97. 

5Ibid.,  p.  118. 


512        SQUIBB'S  MATERIA  MEDICA 

after  prolonged  investigation,  state  as  their  conclusions 
that  "  ( 1 )  under  the  conditions  of  our  experiments  chlor- 
amine  paste  maintains  the  asepsis  of  a  wound  already 
sterile,  and  sterilizes  an  infected  wound.  (2)  Under  the 
same  conditions  chloramine  paste  causes  no  apparent 
modification  of  the  cicatrization  curve  of  an  aseptic 
wound."1 

Dakin  and  Dunham  write:  "When  the  frequent  re- 
newal of  the  antiseptic  is  impracticable  or  not  desired, 
recourse  may  be  had  to  pastes  or  oils  .  .  .  which 
embody  a  store  of  antiseptics  that  may  be  gradually 
utilized.  The  mild  antiseptic  action  ...  of  Chlor- 
amine-T  Paste  is  often  useful  to  maintain  sterility  and 
prevent  reinfection  of  wounds  which  have  previously 
received  more  vigorous  treatment."2  .  .  .  "The 
paste  is  not  oleagenous.  It  has  a  creamy  consistency 
and  can  be  spread  readily.  As  the  antiseptic  is  dissolved 
in  the  water  constituting  the  chief  bulk  of  the  paste,  it 
has  ready  access  to  the  parts  treated."3 

For  full  directions  for  the  use  of  Chloramine-T  Sur- 
gical Paste,  see  Journal  of  Experimental  Medicine,  Vol. 
XXVI,  pp.  91  and  9  7. 


DICHLORAMINE-T    SQUIBB     (OIL-SOLUBLE) 
(A)    Nature   of  Dichloramine-T 

Dichloramine-T,  shortened  for  convenience  in  use  from 
toluene  parasulphondichloramine,  is  the  name  of  a  crys- 
talline  solid,    slightly   yellowish 


DICHLORAMINE-T 
DEFINED 


in  color,  of  somewhat  sweetish 
taste,  and  having  a  pungent 
odor  resembling  chlorine.  It 

differs   from   Chloramine-T   in   having   the   sodium   atom 

replaced  by  an  atom  of  chlorine. 

Dichloramine-T  is  comparatively  stable  under  ordinary 

conditions  but  solutions  of  it  are  somewhat  unstable.      It 

is  only  very  slightly  soluble   in   water  but   rather   freely 


Voiir.  E.i'p.  Mcd.,  N.  Y.,  XXVI,  p.   118. 
-Dakin   and   Dunham,   Handbook  of  Antiseptics. 
3Ihid. 


SQUIBB'S  MATERIA  MEDICA        513 

soluble  in  chlorinated  eucalyp- 
SOLUBILITY  OF  [  tol,  and,  particularly,  in  chlor- 

-  cosane  (see  below).  It  is  a 
very  active  germicide.  Like  certain  other  compounds 
containing  chlorine,  it  should  be  protected  from  light 
and  be  kept  in  black  bottles. 

"Solutions  are  not  permanent,1  especially  in  the  pres- 
ence of  liquid  petrolatum,  but  a  1  0  per  cent,  solution  of 
Dichloramine-T  in  chlorinated  eucalyptol  may  be  kept  in 
a  colored  bottle  for  at  least  one  month  with  but  25  per 
cent,  decomposition."  This  solution  may  be  mixed 
extempore  with  chlorinated  paraffin  oil. 

Dakin  and  Dunham2  say  that  "when  prolonged  (anti- 

septic) action  is  required  and  frequent  application  is  im- 

possible,  recourse  must  be  had 

SURGICAL  to  more  stable  mixtures  which 

VALUE  OF 


yku  up  their  store  Of  antisep- 
tic    slowly,"    such    as    the    oily 

solution  of  Dichloramine-T. 

Again:   "Dichloramine-T  in  oil  solution  has  a  great 

advantage  over  the  other  chlorine  antiseptics  in   that  it 

may  be  used  in  high  concentration,  and  its  action  is  of 

much  longer  duration." 

(B)  Advantages  of  Dichloramine-T 

Lee,  Sweet,  Hendrix  and  Le  Conte3  write,  "We  offer 
as  a  solution  of  the  serious  obstacle  of  skin  irritation  of 
the  usual  chlorine  preparations  a  practically  stable,  non- 
irritating,  synthetic  double  chlor- 
amine  compound,  toluene-par- 
asulphondichloramine  or  Di- 
chloramine-T, this  chemical  to 
be  used  in  strengths  varying  from  5  to  1  0  per  cent,  (from 
twenty  to  forty  times  the  mass  of  germicide  ever  present 
in  the  usable  concentrations  of  hypochlorites)  dissolved  in 
a  chlorinated  oil  in  order  that  the  germicide  will  be  liber- 
ated over  a  period  of  from  eighteen  to  twenty-four  hours 
instead  of  from  thirty  minutes  to  one  hour,  as  with  the 
hypochlorite  solutions." 

lDakin,    Lee,    Sweet,    Hendrix,    Le    Conte,    Jour.    Am.    Med.    Assn., 

LXIX,  No.   1,   1917,  July  7,  p.   29,  col.   1. 
2Dakin    and    Dunham,   Handbook   of  Antiseptics. 
V.   A.  M.  A.,   1917,  July   7,   p.   29,   col.   1. 


NO  IRRITATION 
OF  SKIN  FROM 


514        SQUIBB'S  MATERIA  MEDICA 

(C)  HOTP  to  Use  Dichloramine-T 

Dakin  and  Dunham1  say,  "Dichloramine-T  dissolved 
in  oily  media  may  be  sprayed 
upon  wound-surfaces  or  poured 
into  accessible  parts  of  deep 

wounds.  ...  It  is  suitable  for  cases  requiring 
prolonged  antiseptic  treatment,  and  for  first  dressings  of 
recent  wounds  which  do  not  require  irrigation.  It  is  used 
also  for  nasal  antisepsis.  It  has  great  advantage  over 
other  chlorine  antiseptics  in  that 
ADVANTAGES  OF  it  may  be  used  in  high  concen- 

tration  and  its  action  is  of  much 

longer  duration.  Its  application  is  extremely  simple  and 
it  ordinarily  need  not  be  renewed  more  than  once  in 
twenty-four  hours." 

Dakin  and  Dunham  recommend  "for  surgical  purposes 
a  6.5  to  10  per  cent,  solution  in  treated  eucalyptol  and* 
paraffin   oil,       .       .       .       applied  by   a   glass   atomizer, 
poured   into  wound  cavities  or 


STRENGTH  OF 
OILY  SOLUTION 


introduced  into  sinuses  by  a 
cotton  swab.  The  amount  of 
the  solution  needed  for  each 
treatment  is  extremely  small,  1  to  2  Cc.  being  sufficient 
for  most  moderate  sized  wounds." 

"The  technic  of  the  application  of2  Dichloramime-T  is 

i      simplicity  itself  in  contradistinc- 

HOW  TO  USE  |      tion  to  lhal  O'f  Dakin>  Carrel, 

Dehelly  and  Depage.  After  a 

careful  surgical  preparation  of  the  wound  at  the  primary 
dressing,  and  excision  of  all  foci  of  infection  arid  of 
devitalized  tissues,  the  solution  is  applied  on  surface 
wounds  with  an  atomizer  in  the  form  of  a  spray.  In  deep 

wounds    the    cavities    are    filled 

with  the  liquid.  When  depen- 
dent  drainage  exists  because  of 

the  location  of  the  wounds,  or 

when  it  has  been  made  purposely,  the  lower  opening  is 
temporarily  closed  with  gauze  and  then  the  cavity  is  filled 
with  the  oil,  thus  covering  all  the  wound  surfaces.  The 

'Dakin  and  Dunham,  Handbook  of  Antiseptics. 

2Dakin,    Lee,    Sweet.    Hendrix   and    Le   Conte.,   J.   A.   M.   A.,   LXIX, 
No.    1,    1917,    July    7,    p.    29,    col.    2. 


SURFACE  AND 
DEEP  WOUNDS 


DEPENDENT 
DRAINAGE 


SQUIBB'S  MATERIA  MEDICA        515 

dependent  drainage  is  then  re-established  by  removing 
the  temporary  gauze  obstruc- 
tion. This  privilege  of  depen- 
dent drainage  cannot  be  prac- 
ticed with  the  use  of  aqueous 
solutions  and  the  Dakin-Carrel-Dehelly-Depage  technic 
in  which  the  wound  must  act  permanently  as  a  basin  to 
hold  the  weak  solution.  We  believe  that  too  much  stress 
cajmot  be  laid  on  this  advantage.  We  have  found  that 
it  is  necessary  to  apply  the  oil  but  once  in  twenty- 
four  hours,  and  the  wounds  should  be  covered  with  only 
a  few  layers  of  gauze  to  avoid  the  absorption  of  the  oil 
by  the  dressings." 


CHLORCOSANE  SQUIBB 
(THE  ONE  SOLVENT  FOR  DICHLORAMINE-T) 

Chlorcosane1      is      prepared 
from   paraffin   wax    by    replac- 
ing part  of  the  hydrogen  with 
chlorine.     It  is  a  bland,  almost 
tasteless  oil,  of  high  viscosity  and  in  itself  inert. 

Chlorcosane,  when  at  ordinary  room  temperature,  dis- 
solves Dichloramine-T  only  very  slowly.      "To  prepare 

solution  warm 


NATURE  OF 
CHLORCOSANE 


HOW  TO  DISSOLVE 
DICHLORAMINE-T 
IN  CHLORCOSANE 


about  one-quarter  of  the  amount 
of  Chlorcosane  required  to 
about  80°  Centigrade,  add  the 
Dichloramine-T,  stir  or  other- 
wise agitate  the  mixture  until  a  solution  is  had,  then  add 
the  remaining  three-quarters  of  the  Chlorcosane,  which 
should  be  at  room  temperature,  and  if  necessary  filter 
the  whole  solution  through  dry  fluted  filter  paper.  Chlor- 
cosane will  hold  from  8  to  1  0  per  cent,  of  Dichloramine 
when  the  solution  is  at  ordinary  room  temperature." 

"Solutions  of  Dichloramine-T  in  Chlorcosane  are  re- 
markably    stable     considering    the     high     reactivity     of 
Dichloramine.      Light     is     the 
greatest  cause  of  deterioration. 


STABILITY  OF 
SOLUTION 


Solutions    should     be     kept 
amber    (or,   preferably,   black) 

1The  substance  of  what  is  here  said  concerning  Chlorcosane  is  taken 
from  Major  E.  K.  Dunham's  Hertcr  Lectures,  New  York,  1918, 
January. 


HOW  TO  USE 
SOLUTIONS  OF 


516        SQUIBB'S  MATERIA  MEDICA 

bottles  and  protected  from  heat  and  moisture."  As  a 
rule  a  solution  properly  made  will  keep  under  favorable 
conditions  for  several  weeks.  Decomposition  should  be 
distinguished  from  the  formation  of  precipitate  on  account 
of  chilling  the  solution.  If  a  solution  of  Dichloramine-T 
in  Chlorcosane  is  chilled  to  a  certain  degree,  Dichlora- 
mine-T will  be  thrown  out  of  solution.  By  gently  warm- 
ing the  solution  this  precipitate  will  be  dissolved.  For 
application  to  wounds  a  solution  stronger  than  5  per  cent, 
of  Dichloramine-T  should  not  be  used. 

"The  solution  may  be  applied  directly  to  the  surface 
of  the  wound  by  any  convenient  way,  spraying  being 
considered  the  best."  Since  5  per  cent,  and  stronger 
solutions  are  too  viscous  for  use 
in  a  hand  atomizer,  a  power 
apparatus  is  necessary  with  a 
pressure  of  from  15  to  20 
pounds.  It  is  better  not  to  thin  the  solution  by  a  diluent. 
If  a  suitable  atomizer  is  not  available,  "a  grooved 
director,  cotton  swab,  medicine  dropper  or  a  glass  syringe 
may  be  employed.  ...  In  ordinary  wounds  the 
application  may  be  once  in  24  hours  and  the  dressings 
very  light.  For  gangrenous  or  for  foul  wounds  a  more 
frequent  application  should  be  made,  as  the  active  chlo- 
rine is  consumed  more  rapidly"  (by  such  wounds). 

For  spraying  the  naso-pharynx  a  1  per  cent,  or  a  2 
per  cent,  solution  is  best. 

HALAZONE  SQUIBB 

(FOR  THE  DISINFECTION  OF  SMALL  QUANTITIES 
OF  WATER) 

Dakin  calls  attention  to  the  unsuitableness  of  chlorine 
gas,  bleaching  powder  or  sodium  hypochlorite  for  the  dis- 
infection of  small  quantities  of  water.  Also  to  the  fact 
that  while  the  acid  sulphates  of  the  alkali  metals  are 
"undoubtedly  useful,"  the  taste  imparted  by  these  salts  is 
quite  disagreeable  to  some  persons,  the  solutions  of  them 
attack  metallic  water  bottles,  and  chiefly  they  do  not 
possess  the  potency  or  security  afforded  by  a  disinfectant 
of  the  chlorine  group.  Therefore  the  difficult  problem  of 
readily  sterilizing  small  individual  quantities  of  water  was 


SQUIBB'S  MATERIA  MEDICA        517 

carefully  studied  by  Dakin  because  of  its  importance.  As 
a  result  he  found  "the  most  suitable  substance  that  we 
have  as  yet  is  parasulphondichloraminobenzoic  acid." 

Halazone  is  a  short  term  for  parasulphondichloramino- 
benzoic acid,  Cl2N.SO2.C6H4.COOH.  It  is  a  white 
powder,  "sparingly  soluble  in  water  and  in  chloroform 
and  insoluble  in  petroleum."  It  is  best  kept  and  used  in 
tablet  form. 

Dakin's  experiments1  show  that  "a  concentration  of 
1  : 300000  will  sterilize  an  ordinarily  heavily  contami- 
nated water  (e.  g.  containing  coli,  typhoid  or  cholera 
organisms)  in  about  thirty  minutes."  It  has  little  or  no 
action  on  ordinary  metals, — a  "slight  action  . 
of  no  practical  moment  on  aluminum — and  imparts  'a 
just  perceptible'  but  not  disagreeable  taste  to  water.  Tea 
brewed  with  or  without  the  addition  of  Halazone  to  the 
water  cannot  be  distinguished.  Even  in  larger  doses 
Halazone  is  not  toxic." 

For  use  Halazone  should  be  combined  with  dry  sodium 
carbonate  or  with  dry  borax  as  such  increases  its  solu- 
I-IAT  A7ONF  bility  in  water.  Dakin  consid- 

T-ADI  tr-rc  ers  the   best   form   in  which  to 
lABLLlb  TJ  ,  ,, 
use    Halazone    is   tablets. 


"The  practical  success  of  the 

disinfectant  depends  very  largely  on  the  stability  of  the 
tablet."  If  properly  made  "tablets  are  quite  stable 
enough  for  practical  use.'  2 

Dakin  and  Dunham3  write,  "The  problem  of  steriliz- 
ing small  individual  quantities  of  water  .  is 
much  more  difficult  (than  of  large  quantities),  and  up 
to  the  present  it  has  not  been  perfectly  solved.  The  use 
of  hypochlorites  for  such  purposes  is  difficult,  owing  to 
the  instability  of  small  tablets  containing  the  minute  quan- 
tity of  active  disinfectant.  In  their  place  acid  sulphates 
of  the  alkali  metals  have  been  extensively  used  in  tablet 
form,  but  the  superior  potency  of  many  chlorine  com- 
pounds would  indicate  that  a  stable  potable  chlorine  dis- 
infectant suitable  for  the  sterilization  of  small  quantities 

^Handbook   of  Antiseptics,    Dakin   and   Dunham. 

2Ibid. 

•'British  Medical  Journal,   1917,   May  26,   I,  p.   682.      See  also   British 

Medical   Journal,    1916,    Jan.    29,    Proc.    Roy.    Soc.    B.    89,    1916, 

p.    232. 


518        SQUIBB'S  MATERIA  MEDICA 

of  water  is  desirable.  With  this  end  in  view,  we  have 
made  a  number  of  experiments  with  various  types  of 
substances,  one  of  which  we  believe  to  be  worth  practical 
application.  .  .  .  The  substance  which  is  the  most 
suitable  that  we  have  yet  found  is  parasulphondichlora- 
minobenzoic  acid  .  .  .  and  appears  to  be  effective 
and  reasonably  stable.  The  presence  of  the  COOH 
group  confers  a  slight  but  definite  degree  of  solubility  in 
water,  which  is  increased  by  dispensing  it  with  alkaline 
salts  such  as  sodium  carbonate  or  bicarbonate,  borax  or 
sodium  phosphate.  .  .  .  Since  the  synthetic  name  of 
the  disinfectant  is  inconveniently  long  for  ordinary  use, 
we  propose  to  apply  the  name  'Halazone'  to  the  tablets 
containing  it.  ...  From  the  results  (of  experi- 
ments) it  appears  that  a  concentration  of  1  : 300000  is 
sufficient  to  sterilize  an  ordinarily  heavily  contaminated 
water  in  about  thirty  minutes.  Such  a  concentration 
could  be  relied  upon  to  remove  colon,  typhoid,  or  cholera 
organisms.  Special  experiments  showed  that  the  sub- 
stance in  tablet  form  was  efficacious  when  acting  on  water 
contained  in  aluminum  bottles,  although  a  very  trifling 
action  on  the  metal  may  be  observed  if  tablets  are  allowed 
to  remain  undisturbed  in  long  contact  with  the  metal. 
We  believe  such  action  to  be  of  no  practical  moment. 
The  concentration  of  disinfectant  given  above  is  just 
perceptible  to  the  taste,  especially  in  warm  water  con- 
taining little  organic  matter,  but  the  water  is  perfectly 
palatable.  One  point  of  advantage  possessed  by  the 
present  disinfectant  over  most  hypochlorite  preparations 
is  the  fact  that  the  active  chlorine  is  less  rapidly  used  up 
so  that  the  process  of  disinfection  continues  for  a  con- 
siderably longer  period." 

The  various  Squibb  chlorinated  products  are  obtain- 
able in  convenient  packages,  as  follows: 

Chloramine-T  Squibb 
Powder — 

Amber  vial,  582  gr. 
Amber  bottle,  6^  oz. 

Surgical  Paste,  2  oz.  tube,  |/t  lb.,  1  lb.  bottles. 
Tablets,  4.6  gr.,  in  bottles  of  100,  500  and  1 ,000. 
Chlorcosane  Squibb,  |/4  pt->  1  pt-  bottles. 
Dichloramine-T  Squibb,  1  oz.,  '/}  lb.,  1  lb.  bottles. 


SUPERIORITY 
OF  SQUIBB'S 
TABLETS 


SQUIBB'S  MATERIA  MEDICA        519 
Squibb's  Tablets 

The  great  European  war  has  again  demonstrated  the 
value  of  tablet  medication.  Tablets  have  the  approval 
of  the  Medical  Department  of  the  U.  S.  Army  and 
Navy,  and  have  been  used  in  the  service  almost  to. the 
exclusion  of  pills  or  capsules. 

Squibb's  Tablets  differ  from 
all  others;  they  contain  the 
Squibb  quality  of  ingredients, 
the  formulas  are  more  scien- 
tifically studied,  they  are  ac- 
curate in  dosage,  and  because  of  rapid  disintegration, 
produce  prompt  and  definite  therapeutic  effects. 

The  rapidity  with  which  the  tablet  responds  in  the 
presence  of  watery  fluid,  such  as  the  saliva  or  gastric 
secretion  may  be  demonstrated  by  dropping  a  calomel 
or  bismuth  tablet  in  water  and  noticing  the  result.  Ad- 
vantage may  be  taken  of  this  fact  in  treating  children  or 
adults  who  cannot  swallow  a  tablet.  If  the  tablet  is 
put  into  a  spoon  and  a  little  water  added  the  tablet 
breaks  down  to  a  powdery  condition  at  once. 

The  coating  used  on  the  Squibb  Tablets  is  freely 
soluble,  and  applied  only  in 
sufficient  quantity  to  mask  the 
taste  during  the  process  of  swal- 
lowing; it  does  not  harden  by 
age,  and  only  momentarily  hin- 


COATED  TABLETS 
NOT  AFFECTED 
BY  AGE 


ders  the  disintegration  of  the  tablet,  at  the  same  time  it 
masks  all  disagreeable  odor  and  taste,  prevents  decompo- 
sition, and  retards  loss  of  volatile  ingredients. 

Examinations  in  our  Control  Laboratory  of  some 
chocolate-coated  Strychnine  Sulphate  Tablets  Squibb 
over  twelve  years  old,  demonstrated  the  coating  to  be 
freely  soluble,  the  disintegration  very  rapid  and  the  med- 
ical content  as  active  as  when  the  tablets  were  made. 

Squibb     Tablets     containing 
such   insoluble    medicaments    as 


TABLETS   OF 

INSOLUBLE 

MEDICAMENTS 


Acetanilid,  Aspirin,  Calomel, 
Bismuth  salts,  Salol,  etc.,  dis- 
integrate at  once  in  the  presence 


of  water,  in  the  saliva,  or  in  the  digestive  secretions. 


520        SQUIBB'S  MATERIA  MEDICA 
Squibb's  Superior  Botanicals 

All  the  botanical  and  other  crude  drugs  used  in  the 
Squibb  Laboratories  are  obtained  from  the  best  known 
sources  and  only  those  of  first 
quality  are  employed.  Ship- 
ments are  accepted  by  us  only 
after  they  have  been  examined 
and  passed  by  our  expert 


ONLY  FIRST 
QUALITY  DRUGS 
ACCEPTED 


pharmacognosists,  and  by  our  Control  Laboratories 
where  they  are  tested  chemically ;  and  in  many  instances 
they  are  subjected  to  additional  tests  in  our  Physiological 
Laboratories. 

Each  drug  is  first  examined  macroscopically  and 
microscopically,  to  establish  its  identity.  Then  it  is  thor- 
oughly garbled  to  remove  any  foreign  drugs  or  parts  of 
the  plant  which  may  have  been 
included  in  the  harvesting  and 


CAREFULLY 
EXAMINED   FOR 
FOREIGN  MATTER 


which  are  not  included  by  the 
official  definition.  For  example: 
If  the  bark  of  the  root  is  the 
part  which  the  Pharmacopoeia  directs  to  be  used,  we 
exclude  all  bark  of  the  stem  and  all  undue  quantities  of 
woody  material.  Likewise,  when  leaves  are  officially 
specified,  stems,  etc.,  must  not  be  present. 

Also  inspection  must  show  plainly  that  the  drug,  after 
collecting,  was  promptly  and  carefully  dried  and  kept 
in  a  clean  place ;  and  there  must  be  no  evidence  of  fer- 
mentation or  of  dirt  accumulated  during  the  drying.  Fer- 
mentation caused  by  packing  drugs  before  they  are  per- 
fectly dry  is  one  of  the  chief  causes  of  change  in  the 
active  principles. 

Drugs    for    which    the    Pharmacopoeia    prescribes    a 
definite  alkaloidal  strength,  are  assayed  carefully  to  make 
sure   they   are   at   least   of   that 
strength ;  and  in  those  instances 
where    biological    assay   is   offi- 

cially  suggested,  the  drugs  are 

subjected    to    the    proper    tests 

at  our  Physiological  Laboratories.  Furthermore,  we  also 
physiologically  test  and  standardize  our  ergot  prepara- 
tions, as  well  as  a  number  of  other  potent  drugs  for  which 
there  is  no  chemical  assay  established. 


ASSAYED 

CHEMICALLY  AND 
PHYSIOLOGICALLY 


SQUIBB'S  MATERIA  MEDICA        521 
Squibb's  Pure  Spices 

The  purity  of  spices  is  a  matter  of  as  great  importance 

as  is  the  quality  of  the  food  to  which  they  are  added. 

In   the  popular  mind   the   sole 

SPICES  ARE  value  of  spices  lies  in  their  prop- 

vJr     LMt,  1  EL  1  I\-  r     •  .•  11 

IMPORTANCE  erty  <Jl,  "npartag  an  agreeable 


flavor  to  food.  Aside,  however, 
from  this  well-known  virtue, 
spices  are  of  great  dietetic  importance,  and  their  selec- 
tion with  the  view  of  obtaining  them  of  full  strength  and 
of  a  high  standard  of  quality  is  deserving  of  careful 
consideration. 

However,  even  to-day  spices  are  adulterated,  or  low 
grades  and  exhausted  residues  are  reinforced  by  good 
ones,  to  be  offered  as  desirable  condiments. 

Appreciating   this   condition, 


A  LINE  OF 
PURE  SPICES 


the  House  of  E.  R.  Squibb  & 
Sons  supplies  a  line  of  spices 
which  are  absolutely  pure  and 
of  highest  quality.  These  can  unhesitatingly  be  recom- 
mended to  all  who  desire  condiments  of  distinctive  qual- 
ity and  such  as  are  free  from  sophistication  of  any  kind. 
The  whole  spices  are  selected  with  the  greatest  care, 
assayed  to  make  sure  they  come  up  to  the  high  standards 
set  by  the  Squibb  Laboratories,  and  then  immediately 
ground,  great  care  being  taken  to  avoid  volatilization  of 
the  essential  oils. 

Inasmuch  as  these  Squibb  Spices  are  pure  and  con- 
sequently of  exceptional  strength,  they  require  to  be  used 
in  quantities  much  smaller  than  ordinary.  Therefore, 
they  are  economical.  A  trial  is  convincing  of  their 
excellence. 

The  list  comprises:  Allspice,  Cinnamon,  Cloves,  Gin- 


THE  SQUIBB  LIST          ger'  ^ace,  Mustard  (English), 


OF  PURE  SPICES 


Nutmeg,  Paprika,  and  Pepper 
(black,  red  and  white).  These 
spices  are  put  up  in  air-tight, 
sifter-top  cans  holding  J/4  lb.,  2  ozs.,  and  1  oz.  respec- 
tively, convenient  for  table  use.  They  are  sold  only 
through  druggists;  they  are  not  obtainable  from  grocers. 


SPANISH  RYE 
ERGOT  BEST 


522        SQUIBB'S  MATERIA  MEDICA 

Squibb's  Ergot  Products 

The  House  of  E.  R.  Squibb  &  Sons  has  for  a  long 
time  been  recognized  as  the  first  producer  of  ergot  prep- 
arations of  exceptional  quality  and  absolute  reliability. 
What  Dr.  Stearns  was  to  the  introductory  therapy  of 
ergot,  Dr.  Squibb  has  b^|p  in  its  pharmacy;  he  studied 
it,  experimented  with  it  unceasingly,  and  established  the 
name  "Squibb's  Ergot"  firmly  in  medicine. 

Medicinal  ergot  is  a  poisonous,  parasitic  fungus  grow- 
ing on  rye.  Its  value  depends 
very  largely  upon  cautious  se- 
lection, thorough  cleansing, 
careful  preservation,  correct 
manipulation  until  all  its  essential  principles  are  ex- 
tracted, and  proper  packing  of  the  finished  product. 
Spanish  rye  ergot  is  far  superior  to  all  other  kinds,  as 
the  peculiar  atmospheric  conditions  of  the  Spanish  penin- 
sula favor  a  more  mature  and  otherwise  better  growth  of 
the  fungus.  Squibb's  Ergot  preparations  are  made  from 
this  Spanish  rye  ergot  exclusively.  Each  year  a  fresh 
lot  is  secured,  and  upon  receipt  of  an  importation  it  is 
subjected  to  a  very  thorough  process  of  cleansing  by 
which  all  extraneous  and  inert  matter  is  removed.  Then 
as  soon  as  practicable  this  clean  ergot  is  ground  and  im- 
mediately extracted  by  the  Squibb  repercolation  process, 
and  made  up  into  those  preparations  which  are  recog- 
nized as  safe  and  efficient  for  administration. 

Finally,  Squibb's  Ergot 


SQUIBB'S   ERGOT 
PRODUCTS  TESTED 
PHYSIOLOGICALLY 


preparations  are  carefully  tested 
physiologically  according  to  the 
method  recommended  by  Drs. 
Edmunds  and  Hale  (Hygienic 
Lab.  Bull.  No.  76),  and  admirably  conform  to  their 
standards.  Particular'  mention  may  be  made  of  Squibb's 
Sterile  Ergot,  an  alcohol-free  preparation  for  hypoder- 
mic or  intramuscular  injection,  physiologically  standard- 
ized so  that  each  mil  (Cc.)  represents  2  Gm.  of  Ergot. 
Consequently,  the  use  of  Squibb's  Ergot  in  any  of 
its  forms  is  in  no  sense  a  matter  of  clinical  experiment, 
so  often  attended  with  serious  risk,  but  the  application 
of  a  proven  remedial  agent  carefully  prepared,  tested 
and  standardized. 


SQUIBB'S  MATERIA  MEDICA       523 

Squibb's  Cascara  Products 

Cascara  Sagrada   (Rhamnus  Purshiana)  was  discovv 
ered  in   Montana,   on  the  banks  of  a  tributary  of  the 
Columbia  River,   about    1805, 


DISCOVERY    OF 
CASCARA  SAGRADA 


by  the  members  of  the  first 
North  American  transconti- 
nental exploring  expedition 
under  the  command  of  Lewis  and  Clark.  The  plant, 
along  with  a  number  of  other  unknown  drugs  collected  on 
the  journey,  was  sent  to  Frederick  Pursh,  a  German  bot- 
anist '  of  Philadelphia,  for  botanical  study ;  hence  the 
name  "Rhamnus  Purshiana." 

Fresh  Cascara  Sagrada  is  believed  to  contain  a  fer- 
ment which  is  said  to  be  responsible  for  unpleasant 
results  produced  when  the  drug  is  administered;  while 
it  is  maintained  that  the  seasoned  bark,  such  as  has  been 
kept  a  year  or  more  before 


WELL-SEASONED 
BARK  ONLY 
VALUABLE 


elaborating  it,  owes  its  valuable 
properties  as  a  laxative,  free 
from  griping,  to  the  fact  that 
the  ferment  has  been  exhausted 
by  standing.  The  Squibb  Laboratories  do  not  use  any 
cascara  bark  unless  it  has  been  seasoned  for  more  than 
a  pear;*  and  of  such  only  the  choicest  bark  is  employed. 
This  care  insures  a  maximum  of  efficacy  and  a  free- 
dom from  undesirable  by-effects  to  the  various  prepa- 
rations of  cascara  which  are  marketed  under  the  Squibb 
kbel-  These  include:  Extract, 


TA<;rARA 

L-AbCAKA  T--1    -j  A  .        i-i    -j 

PREPARATIONS  r  luidextract,    Aromatic    rluid- 

extract,  and  Fluid  Cascara 
Aromatic  Non-Alcoholic.  This 
non-alcoholic  product  is  identical  with  Aromatic  Fluid- 
extract  Cascara  U.  S.  P.  in  strength  and  flavor,  but 
the  alcohol  has  been  omitted  without  sacrificing  the  keep- 
ing qualities  of  the  preparation.  It  has  the  therapeutic 
advantage  of  eliminating  any  alcohol  effect,  a  result 
especially  desirable  in  the  case  of  children.  It  can 
unhesitatingly  be  recommended  in  preference  to  the 
official  preparations,  and  it  is  offered  at  a  lower  price 
because  of  the  absence  of  alcohol.  For  descriptions  of 
these  various  preparations,  see  the  respective  titles  in 
Part  I  of  this  book. 


524        SQUIBB'S  MATERIA  MEDICA 

Squibb's  Compound  Alum  Powder 

formerly  known  as  Surgical  Powder,  consists  of  ex- 
siccated alum,  camphor  and  carbolic  acid.  It  was  intro- 
duced by  Dr.  E.  R.  Squibb  in  1 868,  and  has  steadily 
grown  in  favor  among  the  medical  profession  as  an 
emergency  dressing  and  wash. 

As  a  styptic,  it  coagulates  blood  and  at  the  same  time 
contracts  ends  of  capillary  vessels,  thus  stopping  hem- 
orrhage unless  it  be  from  a  large  artery. 

As  an  antiseptic,  it  is  useful  as  a  first  dressing  for 
woundsy  to  which  it  may  be  applied  either  dry  or  in 
solution. 

As  a  stimulant,  it  hastens  formation  of  healthy  granu- 
lation tissue,  thereby  causing  rapid  healing  of  wounds. 

As  an  escharotic,  it  serves  to  destroy  exuberant  growth 
of  granulations  and  promote  normal  healing. 

As  an  absorbent,  it  keeps  the  wound  dry,  rendering 
foul  discharges  and  infection  from  outside  impossible. 

As  an  astringent,  it  prevents  hypersecretion  and  tends 
to  restore  the  mucous  glands  to  normal  activity. 

As  an  Emergency  Dressing,  Squibb's  Compound 
Alum  Powder  will  control  hemorrhage  and  prevent  sepsis, 
giving  time  to  prepare  necessary  material  or  transport 
the  patient  where  all  is  in  readiness. 

As  a  Routine  Dressing,  Squibb's  Compound  Alum 
Powder  serves  for  protecting  approximated  edges  of 
clean  wounds;  for  protecting  and  hastening  repair  in  all 
wounds  with  loss  of  tissue,  also  of  granulating  abdominal 
wounds  after  laparotomy;  for  cleaning  up  ulcers  of  any 
size  and  nature,  etc. ;  it  is  also  useful  in  solution  for  the 
nose  and  throat,  as  a  vaginal  douche,  etc.,  and  as  solu- 
tion or  powder  in  post-partum  hemorrhage. 

Squibb's  Compound  Alum  Powder  should  not  be 
sprinkled  on  sparingly,  but  applied  abundantly. 

Although  in  some  cases  its  application  may  cause 
slight  pain,  all  discomfort  soon  passes  away  and  the 
wound  remains  painless. 

Squibb's  Compound  Alum  Powder  is  offered  only  in 
sifter-top  cans,  which  should  be  kept  well  closed  and 
in  a  dry  place  when  not  in  use. 


SQUIBB'S  MATERIA  MEDICA        525 

Solution  Hypophysis  Squibb 

(SOLUTION  OF  PITUITARY  BODY) 

Solution  Hypophysis  Squibb  is  a  sterile  aqueous  solu- 
tion of  the  water-soluble  principles  of  the  posterior  lobe 
of  the  pituitary  body  (hypophysis  cerebri).  It  is  stand- 
ardized, a  1  :20,000  dilution  of  it  having  the  same  activ- 
ity on  the  isolated  uterus  of  the  virgin  guinea  pig  as  a 
1  :20,000,000  solution  of  histamine. 

Solution  'Hypophysis  Squibb  is  a  vaso-constrictor.   It 
is  also  a  powerful  stimulant  for 
unstriped     muscles,      especially 
those    of    the    uterus.       It    acts 
also  on  the  intestines  and  blad- 
der, particularly  when  there  is  lack  of  normal  tone.      It 
exercises   apparently   a   specific   action   on   renal   activity. 
It  has  been  employed  with  good  results  to  stimulate 
the  contractions  of  the  uterus  in 


PHYSIOLOGICAL 
ACTION  OF 


OF 

the   second   stage   of    labor,    in 

uterine  atony  and  post-partum 

hemorrhage,  as  well  as  in  certain  other  forms  of  uterine 
hemorrhage.  It  has  also  found  use  in  certain  forms  of 
pulmonary  hemorrhage.  In  post-operative  shock  and 
other  conditions  of  low  blood  pressure  its  use  has  been 
followed  by  favorable  and  persistent  results.  Its  stim- 
ulating action  on  the  intestines  and  bladder  have  made  it 
useful  m  the  retention  of  urine  and  the  intestinal  paresis 
and  distention  that  may  follow  abdominal  operations. 
In  diabetes  insipidus  its  administration  has  effectively  con- 
trolled the  thirst  and  polyuria. 

DOSAGE  ™e  d°s,e  ranff  from  °/3Lt0 

I.U  Cc.    (D  to   16  minims)   hy- 

podermically  or  intramuscular- 
ly, repeated  in  30  to  60  minutes  if  necessary.  The 
smaller  doses  are  used  when  it  is  desired  to  stimulate  the 
contractions  of  the  uterus  in  labor;  the  larger  to  control 
uterine  hemorrhage  or  relieve  shock  or  visceral  atony. 
The  skin  at  the  point  of  injection  should  be  sterilized, 
preferably  by  painting  with  tincture  of  iodine.  Solution 
of  Hypophysis  Squibb  is  put  up  in  1  Cc.  (1  mil=16 
min.)  and  0.5  Cc.  (0.5  mil=8  min.)  ampuls,  and 
offered  in  boxes  of  6  ampuls. 


526        SQUIBB'S  MATERIA  MEDICA 

Thromboplastin  Squibb 

Thromboplastin  Squibb  is  a  tissue  juice  from  ox  brain. 
It  contains  all  the  cerebral  thromboplastic  substances, 
including  a  full  complement  of  kephalin.  It  is  tested 
physiologically,  standardized,  and  then  kept  aseptic  by 
the  addition  of  0.3  per  cent,  of  tricresol. 
PURPOSES  Thromboplastin  Squibb  is  a 

trustworthy     hemostatic     ready 
for  instant  use.     It  is  efficacious 


MODE  OF 
ACTION 


in  all  kinds  of  capillary  hemorrhage.  It  will  not,  however, 
take  the  place  of  a  ligature  when  the  hemorrhage  is 
from  large  veins  or  arteries  or  from  arteries  of  moderate 
size.  It  should  not  be  relied  upon  when  the  vessels, 
however  small,  can  be  closed  by  clamp  ligature  or  torsion. 
Thromboplastin  Squibb  controls  hemorrhage  by  fur- 
nishing to  the  blood  principles  necessary  to  ensure  normal 
clotting.  It  does  not  act  me- 
chanically by  forming  a  local 
clot  nor  by  constricting  the  ves- 
sels but  by  a  true  physiological 
action. 

Thromboplastin  Squibb  is  supplied  in  two  forms,  i.  e., 
either  for  use  locally  or  for  use  hypodermically.  As  a 
rule  local  application,  which  should  always  be  free,  is 
effective.  If  it  does  not  prove  so,  then  Thromboplastin 
Hypodermic  Squibb  should  be  injected. 

Thromboplastin  Squibb  has  been  used  successfully  in 

WHEN  INDICATED         hemophilia;     hemorrhage    from 

the    umbilical    cord ;    from    the 

frenum  of  the  tongue;  from  the 

jaw  after  extraction  of  teeth;  for  bleeding  after  tonsi- 
lectomy  removal  of  adenoids,  etc.  By  oral  administration 
it  has  controlled  hemorrhage  from  the  stomach  also  in 
some  cases  from  the  intestine.  The  farther  from  the  pylorus 
the  site  of  hemorrhage  is  the  less  is  to  be  expected  from 
the  administration  of  Thromboplastin  Squibb  by  mouth 
as  it  is  likely  to  lose  some  of  its  activity  on  account  of 
digestion  during  its  passage  through  the  stomach,  duo- 
denum and  jejunum.  It  has  proved  efficacious  in  nasal 
hemorrhage  from  diphtheritic  and  other  toxic  conditions, 
in  hemorrhage  attending  acute  leukemia,  in  bleeding  from 
the  kidneys,  urinary  bladder,  prostate,  spinal  cord,  etc. 


SQUIBB'S  MATERIA  MEDICA       527 
Leucocyte  Extract  Squibb 

Leucocyte  Extract  Squibb  is  of  use  in  combating  in- 
i      factions,  and  is  a  product    the 

i  r        i  •   i     L         1_ 

value  or  which  has  been  ven- 
fied  by  biological  investigations 


and  established  by  clinical  experience. 

It   is  prepared   under  the   strictest   aseptic   conditions, 

r»nc-r>Ar>  ATM/™  according    to    the    method    of 

PREPARATION  i_r       D     •   •  -i 

Hiss,  by  injecting  a  sterile  veg- 

etable  protein   into   the   pleural 


cavities  of  rabbits  or  other  animals,  a  purulent  exudate 
is  incited,  which,  when  collected,  centrifuged,  purified, 
extracted,  and  proved  bacteria  free,  constitutes  Leucocyte 
Extract  Squibb. 

It  should  not  replace  specific  vaccines,  specific  serums 
INDICATIONS  or  specific  antitoxins.      It  is  of 

FOR  use  in  connection  with  the  indi- 

'      cated  vaccine  or  serum  in  acute 

constitutional  infections,  such  as  pyemia,  septicemia,  and 
sapremia.  Distinct  improvement  has  also  been  shown  to 
follow  its  use  in  labor  and  post-influenza  pneumonia. 
Equally  good  results  are  obtained  in  erysipelas.  It  may 
be  used  alone  while  an  autogenous  vaccine  is  in  prepara- 
tion or  may  be  used  by  itself  when  it  is  impossible  to 
obtain  a  satisfactory  diagnosis,  i.  e.,  impossible  to  deter- 
mine what  microorganism  causes  the  infection. 

In  such  cases,  as  a  rule,  Leucocyte  Extract  Squibb  is 
more  desirable  than  a  stock  vac- 
cine, and  its  use  is  always  more 


COMPARATIVE 
VALUE 


rational   than   that   of   a  mixed 
vaccine. 

Leucocyte  Extract  Squibb  is  put  up  in  syringes  of  1  0 
mils  (Cc.)  each,  which  is  the  average  dose  to  be  given 
one  to  three  times  daily.  After 
thorough  sterilization  at  the 
point  of  injection  the  extract  is 
injected  subcutaneously.  The  most  desirable  sites  for 
injection  are  the  abdominal  wall  and  the  loose  tissues  of 
the  back.  Complete  literature  will  be  sent  physicians 
on  request. 


528        SQUIBB'S  MATERIA  MEDICA 

Squibb's  Assayed  Tinctures 

The  physician  when  prescribing  an  alkaloidal  tincture, 
should  know,  and  has  a  right  to  demand,  that  a  product 
be  dispensed  from  which  he  may  obtain  prompt  action 
and  definite  results.  The  Squibb  Assayed  Tinctures  are 
made  from  the  best  selected  drugs,  in  strict  accordance 
with  the  official  formulas  and  processes,  and  are  carefully 
assayed  and  accurately  standardized.  In  the  case  of 
the  potent  tinctures  for  which  the  Pharmacopoeia  demands 
or  merely  recommends  physiological  assays,  those  prep- 
arations are  tested  by  the  methods  therein  outlined  and 
proved  to  be  of  standard  activity.  Uniformity  of  strength 
may  therefore  be  depended  upon.  The  following  list 
comprises  the  tinctures  to  which  assay  processes  are 
applied  according  to  the  latest  revision  of  the  U.  S.  P. 
A  comprehensive  description  of  each,  giving  its  prop- 
erties, uses  and  doses,  is  given  under  the  respective  titles 
of  these  tinctures  in  Part  I  of  this  book.  We  here 
append  a  list  of  them: 

Tincture  Aconite   Root  Squibb    (Tinctura  Aconiti). 

Tincture  Belladonna  Leaves  Squibb  (Tinctura  Bel- 
ladonna Folium). 

Tincture  Cannabis  Squibb    (Tinctura  Cannabis). 

Tincture  Cinchona  Squibb   (Tinctura  Cinchona). 

Tincture  Cinchona  Compound  Squibb  (Tinctura  Cin- 
chona Composita). 

Tincture  Colchicum  Seed  Squibb  (Tinctura  Colchici 
Seminis) . 

Tincture  Digitalis  Squibb   (Tinctura  Digitalis). 

Tincture    Digitalis    Fat-free    Squibb. 

Tincture  Hydrastis  Squibb  (Tinctura  Hydraslis). 

Tincture  Hyoscyamus  Squibb  (  Tinctura  Hyoscyami) . 

Tincture  Nux  Vomica  Squibb  (Tinctura  Nucis 
V  om\c&) . 

Tincture  Opium  Squibb   ( Tinctura  Opii) . 

Tincture  Opium  Deodorized  Squibb  (Tinctura  Opii 
Deodorati) . 

Tincture  Physostigma  Squibb  (Tinctura  Ph\isosiig- 
matis) . 

Tincture  Stramonium  Leaves  Squibb  (Tinctura 
Stramonii) . 

Tincture  Strophanthus  Squibb  (Tinctura  Strophanthi) . 


SQUIBB'S  MATERIA  MEDICA        529 

Physiological  Standardization 

Physiological  standardization  is  the  application  of 
quantitative  physiological  methods  to  medicinal  products 
in  order  that  they  may  be  uniform  in  potency.  The  idea 
of  such  standardization  is  not  new,  nor  are  the  methods 
employed  new,  but  are  such  as  have  been  in  constant  use 
for  some  of  the  finer  work  of  physiology  and  pharmacol- 
ogy. 

One  great  value  of  physiological  standardization  is  the 
determination  of  the  potency  of  certain  drugs  of  therapeu- 
tic importance  which  do  not,  however,  lend  themselves 
to  assay  by  chemical  or  by  physical  methods.  This  may 
be  because  the  active  principle  is  unknown  or  because 
the  chemical  reactions  or  the  physical  properties  revealed 
are  not  sufficiently  distinctive  to  be  of  value.  Further, 
the  active  principle,  although  known,  may  be  present  in 
such  a  very  minute  amount  that  assay  by  chemical  or 
physical  methods  can  not  be  accurate.  Also,  in  drugs 
in  which  there  are  several  active  principles,  chemical  and 
physical  analyses  may  for  many  reasons  be  impractical. 
If,  therefore,  such  drugs  can  be  standardized  physiolog- 
ically, that  is  to  say,  be  made  in  such  a  way  that  a  cer- 
tain bulk  of  them  will  always  produce  a  certain  physiolog- 
ical effect,  a  condition  most  valuable  for  clinical  medi- 
cine has  been  established. 

The  United  States  Pharmacopoeia,  IXth  Revision, 
has  provided  physiological  assay  for  certain  drugs.  All 
these  drugs  are  assayed  by  the  Squibb  Laboratories  ac- 
cording to  the  U.  S.  P.  method,  the  details  of  which  can 
be  learned  from  the  Pharmacopoeia.  Furthermore,  this 
standardization  has  been  extended  to  other  drugs  by  the 
Squibb  Laboratories  and  additions  to  the  list  will  be 
made  as  rapidly  as  processes  can  be  devised  for  such 
standardization. 

Thus  the  Squibb  Laboratories  constitute  one  of  the 
effective  means  by  which  knowledge  of  drugs,  the  science 
of  pharmacology,  is  advancing  and  by  its  contributions 
lo  general  knowledge  assume  a  share  in  the  establishment 
of  medicine  as  an  exact  science.  Brochures  on  the  sub- 
ject of  physiological  standardization  may  be  had  by 
physicians  upon  application. 


530        SQUIBB'S  MATERIA  MEDICA 

Sodium  Phosphate  Squibb 

Sodium  phosphate  is  now  prescribed  extensively  by 
the  medical  profession  and  is  also  used  by  the  laity  as  a 
laxative  and  mild  purgative.  It  is  also  said  to  regulate 
the  secretion  of  bile  and  is,  therefore,  a  very  important 
article. 

Much  of  the  sodium  phosphate  of  the  market  contains 
arsenic.  This  poisonous  impurity  is  due  to  the  sulphuric 
acid  used  in  the  process  of  manufacture.  Medical 
literature  describes  numerous  instances  of  serious  arsen- 
ical poisoning  which  it  attributes  to  the  use  of 
sodium  phosphate  containing  this  impurity.  In  many 
cases,  although  the  quantity  of  arsenic*  was  comparatively 
small,  the  accumulation  of  arsenic  in  the  system  from 
repeated  doses  of  the  sodium  phosphate  produced  dis- 
tressing and  in  several  cases  disastrous  results. 

Believing,  therefore,  that  the  physician-  should  have  at 
hand  and  that  there  should  be  available  for  the  public  a 
sodium  phosphate  that  is  free  from  arsenic,  the  Squibb 
Laboratories  furnish  a  product  that  fully  meets  such  a 
demand. 

All  of  Squibb's  sodium  phosphate  is  tested  for  arsenic 
by  a  method  that  is  far  more  delicate  than  that  suggested 
by  the  U.  S.  P.,  IXth  Revision,  and  in  all  analyses 
large  quantities  of  the  sodium  phosphate  are  used  in 
order  to  be  sure  that  Sodium  Phosphate  Squibb  can  be 
considered  arsenic-free  even  when  used  in  very  large  or  in 
often  repeated  doses.  Furthermore,  because  of  the 
process  of  recrystallization  which  it  has  undergone, 
Squibb's  Sodium  Phosphate  is  free  from  all  other  objec- 
tionable impurities.  It  is  colorless,  odorless,  and  has  a 
cooling,  saline  taste.  The  finished  product  is  granulated 
to  permit  of  more  convenient  dispensing  and  dosing  than 
is  obtainable  with  the  ordinary  crystalline  variety. 

It  enjoys  appreciative  use  among  those  who  realize  that 
quality  in  medicine  is  the  first  consideration.  Because 
sodium  phosphate  is  normally  a  very  efflorescent  chemical 
the  Squibb  product  is  placed  on  the  market  only  in  1  Ib. 
and  '/4  Ib.  sealed  tin  containers  and  not  in  the  cheap 
paste-board  cartons  in  which  so  great  a  part  of  the 
sodium  phosphate  of  commerce  is  found. 


SQUIBB'S  MATERIA  MEDICA        531 

Squibb's  New   Silver  Preparations: 
Solargentum  and  Protargentum 

Solargentum  Squibb  (sol=colloid,  a-rgentum=sil- 
ver)  is  a  true  colloid  of  metallic  silver;  and  Protar- 
gentum Squibb  (prot=protein,  argentum=silver)  is  a 

^^  true  colloid  of  a  salt  of  silver. 

NATURE   OF  c-     u  •     r  n    L 

iiach  possesses  in  rull  the  prop- 
erties of  its  respective  class.    See 

"Silver  Preparations,  Colloidal"  and  "Silver  Protein 
Compounds"  in  New  and  Nonofficial  Remedies,  1919. 
These  Squibb  silver  preparations  are  of  use  whenever 
colloidal  silver  or  silver  protein  is  indicated:  for  instance, 
INDICATIONS  FOR  for  P^phylaxis  or  for  the  treat- 
ment  or  gonorrhea  and  other  in- 
fections of  the  urethra ;  for  con- 


junctivitis and  other  infections  of  the  eye,  including 
ophthalmia  neonatorum ;  and  for  infections  of  the  ear, 
nose,  throat,  etc. 

Both  Solargentum  Squibb  and  Protargentum  Squibb 
are  freely  soluble  in  either  cool  or  warm  water.  For 

-  SOLUTIONS  OF  making  ,  "wj*™."     &^d 

water    should    be    used.        1  he 

temperature  of  the  water  pref- 
erably should  be  low,  and  even  for  use  cool  "solutions" 
are  more  efficacious  than  warm.  They  should  never 
exceed  37°  C  (98.6°  F).  When  made  properly,  "solu- 
tions" of  Solargentum  Squibb  are  stable.  "Solutions"  of 
Protargentum  Squibb,  however,  are  not  stable  and  there- 
fore they  should  be  made  only  as  wanted.  A  prescrip- 
tion for  Protargentum  Squibb  should  call  for  a  "fresh 
solution"  and  for  only  enough  to  last  the  patient  three 
days  or  less. 

In  making  aqueous  "solutions"  of  Solargentum  Squibb, 
the  entire  quantity  of  the  flakes  may  be  put  into  the  re- 
quired amount  of  water  and  the  whole  stirred  or  shaken. 
For  a  "solution"  of  Solargentum  Squibb  in  glycerin, 
first  moisten  the  required  quantity  of  flakes  with  a  few 
drops  of  cool  water  (only  enough  to  moisten  them  and 
make  them  into  a  very  thick  paste),  then  add  the 
glycerin  (cold),  in  which  the  pasty  Solargentum  Squibb 
will  dissolve  quickly.  Colloidal  silver  is  insoluble  in 


532        SQUIBB'S  MATERIA  MEDICA 

glycerin  alone.  Caution.  It  has  been  recommended  to 
heat  the  glycerin  in  a  mortar  and  grind  up  the  colloidal 
flakes  while  heating.  Such  a  procedure  almost  invariably 
will  destroy  the  colloid  and  render  the  "solution"  irri- 
tating and  less  active  as  an  antiseptic.  As  this  heating 
process  is  often  used  by  pharmacists,  care  should  be  taken 
that  only  the  "cold  water-glycerin"  process  be  used. 

To  make  a  "solution"  of  Protargentum  Squibb  it  is 
best  to  sprinkle  the  required  amount  of  the  powder  upon 
the  surface  of  the  water  and  allow  the  Protargentum 
Squibb  to  dissolve  itself  gradually,  which  it  does  in  a 
very  short  time.  If  simple  stirring  is  attempted,  the  wet 
powder,  will  mass  itself  on  the  stirring  rod  and  time  and 
patience  will  be  lost.  If  preferred  the  Protargentum 
Squibb  may  be  triturated  with  water  in  a  mortar. 

Solargentum  Squibb  contains  from  1  9  per  cent,  to  22 
per  cent,  pure  silver,  and  is  an  antiseptic  and  an  effective 
germicide.  When  mixed  with  water  it  will  not  ionize, 
PROPERTIES  OF  therefore  it  will  not  precipitate 

or  coagulate  protein.  Conse- 
quently in  any  strength  "solu- 
tions" it  is  non-caustic,  non- 
astringent,  non-irritating.  The  usual  strengths  of  "solu- 
tions" of  Solargentum  Squibb  for  clinical  use  are  from 
1  per  cent,  to  25  per  cent.,  or  even  50  per  cent. 

Protargentum  Squibb  contains  about  8  per  cent,  of 
pure  silver.  Upon  mixing  with  water  the  disperse  phase 
ionizes  while  in  colloidal  suspension.  Its  "solutions," 
therefore,  are  not  permanent,  are  slightly  irritating  and 
somewhat  astringent.  The  usual  strength  of  "solutions" 
of  Protargentum  Squibb  for  clinical  uses  are  from  '/4 
per  cent,  to  5  per  cent.,  an  average  strength  of  2  per 
cent,  being  ordinarily  preferred. 

It  should  be  borne  in  mind  that  a  colloid  of  metallic 
silver  always  can  be  used  in  a  "solution"  of  much  greater 
strength  than  can  a  silver  pro- 


SOLUT1ONS' 


IMPORTANT 
NOTE 


tein,  notwithstanding  that  the 
actual  silver  content  of  the  col- 
loid is  -much  greater  than  that 
of  the  protein.  Further,  for  equal  antiseptic  and  germ- 
icidal  action,  greater  strength  of  the  metallic  colloid  is 


SQUIBB'S  MATERIA  MEDICA        533 

necessary.  For  instance,  although  Solargentum  Squibb 
contains  about  20  per  cent,  of  silver,  two-and-a-half 
times  as  much  as  Protargentum  Squibb  contains,  the 
strength  of  clinical  "solutions"  of  Solargentum  Squibb  are 
from  1  per  cent,  to  50  per  cent,  as  against  an  average 
strength  of  2  per  cent,  for  Protargentum  Squibb. 

RV  i  T   d   M  The     United     States     Navy 

t>  I    U.  o.  IN. 


AND  U.  S.  A. 


11  1      .  i 

has  been  and  is  purchasing 
Solargentum  Squibb  in  very 
large  quantities  for  general 

distribution  to  their  medical  stations,  both  on  land  and 

sea,  at  home  and  abroad. 

Also  the  Medical  Department  of  the  United  States 
Army  has  been  and  is  using  Solargentum  Squibb  in 
rapidly  increasing  quantities.  Further,  it  has  adopted 
Protargentum  Squibb  for  the  prophylactic  treatment  of 
venereal  diseases,  the  strength  of  "solution"  authorized 
being  2  per  cent. 


Squibb's  Fluidextracts 

These  are  manufactured  from  the  most  active  drugs 
obtainable  on  the  market  or  possible  to  procure  by  direct 
importation.  Thorough  exhausting  of  the  assayed  and 
otherwise  tested  drug  assures  the  production  of  fluid- 
extracts  of  a  standard  strength.  These  all  contain  the 
maximum  amount  of  active  principle  and  accurately  repre- 
sent the  drug.  The  process  of  extraction  employed  is 
the  well-known  repercolation  process,  which  originated 
in  the  Squibb  Laboratories.  The  menstrua  are  those 
which  most  effectively  extract  the  medicinal  ingredients 
of  the  drugs,  and  thus  are  theoretically  true  solvents  of 
them;  and  the  strength  of  the  alcohol  employed  is  fully 
that  prescribed  by  the  U.  S.  P.  In  all  instances  in  which 
the  U.  S.  Pharmacopoeia  prescribes  a  definite  alka- 
loidal  strength  for  the  assayed  fluidextracts,  the  Squibb 
products  are  accurately  adjusted  to  that  standard;  and 
where  the  Pharmacopoeia  requires  or  merely  recom- 
mends a  p/7psio/ogfca/  assay  process  the  Squibb  fluid- 
extracts  are  carefully  tested  and  standardized  thereby. 


DEVELOPMENT 


534        SQUIBB'S  MATERIA  MEDICA 

Squibb's  Biological  Products 

The  production  of  antitoxic  serums,  bacterial  vaccines 
and  similar  biological  products,  for  the  immunization  and 
RAPID  specific  treatment  of  certain 

highly  infectious  diseases,  has 
made  rapid  development  dur- 
ing the  past  two  decades.  Ac- 
tive immunization  with  bacteria,  or  their  products,  has 
come  into  general  use,  not  only  as  a  preventive  measure, 
but  as  a  cure  of  infectious  diseases.  To-day  the 
rationale  of  vaccine  and  serum  therapy  has  become  so 
firmly  established  that  a  large  number  of  biological 
products  find  a  place  in  the  armamentarium  of  the  pro- 
gressive physician. 

The  Squibb  Biological  prod- 


THE  SQUIBB 
BIOLOGICAL 
LABORATORIES 


ucts  are  scientifically  prepared 
in  the  new  Squibb  Research 
and  Biological  Laboratories  at 
New  Brunswick,  N.  J.  These 
are  elaborately  equipped  with  the  most  up-to-date  ap- 
paratus, and  the  scientific  appointments,  under  the  direct 
supervision  of  Dr.  JOHN  H.  ANDERSON,  formerly 
Director  of  the  Hygienic  Laboratory,  U.  S.  Public 
Health  Service,  are  second  to  none  in  the  country. 

The  Squibb  Vaccines  are  prepared  under  the  most  im- 
proved scientific  methods.  The  stock  vaccine  is  a  prod- 
uct of  many  strains  of  each  organism.  Vaccines  are  of 
the  greatest  value  in  localized  infections.  Their  action  ex- 
tends to  cells  remote  from  the  seat  of  infection,  stimu- 
lating them,  too,  to  generate  antibodies,  which  the  blood 
current  brings  to  the  area  of  infection. 

The  Squibb  Serums  are  of 


THE  SQUIBB 
SERUMS 


high  concentration,  small  in 
ANH  v Arr IMF*  bulk'  and  high  in  P°tency  and 

AINU    VALClINtLD  rf    •  ji  i- j 

erhciency    and    low    in    solids. 

They  are  all  tested  with  the 
most  meticulous  care  by  biologic  laboratory  experts.  The 
clinical  effect  of  each  physiologically  tried  out  on  the 
specific  disease  for  which  it  is  prepared  as  a  curative 
agent.  The  Squibb  Vaccines  are  marketed  in  aseptic 
ampuls,  accompanied  by  a  syringe  for  each  package. 
The  antitoxins  and  serums,  with  the  exception  of  the 


SQUIBB'S  MATERIA  MEDICA        535 

anti-meningitic  serum,  are  distributed  in  special  aseptic 
syringes. 

The  Anti-Meningitic  Serum 


ANTI-MENINGITIC 
SERUM  SQUIBB 
IN  GRAVITY 
APPARATUS 


is  prepared  for  administration 
in  a  special  gravity  apparatus, 
which  has  the  advantage  of 

supplying  the  serum  in  a  sterile 

container  always  ready  for  use 

by  the  gravity  method  which  lessens  the  danger  to  shock. 
Specify  "SQUIB BS"  when  ordering  biological  prod- 
ucts, and  thus  insure  results. 


Food  Allergens  Squibb 

Allergy   is  hypersensitiveness  of   the  system  to  some 

material  introduced  into  it.  Al- 
DEFINITION  r     j  e     j 

lergy  to  roods,  or  rood  poison- 
ing, or  food  idiosyncrasy,  as  it 


MANIFESTATION 


is  sometimes  called,  is  a  hypersensitiveness  to  the  proteins 
which  enters  into  the  ordinary  diet  of  the  individual.  It  is 
due,  probably,  to  a  previous  sensitization  of  the  individual 
by  certain  proteins,  and  thus  is  a  form  of  anaphylaxis. 

Food   allergy   may  manifest 
itself   in   a   great   many   ways, 

~ e.g.,     by     the     appearance     of 

eczema,  asthma,  urticaria,  complicated  vasomotor  dis- 
turbances of  the  larger  air  passages,  cardio-vascular  con- 
ditions involving  the  kidneys,  and  in  many  other  ways. 

It  has  been  known  for  some  time  that  egg  white,  shell- 
fish, pork,  cow's  milk,  woman's  milk,  strawberries,  barley, 
oatmeal,  and  a  large  number  of  other  food  substances 
cause,  in  some  persons,  a  disturbance  sufficiently  marked 
to  demand  remedial  attention. 

In  the  treatment  of  food  allergy  the  first  important  step 

rMA^M^cic  is   to   determine   what   food   or 

DIAGNOSIS  r     j  ..L  •      j- 

roods    cause    the    systemic    dis- 

turbance.      This   can   be   done 

by  inoculating  the  patient  with  several  possible  food 
allergens  and  the  specific  food  protein  will  manifest  itself 
by  a  reaction  at  the  site  of  inoculation  as  described 
below.  Of  course,  the  food  protein  used  for  diagnosis 
must  be  pure. 


536        SQUIBB'S  MATERIA  MEDICA 

To  make  the  inoculation  it  is  necessary  only  to  wash 
the  inner  surface  of  the  fore- 
arm with  sterile  water  or  physi- 
ological salt  solution,  avoiding 
the  use  of  alcohol,  ether,  or 


HOW  TO 
INOCULATE 


any  other  antiseptic  solution.  A  slight  scarification  should 
be  made,  which  should  penetrate  only  the  outer  layers  of 
the  skin,  great  care  being  taken  not  to  draw  any  blood. 
If  now  upon  the  scarified  spot  a  small  amount  of  the 
offending  food  protein  be  placed,  together  with  a  drop 
of  sterile  water,  a  reaction  will  take  place  at  the  site  of 
the  inoculation,  which  will  manifest  itself  by  the  appear- 
ance of  a  distinct  urticarial  wheal  within  five  minutes  to 
half  an  hour.  It  is  always  best  to  make  a  control  scarifi- 
cation on  which  merely  the  physiological  salt  solution  or 
the  sterile  water  should  be  placed.  No  untoward  results 
follow  such  inoculation  if  it  is  made  properly. 

To  remove  the  hypersensitiveness  to  a  protein,  either 
the  specific  protein  may  be  elim- 
inated from  the  diet,  or  immuni- 
zation may  be  brought  about  by 
feeding  the  patient  with  small  amounts  of  the  anaphylac- 
togenic  substance  until  he  becomes  fully  desensitized. 

The  Squibb  Laboratories  now  produce  potent   food 
allergens  in  large  variety,  the 

r     11  .  1       .  .-I]'. 

following  being  a  partial  list. 
A  complete  list  may  be  had 
upon  application. 


TREATMENT 


ALLERGENS 


Cow's  milk  (all  proteins)  ,  cow's  milk  casein,  cow's  milk 
albumin,  cow's  milk  globulin,  human  milk.  Egg  —  Egg 
(all  proteins),  Egg  white  (all  proteins),  egg  albumin, 
egg  yolk  (all  proteins),  egg  yolk  globulin.  Cereals  — 
Barley,  rice,  wheat,  corn,  rye,  oat.  Beverages  —  Coffee, 
tea,  cocoa.  Vegetables  —  Navy  bean,  lima  bean,  pea, 
asparagus,  spinach,  white  potato,  sweet  potato,  carrot, 
turnip,  tomato,  squash.  Fruit  —  Orange,  strawberry, 
blackberry,  raspberry,  cherry,  peach,  plum,  prune, 
banana,  watermelon,  canteloupe.  Meat  —  Beef,  lamb, 
mutton,  veal,  pork,  chicken,  horse.  Sea  Foods  —  Cod- 
fish, salmon,  lobster,  crab,  oyster,  clam.  Nuts  —  Peanut, 
chestnut,  English  walnut,  black  walnut,  hickory  nut, 
pecan,  almond,  butternut,  Brazil  nut. 


SQUIBB'S  MATERIA  MEDICA        537 
Squibb's  Anaesthetics 

The  Squibb  line  of  anaesthetics  include  Ether,  Chloro- 
form, Ethyl  Chloride,  and  Ethyl  Bromide.  Each  is 
made  in  one  quality  only,  the  best  possible  for  anaesthesia, 
so  when  "Squibb's"  is  had,  there  is  no  danger  from  an 
inferior  product. 

Ether  Squibb  is  made  only  in  the  Squibb  Labora- 
tories by  a  process  devised  by  Dr.  E.  R.  Squibb  and 
long  since  brought  to  practical  perfection.  Its  physical 
and  chemical  characteristics  were  determined  by  exhaus- 
tive clinical  experimentation.  Thus  the  Squibb  Ether 
has  always  proved  itself  the  best  for  anaesthesia  and  been 
recognized  as  the  standard. 

Chloroform  Squibb  is  made  in  the  Squibb  Labora- 
tories by  the  Squibb  process  and  purified  by  a  special 
process  devised  by  Dr.  E.  R.  Squibb.  The  outcome  of 
these  processes  is  a  chloroform  in  vital  respects  superior  to 
the  chloroform  of  the  U.  S.  P.  No  better  chloroform  for 
anaesthesia  can  be  made  than  Chloroform  Squibb. 

Ethyl  Chloride  Squibb  is  pure.  This  is  necessary 
if  it  is  for  anaesthesia  by  inhalation.  In  order  that  no 
mistake  be  possible,  Ethyl  Chloride  Squibb,  like  all 
other  products  of  the  Squibb  Laboratories,  is  made  in  one 
quality  only.  This  is  put  up  in  glass  tu-bes  to  prevent 
decomposition,  which  invariably  takes  place  in  a  metal 
container.  'These  tubes  are  of  two  kinds:  one  delivering 
a  quantity  of  ethyl  chloride  sufficient  for  producing  gen- 
eral anaesthesia,  but  too  large  a  quantity  for  freezing;  the 
other  delivering  a  quantity  the  most  economical  and  other- 
wise the  most  satisfactory  for  freezing  as  a  local  anaes- 
thetic, but  too  small  an  amount  for  general  anaesthesia. 
In  ordering,  the  purpose  for  which  the  product  is  intended 
should  be  mentioned,  although  the  quality  of  ethyl  chlor- 
ide is  the  same  in  both  cases. 

Ethyl  Bromide  Squibb  is  made  with  the  same  care 
as  are  the  other  Squibb  anaesthetics,  and  requires  no  more 
extended  description  than  is  found  on  page  78  of  this 
Materia  Medica. 

The  Medical  Department  of  E.  R.  Squibb  &  Sons 
has  prepared  several  monographs  on  inhalation  anaesthesia, 
copies  of  which  may  be  had  by  physicians  upon  their 
request. 


FEEDING 


538        SQUIBB'S  MATERIA  MEDICA 

Squibb's  Milk  Sugar 

Specially  prepared  and  purified  for  the  home  modifica- 
tion of  milk  for  infant  feeding.  It  is  obvious  that  for  so 
FOR  INFANT  important  a  purpose  as  infant 

feeding,  nothing  but  the  very 
highest  quality  of  Milk  Sugar 
should  be  used;  and  such  is 
Squibb's.  It  is  added  not  merely  to  sweeten  the  food 
and  render  it  more  palatable,  but  to  furnish  the  proper 
proportion  of  soluble  carbohydrates  necessary  for  the 
infant's  nutrition  and  growth. 

Cow's  milk  contains  between  2J/2  and  4  per  cent,  of 
proteins,  and  about  4^/2  Per  cent,  of  milk  sugar;  woman's 
milk  contains  only  1  j/2  per  cent,  of  proteins  and  7  per 
cent,  of  milk  sugar.  Hence  in  cow's  milk  there  is  an 
excess  of  proteins  and  a  deficiency  of  milk  sugar.  It  is 
therefore  necessary  to  dilute  the  cow's  milk,  in  order  to 
diminish  the  protein  content  (for  it  is  the  proteins  that 
cause  much  of  the  trouble  to  the  infant's  digestion)  ;  but 
this  dilution  also  lowers  the  percentage  of  milk  sugar, 
thus  further  increasing  the  original  deficiency  of  this 
constituent.  Hence  the  necessity  for  the  addition  of 
milk  sugar.  Squibb's  milk 
sugar  is  perfectly  free  from 


FREE  FROM 
BUTTER-FAT, 
STARCH  AND 
CANE  SUGAR 


butter-fat,  starch  and  cane 
sugar,  which  are  very  liable  to 
produce  gastric  fermentation ; 
and  it  is  also  free  from 
acids  and  other  foreign  substances  that  might  prove  in- 
jurious to  the  infant.  Squibb's  Milk  Sugar  is  in  the 
form  of  an  impalpable  powder,  having  been  bolted 
through  a  No.  120  silk  bolting  cloth;  and  it  exceeds  the 
most  exacting  recognized  tests  for  purity. 

Inasmuch  as  milk  sugar  readily  absorbs  odors  and 
moisture,  and  in  consequence  hereof  becomes  contaminated 
and  unfit  for  use,  the  Squibb  product  is  offered  only  in 
sealed  tins,  in  1  -Ib.  and  |/4-lb.  sizes,  and  not  in  paste- 
board boxes. 

Directions  for  preparing  modified  milk  are  printed  on 
the  cans.  Specify  Squibb's  when  ordering  milk  sugar, 
and  thereby  insure  obtaining  a  product  of  the  greatest 
merit  and  reliability. 


SQUIBB'S  MATERIA  MEDICA        539 

Squibb's  Digitalis  Products 

The  Squibb  Laboratories  make  use  of  only  the  choicest 
and  most  carefully  cured  Digitalis  leaves.  This  is  evi- 
denced by  the  beautiful  green  color  of  the  Squibb  fluid- 
extract  and  tinctures.  Each  shipment  of  leaves  is  care- 
fully examined  by  our  expert  pharmacognosists,  and  its 
freedom  from  admixture  with  foreign  leaves  and  other 
adulterants  is  assured.  After  the  leaves  have  passed  this 
examination,  a  liberal  sample  of  it  is  made  into  the  official 
tincture  and  is  then  tested  physiologically  according  to 
the  method  outlined  in  the  U.  S.  P.  If  the  finished  drug 
does  not  admirably  come  up  to  the  official  standard  in 
every  respect,  the  entire  lot  of  leaves  is  rejected.  As  a 
rule,  the  leaves  accepted  by  the  Squibb  Laboratories  are 
much  more  active  than  the  Pharmacopoeia  demands  and 
the  preparations  made  from  them  are  carefully  adjusted 
to  a  potency  of  25  per  cent,  above  the  official  standard. 
In  this  way  full  activity  and  uniformity  of  strength  are 
assured  for  such  an  important  product  as  Digitalis. 

Tincture  Digitalis  Squibb  is  assayed  not  only  by  the 
U.  S.  P.  method,  as  mentioned  above,  but  its  activity 
is  also  determined  by  the  "cat  method"  thus  giving  a 
double  check  on  its  physiological  activity. 

Fluid  Extract  Digitalis  Squibb  is  biologically  assayed 
by  the  same  double  checking  system  as  the  tincture  just 
mentioned. 

A  Fat-free  Tincture  Digitalis  is  supposed  to  be  borne 
better  by  the  stomach  than  is  the  ordinary  tincture,  there- 
fore the  _  Squibb  Laboratories  make  a  fat-free  tincture, 
which  should  be  specified  if  desired.  It  is  prepared  from 
leaves  from  which  the  fat  has  been  removed  by  a  method 
which  does  not  extract  or  otherwise  interfere  with  any  of 
the  proximate  principles.  It  is  of  the  same  strength  as 
the  U.  S.  P.  tincture,  and  is  physiologically  tested  by 
the  Hatcher  "cat  method"  and  adjusted  so  that  each  mil 
(Cc.)  represents  one  cat  unit  (Hatcher's  standard). 

Whole,  Ground,  or  Powdered  Digitalis  leaves,  and  a 
Soft  and  a  Powdered  Extract  Digitalis,  are  also  offered 
under  the  Squibb  label. 

For  complete  descriptions  see  Digitalis,  Extract  Digi- 
talis, Fluidextract  Digitalis  and  Tincture  Digitalis  titles 
in  Part  I  of  this  MATERIA  MEDICA. 


540        SQUIBB'S  MATERIA  MEDICA 

Squibb's  Household  Products 

There  are  many  articles  of  a  medicinal  and  semi- 
medicinal  nature  for  which  employment  is  found  in  every 
household.  For  the  toilet  there  are  numerous  articles 
whose  quality  should  be  of  the  best;  while  for  general 
household  purposes — cooking,  milk  modification,  disin- 
fection, etc. — the  purest  and  best  articles  are  needed. 
The  following  products  are  well  known  for  their  purity, 
uniformity  and  efficiency: 

Squibb's  Baling  Powder.  Absolutely  pure,  very  ac- 
tive, hence  economical  to  use. 

Squibb's  Cold  Cream.  A  superior  product,  safe  to 
use  wherever  Cold  Cream  is  required. 

Squibb's  Milk  Sugar.  Exceptionally  pure;  fine  pow- 
der. Especially  designed  for  milk  modification. 

Squibb's  Olive  Oil.  Best  Virgin;  free  from  adulter- 
ants; brilliant,  and  of  most  agreeable  taste. 

Squibb's  Pure  Spices.  Of  absolute  purity,  hence  of 
unusual  strength. 

Squibb's  Castor  Oil.  Scarcely  any  unpleasant  taste 
because  of  its  punty ;  well  borne,  effective. 

Squibb's  Cod  Liver  Oil.  Cold  pressed  "shore"  oil; 
almost  free  from  disagreeable  odor  and  taste. 

Squibb's  Benzoinated  Cream.  A  healing  salve  for 
chafed  surfaces,  sunburn,  cracked  lips,  etc. 

Squibb's  Flexible  Collodion.  Liquid  Court-Plaster. 
Impervious  coating  for  cuts;  does  not  crack. 

Squibb's  Magnesium  Sulphate.  Repurified;  a  distinc- 
tive quality  with  hardly  any  bitterness. 

Squibb's  Sodium  Bicarbonate.  Highest  purity,  hence 
bitterless  and  efficient. 

Squibb's  Sodium  Phosphate.  Arsenic-free,  therefore 
may  be  taken  freely  and  often,  without  harm. 

Squibb's  Solution  Hydrogen  Peroxide.  Of  excep- 
tional strength  and  keeping  qualities. 

Squibb's  Talcum  PoTvder.  Of  correct  composition ; 
free  from  starch,  chalk,  and  other  foreign  substances; 
impalpable,  neutral,  non-irritating. 

Squibb's  Zinc  Stearate.  Antiseptic,  water-shedding 
dusting  powder  for  infants  as  well  as  adults.  Scarcely 
visible  when  applied. 


SQUIBB'S  MATERIA  MEDICA        541 

Squibb's  Olive  Oil 

It  is  not  generally  known  that  much  of  what  is  sold 
as  "Olive  Oil"  or  Salad  Oil  is  nothing  but  cotton-seed 
oil  without' even  a  trace  of  olive  oil  in  it;  and  mixtures  of 
olive  oil  with  cotton-seed  or  peanut  oil  are  brazenly 
offered  as  pure  olive  oil. 

Squibb's  Olive  Oil  is  guar- 
anteed absolutely  free  from 
adulteration  and  meets  the  most 


ABSOLUTELY  PURE 
VIRGIN  OIL 


rigid  known  tests  for  perfect 
purity  as  well  as  regards  physical  characteristics.  It 
is  the  very  best  quality  of  what  is  known  as  Virgin  Olive 
Oil;  that  is,  the  first  oil  that  exudes  on  subjecting  the 
olives  to  gentle  pressure,  this  portion  representing  the  best, 
the  most  palatable  and  the  most  nutritious  oil.  Only  the 
full  grown,  perfectly  sound  olives  of  the  proper  blackish- 
violet  color  are  used,  all  bruised,  decayed  or  otherwise 
unsound  fruits  being  rejected.  Squibb's  Olive  Oil  is 
therefore  a  brilliant  oil  of  greenish-yellow  color,  and 
most  pleasant,  nutty  taste. 

Recently  olive  oil  has  come 
into  prominence  as  an  efficient 
means  of  quickly  restoring  the 


PROMPT  RESTORER 
OF  THE  OPSONIC 
INDEX 


opsonic  index  after  surgical 
anaethesias.  For  this  important 
purpose  only  a  perfectly  pure  quality  such  as  Squibb's 
answers;  an  article  laden  with  stearins  and  other  heavy 
impurities  is  but  slowly  absorbed  ancl  therefore  means 
loss  of  precious  time.  Why  take  any  risks? 

Squibb's  Olive  Oil  is  put  up  in  special  bottles  of  1 
pint,  |/2  pint  and  '/^  pint — full  measure,  and  can  be 
obtained  in  these  original  packages  at  all  first  class 
drug  stores.  It  should  be  kept  in  a  cool  place  as  all 
pure  olive  oil  solidifies  at  0°C. ;  gentle  heat  will  restore 
its  fluidity. 

An  interesting  monograph  en- 
titled "Surgical  Anaesthesia  in 
its  Relation  to  Immunity,"  giv- 
ing a  statement  of  recent  find- 
ings concerning  olive  oil  as  a  speedy  restorer  of  the 
patient's  power  to  resist  infection,  will  be  mailed  to 
physicians  on  application. 


AN  INTEREST- 
ING TREATISE 


542        SQUIBB'S  MATERIA  MEDICA 
Barium  Sulphate  Squibb 

For  X-Ray  Work 

Formerly  Barium  Sulphate  was  used  only  in  the  arts, 
and  not  in  or  on  the  human  body.  However,  latterly  it 
has  been  brought  forward  for  use  in  taking  X-Ray  pic- 
tures of  the  stomach  and  of  the  intestines.  Of  course,  for 
this  purpose  only  a  specially  prepared  quality  is  eligible, 
one  of  which  is  absolutely  free  from  soluble  barium  salts 
so  as  to  be  wholly  without  toxic  action.  Such  a  product 
is  Barium  Sulphate  Squibb  for  X-Ray  work.  This  is  pre- 
pared from  highly  pure  materials  and  most  carefully 
tested  chemically  and  spectroscopically  for  perfect  free- 
dom from  soluble  barium  salts  and  other  possibly  harmful 
impurities. 

Barium  Sulphate  Squibb  for  X-Ray  Work  occurs  as 
an  extremely  fine,  white,  odorless,  tasteless  and  relatively 
light  powder,  which  is  insoluble  in  water  and  the 
organic  solvents  as  well  as  in  acids  and  in  dilute 
alkalies.  It  therefore  passes  through  the  system  wholly 
unchanged  and  unabsorbed,  and  as  it  is  absolutely  free 
from  soluble  salts  there  is  no  possibility  of  untoward 
action. 

Barium  Sulphate  Squibb  is  used  in  1  0  to  50  per  cent, 
mixtures  for  X-Ray  esophogeal  and  gastro-intestinal  ex- 
aminations. A  suitable  test  meal  for  examination  of  the 
stomach  and  intestines  consists  of  a  mixture  of  Barium 
Sulphate  Squibb  5  oz.,  sugar  J/2  oz.,  cocoa  ^3  oz., 
cornmeal  J/2  oz.  and  water  7  fl.  oz.  The  sulphate  may 
be  considerably  increased  if  necessary. 

It  is  also  employed  in  opaque  enemas  where  shadow 
pictures  of  the  colon  and  intestines  are  desired.  Such 
an  enema  should  be  non-irritating  to  the  bowel ;  sufficiently 
large  to  fill  the  entire  bowel ;  fluid  enough  to  flow  freely 
and  fill  recesses,  yet  sufficiently  thick  to  hold  the  barium 
in  good  suspension. 

In  view  of  the  fact  that  many  grades  of  Barium  Sul- 
phate on  the  market  contain  soluble  barium  salts  and 
are  hence  dangerous  to  use,  care  should  be  taken  to 
clearly  specify  and  accept  only  Barium  Sulphate  Squibb 
for  X-Ray  work. 


SQUIBB'S  MATERIA  MEDICA        543 

Squibb's  Magnesia  Magma 

(MILK  OF  MAGNESIA  SQUIBB) 

Squibb's  Magnesia  Magma  is  an  official  product  con- 
taining only  the  pure  magnesium  hydroxide,  in  the  per- 
centage specified  in  the  U.  S.  P.  suspended  in  water 
and  conforming  in  all  respects  to  the  chemical  and  phy- 
sical tests  laid  down  by  that  authority,  but  is  superior 
to  the  U.  S.  P.  and  most  magnesia  magmas  as  shown 
below. 

The  Squibb  Magnesia  Magma  is  made  from  the 
highly  purified  Magnesium  Sulphate  Squibb  while  the 
U.  S.  P.  product  is  made  from  U.  S.  P.  grade  Mag- 
nesium Carbonate.  Both  processes  produce  the  hydrated 
magnesium  oxide  but  the  Squibb  product  finishes  velvety 
smooth  while  others  are  distinctly  gritty. 

Again,  the  Squibb  product  has  but  a  slight  alkaline 
taste  while  the  U.  S.  P.  article  and  most  other  market 
varieties  have  a  pronounced  alkaline  taste.  Two  promi- 
nent factors  contribute  to  these  distinct  advantages  of  the 
Squibb  Magnesia  Magma  over  others.  In  its  manufac- 
ture only  chemicals  of  Squibb  purity  are  used  and,  again, 
the  process  is  carried  out  under  the- most  exacting  condi- 
tions and  with  complete  control  from  first  to  last.  The 
elegance  of  the  product  shows  the  result. 

It  is  much  used  by  adults  for  fermentative  dyspepsia, 
quickly  correcting  conditions  arising  from  excessive  acid- 
ity, and  for  the  colic  of  infants  it  is  almost  a  specific.  It 
will  maintain  a  continuous-  alkaline  condition  in  the  mouth 
and  -hence  is  much  in  favor  as  a  dentrifice  overcoming  any 
acidity  present  in  the  mouth  and  dental  interspaces,  and 
thus  protecting  the  teeth  against  untimely  decay.  There- 
fore in  rational  therapeutics  it  is  indicated  in  erosion, 
for  gingival  caries,  in  tooth  caries  of  pregnancy,  and  all 
oral  pathological  conditions  due  to  hyperacidity  of  the 
mouth  secretions,  whether  of  local  or  systemic  origin. 

Squibb's  Magnesia  Magma  is  offered  in  |/2  pint  and 
in  1  pint  bottles,  its  continued  use  will  demonstrate  that 
it  is  a  highly  superior  product. 


544        SQUIBB'S  MATERIA  MEDICA 
Squibb's  Testing  Apparatus 

It  does  not  seem  to  be  generally  known  that  E.  R. 
Squibb  &  Sons  make  several  convenient  and  inexpensive 
pieces  of  apparatus  for  use  of  physicians  and  pharmacists. 
They  are  briefly  described  below. 

This  apparatus  stand  has 
been  in  use  in  the  Squibb  Labo- 
ratories for  years  and  has 
proved  very  satisfactory.  It 
consists  of  a  nickel-plated  up- 
right rod,  secured  in  an  iron  cylinder  base.  Its  advan- 
tages are  its  stability,  neat  appearance  and  compactness. 
The  usual  attachments  are  supported  by  the  rod.  Price 
$2.30. 

Supplied  in  a  neatly  packed 


SQUIBB'S  IM- 
PROVED AP- 
PARATUS STAND 


SQUIBB'S  SPE- 
CIFIC GRAVITY 
APPARATUS 


case  and  consists  of  a  thermom- 
eter, hydrometer  (urinometer), 
urine  jar  or  tube,  and  litmus 
paper.  The  urinometer  is  ad- 
justed to  read  accurately  without  corrections  at  the  con- 
venient temperature  of  25°  C.  Temperature  corrections 
can  easily  be  made  however  as  shown  in  the  accompany- 
ing directions.  The  complete  outfit  is  supplied  for  $2.25. 

This  consists  of  the  necessary 


SQUIBB'S 
SUGAR  TEST- 
ING OUTFIT 


solutions,  tubes  and  pipette  for 
performing  Fehling's  sugar  test 
— usually  used  on  urine  sam- 
ples. It  comprises  50.  mils 
(Cc.)  each  of  copper  sulphate  .solution  and  alkaline  tar- 
trate  solution,  together  with  two  test  tubes  and  a  1  mil 
pipette ;  all  packed  in  a  pasteboard  case.  Full  directions 
are  enclosed.  The  set  supplies  sufficient  fluid  for  several 
tests  and  extra  solutions  can  be  obtained  of  E.  R.  Squibb 
&  Sons  as  found  necessary.  Price  $1.00. 

SQUIBB'S  UREA  This    aPPara'us    consuls    of 

APPARATUS  l"e   necessary   pieces   and   solu- 

tions for  the  quantitative  estima- 
tion of  urea  by  the  hypobromite 
method  (or  hypochlorite  method  if  preferred).  The 
parts  are  complete  and  compact  and  sufficient  solution  is 
supplied  for  several  tests.  Extra  solutions  may  be  ob- 
tained of  E.  R.  Squibb  &  Sons  if  desired.  Price  $2.45. 


Squibb fs  mat aria 
356   medic a, 


1919 


RS 
356 
S77 
1919 


That  the  SQUIBB  products  cost  no 
more  than  other  makes,  except  in 
very  few  instances,  where  a  slight 
advance  over  ordinary  market  prices 
is  charged  for  the  reason  that  it  is 
impossible  to  furnish  the  Squibb 
Quality  at  a  price  lower  than  that 
we  make  at  time  of  delivery. 

That  the  SQUIBB  products  are  readily 
obtainable  under  the  original  Squibb 
label  in  all  parts  of  the  United  States 
at  the  prices  and  in  the  subdivisions 
named  in  the  foregoing  pages. 

That  the  SQUIBB  products  are  carried 
in  stock  by  wholesale  houses  every- 
where, and  can  be  supplied  by  the 
jobbers  as  promptly  as  any  other 
brand. 

,  A 

Therefore,  if  you  prefer  SQUIBB'S  to  other 
makes,  do  not  hesitate  to  demand  it,  wherever 
you  may  be  located;  and  see  to  it  that  your 
specification  is  obeyed.  Your  active  coopera- 
tion will  be  greatly  appreciated  by 

E.  R.  SQUIBB  &  SONS 

THE  LIBRARY 

.      UNIVEi  OF  CALIFORNIA 

•S    A1MOFJLFA 


UC  SOUTHERN  REGIONAL  LIBRARY  FACILITY 


•      ••        ••   •        ••  III      I   I  I     ||    |   |    HI 

A    001416847    o 

CONTENTS 


Part  I — -Drugs  and  Chemicals 

Official  Products,  and  Non-Official  Chemicals,  Phar- 
maceuticals and  Newer  Remedies.  Arranged  in 
Alphabetical  Order  1-297 

Part  II— Medicinal  Tablets 

Mouth  Tablets,  Hypodermic  Tablets,  Dispensing  Tablets, 
Ophthalmic  Tablets,  Tablet  Cases,  Lozenges  and 
Troches  % *...  29cM35 

Part  III — Biological  Products 

Antitoxins,    Serums,    Vaccines,    Leucocyte    Extract    and 

Thromboplastin ;    also   Biological   Therapeutic    Index.  .   436-^448 

Part  IV — Reagents,  Test  Solutions,  Etc. 

Analyzed  Reagents,  Test  Solutions,  Volumetric  Solutions 

and    Indicators    449-464 


Part  V — Veterinary  Products 

Hypodermic  Tablets,  Solution  Tablets,  Tablet  Case, 
Arrfi-Hog  Cholera  Se'rum,  Mallein,  Distemper  Vaccine, 
Distemper  Serum,  Tetanus  Antitoxin  and  Tuberculin  465-470 


Part  VI — Miscellaneous 

Glossary    of    Therapeutic    Terms 471 

The   Metric   System,  with   Table   of   Equivalents 478 

Thermometric    Equivalents    481 

Practical   Urinalysis,  with  Tests  Commonly   Employed.  .  482 

Volume  at  25°  C.  of   1    Ib.  Av.  of  Soirfe  Liquids 489 

Chart    of    Eruptive    Fevers 490 

Obstetrical    Calendars    492 

Drugs  That  Affect  the  Color  of  Urine 494 

Percentage    Solution    Table- . .  .. . .  ; .  . ;  ; 495 

Part  VII— Scientific  Notes 

Detailed  Information  Concerning  a  Number  of  Important 

Squibb  Products    496-544 


